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Theses

Analyse de la fonction ventriculaire droite

Abstract : The right ventricle (RV) has been neglected for a long time by cardiologists. Only recently, it has been pointed out as yielding pronostic or diagnostic value in numerous clinical situations. This thesis, after a review of the different methods used to assess the right ventricular function, stresses the limitations of the two most used methods to assess RV function: 1) Long-axis contraction indices fail to predict ejection fraction in a volumetric overload situation. 2) Short-axis MRI relies upon a rather difficult manual contouring of the endocardium. The main variation in this contouring occurs in the infundibulum (40%) and in the basal part around the tricuspid valve (40%). Then, we propose a novel geometric indice, easy to compute during a MRI examination and aimed to select the patients needing an accurate RV study. This index was validated within 340 patients and reduced the operator time of 35% without inducing any diagnostic error. The last part of this thesis concerns tissue phase-mapping. High temporal resolution is the key point for the accuracy of myocardial velocities and can be achieved by a simple averaging during free-breathing at the expense of longer acquisitions
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https://hal.univ-lorraine.fr/tel-01749603
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  • HAL Id : tel-01749603, version 1

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Laurent Bonnemains. Analyse de la fonction ventriculaire droite. Médecine humaine et pathologie. Université de Lorraine, 2012. Français. ⟨NNT : 2012LORR0187⟩. ⟨tel-01749603v1⟩

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