Inhalation therapy: Inhaled corticosteroids in ENT, development and technical challenges of powder inhalers, nebulisers synchronized with breathing and aerosol size distribution

P. Le Guen (1) , N. Peron (2) , M. Durand (3, 4) , J. Pourchez (5, 4) , P. Cavaillon , G. Reychler (6) , L. Vecellio (7, 8) , J.C. Dubus (9)

1 HEGP - Hôpital Européen Georges Pompidou [APHP]
2 Service de pneumologie B
3 Centre Hospitalier Emile Roux [AP-HP]
4 LINA-ENSMSE - Laboratoire Interdisciplinaire d'Etude des Nanoparticules Aérosolisées
5 CIS-ENSMSE - Centre Ingénierie et Santé
6 Service Pneumologie Cliniques Universitaires Saint Luc
7 DTF-Aerodrug
8 PRPA - Pathologies Respiratoires : Protéolyse et Aérosolthérapie
9 Médecine Infantile [Hôpital Nord - APMH]

The working group on aerosol therapy (GAT) of the Société de Pneumologie de Langue Française (SPLF) has organized its third Aerosolstorming in 2012. During one single day, different aspects of inhaled therapies have been treated and are detailed in two articles, this one being the second. This text deals with the indications of inhaled corticosteroids in ENT, the development and technical challenges of powder inhalers, the advantages and disadvantages of each type of technologies to measure the particle sizes of inhaled treatments.

Mots clés: Inhaled treatment; Particle size distribution; Nasal spray; Dry-powder inhalers

Domaines: Médecine humaine et pathologie; Toxicologie; Génie des procédés

P. Le Guen, N. Peron, M. Durand, J. Pourchez, P. Cavaillon, et al.. Inhalation therapy: Inhaled corticosteroids in ENT, development and technical challenges of powder inhalers, nebulisers synchronized with breathing and aerosol size distribution. Revue des Maladies Respiratoires, 2013, 30 (8), pp.657-668. ⟨10.1016/j.rmr.2013.09.006⟩. ⟨hal-01139226⟩