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Importance de l'homéostasie du NAD dans la productivité et la résistance aux stress chez Arabidospis thaliana

Abstract : The harmonious development and functioning of plants depend on severalcofactors such asnicotinamide adenine dinucleotide. Besides its roles in redox recycling,the NAD is alsoinvolved in cellular signalling processes, which are central actors instress situations. TheNAD is thus one of the main determinants of plant energy homeostasis,and therefore of cropyield. Through a reverse genetics approach targeting the L-aspartateoxidase (AO) – the firstcommitted enzyme of NAD biosynthesis – plants with constitutive eitherincreased ordecreased levels of pyridine nucleotides have been obtained. A furtherstudy of these plantsenabled to show that the NAD (1) can improve the growth, development andproductivity ofplants, (2) coordinates photosynthetic, respiratory and nitrogenmetabolisms, and (3) actsupon biotic and abiotic stress resistance mechanisms. This research isbeing valuedindustrially.
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Linda de Bont. Importance de l'homéostasie du NAD dans la productivité et la résistance aux stress chez Arabidospis thaliana. Sciences agricoles. Université Paris Sud - Paris XI, 2014. Français. ⟨NNT : 2014PA112283⟩. ⟨tel-02970320⟩

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