S. Abdo-salem, A. Waret-szkuta, F. Roger, M. M. Olive, K. Saeed et al., Risk assessment of the introduction of Rift Valley fever from the Horn of Africa to Yemen via legal trade of small ruminants, Trop Anim Hlth Prod, vol.43, pp.471-80, 2011.

Z. Abera, H. Degefu, G. Gari, and M. Kidane, Sero-prevalence of lumpy skin disease in selected districts of West Wollega zone, BMC veterinary research, vol.11, p.135, 2015.

A. A. Abu-el-saad and A. As, Modulation of macrophage functions by sheeppox virus provides clues to understand interaction of the virus with host immune system, Virology journal, vol.2, p.22, 2005.

S. M. Abutarbush, M. M. Ababneh, A. Zoubi, I. G. , A. Sheyab et al., Lumpy Skin Disease in Jordan: Disease Emergence, Clinical Signs, Complications and Preliminaryassociated Economic Losses. Transboundary and emerging diseases, vol.62, pp.549-54, 2015.

S. M. Abutarbush, W. M. Hananeh, W. Ramadan, A. Sheyab, O. M. Alnajjar et al.,

, Adverse Reactions to Field Vaccination Against Lumpy Skin Disease in Jordan. Transboundary and emerging diseases, 2014.

H. A. Achour and R. Bouguedour, Epidemiology of sheep pox in Algeria, Revue Scientifique et Technique OIE, vol.18, pp.606-623, 1999.

H. A. Achour, R. Bouguedour, A. Bouhbal, A. Guechtouli, and M. Aouissat, Comparative study of the immunizing ability of some attenuated strains of sheep pox virus and of a sensitizing vaccine, Revue scientifique et technique (International Office of Epizootics), vol.19, issue.3, pp.773-83, 2000.

C. L. Afonso, E. R. Tulman, Z. Lu, L. Zsak, F. A. Osorio et al., The genome of swinepox virus, Journal of virology, vol.76, issue.2, pp.783-90, 2002.

. Aha-aha, Available at: wwwanimalhealthaustraliacomau/programs/emergency-animal-diseasepreparedness/ausvetplan, 2011.

K. A. Al-salihi and I. Q. Hassan, Lumpy Skin Disease in Iraq: Study of the Disease Emergence. Transboundary and emerging diseases, vol.62, pp.457-62, 2015.

A. Alcami, J. A. Symons, and G. L. Smith, The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral effects of IFN, Journal of virology, vol.74, issue.23, pp.11230-11239, 2000.

L. Aldaz-carroll, J. C. Whitbeck, M. Ponce-de-leon, H. Lou, L. Hirao et al., Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R, Journal of virology, vol.79, issue.10, pp.6260-71, 2005.

L. Aldaz-carroll, J. C. Whitbeck, M. Ponce-de-leon, H. Lou, L. K. Pannell et al., Physical and immunological characterization of a recombinant secreted form of the membrane protein encoded by the vaccinia virus L1R gene, Virology, vol.341, issue.1, pp.59-71, 2005.

L. Aldaz-carroll, Y. Xiao, J. C. Whitbeck, M. P. De-leon, H. Lou et al., Major neutralizing sites on vaccinia virus glycoprotein B5 are exposed differently on variola virus ortholog B6, Journal of virology, vol.81, issue.15, pp.8131-8140, 2007.

A. S. , Downstream processing needs a boost, Gen Eng News, vol.26, issue.1, pp.1-51, 2006.

M. A. Alkhamis and K. Vanderwaal, Spatial and Temporal Epidemiology of Lumpy Skin Disease in the Middle East, Front Vet Sci, vol.3, p.19, 2012.

V. Alva, S. Z. Nam, J. Soding, A. N. Lupas, R. Anandan et al., The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis, Studies on live and inactivated sheep pox vaccines. Cheiron. 1972: 1, vol.44, p.42, 2016.

P. H. Andersen, M. Nielsen, and O. Lund, Prediction of residues in discontinuous B-cell epitopes using protein 3D structures, Protein Science, vol.15, pp.2558-67, 2006.

A. Andreeva, D. Howorth, C. Chothia, E. Kulesha, and A. G. Murzin, SCOP2 prototype: a new approach to protein structure mining, Nucleic acids research, vol.42, pp.310-314, 2014.

J. Andrell and C. G. Tate, Overexpression of membrane proteins in mammalian cells for structural studies, Molecular membrane biology, vol.30, issue.1, pp.52-63, 2013.

C. H. Annandale, D. E. Holm, K. Ebersohn, and E. H. Venter, Seminal transmission of lumpy skin disease virus in heifers. Transboundary and emerging diseases, vol.61, pp.443-451, 2014.

. Anses, Risque d'introduction de la dermatose nodulaire contagieuse en France. Avis de l'Anses, Rapport d'expertise collective, 2017.

M. B. Appaiahgari and S. Vrati, Adenoviruses as gene/vaccine delivery vectors: promises and pitfalls, Expert opinion on biological therapy, vol.15, issue.3, pp.337-51, 2015.

P. A. Arlen, M. Singleton, J. J. Adamovicz, Y. Ding, A. Davoodi-semiromi et al., Effective plague vaccination via oral delivery of plant cells expressing F1-V antigens in chloroplasts, Infection and immunity, vol.76, issue.8, pp.3640-50, 2008.

K. Arnold, L. Bordoli, J. Kopp, and T. Schwede, The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling, Bioinformatics, vol.22, issue.2, pp.195-201, 2006.

K. Arnold, F. Kiefer, J. Kopp, J. N. Battey, M. Podvinec et al., The Protein Model Portal, Journal of structural and functional genomics, vol.10, issue.1, pp.1-8, 2009.

P. Artimo, M. Jonnalagedda, K. Arnold, D. Baratin, G. Csardi et al., SIB bioinformatics resource portal, vol.40, pp.597-603, 2012.

M. O. Asagba and D. R. Nawathe, Evidence of sheep pox in Nigeria. Tropical animal health and production, vol.13, p.61, 1981.

E. Assarsson, J. A. Greenbaum, M. Sundstrom, L. Schaffer, J. A. Hammond et al., Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes, Proceedings of the National Academy of Sciences of the United States of America, vol.105, issue.6, pp.2140-2145, 2008.

R. Assenberg, P. T. Wan, S. Geisse, and L. M. Mayr, Advances in recombinant protein expression for use in pharmaceutical research. Current opinion in structural biology, vol.23, pp.393-402, 2013.

M. G. Aucoin, J. A. Mena, and A. A. Kamen, Bioprocessing of baculovirus vectors: a review, Current gene therapy, vol.10, issue.3, pp.174-86, 2010.

E. Ayari-fakhfakh, T. Z. Valle, L. Guillemot, J. J. Panthier, M. Bouloy et al., MBT/Pas mouse: a relevant model for the evaluation of Rift Valley fever vaccines, The Journal of general virology, vol.93, pp.1456-64, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-00751378

G. Ayelet, Y. Abate, T. Sisay, H. Nigussie, E. Gelaye et al., Lumpy skin disease: preliminary vaccine efficacy assessment and overview on outbreak impact in dairy cattle at Debre Zeit, central Ethiopia, Antiviral research, vol.98, issue.2, pp.261-266, 2013.

M. D. Ayres, S. C. Howard, J. Kuzio, M. Lopez-ferber, and R. D. Possee, The complete DNA sequence of Autographa californica nuclear polyhedrosis virus, Virology, vol.202, issue.2, pp.586-605, 1994.
URL : https://hal.archives-ouvertes.fr/hal-02711096

S. Babiuk, T. R. Bowden, D. B. Boyle, D. B. Wallace, and R. P. Kitching, Capripoxviruses: an emerging worldwide threat to sheep, goats and cattle. Transboundary and emerging diseases, vol.55, pp.263-72, 2008.

S. Babiuk, G. Parkyn, J. Copps, J. E. Larence, M. I. Sabara et al., Evaluation of an ovine testis cell line (OA3.Ts) for propagation of capripoxvirus isolates and development of an immunostaining technique for viral plaque visualization, Inc, vol.19, issue.5, pp.486-91, 2007.

S. Babiuk, D. B. Wallace, S. J. Smith, T. R. Bowden, B. Dalman et al., Detection of antibodies against capripoxviruses using an inactivated sheeppox virus ELISA. Transboundary and emerging diseases, vol.56, pp.132-173, 2009.

I. V. Babkin and I. N. Babkina, The origin of the variola virus, Viruses, vol.7, issue.3, pp.1100-1112, 2015.

N. A. Baeshen, M. N. Baeshen, A. Sheikh, R. S. Bora, M. M. Ahmed et al., Cell factories for insulin production, Microbial cell factories, vol.13, p.141, 2014.

D. Baker and A. Sali, Protein structure prediction and structural genomics, Science, vol.294, issue.5540, pp.93-99, 2001.

V. Balamurugan, K. D. Jayappa, M. Hosamani, V. Bhanuprakash, G. Venkatesan et al.,

, Comparative efficacy of conventional and taqman polymerase chain reaction assays in the detection of capripoxviruses from clinical samples, Inc, vol.21, issue.2, pp.225-256, 2009.

C. A. Balinsky, G. Delhon, G. Smoliga, M. Prarat, R. A. French et al., Rapid preclinical detection of sheeppox virus by a real-time PCR assay, Journal of clinical microbiology, vol.46, issue.2, pp.438-480, 2008.

L. Balozet, Expériences sur la clavelée. Archives de l, Institut Pasteur de Tunis, vol.3, pp.245-53, 1931.

D. Barford, Y. Takagi, P. Schultz, and I. Berger, Baculovirus expression: tackling the complexity challenge. Current opinion in structural biology, vol.23, pp.357-64, 2013.

G. C. Barnard, G. E. Henderson, S. Srinivasan, and T. U. Gerngross, High level recombinant protein expression in Ralstonia eutropha using T7 RNA polymerase based amplification. Protein expression and purification, vol.38, pp.264-71, 2004.

B. M. Baroudy and B. Moss, Sequence homologies of diverse length tandem repetitions near ends of vaccinia virus genome suggest unequal crossing over, Nucleic acids research, vol.10, issue.18, pp.5673-5682, 1982.

B. M. Baroudy, S. Venkatesan, and B. Moss, Incompletely base-paired flip-flop terminal loops link the two DNA strands of the vaccinia virus genome into one uninterrupted polynucleotide chain, Cell, vol.28, issue.2, pp.315-339, 1982.

M. Bashton and C. Chothia, The generation of new protein functions by the combination of domains, Structure, vol.15, issue.1, pp.85-99, 1993.

J. J. Bass, D. J. Wilkinson, D. Rankin, B. E. Phillips, N. J. Szewczyk et al., An overview of technical considerations for Western blotting applications to physiological research. Scandinavian journal of medicine & science in sports, vol.27, pp.4-25, 2017.

E. Bell, M. Shamim, J. C. Whitbeck, G. Sfyroera, J. D. Lambris et al., Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin, Virology, vol.325, issue.2, pp.425-456, 2004.

J. Ben-gera, E. Klement, E. Khinich, Y. Stram, and N. Y. Shpigel, Comparison of the efficacy of Neethling lumpy skin disease virus and x10RM65 sheep-pox live attenuated vaccines for the prevention of lumpy skin disease -The results of a randomized controlled field study, Vaccine, vol.33, issue.38, pp.4837-4879, 2015.

F. Ben-chehida, A. Fakhfakh, P. Caufour, J. Amdouni, J. Nasr et al., Sheep pox in Tunisia: Current status and perspectives. Transboundary and emerging diseases, vol.2017, pp.1-14
URL : https://hal.archives-ouvertes.fr/pasteur-01553306

B. Dhia and M. L'élevage-ovin-en-tunisie, Situation actuelle et perspective d'avenir, L'élevage ovin en zones arides et semi arides Options Méditerranéennes CIHEAM-IAMZ, pp.9-20, 1995.

M. Benabdellah, E. Yajouri, and O. , Cost Benefit Analysis of Control Programs against Sheep pox in Morocco in a deterministic Environment, Journal of Inspiration Economy, vol.1, pp.27-39, 2016.

M. R. Benhnia, M. M. Mccausland, J. Moyron, J. Laudenslager, S. Granger et al., Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement, Journal of virology, vol.83, issue.3, pp.1201-1216, 2009.

I. N. Berezovsky, Discrete structure of van der Waals domains in globular proteins, Protein engineering, vol.16, issue.3, pp.161-168, 2003.

I. N. Berezovsky, E. Guarnera, Z. Zheng, I. N. Berezovsky, Z. Zheng et al., Basic units of protein structure, folding, and function. Progress in biophysics and molecular biology, Protein science : a publication of the Protein Society, vol.59, issue.9, pp.1475-85, 2015.

A. Berhanu, R. L. Wilson, D. L. Kirkwood-watts, D. S. King, T. K. Warren et al., Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge, Journal of virology, vol.82, issue.7, pp.3517-3546, 2008.

G. Berhe, C. Minet, L. Goff, C. Barrett, T. Ngangnou et al., Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections, Journal of virology, vol.77, issue.2, pp.1571-1578, 2003.

S. Bertagnoli, P. C. Poxvirus-;-lefèvre, J. Blancou, and R. Chermette, Principales maladies infectieuses et parasitaires du bétail: Europe et régions chaudes, Eds Tec & doc Tome, vol.1, pp.407-421, 2003.

L. R. Bertolini, H. Meade, C. R. Lazzarotto, L. T. Martins, K. C. Tavares et al., The transgenic animal platform for biopharmaceutical production, Transgenic research, vol.25, issue.3, pp.329-372, 2016.

V. Bhanot, V. Balamurugan, V. Bhanuprakash, G. Venkatesan, A. Sen et al., Expression of P32 protein of goatpox virus in Pichia pastoris and its potential use as a diagnostic antigen in ELISA, Journal of virological methods, vol.162, issue.1-2, pp.251-258, 2009.

V. Bhanuprakash, M. Hosamani, and R. K. Singh, Prospects of control and eradication of capripox from the Indian subcontinent: a perspective, Antiviral research, vol.91, issue.3, pp.225-257, 2011.

V. Bhanuprakash, B. K. Indrani, R. Hegde, M. M. Kumar, and A. R. Moorthy, A classical live attenuated vaccine for sheep pox. Tropical animal health and production, vol.36, pp.307-327, 2004.

V. Bhanuprakash, B. K. Indrani, M. Hosamani, and R. K. Singh, The current status of sheep pox disease. Comparative immunology, microbiology and infectious diseases, vol.29, pp.27-60, 2006.

Y. S. Binepal, F. A. Ongadi, and J. C. Chepkwony, Alternative cell lines for the propagation of lumpy skin disease virus. The Onderstepoort journal of veterinary research, vol.68, pp.151-154, 2001.

.. C. Bisbee, Current perspectives on manufacturing and scaleup of biopharmaceuticals, Gen Eng News, vol.13, pp.8-10, 1993.

H. Bisht, A. S. Weisberg, and B. Moss, Vaccinia virus l1 protein is required for cell entry and membrane fusion, Journal of virology, vol.82, issue.17, pp.8687-94, 2008.

J. Blancou, M. P. Kieny, R. Lathe, J. P. Lecocq, P. P. Pastoret et al., Oral vaccination of the fox against rabies using a live recombinant vaccinia virus, Nature, vol.322, issue.6077, pp.373-378, 1986.

R. Blasco, J. R. Sisler, and B. Moss, Dissociation of progeny vaccinia virus from the cell membrane is regulated by a viral envelope glycoprotein: effect of a point mutation in the lectin homology domain of the A34R gene, Journal of virology, vol.67, issue.6, pp.3319-3344, 1993.

R. E. Blouch, C. M. Byrd, and D. E. Hruby, Importance of disulphide bonds for vaccinia virus L1R protein function, Virology journal, vol.2, p.91, 2005.

A. Borrel, Etude experimentale de la clavelée. Filtration du virus; sero-clavelisation

I. Serotherapie-annls and . Pasteur, , pp.17-24, 1903.

H. Boshra, T. Truong, C. Nfon, T. R. Bowden, V. Gerdts et al., A lumpy skin disease virus deficient of an IL-10 gene homologue provides protective immunity against virulent capripoxvirus challenge in sheep and goats, Antiviral research, vol.123, pp.39-49, 2015.

H. Boshra, T. Truong, C. Nfon, V. Gerdts, S. Tikoo et al., Capripoxvirus-vectored vaccines against livestock diseases in Africa, Antiviral research, vol.98, issue.2, pp.217-244, 2013.

Z. Boumart, S. Daouam, I. Belkourati, L. Rafi, E. Tuppurainen et al., Comparative innocuity and efficacy of live and inactivated sheeppox vaccines, BMC veterinary research, vol.12, issue.1, p.133, 2016.

T. R. Bowden, S. L. Babiuk, G. R. Parkyn, J. S. Copps, and D. B. Boyle, Capripoxvirus tissue tropism and shedding: A quantitative study in experimentally infected sheep and goats, Virology, vol.371, issue.2, pp.380-93, 2008.

T. R. Bowden, B. E. Coupar, S. L. Babiuk, J. R. White, V. Boyd et al., Detection of antibodies specific for sheeppox and goatpox viruses using recombinant capripoxvirus antigens in an indirect enzyme-linked immunosorbent assay, Journal of virological methods, vol.161, issue.1, pp.19-29, 2009.

A. Brahmi and . .-l'élevage-ovin-laitier-en-tunisie, Analyse de la situation actuelle, contraintes, moyens et perspectives de développement. Thèse de doctorat en sciences agronomiques, Sciences de la production animale, 2008.

K. A. Bratke, A. Mclysaght, and S. Rothenburg, A survey of host range genes in poxvirus genomes

, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, vol.14, pp.406-431, 2013.

A. Breiman, D. C. Carpentier, H. A. Ewles, and G. L. Smith, Transport and stability of the vaccinia virus A34 protein is affected by the A33 protein, The Journal of general virology, vol.94, pp.720-725, 2013.

G. Brem, U. Besenfelder, and P. Hartl, Production of foreign proteins in the mammary gland of transgenic mammals, Chim Oggi, vol.11, issue.21, p.25, 1993.

J. Brenner, M. Bellaiche, E. Gross, D. Elad, Z. Oved et al., Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: statutory challenge, Vaccine, vol.27, issue.10, pp.1500-1503, 2009.

R. M. Buller, B. M. Arif, D. N. Black, K. R. Dumbell, J. J. Esposito et al., Virus Taxonomy: Classification and Nomenclature of Viruses. Eighth Report of the International Committee on Taxonomy of Viruses, pp.117-150, 2005.

C. Cameron, S. Hota-mitchell, C. L. Barrett, J. Cao, J. X. Macaulay et al., The complete DNA sequence of myxoma virus, Virology, vol.264, issue.2, pp.298-318, 1999.

J. X. Cao, P. D. Gershon, and D. N. Black, Sequence analysis of HindIII Q2 fragment of capripoxvirus reveals a putative gene encoding a G-protein-coupled chemokine receptor homologue, Virology, vol.209, issue.1, pp.207-219, 1995.

V. M. Carn, An antigen trapping ELISA for the detection of capripoxvirus in tissue culture supernatant and biopsy samples, Journal of virological methods, vol.51, issue.1, pp.95-102, 1995.

V. M. Carn, Control of capripoxvirus infections, Vaccine, vol.11, issue.13, pp.1275-1284, 1993.

V. M. Carn and R. P. Kitching, An investigation of possible routes of transmission of lumpy skin disease virus (Neethling). Epidemiology and infection, vol.114, pp.219-245, 1995.

V. M. Carn, R. P. Kitching, J. M. Hammond, and P. Chand, Use of a recombinant antigen in an indirect ELISA for detecting bovine antibody to capripoxvirus, Journal of virological methods, vol.49, issue.3, pp.285-94, 1994.

G. C. Carter, M. Law, M. Hollinshead, and G. L. Smith, Entry of the vaccinia virus intracellular mature virion and its interactions with glycosaminoglycans. The Journal of general virology, vol.86, pp.1279-90, 2005.

P. Caufour, T. Rufael, C. E. Lamien, R. Lancelot, M. Kidane et al., Protective efficacy of a single immunization with capripoxvirus-vectored recombinant peste des petits ruminants vaccines in presence of pre-existing immunity, Vaccine, vol.32, issue.30, pp.3772-3781, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02639522

G. Chakroun, Prédiction de la structure d'une protéine. Soluscience, 2009.

K. W. Chan, M. L. Lee, W. C. Yang, M. L. Wong, W. L. Hsu et al., Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, vol.26, issue.2, pp.195-202, 2014.

W. M. Chan, A. E. Kalkanoglu, and B. M. Ward, The inability of vaccinia virus A33R protein to form intermolecular disulfide-bonded homodimers does not affect the production of infectious extracellular virus, Virology, vol.408, issue.1, pp.109-127, 2010.

W. M. Chan and B. M. Ward, There is an A33-dependent mechanism for the incorporation of B5-GFP into vaccinia virus extracellular enveloped virions, Virology, vol.402, issue.1, pp.83-93, 2010.

P. Chand, R. P. Kitching, and D. N. Black, Western blot analysis of virus-specific antibody responses for capripox and contagious pustular dermatitis viral infections in sheep, Epidemiology and infection, vol.113, issue.2, pp.377-85, 1994.

T. H. Chang, S. J. Chang, F. L. Hsieh, T. P. Ko, C. T. Lin et al., Crystal structure of vaccinia viral A27 protein reveals a novel structure critical for its function and complex formation with A26 protein, PLoS pathogens, vol.9, issue.8, p.1003563, 2013.

N. Chen, R. M. Buller, E. M. Wall, and C. Upton, Analysis of host response modifier ORFs of ectromelia virus, the causative agent of mousepox, Virus research, vol.66, issue.2, pp.155-73, 2000.

Z. Chen, P. Earl, J. Americo, I. Damon, S. K. Smith et al., Characterization of chimpanzee/human monoclonal antibodies to vaccinia virus A33 glycoprotein and its variola virus homolog in vitro and in a vaccinia virus mouse protection model, Journal of virology, vol.81, issue.17, pp.8989-95, 2007.

Z. Chen, P. Earl, J. Americo, I. Damon, S. K. Smith et al., Chimpanzee/human mAbs to vaccinia virus B5 protein neutralize vaccinia and smallpox viruses and protect mice against vaccinia virus, Proceedings of the National Academy of Sciences of the United States of America, vol.103, issue.6, pp.1882-1889, 2006.

O. V. Chervyakova, V. L. Zaitsev, B. K. Iskakov, E. T. Tailakova, V. M. Strochkov et al., Recombinant Sheep Pox Virus Proteins Elicit Neutralizing Antibodies, Viruses, vol.8, issue.6, 2016.

C. M. Chihota, L. F. Rennie, R. P. Kitching, and P. S. Mellor, Mechanical transmission of lumpy skin disease virus by Aedes aegypti (Diptera: Culicidae), Epidemiology and infection, vol.126, issue.2, pp.317-338, 2001.

Y. C. Ching, C. S. Chung, C. Y. Huang, Y. Hsia, Y. L. Tang et al., Disulfide bond formation at the C termini of vaccinia virus A26 and A27 proteins does not require viral redox enzymes and suppresses glycosaminoglycan-mediated cell fusion, Journal of virology, vol.83, issue.13, pp.6464-76, 2009.

F. I. Chu, Y. Ho, and D. L. Tzou, NMR assignment of the vaccinia virus envelope protein A27L, Journal of biomolecular NMR, vol.32, issue.2, p.178, 2005.

G. Chu, H. Hayakawa, and P. Berg, Electroporation for the efficient transfection of mammalian cells with DNA, Nucleic acids research, vol.15, issue.3, pp.1311-1337, 1987.

Y. Chu, X. Yan, P. Gao, P. Zhao, Y. He et al., Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, vol.23, issue.4, pp.786-795, 2011.

C. S. Chung, C. H. Chen, M. Y. Ho, C. Y. Huang, C. L. Liao et al., Vaccinia virus proteome: identification of proteins in vaccinia virus intracellular mature virion particles, Journal of virology, vol.80, issue.5, pp.2127-2167, 2006.

C. S. Chung, J. C. Hsiao, Y. S. Chang, and W. Chang, A27L protein mediates vaccinia virus interaction with cell surface heparan sulfate, Journal of virology, vol.72, issue.2, pp.1577-85, 1998.

J. Coetzer, Lumpy skin disease. Infectious diseases of livestock, vol.2, pp.1268-1276, 2004.

M. E. Cohen, Y. Xiao, R. J. Eisenberg, G. H. Cohen, and S. N. Isaacs, Antibody against extracellular vaccinia virus (EV) protects mice through complement and Fc receptors, PloS one, vol.6, issue.6, p.20597, 2011.

A. Contreras-gomez, A. Sanchez-miron, F. Garcia-camacho, E. Molina-grima, and Y. Chisti, Protein production using the baculovirus-insect cell expression system, Biotechnology progress, vol.30, issue.1, pp.1-18, 2014.

C. Dadousis, ) retrospective study, Sheep pox in Evros. A 7-year, vol.54, pp.172-80, 1994.

S. Dales, Effects of streptovitacin A on the initial events in the replication of vaccinia and reovirus, Proceedings of the National Academy of Sciences of the United States of America, vol.54, issue.2, pp.462-470, 1965.

S. Dales and E. H. Mosbach, Vaccinia as a model for membrane biogenesis, Virology, vol.35, issue.4, pp.564-83, 1968.

S. Dales and L. Siminovitch, The development of vaccinia virus in Earle's L strain cells as examined by electron microscopy, The Journal of biophysical and biochemical cytology, vol.10, pp.475-503, 1961.

I. K. Damon, D. M. Poxviruses-;-knipe, P. M. Howley, D. E. Griffin, and R. A. Lamb, Fields Virology, pp.2947-75, 2007.

A. Das, S. Babiuk, and M. T. Mcintosh, Development of a loop-mediated isothermal amplification assay for rapid detection of capripoxviruses, Journal of clinical microbiology, vol.50, issue.5, pp.1613-1633, 2012.

R. Das and D. Baker, Macromolecular modeling with rosetta. Annual review of biochemistry, vol.77, pp.363-82, 2008.

M. Dashprakash, G. Venkatesan, M. A. Ramakrishnan, D. Muthuchelvan, M. Sankar et al., Genetic diversity of fusion gene (ORF 117), an analogue of vaccinia virus A27L gene of capripox virus isolates, Virus genes, vol.50, issue.2, pp.325-333, 2015.

D. H. Davies, D. M. Molina, J. Wrammert, J. Miller, S. Hirst et al., Proteome-wide analysis of the serological response to vaccinia and smallpox, Proteomics, vol.7, issue.10, pp.1678-86, 2007.

F. G. Davies, Characteristics of a virus causing a pox disease in sheep and goats in Kenya, with observation on the epidemiology and control, The Journal of hygiene, vol.76, issue.2, pp.163-71, 1976.

F. G. Davies, Lumpy skin disease, an African capripox virus disease of cattle. The British veterinary journal, vol.147, pp.489-503, 1991.

F. G. Davies and C. Otema, Relationships of capripox viruses found in Kenya with two Middle Eastern strains and some orthopox viruses. Research in veterinary science, vol.31, pp.253-258, 1981.

A. De-castilho-fernandes, A. Fontes, N. Gonsales, K. Swiech, V. Picanco-castro et al., Stable and high-level production of recombinant Factor IX in human hepatic cell line, Biotechnology and applied biochemistry, vol.58, issue.4, pp.243-252, 2011.

A. De-marco, Strategies for successful recombinant expression of disulfide bond-dependent proteins in Escherichia coli, Microbial cell factories, vol.8, p.26, 2009.

M. De-virgilio, D. Marchis, F. Bellucci, M. Mainieri, D. Rossi et al., The human immunodeficiency virus antigen Nef forms protein bodies in leaves of transgenic tobacco when fused to zeolin, Journal of experimental botany, vol.59, issue.10, pp.2815-2844, 2008.

A. M. Delange and G. Mcfadden, The role of telomeres in poxvirus DNA replication. Current topics in microbiology and immunology, vol.163, pp.71-92, 1990.

S. Delhaye, S. Paul, C. Sommereyns, V. Van-pesch, and T. Michiels, Les interférons de type I, Virologie, vol.10, pp.167-78, 2006.

G. Delhon, E. R. Tulman, C. L. Afonso, Z. Lu, A. De-la-concha-bermejillo et al., Genomes of the parapoxviruses ORF virus and bovine papular stomatitis virus, Journal of virology, vol.78, issue.1, pp.168-77, 2004.

A. L. Demain and P. Vaishnav, Production of recombinant proteins by microbes and higher organisms, Biotechnology advances, vol.27, issue.3, pp.297-306, 2009.

W. E. Demkowicz, J. S. Maa, and M. Esteban, Identification and characterization of vaccinia virus genes encoding proteins that are highly antigenic in animals and are immunodominant in vaccinated humans, Journal of virology, vol.66, issue.1, pp.386-98, 1992.

, DGSV. Direction Générale des Services Vétérinaires Tunisiens. Ministère de l'Agriculture. Annual reports, 2009.

. Dgsv, Direction Générale des Services Vétérinaires Tunisiens. Ministère de l'Agriculture. Annual report Rapport variole ovine Situation sanitaire, vol.207, pp.1-21, 2010.

A. Diallo and G. J. Viljoen, Genus Capripoxvirus, pp.167-81, 2007.

A. Diallo, C. Minet, G. Berhe, L. Goff, C. Black et al., Goat immune response to capripox vaccine expressing the hemagglutinin protein of peste des petits ruminants, Annals of the New York Academy of Sciences, vol.969, pp.88-91, 2002.

V. Doceul, M. Hollinshead, L. Van-der-linden, and G. L. Smith, Repulsion of superinfecting virions: a mechanism for rapid virus spread, Science, vol.327, issue.5967, pp.873-879, 2010.
URL : https://hal.archives-ouvertes.fr/hal-02814651

S. K. Doke and S. C. Dhawale, Alternatives to animal testing: A review. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, vol.23, pp.223-232, 2015.

J. Domenech, J. Lubroth, C. Eddi, V. Martin, and F. Roger, Regional and international approaches on prevention and control of animal transboundary and emerging diseases, AnnNY Acad Sci, vol.1081, pp.90-107, 2006.

O. Dor and Y. Zhou, Real-SPINE: an integrated system of neural networks for real-value prediction of protein structural properties, Proteins, vol.68, issue.1, pp.76-81, 2007.

A. Dove, Uncorking the biomanufacturing bottleneck, Nature biotechnology, vol.20, issue.8, pp.777-786, 2002.

D. Scas and A. M. , Live and inactivated tissue culture vaccines against goat-pox, Indian Vet J, vol.65, p.925, 1978.

S. Duraffour, G. Andrei, and R. Snoeck, Nouvelles armes thérapeutiques contre les poxvirus, Virologie, vol.12, issue.5, pp.323-361, 2008.

A. K. Earley, W. M. Chan, and B. M. Ward, The vaccinia virus B5 protein requires A34 for efficient intracellular trafficking from the endoplasmic reticulum to the site of wrapping and incorporation into progeny virions, Journal of virology, vol.82, issue.5, pp.2161-2170, 2008.

. Efsa-ap, EFSA Panel on Animal Health and Welfare. Scientific Opinion on sheep and goat pox, EFSA Journal, vol.12, p.3885

A. Egli, A. Levin, D. M. Santer, M. Joyce, O. Shea et al., Immunomodulatory Function of Interleukin 28B during primary infection with cytomegalovirus. The Journal of infectious diseases, vol.210, pp.717-744, 2014.

C. Embury-hyatt, S. Babiuk, L. Manning, S. Ganske, T. R. Bowden et al., Pathology and viral antigen distribution following experimental infection of sheep and goats with capripoxvirus, Journal of comparative pathology, vol.146, issue.2-3, pp.106-121, 2012.

. Empres and . Transboundary, Animal Diseases Bulletin. Division: Animal Production and Health Division, 1999.

M. Engelstad, S. T. Howard, and G. L. Smith, A constitutively expressed vaccinia gene encodes a 42-kDa glycoprotein related to complement control factors that forms part of the extracellular virus envelope, Virology, vol.188, issue.2, pp.801-811, 1992.

M. Engelstad and G. L. Smith, The vaccinia virus 42-kDa envelope protein is required for the envelopment and egress of extracellular virus and for virus virulence, Virology, vol.194, issue.2, pp.627-664, 1993.

J. J. Esposito, S. A. Sammons, A. M. Frace, J. D. Osborne, M. Olsen-rasmussen et al., Genome sequence diversity and clues to the evolution of variola (smallpox) virus, Science, vol.313, issue.5788, pp.807-819, 2006.

K. Essani, R. Dugre, and S. Dales, Biogenesis of vaccinia: involvement of spicules of the envelope during virion assembly examined by means of conditional lethal mutants and serology, Virology, vol.118, issue.2, pp.279-92, 1982.

S. Fagbo, J. A. Coetzer, and E. H. Venter, Seroprevalence of Rift Valley fever and lumpy skin disease in African buffalo (Syncerus caffer) in the Kruger National Park and Hluhluwe-iMfolozi Park, South Africa, Journal of the South African Veterinary Association, vol.85, issue.1, p.1075, 2014.

E. Fakhfakh, L. Goff, C. , A. E. Zekri, S. Sghaier et al., Isolement et étude moléculaire de souches des virus de la clavelée et de l'ecthyma contagieux en Tunisie. Revue Élev Méd Vét Pays trop, vol.58, pp.7-14, 2005.

F. G. Falkner and G. W. Holzer, Vaccinia viral/retroviral chimeric vectors, Current gene therapy, vol.4, issue.4, pp.417-443, 2004.

M. Fang, H. Cheng, Z. Dai, Z. Bu, and L. J. Sigal, Immunization with a single extracellular enveloped virus protein produced in bacteria provides partial protection from a lethal orthopoxvirus infection in a natural host, Virology, vol.345, issue.1, pp.231-274, 2006.

. Fao-oie-who, The FAO-OIE-WHO collaboration. Sharing responsibilities and coordinating global activities to address health risks at the animal-human-ecosystems interfaces: A tripartite concept note, 2010.

M. C. Feiten, D. Luccio, M. Santos, K. F. De-oliveira, D. Oliveira et al., X-Ray Crystallography as a Tool to Determine Three-Dimensional Structures of Commercial Enzymes Subjected to Treatment in Pressurized Fluids. Applied biochemistry and biotechnology, 2016.

R. D. Ferris and W. Plowright, Simplified methods for the production of monolayers of testis cells from domestic animals, and for the serial examination of monolayer cultures, The Journal of pathology and bacteriology, vol.75, issue.2, pp.313-321, 1958.

E. Fèvre, B. Bronsvoort, K. Hamilton, and S. Cleaveland, Animal movements and the spread of infectious diseases, Trends in microbiology, vol.14, pp.125-156, 2006.

B. Fischer, I. Sumner, and P. Goodenough, Isolation, renaturation, and formation of disulfide bonds of eukaryotic proteins expressed in Escherichia coli as inclusion bodies, Biotechnology and bioengineering, vol.41, issue.1, pp.3-13, 1993.

J. Fisher,

D. Fitzgerald, Revving up the green express, Scientist, vol.17, issue.14, pp.45-52, 2003.

S. J. Flint, L. W. Enquist, and V. R. Racaniello, Skalka AM. Principles of Virology: Molecular Biology, Pathogenesis, and Control of Animal Viruses, 2003.

C. Fogg, S. Lustig, J. C. Whitbeck, R. J. Eisenberg, G. H. Cohen et al., Protective immunity to vaccinia virus induced by vaccination with multiple recombinant outer membrane proteins of intracellular and extracellular virions, Journal of virology, vol.78, issue.19, pp.10230-10237, 2004.

C. N. Fogg, J. L. Americo, S. Lustig, J. W. Huggins, S. K. Smith et al., Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges, Vaccine, vol.25, issue.15, pp.2787-99, 2007.

C. H. Foo, H. Lou, J. C. Whitbeck, M. Ponce-de-leon, D. Atanasiu et al., Vaccinia virus L1 binds to cell surfaces and blocks virus entry independently of glycosaminoglycans, Virology, vol.385, issue.2, pp.368-82, 2009.

C. H. Foo, J. C. Whitbeck, M. Ponce-de-leon, W. T. Saw, G. H. Cohen et al., The myristate moiety and amino terminus of vaccinia virus l1 constitute a bipartite functional region needed for entry, Journal of virology, vol.86, issue.10, pp.5437-51, 2012.

C. A. Franke, P. L. Reynolds, and D. E. Hruby, Fatty acid acylation of vaccinia virus proteins, Journal of virology, vol.63, issue.10, pp.4285-91, 1989.

S. Fulzele, R. K. Singh, M. Hosamani, B. Mondal, and M. P. Yadav, Evaluation of duplex PCR and PCR-RFLP for diagnosis of sheep pox and goat pox, Int J TropMed, vol.1, issue.2, pp.66-70, 2006.

P. Galea, L. Kellya, and E. L. Snarya, Qualitative assessment of the entry of capripoxviruses into Great Britain from the European Union through importation of ruminant hides,skins and wool. Microbial Risk analysis, vol.1, pp.13-21, 2016.

M. C. Galmiche, J. Goenaga, R. Wittek, and L. Rindisbacher, Neutralizing and protective antibodies directed against vaccinia virus envelope antigens, Virology, vol.254, issue.1, pp.71-80, 1999.

G. Gari, G. Abie, D. Gizaw, A. Wubete, M. Kidane et al., Evaluation of the safety, immunogenicity and efficacy of three capripoxvirus vaccine strains against lumpy skin disease virus, Vaccine, vol.33, issue.28, pp.3256-61, 2015.

G. Gari, F. Biteau-coroller, C. Legoff, P. Caufour, and F. Roger, Evaluation of indirect fluorescent antibody test (IFAT) for the diagnosis and screening of lumpy skin disease using Bayesian method. Veterinary microbiology, vol.129, pp.269-80, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00532374

G. Gari, V. Grosbois, A. Waret-szkuta, S. Babiuk, P. Jacquiet et al., Lumpy skin disease in Ethiopia: seroprevalence study across different agro-climate zones, Acta tropica, vol.123, issue.2, pp.101-107, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02646955

A. Gavinelli and D. Dilaveris, European Union Lumpy Skin Disease and other exotic diseases antigen/vaccine banks. Current status, policy and future considerations: Stakeholder focus group meeting on availability of Lumpy Skin Disease (LSD) vaccines authorised to EU standards European Medicines Agency, 2017.

S. Geisse, Insect Cell Cultivation and Generation of Recombinant Baculovirus Particles for Recombinant Protein Production, In Animal Cell Biotechnology: Methods and Protocols, vol.24, pp.489-507, 2007.

E. Gelaye, A. Belay, G. Ayelet, S. Jenberie, M. Yami et al., Capripox disease in Ethiopia: Genetic differences between field isolates and vaccine strain, and implications for vaccination failure, Antiviral research, vol.119, pp.28-35, 2015.

P. D. Gershon, D. M. Ansell, and D. N. Black, A comparison of the genome organization of capripoxvirus with that of the orthopoxviruses, Journal of virology, vol.63, issue.11, pp.4703-4711, 1989.

A. Ghanadan, A. Saghazadeh, I. Jahanzad, and N. Rezaei, Clinical aspects of indirect immunofluorescence for autoimmune diseases, Expert review of clinical immunology, vol.11, issue.5, pp.597-616, 2015.

Y. Gheraibia, Méthode hybride pour la prédiction des structures secondaires des protéines, 2012.

A. Ghram, Rapport annuel d'activités du Laboratoire de Pathologie Animale, Rapport annuel d'activités de l'Institut Pasteur de, pp.199-201, 2010.

J. Giacomotto and L. Segalat, High-throughput screening and small animal models, where are we? British journal of pharmacology, vol.160, pp.204-220, 2010.

C. Gitao, C. Mbindyo, R. Omani, and V. Chemweno, Review of Sheep Pox Disease in Sheep, J Vet Med Res, vol.4, issue.1, p.1068, 2017.

J. W. Golden, M. D. Josleyn, and J. W. Hooper, Targeting the vaccinia virus L1 protein to the cell surface enhances production of neutralizing antibodies, Vaccine, vol.26, pp.3507-3522, 2008.

S. Gomez-sebastian, J. Lopez-vidal, and J. M. Escribano, Significant productivity improvement of the baculovirus expression vector system by engineering a novel expression cassette, PloS one, vol.9, issue.5, p.96562, 2014.

S. C. Gong, C. F. Lai, and M. Esteban, Vaccinia virus induces cell fusion at acid pH and this activity is mediated by the N-terminus of the 14-kDa virus envelope protein, Virology, vol.178, issue.1, pp.81-91, 1990.

C. M. Gorman, Mammalian cell expression. Current opinion in biotechnology, vol.1, pp.36-47, 1990.

A. Graentzdoerffer and C. Nemetz, Titration of Non-Occluded Baculovirus Using a Cell Viability Assay, BioTechniques, vol.34, pp.260-264, 2003.

B. S. Graham, R. B. Belshe, M. L. Clements, R. Dolin, L. Corey et al., Vaccination of vaccinianaive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network. The Journal of infectious diseases, vol.166, pp.244-52, 1992.

D. W. Grosenbach, S. G. Hansen, and D. E. Hruby, Identification and analysis of vaccinia virus palmitylproteins, Virology, vol.275, issue.1, pp.193-206, 2000.

C. Gubser, S. Hue, P. Kellam, and G. L. Smith, Poxvirus genomes: a phylogenetic analysis, The Journal of general virology, vol.85, pp.105-122, 2004.

M. Y. Gulbahar, W. C. Davis, H. Yuksel, and M. Cabalar, Immunohistochemical evaluation of inflammatory infiltrate in the skin and lung of lambs naturally infected with sheeppox virus. Veterinary pathology, vol.43, pp.67-75, 2006.

A. Haegeman, K. Zro, D. Sammin, F. Vandenbussche, M. M. Ennaji et al., Investigation of a Possible Link between Vaccination and the 2010. Sheep Pox Epizootic in Morocco Transbound Emerg Diseases, 2015.

D. A. Haig, Lumpy skin disease, Bull EpizootDisAfr, vol.5, pp.421-451, 1957.

H. Haj-ammar, H. Kilani, B. Hamouda, W. Lazghab, A. Jemli et al., Bulletin des Services Vétérinaires -Numéro spécial -Dermatose nodulaire Contagieuse, 2016.

K. Hakola, P. Van-der-boogaart, J. Mulders, R. De-leeuw, W. Schoonen et al., Recombinant rat follicle-stimulating hormone; production by Chinese hamster ovary cells, purification and functional characterization, Molecular and cellular endocrinology, vol.127, issue.1, pp.59-69, 1997.

J. H. Han, S. Batey, A. A. Nickson, S. A. Teichmann, and J. Clarke, The folding and evolution of multidomain proteins, Nature reviews Molecular cell biology, vol.8, issue.4, pp.319-349, 2007.

, Handistatus, 2016.

M. T. Harte, I. R. Haga, G. Maloney, P. Gray, P. C. Reading et al., The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense. The Journal of experimental medicine, vol.197, pp.343-51, 2003.

Y. He, Y. Wang, E. B. Struble, P. Zhang, S. Chowdhury et al., Epitope mapping by random peptide phage display reveals essential residues for vaccinia extracellular enveloped virion spread, Virology journal, vol.9, p.217, 2012.

K. L. Hefferon, A. G. Oomens, S. A. Monsma, C. M. Finnerty, and G. W. Blissard, Host cell receptor binding by baculovirus GP64 and kinetics of virion entry, Virology, vol.258, issue.2, pp.455-68, 1999.

H. G. Heine, M. P. Stevens, A. J. Foord, and D. B. Boyle, A capripoxvirus detection PCR and antibody ELISA based on the major antigen P32, the homolog of the vaccinia virus H3L gene, Journal of immunological methods, vol.227, issue.1-2, pp.187-96, 1999.

M. O. Hengartner, The biochemistry of apoptosis, Nature, vol.407, issue.6805, pp.770-776, 2000.

J. Hennig, I. Wang, M. Sonntag, F. Gabel, and M. Sattler, Combining NMR and small angle X-ray and neutron scattering in the structural analysis of a ternary protein-RNA complex, Journal of biomolecular NMR, vol.56, issue.1, pp.17-30, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01326133

A. Hentzen, Report to South African Veterinary Semen and Embryo Group of the South African Veterinary Association, 2000.

J. M. Heraud, Y. Edghill-smith, V. Ayala, I. Kalisz, J. Parrino et al., Subunit recombinant vaccine protects against monkeypox, Journal of immunology, vol.177, issue.4, pp.2552-64, 1950.

E. Herrera, M. M. Lorenzo, R. Blasco, and S. N. Isaacs, Functional analysis of vaccinia virus B5R protein: essential role in virus envelopment is independent of a large portion of the extracellular domain, Journal of virology, vol.72, issue.1, pp.294-302, 1998.

A. Hildebrand, M. Remmert, A. Biegert, and J. Soding, Fast and accurate automatic structure prediction with HHpred, Proteins, vol.77, issue.9, pp.128-160, 2009.

R. B. Hitchman, E. Locanto, R. D. Possee, and L. A. King, Optimizing the baculovirus expression vector system, Methods, vol.55, issue.1, pp.52-59, 2011.

Y. Ho, J. C. Hsiao, M. H. Yang, C. S. Chung, Y. C. Peng et al., The oligomeric structure of vaccinia viral envelope protein A27L is essential for binding to heparin and heparan sulfates on cell surfaces: a structural and functional approach using site-specific mutagenesis, Journal of molecular biology, vol.349, issue.5, pp.1060-71, 2005.

J. A. Hogsette, J. P. Ruff, and C. J. Jones, Stable fly biology and control in Northwest Florida, J Agric Entomol, vol.4, issue.1, pp.1-11, 1987.

M. Hollinshead, G. Rodger, H. Van-eijl, M. Law, R. Hollinshead et al., Vaccinia virus utilizes microtubules for movement to the cell surface, The Journal of cell biology, vol.154, issue.2, pp.389-402, 2001.

J. A. Holowczak, Uncoating of poxviruses. I. Detection and characterization of subviral particles in the uncoating process, Virology, vol.50, issue.1, pp.216-248, 1972.

. E. Hood, Fromgreenplants to industrial enzymes, EnzymeMicrob Technol, vol.30, pp.279-83, 2002.

J. W. Hooper, D. M. Custer, and E. Thompson, Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates, Virology, vol.306, issue.1, pp.181-95, 2003.

J. W. Hooper, E. Thompson, C. Wilhelmsen, M. Zimmerman, M. A. Ichou et al., Smallpox DNA vaccine protects nonhuman primates against lethal monkeypox, Journal of virology, vol.78, issue.9, pp.4433-4476, 2004.

M. Hosamani, B. Mondal, P. A. Tembhurne, S. K. Bandyopadhyay, R. K. Singh et al., Differentiation of sheep pox and goat poxviruses by sequence analysis and PCR-RFLP of P32 gene, Virus genes, vol.29, issue.1, pp.73-80, 2004.

A. R. Howard, T. G. Senkevich, and B. Moss, Vaccinia virus A26 and A27 proteins form a stable complex tethered to mature virions by association with the A17 transmembrane protein, Journal of virology, vol.82, issue.24, pp.12384-91, 2008.

J. C. Hsiao, C. S. Chung, and W. Chang, Vaccinia virus envelope D8L protein binds to cell surface chondroitin sulfate and mediates the adsorption of intracellular mature virions to cells, Journal of virology, vol.73, issue.10, pp.8750-61, 1999.

F. Q. Hu and D. J. Pickup, Transcription of the terminal loop region of vaccinia virus DNA is initiated from the telomere sequences directing DNA resolution, Virology, vol.181, issue.2, pp.716-736, 1991.

F. Q. Hu, C. A. Smith, and D. J. Pickup, Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor, Virology, vol.204, issue.1, pp.343-56, 1994.

K. Hu, Vectorology and factor delivery in induced pluripotent stem cell reprogramming. Stem cells and development, vol.23, pp.1301-1316, 2014.

Q. Hu, R. J. Noll, H. Li, A. Makarov, M. Hardman et al., The Orbitrap: a new mass spectrometer, Journal of mass spectrometry : JMS, vol.40, issue.4, pp.430-473, 2005.

G. M. Huang and C. K. Wei, Reports on misbirth of pregnant goats after live attenuated goatpox vaccinations, Guangxi Journal of Husbandry and Veterinary Medicine, vol.20, pp.214-219, 2004.

L. J. Hughes, J. Goldstein, J. Pohl, J. W. Hooper, L. Pitts et al., A highly specific monoclonal antibody against monkeypox virus detects the heparin binding domain of A27, Virology, pp.264-73, 2014.

Y. Ichihashi, S. Matsumoto, and S. Dales, Biogenesis of poxviruses: role of A-type inclusions and host cell membranes in virus dissemination, Virology, vol.46, issue.3, pp.507-539, 1971.

Y. Ichihashi and M. Oie, Neutralizing epitope on penetration protein of vaccinia virus, Virology, vol.220, issue.2, pp.491-495, 1996.

Y. Ichihashi, T. Takahashi, and M. Oie, Identification of a vaccinia virus penetration protein, Virology, vol.202, issue.2, pp.834-877, 1994.

W. Ijkel, R. J. Lebbink, M. L. Op-den-brouw, R. W. Goldbach, J. M. Vlak et al., Identification of a novel occlusion derived virus-specific protein in Spodoptera exigua multicapsid nucleopolyhedrovirus, Virology, vol.284, issue.2, pp.170-81, 2001.

L. Ikonomou, Y. J. Schneider, and S. N. Agathos, Insect cell culture for industrial production of recombinant proteins, Applied microbiology and biotechnology, vol.62, issue.1, pp.1-20, 2003.

A. B. Inceoglu, S. G. Kamita, and B. D. Hammock, Genetically modified baculoviruses: a historical overview and future outlook, Advances in virus research, vol.68, pp.323-60, 2006.

D. C. Ireland and Y. S. Binepal, Improved detection of capripoxvirus in biopsy samples by PCR, Journal of virological methods, vol.74, issue.1, pp.1-7, 1998.

P. C. Irons, E. S. Tuppurainen, and E. H. Venter, Excretion of lumpy skin disease virus in bull semen, Theriogenology, vol.63, issue.5, pp.1290-1297, 2005.

S. N. Isaacs, E. J. Wolffe, L. G. Payne, and B. Moss, Characterization of a vaccinia virus-encoded 42-kilodalton class I membrane glycoprotein component of the extracellular virus envelope, Journal of virology, vol.66, issue.12, pp.7217-7241, 1992.

E. C. Jensen, The basics of western blotting, Anatomical record, vol.295, issue.3, pp.369-71, 2007.

B. Jia and J. Co, High-throughput recombinant protein expression in Escherichia coli: current status and future perspectives, Open biology, vol.6, issue.8, 2016.

J. B. Johnston, J. W. Barrett, S. H. Nazarian, M. Goodwin, D. Ricciuto et al., A poxvirusencoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection, Immunity, vol.23, issue.6, pp.587-98, 2005.

J. B. Johnston and G. Mcfadden, Technical knockout: understanding poxvirus pathogenesis by selectively deleting viral immunomodulatory genes, Cellular microbiology, vol.6, issue.8, pp.695-705, 2004.

S. Jonic, Cryo-electron Microscopy Analysis of Structurally Heterogeneous Macromolecular Complexes. Computational and structural biotechnology journal, vol.14, pp.385-90, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01383194

B. Joseph, S. Pichaimuthu, S. Srimeenakshi, M. Murthy, K. Selvakumar et al., An overview of the parameters for recombinant protein expression in Escherichia coli, J Cell Sci Ther, 2005.

S. A. Kaba, A. M. Salcedo, P. O. Wafula, J. M. Vlak, and M. M. Van-oers, Development of a chitinase and vcathepsin negative bacmid for improved integrity of secreted recombinant proteins, Journal of virological methods, vol.122, issue.1, pp.113-121, 2004.

T. Kaever, M. H. Matho, X. Meng, L. Crickard, A. Schlossman et al., Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox, Journal of virology, vol.90, issue.9, pp.4334-4379, 2016.

T. Kaever, X. Meng, M. H. Matho, A. Schlossman, S. Li et al., Potent neutralization of vaccinia virus by divergent murine antibodies targeting a common site of vulnerability in L1 protein, Journal of virology, vol.88, issue.19, pp.11339-55, 2014.

E. Kahana-sutin, E. Klement, I. Lensky, and Y. Gottlieb, High relative abundance of the stable fly Stomoxys calcitrans is associated with lumpy skin disease outbreaks in Israeli dairy farms. Medical and veterinary entomology, vol.31, pp.150-60, 2017.

S. Kalinin, T. Peulen, S. Sindbert, P. J. Rothwell, S. Berger et al., A toolkit and benchmark study for FRET-restrained high-precision structural modeling, Nature methods, vol.9, issue.12, pp.1218-1243, 2012.

L. Kall, A. Krogh, and E. L. Sonnhammer, Advantages of combined transmembrane topology and signal peptide prediction--the Phobius web server. Nucleic acids research, Web Server issue, vol.35, pp.429-461, 2007.

P. D. Kara, C. L. Afonso, D. B. Wallace, G. F. Kutish, C. Abolnik et al., Comparative sequence analysis of the South African vaccine strain and two virulent field isolates of Lumpy skin disease virus, Archives of virology, vol.148, issue.7, pp.1335-56, 2003.

M. Kardjadj, Capripoxviruses: Transboundary Animal Diseases of Domestic Ruminants, Ann Virol Res, vol.2, issue.3, p.1024, 2016.

G. C. Katsafanas and B. Moss, Colocalization of transcription and translation within cytoplasmic poxvirus factories coordinates viral expression and subjugates host functions, Cell host & microbe, vol.2, issue.4, pp.221-229, 2007.

E. Katz, B. M. Ward, A. S. Weisberg, and B. Moss, Mutations in the vaccinia virus A33R and B5R envelope proteins that enhance release of extracellular virions and eliminate formation of actin-containing microvilli without preventing tyrosine phosphorylation of the A36R protein, Journal of virology, vol.77, issue.22, pp.12266-75, 2003.

M. Kearse, R. Moir, A. Wilson, S. Stones-havas, M. Cheung et al., Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data, Bioinformatics, vol.28, issue.12, pp.1647-1656, 2012.

L. A. Kelley, S. Mezulis, C. M. Yates, M. N. Wass, and M. J. Sternberg, The Phyre2 web portal for protein modeling, prediction and analysis, Nature protocols, vol.10, issue.6, pp.845-58, 2015.

J. S. Kennedy, M. Gurwith, C. L. Dekker, S. E. Frey, K. M. Edwards et al., Safety and immunogenicity of LC16m8, an attenuated smallpox vaccine in vaccinia-naive adults. The Journal of infectious diseases, vol.204, pp.1395-402, 2011.

K. H. Khan, Gene expression in Mammalian cells and its applications, vol.3, pp.257-63, 2013.

M. Kidokoro, M. Tashiro, and H. Shida, Genetically stable and fully effective smallpox vaccine strain constructed from highly attenuated vaccinia LC16m8, Proceedings of the National Academy of Sciences of the United States of America, vol.102, issue.11, pp.4152-4159, 2005.

F. Kiefer, K. Arnold, M. Kunzli, L. Bordoli, and T. Schwede, The SWISS-MODEL Repository and associated resources, Nucleic acids research, vol.37, pp.387-92, 2009.

D. W. Kim, T. Uetsuki, Y. Kaziro, N. Yamaguchi, and S. Sugano, Use of the human elongation factor 1 alpha promoter as a versatile and efficient expression system, Gene, vol.91, issue.2, pp.217-240, 1990.

M. Kitchen, H. Müller, A. Zobl, A. Windisch, N. Romani et al., Orf virus infection in a hunter presumably transmitted by game in Western Austria, Acta Derm Venereol, vol.94, pp.212-216, 2014.

P. Kitching, Progress towards sheep and goat pox vaccines, Vaccine, vol.1, issue.1, pp.4-9, 1983.

R. P. Kitching, The control of sheep and goat pox, Rev Sci Tech Off Int Epizoot, vol.5, pp.503-514, 1986.

R. P. Kitching, Passive protection of sheep against capripoxvirus, vol.41, pp.247-50, 1986.

R. P. Kitching, Sheep pox and goat pox, Infectious Diseases of Livestock, pp.2-12

). Edn and . Capetown, , pp.1277-81, 2004.

R. P. Kitching and V. M. Carn, Office International des Epizooties Manual of Diagnostic Tests and Vaccines for Terrestrial Animals (mammals, birds and bees) OIE, pp.1058-68, 2008.

R. P. Kitching, J. M. Hammond, and D. N. Black, Studies on the major common precipitating antigen of capripoxvirus. The Journal of general virology, vol.67, pp.139-187, 1986.

R. P. Kitching, J. M. Hammond, and W. P. Taylor, A single vaccine for the control of capripox infection in sheep and goats. Research in veterinary science, vol.42, pp.53-60, 1987.

R. P. Kitching and P. S. Mellor, Insect transmission of capripoxvirus, vol.40, pp.255-263, 1986.

R. P. Kitching and C. Smale, Comparison of the external dimensions of capripoxvirus isolates. Research in veterinary science, vol.41, pp.425-432, 1986.

R. P. Kitching and W. P. Taylor, Clinical and antigenic relationship between isolates of sheep and goat pox viruses. Tropical animal health and production, vol.17, pp.64-74, 1985.

R. P. Kitching and W. P. Taylor, Research in veterinary science, vol.39, pp.196-205, 1985.

Z. Klausner, E. Fattal, and E. Klement, Using Synoptic Systems' Typical Wind Trajectories for the Analysis of Potential Atmospheric Long-Distance Dispersal of Lumpy Skin Disease Virus. Transboundary and emerging diseases, 2015.

G. Kochan, D. Escors, J. M. Gonzalez, J. M. Casasnovas, and M. Esteban, Membrane cell fusion activity of the vaccinia virus A17-A27 protein complex, Cellular microbiology, vol.10, issue.1, pp.149-64, 2008.

T. A. Kost and C. W. Kemp, Fundamentals of Baculovirus Expression and Applications. Advances in experimental medicine and biology, vol.896, pp.187-97, 2016.

V. Koya, M. Moayeri, S. H. Leppla, and H. Daniell, Plant-based vaccine: mice immunized with chloroplast-derived anthrax protective antigen survive anthrax lethal toxin challenge, Infection and immunity, vol.73, issue.12, pp.8266-74, 2005.

C. D. Krause and S. Pestka, Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives, Pharmacology & therapeutics, vol.106, issue.3, pp.299-346, 2005.

J. V. Kringelum, C. Lundegaard, O. Lund, and M. Nielsen, Reliable B cell epitope predictions: impacts of method development and improved benchmarking, PLoS computational biology, vol.8, issue.12, p.1002829, 2012.

A. Krogh, B. Larsson, G. Von-heijne, and E. L. Sonnhammer, Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes, Journal of molecular biology, vol.305, issue.3, pp.567-80, 2001.

M. Krupovic, V. Cvirkaite-krupovic, and D. H. Bamford, Protein A33 responsible for antibody-resistant spread of Vaccinia virus is homologous to C-type lectin-like proteins, Virus research, vol.151, issue.1, pp.97-101, 2010.
URL : https://hal.archives-ouvertes.fr/pasteur-01977414

A. Kumar, R. Yogisharadhya, V. Bhanuprakash, G. Venkatesan, and S. B. Shivachandra, Structural analysis and immunogenicity of recombinant major envelope protein (rA27L) of buffalopox virus, a zoonotic Indian vaccinia-like virus, Vaccine, vol.33, issue.41, pp.5396-405, 2015.

B. T. Kurien and R. H. Scofield, Western blotting: an introduction, Methods in molecular biology, vol.1312, pp.17-30, 2015.

C. F. Lai, S. C. Gong, and M. Esteban, The purified 14-kilodalton envelope protein of vaccinia virus produced in Escherichia coli induces virus immunity in animals, Journal of virology, vol.65, issue.10, pp.5631-5636, 1991.

C. F. Lai, S. C. Gong, and M. Esteban, Structural and functional properties of the 14-kDa envelope protein of vaccinia virus synthesized in Escherichia coli, The Journal of biological chemistry, vol.265, issue.36, pp.22174-80, 1990.

C. E. Lamien, L. Goff, C. Silber, R. Wallace, D. B. Gulyaz et al., Use of the Capripoxvirus homologue of Vaccinia virus 30 kDa RNA polymerase subunit (RPO30) gene as a novel diagnostic and genotyping target: development of a classical PCR method to differentiate Goat poxvirus from Sheep poxvirus. Veterinary microbiology, vol.149, pp.30-39, 2011.
URL : https://hal.archives-ouvertes.fr/hal-02651804

C. E. Lamien, M. Lelenta, W. Goger, R. Silber, E. Tuppurainen et al., Real time PCR method for simultaneous detection, quantitation and differentiation of capripoxviruses, Journal of virological methods, vol.171, issue.1, pp.134-174, 2011.

J. E. Larsen, O. Lund, and M. Nielsen, Improved method for predicting linear B-cell epitopes, Immunome research, vol.2, issue.2, 2006.

P. Larsson, M. J. Skwark, B. Wallner, and A. Elofsson, Improved predictions by Pcons.net using multiple templates, Bioinformatics, vol.27, issue.3, pp.426-433, 2011.

M. Law, R. Hollinshead, and G. L. Smith, Antibody-sensitive and antibody-resistant cell-to-cell spread by vaccinia virus: role of the A33R protein in antibody-resistant spread, The Journal of general virology, vol.83, pp.209-231, 2002.

M. Law and G. L. Smith, Antibody neutralization of the extracellular enveloped form of vaccinia virus, Virology, vol.280, issue.1, pp.132-174, 2001.

S. J. Lawrence, K. R. Lottenbach, F. K. Newman, R. M. Buller, C. J. Bellone et al., Antibody responses to vaccinia membrane proteins after smallpox vaccination. The Journal of infectious diseases, vol.196, pp.220-229, 2007.

L. Goff, C. Fakhfakh, A. Chadeyras, E. Aba-adulugba, E. Libeau et al., Host range phylogenetic grouping of capripoxviruses: Genetic typing of CaPVs. In Applications of Gene based Technologies for Improving Animal Production and Health in Developing Countries Edited by HPS Makkar and GJ Viljoen BerlinSpringer, pp.727-760, 2005.

L. Goff, C. Lamien, C. E. Fakhfakh, E. Chadeyras, A. Aba-adulugba et al., Capripoxvirus G-protein-coupled chemokine receptor: a host-range gene suitable for virus animal origin discrimination, The Journal of general virology, vol.90, pp.1967-77, 2009.
URL : https://hal.archives-ouvertes.fr/hal-02666433

J. G. Lees, D. Lee, R. A. Studer, N. L. Dawson, I. Sillitoe et al., Multi-domain annotations for protein sequence and comparative genome analysis, Nucleic acids research, vol.42, pp.240-245, 2014.

P. C. Lefèvre, La variole ovine (clavelée) et la variole caprine, Etudes et synthèses de l'IEMVT Maisons, p.171, 1983.

E. J. Lefkowitz, C. Wang, and C. Upton, Poxviruses: past, present and future, Virus research, vol.117, issue.1, pp.105-123, 2006.

S. F. Li, H. L. Wang, Z. H. Hu, and F. Deng, Genetic modification of baculovirus expression vectors, Virologica Sinica, vol.27, issue.2, pp.71-82, 2012.

P. Liljestrom and H. Garoff, A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/technology (Nature Publishing Company), vol.9, pp.1356-61, 1991.

C. L. Lin, C. S. Chung, H. G. Heine, and W. Chang, Vaccinia virus envelope H3L protein binds to cell surface heparan sulfate and is important for intracellular mature virion morphogenesis and virus infection in vitro and in vivo, Journal of virology, vol.74, issue.7, pp.3353-65, 2000.

T. H. Lin, C. M. Chia, J. C. Hsiao, W. Chang, C. C. Ku et al., Structural analysis of the extracellular domain of vaccinia virus envelope protein, A27L, by NMR and CD spectroscopy, The Journal of biological chemistry, vol.277, issue.23, pp.20949-59, 2002.

F. Liu, X. Wu, L. Li, Z. Liu, and Z. Wang, Use of baculovirus expression system for generation of viruslike particles: successes and challenges. Protein expression and purification, vol.90, pp.104-120, 2013.

B. Lobb and A. C. Doxey, Novel function discovery through sequence and structural data mining. Current opinion in structural biology, vol.38, pp.53-61, 2016.

M. M. Lorenzo, J. M. Sanchez-puig, and R. Blasco, Mutagenesis of the palmitoylation site in vaccinia virus envelope glycoprotein B5. The Journal of general virology, vol.93, pp.733-776, 2012.

J. C. Lubinga, E. S. Tuppurainen, J. A. Coetzer, W. H. Stoltsz, and E. H. Venter, Transovarial passage and transmission of LSDV by Amblyomma hebraeum, Rhipicephalus appendiculatus and Rhipicephalus decoloratus, Experimental & applied acarology, vol.62, issue.1, pp.67-75, 2014.

J. C. Lubinga, E. S. Tuppurainen, W. H. Stoltsz, K. Ebersohn, J. A. Coetzer et al., Detection of lumpy skin disease virus in saliva of ticks fed on lumpy skin disease virus-infected cattle, Experimental & applied acarology, vol.61, issue.1, pp.129-167, 2013.

K. Lundstrom, Alphaviruses in gene therapy, Viruses, vol.7, issue.5, pp.2321-2354, 2015.

S. Lustig, C. Fogg, J. C. Whitbeck, R. J. Eisenberg, G. H. Cohen et al., Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge, Journal of virology, vol.79, issue.21, pp.13454-62, 2005.

S. Lustig, C. Fogg, J. C. Whitbeck, and B. Moss, Synergistic neutralizing activities of antibodies to outer membrane proteins of the two infectious forms of vaccinia virus in the presence of complement, Virology, vol.328, issue.1, pp.30-35, 2004.

S. Macauley-patrick, M. L. Fazenda, B. Mcneil, and L. M. Harvey, Heterologous protein production using the Pichia pastoris expression system, Yeast (Chichester, England), vol.22, issue.4, pp.249-70, 2005.

M. Mackett, G. L. Smith, and B. Moss, Vaccinia virus: a selectable eukaryotic cloning and expression vector, Proceedings of the National Academy of Sciences of the United States of America, vol.79, issue.23, pp.7415-7424, 1982.

M. A. Mahmood, Z. Hesni, and S. Afzal, Preparation of live sheep pox tissue culture vaccine, Pakistan Vet J, vol.8, pp.56-63, 1988.

O. Mangana-vougiouka, P. Markoulatos, G. Koptopoulos, K. Nomikou, N. Bakandritsos et al., Sheep poxvirus identification by PCR in cell cultures, Journal of virological methods, vol.77, issue.1, pp.75-84, 1999.

O. Mangana, C. Kottaridi, and K. Nomikou, The epidemiology of sheep pox in Greece from 1987 to, Rev Sci Tech, vol.27, pp.899-905, 2007.

A. Manz, N. Pamme, and D. Iossifidis, Bioanalytical Chemistry, 2004.

M. Marek, M. M. Van-oers, F. F. Devaraj, J. M. Vlak, and O. W. Merten, Engineering of baculovirus vectors for the manufacture of virion-free biopharmaceuticals, Biotechnology and bioengineering, vol.108, issue.5, pp.1056-67, 2011.

M. Margittai, J. Widengren, E. Schweinberger, G. F. Schroder, S. Felekyan et al., Singlemolecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1, Proceedings of the National Academy of Sciences of the United States of America, vol.100, issue.26, pp.15516-15537, 2003.

P. Markoulatos, O. Mangana-vougiouka, G. Koptopoulos, K. Nomikou, and O. Papadopoulos, Detection of sheep poxvirus in skin biopsy samples by a multiplex polymerase chain reaction, Journal of virological methods, vol.84, issue.2, pp.161-168, 2000.

V. Mateva and S. Stoichev, Adaptation and cultivation of sheep pox virus (strain Perego) in tissue cultures and evaluation of its immunogenic properties, Vet Med Nauki, vol.12, pp.18-23, 1975.

J. Maupetit, Prédiction de la structure des protéines, 2007.

S. Maurer-stroh and F. Eisenhaber, Myristoylation of viral and bacterial proteins, Trends in microbiology, vol.12, issue.4, pp.178-85, 2004.

L. Mccarroll and L. A. King, Stable insect cell cultures for recombinant protein production, Current opinion in biotechnology, vol.8, issue.5, pp.590-594, 1997.

G. Mcfadden, Poxvirus tropism, Nature reviews Microbiology, vol.3, issue.3, pp.201-214, 2005.

L. J. Mcguffin, K. Bryson, and D. T. Jones, The PSIPRED protein structure prediction server, Bioinformatics, vol.16, issue.4, pp.404-409, 2000.

R. L. Mckown and R. A. Teutonico, Transgenic animals for production of proteins, Gen Eng News, vol.19, issue.9, p.60, 1999.

P. S. Mellor, R. P. Kitching, and P. J. Wilkinson, Mechanical transmission of capripoxvirus and African swine fever virus by Stomoxys calcitrans, Res Vet Sci, vol.43, pp.109-121, 1987.

F. J. Mergulhao, D. K. Summers, and G. A. Monteiro, Recombinant protein secretion in Escherichia coli, Biotechnology advances, vol.23, issue.3, pp.177-202, 2005.

C. A. Meseda, J. Campbell, A. Kumar, A. D. Garcia, M. Merchlinsky et al., Effect of the deletion of genes encoding proteins of the extracellular virion form of vaccinia virus on vaccine immunogenicity and protective effectiveness in the mouse model, PloS one, vol.8, issue.6, p.67984, 2013.

F. Messud-petit, J. Gelfi, M. Delverdier, M. F. Amardeilh, R. Py et al., Serp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus, Journal of virology, vol.72, issue.10, pp.7830-7839, 1998.
URL : https://hal.archives-ouvertes.fr/hal-02697357

A. D. Michie, C. A. Orengo, and J. M. Thornton, Analysis of domain structural class using an automated class assignment protocol, Journal of molecular biology, vol.262, issue.2, pp.168-85, 1996.

K. Mirzaie, S. M. Barani, and S. Bokaie, A review of sheep pox and goat pox: perspective of their control and eradication in Iran, J Adv Vet Anim Res, vol.2, pp.373-81, 2015.

S. Mitra and A. Tinku, Data Mining Multimedia, soft computing and bioinformatique, 2003.

B. Mondal, M. Hosamani, T. K. Dutta, S. V. Senthilkumar, R. Rathoreand et al., An outbreak of sheep pox on a sheep breeding farm in Jammu, India. Rev Sci Tech, OIE, vol.23, pp.943-952, 2004.

. Morrow, Improving protein production processes, Gen Eng News, vol.27, issue.5, pp.50-91, 2007.

B. Moss, Poxviridae: the viruses and their replication, Virology Philadelphia, pp.2849-83, 2001.

B. Moss, Poxvirus DNA replication. Cold Spring Harbor perspectives in biology, vol.5, 2013.

B. Moss, Poxvirus membrane biogenesis, Virology, pp.619-645, 2015.

B. Moss, Regulation of orthopoxvirus gene expression. Current topics in microbiology and immunology, vol.163, pp.41-70, 1990.

B. Moss and E. N. Rosenblum, Letter: Protein cleavage and poxvirus morphogenesis: tryptic peptide analysis of core precursors accumulated by blocking assembly with rifampicin, Journal of molecular biology, vol.81, issue.2, pp.267-276, 1973.

K. Mossman, C. Upton, R. M. Buller, and G. Mcfadden, Species specificity of ectromelia virus and vaccinia virus interferon-gamma binding proteins, Virology, vol.208, issue.2, pp.762-771, 1995.

T. Murata, Y. Shinozuka, Y. Obata, and K. K. Yokoyama, Phosphorylation of two eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, Escherichia coli by Jun Nterminal kinase 1, vol.376, pp.115-136, 2008.

F. A. Murphy, E. Gibbs, M. C. Horzinek, M. J. Studdert, and . Poxviridae, , pp.277-91, 1999.

L. Murray, L. Edwards, E. S. Tuppurainen, K. Bachanek-bankowska, C. A. Oura et al., Detection of capripoxvirus DNA using a novel loop-mediated isothermal amplification assay, BMC veterinary research, vol.9, p.90, 2013.

M. Murray, W. B. Martin, and A. Koylu, Experimental sheep pox. A histological and ultrastructural study, vol.15, pp.201-209, 1973.

C. K. Ngichabe, Y. S. Binepal, J. W. Njiru, and V. M. Carn, Evaluation of an immunocapture enzyme-linked immunosorbent assay for detection of capripoxviruses. The Veterinary record, vol.145, pp.231-233, 1999.

H. Nielsen, J. Engelbrecht, S. Brunak, and G. Von-heijne, Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites, Protein engineering, vol.10, issue.1, pp.1-6, 1997.

T. Notomi, H. Okayama, H. Masubuchi, T. Yonekawa, K. Watanabe et al., Loop-mediated isothermal amplification of DNA, Nucleic acids research, vol.28, issue.12, p.63, 2000.

J. Nuttall, A. Vitale, and L. Frigerio, C-terminal extension of phaseolin with a short methionine-rich sequence can inhibit trimerisation and result in high instability, Plant molecular biology, vol.51, issue.6, pp.885-94, 2003.

C. J. O'connell, D. T. Karzon, A. L. Barron, M. E. Plaut, and V. M. Ali, Progressive vaccinia with normal antibodies. A case possibly due to deficient cellular immunity, Annals of internal medicine, vol.60, pp.282-291, 1964.

C. Odissev, C. H. Sghaier, S. H. Bejaoui, and L. La-clavelée, Synthèse Bibliographique et Situation Actuelle en Tunisie, Bull Epid Inf Vet, vol.8, 1995.

. Oie, Lumpy skin disease.In:Manual of Diagnostic Tests and Vaccines for Terrestrial Animals

, Office International des Epizooties,World Organization for Animal Health Paris, pp.1-13, 2010.

. Oie, Manual of diagnostic tests and vaccines for terrestrial animals, OIE Part, vol.2, pp.1-17, 2004.

T. Okamoto, S. Campbell, N. Mehta, J. Thibault, P. M. Colman et al., Sheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins, Journal of virology, vol.86, issue.21, pp.11501-11512, 2012.

A. G. Oomens and G. W. Blissard, Requirement for GP64 to drive efficient budding of Autographa californica multicapsid nucleopolyhedrovirus, Virology, vol.254, issue.2, pp.297-314, 1999.

C. A. Orengo, F. M. Pearl, J. E. Bray, A. E. Todd, A. C. Martin et al., The CATH Database provides insights into protein structure/function relationships, Nucleic acids research, vol.27, issue.1, pp.275-284, 1999.

E. S. Orlova, A. V. Shcherbakova, V. I. Diev, and V. M. Zakharov, Differentiation of capripoxvirus species and strains by polymerase chain reaction, Molekuliarnaia biologiia, vol.40, issue.1, pp.158-64, 2006.

J. Osz-papai, L. Radu, W. Abdulrahman, I. Kolb-cheynel, N. Troffer-charlier et al., Insect cells-baculovirus system for the production of difficult to express proteins, Methods in molecular biology, vol.1258, pp.181-205, 2015.

R. Owczarzy, A. V. Tataurov, Y. Wu, J. A. Manthey, K. A. Mcquisten et al., IDT SciTools: a suite for analysis and design of nucleic acid oligomers, Nucleic acids research, vol.36, pp.163-172, 2008.

L. R. Paborsky, B. M. Fendly, K. L. Fisher, R. M. Lawn, B. J. Marks et al., Mammalian cell transient expression of tissue factor for the production of antigen, Protein engineering, vol.3, issue.6, pp.547-53, 1990.

A. Pacha-bey, Décret du 1er Mai 1931. Archives de l, Institut Pasteur de Tunis, vol.3, pp.243-247, 1931.

B. Pang, Y. Zhu, L. Lu, F. Gu, and H. Chen, The Applications and Features of Liquid Chromatography-Mass Spectrometry in the Analysis of Traditional Chinese Medicine. Evidence-based complementary and alternative medicine : eCAM, p.3837270, 2016.

N. Paran, S. Lustig, A. Zvi, N. Erez, T. Israely et al., Active vaccination with vaccinia virus A33 protects mice against lethal vaccinia and ectromelia viruses but not against cowpoxvirus; elucidation of the specific adaptive immune response, Virology journal, vol.10, p.229, 2013.

J. H. Parham, T. Kost, and J. T. Hutchins, Effects of pCIneo and pCEP4 expression vectors on transient and stable protein production in human and simian cell lines, Cytotechnology, vol.35, issue.3, pp.181-188, 2001.

J. M. Parker, D. Guo, and R. S. Hodges, New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites, Biochemistry, vol.25, pp.5425-5457, 1986.

B. L. Parsons and D. J. Pickup, Transcription of orthopoxvirus telomeres at late times during infection, Virology, vol.175, issue.1, pp.69-80, 1990.

P. P. Pastoret, Emerging diseases, zoonoses and vaccines to control them, Vaccine, vol.27, pp.6435-6443, 2009.

L. G. Payne, Significance of extracellular enveloped virus in the in vitro and in vivo dissemination of vaccinia. The Journal of general virology, vol.50, pp.89-100, 1980.

V. M. Penkova, F. A. Jassim, J. R. Thompson, and T. M. Ai-doori, The propagation of an attenuated sheep pox virus and its use as a vaccine Bull, Off Int Epizoot, issue.329, p.81, 1974.

B. Perdiguero and R. Blasco, Interaction between vaccinia virus extracellular virus envelope A33 and B5 glycoproteins, Journal of virology, vol.80, issue.17, pp.8763-77, 2006.

J. Perino, N. M. Thielens, E. Crouch, D. Spehner, J. M. Crance et al., Protective effect of surfactant protein d in pulmonary vaccinia virus infection: implication of A27 viral protein, Viruses, vol.5, issue.3, pp.928-53, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01322444

A. Perrin, A. E. Breard, E. Sailleau, C. Prome, S. Grillet et al., Recombinant capripoxviruses expressing proteins of bluetongue virus: evaluation of immune responses and protection in small ruminants, Vaccine, vol.25, pp.6774-83, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02667743

B. Petersen, T. N. Petersen, P. Andersen, M. Nielsen, and C. Lundegaard, A generic method for assignment of reliability scores applied to solvent accessibility predictions, BMC structural biology, vol.9, p.51, 2009.

D. J. Pickup, D. Bastia, H. O. Stone, and W. K. Joklik, Sequence of terminal regions of cowpox virus DNA: arrangement of repeated and unique sequence elements, Proceedings of the National Academy of Sciences of the United States of America, vol.79, issue.23, pp.7112-7118, 1982.

U. Pieper, B. M. Webb, D. T. Barkan, D. Schneidman-duhovny, A. Schlessinger et al.,

, ModBase, a database of annotated comparative protein structure models, and associated resources, Nucleic acids research, vol.39, pp.465-74, 2011.

W. Plowright and R. D. Ferris, The growth and cytopathogenicity of sheep-pox virus in tissue cultures, British journal of experimental pathology, vol.39, issue.4, pp.424-459, 1958.

R. D. Possee and L. A. King, Baculovirus Transfer Vectors, Methods in molecular biology, vol.1350, pp.51-71, 2016.

P. Precausta, F. Kato, and G. Vellut, A new freeze-dried living virus vaccine against sheep-pox

, Comp Immun Microbio/Infect Dis, vol.1, p.305, 1979.

. Promed, Europe (09): Romania, preparedness, prevention

L. Prozesky and B. J. Barnard, A study of the pathology of lumpy skin disease in cattle. The Onderstepoort journal of veterinary research, vol.49, pp.167-75, 1982.

D. J. Pulford, A. Gates, S. H. Bridge, J. H. Robinson, and D. Ulaeto, Differential efficacy of vaccinia virus envelope proteins administered by DNA immunisation in protection of BALB/c mice from a lethal intranasal poxvirus challenge, Vaccine, vol.22, pp.3358-66, 2004.

M. M. Putz, C. M. Midgley, M. Law, and G. L. Smith, Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination, Nature medicine, vol.12, issue.11, pp.1310-1315, 2006.

S. Raman, R. Vernon, J. Thompson, M. Tyka, R. Sadreyev et al., Structure prediction for CASP8 with all-atom refinement using Rosetta, Proteins, vol.77, issue.9, pp.89-99, 2009.

J. Ramisse, J. Asso, A. Hassani, O. Anane, and J. Jemli, Culture du virus claveleux sur cellules : Application à la vaccination et au contrôle de l'immunité, Rev Elev Méd Vét PaysTrop, vol.31, pp.11-20, 1978.

R. Hah, Development of an attenuated live virus vaccine against sheep pox, M Arch Inst RazL, pp.20-77, 1968.

B. T. Rao, H. J. Das, R. D. Sharma, and S. Singh, Some observations on an outbreak of sheep pox in sheep in East Godavari District, Andhra Pradesh. Livest Advisor, pp.3-6, 1994.

T. V. Rao and S. K. Bandyopadhyay, Animal health research reviews / Conference of Research Workers in Animal Diseases, vol.1, pp.127-163, 2000.

T. V. Rao, B. S. Negi, P. Dhar, and D. Asgola, Evaluation of latex agglutination test for rapid detection of goat poxvirus antigen and antibodies, Acta virologica, vol.40, issue.2, pp.95-102, 1996.

M. P. Ravanello, C. A. Franke, and D. E. Hruby, An NH2-terminal peptide from the vaccinia virus L1R protein directs the myristylation and virion envelope localization of a heterologous fusion protein, The Journal of biological chemistry, vol.268, issue.10, pp.7585-93, 1993.

M. P. Ravanello and D. E. Hruby, Characterization of the vaccinia virus L1R myristylprotein as a component of the intracellular virion envelope. The Journal of general virology, vol.75, pp.1479-83, 1994.

M. P. Ravanello and D. E. Hruby, Conditional lethal expression of the vaccinia virus L1R myristylated protein reveals a role in virion assembly, Journal of virology, vol.68, issue.10, pp.6401-6411, 1994.

G. A. Reeves, T. J. Dallman, O. C. Redfern, A. Akpor, and C. A. Orengo, Structural diversity of domain superfamilies in the CATH database, Journal of molecular biology, vol.360, issue.3, pp.725-766, 2006.

, REMESA

M. M. Rigano, C. Manna, A. Giulini, E. Pedrazzini, M. Capobianchi et al., Transgenic chloroplasts are efficient sites for high-yield production of the vaccinia virus envelope protein A27L in plant cellsdagger, Plant biotechnology journal, vol.7, issue.6, pp.577-91, 2009.

D. Robert and B. Vian, Elément de biologie cellulaire, 2008.

K. L. Roberts, A. Breiman, G. C. Carter, H. A. Ewles, M. Hollinshead et al., Acidic residues in the membrane-proximal stalk region of vaccinia virus protein B5 are required for glycosaminoglycanmediated disruption of the extracellular enveloped virus outer membrane, The Journal of general virology, vol.90, pp.1582-91, 2009.

D. B. Roche, M. T. Buenavista, S. J. Tetchner, and L. J. Mcguffin, The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction, Nucleic acids research, vol.39, pp.171-177, 2011.

J. F. Rodriguez and M. Esteban, Mapping and nucleotide sequence of the vaccinia virus gene that encodes a 14-kilodalton fusion protein, Journal of virology, vol.61, issue.11, pp.3550-3554, 1987.

J. F. Rodriguez, R. Janeczko, and M. Esteban, Isolation and characterization of neutralizing monoclonal antibodies to vaccinia virus, Journal of virology, vol.56, issue.2, pp.482-490, 1985.

J. F. Rodriguez and G. L. Smith, IPTG-dependent vaccinia virus: identification of a virus protein enabling virion envelopment by Golgi membrane and egress, Nucleic acids research, vol.18, issue.18, pp.5347-51, 1990.

A. Roldao, R. Oliveira, M. J. Carrondo, and P. M. Alves, Error assessment in recombinant baculovirus titration: evaluation of different methods, Journal of virological methods, vol.159, issue.1, pp.69-80, 2009.

C. H. Romero, T. Barrett, R. W. Chamberlain, R. P. Kitching, M. Fleming et al., Recombinant capripoxvirus expressing the hemagglutinin protein gene of rinderpest virus: protection of cattle against rinderpest and lumpy skin disease viruses, Virology, vol.204, issue.1, pp.425-434, 1994.

C. H. Romero, T. Barrett, S. A. Evans, R. P. Kitching, P. D. Gershon et al., Single capripoxvirus recombinant vaccine for the protection of cattle against rinderpest and lumpy skin disease, Vaccine, vol.11, issue.7, pp.737-779, 1993.

C. H. Romero, T. Barrett, R. P. Kitching, V. M. Carn, and D. N. Black, Protection of cattle against rinderpest and lumpy skin disease with a recombinant capripoxvirus expressing the fusion protein gene of rinderpest virus. The Veterinary record, vol.135, pp.152-156, 1994.

P. Rondia, Aperçu de l'élevage ovin en Afrique du Nord. Filière Ovine et Caprine, vol.18, pp.11-15, 2006.

R. L. Roper, L. G. Payne, and B. Moss, Extracellular vaccinia virus envelope glycoprotein encoded by the A33R gene, Journal of virology, vol.70, issue.6, pp.3753-62, 1996.

R. L. Roper, E. J. Wolffe, A. Weisberg, and B. Moss, The envelope protein encoded by the A33R gene is required for formation of actin-containing microvilli and efficient cell-to-cell spread of vaccinia virus, Journal of virology, vol.72, issue.5, pp.4192-204, 1998.

R. Rosales, G. Sutter, and B. Moss, A cellular factor is required for transcription of vaccinia viral intermediate-stage genes, Proceedings of the National Academy of Sciences of the United States of America, vol.91, issue.9, pp.3794-3802, 1994.

A. Roulston, R. C. Marcellus, and P. E. Branton, Viruses and apoptosis. Annual review of microbiology, vol.53, pp.577-628, 1999.

P. K. Roychoudhury, S. S. Khaparde, B. Mattiasson, and A. Kumar, Synthesis, regulation and production of urokinase using mammalian cell culture: a comprehensive review, Biotechnology advances, vol.24, issue.5, pp.514-542, 2006.

I. Ruczinski, Protein Structure Prediction : Secondary Structure, 2008.

R. Rudraraju and A. J. Ramsay, Single-shot immunization with recombinant adenovirus encoding vaccinia virus glycoprotein A27L is protective against a virulent respiratory poxvirus infection, Vaccine, vol.28, issue.31, pp.4997-5004, 2010.

B. Rusche, The 3Rs and animal welfare -conflict or the way forward?, Altex, vol.20, issue.1, pp.63-76, 2003.

D. Russel, K. Lasker, B. Webb, J. Velazquez-muriel, E. Tjioe et al., Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies, PLoS biology, vol.10, issue.1, p.1001244, 2012.

H. Rziha, M. Henkel, R. Cottone, B. Bauer, U. Auge et al., Generation of recombinant parapoxviruses: non-essential genes suitable for insertion and expression of foreign genes, Journal of biotechnology, vol.83, issue.1-2, pp.137-182, 2000.

M. Saijo, Y. Ami, Y. Suzaki, N. Nagata, N. Iwata et al., LC16m8, a highly attenuated vaccinia virus vaccine lacking expression of the membrane protein B5R, protects monkeys from monkeypox, Journal of virology, vol.80, issue.11, pp.5179-88, 2006.

R. K. Saiki, D. H. Gelfand, S. Stoffel, S. J. Scharf, R. Higuchi et al., Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase, Science

A. Salem, E. Bouhsira, E. Liénard, B. Melou, A. Jacquiet et al., Susceptibility of Two European strains of Stomoxys calcitrans (L.) to Cypermethrin, Deltamethrin, Fenvalerate, cyhalothrin, Permethrin and Phoxim, Intern J Appl Res Vet Med, vol.10, issue.3, pp.249-57, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02645910

U. Samanta, R. P. Bahadur, and P. Chakrabarti, Quantifying the accessible surface area of protein residues in their local environment, Protein engineering, vol.15, issue.8, pp.659-67, 2002.

C. M. Sanderson, M. Hollinshead, and G. L. Smith, The vaccinia virus A27L protein is needed for the microtubule-dependent transport of intracellular mature virus particles, The Journal of general virology, vol.81, pp.47-58, 2000.

R. Santhamani, G. Venkatesan, S. K. Minhas, S. B. Shivachandra, D. Muthuchelvan et al., Detection and characterization of atypical capripoxviruses among small ruminants in India, Virus genes, vol.51, pp.33-41, 2015.

S. Schlesinger, Alphavirus vectors: development and potential therapeutic applications, Expert opinion on biological therapy, vol.1, issue.2, pp.177-91, 2001.

M. Schmelz, B. Sodeik, M. Ericsson, E. J. Wolffe, H. Shida et al., Assembly of vaccinia virus: the second wrapping cisterna is derived from the trans Golgi network, Journal of virology, vol.68, issue.1, pp.130-177, 1994.

F. R. Schmidt, Recombinant expression systems in the pharmaceutical industry, Applied microbiology and biotechnology, vol.65, issue.4, pp.363-72, 2004.

T. Schwede, Protein modeling: what happened to the "protein structure gap, Structure, vol.21, issue.9, pp.1531-1571, 1993.

B. T. Seet, J. B. Johnston, C. R. Brunetti, J. W. Barrett, H. Everett et al., Poxviruses and immune evasion, Annual review of immunology, vol.21, pp.377-423, 2003.

T. G. Senkevich, B. M. Ward, and B. Moss, Vaccinia virus entry into cells is dependent on a virion surface protein encoded by the A28L gene, Journal of virology, vol.78, issue.5, pp.2357-66, 2004.

B. Sharma, B. S. Negi, A. B. Pandey, S. K. Bandyopadhyay, H. Shankar et al., Detection of goat pox antigen and antibody by the counter immunoelectrophoresis test. Tropical animal health and production, vol.20, pp.109-122, 1988.

S. N. Shchelkunov, A. V. Totmenin, I. V. Babkin, P. F. Safronov, O. I. Ryazankina et al., Human monkeypox and smallpox viruses: genomic comparison, FEBS letters, vol.509, issue.1, pp.66-70, 2001.

Y. Shen, R. Vernon, D. Baker, and A. Bax, De novo protein structure generation from incomplete chemical shift assignments, Journal of biomolecular NMR, vol.43, issue.2, pp.63-78, 2009.

P. C. Shih, M. S. Yang, S. C. Lin, Y. Ho, J. C. Hsiao et al., A turn-like structure "KKPE" segment mediates the specific binding of viral protein A27 to heparin and heparan sulfate on cell surfaces, The Journal of biological chemistry, vol.284, issue.52, pp.36535-36581, 2009.

K. Shinoda, L. S. Wyatt, K. R. Irvine, and B. Moss, Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization, Virology journal, vol.6, p.28, 2009.

I. P. Singh, . Pr, and R. N. Srivastava, Sheep pox: a review, Vet Bull, vol.49, issue.3, pp.145-54, 1979.

R. K. Singh, V. Balamurugan, M. Hosamani, U. K. De, B. M. Chandra et al., B5r gene based sequence analysis of Indian buffalopox virus isolates in relation to other orthopoxviruses, Acta virologica, vol.51, issue.1, pp.47-50, 2007.

H. Skovgard and G. Nachman, Biological control of house flies Musca domestica and stable flies Stomoxys calcitrans(Diptera: Muscidae) by means of inundative releases of Spalangia cameroni(Hymenoptera: Pteromalidae), Bulletin of entomological research, vol.94, issue.6, pp.555-67, 2004.

J. C. Small and H. C. Ertl, Viruses -from pathogens to vaccine carriers. Current opinion in virology, vol.1, pp.241-246, 2011.

G. E. Smith, M. D. Summers, and M. J. Fraser, Production of human beta interferon in insect cells infected with a baculovirus expression vector, Molecular and cellular biology, vol.3, issue.12, pp.2156-65, 1983.

G. L. Smith and M. Law, The exit of vaccinia virus from infected cells, Virus research, vol.106, issue.2, pp.189-97, 2004.

G. L. Smith, A. Vanderplasschen, and M. Law, The formation and function of extracellular enveloped vaccinia virus. The Journal of general virology, vol.83, pp.2915-2946, 2002.

M. S. Smyth and J. H. Martin, Molecular pathology : MP, vol.53, issue.1, pp.8-14, 2000.

B. Sodeik and J. Krijnse-locker, Assembly of vaccinia virus revisited: de novo membrane synthesis or acquisition from the host?, Trends in microbiology, vol.10, issue.1, pp.15-24, 2002.

R. K. Soi, F. R. Rurangirwa, T. C. Mcguire, P. M. Rwambo, J. C. Demartini et al., Protection of sheep against Rift Valley fever virus and sheep poxvirus with a recombinant capripoxvirus vaccine, Clinical and vaccine immunology : CVI, vol.17, issue.12, pp.1842-1851, 2010.

H. P. Sorensen and K. K. Mortensen, Soluble expression of recombinant proteins in the cytoplasm of Escherichia coli. Microbial cell factories, vol.4, p.1, 2005.

V. Sroller, V. Ludvikova, L. Maresova, P. Hainz, and S. Nemeckova, Effect of IFN-gamma receptor gene deletion on vaccinia virus virulence, Archives of virology, vol.146, issue.2, pp.239-288, 2001.

J. Stack, I. R. Haga, M. Schroder, N. W. Bartlett, G. Maloney et al., Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence. The Journal of experimental medicine, vol.201, pp.1007-1025, 2005.

R. J. Stern, J. P. Thompson, and R. W. Moyer, Attenuation of B5R mutants of rabbitpox virus in vivo is related to impaired growth and not an enhanced host inflammatory response, Virology, vol.233, issue.1, pp.118-147, 1997.

E. Stoger, M. Sack, R. Fischer, and P. Christou, Plantibodies: applications, advantages and bottlenecks. Current opinion in biotechnology, vol.13, pp.161-167, 2002.

S. Stubbs, C. A. Oura, M. Henstock, T. R. Bowden, D. P. King et al., Validation of a highthroughput real-time polymerase chain reaction assay for the detection of capripoxviral DNA, Journal of virological methods, vol.179, issue.2, pp.419-441, 2012.

H. P. Su, S. C. Garman, T. J. Allison, C. Fogg, B. Moss et al., The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies, Proceedings of the National Academy of Sciences of the United States of America, vol.102, issue.12, pp.4240-4245, 2005.
URL : https://hal.archives-ouvertes.fr/hal-01595657

H. P. Su, J. W. Golden, A. G. Gittis, J. W. Hooper, and D. N. Garboczi, Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein, Virology, vol.368, issue.2, pp.331-372, 2007.

H. P. Su, K. Singh, A. G. Gittis, and D. N. Garboczi, The structure of the poxvirus A33 protein reveals a dimer of unique C-type lectin-like domains, Journal of virology, vol.84, issue.5, pp.2502-2512, 2010.

T. Takahashi, M. Oie, and Y. Ichihashi, N-terminal amino acid sequences of vaccinia virus structural proteins, Virology, vol.202, issue.2, pp.844-52, 1994.

J. Tang, M. Murtadha, M. Schnell, L. C. Eisenlohr, J. Hooper et al., Human T-cell responses to vaccinia virus envelope proteins, Journal of virology, vol.80, issue.20, pp.10010-10030, 2006.

L. H. Taylor, S. M. Latham, and M. E. Woolhouse, Risk factors for human disease emergence, Philosophical transactions of the Royal Society of London Series B, Biological sciences, vol.356, pp.983-992, 1411.

S. A. Teichmann, A. G. Murzin, and C. Chothia, Determination of protein function, evolution and interactions by structural genomics. Current opinion in structural biology, vol.11, pp.354-63, 2001.

K. Terpe, Overview of bacterial expression systems for heterologous protein production: from molecular and biochemical fundamentals to commercial systems, Applied microbiology and biotechnology, vol.72, issue.2, pp.211-233, 2006.

D. C. Tessier, D. Y. Thomas, H. E. Khouri, F. Laliberte, and T. Vernet, Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide, Gene, vol.98, issue.2, pp.177-83, 1991.

A. D. Thomas, C. Mare, and . Knopvelsiekte, J S AfrVet Assoc, vol.16, pp.36-43, 1945.

J. M. Thornton, C. A. Orengo, A. E. Todd, and F. M. Pearl, Protein folds, functions and evolution, Journal of molecular biology, vol.293, issue.2, pp.333-375, 1999.

H. Tian, Y. Chen, J. Wu, Y. Shang, and X. Liu, Serodiagnosis of sheeppox and goatpox using an indirect ELISA based on synthetic peptide targeting for the major antigen P32, Virology journal, vol.7, p.245, 2010.

A. E. Todd, C. A. Orengo, and J. M. Thornton, Evolution of protein function, from a structural perspective, Silico protein structure and function prediction, vol.3, pp.548-56, 1999.

A. C. Townsley, A. S. Weisberg, T. R. Wagenaar, and B. Moss, Vaccinia virus entry into cells via a low-pHdependent endosomal pathway, Journal of virology, vol.80, issue.18, pp.8899-908, 2006.

J. Trewhella, W. A. Hendrickson, G. J. Kleywegt, A. Sali, M. Sato et al., Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB, Structure, vol.21, issue.6, pp.875-81, 1993.

E. R. Tulman, C. L. Afonso, Z. Lu, L. Zsak, G. F. Kutish et al., Genome of lumpy skin disease virus, Journal of virology, vol.75, issue.15, pp.7122-7152, 2001.

E. R. Tulman, C. L. Afonso, Z. Lu, L. Zsak, J. H. Sur et al., The genomes of sheeppox and goatpox viruses, Journal of virology, vol.76, issue.12, pp.6054-61, 2002.

E. Tuppurainen and N. Galon, Lumpy Skin Disease: Current situation in Europe and neighbouring regions and necessary control measures to halt the spread in South-East Europe. Europe -OIE Regional Commission, 2016.

E. S. Tuppurainen, J. C. Lubinga, W. H. Stoltsz, M. Troskie, S. T. Carpenter et al., Evidence of vertical transmission of lumpy skin disease virus in Rhipicephalus decoloratus ticks. Ticks and tickborne diseases, vol.4, pp.329-362, 2013.

E. S. Tuppurainen, J. C. Lubinga, W. H. Stoltsz, M. Troskie, S. T. Carpenter et al., Mechanical transmission of lumpy skin disease virus by Rhipicephalus appendiculatus male ticks, Epidemiology and infection, vol.141, issue.2, pp.425-455, 2013.

E. S. Tuppurainen and C. A. Oura, Review: lumpy skin disease: an emerging threat to Europe, the Middle East and Asia. Transboundary and emerging diseases, vol.59, pp.40-48, 2012.

E. S. Tuppurainen, C. R. Pearson, K. Bachanek-bankowska, N. J. Knowles, S. Amareen et al., Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus, Antiviral research, vol.109, pp.1-6, 2014.

E. S. Tuppurainen, E. H. Venter, and J. A. Coetzer, The detection of lumpy skin disease virus in samples of experimentally infected cattle using different diagnostic techniques. The Onderstepoort journal of veterinary research, vol.72, pp.153-64, 2005.

E. S. Tuppurainen, E. H. Venter, J. L. Shisler, G. Gari, G. A. Mekonnen et al., Review: Capripoxvirus Diseases: Current Status and Opportunities for Control. Transboundary and emerging diseases, 2015.

A. Untergasser, I. Cutcutache, T. Koressaar, J. Ye, B. C. Faircloth et al., Primer3--new capabilities and interfaces, Nucleic acids research, vol.40, issue.15, p.115, 2012.

C. Upton, S. Slack, A. L. Hunter, A. Ehlers, and R. L. Roper, Poxvirus orthologous clusters: toward defining the minimum essential poxvirus genome, Journal of virology, vol.77, issue.13, pp.7590-600, 2003.

M. Urabe, C. Ding, and R. M. Kotin, Insect cells as a factory to produce adeno-associated virus type 2 vectors, Human gene therapy, vol.13, issue.16, pp.1935-1978, 2002.

H. Van-eijl, M. Hollinshead, G. Rodger, W. H. Zhang, and G. L. Smith, The vaccinia virus F12L protein is associated with intracellular enveloped virus particles and is required for their egress to the cell surface, The Journal of general virology, vol.83, pp.195-207, 2002.

M. H. Van-regenmortel, Antigenicity and immunogenicity of synthetic peptides, Biologicals : journal of the International Association of Biological Standardization, vol.29, issue.3-4, pp.209-222, 2001.

A. Vanderplasschen, M. Hollinshead, and G. L. Smith, Intracellular and extracellular vaccinia virions enter cells by different mechanisms. The Journal of general virology, vol.79, pp.877-87, 1998.

M. I. Vazquez and M. Esteban, Identification of functional domains in the 14-kilodalton envelope protein (A27L) of vaccinia virus, Journal of virology, vol.73, issue.11, pp.9098-109, 1999.

M. I. Vazquez, G. Rivas, D. Cregut, L. Serrano, and M. Esteban, The vaccinia virus 14-kilodalton (A27L) fusion protein forms a triple coiled-coil structure and interacts with the 21-kilodalton (A17L) virus membrane protein through a C-terminal alpha-helix, Journal of virology, vol.72, issue.12, pp.10126-10163, 1998.

G. Venkatesan, V. Balamurugan, and V. Bhanuprakash, Multiplex PCR for simultaneous detection and differentiation of sheeppox, goatpox and orf viruses from clinical samples of sheep and goats, Journal of virological methods, vol.195, pp.1-8, 2014.

G. Venkatesan, V. Balamurugan, and V. Bhanuprakash, TaqMan based real-time duplex PCR for simultaneous detection and quantitation of capripox and orf virus genomes in clinical samples, Journal of virological methods, vol.201, pp.44-50, 2014.

G. Venkatesan, V. Balamurugan, V. Bhanuprakash, R. K. Singh, and A. B. Pandey, Loop mediated isothermal amplification assay for rapid and sensitive detection of sheep pox and goat pox viruses in clinical samples, Mol Cell Probes, vol.16, pp.30014-30021, 2016.

P. H. Verardi, L. A. Jones, F. H. Aziz, S. Ahmad, and T. D. Yilma, Vaccinia virus vectors with an inactivated gamma interferon receptor homolog gene (B8R) are attenuated In vivo without a concomitant reduction in immunogenicity, Journal of virology, vol.75, issue.1, pp.11-19, 2001.

F. Vetrini and P. Ng, Gene therapy with helper-dependent adenoviral vectors: current advances and future perspectives, Viruses, vol.2, issue.9, pp.1886-917, 2010.

B. Vinayagamurthy, D. J. Kallesh, H. Madhusudhan, V. Bhanuprakash, G. Venkatesan et al., Comparative efficacy of conventional and TaqMan polymerase chain reaction assays in the detection of capripoxviruses from clinical samples, Inc, vol.21, pp.225-256, 2009.

M. Wacker, D. Linton, P. G. Hitchen, M. Nita-lazar, S. M. Haslam et al., N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli, Science, vol.298, issue.5599, pp.1790-1793, 2002.

A. M. Wade-evans, C. H. Romero, P. Mellor, H. Takamatsu, J. Anderson et al., Expression of the major core structural protein (VP7) of bluetongue virus, by a recombinant capripox virus, provides partial protection of sheep against a virulent heterotypic bluetongue virus challenge, Virology, vol.220, issue.1, pp.227-258, 1996.

. Wahid, World Animal Health Information Database (WAHIS Interface) -Version 1

E. M. Wall, J. Cao, N. Chen, R. M. Buller, and C. Upton, A novel poxvirus gene and its human homolog are similar to an E. coli lysophospholipase. Virus research, vol.52, pp.157-67, 1997.

D. B. Wallace, C. E. Ellis, A. Espach, S. J. Smith, R. R. Greyling et al., Protective immune responses induced by different recombinant vaccine regimes to Rift Valley fever, Vaccine, vol.24, pp.7181-7190, 2006.

D. B. Wallace and G. J. Viljoen, Immune responses to recombinants of the South African vaccine strain of lumpy skin disease virus generated by using thymidine kinase gene insertion, Vaccine, vol.23, issue.23, pp.3061-3068, 2005.

K. Wallengren, C. Risco, J. Krijnse-locker, E. M. Rodriguez, and D. , The A17L gene product of vaccinia virus is exposed on the surface of IMV, Virology, vol.290, issue.1, pp.143-52, 2001.

A. M. Walmsley and C. J. Arntzen, Plant cell factories and mucosal vaccines. Current opinion in biotechnology, vol.14, pp.145-50, 2003.

W. Walther and U. Stein, Viral vectors for gene transfer: a review of their use in the treatment of human diseases, Drugs, vol.60, issue.2, pp.249-71, 2000.

T. Walzthoeni, A. Leitner, F. Stengel, and R. Aebersold, Mass spectrometry supported determination of protein complex structure. Current opinion in structural biology, vol.23, pp.252-60, 2013.

D. R. Wang, J. C. Hsiao, C. H. Wong, G. C. Li, S. C. Lin et al., Vaccinia viral protein A27 is anchored to the viral membrane via a cooperative interaction with viral membrane protein A17, The Journal of biological chemistry, vol.289, issue.10, pp.6639-55, 2014.

H. W. Wang and J. W. Wang, How cryo-electron microscopy and X-ray crystallography complement each other. Protein science : a publication of the Protein Society, vol.26, pp.32-41, 2017.

B. M. Ward, Visualization and characterization of the intracellular movement of vaccinia virus intracellular mature virions, Journal of virology, vol.79, issue.8, pp.4755-63, 2005.

B. M. Ward, A. S. Weisberg, and B. Moss, Mapping and functional analysis of interaction sites within the cytoplasmic domains of the vaccinia virus A33R and A36R envelope proteins, Journal of virology, vol.77, issue.7, pp.4113-4139, 2003.

D. E. Weidhaas and D. G. Haile, A theoretical model to determine the degree of trapping required for insect population control, Entomol Soc Am Bull, vol.24, pp.18-20, 1987.

K. E. Weiss, Lympy skin disease virus, Virol Monogr, vol.3, pp.111-142, 1968.

B. E. Wilkinson and M. Cox, Baculovirus expression system: the production of proteins for diagnostic, human therapeutic or vaccine use, Gen Eng News, vol.18, p.35, 1998.

D. O. Willer, G. Mcfadden, and D. H. Evans, The complete genome sequence of shope (rabbit) fibroma virus, Virology, vol.264, issue.2, pp.319-362, 1999.

L. M. Wise, T. Veikkola, A. A. Mercer, L. J. Savory, S. B. Fleming et al., Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1, Proceedings of the National Academy of Sciences of the United States of America, vol.96, issue.6, pp.3071-3077, 1999.

E. J. Wolffe, S. N. Isaacs, and B. Moss, Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination, Journal of virology, vol.67, issue.8, pp.4732-4773, 1993.

E. J. Wolffe, S. Vijaya, and B. Moss, A myristylated membrane protein encoded by the vaccinia virus L1R open reading frame is the target of potent neutralizing monoclonal antibodies, Virology, vol.211, issue.1, pp.53-63, 1995.

E. J. Wolffe, A. S. Weisberg, and B. Moss, The vaccinia virus A33R protein provides a chaperone function for viral membrane localization and tyrosine phosphorylation of the A36R protein, Journal of virology, vol.75, issue.1, pp.303-313, 2001.

J. A. Woods, Lumpy skin disease-a review. Tropical animal health and production, vol.20, pp.11-18, 1988.

P. E. Wright and H. J. Dyson, Intrinsically unstructured proteins: re-assessing the protein structurefunction paradigm, Journal of molecular biology, vol.293, issue.2, pp.321-352, 1999.

H. Wu, J. Guo, S. Chen, X. Liu, Y. Zhou et al., Recent developments in qualitative and quantitative analysis of phytochemical constituents and their metabolites using liquid chromatography-mass spectrometry, Journal of pharmaceutical and biomedical analysis, vol.72, pp.267-91, 2013.

F. Wurm and A. Bernard, Large-scale transient expression in mammalian cells for recombinant protein production. Current opinion in biotechnology, vol.10, pp.156-165, 1999.

Y. Xiao, L. Aldaz-carroll, A. M. Ortiz, J. C. Whitbeck, A. E. Lou et al., A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost, Vaccine, vol.25, issue.7, pp.1214-1238, 2007.

Y. Xiao, Y. Zeng, A. E. Mehta, S. Joshi, S. B. Buchman et al., Adsorption of recombinant poxvirus L1-protein to aluminum hydroxide/CpG vaccine adjuvants enhances immune responses and protection of mice from vaccinia virus challenge, Vaccine, vol.31, issue.2, pp.319-345, 2013.

H. Yamaji, Suitability and perspectives on using recombinant insect cells for the production of virus-like particles, Applied microbiology and biotechnology, vol.98, issue.5, pp.1963-70, 2014.

X. M. Yan, Y. F. Chu, G. H. Wu, Z. X. Zhao, J. Li et al., An outbreak of sheep pox associated with goat poxvirus in Gansu province of China, Veterinary microbiology, vol.156, issue.3-4, pp.425-433, 2012.

Z. R. Yang, R. Thomson, P. Mcneil, and R. M. Esnouf, RONN: the bio-basis function neural network technique applied to the detection of natively disordered regions in proteins, Bioinformatics, vol.21, issue.16, pp.3369-76, 2005.

I. Yeruham, O. Nir, Y. Braverman, M. Davidson, H. Grinstein et al., Spread of lumpy skin disease in Israeli dairy herds. The Veterinary record, vol.137, pp.91-94, 1995.

I. Yeruham, H. Yadin, V. Ham, M. Bumbarov, V. Soham et al., Economic and epidemiological aspects of an outbreak of sheeppox in a dairy sheep flock. The Veterinary record, vol.160, pp.236-243, 2007.

H. Yokote, Y. Shinmura, T. Kanehara, S. Maruno, M. Kuranaga et al., Vaccinia virus strain LC16m8 defective in the B5R gene keeps strong protection comparable to its parental strain Lister in immunodeficient mice, Vaccine, vol.33, issue.45, pp.6112-6121, 2015.

R. J. Youle and A. Strasser, The BCL-2 protein family: opposing activities that mediate cell death, Nature reviews Molecular cell biology, vol.9, issue.1, pp.47-59, 2008.

H. Yu, J. Chen, S. Liu, A. Zhang, X. Xu et al., Large-Scale Production of Functional Human Lysozyme in Transgenic Cloned Goats, Journal of biotechnology, 2013.

I. K. Zangana and M. A. , Epidemiological, clinical and histopathological studies of lamb and kid pox in Duhok, Iraq. Bulgarian J Vet Med, vol.16, pp.133-141, 2013.

A. N. Zelensky and J. E. Gready, The C-type lectin-like domain superfamily, FEBS J, vol.272, pp.6179-217, 2005.

S. Zeynalova, K. Asadov, F. Guliyev, M. Vatani, and V. Aliyev, Epizootology and Molecular Diagnosis of Lumpy Skin Disease among Livestock in Azerbaijan, Frontiers in microbiology, vol.7, p.1022, 2016.

Y. Zhang, Interplay of I-TASSER and QUARK for template-based and ab initio protein structure prediction in CASP10, Proteins, vol.82, issue.2, pp.175-87, 2014.

Z. Zhao, B. Fan, G. Wu, X. Yan, Y. Li et al., Development of loop-mediated isothermal amplification assay for specific and rapid detection of differential goat pox virus and sheep pox virus, BMC microbiology, vol.14, p.10, 2014.

M. Zheng, J. N. Liu, Q. Huo, X. Li, Y. Hu et al., Immunogenicity and protective efficacy of Semliki forest virus replicon-based DNA vaccines encoding goatpox virus structural proteins, Virology, vol.391, issue.1, pp.33-43, 2009.

M. Zheng, Q. Liu, J. N. Guo, J. Huang, X. Li et al., A duplex PCR assay for simultaneous detection and differentiation of Capripoxvirus and Orf virus. Molecular and cellular probes, vol.21, pp.276-81, 2007.

K. Zro, S. Azelmat, Y. Bendouro, J. H. Kuhn, E. El-fahime et al., PCR-based assay to detect sheeppox virus in ocular, nasal, and rectal swabs from infected Moroccan sheep, Journal of virological methods, vol.204, pp.38-43, 2014.

, Annexe 4 : Purification de l'ARN total à partir des cellules animales par la « Spin » technologie

, Lyse des cellules en ajoutant un volume approprié de tampon RLT (350 à 600ul)

, Homogénéiser le lysat en le plaçant dans une colonne « QIAshredder spin column » placée dans un collection tube de 2 ml, puis centrifugation à vitesse maximale (13000 rpm) pendant 2 minutes

, Ajouter un volume d'éthanol à 70% au lysat homogénéisé, bien mélanger par pipetage/refoulement

, Transférer jusqu'à 700 ul de l'échantillon à la colonne « RNeasy spin column » placé dans un collection tube de 2 ml. Centrifuger pendant 15 secondes à > 10000 rpm

, Ajouter 700 ul de tampon RLT à la colonne RNeasy. Centrifuger pendant 15 secondes à 10000 rpm pour laver la membrane de la colonne

, Ajouter 500ul de tampon RPE à la colonne RNeasy et centrifuger pendant 2 minutes à 10000 rpm. Cette longue centrifugation va faire sécher la membrane de la colonne pour s'assurer de l'absence de l'éthanol lors de l

, Elution de l'ARN : Placer la colonne RNeasy dans un nouveau tube eppendorf de 1,5 ml. Ajouter 30 à 50 ul d'eau RNAse free directement au centre de la colonne, Centrifuger pendant 1 minute à 10000 rpm