Skip to Main content Skip to Navigation
Journal articles

Accelerated growth rate induced by neonatal high-protein milk formula is not supported by increased tissue protein synthesis in low-birth-weight piglets

Abstract : Low-birth-weight neonates are routinely fed a high-protein formula to promote catch-up growth and antibiotics are usually associated to prevent infection. Yet the effects of such practices on tissue protein metabolism are unknown. Baby pigs were fed from age 2 to 7 or 28 d with high protein formula with or without amoxicillin supplementation, in parallel with normal protein formula, to determine tissue protein metabolism modifications. Feeding high protein formula increased growth rate between 2 and 28 days of age when antibiotic was administered early in the first week of life. This could be explained by the occurrence of diarrhea when piglets were fed the high protein formula alone. Higher growth rate was associated with higher feed conversion and reduced protein synthesis rate in the small intestine, muscle and carcass, whereas proteolytic enzyme activities measured in these tissues were unchanged. In conclusion, accelerated growth rate caused by high protein formula and antibiotics was not supported by increased protein synthesis in muscle and carcass.
Document type :
Journal articles
Complete list of metadatas

Cited literature [35 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-01210293
Contributor : Archive Ouverte Prodinra <>
Submitted on : Thursday, May 28, 2020 - 8:57:54 PM
Last modification on : Friday, January 22, 2021 - 9:16:10 AM

File

545341_1.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Agnès Jamin, Bernard Sève, Jean-Noel Thibault, Nathalie Le Floc'H-Burban. Accelerated growth rate induced by neonatal high-protein milk formula is not supported by increased tissue protein synthesis in low-birth-weight piglets. Journal of Nutrition and Metabolism, 2012, 2012, ⟨10.1155/2012/545341⟩. ⟨hal-01210293⟩

Share

Metrics

Record views

150

Files downloads

49