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Développement d'une capsule de prélèvement de microbiote intestinal utilisant un mécanisme bistable et exploitant la fabrication additive

Mouna Ben Salem 1
1 DEXTER - Conception et commande de robots pour la manipulation
LIRMM - Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier
Abstract : The diagnosis and the treatment of gastro-intestinal pathologies have experienced significant development in recent years with the invention of endoscopic capsules which facilitate the access to different sections of the gastro-intestinal tract.Although these capsules can perform several functions such as gastrointestinal tract inspection and drug delivery, microbiota sampling still requires surgery in order to collect intestinal liquid samples.We propose through this work a microbiota sampling device that navigates through the gastro-intestinal tract, takes a sample of the intestinal fluid and protects it from any contamination as the device navigates in the human body. We use a bistable structure to close the capsule after sampling and a sponge for the triggering.The device is safe for the human body, as it does not contain electronic components, batteries and does not require any external intervention.To manufacture the microbiota sampling capsule, we use additive manufacturing. This technology offers the use of biocompatible material at a relatively low cost and allows fast prototyping cycle.
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Submitted on : Monday, September 14, 2020 - 9:41:10 AM
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Mouna Ben Salem. Développement d'une capsule de prélèvement de microbiote intestinal utilisant un mécanisme bistable et exploitant la fabrication additive. Micro et nanotechnologies/Microélectronique. Université Montpellier, 2020. Français. ⟨NNT : 2020MONTS002⟩. ⟨tel-02935847v2⟩

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