Skip to Main content Skip to Navigation

Analyse de la fonction ventriculaire droite

Abstract : The right ventricle (RV) has been neglected for a long time by cardiologists. Only recently, it has been pointed out as yielding pronostic or diagnostic value in numerous clinical situations. This thesis, after a review of the different methods used to assess the right ventricular function, stresses the limitations of the two most used methods to assess RV function: 1) Long-axis contraction indices fail to predict ejection fraction in a volumetric overload situation. 2) Short-axis MRI relies upon a rather difficult manual contouring of the endocardium. The main variation in this contouring occurs in the infundibulum (40%) and in the basal part around the tricuspid valve (40%). Then, we propose a novel geometric indice, easy to compute during a MRI examination and aimed to select the patients needing an accurate RV study. This index was validated within 340 patients and reduced the operator time of 35% without inducing any diagnostic error. The last part of this thesis concerns tissue phase-mapping. High temporal resolution is the key point for the accuracy of myocardial velocities and can be achieved by a simple averaging during free-breathing at the expense of longer acquisitions.
Complete list of metadata

Cited literature [115 references]  Display  Hide  Download
Contributor : Laurent Bonnemains <>
Submitted on : Wednesday, March 13, 2013 - 4:21:21 PM
Last modification on : Tuesday, October 13, 2020 - 10:45:34 AM
Long-term archiving on: : Friday, June 14, 2013 - 6:50:23 AM


  • HAL Id : tel-01749603, version 2


Bonnemains Laurent. Analyse de la fonction ventriculaire droite. Cardiologie et système cardiovasculaire. Université de Lorraine, 2012. Français. ⟨NNT : 2012LORR0187⟩. ⟨tel-01749603v2⟩



Record views


Files downloads