, mRNA without cap-structure and poly(A)-tail: a cryo electron tomography study, Nucleic Acids Res, vol.42, pp.9461-9469
Toward automated crystallographic structure refinement with phenix.refine, Acta Cryst, vol.68, pp.352-367, 2012. ,
Atomic model of the F420-reducing [NiFe] hydrogenase by electron cryo-microscopy using a direct electron detector, Elife, vol.3, p.1963, 2014. ,
SharpViSu: integrated analysis and segmentation of super-resolution microscopy data, Bioinformatics, vol.32, pp.2239-2241, 2016. ,
ClusterViSu, a method for clustering of protein complexes by Voronoi tessellation in super-resolution microscopy, Sci. Rep, vol.6, p.24084, 2016. ,
Site-Specific Cryo-focused Ion Beam Sample Preparation Guided by 3D Correlative Microscopy, Biophys. J, vol.110, pp.860-869, 2016. ,
, Situ Cryo-Electron Tomography: A Post-Reductionist Approach to Structural Biology, vol.428, pp.332-343, 2016.
Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles, vol.2, p.461, 2013. ,
Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy, J. Am. Chem. Soc, vol.132, pp.16352-163523, 2010. ,
) 2.3Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition, Science, vol.351, pp.871-875, 2016. ,
EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy, Nat. Methods, vol.12, pp.943-946, 2015. ,
Nuclear pore complex structure and dynamics revealed by cryoelectron tomography, Science, vol.306, pp.1387-1390, 2004. ,
IBiSS, a versatile and interactive tool for integrated sequence and 3D structure analysis of large macromolecular complexes, Bioinformatics, vol.31, pp.3339-3344, 2015. ,
Crystal structure of the eukaryotic ribosome, Science, vol.330, pp.1203-1209, 2010. ,
The three-dimensional organization of polyribosomes in intact human cells, Mol. Cell, vol.39, pp.560-569, 2010. ,
Structural biology in situ -the potential of subtomogram averaging, Curr. Opin. Struct. Biol, vol.23, pp.261-267, 2013. ,
Beam-induced motion of vitrified specimen on holey carbon film, J. Struct. Biol, vol.177, pp.630-637, 2012. ,
The PILATUS 1M detector, J. Synchrotron Radiat, vol.13, pp.120-130, 2006. ,
Tools for macromolecular model building and refinement into electron cryo-microscopy reconstructions, 2015. ,
, Acta Crystallogr. D Biol. Crystallogr, vol.71, pp.136-153
Movies of ice-embedded particles enhance resolution in electron cryo-microscopy, Structure, vol.20, pp.1823-1828, 2012. ,
Three-dimensional reconstruction methods in Single Particle Analysis from transmission electron microscopy data, Arch. Biochem. Biophys, vol.581, pp.39-48, 2015. ,
Cryo electron microscopy to determine the structure of macromolecular complexes, Methods, vol.95, pp.78-85, 2016. ,
EIGER detector: application in macromolecular crystallography, Acta Crystallogr. D Struct. Biol, vol.72, pp.1036-1048, 2016. ,
Dynamo Catalogue: Geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms, J. Struct. Biol, vol.16, pp.30111-30113, 2016. ,
Architecture of the type IVa pilus machine, Science, vol.351, p.2001, 2016. ,
Structural dynamics of ribosome subunit association studied by mixing-spraying time-resolved cryogenic electron microscopy, Structure, vol.23, pp.1097-1105, 2015. ,
Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM, Proc. Natl. Acad. Sci. U.S.A, vol.106, pp.10644-10648, 2009. ,
Autofocused 3D classification of cryoelectron subtomograms, Structure, vol.22, pp.1528-1537, 2014. ,
) 3.9Å structure of the nucleosome core particle determined by phase-plate cryo-EM, Nucleic Acids Res, vol.44, pp.8013-8019, 2016. ,
Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages, Nat. Protoc, vol.9, pp.2630-2642, 2014. ,
Cryo-EM single particle analysis with the Volta phase plate, Elife, vol.5, p.13046, 2016. ,
Volta potential phase plate for in-focus phase contrast transmission electron microscopy, Proc. Natl Acad. Sci. U.S.A, vol.44, pp.15635-15640, 2014. ,
Cryo-electron microscopy of vitrified specimens, Q. Rev. Biophys, vol.21, pp.129-228, 1988. ,
Developments in cryo-electron tomography for in situ structural analysis, Arch. Biochem. Biophys, vol.581, pp.78-85, 2015. ,
Imaging of organelles by electron microscopy reveals protein-protein interactions in mitochondria and chloroplasts, FEBS Lett, vol.584, pp.2510-2515, 2010. ,
, www.biolcell.net | Volume (109) | Pages, pp.81-93
Cryo-EM of viruses and vaccine design, Integrative role of cryo-EM in structural biology Review Earl, vol.113, pp.8903-8905, 2016. ,
IF2 Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases, Proc. Nat. Acad. Sci. U.S.A, vol.110, pp.15662-15667, 2013. ,
Features and development of Coot, Acta Crystallogr. D Biol. Crystallogr, vol.66, pp.486-501, 2010. ,
Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy, Nature, vol.466, pp.329-333, 2010. ,
Structure of the E. coli ribosome-EF-Tu complex at <3Å resolution by Cs-corrected cryo-EM, Nature, vol.520, pp.567-570, 2015. ,
Identification of macromolecular complexes in cryoelectron tomograms of phantom cells, Proc. Natl. Acad. Sci. U.S.A, vol.99, pp.14153-14158, 2002. ,
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging, J. Struct. Biol, vol.178, pp.165-176, 2012. ,
In-focus electrostatic Zach phase plate imaging for transmission electron microscopy with tunable phase contrast of frozen hydrated biological samples, Microsc. Microanal, vol.1, pp.175-183, 2014. ,
Unsupervised classification of single particles by cluster tracking in multi-dimensional space, J. Struct. Biol, vol.157, pp.226-239, 2006. ,
Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography, J. Struct. Biol, vol.194, pp.383-394, 2016. ,
Dynamics of EF-G interaction with the ribosome explored by classification of a heterogeneous cryo-EM dataset, J. Struct. Biol, vol.147, pp.283-290, 2004. ,
Protein complexes in focus, Elife, vol.5, 2016. ,
Measuring the optimal exposure for single particle cryo-EM using a 2.6Å reconstruction of rotavirus VP6, vol.4, p.6980, 2015. ,
The complete structure of the 55S mammalian mitochondrial ribosome, Science, vol.348, pp.303-308, 2015. ,
, Cell, vol.163, pp.1692-1701, 2015.
Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging, J. Struct. Biol, vol.16, pp.30113-30117, 2016. ,
Clustering and variance maps for cryo-electron tomography using wedge-masked differences, J. Struct. Biol, vol.175, pp.288-299, 2011. ,
Cellular structural biology as revealed by cryo-electron tomography, J. Cell Sci, vol.129, pp.469-476, 2016. ,
Fast and precise targeting of single tumor cells in vivo by multimodal correlative microscopy, J. Cell Sci, vol.129, pp.444-456, 2016. ,
Purification, characterization and crystallization of the human 80S ribosome, Nucleic Acids Res, vol.42, pp.1-11, 2014. ,
Structure of the human 80S ribosome, Nature, vol.520, pp.640-645, 2015. ,
Subtomogram analysis using the Volta phase plate, J. Struct. Biol, vol.16, pp.30103-30104, 2016. ,
Volta phase plate cryo-EM of the small protein complex Prx3, Nat. Commun, vol.7, p.10534, 2016. ,
Correlative stochastic optical reconstruction microscopy and electron microscopy, PLoS One, vol.10, 2015. ,
Focused ion beam scanning electron microscopy in biology, J. Microsc, vol.254, pp.109-114, 2014. ,
Structure sorting of multiple macromolecular states in heterogeneous cryo-EM samples by 3D multivariate statistical analysis, Open J. Stat, vol.5, pp.820-836, 2015. ,
Visualization of release factor 3 on the ribosome during termination of protein synthesis, Nature, vol.427, pp.862-865, 2004. ,
Correlative cryo-fluorescence light microscopy and cryo-electron tomography of Streptomyces, Methods Cell Biol, vol.124, pp.217-239, 2014. ,
Molecular architecture of the inner ring scaffold of the human nuclear pore complex, Science, vol.352, pp.363-365, 2016. ,
FEI's direct electron detector developments: Embarking on a revolution in cryo-TEM, J. Struct. Biol, vol.192, pp.179-187, 2015. ,
Time-resolved low-dose microscopy of glutamine synthetase molecules, Ultramicroscopy, vol.13, pp.241-252, 1984. ,
Collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography, J. Struct. Biol, vol.181, pp.116-127, 2013. ,
Structural analysis of herpes simplex virus by optical super-resolution imaging, Nat. Commun, vol.6, p.5980, 2015. ,
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM, Nat. Methods, vol.10, pp.584-590, 2013. ,
Efficient estimation of three-dimensional covariance and its application in the analysis of heterogeneous samples in cryo-electron microscopy, Structure, vol.23, pp.1129-1237, 2015. ,
, , vol.352, p.6283, 2016.
Correlative super-resolution fluorescence and electron microscopy of the nuclear pore complex with molecular resolution, J. Cell Sci, vol.127, pp.4351-4355, 2014. ,
Cryo-electron tomography: the challenge of doing structural biology in situ, J. Cell Biol, vol.202, pp.407-419, 2013. ,
Likelihood-based classification of cryo-EM images using FREALIGN, J. Struct. Biol, vol.183, pp.377-388, 2013. ,
Visualizing the molecular sociology at the HeLa cell nuclear periphery, Science, vol.351, pp.969-972, 2016. ,
A focused ion beam milling and lift-out approach for site-specific preparation of frozen-hydrated lamellas from multicellular organisms, J. Struct. Biol, vol.192, pp.262-269, 2015. ,
The palindromic DNA-bound USP/EcR nuclear receptor adopts an asymmetric organization with allosteric domain positioning, Nat. Commun, vol.5, p.4139, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-02640131
Detective quantum efficiency of electron area detectors in electron microscopy, Ultramicroscopy, vol.109, pp.1126-1143, 2009. ,
Comparison of optimal performance at 300keV of three direct electron detectors for use in low dose electron microscopy, Ultramicroscopy, vol.147, pp.156-163, 2014. ,
Macromolecular architecture in eukaryotic cells visualized by cryoelectron tomography, Science, vol.298, pp.1209-1213, 2002. ,
Integrative structure-function analysis of large nucleoprotein complexes, 2013. ,
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery, Cell, vol.165, pp.1698-1707, 2016. ,
Cryo-electron microscopy -a primer for the non-microscopist, FEBS J, vol.280, pp.28-45, 2013. ,
Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions, Structure, vol.18, pp.903-912, 2010. ,
The molecular structure of the left-handed supra-molecular helix of eukaryotic polyribosomes, Nat. Commun, vol.5, p.5294, 2014. ,
Single particle and molecular assembly analysis of polyribosomes by single-and double-tilt cryo electron tomography, Ultramicroscopy, vol.126, pp.33-39, 2013. ,
Structure-function insights reveal the human ribosome as a cancer target for antibiotics, Nat. Commun, vol.7, p.12856, 2016. ,
Structure of a bacterial type III secretion system in contact with a host membrane in situ, Nat. Commun, vol.6, p.10114, 2015. ,
Imaging protein three-dimensional nanocrystals with cryo-EM, Acta Crystallogr. D Biol. Crystallogr, vol.69, pp.852-859, 2013. ,
A simple and fast approach for missing-wedge invariant classification of subtomograms extracted from filamentous structures, J. Struct. Biol, vol.16, p.30172, 2016. ,
Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA, EMBO J, vol.31, pp.291-300, 2012. ,
Live cell immunogold labelling of RNA polymerase II, Sci. Rep, vol.5, p.8324, 2015. ,
Methods for three-dimensional reconstruction of heterogeneous assemblies, Methods Enzymol, vol.482, pp.321-362, 2010. ,
Mapping 70S ribosomes in intact cells by cryoelectron tomography and pattern recognition, J. Struct. Biol, vol.156, pp.334-341, 2006. ,
A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation, J. Struct. Biol, vol.154, pp.184-194, 2006. ,
Radiation damage in room-temperature data acquisition with the PILATUS 6M pixel detector, J. Synchrotron Radiat, vol.18, pp.318-328, 2011. ,
Determination of Escherichia coli RNA polymerase structure by single particle cryoelectron microscopy, Methods Enzymol, vol.370, pp.24-42, 2003. ,
A new method for vitrifying samples for cryoEM, J. Struct. Biol, vol.195, pp.190-198, 2016. ,
Towards an optimum design for thin film phase plates, Ultramicroscopy, vol.160, pp.1-6, 2016. ,
Cryo-focused-ion-beam applications in structural biology, Arch. Biochem. Biophys, vol.581, pp.122-130, 2015. ,
Quantitative characterization of electron detectors for transmission electron microscopy, J. Struct. Biol, vol.184, pp.385-393, 2013. ,
Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED, Proc. Natl. Acad. Sci. U.S.A, p.201606287, 2016. ,
Optimized cryo-focused ion beam sample preparation aimed at in situ structural studies of membrane proteins, J. Struct. Biol, vol.16, pp.30151-30154, 2016. ,
Maximum likelihood multi-reference refinement for electron microscopy images, J. Mol. Biol, vol.22, pp.139-149, 2005. ,
Classification of structural heterogeneity by maximum-likelihood methods, Methods Enzymol, vol.482, pp.295-320, 2010. ,
Beam-induced motion correction for sub-megadalton cryo-EM particles, Elife, vol.3, p.3665, 2014. ,
Correlative fluorescence and electron microscopy, Curr. Protoc. Cytom, vol.70, pp.1-10, 2014. ,
New hardware and workflows for semi-automated correlative cryo-fluoresence and cryo-electron microscopy/tomography, J. Struct. Biol, vol.16, pp.30135-30136, 2016. ,
, An 92 www.biolcell.net | Volume (109) | Pages, pp.81-93, 2016.
The collection of MicroED data for macromolecular crystallography, Nat. Protoc, vol.11, pp.895-904, 2016. ,
A maximum-likelihood approach to single-particle image refinement, J. Struct. Biol, vol.122, pp.328-339, 1998. ,
Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms, Acta Cryst, vol.69, pp.925-933, 2013. ,
Involvement of IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor, Proc. Nat. Acad. Sci. U.S.A, vol.110, pp.15656-15661, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02645085
Ribosomal 18S rRNA base pairs with mRNA during eukaryotic translation initiation, Nat. Commun, vol.7, p.12622, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02294260
Structure of the 30S translation initiation complex, Nature, vol.455, pp.416-420, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-00342095
Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER, Acta Crystallogr. D Biol. Crystallogr, vol.68, pp.368-380, 2012. ,
Programming new geometry restraints: parallelity of atomic groups, J. Appl. Crystallogr, vol.48, pp.1130-1141, 2015. ,
The influence of frame alignment with dose compensation on the quality of single particle reconstructions, J. Struct. Biol, vol.192, pp.196-203, 2015. ,
CryoEM structure of the lactococcal siphophage 1358 virion, J. Virol, vol.88, pp.8900-8910, 2014. ,
Maximum likelihood based classification of electron tomographic data, J. Struct. Biol, vol.173, pp.77-85, 2011. ,
Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging, Science, vol.341, pp.655-658, 2013. ,
Single-particle electron cryo-microscopy: towards atomic resolution, Microscopy (Oxf.), vol.65, pp.307-369, 2000. ,
Maximizing the potential of electron cryomicroscopy data collected using direct detectors, J. Struct. Biol, vol.184, pp.193-202, 2013. ,
Opening windows into the cell: focused-ion-beam milling for cryo-electron tomography, Curr. Opin. Struct. Biol, vol.23, pp.771-777, 2013. ,
Towards an optimum design for electrostatic phase plates, Ultramicroscopy, vol.153, pp.22-31, 2015. ,
Cryo-electron tomography and subtomogram averaging, Methods Enzymol, vol.579, pp.329-367, 2016. ,
In vivo virus structures: simultaneous classification, resolution enhancement, and noise reduction in whole-cell electron tomography, J. Struct. Biol, vol.174, pp.425-433, 2011. ,
Recognition and separation of single particles with size variation by statistical analysis of their images, J. Mol. Biol, vol.13, pp.453-460, 2004. ,
, Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife 3, 2014.
Automated target segmentation and real space fast alignment methods for high-throughput classification and averaging of crowded cryo-electron subtomograms, Bioinformatics, vol.29, pp.274-282, 2013. ,
UCSF Chimera, MODELLER, and IMP: an integrated modeling system, J. Struct. Biol, vol.179, pp.269-278, 2012. ,
An improved cryo-FIB method for fabrication of frozen hydrated lamella, J. Struct. Biol, vol.194, pp.218-223, 2016. ,
Cryo-EM structure of the mature dengue virus at 3.5-Å resolution, Nat. Struct. Mol. Biol, vol.20, pp.105-110, 2013. ,
,
NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p, EMBO J, vol.18, pp.5108-5119, 1999. ,
The NuRD architecture, Cell. Mol. Life Sci, vol.70, pp.3513-3524, 2013. ,
Structural Modifications of Histones and their Possible Role in the Regulation of RNA Synthesis, Science, vol.144, p.559, 1964. ,
Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX, Journal of Biological Chemistry, vol.289, pp.21844-21855, 2014. ,
Dynamics and Context-Dependent Roles of DNA Methylation, J. Mol. Biol, vol.429, pp.1459-1475, 2017. ,
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2, Nat. Genet, vol.23, pp.185-188, 1999. ,
Recognition of hemimethylated DNA by the SRA protein UHRF1 by a base-flipping mechanism, Nature, vol.455, pp.818-821, 2008. ,
Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution, Science, vol.334, pp.977-982, 2011. ,
Histone deacetylases: transcriptional repression with SINers and NuRDs, Trends Cell Biol, vol.9, pp.193-198, 1999. ,
An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders, Cell, vol.152, pp.984-996, 2013. ,
CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L, Hum. Mol. Genet, vol.14, pp.513-524, 2005. ,
Isolation of human NURF: a regulator of Engrailed gene expression, EMBO J, vol.22, pp.6089-6100, 2003. ,
, Atomic Resolution Cryo-EM Structure of ?-Galactosidase, vol.26, pp.848-856, 2018.
The nucleosome remodeling and deacetylase complex in development and disease, Transl Res, vol.165, pp.36-47, 2015. ,
Methylation-dependent and -independent genomic targeting principles of the MBD protein family, Cell, vol.153, pp.480-492, 2013. ,
Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1, Molecular Cell, vol.66, pp.384-397, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01537811
Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesis, PLoS ONE, vol.9, p.98203, 2014. ,
Crystallization of biological macromolecules using agarose gel, Acta Crystallographica Section D Biological Crystallography, vol.58, pp.1657-1659, 2002. ,
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells, Science, vol.317, pp.1760-1764, 2007. ,
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability, Nat. Rev. Mol. Cell Biol, vol.5, pp.2888-2902, 1995. ,
Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3, J. Biol. Chem, vol.277, pp.40958-40966, 2002. ,
p66alpha and p66beta of the Mi-2/NuRD complex mediate MBD2 and histone interaction, Nucleic Acids Res, vol.34, pp.397-406, 2006. ,
INO80 exchanges H2A.Z for H2A by translocating on DNA proximal to histone dimers, Nat Commun, vol.8, p.15616, 2017. ,
Density Gradient Centrifugation: A New Separation Technique 1, Journal of the American Chemical Society, vol.73, pp.1847-1848, 1951. ,
Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation, Biochim. Biophys. Acta, vol.1865, pp.843-851, 1996. ,
Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation, Int. J. Dev. Biol, vol.53, pp.275-289, 2009. ,
Kaiso uses all three zinc fingers and adjacent sequence motifs for high affinity binding to sequence-specific and methyl-CpG DNA targets, FEBS Lett, vol.586, pp.734-739, 2012. ,
The BAH (bromo-adjacent homology) domain: a link between DNA methylation, replication and transcriptional regulation, FEBS Lett, vol.446, pp.189-193, 1999. ,
Histone deacetylase HDAC1 expression correlates with the progression and prognosis of lung cancer, Medicine, p.96, 2017. ,
MeCP2, a key contributor to neurological disease, activates and represses transcription, Science, vol.320, pp.1224-1229, 2008. ,
A/T Run Geometry of Bform DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence. Scientific Reports, vol.6, 2016. ,
The use of trehalose in the preparation of specimens for molecular electron microscopy, Micron, vol.42, pp.762-772, 2011. ,
The biology of chromatin remodeling complexes, Annu. Rev. Biochem, vol.78, pp.273-304, 2009. ,
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes, Nat. Rev. Mol. Cell Biol, vol.18, pp.407-422, 2017. ,
Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA, Nucleic Acids Research, vol.38, pp.4620-4634, 2010. ,
Modulation of ISWI function by site-specific histone acetylation, EMBO Rep, vol.3, pp.242-247, 2002. ,
Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA, J Biol Chem, vol.289, pp.1294-1302, 2014. ,
The expanding role of MBD genes in autism: identification of a MECP2 duplication and novel alterations in MBD5, MBD6, and SETDB1, Autism Res, vol.5, pp.385-397, 2012. ,
Unexpected property of trehalose as observed by cryo-electron microscopy: unexpected property of trehalose as observed by cryo-electron microscopy, Journal of Microscopy, vol.196, pp.40-45, 1999. ,
Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing, PLoS ONE, vol.8, pp.887-896, 2013. ,
The human Mi-2/NuRD complex and gene regulation, Oncogene, vol.26, pp.5433-5438, 2007. ,
An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex, Nucleic Acids Res, vol.43, pp.3100-3113, 2015. ,
MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner, Cell Stem Cell, vol.15, pp.102-110, 2014. ,
Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors ?, ? . Biochemistry, vol.47, pp.13554-13563, 2008. ,
Fast and sensitive colloidal coomassie G-250 staining for proteins in polyacrylamide gels, J Vis Exp, 2009. ,
Structural basis for ATP-dependent chromatin remodelling by the INO80 complex, Nature, vol.556, pp.386-390, 2018. ,
Identification and functional characterization of the p66/p68 components of the MeCP1 complex, Mol. Cell. Biol, vol.22, pp.536-546, 2002. ,
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors, Nature, vol.401, pp.188-193, 1999. ,
Isolation and characterization of a novel class II histone deacetylase, HDAC10, J. Biol. Chem, vol.277, pp.6656-6666, 2002. ,
LSD1: oxidative chemistry for multifaceted functions in chromatin regulation, Trends Biochem. Sci, vol.33, pp.181-189, 2008. ,
The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties, Nucleic Acids Res, vol.31, pp.1765-1774, 2003. ,
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity, Biochem. Biophys. Res. Commun, vol.260, pp.273-279, 1999. ,
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis, Cell Research, vol.21, pp.275-289, 2011. ,
Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family, J. Biol. Chem, vol.277, pp.25748-25755, 2002. ,
p66Alpha-MBD2 coiledcoil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex, Proc. Natl. Acad. Sci. U.S.A, vol.108, pp.7487-7492, 2011. ,
Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair, J Cell Biol, vol.216, pp.1959-1974, 2017. ,
SUMO Modification Enhances p66-Mediated Transcriptional Repression of the Mi-2/NuRD Complex, Molecular and Cellular Biology, vol.26, pp.4519-4528, 2006. ,
Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis, J. Mol. Biol, vol.338, pp.17-31, 2004. ,
Three proteins define a class of human histone deacetylases related to yeast Hda1p, Proc. Natl. Acad. Sci. U.S.A, vol.96, pp.4868-4873, 1999. ,
Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences, Nucleic Acids Res, vol.41, pp.3010-3021, 2013. ,
A chromatin remodelling complex that loads cohesin onto human chromosomes, Nature, vol.418, pp.994-998, 2002. ,
Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity, Cancer Res, vol.67, pp.3145-3152, 2007. ,
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix, Nature, vol.455, pp.826-829, 2008. ,
Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation, Nucleic Acids Res, vol.40, pp.8276-8284, 2012. ,
GraDeR: Membrane Protein Complex Preparation for Single-Particle Cryo-EM, Structure, vol.23, pp.1769-1775, 2015. ,
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA, Science, vol.333, pp.1303-1307, 2011. ,
Identification and characterization of a family of mammalian methyl-CpG binding proteins, Mol. Cell. Biol, vol.18, pp.6538-6547, 1998. ,
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development, Genes Dev, vol.15, pp.710-723, 2001. ,
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites, Nature, vol.401, pp.301-304, 1999. ,
The methyl-CpG binding domain and the evolving role of DNA methylation in animals, Trends Genet, vol.19, pp.269-277, 2003. ,
MeCP2 binding to DNA depends upon hydration at methyl-CpG, Mol. Cell, vol.29, pp.525-531, 2008. ,
Formaldehyde crosslinking: a tool for the study of chromatin complexes, J. Biol. Chem, vol.290, pp.26404-26411, 2015. ,
CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality, Nucleic Acids Research, vol.45, pp.10534-10554, 2017. ,
The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography, J. Biol. Chem, vol.175, pp.315-332, 1948. ,
, , vol.449, pp.105-108, 2007.
Enzymatic deacetylation of histone, Biochem. Biophys. Res. Commun, vol.36, pp.146-150, 1969. ,
Spotiton: A prototype for an integrated inkjet dispense and vitrification system for cryo-TEM, Journal of Structural Biology, vol.179, pp.68-75, 2012. ,
Acetylation-and Methylation-Related Epigenetic Proteins in the Context of Their Targets, Genes, 2017. ,
Mbd1 Is Recruited to both Methylated and Nonmethylated CpGs via Distinct DNA Binding Domains, Molecular and Cellular Biology, vol.24, pp.3387-3395, 2004. ,
Structure of p300 in complex with acyl-CoA variants, Nature Chemical Biology, vol.13, pp.21-29, 2017. ,
Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence, Cancer Res, vol.66, pp.11341-11347, 2006. ,
Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells, Development, vol.134, pp.1123-1132, 2007. ,
Isolation and characterization of mammalian HDAC10, a novel histone deacetylase, J. Biol. Chem, vol.277, pp.187-193, 2002. ,
Evidence for monomeric actin function in INO80 chromatin remodeling, Nat Struct Mol Biol, vol.20, pp.426-432, 2013. ,
Mechanisms of Nuclear Actin in Chromatin Remodeling Complexes, Trends Cell Biol, vol.24, pp.238-246, 2014. ,
The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny, Development, vol.134, pp.1571-1582, 2007. ,
The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts, Biochem. Soc. Trans, vol.41, pp.741-749, 2013. ,
Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes, Immunity, vol.10, pp.345-355, 1999. ,
Towards elucidating the stability, dynamics and architecture of the nucleosome remodeling and deacetylase complex by using quantitative interaction proteomics, FEBS Journal, vol.282, pp.1774-1785, 2015. ,
DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG, Mol. Cell, vol.19, pp.667-678, 2005. ,
KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes, Proc. Natl. Acad. Sci. U.S.A, vol.111, pp.15078-15083, 2014. ,
Roles of histone acetyltransferases and deacetylases in gene regulation, Bioessays, vol.20, pp.615-626, 1998. ,
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein, Genes Dev, vol.16, pp.2893-2905, 2002. ,
Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF, 2003. ,
Cancer biology and NuRD: a multifaceted chromatin remodelling complex, Nat. Rev. Cancer, vol.11, pp.588-596, 2011. ,
A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex, J. Biol. Chem, vol.281, pp.23922-23931, 2006. ,
Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability, Journal of Biological Chemistry, vol.288, pp.26926-26943, 2013. ,
MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties, Mol. Cell. Biol, vol.26, pp.843-851, 2006. ,
Functional Interplay between Histone Demethylase and Deacetylase Enzymes, Molecular and Cellular Biology, vol.26, pp.6395-6402, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00171607
Functional interplay between histone demethylase and deacetylase enzymes, Mol. Cell. Biol, vol.26, pp.6395-6402, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00171607
An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation, Nature, vol.437, pp.432-435, 2005. ,
Histone deacetylases, acetoin utilization proteins and acetylpolyamine amidohydrolases are members of an ancient protein superfamily, Nucleic Acids Res, vol.25, pp.3693-3697, 1997. ,
Insights into Association of the NuRD Complex with FOG-1 from the Crystal Structure of an RbAp48·FOG-1 Complex, Journal of Biological Chemistry, vol.286, pp.1196-1203, 2011. ,
The SRC family of nuclear receptor coactivators, Gene, vol.245, pp.1-11, 2000. ,
The role of chromatin during transcription, Cell, vol.128, pp.707-719, 2007. ,
Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA, J. Biol. Chem, vol.293, pp.7344-7354, 2018. ,
IBS: an illustrator for the presentation and visualization of biological sequences: Fig. 1, Bioinformatics, vol.31, pp.3359-3361, 2015. ,
Histone octamer transfer by a chromatin-remodeling complex, Cell, vol.96, pp.389-392, 1999. ,
CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex, J. Biol. Chem, vol.291, pp.15853-15866, 2016. ,
Sequence-specific DNA binding by AT-hook motifs in MeCP2, FEBS Letters, vol.590, pp.2927-2933, 2016. ,
HDAC1 and HDAC2 in mouse oocytes and preimplantation embryos: Specificity versus compensation, Cell Death Differ, vol.23, pp.1119-1127, 2016. ,
Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9, J. Biol. Chem, vol.286, pp.11779-11791, 2011. ,
Histone modifying enzymes: structures, mechanisms, and specificities, Biochim. Biophys. Acta, vol.1789, pp.58-68, 2009. ,
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs, Cell, vol.58, pp.499-507, 1989. ,
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery, Cell, vol.165, pp.1698-1707, 2016. ,
Towards an understanding of the structure and function of MTA1, Cancer Metastasis Rev, vol.33, pp.857-867, 2014. ,
The structure of the core NuRD repression complex provides insights into its interaction with chromatin, 2016. ,
Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates, Molecular Cell, vol.51, pp.57-67, 2013. ,
DOC1-Dependent Recruitment of NURD Reveals Antagonism with SWI/SNF during Epithelial-Mesenchymal Transition in Oral Cancer Cells, Cell Reports, vol.20, pp.61-75, 2017. ,
NIRF, a novel RING finger protein, is involved in cell-cycle regulation, Biochem. Biophys. Res. Commun, vol.296, pp.530-536, 2002. ,
Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46, Structure, vol.16, pp.1077-1085, 2008. ,
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications, Biochem. J, vol.423, pp.179-187, 2009. ,
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression, Proc. Natl. Acad. Sci. U.S.A, vol.109, pp.787-792, 2012. ,
A core chromatin remodeling factor instructs global chromatin signaling through multivalent reading of nucleosome codes, Mol. Cell, vol.49, pp.704-718, 2013. ,
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2, Nucleic Acids Research, vol.21, pp.4886-4892, 1993. ,
Visualization of chemical modifications in the human 80S ribosome structure, Nature, 2017. ,
URL : https://hal.archives-ouvertes.fr/inserm-02409680
A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development, Cell Rep, vol.17, pp.1683-1698, 2016. ,
Chfr is linked to tumour metastasis through the downregulation of HDAC1, Nat. Cell Biol, vol.11, pp.295-302, 2009. ,
Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA, Cell, vol.105, pp.487-497, 2001. ,
The integrative role of cryo electron microscopy in molecular and cellular structural biology: Integrative role of cryo-EM in structural biology, Biology of the Cell, vol.109, pp.81-93, 2017. ,
Structural Basis of the Versatile DNA Recognition Ability of the Methyl-CpG Binding Domain of Methyl-CpG Binding Domain Protein 4, J. Biol. Chem, vol.288, pp.6351-6362, 2013. ,
Graphene oxide: A substrate for optimizing preparations of frozen-hydrated samples, Journal of Structural Biology, vol.170, pp.152-156, 2010. ,
The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism, Cell, vol.87, pp.85-94, 1996. ,
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor, Genes Dev, vol.15, pp.1613-1618, 2001. ,
A retinoblastoma-binding protein related to a negative regulator of Ras in yeast, Nature, vol.364, pp.648-652, 1993. ,
Tumoricidal activities of pterostilbene depend upon destabilizing the MTA1-NuRD complex and enhancing P53 acetylation in hepatocellular carcinoma, Exp Ther Med, vol.14, pp.3098-3104, 2017. ,
Deterministic direct reprogramming of somatic cells to pluripotency, Nature, vol.502, pp.65-70, 2013. ,
Drosophila Transcription Factor Tramtrack69 Binds MEP1 To Recruit the, Chromatin Remodeler NuRD. Molecular and Cellular Biology, vol.30, pp.5234-5244, 2010. ,
Multiple roles of class I HDACs in proliferation, differentiation, and development, Cell. Mol. Life Sci, vol.69, pp.2173-2187, 2012. ,
NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment, Cell Stem Cell, vol.10, pp.583-594, 2012. ,
The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex, Journal of Molecular and Cellular Cardiology, vol.44, pp.352-360, 2008. ,
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly, Mol. Cell, vol.15, pp.595-605, 2004. ,
Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes, Int. J. Dev. Biol, vol.53, pp.323-334, 2009. ,
The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7, Protein Sci, vol.25, pp.1472-1482, 2016. ,
Histone methylation by PRC2 is inhibited by active chromatin marks, Mol. Cell, vol.42, pp.330-341, 2011. ,
Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity, Journal of Biological Chemistry, vol.283, pp.11355-11363, 2008. ,
Two forms of the major antigenic protein of the dermatomyositis-specific Mi-2 autoantigen, Arthritis Rheum, vol.39, pp.1769-1771, 1996. ,
Regulating the Regulators: The Post-Translational Code of Class I HDAC1 and HDAC2, J Biomed Biotechnol, 2011. ,
A Role for Nuclear Actin in HDAC 1 and 2 Regulation, 2016. ,
Erasers of Histone Acetylation: The Histone Deacetylase Enzymes, Cold Spring Harb Perspect Biol, vol.6, 2014. ,
Rett syndrome and MeCP2: linking epigenetics and neuronal function, Am. J. Hum. Genet, vol.71, pp.1259-1272, 2002. ,
Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cells, Proc. Natl. Acad. Sci. U.S.A, vol.115, pp.6780-6785, 2018. ,
A chromatin remodelling complex involved in transcription and DNA processing, Nature, vol.406, pp.541-544, 2000. ,
Histone lysine demethylases: emerging roles in development, physiology and disease, Nat. Rev. Genet, vol.8, pp.829-833, 2007. ,
Regulation of LSD1 histone demethylase activity by its associated factors, Mol. Cell, vol.19, pp.857-864, 2005. ,
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1, Cell, vol.119, pp.941-953, 2004. ,
MBD3 localizes at promoters, gene bodies and enhancers of active genes, PLoS Genet, vol.9, 2013. ,
High-quality ChIP-seq analysis of MBD3 in human breast cancer cells, Genom Data, vol.7, pp.173-174, 2016. ,
DNA methylation: roles in mammalian development, Nat. Rev. Genet, vol.23, pp.204-220, 2013. ,
Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation, Science, vol.335, pp.709-712, 2012. ,
CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex, Mol. BioSyst, vol.6, pp.1700-1706, 2010. ,
ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage, Cell Reports, vol.17, pp.783-798, 2016. ,
Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes, J. Biol. Chem, vol.282, pp.30227-30238, 2007. ,
GraFix: stabilization of fragile macromolecular complexes for single particle cryo-EM, Meth. Enzymol, vol.481, pp.109-126, 2010. ,
NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines, EMBO J, vol.20, pp.4892-4900, 2001. ,
A gene atlas of the mouse and human protein-encoding transcriptomes, Proc. Natl. Acad. Sci. U.S.A, vol.101, pp.6062-6067, 2004. ,
The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases, Nat. Struct. Mol. Biol, vol.15, pp.469-476, 2008. ,
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1, Science, vol.324, pp.930-935, 2009. ,
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification, Cell, vol.146, pp.1016-1028, 2011. ,
Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1, J. Mol. Biol, vol.9, pp.27-38, 2001. ,
Covalent Modifications of Histone H3K9 Promote Binding of CHD3, Cell Reports, vol.21, pp.455-466, 2017. ,
Deleted in oral cancer-1 (doc-1), a novel oral tumor suppressor gene, FASEB J, vol.9, pp.1362-1370, 1995. ,
Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex, Nature, vol.395, pp.917-921, 1998. ,
Identification of a rapidly formed nonnucleosomal histone-DNA intermediate that is converted into chromatin by ACF, Mol. Cell, vol.43, pp.638-648, 2011. ,
Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex, Cell, vol.154, pp.1207-1219, 2013. ,
, Oncotarget, vol.6, pp.42892-42904, 2015.
Involvement of SUMO Modification in MBD1-and MCAF1-mediated Heterochromatin Formation, J. Biol. Chem, vol.281, pp.23180-23190, 2006. ,
Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex, EMBO reports, vol.8, pp.96-108, 1998. ,
Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4, Cell, vol.87, pp.95-104, 1996. ,
Volta phase plate data collection facilitates image processing and cryo-EM structure determination, Journal of Structural Biology, vol.202, pp.191-199, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-02409698
Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1, Mol. Cell. Biol, vol.20, pp.2108-2121, 2000. ,
A multiple subunit Mi-2 histone deacetylase from Xenopus laevis cofractionates with an associated Snf2 superfamily ATPase, Curr. Biol, vol.8, pp.843-846, 1998. ,
Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66?), J. Biol. Chem, vol.288, pp.3419-3427, 2013. ,
Opposing LSD1 complexes function in developmental gene activation and repression programmes, Nature, vol.446, pp.882-887, 2007. ,
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in, Breast Cancer. Cell, vol.138, pp.660-672, 2009. ,
Insights into the activation mechanism of class I HDAC complexes by inositol phosphates, Nature Communications, vol.7, p.11262, 2016. ,
The histone deacetylase-3 complex contains nuclear receptor corepressors, Proc. Natl. Acad. Sci. U.S.A, vol.97, pp.7202-7207, 2000. ,
Epigenetics in C. elegans: Facts and challenges, genesis, vol.49, pp.647-661, 2011. ,
URL : https://hal.archives-ouvertes.fr/ensl-00814756
Nucleosome mobilization catalysed by the yeast SWI/SNF complex, Nature, vol.400, pp.784-787, 1999. ,
Enhancer decommissioning by LSD1 during embryonic stem cell differentiation, Nature, vol.482, pp.221-225, 2012. ,
CHD4 and the NuRD complex directly control cardiac sarcomere formation, Proceedings of the National Academy of Sciences, vol.115, pp.6727-6732, 2018. ,
Risk Estimation for a Malignant Transformation of Oral Lesions by S100A7 and Doc-1 Gene Expression, Cancer Investigation, vol.29, pp.478-484, 2011. ,
N6-methyl-adenine: an epigenetic signal for DNA-protein interactions, Nat. Rev. Microbiol, vol.4, pp.183-192, 2006. ,
URL : https://hal.archives-ouvertes.fr/inserm-00390766
HDAC family: What are the cancer relevant targets?, Cancer Letters, vol.277, pp.8-21, 2009. ,
Emerging Molecular and Biological Functions of MBD2, a Reader of DNA Methylation, Frontiers in Genetics, vol.7, 2016. ,
Expression of cyclin-dependent kinase 2-associated protein 1 confers an independent prognosticator in nasopharyngeal carcinoma: a cohort study, J. Clin. Pathol, vol.65, pp.795-801, 2012. ,
TET-mediated active DNA demethylation: mechanism, function and beyond, Nat. Rev. Genet, vol.18, pp.517-534, 2017. ,
Dual functions of largest NURF subunit NURF301 in nucleosome sliding and transcription factor interactions, Mol. Cell, vol.8, pp.531-543, 2001. ,
DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants, Structure, vol.26, pp.85-95, 2018. ,
Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression, Genes Dev, vol.24, pp.455-469, 2010. ,
Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases, Mol. Cell, vol.6, pp.1195-1205, 2000. ,
Acetylation of Histone Deacetylase 1 Regulates NuRD Corepressor Complex Activity, J Biol Chem, vol.287, pp.40279-40291, 2012. ,
Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3, Proc. Natl. Acad. Sci. U.S.A, vol.93, pp.12845-12850, 1996. ,
LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer, J Mol Cell Biol, 2018. ,
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells, Cell, vol.147, pp.1498-1510, 2011. ,
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso, Mol. Cell, vol.12, pp.723-734, 2003. ,
CoREST is an integral component of the CoREST-human histone deacetylase complex, Proc. Natl. Acad. Sci. U.S.A, vol.98, pp.1454-1458, 2001. ,
Histone acetyltransferases: Rising ancient counterparts to protein kinases, Biopolymers, vol.99, pp.98-111, 2013. ,
Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1, Nat. Struct. Mol. Biol, vol.20, pp.29-35, 2013. ,
The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities, Cell, vol.95, pp.279-289, 1998. ,
Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2, Molecular Cell, vol.54, pp.879-886, 2014. ,
Recognition of methylated DNA through methyl-CpG binding domain proteins, Nucleic Acids Res, vol.40, pp.2747-2758, 2012. ,
Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase 1, Molecular and Cellular Biology, vol.26, pp.7913-7928, 2006. ,