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L'effet hypoalgésique de la manipulation vertébrale

Abstract : Spinal manipulation is known for its clinical effect on musculoskeletal pain. Or, its mechanisms of action on pain are still little known. This is why this doctoral project sought to determine the existence of a specific effect on the threshold of pressure pain, in asymptomatic subjects, and if it exists, to specify its size and its duration. Our two systematic and critical reviews of the literature have highlighted the presence of a specific regional effect of vertebral manipulation on this painful perception in the asymptomatic population, with a medium effect size and short duration. However, these results contradict our experimental trial on the effect of placebo-controlled thoracic spinal manipulation in this population. This difference can be explained by the quality of the placebo maneuver, with the verification of successful blindness during the experiment by a questionnaire. In conclusion, our work has not succeeded in reproducing a specific effect of vertebral manipulation on the threshold of pain perception at pressure, suggesting that the mechanisms of action of manipulation are similar to those in a placebo maneuver. Therefore, the main importance of the work is to have shown the importance of the placebo effect and commenting on the results of a trial may depend on the way the placebo intervention is performed and indicated.
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Submitted on : Friday, September 18, 2020 - 11:21:08 AM
Last modification on : Wednesday, October 14, 2020 - 4:21:42 AM


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  • HAL Id : tel-02942725, version 1


Margaux Honoré. L'effet hypoalgésique de la manipulation vertébrale. Médecine humaine et pathologie. Université Paris-Saclay, 2020. Français. ⟨NNT : 2020UPASS131⟩. ⟨tel-02942725⟩



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