T. Akema, N. Mitsugi, Y. Tadokoro, and F. Kimura, Differential Changes in the Mechanisms Controlling Luteinizing Hormone and Prolactin Secretion in Middle-Aged Female Rats, Endocrinologia Japonica, vol.32, issue.1, pp.153-61, 1985.

S. M. Biello, Circadian Clock Resetting in the Mouse Changes with Age, Age, vol.31, issue.4, pp.293-303, 2009.

C. A. Christian, J. L. Mobley, and S. M. Moenter, Diurnal and Estradiol-Dependent Changes in Gonadotropin-Releasing Hormone Neuron Firing Activity, Proceedings of the National Academy of Sciences of the United States of America, vol.102, issue.43, pp.15682-87, 2005.

K. Czieselsky, M. Prescott, R. Porteous, P. Campos, J. Clarkson et al., Pulse and Surge Profiles of Luteinizing Hormone Secretion in the Mouse, Endocrinology, vol.157, issue.12, pp.4794-4802, 2016.

L. V. Depaolo and S. C. Chappel, Alterations in the Secretion and Production of Follicle-Stimulating Hormone Precede Age-Related Lengthening of Estrous Cycles in Rats, Endocrinology, vol.118, issue.3, pp.1127-1160, 1986.

J. L. Downs and P. M. Wise, The Role of the Brain in Female Reproductive Aging, Molecular and Cellular Endocrinology, vol.299, issue.1, pp.32-38, 2009.

T. L. Habermehl, K. C. Parkinson, G. B. Hubbard, Y. Ikeno, J. I. Engelmeyer et al., Extension of Longevity and Reduction of Inflammation Is Ovarian-Dependent, but Germ Cell-Independent in Post-Reproductive Female Mice, GeroScience, vol.41, issue.1, pp.25-38, 2019.

M. N. Ishii, K. Matsumoto, H. Matsui, N. Seki, H. Matsumoto et al., Reduced Responsiveness of Kisspeptin Neurons to Estrogenic Positive Feedback Associated with Age-Related Disappearance of LH Surge in Middle-Age Female Rats, General and Comparative Endocrinology, vol.193, pp.121-150, 2013.

B. Kerdelhué, S. Brown, V. Lenoir, J. T. Queenan, G. S. Jones et al., Timing of Initiation of the Preovulatory Luteinizing Hormone Surge and Its Relationship with the Circadian Cortisol Rhythm in the Human, Neuroendocrinology, vol.75, issue.3, pp.158-63, 2002.

K. Krajnak, M. L. Kashon, K. L. Rosewell, and P. M. Wise, Aging Alters the Rhythmic Expression of Vasoactive Intestinal Polypeptide MRNA but Not Arginine Vasopressin MRNA in the Suprachiasmatic Nuclei of Female Rats, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.18, issue.12, pp.4767-74, 1998.

Y. Kunimura, K. Iwata, A. Ishigami, and H. Ozawa, Age-Related Alterations in Hypothalamic Kisspeptin, Neurokinin B, and Dynorphin Neurons and in Pulsatile LH Release in Female and Male Rats, Neurobiology of Aging, vol.50, pp.30-38, 2017.

I. Lawrence, M. Bene, T. Nacarelli, A. Azar, J. Z. Cohen et al., Correlations between Age, Functional Status, and the Senescence-Associated Proteins HMGB2 and P16INK4a, vol.40, pp.193-99, 2018.

M. A. Lederman, D. Lebesgue, V. V. Gonzalez, J. Shu, Z. O. Merhi et al., Age-Related LH Surge Dysfunction Correlates with Reduced Responsiveness of Hypothalamic Anteroventral Periventricular Nucleus Kisspeptin Neurons to Estradiol Positive Feedback in Middle-Aged Rats, Neuropharmacology, vol.58, issue.1, pp.314-334, 2010.

S. J. Legan and F. J. Karsch, A Daily Signal for the LH Surge in the Rat, Endocrinology, vol.96, issue.1, pp.57-62, 1975.

J. M. Lloyd, G. E. Hoffman, and P. M. Wise, Decline in Immediate Early Gene Expression in Gonadotropin-Releasing Hormone Neurons during Proestrus in Regularly Cycling, Middle-Aged Rats, Endocrinology, vol.134, issue.4, pp.1800-1805, 1994.

M. M. Mahoney, C. Sisk, H. E. Ross, and L. Smale, Circadian Regulation of Gonadotropin-Releasing Hormone Neurons and the Preovulatory Surge in Luteinizing Hormone in the Diurnal Rodent, Arvicanthis Niloticus, and in a Nocturnal Rodent, Rattus Norvegicus. Biology of Reproduction, vol.70, issue.4, pp.1049-54, 2004.

,

C. Marquez, J. A. Ibana, and M. C. Velarde, The Female Reproduction and Senescence Nexus, American Journal of Reproductive Immunology, vol.77, issue.5, p.12646, 1989.

D. W. Matt, M. P. Gilson, T. E. Sales, R. J. Krieg, M. C. Kerbeshian et al., Characterization of Attenuated Proestrous Luteinizing Hormone Surges in Middle-Aged Rats by Deconvolution Analysis, Biology of Reproduction, vol.59, issue.6, pp.1477-82, 1998.

A. C. Mclean, N. Valenzuela, S. Fai, and S. A. Bennett, Performing Vaginal Lavage, Crystal Violet Staining, and Vaginal Cytological Evaluation for Mouse Estrous Cycle Staging Identification, Journal of Visualized Experiments : JoVE, issue.67, p.4389, 2012.

C. V. Mobbs, D. M. Gee, and C. E. Finch, Reproductive Senescence in Female C57BL/6J Mice: Ovarian Impairments and Neuroendocrine Impairments That Are Partially Reversible and Delayable by Ovariectomy, Endocrinology, vol.115, issue.5, pp.1653-62, 1984.

T. E. Nass, P. S. Lapolt, H. L. Judd, and J. K. Lu, Alterations in Ovarian Steroid and Gonadotrophin Secretion Preceding the Cessation of Regular Oestrous Cycles in Ageing Female Rats, The Journal of Endocrinology, vol.100, issue.1, pp.43-50, 1984.

G. Neal-perry, D. Lebesgue, M. Lederman, J. Shu, G. D. Zeevalk et al., The Excitatory Peptide Kisspeptin Restores the Luteinizing Hormone Surge and Modulates Amino Acid Neurotransmission in the Medial Preoptic Area of Middle-Aged Rats, Endocrinology, vol.150, issue.8, pp.3699-3708, 2009.

J. F. Nelson, L. S. Felicio, P. K. Randall, C. Sims, and C. E. Finch, A Longitudinal Study of Estrous Cyclicity in Aging C57BL/6J Mice: I. Cycle Frequency, Length and Vaginal Cytology, Biology of Reproduction, vol.27, issue.2, pp.327-366, 1982.

T. A. Parkening, T. J. Collins, and E. R. Smith, Plasma and Pituitary Concentrations of LH, FSH, and Prolactin in Aging C57BL/6 Mice at Various Times of the Estrous Cycle, Neurobiology of Aging, vol.3, issue.1, pp.31-35, 1982.

, , pp.90058-90064

K. M. Perrott, C. D. Wiley, P. Y. Desprez, and J. Campisi, Apigenin Suppresses the Senescence-Associated Secretory Phenotype and Paracrine Effects on, Breast Cancer Cells. GeroScience, vol.39, issue.2, pp.161-73, 2017.

,

R. Piet, A. Fraissenon, U. Boehm, and A. E. Herbison, Estrogen Permits Vasopressin Signaling in Preoptic Kisspeptin Neurons in the Female Mouse, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.35, issue.17, pp.6881-92, 2015.

L. Pinilla, E. Aguilar, C. Dieguez, R. P. Millar, and M. Tena-sempere, Kisspeptins and Reproduction: Physiological Roles and Regulatory Mechanisms, Physiological Reviews, vol.92, issue.3, pp.1235-1316, 2012.

,

B. S. Rubin, C. E. Lee, and J. C. King, A Reduced Proportion of Luteinizing Hormone (LH)-Releasing Hormone Neurons Express Fos Protein during the Preovulatory or Steroid-Induced LH Surge in Middle-Aged Rats, Biology of Reproduction, vol.51, issue.6, pp.1264-72, 1994.

B. S. Rubin, S. Mitchell, C. E. Lee, and J. C. King, Reconstructions of Populations of Luteinizing Hormone Releasing Hormone Neurons in Young and Middle-Aged Rats Reveal Progressive Increases in Subgroups Expressing Fos Protein on Proestrus and Age-Related Deficits, Endocrinology, vol.136, issue.9, pp.3823-3853, 1995.

,

J. Shi, B. Zhang, J. Y. Choi, Y. T. Gao, H. Li et al., Age at Menarche and Age at Natural Menopause in East Asian Women: A Genome-Wide Association Study, AGE, vol.38, pp.513-536, 2016.

,

K. Shirasuna and H. Iwata, Effect of Aging on the Female Reproductive Function, Contraception and Reproductive Medicine, vol.2, issue.1, p.23, 2017.

V. Simonneaux and T. Bahougne, A Multi-Oscillatory Circadian System Times Female Reproduction, Frontiers in Endocrinology, vol.6, 2015.

J. T. Smith, S. M. Popa, D. K. Clifton, G. E. Hoffman, and R. A. Steiner, Kiss1 Neurons in the Forebrain as Central Processors for Generating the Preovulatory Luteinizing Hormone Surge, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.26, issue.25, pp.6687-94, 2006.

F. J. Steyn, Y. Wan, J. Clarkson, J. D. Veldhuis, A. E. Herbison et al., Development of a Methodology for and Assessment of Pulsatile Luteinizing Hormone Secretion in Juvenile and Adult Male Mice, Endocrinology, vol.154, issue.12, pp.4939-4984, 2013.

B. Vida, L. Deli, E. Hrabovszky, T. Kalamatianos, A. Caraty et al., Evidence for, 2010.
URL : https://hal.archives-ouvertes.fr/hal-01129478

, Suprachiasmatic Vasopressin Neurones Innervating Kisspeptin Neurones in the Rostral Periventricular Area of the Mouse Brain: Regulation by Oestrogen, Journal of Neuroendocrinology, vol.22, issue.9, pp.1032-1071

,

P. M. Wise, Alterations in Proestrous LH, FSH, and Prolactin Surges in Middle-Aged Rats, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine, vol.169, issue.3, pp.348-54, 1982.

J. Zhang, L. Yang, N. Lin, X. Pan, Y. Zhu et al., Aging-Related Changes in RP3V Kisspeptin Neurons Predate the Reduced Activation of GnRH Neurons during the Early Reproductive Decline in Female Mice, Neurobiology of Aging, vol.35, issue.3, pp.655-68, 2014.

V. Simonneaux, T. Bahougne, and . Multi, Oscillatory Circadian System Times Female Reproduction. Front. Endocrinol. (Lausanne), vol.6, p.157, 2015.

J. E. Levine, Neuroendocrine control of the ovarian cycle of the rat, TM Plant & AJ Zeleznic, 2015.

M. S. Smith, M. E. Freeman, and J. D. Neill, The Control of Progesterone Secretion During the Estrous Cycle and Early Pseudopregnancy in the Rat: Prolactin, Gonadotropin and Steroid Levels Associated with Rescue of the Corpus Luteum of Pseudopregnancy, Endocrinology, vol.96, issue.1, pp.219-226, 1975.

F. H. Bronson, V. Saal, and F. S. , Control of the preovulatory release of luteinizing hormone by steroids in the mouse, Endocrinology, vol.104, issue.5, pp.1247-55, 1979.

M. L. Moline, H. E. Albers, R. B. Todd, and M. Mc, Light-dark entrainment of proestrous LH surges and circadian locomotor activity in female hamsters, Horm. Behav, vol.15, issue.4, pp.451-459, 1981.

T. L. Mcelhinny, C. L. Sisk, K. E. Holekamp, and L. Smale, A morning surge in plasma luteinizing hormone coincides with elevated Fos expression in gonadotropin-releasing hormone-immunoreactive neurons in the diurnal rodent, Arvicanthis niloticus, Biol. Reprod, vol.61, issue.4, pp.1115-1137, 1999.

D. J. Cahill, P. G. Wardle, C. R. Harlow, and M. G. Hull, Onset of the preovulatory luteinizing hormone surge: diurnal timing and critical follicular prerequisites, Fertil. Steril, vol.70, issue.1, pp.56-65, 1998.

B. Kerdelhué, S. Brown, V. Lenoir, J. T. Queenan, G. S. Jones et al., Timing of initiation of the preovulatory luteinizing hormone surge and its relationship with the circadian cortisol rhythm in the human, Neuroendocrinology, vol.75, issue.3, pp.158-63, 2002.

K. Brown-grant and G. Raisman, Abnormalities in reproductive function associated with the destruction of the suprachiasmatic nuclei in female rats, Proc. R. Soc. London. Ser. B, Biol. Sci, vol.198, pp.279-96, 1132.

B. H. Miller, S. L. Olson, F. W. Turek, J. E. Levine, T. H. Horton et al., Circadian clock mutation disrupts estrous cyclicity and maintenance of pregnancy, Curr. Biol, vol.14, issue.15, pp.1367-73, 2004.

C. Pati and R. , Shift work: consequences and management, Curr Sci, vol.81, pp.32-52, 2001.

A. Pan, E. S. Schernhammer, Q. Sun, and F. B. Hu, Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women. Groop L, ed, PLoS Med, vol.8, issue.12, p.1001141, 2011.

D. B. Boivin and P. Boudreau, Impacts of shift work on sleep and circadian rhythms, Pathol. Biol, vol.62, issue.5, pp.292-301, 2014.

É. Cordina-duverger, M. Houot, N. Tvardik, M. El-yamani, C. Pilorget et al., Prevalence of night work in France: characterization from a job-exposure matrix, Bull. épidémiologique Hebd, vol.8, issue.9, pp.168-174, 2018.

K. L. Gamble, D. Resuehr, and C. H. Johnson, Shift work and circadian dysregulation of reproduction, Front. Endocrinol. (Lausanne), vol.4, p.92, 2013.

V. Simonneaux, T. Bahougne, and E. Angelopoulou, Daily rhythms count for female fertility, Best Pract. Res. Clin. Endocrinol. Metab, issue.5, p.31, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02390100

J. S. Finkelstein, F. R. Baum, and C. S. Campbell, Entrainment of the female hamster to reversed photoperiod: role of the pineal, Physiol. Behav, vol.21, issue.1, pp.105-116, 1978.

M. L. Moline and H. E. Albers, Response of circadian locomotor activity and the proestrous luteinizing hormone surge to phase shifts of the light-dark cycle in the hamster, Physiol. Behav, vol.43, issue.4, pp.435-475, 1988.

K. Yoshinaka, A. Yamaguchi, R. Matsumura, K. Node, I. Tokuda et al., Effect of different light-dark schedules on estrous cycle in mice, and implications for mitigating the adverse impact of night work, Genes Cells, vol.22, issue.10, pp.876-884, 2017.

T. Bahougne, E. Angelopoulou, N. Jeandidier, and V. Simonneaux, Individual evaluation of luteinizing hormone in aged C57BL/6 J female mice. GeroScience, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02390065

I. Bartol-munier, S. Gourmelen, P. Pevet, and E. Challet, Combined effects of high-fat feeding and circadian desynchronization, Int. J. Obes. (Lond), vol.30, issue.1, pp.60-67, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00022976

J. F. Nelson, L. S. Felicio, P. K. Randall, C. Sims, and C. E. Finch, A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology, Biol. Reprod, vol.27, issue.2, pp.327-366, 1982.

F. J. Steyn, Y. Wan, J. Clarkson, J. D. Veldhuis, A. E. Herbison et al., Development of a methodology for and assessment of pulsatile luteinizing hormone secretion in juvenile and adult male mice, Endocrinology, vol.154, issue.12, pp.4939-4984, 2013.

J. F. Nelson, G. Goodrick, K. Karelus, and L. S. Felicio, Longitudinal studies of estrous cyclicity in C57BL/6J mice: III. Dietary modulation declines during aging, Mech. Ageing Dev, vol.48, issue.1, pp.73-84, 1989.

. Opperhuizen, L. Van-kerkhof, K. I. Proper, W. Rodenburg, and A. Kalsbeek, Rodent models to study the metabolic effects of shiftwork in humans, Front. Pharmacol, vol.6, p.50, 2015.

M. Vyas, A. X. Garg, A. Iansavichus, J. Costella, A. Donner et al., Shift work and vascular events: systematic review and meta-analysis, BMJ, vol.345, issue.jul26_1, p.4800, 2012.

F. Menegaux, T. Truong, A. Anger, E. Cordina-duverger, F. Lamkarkach et al., Night work and breast cancer: a population-based case-control study in France (the CECILE study), Int. J. cancer, vol.132, issue.4, pp.924-955, 2013.

Y. Gan, C. Yang, X. Tong, H. Sun, Y. Cong et al., Shift work and diabetes mellitus: a meta-analysis of observational studies, Occup. Environ. Med, vol.72, issue.1, pp.72-78, 2015.

H. A. Kolstad, J. P. Bonde, N. H. Hjøllund, T. K. Jensen, T. B. Henriksen et al., Menstrual cycle pattern and fertility: a prospective follow-up study of pregnancy and early embryonal loss in 295 couples who were planning their first pregnancy, Fertil. Steril, vol.71, issue.3, pp.490-496, 1999.

E. Guermandi, W. Vegetti, M. M. Bianchi, A. Uglietti, G. Ragni et al., Reliability of ovulation tests in infertile women, Obstet. Gynecol, vol.97, issue.1, pp.92-98, 2001.

N. N. Takasu, T. J. Nakamura, I. T. Tokuda, T. Todo, G. D. Block et al., Recovery from Age-Related Infertility under Environmental Light-Dark Cycles Adjusted to the Intrinsic Circadian Period, Cell Rep, vol.12, issue.9, pp.1407-1420, 2015.

C. A. Christian, J. L. Mobley, and S. M. Moenter, Diurnal and estradiol-dependent changes in gonadotropin-releasing hormone neuron firing activity, Proc. Natl. Acad. Sci. U. S. A, vol.102, issue.43, pp.15682-15689, 2005.

C. E. Mccormack, Acute effects of altered photoperiods on the onset of ovulation in gonadotropin-treated immature rats, Endocrinology, vol.93, issue.2, pp.403-413, 1973.

J. J. Alleva, M. Waleski, F. R. Alleva, and E. J. Umberger, Synchronizing effect of photoperiodicity on ovulation in hamsters, Endocrinology, vol.82, issue.6, pp.1227-1262, 1968.

I. H. Kaiser, Effect of a 28 hour day on ovulation and reproduction in mice, Am. J. Obstet. Gynecol, vol.99, issue.6, pp.772-84, 1967.

P. M. Wise, Alterations in proestrous LH, FSH, and prolactin surges in middle-aged rats, Proc. Soc. Exp. Biol. Med, vol.169, issue.3, pp.348-54, 1982.

T. E. Nass, P. S. Lapolt, H. L. Judd, and J. K. Lu, Alterations in ovarian steroid and gonadotrophin secretion preceding the cessation of regular oestrous cycles in ageing female rats, J. Endocrinol, vol.100, issue.1, pp.43-50, 1984.

T. Akema, N. Mitsugi, Y. Tadokoro, and F. Kimura, Differential changes in the mechanisms controlling luteinizing hormone and prolactin secretion in middle-aged female rats, Endocrinol. Jpn, vol.32, issue.1, pp.153-161, 1985.

L. Depaolo and S. C. Chappel, Alterations in the secretion and production of follicle-stimulating hormone precede age-related lengthening of estrous cycles in rats, Endocrinology, vol.118, issue.3, pp.1127-1160, 1986.

D. W. Matt, M. P. Gilson, T. E. Sales, R. J. Krieg, M. C. Kerbeshian et al., Characterization of attenuated proestrous luteinizing hormone surges in middle-aged rats by deconvolution analysis, Biol. Reprod, vol.59, issue.6, pp.1477-82, 1998.

D. Stock, J. A. Knight, J. Raboud, M. Cotterchio, S. Strohmaier et al., Rotating night shift work and menopausal age, Hum. Reprod, vol.34, issue.3, pp.539-548, 2019.

K. C. Summa, M. H. Vitaterna, and F. W. Turek, Environmental perturbation of the circadian clock disrupts pregnancy in the mouse, PLoS One, vol.7, issue.5, p.37668, 2012.

T. J. Varcoe, N. Wight, A. Voultsios, M. D. Salkeld, and D. J. Kennaway, Chronic phase shifts of the photoperiod throughout pregnancy programs glucose intolerance and insulin resistance in the rat, PLoS One, vol.6, issue.4, p.18504, 2011.

. Simonneaux, A Kiss to drive rhythms in reproduction, Eur. J. Neurosci, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02390080

V. Pilorz and S. Steinlechner, Low reproductive success in Per1 and Per2 mutant mouse females due to accelerated ageing?, Reproduction, vol.135, issue.4, pp.559-68, 2008.

Y. Liu, B. P. Johnson, A. L. Shen, J. A. Wallisser, K. J. Krentz et al., Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice, Proc. Natl. Acad. Sci. U. S. A, vol.111, issue.39, pp.14295-300, 2014.

A. L. Mereness, Z. C. Murphy, A. C. Forrestel, S. Butler, C. Ko et al., Conditional Deletion of Bmal1 in Ovarian Theca Cells Disrupts Ovulation in Female Mice, Endocrinology, vol.157, issue.2, pp.913-940, 2016.

S. Yamazaki, R. Numano, M. Abe, A. Hida, R. Takahashi et al., Resetting central and peripheral circadian oscillators in transgenic rats, Science, vol.288, issue.5466, pp.682-687, 2000.

T. Yoshikawa, M. Sellix, P. Pezuk, and M. Menaker, Timing of the ovarian circadian clock is regulated by gonadotropins, Endocrinology, vol.150, issue.9, pp.4338-4385, 2009.

B. Goichot, L. Weibel, F. Chapotot, C. Gronfier, F. Piquard et al., Effect of the shift of the sleepwake cycle on three robust endocrine markers of the circadian clock, Am. J. Physiol, vol.275, issue.2, pp.243-251, 1998.

. Oster, Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag. -PubMed -NCBI, J Clin Invest, pp.2600-2609, 2010.

H. C. Atkinson and B. J. Waddell, Circadian variation in basal plasma corticosterone and adrenocorticotropin in the rat: sexual dimorphism and changes across the estrous cycle, Endocrinology, vol.138, issue.9, pp.3842-3850, 1997.

L. Manenschijn, R. Van-kruysbergen, F. H. De-jong, J. W. Koper, and E. Van-rossum, Shift work at young age is associated with elevated long-term cortisol levels and body mass index, J. Clin. Endocrinol. Metab, vol.96, issue.11, pp.1862-1867, 2011.

S. Whirledge and J. A. Cidlowski, A Role for Glucocorticoids in Stress-Impaired Reproduction: Beyond the Hypothalamus and Pituitary, Endocrinology, vol.154, issue.12, pp.4450-4468, 2013.

R. Pivonello, A. M. Isidori, D. Martino, M. C. Newell-price, J. Biller et al., Complications of Cushing's syndrome: state of the art, Lancet Diabetes Endocrinol, vol.4, issue.7, pp.611-629, 2016.

K. Takumi, N. Iijima, S. Higo, and H. Ozawa, Immunohistochemical analysis of the colocalization of corticotropinreleasing hormone receptor and glucocorticoid receptor in kisspeptin neurons in the hypothalamus of female rats, Neurosci. Lett, vol.531, issue.1, pp.40-45, 2012.

K. M. Breen and P. L. Mellon, Influence of stress-induced intermediates on gonadotropin gene expression in gonadotrope cells, Mol. Cell. Endocrinol, vol.385, issue.1-2, pp.71-77, 2014.

E. Luo, S. Stephens, S. Chaing, N. Munaganuru, A. S. Kauffman et al., Corticosterone blocks ovarian cyclicity and the LH surge via decreased kisspeptin neuron activation in female mice, Endocrinology, p.20151711, 2015.

J. L. Barclay, J. Husse, B. Bode, N. Naujokat, J. Meyer-kovac et al., Circadian Desynchrony Promotes Metabolic Disruption in a Mouse Model of Shiftwork. Mistlberger RE, PLoS One, vol.7, issue.5, p.37150, 2012.

P. Tucker, J. Marquié, S. Folkard, D. Ansiau, and Y. Esquirol, Shiftwork and metabolic dysfunction, Chronobiol. Int, vol.29, issue.5, pp.549-55, 2012.

R. J. Norman and A. M. Clark, Obesity and reproductive disorders: a review, Reprod. Fertil. Dev, vol.10, issue.1, p.55, 1998.

A. M. Clark, B. Thornley, L. Tomlinson, C. Galletley, and R. J. Norman, Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment, Hum. Reprod, vol.13, issue.6, pp.1502-1507, 1998.

K. Mounzih, R. Lu, and F. F. Chehab, Leptin Treatment Rescues the Sterility of Genetically Obese ob/ob Males, Endocrinology, vol.138, issue.3, pp.1190-1193, 1997.

A. Abbara, C. N. Jayasena, G. Christopoulos, S. Narayanaswamy, C. Izzi-engbeaya et al., Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF), 2015.

, The Journal of Clinical Endocrinology and Metabolism, vol.100, issue.9, pp.3322-3353

,

K. Abe and T. , Rapid Action of Estrogens on Intracellular Calcium Oscillations in Primate Luteinizing Hormone-Releasing Hormone-1 Neurons, Endocrinology, vol.149, issue.3, pp.1155-62, 2008.

M. Abe, E. D. Herzog, S. Yamazaki, M. Straume, H. Tei et al., Circadian Rhythms in Isolated Brain Regions, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.22, issue.1, pp.350-56, 2002.

A. and T. , Firing Pattern and Rapid Modulation of Activity by Estrogen in Primate Luteinizing Hormone Releasing Hormone-1 Neurons, Endocrinology, vol.146, issue.10, pp.4312-4332, 2005.

. Abrahám, M. István, S. Han, G. Martin, . Todman et al., Estrogen Receptor Beta Mediates Rapid Estrogen Actions on Gonadotropin-Releasing Hormone Neurons in Vivo, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.23, issue.13, pp.5771-77, 2003.

S. Adachi, S. Yamada, Y. Takatsu, H. Matsui, M. Kinoshita et al., Involvement of Anteroventral Periventricular Metastin/Kisspeptin Neurons in Estrogen Positive Feedback Action on Luteinizing Hormone Release in Female Rats, The Journal of Reproduction and Development, vol.53, issue.2, pp.367-78, 2007.

J. M. Adams, A. Taylor, D. Schoenfeld, W. Crowley, and J. Hall, The Midcycle Gonadotropin Surge in Normal Women Occurs in the Face of an Unchanging Gonadotropin-Releasing Hormone Pulse Frequency, The Journal of Clinical Endocrinology and Metabolism, vol.79, issue.3, pp.858-64, 1994.

,

G. Ahlborg, L. Axelsson, and . Bodin, Shift Work, Nitrous Oxide Exposure and Subfertility among Swedish Midwives, International Journal of Epidemiology, vol.25, issue.4, pp.783-90, 1996.

J. Alleva, M. Waleski, F. R-alleva, and E. Umberger, Synchronizing Effect of Photoperiodicity on Ovulation in Hamsters, Endocrinology, vol.82, issue.6, pp.1227-1262, 1968.

,

. Alvarez-garcía, A. Virginia, C. González, C. Martínez-campa, S. Alonso-gonzález et al., Melatonin Modulates Aromatase Activity and Expression in Endothelial Cells, Oncology Reports, vol.29, issue.5, pp.2058-64, 2013.

,

C. Ancel, H. Agnete, M. Bentsen, M. Sébert, J. D. Tena-sempere et al., Stimulatory Effect of RFRP-3 on the Gonadotrophic Axis in the Male Syrian Hamster: The Exception Proves the Rule, Endocrinology, vol.153, issue.3, pp.1352-63, 2012.

C. Ancel, M. A. Inglis, and G. M. Anderson, Central RFRP-3 Stimulates LH Secretion in Male Mice and Has Cycle Stage-Dependent Inhibitory Effects in Females, Endocrinology, vol.158, issue.9, pp.2873-83, 2017.

E. Angelopoulou, C. Quignon, L. J. Kriegsfeld, and V. Simonneaux, Functional Implications of RFRP-3 in the Central Control of Daily and Seasonal Rhythms in Reproduction, Frontiers in Endocrinology, vol.10, p.183, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02390075

,

L. Ansel, . Bolborea, P. A-h-bentsen, J. Klosen, V. D-mikkelsen et al., Differential Regulation of Kiss1 Expression by Melatonin and Gonadal Hormones in Male and Female Syrian Hamsters, Journal of Biological Rhythms, vol.25, issue.2, pp.81-91, 2010.

,

R. Armstrong, R. M. Anne, R. Reynolds, C. H. Leask, . Shearing et al., Decreased Serum Levels of Kisspeptin in Early Pregnancy Are Associated with Intra-Uterine Growth Restriction and Pre-Eclampsia, Prenatal Diagnosis, vol.29, issue.10, pp.982-85, 2009.

J. Arreguin-arevalo, . Alejandro, A. Clay, . Lents, A. Todd et al., KiSS-1 Peptide Induces Release of LH by a Direct Effect on the Hypothalamus of Ovariectomized Ewes, Animal Reproduction Science, vol.101, issue.3-4, pp.265-75, 2007.

M. Attarchi, H. Darkhi, M. Khodarahmian, M. Dolati, M. Kashanian et al., Characteristics of Menstrual Cycle in Shift Workers, Global Journal of Health Science, vol.5, issue.3, pp.163-72, 2013.

C. R. Austin, Ovulation, Fertilization, and Early Cleavage in the Hamster (Mesocricetus Auratus), Journal. Royal Microscopical Society (Great Britain), vol.75, issue.3, pp.141-54, 1956.

G. Axelsson, L. Ahlborg, and . Bodin, Shift Work, Nitrous Oxide Exposure, and Spontaneous Abortion among Swedish Midwives, Occupational and Environmental Medicine, vol.53, issue.6, pp.374-78, 1996.

T. Bahougne, E. Angelopoulou, N. Jeandidier, and V. Simonneaux, Individual Evaluation of Luteinizing Hormone in Aged C57BL/6 J Female Mice, 2019.
URL : https://hal.archives-ouvertes.fr/hal-02390065

O. Geroscience,

M. Bailey and R. Silver, Sex Differences in Circadian Timing Systems: Implications for Disease, vol.35, pp.111-150, 2014.

,

. Beaulé, J. W. Christian, P. T. Mitchell, R. Lindberg, L. E. Damadzic et al., Temporally Restricted Role of Retinal PACAP: Integration of the Phase-Advancing Light Signal to the SCN, Journal of Biological Rhythms, vol.24, issue.2, pp.126-160, 2009.

E. Beek, H. M-van-der, V. Swarts, and . Wiegant, Central Administration of Antiserum to Vasoactive Intestinal Peptide Delays and Reduces Luteinizing Hormone and Prolactin Surges in Ovariectomized, Estrogen-Treated Rats, Neuroendocrinology, vol.69, issue.4, pp.227-264, 1999.

E. Beek, V. M-van-der, H. Wiegant, . A-van-der-donk, . Van-den et al., Lesions of the Suprachiasmatic Nucleus Indicate the Presence of a Direct Vasoactive Intestinal Polypeptide-Containing Projection to Gonadotrophin-Releasing Hormone Neurons in the Female Rat, Journal of Neuroendocrinology, vol.5, issue.2, pp.137-181, 1993.

D. M. Berson, F. A. Dunn, and M. Takao, Phototransduction by Retinal Ganglion Cells That Set the Circadian Clock, Science, vol.295, issue.5557, pp.1070-73, 2002.

H. Bøggild and . Knutsson, Shift Work, Risk Factors and Cardiovascular Disease, Scandinavian Journal of Work, vol.25, issue.2, pp.85-99, 1999.

D. B. Boivin, M. Geneviève, F. O. Tremblay, and . James, Working on Atypical Schedules, Sleep Medicine, vol.8, issue.6, pp.578-89, 2007.

J. Bonde, J. Peter, H. A. Hansen, S. Kolstad, . Mikkelsen et al., Work at Night and Breast Cancer--Report on Evidence-Based Options for Preventive Actions, Scandinavian Journal of Work, vol.38, issue.4, pp.380-90, 2012.

J. Bonde, K. T. Peter, M. Jørgensen, K. Bonzini, and . Palmer, Miscarriage and Occupational Activity: A Systematic Review and Meta-Analysis Regarding Shift Work, Working Hours, Lifting, Standing, and Physical Workload, Scandinavian Journal of Work, vol.39, issue.4, pp.325-359, 2013.

,

M. A. Bosch, J. Karen, O. Tonsfeldt, and . Rønnekleiv, MRNA Expression of Ion Channels in GnRH Neurons: Subtype-Specific Regulation by 17?-Estradiol, Molecular and Cellular Endocrinology, vol.367, issue.1-2, pp.85-97, 2013.

,

J. Bouligand, C. Ghervan, J. A. Tello, S. Brailly-tabard, S. Salenave et al., Anne Guiochon-Mantel, p.1, 2009.

, Mutation, The New England Journal of Medicine, vol.360, issue.26, pp.2742-2790

,

M. Bracci, N. Manzella, A. Copertaro, S. Staffolani, E. Strafella et al.,

L. Santarelli, Rotating-Shift Nurses after a Day off: Peripheral Clock Gene Expression, Urinary Melatonin, and Serum 17-?-Estradiol Levels, Scandinavian Journal of Work, vol.40, issue.3, pp.295-304, 2014.

O. Breuer, M. Abdulhadi-atwan, S. Zeligson, H. Fridman, P. Renbaum et al., A Novel Severe N-Terminal Splice Site KISS1R Gene Mutation Causes Hypogonadotropic Hypogonadism but Enables a Normal Development of Neonatal External Genitalia, European Journal of Endocrinology / European Federation of Endocrine Societies, vol.167, issue.2, pp.209-225, 2012.

,

F. Brioude, J. Bouligand, B. Francou, J. Fagart, R. Roussel et al., Two Families with Normosmic Congenital Hypogonadotropic Hypogonadism and Biallelic Mutations in KISS1R (KISS1 Receptor): Clinical Evaluation and Molecular Characterization of a Novel Mutation, PLoS ONE, vol.8, issue.1, p.53896, 2013.

,

F. H. Bronson and F. Saal, Control of the Preovulatory Release of Luteinizing Hormone by Steroids in the Mouse, Endocrinology, vol.104, issue.5, pp.1247-55, 1979.

,

K. Brown-grant and G. Raisman, Abnormalities in Reproductive Function Associated with the Destruction of the Suprachiasmatic Nuclei in Female Rats, Proceedings of the Royal Society of London. Series B, vol.198, pp.279-96, 1132.

,

J. B. Brown, Types of Ovarian Activity in Women and Their Significance: The Continuum (a Reinterpretation of Early Findings), Human Reproduction Update, vol.17, issue.2, pp.141-58, 2011.

D. Cahill, P. Wardle, C. Harlow, and M. Hull, Onset of the Preovulatory Luteinizing Hormone Surge: Diurnal Timing and Critical Follicular Prerequisites, Fertility and Sterility, vol.70, issue.1, pp.56-59, 1998.

M. Calder, Y. Chan, R. Raj, M. Pampillo, A. Elbert et al., Implantation Failure in Female Kiss1-/-Mice Is Independent of Their Hypogonadic State and Can Be Partially Rescued by Leukemia Inhibitory Factor, Endocrinology, vol.155, issue.8, pp.3065-78, 2014.

A. Caraty, . Smith, . Lomet, . Ben-saïd, J. Morrissey et al., Kisspeptin Synchronizes Preovulatory Surges in Cyclical Ewes and Causes Ovulation in Seasonally Acyclic Ewes, Endocrinology, vol.148, issue.11, pp.5258-67, 2007.
URL : https://hal.archives-ouvertes.fr/hal-02657423

T. Carreón, M. J. Hein, K. W. Hanley, S. M. Viet, and A. Ruder, Coronary Artery Disease and Cancer Mortality in a Cohort of Workers Exposed to Vinyl Chloride, Carbon Disulfide, Rotating Shift Work, and o-Toluidine at a Chemical Manufacturing Plant, American Journal of Industrial Medicine, vol.57, issue.4, pp.398-411, 2014.

,

J. E. Cartwright and P. J. Williams, Altered Placental Expression of Kisspeptin and Its Receptor in Pre-Eclampsia, The Journal of Endocrinology, vol.214, issue.1, pp.79-85, 2012.

O. Castanon-cervantes, M. Wu, K. Christopher-ehlen, K. L. Paul, . Gamble et al., Dysregulation of Inflammatory Responses by Chronic Circadian Disruption, Journal of Immunology, vol.185, issue.10, pp.5796-5805, 1950.

,

. Cázarez-márquez, S. Fernando, M. Milesi, P. Laran-chich, and . Klosen, Kisspeptin and RFRP3 Modulate Body Mass in Phodopus Sungorus via Two Different Neuroendocrine Pathways, Journal of Neuroendocrinology, vol.31, issue.4, 2019.

A. Cetkovi?, D. Miljic, A. Ljubi?, M. Patterson, M. Ghatei et al., Plasma Kisspeptin Levels in Pregnancies with Diabetes and Hypertensive Disease as a Potential Marker of Placental Dysfunction and Adverse Perinatal Outcome, Endocrine Research, vol.37, issue.2, pp.78-88, 2012.

J. P. Chan, V. F. Butler, N. E. Sidhoum, S. B. Pinnell, and . Seminara, Kisspeptin Administration to Women: A Window into Endogenous Kisspeptin Secretion and GnRH Responsiveness across the Menstrual Cycle, The Journal of Clinical Endocrinology and Metabolism, vol.97, issue.8, pp.1458-67, 2012.

Y. M. Chan, S. Broder-fingert, K. M. Wong, and S. B. Seminara, Kisspeptin/Gpr54-Independent Gonadotrophin-Releasing Hormone Activity in Kiss1 and Gpr54 Mutant Mice, Journal of Neuroendocrinology, vol.21, issue.12, pp.1015-1038, 2009.

D. Chassard, I. Bur, V. Poirel, J. Mendoza, and V. Simonneaux, Evidence for a Putative Circadian Kiss-Clock in the Hypothalamic AVPV in Female Mice, Endocrinology, 2015.

J. Chen, Y. Lin, and S. Hsiao, Obesity and High Blood Pressure of 12-Hour Night Shift Female Clean-Room Workers, Chronobiology International, vol.27, issue.2, pp.334-378, 2010.

R. Y. Cheong, R. Porteous, P. Chambon, I. Abrahám, and A. E. Herbison, Effects of Neuron-Specific Estrogen Receptor (ER) ? and ER? Deletion on the, 2014.

, Acute Estrogen Negative Feedback Mechanism in Adult Female Mice, Endocrinology, vol.155, issue.4, pp.1418-1445

L. Chevrier, F. Guimiot, and N. De-roux, GnRH Receptor Mutations in Isolated Gonadotropic Deficiency, Molecular and Cellular Endocrinology, vol.346, issue.1-2, pp.21-28, 2011.

,

H. K. Choe, H. Kim, S. H. Park, H. Lee, J. Park et al., Synchronous Activation of Gonadotropin-Releasing Hormone, 2013.

, Gene Transcription and Secretion by Pulsatile Kisspeptin Stimulation, Proceedings of the National Academy of Sciences, vol.110, issue.14, pp.5677-82

,

C. A. Christian, J. L. Mobley, and S. M. Moenter, Diurnal and Estradiol-Dependent Changes in Gonadotropin-Releasing Hormone Neuron Firing Activity, Proceedings of the National Academy of Sciences of the United States of America, vol.102, issue.43, pp.15682-87, 2005.

C. A. Christian and S. M. Moenter, Critical Roles for Fast Synaptic Transmission in Mediating Estradiol Negative and Positive Feedback in the Neural Control of Ovulation, Endocrinology, vol.149, issue.11, pp.5500-5508, 2008.

,

A. Chryssikopoulos, C. Gregoriou, C. Papadias, and . Loghis, Gonadotropin Ovulation Induction and Pregnancies in Women with Kallmann's Syndrome, Gynecological Endocrinology : The Official Journal of the International Society of Gynecological Endocrinology, vol.12, issue.2, pp.103-111, 1998.

A. Chu, L. Zhu, D. Ian, O. Blum, A. Mai et al., Global but Not Gonadotrope-Specific Disruption of Bmal1 Abolishes the Luteinizing Hormone Surge without Affecting Ovulation, Endocrinology, vol.154, issue.8, pp.2924-2959, 2013.

J. Chu, M. A. Andrade, S. M. Shupnik, and . Moenter, Differential Regulation of Gonadotropin-Releasing Hormone Neuron Activity and Membrane Properties by Acutely Applied Estradiol: Dependence on Dose and Estrogen Receptor Subtype, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.29, issue.17, pp.5616-5643, 2009.

F. Chung, C. Yao, and G. Wan, The Associations between Menstrual Function and Life Style/Working Conditions among Nurses in Taiwan, Journal of Occupational Health, vol.47, issue.2, pp.149-56, 2005.

I. Clarke, J. Cummins, M. Crowder, and T. Nett, Long-Term Negative Feedback Effects of Oestrogen and Progesterone on the Pituitary Gland of the Long-Term Ovariectomized Ewe, The Journal of Endocrinology, vol.120, issue.2, pp.207-221, 1989.

X. Clarkson, W. Anglemont-de-tassigny, . Colledge, A. Caraty, and . Herbison, Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain, Journal of Neuroendocrinology, vol.21, issue.8, pp.673-82, 2009.
URL : https://hal.archives-ouvertes.fr/hal-02666598

A. E. Clarkson and . Herbison, Postnatal Development of Kisspeptin Neurons in Mouse Hypothalamus; Sexual Dimorphism and Projections to Gonadotropin-Releasing Hormone Neurons, Endocrinology, vol.147, issue.12, pp.5817-5842, 2006.

J. E. Cone, L. Vaughan, S. Huete, and . Samuels, Reproductive Health Outcomes among Female Flight Attendants: An Exploratory Study, Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine, vol.40, issue.3, pp.210-226, 1998.

. Cordina-duverger, M. Émilie, N. Houot, M. E. Tvardik, C. Yamani et al., Prevalence of Night Work in France: Characterization from a Job-Exposure Matrix, Bulletin Épidémiologique Hebdomadaire N°, vol.8, issue.9, pp.168-74, 2018.

S. Cos, C. Martínez-campa, M. D. Mediavilla, and E. J. Sánchez-barceló, Melatonin Modulates Aromatase Activity in MCF-7 Human Breast Cancer Cells, Journal of Pineal Research, vol.38, issue.2, pp.136-178, 2005.

W. F. Crowley and J. Mcarthur, Simulation of the Normal Menstrual Cycle in Kallman's Syndrome by Pulsatile Administration of Luteinizing Hormone-Releasing Hormone (LHRH), The Journal of Clinical Endocrinology and Metabolism, vol.51, issue.1, pp.173-75, 1980.

D. Cumming, L. Honoré, J. Scott, and K. Williams, The Late Luteal Phase in Infertile Women: Comparison of Simultaneous Endometrial Biopsy and Progesterone Levels, Fertility and Sterility, vol.43, issue.5, pp.715-734, 1985.

K. Czieselsky, M. Prescott, R. Porteous, P. Campos, J. Clarkson et al., Pulse and Surge Profiles of Luteinizing Hormone Secretion in the Mouse, Endocrinology, vol.157, issue.12, pp.4794-4802, 2016.

,

L. A. De-tassigny, . Fagg, B. L. Mark, W. H. Carlton, and . Colledge, Kisspeptin Can Stimulate Gonadotropin-Releasing Hormone (GnRH) Release by a Direct Action at GnRH Nerve Terminals, Endocrinology, vol.149, issue.8, pp.3926-3958, 2008.

,

A. Dalkin, D. Haisenleder, G. Ortolano, T. Ellis, and J. Marshall, The Frequency of Gonadotropin-Releasing-Hormone Stimulation Differentially Regulates Gonadotropin Subunit Messenger Ribonucleic Acid Expression, Endocrinology, vol.125, issue.2, pp.917-941, 1989.

,

A. J. Davidson, M. Sellix, . Daniel, M. Yamazaki, G. Menaker et al., Chronic Jet-Lag Increases Mortality in Aged Mice, Current Biology : CB, vol.16, issue.21, pp.914-920, 2006.

,

D. K. Davis, C. Mirick, F. Z. Chen, and . Stanczyk, Night Shift Work and Hormone Levels in Women, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, vol.21, issue.4, pp.609-627, 2012.

S. Davis, D. Mirick, and R. Stevens, Night Shift Work, Light at Night, and Risk of Breast Cancer, Journal of the National Cancer Institute, vol.93, issue.20, pp.1557-62, 2001.

H. Demirbilek, K. Nuri-ozbek, . Demir, Y. Damla-kotan, M. Cesur et al., Normosmic Idiopathic Hypogonadotropic Hypogonadism Due to a Novel Homozygous Nonsense c.C969A (p.Y323X) Mutation in the KISS1R Gene in Three Unrelated Families, Clinical Endocrinology, vol.82, issue.3, pp.429-467, 2015.

,

W. S. Dhillo, B. Owais, M. Chaudhri, E. L. Patterson, K. G. Thompson et al., Kisspeptin-54 Stimulates the Hypothalamic-Pituitary Gonadal Axis in Human Males, The Journal of Clinical Endocrinology and Metabolism, vol.90, issue.12, pp.6609-6624, 2005.

W. S. Dhillo, B. Owais, E. L. Chaudhri, K. G. Thompson, M. Murphy et al., Kisspeptin-54 Stimulates Gonadotropin Release Most Potently during the Preovulatory Phase of the Menstrual Cycle in Women, The Journal of Clinical Endocrinology and Metabolism, vol.92, issue.10, pp.3958-66, 2007.

J. Donato, R. M. Cravo, R. Frazão, L. Gautron, M. Michael et al., Leptin's Effect on Puberty in Mice Is Relayed by the Ventral Premammillary Nucleus and Does Not Require Signaling in Kiss1 Neurons, The Journal of Clinical Investigation, vol.121, issue.1, pp.355-68, 2011.

A. Donoso, C. Seltzer, R. Navarro, F. Cabrera, A. López et al., Brazilian Journal of Medical and Biological Research = Revista Brasileira de Pesquisas Médicas e Biológicas / Sociedade Brasileira de Biofísica, vol.27, pp.921-953, 1994.

A. A. Dorling, G. Martin, . Todman, S. Kenneth, A. E. Korach et al., Critical Role for Estrogen Receptor Alpha in Negative Feedback Regulation of Gonadotropin-Releasing Hormone MRNA Expression in the Female Mouse, Neuroendocrinology, vol.78, issue.4, pp.204-213, 2003.

R. Ecochard, H. Boehringer, M. Rabilloud, and H. Marret, Chronological Aspects of Ultrasonic, Hormonal, and Other Indirect Indices of Ovulation, BJOG : An International Journal of Obstetrics and Gynaecology, vol.108, issue.8, pp.822-851, 2001.

A. Endo and T. Watanabe, Effects of Non-24-Hour Days on Reproductive Efficacy and Embryonic Development in Mice, Gamete Research, vol.22, issue.4, pp.435-476, 1989.

,

O. Eyigor and L. Jennes, Identification of Glutamate Receptor Subtype MRNAs in Gonadotropin-Releasing Hormone Neurons in Rat Brain, Endocrine, vol.4, issue.2, pp.133-172, 1996.

,

M. Fatehi and Z. Fatehi-hassanabad, Effects of 17beta-Estradiol on Neuronal Cell Excitability and Neurotransmission in the Suprachiasmatic Nucleus of Rat, Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, vol.33, issue.6, pp.1354-64, 2008.

. Filardo, Epidermal Growth Factor Receptor (EGFR) Transactivation by Estrogen via the G-Protein-Coupled Receptor, GPR30: A Novel Signaling Pathway with Potential Significance for Breast Cancer, The Journal of Steroid Biochemistry and Molecular Biology, vol.80, issue.2, pp.231-269, 2002.

J. Filardo, K. Quinn, A. Bland, and . Frackelton, Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF, Molecular Endocrinology, vol.14, issue.10, pp.1649-60, 2000.

,

A. B. Francis, M. Abera, . Matjila, P. Robert, A. Millar et al., Kisspeptin Regulation of Genes Involved in Cell Invasion and Angiogenesis in First Trimester Human Trophoblast Cells, PloS One, vol.9, issue.6, p.99680, 2014.

,

J. M. Francl, G. Kaur, and J. Glass, Roles of Light and Serotonin in the Regulation of Gastrin-Releasing Peptide and Arginine Vasopressin Output in the, 2010.

. Hamster-scn-circadian and . Clock, The European Journal of Neuroscience, vol.32, issue.7, pp.1170-79

,

B. Francou, C. Paul, L. Amazit, A. Cartes, C. Bouvattier et al., Prevalence of KISS1 Receptor Mutations in a Series of 603 Patients with Normosmic Congenital Hypogonadotrophic Hypogonadism and Characterization of Novel Mutations: A Single-Centre Study, Human Reproduction, 2016.

K. E. Friend, Y. Chiou, M. Lopes, E. Laws, K. Hughes et al., Estrogen Receptor Expression in Human Pituitary: Correlation with Immunohistochemistry in Normal Tissue, and Immunohistochemistry and Morphology in Macroadenomas, The Journal of Clinical Endocrinology and Metabolism, vol.78, issue.6, pp.1497-1504, 1994.

P. Frost, H. A. Kolstad, and J. P. Bonde, Shift Work and the Risk of Ischemic Heart Disease -a Systematic Review of the Epidemiologic Evidence, Scandinavian Journal of Work, vol.35, issue.3, pp.163-79, 2009.

T. Funabashi, . Aiba, . Sano, F. Shinohara, and . Kimura, Intracerebroventricular Injection of Arginine-Vasopressin V1 Receptor Antagonist Attenuates the Surge of Luteinizing Hormone and Prolactin Secretion in Proestrous Rats, Neuroscience Letters, vol.260, issue.1, pp.37-40, 1999.

Y. Gan, C. Yang, X. Tong, H. Sun, Y. Cong et al., Shift Work and Diabetes Mellitus: A Meta-Analysis of Observational Studies, Occupational and Environmental Medicine, vol.72, issue.1, pp.72-78, 2015.

. García-galiano, D. David, . Van-ingen, S. Schenau, M. A. Leon et al., Kisspeptin Signaling Is Indispensable for Neurokinin B, but Not Glutamate, Stimulation of Gonadotropin Secretion in Mice, Endocrinology, vol.153, issue.1, pp.316-344, 2012.

,

J. George, R. Anderson, and R. Millar, Kisspeptin-10 Stimulation of Gonadotrophin Secretion in Women Is Modulated by Sex Steroid Feedback, Human Reproduction, vol.27, issue.12, pp.3552-59, 2012.

, Kisspeptin-10 Stimulation of Gonadotrophin Secretion in Women Is Modulated by Sex Steroid Feedback, Human Reproduction, vol.27, issue.12, pp.3552-59, 2012.

E. M. Gibson, S. A. Humber, S. Jain, P. Wilbur, S. Williams et al., Alterations in RFamide-Related Peptide Expression Are Coordinated with the Preovulatory Luteinizing Hormone Surge, Endocrinology, vol.149, issue.10, pp.4958-69, 2008.

M. U. Gillette and S. Reppert, The Hypothalamic Suprachiasmatic Nuclei: Circadian Patterns of Vasopressin Secretion and Neuronal Activity in Vitro, Brain Research Bulletin, vol.19, issue.1, pp.135-174, 1987.

B. Goichot, . Weibel, C. Chapotot, . Gronfier, G. Piquard et al., Effect of the Shift of the Sleep-Wake Cycle on Three Robust Endocrine Markers of the Circadian Clock, The American Journal of Physiology, vol.275, issue.2, pp.243-251, 1998.

E. B. Gold and E. Tomich, Occupational Hazards to Fertility and Pregnancy Outcome, Occupational Medicine, vol.9, issue.3, pp.435-69, 1994.

. Gómez-acebo, T. Inés, K. Dierssen-sotos, M. T. Papantoniou, M. F. García-unzueta et al., Association between Exposure to Rotating Night Shift versus Day Shift Using Levels of 6-Sulfatoxymelatonin and Cortisol and Other Sex Hormones in Women, Chronobiology International, pp.1-8, 2014.

L. Gordley, G. Lemasters, J. S-r-simpson, and . Yiin, Menstrual Disorders and Occupational, Stress, and Racial Factors among Military Personnel, Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine, vol.42, issue.9, pp.871-81, 2000.

M. Gottsch, J. Cunningham, . Smith, B. Popa, W. Acohido et al., A Role for Kisspeptins in the Regulation of Gonadotropin Secretion in the Mouse, Endocrinology, vol.145, issue.9, pp.4073-77, 2004.

,

M. L. Gottsch, M. Víctor, Z. Navarro, C. Zhao, J. Glidewell-kenney et al., Regulation of Kiss1 and Dynorphin Gene Expression in the Murine Brain by Classical and Nonclassical Estrogen Receptor Pathways, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.29, issue.29, pp.9390-95, 2009.

,

T. J. Greives, A. O. Mason, M. Scotti, J. Levine, E. D. Ketterson et al., Environmental Control of Kisspeptin: Implications for Seasonal Reproduction, Endocrinology, vol.148, issue.3, pp.1158-66, 2007.

,

E. Grimes, M. Taymor, and I. Thompson, Induction of Timed Ovulation with Synthetic Luteinizing Hormone-Releasing Hormone in Women Undergoing Insemination Therapy. I. Effect of a Single Parenteral Administration at Midcycle, Fertility and Sterility, vol.26, issue.3, pp.277-82, 1975.

A. Grundy, H. Richardson, I. Burstyn, C. Lohrisch, K. Sandip et al., Increased Risk of Breast Cancer Associated with Long-Term Shift Work in Canada, Occupational and Environmental Medicine, vol.70, issue.12, pp.831-869, 2013.

F. Gu, J. Han, F. Laden, A. Pan, N. E. Caporaso et al., Total and Cause-Specific Mortality of U.S. Nurses Working Rotating Night Shifts, American Journal of Preventive Medicine, vol.48, issue.3, pp.241-52, 2015.

,

E. Guermandi, M. Vegetti, . Bianchi, G. Uglietti, P. Ragni et al., Reliability of Ovulation Tests in Infertile Women, Obstetrics and Gynecology, vol.97, issue.1, pp.92-96, 2001.

K. A. Guerriero, L. Kim, . Keen, P. Robert, E. Millar et al., Developmental Changes in GnRH Release in Response to Kisspeptin Agonist and Antagonist in Female Rhesus Monkeys (Macaca Mulatta): Implication for the Mechanism of Puberty, Endocrinology, vol.153, issue.2, pp.825-861, 2012.

V. Gumenyuk, R. Howard, T. Roth, O. Korzyukov, and C. Drake, Sleep Loss, Circadian Mismatch, and Abnormalities in Reorienting of Attention in Night Workers with Shift Work Disorder, Sleep, vol.37, issue.3, pp.545-56, 2014.

,

T. L. Habermehl, K. C. Parkinson, G. B. Hubbard, Y. Ikeno, J. I. Engelmeyer et al., Extension of Longevity and Reduction of Inflammation Is Ovarian-Dependent, but Germ Cell-Independent in Post-Reproductive Female Mice, GeroScience, vol.41, issue.1, pp.25-38, 2019.

D. J. Haisenleder, A. C-dalkin, G. Ortolano, J. Marshall, and M. Shupnik, A Pulsatile Gonadotropin-Releasing Hormone Stimulus Is Required to Increase Transcription of the Gonadotropin Subunit Genes: Evidence for Differential Regulation of Transcription by Pulse Frequency in Vivo, Endocrinology, vol.128, issue.1, pp.509-526, 1991.

T. J. Haley and W. G. Mccormick, PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE, British Journal of Pharmacology and Chemotherapy, vol.12, issue.1, pp.12-15, 1957.

,

A. Hall, K. Taylor, J. Martin, D. Rivier, W. Schoenfeld et al., Decreased Release of Gonadotropin-Releasing Hormone during the Preovulatory Midcycle Luteinizing Hormone Surge in Normal Women, Proceedings of the National Academy of Sciences of the United States of America, vol.91, issue.15, pp.6894-98, 1994.

K. J. Hamilton, Y. Arao, and K. S. Korach, Estrogen Hormone Physiology: Reproductive Findings from Estrogen Receptor Mutant Mice, Reproductive Biology, vol.14, issue.1, pp.3-8, 2014.

S. Hampton, L. Morgan, . Lawrence, . Anastasiadou, . Norris et al., Postprandial Hormone and Metabolic Responses in Simulated Shift Work, The Journal of Endocrinology, vol.151, issue.2, pp.259-67, 1996.

. Han, M. L. Seong-kyu, K. J. Gottsch, . Lee, M. Simina et al., Activation of Gonadotropin-Releasing Hormone Neurons by Kisspeptin as a Neuroendocrine Switch for the Onset of Puberty, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.25, issue.49, pp.11349-56, 2005.

. Hansen, Increased Breast Cancer Risk among Women Who Work Predominantly at Night, Epidemiology, vol.12, issue.1, pp.74-77, 2001.

C. F. Hansen and . Lassen, Nested Case-Control Study of Night Shift Work and Breast Cancer Risk among Women in the Danish Military, Occupational and Environmental Medicine, vol.69, issue.8, pp.551-56, 2012.

S. D. Harlow and S. Ephross, Epidemiology of Menstruation and Its Relevance to Women's Health, Epidemiologic Reviews, vol.17, issue.2, pp.265-86, 1995.

S. D. Harlow and G. Matanoski, The Association between Weight, Physical Activity, and Stress and Variation in the Length of the Menstrual Cycle, American Journal of Epidemiology, vol.133, issue.1, pp.38-49, 1991.

S. D. Harlow and M. Park, A Longitudinal Study of Risk Factors for the Occurrence, Duration and Severity of Menstrual Cramps in a Cohort of College Women, British Journal of Obstetrics and Gynaecology, vol.103, issue.11, pp.1134-1176, 1996.

M. Hatch, S. Figa-talamanca, and . Salerno, Work Stress and Menstrual Patterns among American and Italian Nurses, Scandinavian Journal of Work, vol.25, issue.2, pp.144-50, 1999.

J. B. Henningsen, C. Ancel, J. D. Mikkelsen, F. Gauer, and V. Simonneaux, Roles of RFRP-3 in the Daily and Seasonal Regulation of Reproductive Activity in Female Syrian Hamsters, Endocrinology, vol.158, issue.3, pp.652-63, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02390110

,

. Herbison, Estrogen Positive Feedback to Gonadotropin-Releasing Hormone (GnRH) Neurons in the Rodent: The Case for the Rostral Periventricular Area of the Third Ventricle (RP3V), Brain Research Reviews, vol.57, issue.2, pp.277-87, 2008.

,

A. E. Herbison and D. Theodosis, Localization of Oestrogen Receptors in Preoptic Neurons Containing Neurotensin but Not Tyrosine Hydroxylase, Cholecystokinin or Luteinizing Hormone-Releasing Hormone in the Male and Female Rat, Neuroscience, vol.50, issue.2, pp.283-98, 1992.

J. Hermansson, K. Gillander-gådin, B. Karlsson, C. Reuterwall, J. Hallqvist et al., Case Fatality of Myocardial Infarction among Shift Workers, International Archives of Occupational and Environmental Health, vol.88, issue.5, pp.599-605, 2015.

S. M. Hill, P. Victoria, R. T. Belancio, S. Dauchy, S. Xiang et al., Melatonin: An Inhibitor of Breast Cancer, Endocrine-Related Cancer, 2015.

G. E. Hoffman, W. W. Le, I. Franceschini, A. Caraty, and J. P. Advis, Expression of Fos and in Vivo Median Eminence Release of LHRH Identifies an Active Role for Preoptic Area Kisspeptin Neurons in Synchronized Surges of LH and LHRH in the Ewe, Endocrinology, vol.152, issue.1, pp.214-236, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01129495

Y. Horikoshi, H. Matsumoto, Y. Takatsu, T. Ohtaki, C. Kitada et al., Dramatic Elevation of Plasma Metastin Concentrations in Human Pregnancy: Metastin as a Novel Placenta-Derived Hormone in Humans, The Journal of Clinical Endocrinology and Metabolism, vol.88, issue.2, pp.914-933, 2003.

,

G. Horst, M. T-van-der, . Muijtjens, . Kobayashi, . Takano et al., Mammalian Cry1 and Cry2 Are Essential for Maintenance of Circadian Rhythms, Nature, vol.398, issue.6728, pp.627-657, 1999.

T. Horvath, E. Cela, . Van-der, and . Beek, Gender-Specific Apposition between Vasoactive Intestinal Peptide-Containing Axons and Gonadotrophin-Releasing Hormone-Producing Neurons in the Rat, Brain Research, vol.795, issue.1-2, pp.277-81, 1998.

. Hrabovszky, Neuroanatomy of the Human Hypothalamic Kisspeptin System, Neuroendocrinology, vol.99, issue.1, pp.33-48, 2014.

P. Hrabovszky, . Ciofi, M. Vida, E. Horvath, . Keller et al., The Kisspeptin System of the Human Hypothalamus: Sexual Dimorphism and Relationship with Gonadotropin-Releasing Hormone and Neurokinin B Neurons, The European Journal of Neuroscience, vol.31, issue.11, pp.1984-98, 2010.
URL : https://hal.archives-ouvertes.fr/hal-01129444

I. Hrabovszky, N. Kalló, É. Szlávik, I. Keller, Z. Merchenthaler et al., Gonadotropin-Releasing Hormone Neurons Express Estrogen Receptor-?, The Journal of Clinical Endocrinology & Metabolism, vol.92, issue.7, pp.2827-2857, 2007.

,

L. Huijbregts and N. De-roux, KISS1 Is Down-Regulated by 17beta-Estradiol in MDA-MB-231 Cells through a Nonclassical Mechanism and Loss of Ribonucleic Acid Polymerase II Binding at the Proximal Promoter, Endocrinology, vol.151, issue.8, pp.3764-72, 2010.

,

M. Hull, P. Savage, D. R-bromham, A. Ismail, and A. Morris, The Value of a Single Serum Progesterone Measurement in the Midluteal Phase as a Criterion of a Potentially Fertile Cycle ('ovulation') Derived Form Treated and Untreated Conception Cycles, Fertility and Sterility, vol.37, issue.3, pp.355-60, 1982.

. Iarc, Monographs Programme Finds Cancer Hazards Associated with Shiftwork, Painting and Firefighting, International Agency for Research on Cancer, 2007.

. Iliodromiti, R. A. Stamatina, S. M. Anderson, and . Nelson, Technical and Performance Characteristics of Anti-Müllerian Hormone and Antral Follicle Count as Biomarkers of Ovarian Response, Human Reproduction Update, vol.21, issue.6, pp.698-710, 2015.

,

N. Inoue, K. Sasagawa, K. Ikai, Y. Sasaki, J. Tomikawa et al., Kisspeptin Neurons Mediate Reflex Ovulation in the Musk Shrew (Suncus Murinus), Proceedings of the National Academy of Sciences of the United States of America, vol.108, issue.42, pp.17527-17559, 2011.

M. S. Irwig, S. Gregory, J. T. Fraley, . Smith, V. Blake et al., Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 MRNA in the Male Rat, Neuroendocrinology, vol.80, issue.4, pp.264-72, 2004.

,

J. S. Jacobi, C. Martin, G. Nava, C. Michael, C. Jeziorski et al., 17-Beta-Estradiol Directly Regulates the Expression of Adrenergic Receptors and Kisspeptin/GPR54 System in GT1-7 GnRH Neurons, Neuroendocrinology, vol.86, issue.4, pp.260-69, 2007.

A. Jayasena, A. N. Abbara, . Comninos, M. Gurjinder, G. Nijher et al., , 2014.

, Triggers Egg Maturation in Women Undergoing in Vitro Fertilization, The Journal of Clinical Investigation, vol.124, issue.8, pp.3667-77

A. Jayasena, G. N-comninos, . Nijher, D. Abbara, J. Silva et al., Twice-Daily Subcutaneous Injection of Kisspeptin-54 Does Not Abolish Menstrual Cyclicity in Healthy Female Volunteers, The Journal of Clinical Endocrinology and Metabolism, vol.98, issue.11, pp.4464-74, 2013.

A. Jayasena, J. N-comninos, S. Veldhuis, . Misra, . Abbara et al., , 2013.

, Temporarily Increases Luteinizing Hormone Pulsatility in Healthy Women, Clinical Endocrinology, vol.79, issue.4, pp.558-63

A. N. Jayasena, S. Comninos, S. Narayanaswamy, A. Bhalla, Z. Abbara et al.,

S. Waljit and . Dhillo, Acute and Chronic Effects of Kisspeptin-54 Administration on GH, Prolactin and TSH Secretion in Healthy Women, Clinical Endocrinology, vol.81, issue.6, pp.891-98, 2014.

G. Jayasena, . Nijher, K. Abbara, . Murphy, . Lim et al., Twice-Weekly Administration of Kisspeptin-54 for 8 Weeks Stimulates Release of Reproductive Hormones in Women with Hypothalamic Amenorrhea, Clinical Pharmacology and Therapeutics, vol.88, issue.6, pp.840-887, 2010.

G. Jayasena, . Nijher, B. Owais, K. G. Chaudhri, A. Murphy et al., Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women with Hypothalamic Amenorrhea, but Chronic Administration Causes Tachyphylaxis, The Journal of Clinical Endocrinology and Metabolism, vol.94, issue.11, pp.4315-4338, 2009.

G. Jayasena, A. N. Nijher, A. Comninos, A. Abbara, M. L. Januszewki et al., The Effects of Kisspeptin-10 on Reproductive Hormone Release Show Sexual Dimorphism in Humans, The Journal of Clinical Endocrinology and Metabolism, vol.96, issue.12, pp.1963-72, 2011.

,

X. Jin, L. Shearman, D. Weaver, M. Zylka, G. Vries et al., A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock, Cell, vol.96, issue.1, pp.57-68, 1999.

A. M. Jukic, C. R. Zaura, A. J. Weinberg, R. Wilcox, P. Mcconnaughey et al., Accuracy of Reporting of Menstrual Cycle Length, American Journal of Epidemiology, vol.167, issue.1, pp.25-33, 2008.

H. Kadokawa, . Matsui, . Hayashi, C. Matsunaga, T. Kawashima et al., Peripheral Administration of Kisspeptin-10 Increases Plasma Concentrations of GH as Well as LH in Prepubertal Holstein Heifers, The Journal of Endocrinology, vol.196, issue.2, pp.331-365, 2008.

H. Kadokawa, T. Suzuki, and . Hashizume, Kisspeptin-10 Stimulates the Secretion of Growth Hormone and Prolactin Directly from Cultured Bovine Anterior Pituitary Cells, Animal Reproduction Science, vol.105, issue.3-4, pp.404-412, 2008.

,

U. B. Kaiser, . Jakubowiak, W. Steinberger, and . Chin, Differential Effects of Gonadotropin-Releasing Hormone (GnRH) Pulse Frequency on Gonadotropin Subunit and GnRH Receptor Messenger Ribonucleic Acid Levels in Vitro, Endocrinology, vol.138, issue.3, pp.1224-1255, 1997.

A. Kalsbeek, M. Buijs, C. Engelmann, R. Wotjak, and . Landgraf, In Vivo Measurement of a Diurnal Variation in Vasopressin Release in the Rat Suprachiasmatic Nucleus, Brain Research, vol.682, issue.1-2, pp.75-82, 1995.

A. S. Kauffman, M. L. Gottsch, J. Roa, A. C. Byquist, A. Crown et al., Sexual Differentiation of Kiss1 Gene Expression in the Brain of the Rat, Endocrinology, vol.148, issue.4, pp.1774-83, 2007.

S. Kavvasoglu, Z. Sema-ozkan, B. Kumbak, M. S?msek, and N. Ilhan, Association of Kisspeptin-10 Levels with Abortus Imminens: A Preliminary Study, Archives of Gynecology and Obstetrics, vol.285, issue.3, pp.649-53, 2012.

. Kawakami, K. Shin-ichi, M. Hirunagi, H. Ichikawa, K. Tsukamura et al., Evidence for Terminal Regulation of GnRH Release by Excitatory Amino Acids in the Median Eminence in Female Rats: A Dual Immunoelectron Microscopic Study, Endocrinology, vol.139, issue.3, pp.1458-61, 1998.

K. L. Keen, H. Frederick, . Wegner, R. Stephen, . Bloom et al., An Increase in Kisspeptin-54 Release Occurs with the Pubertal Increase in Luteinizing Hormone-Releasing Hormone-1 Release in the Stalk-Median Eminence of Female Rhesus Monkeys in Vivo, Endocrinology, vol.149, issue.8, pp.4151-57, 2008.

,

B. Kerdelhué, S. Brown, V. Lenoir, G. S. John-t-queenan, R. Jones et al., Timing of Initiation of the Preovulatory Luteinizing Hormone Surge and Its Relationship with the Circadian Cortisol Rhythm in the Human, Neuroendocrinology, vol.75, issue.3, pp.158-63, 2002.

A. R. Khan and A. Kauffman, The Role of Kisspeptin and RFamide-Related Peptide-3 Neurones in the Circadian-Timed Preovulatory Luteinising Hormone Surge, Journal of Neuroendocrinology, vol.24, issue.1, pp.131-174, 2012.

M. Kiyokawa, T. Matsuzaki, T. Iwasa, R. Ogata, M. Murakami et al., Neuropeptide Y Mediates Orexin A-Mediated Suppression of Pulsatile Gonadotropin-Releasing Hormone Secretion in Ovariectomized Rats, The Journal of Medical Investigation : JMI, vol.58, issue.1-2, pp.11-18, 2011.

U. Klenke, S. Constantin, and S. Wray, Neuropeptide Y Directly Inhibits Neuronal Activity in a Subpopulation of Gonadotropin-Releasing Hormone-1 Neurons via Y1 Receptors, Endocrinology, vol.151, issue.6, pp.2736-2782, 2010.

,

E. Knobil, T. Plant, P. Wildt, G. Belchetz, and . Marshall, Control of the Rhesus Monkey Menstrual Cycle: Permissive Role of Hypothalamic Gonadotropin-Releasing Hormone, Science, vol.207, issue.4437, pp.1371-73, 1980.

A. Knutsson, L. Alfredsson, T. Berndt-karlsson, E. I. Akerstedt, P. Fransson et al., Breast Cancer among Shift Workers: Results of the WOLF Longitudinal Cohort Study, Scandinavian Journal of Work, vol.39, issue.2, pp.170-77, 2013.

H. Kolstad, N. Bonde, T. Hjøllund, T. Jensen, E. Henriksen et al., Menstrual Cycle Pattern and Fertility: A Prospective Follow-up Study of Pregnancy and Early Embryonal Loss in 295 Couples Who Were Planning Their First Pregnancy, Fertility and Sterility, vol.71, issue.3, pp.490-96, 1999.

C. Kopp, V. Ressel, E. Wigger, and I. Tobler, Influence of Estrus Cycle and Ageing on Activity Patterns in Two Inbred Mouse Strains, Behavioural Brain Research, vol.167, issue.1, pp.165-74, 2006.

L. Kovanen, T. Sirkku, A. Saarikoski, J. Aromaa, T. Lönnqvist et al., ARNTL (BMAL1) and NPAS2 Gene Variants Contribute to Fertility and Seasonality, PloS One, vol.5, issue.4, 2010.

K. Krajnak, M. L-kashon, K. Rosewell, and P. Wise, Aging Alters the Rhythmic Expression of Vasoactive Intestinal Polypeptide MRNA but Not Arginine Vasopressin MRNA in the Suprachiasmatic Nuclei of Female Rats, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.18, issue.12, pp.4767-74, 1998.

,

J. Krege, J. B-hodgin, J. Couse, E. Enmark, J. Warner et al., Generation and Reproductive Phenotypes of Mice Lacking Estrogen Receptor Beta, Proceedings of the National Academy of Sciences of the United States of America, vol.95, issue.26, pp.15677-82, 1998.

,

L. J. Kriegsfeld, D. F. Mei, G. E. Bentley, T. Ubuka, A. O. Mason et al., Identification and Characterization of a Gonadotropin-Inhibitory System in the Brains of Mammals, Proceedings of the National Academy of Sciences of the United States of America, vol.103, issue.7, pp.2410-2425, 2006.

J. A. Krizo and E. M. Mintz, Sex Differences in Behavioral Circadian Rhythms in Laboratory Rodents, Frontiers in Endocrinology, vol.5, p.234, 2014.

S. Labyak, S. Lava, F. Turek, and P. Zee, Effects of Shiftwork on Sleep and Menstrual Function in Nurses, Health Care for Women International, vol.23, issue.6-7, pp.703-717, 2002.

A. Lakati, C. Binns, and M. Stevenson, The Effect of Work Status on Exclusive Breastfeeding in Nairobi, Asia-Pacific Journal of Public Health / Asia-Pacific Academic Consortium for Public Health, vol.14, issue.2, pp.85-90, 2002.

F. Lanfranco, J. Gromoll, . Sigrid-von-eckardstein, M. Eva, E. Herding et al., Role of Sequence Variations of the GnRH Receptor and G Protein-Coupled Receptor 54 Gene in Male Idiopathic Hypogonadotropic Hypogonadism, European Journal of Endocrinology, vol.153, issue.6, pp.845-52, 2005.

,

R. Lapatto, D. Carl-pallais, Y. Zhang, A. Chan, F. Mahan et al., Kiss1-/-Mice Exhibit More Variable Hypogonadism than Gpr54-/-Mice, Endocrinology, vol.148, issue.10, pp.4927-4963, 2007.

L. Lauria, T. J. Ballard, M. Caldora, C. Mazzanti, and A. Verdecchia, Reproductive Disorders and Pregnancy Outcomes among Female Flight Attendants, Aviation, Space, and Environmental Medicine, vol.77, issue.5, pp.533-572, 2006.

C. C. Lawson, E. A. Whelan, E. Hibert, D. Spiegelman, S. Eva et al., Rotating Shift Work and Menstrual Cycle Characteristics, Epidemiology, vol.22, issue.3, pp.305-317, 2011.

,

J. Lee, M. E-miele, D. Hicks, K. Phillips, J. Trent et al., KiSS-1, a Novel Human Malignant Melanoma Metastasis-Suppressor Gene, Journal of the National Cancer Institute, vol.88, issue.23, pp.1731-1768, 1996.

S. Legan, G. Coon, and F. Karsch, Role of Estrogen as Initiator of Daily LH Surges in the Ovariectomized Rat, Endocrinology, vol.96, issue.1, pp.50-56, 1975.

M. Lehman, . Silver, R. W-r-gladstone, M. Kahn, E. Gibson et al., Circadian Rhythmicity Restored by Neural Transplant. Immunocytochemical Characterization of the Graft and Its Integration with the Host Brain, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.7, issue.6, pp.1626-1664, 1987.

S. León, D. García-galiano, F. Ruiz-pino, A. Barroso, M. Manfredi-lozano et al., Physiological Roles of Gonadotropin-Inhibitory Hormone Signaling in the Control of Mammalian Reproductive Axis: Studies in the NPFF1 Receptor Null Mouse, Endocrinology, vol.155, issue.8, pp.2953-65, 2014.

,

. Leranth, N. J. Csaba, H. Maclusky, M. Sakamoto, F. Shanabrough et al., Glutamic Acid Decarboxylase-Containing Axons Synapse on LHRH Neurons in the Rat Medial Preoptic Area, Neuroendocrinology, vol.40, issue.6, pp.536-575, 1985.

,

C. Lima, S. Cardoso, E. Lemos, E. Zingler, C. Capanema et al., Mutational Analysis of the Genes Encoding RFamide-Related Peptide-3, the Human Orthologue of Gonadotrophin-Inhibitory Hormone, and Its Receptor (GPR147) in Patients with Gonadotrophin-Releasing Hormone-Dependent Pubertal Disorders, Journal of Neuroendocrinology, vol.26, issue.11, pp.817-841, 2014.

R. W. Logan, C. Zhang, S. Murugan, O. Stephanie, D. Connell et al., Chronic Shift-Lag Alters the Circadian Clock of NK Cells and Promotes Lung Cancer Growth in Rats, Journal of Immunology, vol.188, issue.6, pp.2583-91, 1950.

J. J. Logie, C. Fiona, . Denison, C. Simon, T. Riley et al., Evaluation of Kisspeptin Levels in Obese Pregnancy as a Biomarker for Pre-Eclampsia, Clinical Endocrinology, vol.76, issue.6, pp.887-93, 2012.

,

P. N. Lohstroh, J. Chen, J. Ba, L. M. Ryan, X. Xu et al., Bone Resorption Is Affected by Follicular Phase Length in Female Rotating Shift Workers, Environmental Health Perspectives, vol.111, issue.4, pp.618-640, 2003.

G. W. Louis, M. Greenwald-yarnell, R. Phillips, M. Lique, . Coolen et al., Molecular Mapping of the Neural Pathways Linking Leptin to the Neuroendocrine Reproductive Axis, Endocrinology, vol.152, issue.6, pp.2302-2312, 2011.

P. L. Lowrey and J. Takahashi, Genetics of Circadian Rhythms in Mammalian Model Organisms, Advances in Genetics, vol.74, pp.175-230, 2011.

,

E. Luo, B. Shannon, S. Stephens, N. Chaing, A. S. Munaganuru et al., Corticosterone Blocks Ovarian Cyclicity and the LH Surge via Decreased Kisspeptin Neuron Activation in Female Mice, Endocrinology, 2015.

R. M. Luque, J. Córdoba-chacón, D. Manuel, . Gahete, M. Víctor et al., Kisspeptin Regulates Gonadotroph and Somatotroph Function in Nonhuman Primate Pituitary via Common and Distinct Signaling Mechanisms, Endocrinology, vol.152, issue.3, pp.957-66, 2011.

,

K. E. Lynch, L. Sunni, K. C. Mumford, B. W. Schliep, . Whitcomb et al., Assessment of Anovulation in Eumenorrheic Women: Comparison of Ovulation Detection Algorithms, Fertility and Sterility, vol.102, issue.2, pp.511-518, 2014.

C. E. Malcolm and D. Cumming, Does Anovulation Exist in Eumenorrheic Women?, Obstetrics and Gynecology, vol.102, issue.2, pp.317-335, 2003.

L. Manenschijn, G. Rulanda, F. P-m-van-kruysbergen, J. W. Jong, E. Koper et al., Shift Work at Young Age Is Associated with Elevated Long-Term Cortisol Levels and Body Mass Index, The Journal of Clinical Endocrinology and Metabolism, vol.96, issue.11, pp.1862-1867, 2011.

. Marcheva, K. M. Biliana, E. D. Ramsey, Y. Buhr, H. Kobayashi et al., Disruption of the Clock Components CLOCK and BMAL1 Leads to Hypoinsulinaemia and Diabetes, Nature, vol.466, issue.7306, pp.627-658, 2010.

,

J. L. Marino, L. Victoria, C. Holt, S. Chen, and . Davis, Shift Work, HCLOCK T3111C Polymorphism, and Endometriosis Risk, Epidemiology, vol.19, issue.3, pp.477-84, 2008.

H. Matsui, Y. Takatsu, S. Kumano, H. Matsumoto, and T. Ohtaki, Peripheral Administration of Metastin Induces Marked Gonadotropin Release and Ovulation in the Rat, Biochemical and Biophysical Research Communications, vol.320, issue.2, pp.383-88, 2004.

S. Matsumoto, S. Tamada, and . Konuma, Endocrinological Analysis of Environmental Menstrual Disorders, International Journal of Fertility, vol.24, issue.4, pp.233-272, 1979.

C. Mayer and U. Boehm, Female Reproductive Maturation in the Absence of Kisspeptin/GPR54 Signaling, Nature Neuroscience, vol.14, issue.6, pp.704-714, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00634803

,

T. Mcelhinny, C. Sisk, K. Holekamp, and L. Smale, A Morning Surge in Plasma Luteinizing Hormone Coincides with Elevated Fos Expression in Gonadotropin-Releasing Hormone-Immunoreactive Neurons in the Diurnal Rodent, Arvicanthis Niloticus, Biology of Reproduction, vol.61, issue.4, pp.1115-1137, 1999.

A. C. Mclean, N. Valenzuela, S. Fai, and S. Bennett, Performing Vaginal Lavage, Crystal Violet Staining, and Vaginal Cytological Evaluation for Mouse Estrous Cycle Staging Identification, Journal of Visualized Experiments : JoVE, issue.67, p.4389, 2012.

E. J. Mead, J. J. Maguire, R. E. Kuc, and A. Davenport, Kisspeptins Are Novel Potent Vasoconstrictors in Humans, with a Discrete Localization of Their Receptor, G Protein-Coupled Receptor 54, to Atherosclerosis-Prone Vessels, Endocrinology, vol.148, issue.1, pp.140-187, 2007.

S. Melmed and K. U. , The Pituitary, 2010.

M. Menaker, Z. C. Murphy, and M. T. Sellix, Central Control of Peripheral Circadian Oscillators, Current Opinion in Neurobiology, vol.23, issue.5, pp.741-787, 2013.

,

A. L. Mereness, C. Zachary, A. C. Murphy, S. Forrestel, C. Butler et al., , 2016.

, Ovarian Theca Cells Disrupts Ovulation in Female Mice, Endocrinology, vol.157, issue.2, pp.913-940

S. Messager, E. E. Chatzidaki, D. Ma, A. G. Hendrick, D. Zahn et al., Kisspeptin Directly Stimulates Gonadotropin-Releasing Hormone Release via G Protein-Coupled Receptor 54, Proceedings of the National Academy of Sciences, vol.102, issue.5, pp.1761-66, 2005.
URL : https://hal.archives-ouvertes.fr/hal-02676989

K. Messing, M. Saurel-cubizolles, M. Bourgine, and M. Kaminski, Menstrual-Cycle Characteristics and Work Conditions of Workers in Poultry Slaughterhouses and Canneries, Scandinavian Journal of Work, vol.18, issue.5, pp.302-311, 1992.

, Factors Associated with Dysmenorrhea among Workers in French Poultry Slaughterhouses and Canneries, Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association, vol.35, issue.5, pp.493-500, 1993.

B. H. Miller, S. L. Olson, J. E. Levine, F. W. Turek, T. H. Horton et al., Vasopressin Regulation of the Proestrous Luteinizing Hormone Surge in Wild-Type and Clock Mutant Mice, Biology of Reproduction, vol.75, issue.5, pp.778-84, 2006.

B. H. Miller, S. L. Olson, F. W. Turek, J. E. Levine, T. H. Horton et al., Circadian Clock Mutation Disrupts Estrous Cyclicity and Maintenance of Pregnancy, Current Biology : CB, vol.14, issue.15, pp.1367-73, 2004.

,

. Miller, H. Brooke, and J. Takahashi, Central Circadian Control of Female Reproductive Function, Frontiers in Endocrinology, vol.4, p.195, 2013.

M. A. Mittelman-smith, H. Williams, S. J. Krajewski-hall, N. T. Mcmullen, and N. E. Rance, Role for Kisspeptin/Neurokinin B/Dynorphin (KNDy) Neurons in Cutaneous Vasodilatation and the Estrogen Modulation of Body Temperature, Proceedings of the National Academy of Sciences, vol.109, issue.48, pp.19846-51, 2012.

,

F. Miyauchi, K. Nanjo, and . Otsuka, Effects of Night Shift on Plasma Concentrations of Melatonin, LH, FSH and Prolactin, and Menstrual Irregularity, 1992.

, Japanese Journal of Industrial Health, vol.34, issue.6, pp.545-50

M. Moalla, F. Hadj-kacem, A. F. Al-mutery, and M. Mahfood, Nonstop Mutation in the Kisspeptin 1 Receptor (KISS1R) Gene Causes Normosmic Congenital Hypogonadotropic Hypogonadism, Journal of Assisted Reproduction and Genetics, 2019.

S. M. Moenter, . Caraty, F. Locatelli, and . Karsch, Pattern of Gonadotropin-Releasing Hormone (GnRH) Secretion Leading up to Ovulation in the Ewe: Existence of a Preovulatory GnRH Surge, Endocrinology, vol.129, issue.3, pp.1175-82, 1991.
URL : https://hal.archives-ouvertes.fr/hal-02715123

,

M. L. Moline and H. Albers, Response of Circadian Locomotor Activity and the Proestrous Luteinizing Hormone Surge to Phase Shifts of the Light-Dark Cycle in the Hamster, Physiology & Behavior, vol.43, issue.4, pp.435-475, 1988.

M. Moline, H. Albers, R. Todd, and M. , Light-Dark Entrainment of Proestrous LH Surges and Circadian Locomotor Activity in Female Hamsters, Hormones and Behavior, vol.15, issue.4, pp.451-58, 1981.

I. Molnár, . Kalló, E. Liposits, and . Hrabovszky, Estradiol Down-Regulates RF-Amide-Related Peptide (RFRP) Expression in the Mouse Hypothalamus, Endocrinology, vol.152, issue.4, pp.1684-90, 2011.

H. Morello, . Caligaris, S. Haymal, and . Taleisnik, Daily Variations in the Sensitivity of Proestrous LH Surge in the Inhibitory Effect of Intraventricular Injection of 5-HT or GABA in Rats, Canadian Journal of Physiology and Pharmacology, vol.70, issue.4, pp.447-51, 1992.

K. Mounzih, R. Lu, and F. F. Chehab, Leptin Treatment Rescues the Sterility of Genetically Obese Ob/Ob Males, Endocrinology, vol.138, issue.3, pp.1190-93, 1997.

,

E. Mozurkewich, M. Luke, F. Avni, and . Wolf, Working Conditions and Adverse Pregnancy Outcome: A Meta-Analysis, Obstetrics and Gynecology, vol.95, issue.4, pp.623-658, 2000.

A. I. Muir, N. Chamberlain, D. Elshourbagy, D. Michalovich, . Moore et al., AXOR12, a Novel Human G Protein-Coupled Receptor, Activated by the Peptide KiSS-1, The Journal of Biological Chemistry, vol.276, issue.31, pp.28969-75, 2001.

,

K. Nakamura, . Shinohara, F. Funabashi, and . Kimura, Effect of Estrogen on the Expression of Cry1 and Cry2 MRNAs in the Suprachiasmatic Nucleus of Female Rats, Neuroscience Research, vol.41, issue.3, pp.251-55, 2001.

T. J. Nakamura, T. Michael, M. Sellix, G. D. Menaker, and . Block, Estrogen Directly Modulates Circadian Rhythms of PER2 Expression in the Uterus, American Journal of Physiology. Endocrinology and Metabolism, vol.295, issue.5, pp.1025-1056, 2008.

,

O. Nalbantoglu, G. Arslan, O. Koprulu, F. Hazan, S. Gursoy et al., Three Siblings with Idiopathic Hypogonadotropic Hypogonadism in a Nonconsanguineous Family: A Novel KISS1R/GPR54 Loss-of-Function Mutation, Journal of Clinical Research in Pediatric Endocrinology, vol.0, issue.0, pp.0-0, 2019.

,

V. M. Navarro, J. M. Castellano, R. Fernández-fernández, S. Tovar, J. Roa et al., Characterization of the Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, the Natural Ligand of GPR54, Endocrinology, vol.146, issue.1, pp.156-63, 2005.

V. Navarro, J. Castellano, M. Fernández-fernández, J. Barreiro, J. Roa et al., Developmental and Hormonally Regulated Messenger Ribonucleic Acid Expression of KiSS-1 and Its Putative Receptor, GPR54, in Rat Hypothalamus and Potent Luteinizing Hormone-Releasing Activity of KiSS-1 Peptide, Endocrinology, vol.145, issue.10, pp.4565-74, 2004.

,

V. Navarro, J. Fernández-fernández, J. Castellano, . Roa, M. Mayen et al., Advanced Vaginal Opening and Precocious Activation of the Reproductive Axis by KiSS-1 Peptide, the Endogenous Ligand of GPR54, The Journal of Physiology, vol.561, issue.2, pp.379-86, 2004.

G. Neal-perry, D. Lebesgue, M. Lederman, and J. Shu,

. Anne-m-etgen, The Excitatory Peptide Kisspeptin Restores the Luteinizing Hormone Surge and Modulates Amino Acid Neurotransmission in the Medial Preoptic Area of Middle-Aged Rats, Endocrinology, vol.150, issue.8, pp.3699-3708, 2009.

,

J. Nelson, L. Felicio, P. Randall, C. Sims, and C. Finch, A Longitudinal Study of Estrous Cyclicity in Aging C57BL/6J Mice: I. Cycle Frequency, Length and Vaginal Cytology, Biology of Reproduction, vol.27, issue.2, pp.327-366, 1982.

,

S. D. Noel, L. Kim, D. I. Keen, E. J. Baumann, E. Filardo et al., Involvement of G Protein-Coupled Receptor 30 (GPR30) in Rapid Action of Estrogen in Primate LHRH Neurons, Molecular Endocrinology, vol.23, issue.3, pp.349-59, 2009.

,

T. Nurminen, Shift Work and Reproductive Health, Scandinavian Journal of Work, vol.24, pp.28-34, 1998.

S. Ogawa, J. Chan, J. Gustafsson, S. Kenneth, D. W. Korach et al., Estrogen Increases Locomotor Activity in Mice through Estrogen Receptor Alpha: Specificity for the Type of Activity, Endocrinology, vol.144, issue.1, pp.230-269, 2003.

,

H. Oishi, C. Klausen, G. E. Bentley, T. Osugi, K. Tsutsui et al., The Human Gonadotropin-Inhibitory Hormone Ortholog RFamide-Related Peptide-3 Suppresses Gonadotropin-Induced Progesterone Production in Human Granulosa Cells, Endocrinology, vol.153, issue.7, pp.3435-3480, 2012.

J. Olsen, Cigarette Smoking, Tea and Coffee Drinking, and Subfecundity, American Journal of Epidemiology, vol.133, issue.7, pp.734-773, 1991.

L. W. Opperhuizen, K. I. Van-kerkhof, W. Proper, A. Rodenburg, and . Kalsbeek, Rodent Models to Study the Metabolic Effects of Shiftwork in Humans, Frontiers in Pharmacology, vol.6, p.50, 2015.

. Oster, Adrenal Glucocorticoids Have a Key Role in Circadian Resynchronization in a Mouse Model of Jet Lag. -PubMed -NCBI, J Clin Invest, 2010.

E. N. Ottem, J. G. Godwin, and S. L. Petersen, Glutamatergic Signaling through the N-Methyl-D-Aspartate Receptor Directly Activates Medial Subpopulations of Luteinizing Hormone-Releasing Hormone (LHRH) Neurons, but Does Not Appear to Mediate the Effects of Estradiol on LHRH Gene Expression, Endocrinology, vol.143, issue.12, pp.4837-4882, 2002.

I. Oyama, T. Kubo, Y. Fujino, K. Kadowaki, M. Kunimoto et al., Retrospective Cohort Study of the Risk of Impaired Glucose Tolerance among Shift Workers, Scandinavian Journal of Work, vol.38, issue.4, pp.337-379, 2012.

E. Palm, . Van-der, V. Beek, R. Wiegant, A. Buijs et al., Vasopressin Induces a Luteinizing Hormone Surge in Ovariectomized, Estradiol-Treated Rats with Lesions of the Suprachiasmatic Nucleus, Neuroscience, vol.93, issue.2, pp.659-66, 1999.

E. M. Palm, . Van-der, . Beek, M. Victor, . Wiegant et al., The Stimulatory Effect of Vasopressin on the Luteinizing Hormone Surge in Ovariectomized, Estradiol-Treated Rats Is Time-Dependent, Brain Research, vol.901, issue.1-2, pp.109-125, 2001.

A. Pan, S. Eva, Q. Schernhammer, F. B. Sun, and . Hu, Rotating Night Shift Work and Risk of Type 2 Diabetes: Two Prospective Cohort Studies in Women, PLoS Medicine, vol.8, issue.12, p.1001141, 2011.

K. Papantoniou, O. J. Pozo, A. Espinosa, J. Marcos, G. Castaño-vinyals et al., Increased and Mistimed Sex Hormone Production in Night Shift Workers, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, vol.24, pp.854-63, 2015.

S. Park, J. Nam, J. Lee, S. Oh, H. Kang et al., Association between Night Work and Cardiovascular Diseases: Analysis of the 3rd, 2015.

, Korean Working Conditions Survey, Annals of Occupational and Environmental Medicine, vol.27, issue.1, p.15

T. Parkening, T. Collins, and E. Smith, Plasma and Pituitary Concentrations of LH, FSH, and Prolactin in Aging C57BL/6 Mice at Various Times of the Estrous Cycle, Neurobiology of Aging, vol.3, issue.1, pp.90058-90064, 1982.

C. Pati and R. , Shift Work: Consequences and Management, Curr Sci, vol.81, pp.32-52, 2001.

C. Pauerstein, C. Eddy, H. Croxatto, R. Hess, T. Siler-khodr et al., Temporal Relationships of Estrogen, Progesterone, and Luteinizing Hormone Levels to Ovulation in Women and Infrahuman Primates, American Journal of Obstetrics and Gynecology, vol.130, issue.8, pp.876-86, 1978.

B. Pesch, V. Harth, S. Rabstein, C. Baisch, M. Schiffermann et al., Night Work and Breast Cancer -Results from the, 2010.

G. German and . Study, Scandinavian Journal of Work, vol.36, issue.2, pp.134-175

S. L. Petersen, E. N. Ottem, and C. Carpenter, Direct and Indirect Regulation of Gonadotropin-Releasing Hormone Neurons by Estradiol, Biology of Reproduction, vol.69, issue.6, pp.1771-78, 2003.

R. Piet, H. Dunckley, K. Lee, and A. E. Herbison, Vasoactive Intestinal Peptide Excites GnRH Neurons in Male and Female Mice, Endocrinology, vol.157, issue.9, pp.3621-3651, 2016.

R. Piet, A. Fraissenon, U. Boehm, and A. E. Herbison, Estrogen Permits Vasopressin Signaling in Preoptic Kisspeptin Neurons in the Female Mouse, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.35, issue.17, pp.6881-92, 2015.

V. Pilorz and S. Steinlechner, Low Reproductive Success in Per1 and Per2 Mutant Mouse Females Due to Accelerated Ageing?, Reproduction, vol.135, issue.4, pp.559-68, 2008.

L. Pinilla, E. Aguilar, C. Dieguez, P. Robert, M. Millar et al., Kisspeptins and Reproduction: Physiological Roles and Regulatory Mechanisms, Physiological Reviews, vol.92, issue.3, pp.1235-1316, 2012.

T. M. Plant, The Neurobiological Mechanism Underlying Hypothalamic GnRH Pulse Generation: The Role of Kisspeptin Neurons in the Arcuate Nucleus, F1000Research, vol.8, p.982, 2019.

T. M. Plant, The Role of KiSS-1 in the Regulation of Puberty in Higher Primates, European Journal of Endocrinology / European Federation of Endocrine Societies, vol.155, 2006.

, , pp.11-17

T. M. Plant, S. Ramaswamy, and M. Dipietro, Repetitive Activation of Hypothalamic G Protein-Coupled Receptor 54 with Intravenous Pulses of Kisspeptin in the Juvenile Monkey (Macaca Mulatta) Elicits a Sustained Train of Gonadotropin-Releasing Hormone Discharges, Endocrinology, vol.147, issue.2, pp.1007-1020, 2006.

,

M. Poling, J. Quennell, G. Anderson, and A. Kauffman, Kisspeptin Neurones Do Not Directly Signal to RFRP-3 Neurones but RFRP-3 May Directly Modulate a Subset of Hypothalamic Kisspeptin Cells in Mice, Journal of Neuroendocrinology, vol.25, issue.10, pp.876-86, 2013.

J. Quennell, M. Z-rizwan, H. Relf, and G. Anderson, Developmental and Steroidogenic Effects on the Gene Expression of RFamide Related Peptides and Their Receptor in the Rat Brain and Pituitary Gland, Journal of Neuroendocrinology, vol.22, issue.4, pp.309-325, 2010.

S. Rabstein, V. Harth, B. Pesch, D. Pallapies, A. Lotz et al., Night Work and Breast Cancer Estrogen Receptor Status--Results from the German GENICA Study, Scandinavian Journal of Work, vol.39, issue.5, pp.448-55, 2013.

S. Radovick, J. E. Levine, and A. Wolfe, Estrogenic Regulation of the GnRH Neuron, Frontiers in Endocrinology, vol.3, p.52, 2012.

,

M. Ralph, R. Foster, F. Davis, and M. Menaker, Transplanted Suprachiasmatic Nucleus Determines Circadian Period, Science, vol.247, issue.4945, pp.975-78, 1990.

O. Reeth and . Van, Sleep and Circadian Disturbances in Shift Work: Strategies for Their Management, Hormone Research, vol.49, issue.3-4, pp.158-62, 1998.

F. G. Revel, M. Saboureau, M. Masson-pévet, P. Pévet, J. D. Mikkelsen et al., Kisspeptin Mediates the Photoperiodic Control of Reproduction in Hamsters, Current Biology : CB, vol.16, issue.17, pp.1730-1765, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00093418

,

S. Ribeiro, L. Hampton, . Morgan, J. Deacon, and . Arendt, Altered Postprandial Hormone and Metabolic Responses in a Simulated Shift Work Environment, The Journal of Endocrinology, vol.158, issue.3, pp.305-315, 1998.

C. Ribeiro, . M-leite, C. Kalil, J. R-franci, R. Anselmo-franci et al., Kisspeptin Regulates Tuberoinfundibular Dopaminergic Neurones and Prolactin Secretion in an Oestradiol-Dependent Manner in Male and Female Rats, Journal of Neuroendocrinology, vol.27, issue.2, pp.88-99, 2015.

N. Richard, . Galmiche, . Corvaisier, M. Caraty, and . Kottler, KiSS-1 and GPR54, 2008.

, Genes Are Co-Expressed in Rat Gonadotrophs and Differentially Regulated in Vivo by Oestradiol and Gonadotrophin-Releasing Hormone, Journal of Neuroendocrinology, vol.20, issue.3, pp.381-93

J. Roa, J. Castellano, V. Navarro, D. Handelsman, L. Pinilla et al., Kisspeptins and the Control of Gonadotropin Secretion in Male and Female Rodents, Peptides, vol.30, issue.1, pp.57-66, 2009.

J. L. Robertson, K. Donald, H. O. Clifton, and . De-la-iglesia,

. Alexander-s-kauffman, Circadian Regulation of Kiss1 Neurons: Implications for Timing the Preovulatory Gonadotropin-Releasing Hormone/Luteinizing Hormone Surge, Endocrinology, vol.150, issue.8, pp.3664-71, 2009.

A. M. Rometo, J. Sally, M. L. Krajewski, N. E. Voytko, and . Rance, Hypertrophy and Increased Kisspeptin Gene Expression in the Hypothalamic Infundibular Nucleus of Postmenopausal Women and Ovariectomized Monkeys, The Journal of Clinical Endocrinology and Metabolism, vol.92, issue.7, pp.2744-50, 2007.

,

O. K. Rønnekleiv, C. Zhang, M. A. Bosch, and M. Kelly, Kisspeptin and Gonadotropin-Releasing Hormone Neuronal Excitability: Molecular Mechanisms Driven by 17?-Estradiol, Neuroendocrinology, 2014.

J. Roos, S. Johnson, S. Weddell, E. Godehardt, J. Schiffner et al., Monitoring the Menstrual Cycle: Comparison of Urinary and Serum Reproductive Hormones Referenced to True Ovulation, The European Journal of Contraception & Reproductive Health Care : The Official Journal of the European Society of Contraception, vol.20, issue.6, pp.438-50, 2015.

,

R. Rosa, M. Bonnet, R. R-bootzin, C. Eastman, T. Monk et al., Intervention Factors for Promoting Adjustment to Nightwork and Shiftwork, Occupational Medicine, vol.5, issue.2, pp.391-415, 1990.

D. Rosenfeld, R. Chudow, and . Bronson, Diagnosis of Luteal Phase Inadequacy, Obstetrics and Gynecology, vol.56, issue.2, pp.193-96, 1980.

A. K. Roseweir, A. S. Kauffman, J. T. Smith, K. A. Guerriero, K. Morgan et al., Discovery of Potent Kisspeptin Antagonists Delineate Physiological Mechanisms of Gonadotropin Regulation, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.29, issue.12, pp.3920-3949, 2009.

R. Rosmond, P. Lapidus, and . Björntorp, The Influence of Occupational and Social Factors on Obesity and Body Fat Distribution in Middle-Aged Men, International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, vol.20, issue.7, pp.599-607, 1996.

N. Roux, J. De, J. Carel, and . Leger, Congenital Hypogonadotropic Hypogonadism: A Trait Shared by Several Complex Neurodevelopmental Disorders, Endocrine Development, vol.29, pp.72-86, 2016.

N. Roux, E. De, J. Genin, F. Carel, J. Matsuda et al., Hypogonadotropic Hypogonadism Due to Loss of Function of the KiSS1-Derived Peptide Receptor GPR54, Proceedings of the National Academy of Sciences of the United States of America, vol.100, pp.10972-76, 2003.

,

S. E. Royston, A. Yasui, S. Kondilis, J. Lord, M. A-katzenellenbogen et al., ESR1 and ESR2 Differentially Regulate Daily and Circadian Activity Rhythms in Female Mice, Endocrinology, vol.155, issue.7, pp.2613-2636, 2014.

K. A. Russo, J. L. La, B. Shannon, . Stephens, C. Matthew et al., Circadian Control of the Female Reproductive Axis Through Gated Responsiveness of the RFRP-3 System to VIP Signaling, Endocrinology, 2015.

N. Santoro, W. Filicori, and . Crowley, Hypogonadotropic Disorders in Men and Women: Diagnosis and Therapy with Pulsatile Gonadotropin-Releasing Hormone, Endocrine Reviews, vol.7, issue.1, pp.11-23, 1986.

R. S. Sasaki, M. S. Approbato, C. Mônica, E. Maia, C. R. Aparecida-de-b-fleury et al., Patients' Auto Report of Regularity of Their Menstrual Cycles. Medical History Is Very Reliable to Predict Ovulation. A Cross-Sectional Study, JBRA Assisted Reproduction, vol.20, issue.3, pp.118-140, 2016.

,

C. H. Schernhammer, F. Kroenke, S. E. Laden, and . Hankinson, Night Work and Risk of Breast Cancer, Epidemiology, vol.17, issue.1, pp.108-119, 2006.

F. Schernhammer, . Laden, W. Speizer, D. Willett, . Hunter et al., Rotating Night Shifts and Risk of Breast Cancer in Women Participating in the Nurses' Health Study, Journal of the National Cancer Institute, vol.93, issue.20, pp.1563-68, 2001.

A. J. Scott, Shift Work and Health, Primary Care, vol.27, issue.4, pp.1057-79, 2000.

K. M. Scully, A. S-gleiberman, J. Lindzey, D. B-lubahn, K. Korach et al., Role of Estrogen Receptor-Alpha in the Anterior Pituitary Gland, Molecular Endocrinology, vol.11, issue.6, pp.674-81, 1997.

M. Sébert, D. Lomet, P. Ben-saïd, C. Monget, R. Briant et al., Insights into the Mechanism by Which Kisspeptin Stimulates a Preovulatory LH Surge and Ovulation in Seasonally Acyclic Ewes: Potential Role of Estradiol, Domestic Animal Endocrinology, vol.38, issue.4, pp.289-98, 2010.

M. T. Sellix and M. Menaker, Circadian Clocks in the Ovary, Trends in Endocrinology and Metabolism: TEM, vol.21, issue.10, pp.628-664, 2010.

,

S. B. Seminara, S. Messager, E. E. Chatzidaki, R. R. Thresher, J. S. Acierno et al., The GPR54 Gene as a Regulator of Puberty, New England Journal of Medicine, vol.349, issue.17, pp.1614-1641, 2003.

,

R. Semple, J. C-achermann, J. Ellery, F. I-s-farooqi, R. Karet et al., Two Novel Missense Mutations in g Protein-Coupled Receptor 54 in a Patient with Hypogonadotropic Hypogonadism, The Journal of Clinical Endocrinology and Metabolism, vol.90, issue.3, pp.1849-55, 2005.

M. Shahab, C. Mastronardi, S. B. Seminara, F. William, S. R. Crowley et al., Increased Hypothalamic GPR54 Signaling: A Potential Mechanism for Initiation of Puberty in Primates, Proceedings of the National Academy of Sciences of the United States of America, vol.102, issue.6, pp.2129-2163, 2005.

,

N. Shaw, S. Histed, S. Srouji, H. Yang, J. Lee et al., Estrogen Negative Feedback on Gonadotropin Secretion: Evidence for a Direct Pituitary Effect in Women, The Journal of Clinical Endocrinology and Metabolism, vol.95, issue.4, pp.1955-61, 2010.

,

J. Shi, B. Zhang, J. Choi, Y. Gao, H. Li et al., Age at Menarche and Age at Natural Menopause in East Asian Women: A Genome-Wide Association Study, AGE, vol.38, issue.5-6, pp.513-536, 2016.

,

T. Shimizu, Y. Hirai, C. Murayama, A. Miyamoto, H. Miyazaki et al., Circadian Clock Genes Per2 and Clock Regulate Steroid Production, Cell Proliferation, and Luteinizing Hormone Receptor Transcription in Ovarian Granulosa Cells, Biochemical and Biophysical Research Communications, vol.412, issue.1, pp.132-167, 2011.

K. Shinohara, Y. Tominaga, S. Isobe, and . Inouye, Photic Regulation of Peptides Located in the Ventrolateral Subdivision of the Suprachiasmatic Nucleus of the Rat: Daily Variations of Vasoactive Intestinal Polypeptide, Gastrin-Releasing Peptide, and Neuropeptide Y, The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, vol.13, issue.2, pp.793-800, 1993.

L. Shortridge, G. Lemasters, B. Valanis, and V. Hertzberg, Menstrual Cycles in Nurses Handling Antineoplastic Drugs, Cancer Nursing, vol.18, issue.6, pp.439-483, 1995.

L. G. Silveira, S. D. Noel, A. P. Silveira-neto, A. P. Abreu, V. N. Brito et al., Mutations of the KISS1 Gene in Disorders of Puberty, The Journal of Clinical Endocrinology & Metabolism, vol.95, issue.5, pp.2276-80, 2010.

,

C. Simon, G. Weibel, and . Brandenberger, Twenty-Four-Hour Rhythms of Plasma Glucose and Insulin Secretion Rate in Regular Night Workers, American Journal of Physiology. Endocrinology and Metabolism, vol.278, issue.3, pp.413-433, 2000.

. Simonneaux, A Kiss to Drive Rhythms in Reproduction, European Journal of Neuroscience, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02390080

I. Simonneaux, C. Bur, L. Ancel, P. Ansel, and . Klosen, A Kiss for Daily and Seasonal Reproduction, Progress in Brain Research, vol.199, pp.423-460, 2012.

,

V. Simonneaux and T. Bahougne, A Multi-Oscillatory Circadian System Times Female Reproduction, Frontiers in Endocrinology, vol.6, 2015.

,

S. P. Singh, A. Wolfe, Y. Ng, A. Sara, C. Divall et al., Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-Specific Deletion of Estrogen Receptor Alpha (ESR1), Biology of Reproduction, vol.81, issue.3, pp.488-96, 2009.

,

C. M. Small, K. Amita, M. Manatunga, . Klein, C. E. Heather-s-feigelson et al., Menstrual Cycle Characteristics: Associations with Fertility and Spontaneous Abortion, Epidemiology, vol.17, issue.1, pp.52-60, 2006.

B. Smarr, J. Gile, and H. Iglesia, Oestrogen-Independent Circadian Clock Gene Expression in the Anteroventral Periventricular Nucleus in Female Rats: Possible Role as an Integrator for Circadian and Ovarian Signals Timing the Luteinising Hormone Surge, Journal of Neuroendocrinology, vol.25, issue.12, pp.1273-79, 2013.

,

K. Smith-dijulio, N. Sullivan-mitchell, and . Woods, Concordance of Retrospective and Prospective Reporting of Menstrual Irregularity by Women in the Menopausal Transition, Climacteric : The Journal of the International Menopause Society, vol.8, issue.4, pp.390-97, 2005.

B. Smith, D. Acohido, R. Clifton, and . Steiner, KiSS-1 Neurones Are Direct Targets for Leptin in the Ob/Ob Mouse, Journal of Neuroendocrinology, vol.18, issue.4, pp.298-303, 2006.

,

J. T. Smith, J. Matthew, E. F. Cunningham, . Rissman, K. Donald et al., Regulation of Kiss1 Gene Expression in the Brain of the Female Mouse, Endocrinology, vol.146, issue.9, pp.3686-92, 2005.

. Smith, P. Jiennes, and . Wise, Localization of the VIP2 Receptor Protein on GnRH Neurons in the Female Rat, Endocrinology, vol.141, issue.11, pp.4317-4337, 2000.

,

M. Smith, A. Shahab, K. Pereira, I. J. Pau, and . Clarke, Hypothalamic Expression of KISS1 and Gonadotropin Inhibitory Hormone Genes During the Menstrual Cycle of a Non-Human Primate1, Biology of Reproduction, vol.83, issue.4, pp.568-77, 2010.

C. Sonigo, J. Bouilly, N. Carré, V. Tolle, A. Caraty et al., Hyperprolactinemia-Induced Ovarian Acyclicity Is Reversed by Kisspeptin Administration, The Journal of Clinical Investigation, vol.122, issue.10, pp.3791-95, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01129684

,

. Spieler, Temporal Relationships between Ovulation and Defined Changes in the Concentration of Plasma Estradiol-17 Beta, Luteinizing Hormone, Follicle-Stimulating Hormone, and Progesterone. I. Probit Analysis. World Health Organization, Task Force on Methods for Th, American Journal of Obstetrics and Gynecology, vol.138, issue.4, pp.383-90, 1980.

, , pp.90133-90140

A. Spinelli, J. Figà-talamanca, and . Osborn, Time to Pregnancy and Occupation in a Group of Italian Women, International Journal of Epidemiology, vol.26, issue.3, pp.601-610, 1997.

F. Steyn, Y. Wan, J. Clarkson, A. Veldhuis, C. E-herbison et al., Development of a Methodology for and Assessment of Pulsatile Luteinizing Hormone Secretion in Juvenile and Adult Male Mice, Endocrinology, vol.154, issue.12, pp.4939-4984, 2013.

,

L. J. Stocker, S. Nicholas, Y. C. Macklon, S. J. Cheong, and . Bewley, Influence of Shift Work on Early Reproductive Outcomes: A Systematic Review and Meta-Analysis, Obstetrics and Gynecology, vol.124, issue.1, pp.99-110, 2014.

,

K. C. Summa, M. H. Vitaterna, and F. W. Turek, Environmental Perturbation of the Circadian Clock Disrupts Pregnancy in the Mouse, PloS One, vol.7, issue.5, p.37668, 2012.

G. Sundell, B. Milsom, and . Andersch, Factors Influencing the Prevalence and Severity of Dysmenorrhoea in Young Women, British Journal of Obstetrics and Gynaecology, vol.97, issue.7, pp.588-94, 1990.

R. E. Szawka, A. B. Ribeiro, M. Cristiane, . Leite, V. Cleyde et al., Kisspeptin Regulates Prolactin Release through Hypothalamic Dopaminergic Neurons, Endocrinology, vol.151, issue.7, pp.3247-57, 2010.

N. N. Takasu, J. Takahiro, . Nakamura, T. Isao, T. Tokuda et al., Recovery from Age-Related Infertility under Environmental Light-Dark Cycles Adjusted to the Intrinsic Circadian Period, Cell Reports, vol.12, issue.9, pp.1407-1420, 2015.

K. Takumi, N. Iijima, S. Higo, and H. Ozawa, Immunohistochemical Analysis of the Colocalization of Corticotropin-Releasing Hormone Receptor and Glucocorticoid Receptor in Kisspeptin Neurons in the Hypothalamus of Female Rats, Neuroscience Letters, vol.531, issue.1, pp.40-45, 2012.

. Tang, R. Zi-run, Z. Zhang, S. Lian, K. Deng et al., Estrogen-Receptor Expression and Function in Female Reproductive Disease, Cells, vol.8, issue.10, p.1123, 2019.

M. Taziaux, S. Annemieke, . Staphorsius, A. Mohammad, . Ghatei et al., Kisspeptin Expression in the Human Infundibular Nucleus in Relation to Sex, Gender Identity, and Sexual Orientation, The Journal of Clinical Endocrinology and Metabolism, vol.101, issue.6, pp.2380-89, 2016.

,

S. D. Teles, . Bianco, . Vinicius-nahime, E. B. Brito, W. Trarbach et al., A GPR54-Activating Mutation in a Patient with Central Precocious Puberty, The New England Journal of Medicine, vol.358, issue.7, pp.709-724, 2008.

,

E. Teles, S. Trarbach, . Noel, . Guerra-junior, . Jorge et al., A Novel Homozygous Splice Acceptor Site Mutation of KISS1R in Two Siblings with Normosmic Isolated Hypogonadotropic Hypogonadism, European Journal of Endocrinology / European Federation of Endocrine Societies, vol.163, issue.1, pp.29-34, 2010.

,

. Tenenbaum-rakover, M. Yardena, A. Commenges-ducos, C. Iovane, and . Aumas, Neuroendocrine Phenotype Analysis in Five Patients with Isolated Hypogonadotropic Hypogonadism Due to a L102P Inactivating Mutation of GPR54, The Journal of Clinical Endocrinology and Metabolism, vol.92, issue.3, pp.1137-1181, 2007.

H. Themmen, Mutations of Gonadotropins and Gonadotropin Receptors: Elucidating the Physiology and Pathophysiology of Pituitary-Gonadal Function, Endocrine Reviews, vol.21, issue.5, pp.551-83, 2000.

T. Theorell, M. Ahlberg-hulten, . Jodko, B. Sigala, and . De-la-torre, Influence of Job Strain and Emotion on Blood Pressure in Female Hospital Personnel during Workhours, Scandinavian Journal of Work, vol.19, issue.5, pp.313-331, 1993.

E. Thompson, M. Patterson, K. Murphy, K. Smith, J. Dhillo et al., Central and Peripheral Administration of Kisspeptin-10 Stimulates the Hypothalamic-Pituitary-Gonadal Axis, Journal of Neuroendocrinology, vol.16, issue.10, pp.850-58, 2004.

,

J. Tomikawa, T. Homma, S. Tajima, T. Shibata, Y. Inamoto et al., Molecular Characterization and Estrogen Regulation of Hypothalamic KISS1 Gene in the Pig, Biology of Reproduction, vol.82, issue.2, pp.313-332, 2010.

,

K. Tonsfeldt, C. Goodall, K. Latham, and P. Chappell, Oestrogen Induces Rhythmic Expression of the Kisspeptin-1 Receptor GPR54 in Hypothalamic Gonadotrophin-Releasing Hormone-Secreting GT1-7 Cells, Journal of Neuroendocrinology, vol.23, issue.9, pp.823-853, 2011.

A. Topaloglu, J. A. Kemal, L. Tello, M. N. Damla-kotan, M. Ozbek et al., Inactivating KISS1 Mutation and Hypogonadotropic Hypogonadism, New England Journal of Medicine, vol.366, issue.7, pp.629-664, 2012.

A. Topaloglu, F. Kemal, M. Reimann, A. Guclu, . Serap-yalin et al., TAC3 and TACR3 Mutations in Familial Hypogonadotropic Hypogonadism Reveal a Key Role for Neurokinin B in the Central Control of Reproduction, Nature Genetics, vol.41, issue.3, pp.354-58, 2009.

,

A. Topaloglu, J. A. Kemal, . Tello, . Damla-kotan, N. Mehmet et al., Inactivating KISS1 Mutation and Hypogonadotropic Hypogonadism, The New England Journal of Medicine, vol.366, issue.7, pp.629-664, 2012.

S. Tovar, M. Vázquez, V. Navarro, J. Fernández-fernández, E. Castellano et al., Effects of Single or Repeated Intravenous Administration of Kisspeptin upon Dynamic LH Secretion in Conscious Male Rats, Endocrinology, vol.147, issue.6, pp.2696-2704, 2006.

,

P. Tuntiseranee, . Olsen, and . Geater, Are Long Working Hours and Shiftwork Risk Factors for Subfecundity? A Study among Couples from Southern Thailand, Occupational and Environmental Medicine, vol.55, issue.2, pp.99-105, 1998.

T. Ubuka, K. Inoue, Y. Fukuda, T. Mizuno, K. Ukena et al., Identification, Expression, and Physiological Functions of Siberian Hamster Gonadotropin-Inhibitory Hormone, Endocrinology, vol.153, issue.1, pp.373-85, 2012.

T. Ubuka, K. Morgan, A. J. Pawson, T. Osugi, and S. Vishwajit,

H. Chowdhury, K. Minakata, R. P. Tsutsui, and G. E. Millar,

. Bentley, Identification of Human GnIH Homologs, RFRP-1 and RFRP-3, and the Cognate Receptor, GPR147 in the Human Hypothalamic Pituitary Axis, PLoS ONE, vol.4, issue.12, p.8400, 2009.

M. Uchikawa, M. Kawamura, N. Yamauchi, and M. Hattori, Down-Regulation of Circadian Clock Gene Period 2 in Uterine Endometrial Stromal Cells of Pregnant Rats during Decidualization, Chronobiology International, vol.28, issue.1, pp.1-9, 2011.

,

M. Ulhôa, L. E-c-marqueze, C. Burgos, and . Moreno, Shift Work and Endocrine Disorders, International Journal of Endocrinology, vol.2015, p.826249, 2015.

T. J. Varcoe, N. Wight, A. Voultsios, D. Mark, D. J. Salkeld et al., Chronic Phase Shifts of the Photoperiod throughout Pregnancy Programs Glucose Intolerance and Insulin Resistance in the Rat, PloS One, vol.6, issue.4, 2011.

B. Vida, . Deli, . Hrabovszky, . Kalamatianos, C. Caraty et al., Evidence for Suprachiasmatic Vasopressin Neurones Innervating Kisspeptin Neurones in the Rostral Periventricular Area of the Mouse Brain: Regulation by Oestrogen, Journal of Neuroendocrinology, vol.22, issue.9, pp.1032-1071, 2010.
URL : https://hal.archives-ouvertes.fr/hal-01129478

,

M. V. Vyas, X. Amit, A. V. Garg, J. Iansavichus, A. Costella et al., Shift Work and Vascular Events: Systematic Review and Meta-Analysis, Clinical Research Ed.), vol.345, issue.jul26_1, p.4800, 2012.

. Wan, F. Gwo-hwa, and . Chung, Working Conditions Associated with Ovarian Cycle in a Medical Center Nurses: A Taiwan Study, Japan Journal of Nursing Science : JJNS, vol.9, issue.1, pp.112-130, 2012.

F. Wang, M. Gu, L. Deng, C. Guo, C. Lu et al., Rotating Shift Work and Menstrual Characteristics in a Cohort of Chinese Nurses, BMC Women's Health, vol.16, issue.1, p.24, 2016.

H. Wang, H. Masironi, L. Eriksson, and . Sahlin, A Comparative Study of Estrogen Receptors Alpha and Beta in the Rat Uterus, Biology of Reproduction, vol.61, issue.4, pp.955-64, 1999.

M. Watanabe, A. Fukuda, and J. Nabekura, The Role of GABA in the Regulation of GnRH Neurons, Frontiers in Neuroscience, vol.8, p.387, 2014.

L. Weibel and G. Brandenberger, The Start of the Quiescent Period of Cortisol Remains Phase Locked to the Melatonin Onset despite Circadian Phase Alterations in Humans Working the Night Schedule, Neuroscience Letters, vol.318, issue.2, pp.89-92, 2002.

C. Weinberg, D. Baird, and A. Wilcox, Sources of Bias in Studies of Time to Pregnancy, Statistics in Medicine, vol.13, issue.5-7, pp.671-81, 1994.

S. Whirledge and J. A. Cidlowski, A Role for Glucocorticoids in Stress-Impaired Reproduction: Beyond the Hypothalamus and Pituitary, Endocrinology, vol.154, issue.12, pp.4450-68, 2013.

J. White, M. Herschman, G. Parmar, K. A-philipson, M. Elder et al., Activated Oestrogen Receptor in Human Breast Cancer: Clinical and Biochemical Correlates, The British Journal of Surgery, vol.74, issue.7, pp.588-90, 1987.

S. Wiegand, W. Terasawa, R. E-bridson, and . Goy, Effects of Discrete Lesions of Preoptic and Suprachiasmatic Structures in the Female Rat. Alterations in the Feedback Regulation of Gonadotropin Secretion, Neuroendocrinology, vol.31, issue.2, pp.147-57, 1980.

W. P. Williams, G. Stephan, J. D. Jarjisian, L. J. Mikkelsen, and . Kriegsfeld, Circadian Control of Kisspeptin and a Gated GnRH Response Mediate the Preovulatory Luteinizing Hormone Surge, Endocrinology, vol.152, issue.2, pp.595-606, 2011.

,

W. P. Williams and L. J. Kriegsfeld, Circadian Control of Neuroendocrine Circuits Regulating Female Reproductive Function, Frontiers in Endocrinology, vol.3, p.60, 2012.

T. M. Wintermantel, R. E. Campbell, R. Porteous, D. Bock, H. Gröne et al., Definition of Estrogen Receptor Pathway Critical for Estrogen Positive Feedback to Gonadotropin-Releasing Hormone Neurons and Fertility, Neuron, vol.52, issue.2, pp.271-80, 2006.

,

A. Wolfe and S. Wu, Estrogen Receptor-? in the Gonadotropin-Releasing Hormone Neuron, Seminars in Reproductive Medicine, vol.30, issue.1, pp.23-31, 2012.

,

S. Wu, H. Zhang, J. Tian, L. Liu, Y. Dong et al., Expression of Kisspeptin/GPR54 and PIBF/PR in the First Trimester Trophoblast and Decidua of Women with Recurrent Spontaneous Abortion, Pathology, Research and Practice, vol.210, issue.1, pp.47-54, 2014.

J. Xu, M. A. Kirigiti, A. Michael, K. L. Cowley, M. Grove et al., Suppression of Basal Spontaneous Gonadotropin-Releasing Hormone Neuronal Activity during Lactation: Role of Inhibitory Effects of Neuropeptide Y, Endocrinology, vol.150, issue.1, pp.333-373, 2009.

B. Yang, Q. Jiang, T. Chan, K. Wendy, A. Ko et al., Goldfish Kisspeptin: Molecular Cloning, Tissue Distribution of Transcript Expression, and Stimulatory Effects on Prolactin, Growth Hormone and Luteinizing Hormone Secretion and Gene Expression via Direct Actions at the Pituitary Level, General and Comparative Endocrinology, vol.165, issue.1, pp.60-71, 2010.

H. Ye, J. U. Hui, M. J. Jeong, J. Jeon, and . Sakong, The Association between Shift Work and the Metabolic Syndrome in Female Workers, Annals of Occupational and Environmental Medicine, vol.25, issue.1, p.33, 2013.

H. Yip, U. Boehm, A. E. Herbison, and R. E. Campbell, Conditional Viral Tract-Tracing Delineates the Projections of the Distinct Kisspeptin Neuron Populations to Gonadotropin-Releasing Hormone (GnRH) Neurons in the Mouse, Endocrinology, 2015.

S. Yoo, S. Yamazaki, L. Phillip, K. Lowrey, C. H. Shimomura et al., PERIOD2::LUCIFERASE Real-Time Reporting of Circadian Dynamics Reveals Persistent Circadian Oscillations in Mouse Peripheral Tissues, Proceedings of the National Academy of Sciences of the United States of America, vol.101, issue.15, pp.5339-5385, 2004.

K. Yoshinaka, A. Yamaguchi, R. Matsumura, K. Node, I. Tokuda et al., Effect of Different Light-Dark Schedules on Estrous Cycle in Mice, and Implications for Mitigating the Adverse Impact of Night Work, Genes to Cells : Devoted to Molecular & Cellular Mechanisms, vol.22, issue.10, pp.876-84, 2017.

J. Young, J. Bouligand, B. Francou, M. Raffin-sanson, S. Gaillez et al., TAC3 and TACR3 Defects Cause Hypothalamic Congenital Hypogonadotropic Hypogonadism in Humans, The Journal of Clinical Endocrinology and Metabolism, vol.95, issue.5, pp.2287-95, 2010.

,

J. Young, T. Jyothis, J. A. George, B. Tello, J. Francou et al., Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies: Physiological, Pathophysiological and Therapeutic Implications, Neuroendocrinology, vol.97, issue.2, pp.193-202, 2013.

J. Zhu, N. Hjollund, H. Boggild, and J. Olsen, Shift Work and Subfecundity: A Causal Link or an Artefact?, Occupational and Environmental Medicine, vol.60, issue.9, p.12, 2003.