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Etude des fonctions frontales dans la maladie d’Alzheimer : impact sur l’autonomie et les interactions communicationnelles

Abstract : The aim of our PhD work is to enrich the clinical presentation of frontal origin neurocognitive disorders through the assessment of frontal functions and communicational interactions in Alzheimer's disease. We propose an integrated approach of executive functioning, which comes out of isolated and singular studies that do not allow a global approach of all the competences supported by the frontal lobes. Executive functioning is essential to act on the environment but also to be adapted socially. Behavioral disturbances can therefore be different according to the modified or injured brain region (Stuss et al., 2002), leading to the need of integrating the notion of fractional frontal operation in theoretical models (Stuss & Alexander, 2007). Thus, we relied on the neuroanatomical model of frontal functions proposed by Stuss (2011) to better understand the behavioral, socioemotional and cognitive changes in people with Alzheimer disease; Actually, until now, no work has allowed to assess all these skills from the same sample of people with Alzheimer disease. To have a better understanding of the pathological dimensions, we will analyze the performances obtained in Alzheimer's disease, but also in the context of normal aging. Then, we will search the impact of the frontal functions on the loss of autonomy and social isolation. Finally, we will point out the links between the frontal functions and the communication, which will lead us to a better identification of the components necessary to the success of the social and communication interactions, and this, to propose adapted ways of interventions
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Sonia Michalon. Etude des fonctions frontales dans la maladie d’Alzheimer : impact sur l’autonomie et les interactions communicationnelles. Psychologie. Université d'Angers, 2018. Français. ⟨NNT : 2018ANGE0073⟩. ⟨tel-02957685⟩

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