, L'ensemble des 32 rats a été mis à mort 20 jours après le dernier jour d'acquisition (sans test de rappel)
, Les analyses effectuées sont des RT-qPCR pour évaluer l'expression des gènes immédiats cfos, zif268 et arc, ainsi que des Western blots pour évaluer les niveaux de la protéine c-Fos
, Les différents paramètres relevés en piscine de Morris ont fait l'objet d'un test ANOVA à un facteur (Chirurgie) à mesures répétées (Jours)
, Pour les analyses biochimiques, un test ANOVA à deux facteurs (Chirurgie, Groupe) a été fait, suivi d'un test post-hoc de Newman-Keuls lorsque cela était appoprié, p.5
, Au cours du jour d'« habituation », la distance parcourue pour atteindre la plate-forme diminue progressivement au cours des essais (F (3,36) = 34,2 ; p < 0,001), vol.113
, , 2016.
il aurait été intéressant d'effectuer un test de rappel sur un petit groupe de rats lésés, afin de voir si les deux jours d'entraînement supplémentaires leur auraient suffi pour rappeler l'emplacement de la plate-forme ,
Progression of activity and structural changes in the anterior cingulate cortex during remote memory formation, Neurobiol. Learn. Mem, vol.123, pp.67-71, 2015. ,
Recollective qualities modulate hippocampal activation during autobiographical memory retrieval, Hippocampus, vol.14, pp.752-762, 2004. ,
Mouse and rat BDNF gene structure and expression revisited, J. Neurosci. Res, vol.85, pp.525-535, 2007. ,
Environmental enrichment enhances systems-level consolidation of a spatial memory after lesions of the ventral midline thalamus, Neurobiol. Learn. Mem, vol.141, pp.108-123, 2017. ,
ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons, Learn. Mem. Cold Spring Harb. N, vol.11, pp.172-178, 2004. ,
Memory consolidation and the medial temporal lobe: a simple network model, Proc. Natl. Acad. Sci. U. S. A, vol.91, pp.7041-7045, 1994. ,
Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking, Cell, vol.154, pp.75-88, 2013. ,
Distribution of calretinin, calbindin-D28k, and parvalbumin in the rat thalamus, Brain Res. Bull, vol.33, pp.595-614, 1994. ,
MSK activation and physiological roles, Front. Biosci. J. Virtual Libr, vol.13, pp.5866-5879, 2008. ,
,
, Mitogen-and stress-activated protein kinase 1 mediates cAMP response elementbinding protein phosphorylation and activation by neurotrophins, J. Neurosci. Off. J. Soc. Neurosci, vol.24, pp.4324-4332
The MAPK cascade is required for mammalian associative learning, Nat. Neurosci, vol.1, pp.602-609, 1998. ,
The control of short-term memory, Sci. Am, vol.225, pp.82-90, 1971. ,
Nuclear calcium signalling in the regulation of brain function, Nat. Rev. Neurosci, vol.14, pp.593-608, 2013. ,
Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments, Proc. Natl. Acad. Sci. U. S. A, vol.108, pp.16813-16818, 2011. ,
Behavioral tagging is a general mechanism of long-term memory formation, Proc. Natl. Acad. Sci. U. S. A, vol.106, pp.14599-14604, 2009. ,
Synapse-specific stabilization of plasticity processes: the synaptic tagging and capture hypothesis revisited 10 years later, Neurosci. Biobehav. Rev, vol.32, pp.831-851, 2008. ,
Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory, 2011. ,
, Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol, vol.36, pp.1545-1556
Identification of the Ca2+/calmodulindependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor, J. Biol. Chem, vol.272, pp.32727-32730, 1997. ,
Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation, Science, vol.276, pp.2042-2045, 1997. ,
Temporal dynamics of Immediate Early Gene expression during cellular consolidation of spatial memory, Behav. Brain Res, 2017. ,
The time course of systems consolidation of spatial memory from recent to remote retention: A comparison of the Immediate Early Genes Zif268, c-Fos and Arc, Neurobiol. Learn. Mem, vol.128, pp.46-55, 2015. ,
Persistence of long-term memory storage requires a late protein synthesis-and BDNF-dependent phase in the hippocampus, Neuron, vol.53, pp.261-277, 2007. ,
BDNF is essential to promote persistence of long-term memory storage, Proc. Natl. Acad. Sci. U. S. A, vol.105, pp.2711-2716, 2008. ,
cAMP response element-binding protein is a primary hub of activity-driven neuronal gene expression, J. Neurosci. Off. J. Soc. Neurosci, vol.31, pp.18237-18250, 2011. ,
Modulation of taste-induced Elk-1 activation by identified neurotransmitter systems in the insular cortex of the behaving rat, Neurobiol. Learn. Mem, vol.79, pp.122-126, 2003. ,
, , 2014.
, Early remodeling of the neocortex upon episodic memory encoding, Proc. Natl. Acad. Sci. U. S. A, vol.111, pp.11852-11857
Thalamic excitation of hippocampal CA1 neurons: a comparison with the effects of CA3 stimulation, Neuroscience, vol.92, pp.15-26, 1999. ,
Elk-1 a transcription factor with multiple facets in the brain, Front. Neurosci, vol.5, p.35, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-02372608
Comparative dynamics of MAPK/ERK signalling components and immediate early genes in the hippocampus and amygdala following contextual fear conditioning and retrieval, Brain Struct. Funct, vol.219, pp.415-430, 2014. ,
Alternate 5' exons in the rat brainderived neurotrophic factor gene: differential patterns of expression across brain regions, Brain Res. Mol. Brain Res, vol.26, pp.225-232, 1994. ,
Neurotrophin-mediated rapid signaling in the central nervous system: mechanisms and functions, Physiol. Bethesda Md, vol.20, pp.70-78, 2005. ,
A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory, J. Neurosci. Off. J. Soc. Neurosci, vol.19, pp.3535-3544, 1999. ,
Cellular architecture of the nucleus reuniens thalami and its putative aspartatergic/glutamatergic projection to the hippocampus and medial septum in the rat, Eur. J. Neurosci, vol.16, pp.1227-1239, 2002. ,
Remodelling the extracellular matrix in development and disease, Nat. Rev. Mol. Cell Biol, vol.15, pp.786-801, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01952416
Time-dependent reorganization of brain circuitry underlying long-term memory storage, Nature, vol.400, pp.671-675, 1999. ,
Structural and molecular remodeling of dendritic spine substructures during long-term potentiation, Neuron, vol.82, pp.444-459, 2014. ,
Spatial memory consolidation is associated with induction of several lysine-acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus, Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol, vol.35, pp.2521-2537, 2010. ,
URL : https://hal.archives-ouvertes.fr/inserm-00516665
Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning, PloS One, vol.8, p.57816, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02106640
The immediate early gene arc/arg3.1: regulation, mechanisms, and function, J. Neurosci. Off. J. Soc. Neurosci, vol.28, pp.11760-11767, 2008. ,
Glutamate induces histone H3 phosphorylation but not acetylation in striatal neurons: role of mitogenand stress-activated kinase-1, J. Neurochem, vol.101, pp.697-708, 2007. ,
Role of the ERK/MSK1 signalling pathway in chromatin remodelling and brain responses to drugs of abuse, J. Neurochem, vol.108, pp.1323-1335, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00407701
Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning, J. Neurosci. Off. J. Soc. Neurosci, vol.30, pp.4590-4600, 2010. ,
Spatial memory, recognition memory, and the hippocampus, Proc. Natl. Acad. Sci. U. S. A, vol.101, pp.14515-14520, 2004. ,
Frontal cortex contributes to human memory formation, Nat. Neurosci, vol.2, pp.311-314, 1999. ,
Learning-associated activation of nuclear MAPK, CREB and Elk-1, along with Fos production, in the rat hippocampus after a one-trial avoidance learning: abolition by NMDA receptor blockade, Brain Res. Mol. Brain Res, vol.76, pp.36-46, 2000. ,
The phosphoinositide 3-kinase pathway, Science, vol.296, pp.1655-1657, 2002. ,
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol, Mol. Biol. Rev. MMBR, vol.75, pp.50-83, 2011. ,
Distinct epigenetic and gene expression changes in rat hippocampal neurons after Morris water maze training, Front. Behav. Neurosci, vol.9, p.156, 2015. ,
Memory-specific temporal profiles of gene expression in the hippocampus, Proc. Natl. Acad. Sci. U. S. A, vol.99, pp.16279-16284, 2002. ,
A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice, J. Neurosci. Off. J. Soc. Neurosci, vol.33, pp.10698-10712, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02106635
BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae, Mol. Cell. Neurosci, vol.37, pp.11-19, 2008. ,
, , 2010.
, Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear, Proc. Natl. Acad. Sci. U. S. A, vol.107, pp.2675-2680
The ventral midline thalamus contributes to strategy shifting in a memory task requiring both prefrontal cortical and hippocampal functions, J. Neurosci. Off. J. Soc. Neurosci, vol.33, pp.8772-8783, 2013. ,
Dorsal hippocampus and medial prefrontal cortex each contribute to the retrieval of a recent spatial memory in rats, Brain Struct. Funct, vol.221, pp.91-102, 2014. ,
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking, Neuron, vol.52, pp.445-459, 2006. ,
The nuclear kinase mitogen-and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation, J. Neurosci. Off. J. Soc. Neurosci, vol.27, pp.12732-12742, 2007. ,
Intrahippocampal administration of BDNF in adult rats affects short-term behavioral plasticity in the Morris water maze and performance in the elevated plus-maze, Hippocampus, vol.14, pp.802-807, 2004. ,
Hippocampus and remote spatial memory in rats, Hippocampus, vol.15, pp.260-272, 2005. ,
Receptor trafficking and synaptic plasticity, Nat. Rev. Neurosci, vol.5, pp.952-962, 2004. ,
Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears, J. Neurosci. Off. J. Soc. Neurosci, vol.27, pp.840-844, 2007. ,
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2, Nature, vol.436, pp.1166-1173, 2005. ,
eIF2alpha phosphorylation bidirectionally regulates the switch from short-to long-term synaptic plasticity and memory, Cell, vol.129, pp.195-206, 2007. ,
Lysophosphatidic acid induces early growth response gene 1 expression in vascular smooth muscle cells: CRE and SRE mediate the transcription, Arterioscler. Thromb. Vasc. Biol, vol.26, pp.1029-1035, 2006. ,
General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus, Anesthesiology, vol.124, pp.1311-1327, 2016. ,
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates, Neurosci. Biobehav. Rev, vol.28, pp.771-784, 2004. ,
The Kinase Function of MSK1 Regulates BDNF Signaling to CREB and Basal Synaptic Transmission, But Is Not Required for Hippocampal Long-Term Potentiation or Spatial Memory, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02351252
The MAPK/ERK cascade targets both Elk-1 and cAMP response element-binding protein to control long-term potentiation-dependent gene expression in the dentate gyrus in vivo, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.4563-4572, 2000. ,
URL : https://hal.archives-ouvertes.fr/hal-02372697
Effect of reversible inactivation of the reuniens nucleus on spatial learning and memory in rats using Morris water maze task, Behav. Brain Res, vol.198, pp.130-135, 2009. ,
Effect of reversible inactivation of reuniens nucleus on memory processing in passive avoidance task, Behav. Brain Res, vol.221, pp.1-6, 2011. ,
The elongation, termination, and recycling phases of translation in eukaryotes, Cold Spring Harb. Perspect. Biol, vol.4, 2012. ,
Applications of the Morris water maze in the study of learning and memory, Brain Res. Brain Res. Rev, vol.36, pp.60-90, 2001. ,
Excitatory actions of the ventral midline thalamus (rhomboid/reuniens) on the medial prefrontal cortex in the rat, Synap. N. Y. N, vol.60, pp.45-55, 2006. ,
Hippocampal long-term depression is facilitated by the acquisition and updating of memory of spatial auditory content and requires mGlu5 activation, Neuropharmacology, vol.115, pp.30-41, 2017. ,
Projections from the nucleus reuniens thalami to the entorhinal cortex, hippocampal field CA1, and the subiculum in the rat arise from different populations of neurons, J. Comp. Neurol, vol.364, pp.637-650, 1996. ,
Nucleus reuniens thalami modulates activity in hippocampal field CA1 through excitatory and inhibitory mechanisms, J. Neurosci. Off. J. Soc. Neurosci, vol.17, pp.5640-5650, 1997. ,
Delta frequency optogenetic stimulation of the thalamic nucleus reuniens is sufficient to produce working memory deficits: relevance to schizophrenia, Biol. Psychiatry, vol.77, pp.1098-1107, 2015. ,
Role of Reuniens Nucleus Projections to the Medial Prefrontal Cortex and to the Hippocampal Pyramidal CA1 Area in Associative Learning, PLoS ONE, vol.6, 2011. ,
A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation, J. Biol. Chem, vol.272, pp.19103-19106, 1997. ,
Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family, Neuron, vol.5, pp.511-526, 1990. ,
Are the dorsal and ventral hippocampus functionally distinct structures?, Neuron, vol.65, pp.7-19, 2010. ,
Differential expression of immediate early genes Zif268 and c-Fos in the hippocampus and prefrontal cortex following spatial learning and glutamate receptor antagonism, Behav. Brain Res, vol.307, pp.194-198, 2016. ,
Interstitial collagen catabolism, J. Biol. Chem, vol.288, pp.8785-8793, 2013. ,
Targeting bromodomains: epigenetic readers of lysine acetylation, Nat. Rev. Drug Discov, vol.13, pp.337-356, 2014. ,
Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS, J. Neurosci. Off. J. Soc. Neurosci, vol.23, pp.9116-9122, 2003. ,
The organization of recent and remote memories, Nat. Rev. Neurosci, vol.6, pp.119-130, 2005. ,
Alpha-CaMKIIdependent plasticity in the cortex is required for permanent memory, Nature, vol.411, pp.309-313, 2001. ,
The involvement of the anterior cingulate cortex in remote contextual fear memory, Science, vol.304, pp.881-883, 2004. ,
Neuromodulated Spike-Timing-Dependent Plasticity, and Theory of Three-Factor Learning Rules, Front. Neural Circuits, vol.9, p.85, 2015. ,
Synaptic tagging and long-term potentiation, Nature, vol.385, pp.533-536, 1997. ,
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons, Science, vol.260, pp.1661-1664, 1993. ,
Developmental and mature expression of full-length and truncated TrkB receptors in the rat forebrain, J. Comp. Neurol, vol.374, pp.21-40, 1996. ,
Brainderived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin, J. Neurosci. Off. J. Soc. Neurosci, vol.24, pp.10741-10749, 2004. ,
Metabotropic glutamate receptormediated long-term depression: molecular mechanisms, Pharmacol. Rev, vol.61, pp.395-412, 2009. ,
Protein kinase C and ERK involvement in dendritic spine plasticity in cultured rodent hippocampal neurons, Eur. J. Neurosci, vol.17, pp.2529-2539, 2003. ,
The optogenetic revolution in memory research, Trends Neurosci, vol.37, pp.511-522, 2014. ,
Aerobic glycolysis in the human brain is associated with development and neotenous gene expression, Cell Metab, vol.19, pp.49-57, 2014. ,
Histone acetylation: molecular mnemonics on the chromatin, Nat. Rev. Neurosci, vol.14, pp.97-111, 2013. ,
Epigenetic regulation of gene expression in physiological and pathological brain processes, Physiol. Rev, vol.91, pp.603-649, 2011. ,
Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation, Nat. Commun, vol.3, p.991, 2012. ,
Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.3993-4001, 2000. ,
Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268, J. Neurosci. Off. J. Soc. Neurosci, vol.21, pp.5089-5098, 2001. ,
HDAC inhibition modulates hippocampus-dependent long-term memory for object location in a CBP-dependent manner, Learn. Mem. Cold Spring Harb. N, vol.18, pp.71-79, 2011. ,
Microstructure of a spatial map in the entorhinal cortex, Nature, vol.436, pp.801-806, 2005. ,
DNA methylation changes in plasticity genes accompany the formation and maintenance of memory, Nat. Neurosci, vol.19, pp.102-110, 2016. ,
Rapid and selective induction of BDNF expression in the hippocampus during contextual learning, Nat. Neurosci, vol.3, pp.533-535, 2000. ,
Transient inactivation of the thalamic nucleus reuniens and rhomboid nucleus produces deficits of a working-memory dependent tactile-visual conditional discrimination task, Behav. Neurosci, vol.127, pp.860-866, 2013. ,
Ventral Midline Thalamus Is Critical for Hippocampal-Prefrontal Synchrony and Spatial Working Memory, J. Neurosci. Off. J. Soc. Neurosci, vol.36, pp.8372-8389, 2016. ,
Selective hippocampal damage in rhesus monkeys impairs spatial memory in an open-field test, Hippocampus, vol.14, pp.808-818, 2004. ,
The Secretory Pathway From History to the State of the Art, Fusion of Biological Membranes and Related Problems, pp.1-38, 2002. ,
A role of Fos expression in the CA3 region of the hippocampus in spatial memory formation in rats, Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol, vol.26, pp.259-268, 2002. ,
Extracellular signal-regulated kinase activity in the entorhinal cortex is necessary for long-term spatial memory, Learn. Mem. Cold Spring Harb. N, vol.9, pp.156-166, 2002. ,
Lesions of reuniens and rhomboid thalamic nuclei impair radial maze win-shift performance, Hippocampus, vol.21, pp.815-826, 2011. ,
Inactivation of ventral midline thalamus produces selective spatial delayed conditional discrimination impairment in the rat, Hippocampus, vol.22, pp.853-860, 2012. ,
Hippocampal pathway to the amygdala and stress ulcer development, Brain Res. Bull, vol.25, pp.691-695, 1990. ,
The connections of the nucleus reuniens thalami: evidence for a direct thalamo-hippocampal pathway in the rat, J. Comp. Neurol, vol.177, pp.589-610, 1978. ,
Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking, Annu. Rev. Physiol, vol.78, pp.351-365, 2016. ,
Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat, Brain Struct. Funct, vol.212, pp.149-179, 2007. ,
Collateral projections from nucleus reuniens of thalamus to hippocampus and medial prefrontal cortex in the rat: a single and double retrograde fluorescent labeling study, Brain Struct. Funct, vol.217, pp.191-209, 2012. ,
A temporary local energy pool coupled to neuronal activity: fluctuations of extracellular lactate levels in rat brain monitored with rapid-response enzyme-based sensor, J. Neurochem, vol.69, pp.1484-1490, 1997. ,
Differential regulation of AMPA receptor trafficking by neurabin-targeted synaptic protein phosphatase-1 in synaptic transmission and long-term depression in hippocampus, J. Neurosci. Off. J. Soc. Neurosci, vol.27, pp.4674-4686, 2007. ,
Neurotrophins: roles in neuronal development and function, Annu. Rev. Neurosci, vol.24, pp.677-736, 2001. ,
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists, Nucleic Acids Res, vol.35, pp.169-175, 2007. ,
Dissociating the roles of dorsal and ventral CA1 for the temporal processing of spatial locations, visual objects, and odors, Behav. Neurosci, vol.122, pp.643-650, 2008. ,
MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins, FEBS Open Bio, vol.7, pp.821-834, 2017. ,
A prefrontalthalamo-hippocampal circuit for goal-directed spatial navigation, Nature, vol.522, pp.50-55, 2015. ,
The mechanism of eukaryotic translation initiation and principles of its regulation, Nat. Rev. Mol. Cell Biol, vol.11, pp.113-127, 2010. ,
Termination and post-termination events in eukaryotic translation, Adv. Protein Chem. Struct. Biol, vol.86, pp.45-93, 2012. ,
Genomic profiling of the neuronal target genes of the plasticity-related transcription factor --Zif268, J. Neurochem, vol.95, pp.796-810, 2005. ,
, , 2014.
Evidence for spatially-responsive neurons in the rostral thalamus, Front. Behav. Neurosci, vol.9, p.256, 2015. ,
A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories, Nat. Neurosci, vol.4, pp.289-296, 2001. ,
URL : https://hal.archives-ouvertes.fr/hal-02537928
Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartmentspecific translation control, J. Neurochem, vol.99, pp.1328-1337, 2006. ,
Temporally-specific retrograde amnesia in two cases of discrete bilateral hippocampal pathology, Hippocampus, vol.9, pp.247-254, 1999. ,
MSK1 regulates environmental enrichment-induced hippocampal plasticity and cognitive enhancement, Learn. Mem. Cold Spring Harb. N, vol.19, pp.550-560, 2012. ,
AP-1 function and regulation, Curr. Opin. Cell Biol, vol.9, pp.240-246, 1997. ,
, , 1996.
, Immunohistochemical localization of brain-derived neurotrophic factor in adult rat brain, Neuroscience, vol.74, pp.1209-1226
Requirement for mitogen-activated protein kinase in cerebellar long term depression, J. Biol. Chem, vol.274, pp.13498-13502, 1999. ,
Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons, Proc. Natl. Acad. Sci. U. S. A, vol.106, pp.316-321, 2009. ,
Function of alternative splicing, Gene, vol.514, pp.1-30, 2013. ,
Translational control by MAPK signaling in long-term synaptic plasticity and memory, Cell, vol.116, pp.467-479, 2004. ,
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family, Genome Biol, vol.16, p.113, 2015. ,
Synaptic Signaling in Learning and Memory, Cold Spring Harb. Perspect. Biol, vol.8, 2013. ,
Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance?, Behav. Neurosci, vol.112, pp.1012-1019, 1998. ,
Dual-specificity MAP kinase phosphatases (MKPs) and cancer, Cancer Metastasis Rev, vol.27, pp.253-261, 2008. ,
Reduced fear expression after lesions of the ventral hippocampus, Proc. Natl. Acad. Sci. U. S. A, vol.99, pp.10825-10830, 2002. ,
Hippocampal-dependent spatial memory functions might be lateralized in rats: An approach combining gene expression profiling and reversible inactivation, Hippocampus, vol.19, pp.800-816, 2009. ,
Intracellular domains of NMDA receptor subtypes are determinants for long-term potentiation induction, J. Neurosci. Off. J. Soc. Neurosci, vol.23, pp.10791-10799, 2003. ,
Tissue-specific and neural activity-regulated expression of human BDNF gene in BAC transgenic mice, BMC Neurosci, vol.10, p.68, 2009. ,
, , 1995.
, Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor, Proc. Natl. Acad. Sci. U. S. A, vol.92, pp.8856-8860
A role for BDNF in the latephase of hippocampal long-term potentiation, Neuropharmacology, vol.37, pp.553-559, 1998. ,
Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes, Nucleic Acids Res, vol.9, pp.5233-5252, 1981. ,
Brainstem projections to midline and intralaminar thalamic nuclei of the rat, J. Comp. Neurol, vol.448, pp.53-101, 2002. ,
Nuclear RNA-seq of single neurons reveals molecular signatures of activation, Nat. Commun, vol.7, p.11022, 2016. ,
A TAT-DEF-Elk-1 peptide regulates the cytonuclear trafficking of Elk-1 and controls cytoskeleton dynamics, J. Neurosci. Off. J. Soc. Neurosci, vol.27, pp.14448-14458, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00258855
Hippocampal lesion prevents spatial relational learning in adult macaque monkeys, J. Neurosci. Off. J. Soc. Neurosci, vol.26, pp.4546-4558, 2006. ,
Inactivation of the nucleus reuniens/rhomboid causes a delay-dependent impairment of spatial working memory, Neurobiol. Learn. Mem, vol.125, pp.163-167, 2015. ,
BDNF-induced local protein synthesis and synaptic plasticity, Neuropharmacology, vol.76, pp.639-656, 2014. ,
Regulation of hippocampal synaptic plasticity by BDNF, Brain Res, vol.1621, pp.82-101, 2015. ,
Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization, J. Neurosci. Off. J. Soc. Neurosci, vol.24, pp.3879-3889, 2004. ,
Early tagging of cortical networks is required for the formation of enduring associative memory, Science, vol.331, pp.924-928, 2011. ,
Neurotrophin secretion: current facts and future prospects, Prog. Neurobiol, vol.69, pp.341-374, 2003. ,
Regulation of histone acetylation during memory formation in the hippocampus, J. Biol. Chem, vol.279, pp.40545-40559, 2004. ,
Boundary vector cells in the subiculum of the hippocampal formation, J. Neurosci. Off. J. Soc. Neurosci, vol.29, pp.9771-9777, 2009. ,
Unilateral lesion of dorsal hippocampus in adult rats impairs contralateral long-term potentiation in vivo and spatial memory in the early postoperative phase, Behav. Brain Res, vol.230, pp.428-432, 2012. ,
ATPase/helicase activities of p68 RNA helicase are required for pre-mRNA splicing but not for assembly of the spliceosome, Mol. Cell. Biol, vol.25, pp.7484-7493, 2005. ,
Long-term depression activates transcription of immediate early transcription factor genes: involvement of serum response factor/Elk-1, Eur. J. Neurosci, vol.24, pp.555-563, 2006. ,
Dead-box proteins: a family affair-active and passive players in RNPremodeling, Nucleic Acids Res, vol.34, pp.4168-4180, 2006. ,
Lesions of the ventral midline thalamus produce deficits in reversal learning and attention on an odor texture set shifting task, Brain Res, vol.1649, pp.110-122, 2016. ,
Learning deficit in BDNF mutant mice, Eur. J. Neurosci, vol.9, pp.2581-2587, 1997. ,
Glutamatergic synapses are structurally and biochemically complex because of multiple plasticity processes: long-term potentiation, long-term depression, short-term potentiation and scaling, Philos. Trans. R. Soc. Lond. B. Biol. Sci, vol.372, 2017. ,
A neoHebbian framework for episodic memory; role of dopamine-dependent late LTP, Trends Neurosci, vol.34, pp.536-547, 2011. ,
Time-dependent expression of Arc and zif268 after acquisition of fear conditioning, Neural Plast, p.139891, 2010. ,
Environmental cue saliency influences the vividness of a remote spatial memory in rats, Neurobiol. Learn. Mem, vol.90, pp.285-289, 2008. ,
Context-dependent modulation of hippocampal and cortical recruitment during remote spatial memory retrieval, Hippocampus, vol.22, pp.827-841, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01159975
The ventral midline thalamus (reuniens and rhomboid nuclei) contributes to the persistence of spatial memory in rats, J. Neurosci. Off. J. Soc. Neurosci, vol.32, pp.9947-9959, 2012. ,
Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites, Neuron, vol.14, pp.433-445, 1995. ,
Mechanisms of specificity in neuronal activity-regulated gene transcription, Prog. Neurobiol, vol.94, pp.259-295, 2011. ,
Lateral asymmetry in the hippocampal response to the remoteness of autobiographical memories, J. Neurosci. Off. J. Soc. Neurosci, vol.23, pp.5302-5307, 2003. ,
Recalling routes around london: activation of the right hippocampus in taxi drivers, J. Neurosci. Off. J. Soc. Neurosci, vol.17, pp.7103-7110, 1997. ,
Knowing where and getting there: a human navigation network, Science, vol.280, pp.921-924, 1998. ,
AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis, Neuron, vol.64, pp.381-390, 2009. ,
Requirement of translation but not transcription for the maintenance of long-term depression in the CA1 region of freely moving rats, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.8572-8576, 2000. ,
, , 2011.
, Coordinated sumoylation and ubiquitination modulate EGF induced EGR1 expression and stability, PloS One, vol.6, 25676.
Selective effects of pentobarbital and halothane on c-fos and jun-B gene expression in rat brain, Anesthesiology, vol.77, pp.365-371, 1992. ,
Simple memory: a theory for archicortex, Philos. Trans. R. Soc. Lond. B. Biol. Sci, vol.262, pp.23-81, 1971. ,
Retrograde amnesia: neither partial nor complete hippocampal lesions in rats result in preferential sparing of remote spatial memory, even after reminding, Neuropsychologia, vol.43, pp.609-624, 2005. ,
A day in the life of the spliceosome, Nat. Rev. Mol. Cell Biol, vol.15, pp.108-121, 2014. ,
The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction, Glia, vol.58, pp.1094-1103, 2010. ,
Differential activity-dependent secretion of brain-derived neurotrophic factor from axon and dendrite, J. Neurosci. Off. J. Soc. Neurosci, vol.29, pp.14185-14198, 2009. ,
Sites of neocortical reorganization critical for remote spatial memory, Science, vol.305, pp.96-99, 2004. ,
Neuroplasticity mediated by altered gene expression, Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol, vol.33, pp.3-17, 2008. ,
Afferent projections to nucleus reuniens of the thalamus, J. Comp. Neurol, vol.480, pp.115-142, 2004. ,
Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo, J. Neurosci. Off. J. Soc. Neurosci, vol.22, pp.7453-7461, 2002. ,
Balance and stability of synaptic structures during synaptic plasticity, Neuron, vol.82, pp.430-443, 2014. ,
The magical number seven, plus or minus two: some limits on our capacity for processing information, Psychol. Rev, vol.101, pp.343-352, 1956. ,
Mechanism of TrkB-mediated hippocampal long-term potentiation, Neuron, vol.36, pp.121-137, 2002. ,
Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.7116-7121, 2000. ,
The regulation of exon-specific brain-derived neurotrophic factor mRNA expression by protein kinase C in rat cultured dorsal root ganglion neurons, Brain Res, vol.1509, pp.20-31, 2013. ,
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5, Nature, vol.319, pp.774-776, 1986. ,
Distributed encoding and retrieval of spatial memory in the hippocampus, J. Neurosci. Off. J. Soc. Neurosci, vol.18, pp.7535-7542, 1998. ,
Spatial learning impairment parallels the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions, J. Neurosci. Off. J. Soc. Neurosci, vol.13, pp.3916-3925, 1993. ,
Spatial learning with a minislab in the dorsal hippocampus, Proc. Natl. Acad. Sci. U. S. A, vol.92, pp.9697-9701, 1995. ,
Place cells, grid cells, and memory, Cold Spring Harb. Perspect. Biol, vol.7, 2015. ,
Biosynthesis and post-translational processing of the precursor to brain-derived neurotrophic factor, J. Biol. Chem, vol.276, pp.12660-12666, 2001. ,
Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats, Brain Res, vol.835, pp.259-265, 1999. ,
An essential role for protein phosphatases in hippocampal long-term depression, Science, vol.261, pp.1051-1055, 1993. ,
Engineering a memory with LTD and LTP, Nature, vol.511, pp.348-352, 2014. ,
Memory consolidation, retrograde amnesia and the hippocampal complex, Curr. Opin. Neurobiol, vol.7, pp.217-227, 1997. ,
Control of extracellular cleavage of ProBDNF by high frequency neuronal activity, Proc. Natl. Acad. Sci. U. S. A, vol.106, pp.1267-1272, 2009. ,
Lactate produced by glycogenolysis in astrocytes regulates memory processing, PloS One, vol.6, 2011. ,
Recent insights into regulation of transcription by RNA polymerase III and the cellular functions of its transcripts, Biol. Chem, vol.392, pp.395-404, 2011. ,
BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment, Hippocampus, vol.25, pp.1-15, 2015. ,
Selective spatial memory impairment after right unilateral temporal lobectomy, Neuropsychologia, vol.36, pp.837-848, 1998. ,
The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat, Brain Res, vol.34, pp.171-175, 1971. ,
Regulation and function of immediate-early genes in the brain: beyond neuronal activity markers, Neurosci. Res, vol.69, pp.175-186, 2011. ,
Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKII?, Cell, vol.149, pp.886-898, 2012. ,
Two distinct forms of long-term depression coexist in CA1 hippocampal pyramidal cells, Neuron, vol.18, pp.969-982, 1997. ,
URL : https://hal.archives-ouvertes.fr/inserm-00000073
Mazes, maps, and memory, Am. Psychol, vol.34, pp.583-596, 1979. ,
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases, Oncogene, vol.26, pp.3203-3213, 2007. ,
Medial prefrontal cortex lesions impair decision-making on a rodent gambling task: reversal by D1 receptor antagonist administration, Behav. Brain Res, vol.243, pp.247-254, 2013. ,
Allocentric spatial memory activation of the hippocampal formation measured with fMRI, Neuropsychology, vol.18, pp.450-461, 2004. ,
Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo, Mol. Cell. Neurosci, vol.28, pp.556-570, 2005. ,
AMPA receptors are exocytosed in stimulated spines and adjacent dendrites in a Ras-ERK-dependent manner during long-term potentiation, Proc. Natl. Acad. Sci. U. S. A, vol.107, pp.15951-15956, 2010. ,
The Rat Brain in Stereotaxic Coordinates, 2007. ,
Arc regulates spine morphology and maintains network stability in vivo, Proc. Natl. Acad. Sci. U. S. A, vol.107, pp.18173-18178, 2010. ,
Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization, Proc. Natl. Acad. Sci. U. S. A, vol.91, pp.10625-10629, 1994. ,
Zif268/Egr1 gain of function facilitates hippocampal synaptic plasticity and long-term spatial recognition memory, Philos. Trans. R. Soc. Lond. B. Biol. Sci, vol.369, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-02425773
Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories, Neuron, vol.52, pp.437-444, 2006. ,
Contextual fear conditioning induces differential alternative splicing, Neurobiol. Learn. Mem, vol.134, pp.221-235, 2016. ,
Short-term temporal changes in free recall, Q. J. Exp. Psychol, vol.17, pp.132-138, 1965. ,
, , 2004.
, Dissociation of function between the dorsal and the ventral hippocampus in spatial learning abilities of the rat: a within-subject, within-task comparison of reference and working spatial memory, Eur. J. Neurosci, vol.19, pp.705-712
Lesions of the thalamic reuniens cause impulsive but not compulsive responses, Brain Struct. Funct, vol.218, pp.85-96, 2013. ,
Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation, Proc. Natl. Acad. Sci. U. S. A, vol.88, pp.5829-5831, 1991. ,
Identification of ciselements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene, J. Neurosci. Off. J. Soc. Neurosci, vol.31, pp.3295-3308, 2011. ,
The contribution of the rat prelimbic-infralimbic areas to different forms of task switching, Behav. Neurosci, vol.117, pp.1054-1065, 2003. ,
Projections from neocortex mediate topdown control of memory retrieval, Nature, vol.526, pp.653-659, 2015. ,
Long lasting protein synthesis-and activitydependent spine shrinkage and elimination after synaptic depression, PloS One, vol.8, 2013. ,
Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning, Learn. Mem. Cold Spring Harb. N, vol.11, pp.727-731, 2004. ,
Making memories last: the synaptic tagging and capture hypothesis, Nat. Rev. Neurosci, vol.12, pp.17-30, 2011. ,
The formation of recent and remote memory is associated with time-dependent formation of dendritic spines in the hippocampus and anterior cingulate cortex, J. Neurosci. Off. J. Soc. Neurosci, vol.29, pp.8206-8214, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-01161790
Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus, J. Neurosci. Off. J. Soc. Neurosci, vol.27, pp.3017-3029, 2007. ,
Guilt by association: PAX3-FOXO1 regulates gene expression through selective destabilization of the EGR1 transcription factor, Cell Cycle Georget. Tex, vol.7, pp.837-841, 2008. ,
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus, Proc. Natl. Acad. Sci. U. S. A, vol.102, pp.7362-7367, 2005. ,
Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300, Oncogene, vol.22, pp.151-156, 2003. ,
DREADDs for Neuroscientists, Neuron, vol.89, pp.683-694, 2016. ,
Differential Expression and Regulation of Brain-Derived Neurotrophic Factor (BDNF) mRNA Isoforms in Brain Cells from Mecp2(308/y) Mouse Model, J. Mol. Neurosci. MN, vol.56, pp.758-767, 2015. ,
Phosphorylation of hippocampal Erk-1/2, Elk-1, and p90-Rsk-1 during contextual fear conditioning: interactions between Erk-1/2 and Elk-1, Mol. Cell. Neurosci, vol.21, pp.463-476, 2002. ,
, , 2006.
, Spatiotemporal regulation of c-Fos by ERK5 and the E3 ubiquitin ligase UBR1, and its biological role, Mol. Cell, vol.24, pp.63-75
Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.8177-8187, 2000. ,
Cell signaling by receptor tyrosine kinases, Cell, vol.103, pp.211-225, 2000. ,
Anatomy of the hippocampal formation, Front. Neurol. Neurosci, vol.34, pp.6-17, 2014. ,
The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications, J. Leukoc. Biol, vol.101, pp.183-192, 2016. ,
Loss of recent memory after bilateral hippocampal lesions, J. Neurol. Neurosurg. Psychiatry, vol.20, pp.11-21, 1957. ,
A necessity for MAP kinase activation in mammalian spatial learning, Learn. Mem. Cold Spring Harb. N, vol.6, pp.478-490, 1999. ,
Mice lacking the ERK1 isoform of MAP kinase are unimpaired in emotional learning, Learn. Mem. Cold Spring Harb. N, vol.8, pp.11-19, 2001. ,
, , 2003.
, A role for ERK MAP kinase in physiologic temporal integration in hippocampal area CA1, Learn. Mem. Cold Spring Harb. N, vol.10, pp.26-39
Neuronal MEK is important for normal fear conditioning in mice, J. Neurosci. Res, vol.75, pp.760-770, 2004. ,
The transcription cycle in eukaryotes: From productive initiation to RNA polymerase II recycling, Biochim. Biophys. Acta BBA -Gene Regul. Mech, vol.1819, pp.391-400, 2012. ,
Role of DUSP1/MKP1 in tumorigenesis, tumor progression and therapy, Cancer Med, vol.5, pp.2061-2068, 2016. ,
Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences, Mol. Cell. Biol, vol.8, pp.2787-2796, 1988. ,
Identification of a signaling pathway involved in calcium regulation of BDNF expression, Neuron, vol.20, pp.727-740, 1998. ,
Left-right dissociation of hippocampal memory processes in mice, Proc. Natl. Acad. Sci. U. S. A, vol.111, pp.15238-15243, 2014. ,
Deficient hippocampal longterm potentiation in alpha-calcium-calmodulin kinase II mutant mice, Science, vol.257, pp.201-206, 1992. ,
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice, Science, vol.257, pp.206-211, 1992. ,
Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons, Neuron, vol.45, pp.765-779, 2005. ,
Representation of geometric borders in the entorhinal cortex, Science, vol.322, pp.1865-1868, 2008. ,
Brain-derived neurotrophic factor and control of synaptic consolidation in the adult brain, Biochem. Soc. Trans, vol.34, pp.600-604, 2006. ,
Encoding novel face-name associations: a functional MRI study, Hum. Brain Mapp, vol.14, pp.129-139, 2001. ,
Retrograde amnesia: temporal gradient in very long term memory following electroconvulsive therapy, Science, vol.187, pp.77-79, 1975. ,
Degradation of the proto-oncogene product c-Fos by the ubiquitin proteolytic system in vivo and in vitro: identification and characterization of the conjugating enzymes, Mol. Cell. Biol, vol.15, pp.7106-7116, 1995. ,
Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation, Neuron, vol.30, pp.227-240, 2001. ,
Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites, Neuron, vol.21, pp.741-751, 1998. ,
SoxE function in vertebrate nervous system development, Int. J. Biochem. Cell Biol, vol.42, pp.437-440, 2010. ,
The Sox9 transcription factor determines glial fate choice in the developing spinal cord, Genes Dev, vol.17, pp.1677-1689, 2003. ,
Regulation and Function of the RasGRP Family of Ras Activators in Blood Cells, Genes Cancer, vol.2, pp.320-334, 2011. ,
Functional organization of the hippocampal longitudinal axis, Nat. Rev. Neurosci, vol.15, pp.655-669, 2014. ,
Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis, J. Recept. Signal Transduct. Res, vol.35, pp.600-604, 2015. ,
Astrocyte-neuron lactate transport is required for long-term memory formation, Cell, vol.144, pp.810-823, 2011. ,
Mitogen-activated protein kinases in synaptic plasticity and memory, Curr. Opin. Neurobiol, vol.14, pp.311-317, 2004. ,
The STRING database in 2017: qualitycontrolled protein-protein association networks, made broadly accessible, Nucleic Acids Res, vol.45, pp.362-368, 2017. ,
Time-dependent reorganization of the brain components underlying memory retention in trace eyeblink conditioning, J. Neurosci. Off. J. Soc. Neurosci, vol.23, pp.9897-9905, 2003. ,
Brain-derived neurotrophic factor enhances the basal rate of protein synthesis by increasing active eukaryotic elongation factor 2 levels and promoting translation elongation in cortical neurons, J. Biol. Chem, vol.284, pp.26340-26348, 2009. ,
Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism, Neuron, vol.20, pp.709-726, 1998. ,
Head-direction cells recorded from the postsubiculum in freely moving rats. I. Description and quantitative analysis, J. Neurosci. Off. J. Soc. Neurosci, vol.10, pp.420-435, 1990. ,
Involvement of the anterior cingulate cortex in the expression of remote spatial memory, J. Neurosci. Off. J. Soc. Neurosci, vol.26, pp.7555-7564, 2006. ,
Long-term depression in the adult hippocampus in vivo involves activation of extracellular signalregulated kinase and phosphorylation of Elk-1, J. Neurosci. Off. J. Soc. Neurosci, vol.22, pp.2054-2062, 2002. ,
MAPK cascade signalling and synaptic plasticity, Nat. Rev. Neurosci, vol.5, pp.173-183, 2004. ,
Multiple promoters direct tissue-specific expression of the rat BDNF gene, Neuron, vol.10, pp.475-489, 1993. ,
Identification of brain-derived neurotrophic factor promoter regions mediating tissuespecific, axotomy-, and neuronal activity-induced expression in transgenic mice, J. Cell Biol, vol.128, pp.185-199, 1995. ,
High field structural MRI reveals specific episodic memory correlates in the subfields of the hippocampus, Neuropsychologia, vol.53, pp.233-245, 2014. ,
Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors, Cell, vol.46, pp.567-574, 1986. ,
Biphasic ERK1/2 activation in both the hippocampus and amygdala may reveal a system consolidation of contextual fear memory, Neurobiol. Learn. Mem, vol.88, pp.424-434, 2007. ,
Endocytosis controls glutamate-induced nuclear accumulation of ERK, Mol. Cell. Neurosci, vol.41, pp.325-336, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-02372619
, Organization of memory, 1972.
Serum-and glucocorticoid-inducible kinase 1 enhances zif268 expression through the mediation of SRF and CREB1 associated with spatial memory formation, J. Neurochem, vol.105, pp.820-832, 2008. ,
Transient inactivation of the medial prefrontal cortex impairs performance on a working memory-dependent conditional discrimination task, Behav. Neurosci, vol.128, pp.639-643, 2014. ,
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum, Proc. Natl. Acad. Sci. U. S. A, vol.102, pp.491-496, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00084826
The intralaminar and midline nuclei of the thalamus. Anatomical and functional evidence for participation in processes of arousal and awareness, Brain Res. Brain Res. Rev, vol.39, pp.107-140, 2002. ,
Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices, Mol. Cell. Biol, vol.19, pp.136-146, 1999. ,
URL : https://hal.archives-ouvertes.fr/hal-02372736
Fos imaging reveals differential patterns of hippocampal and parahippocampal subfield activation in rats in response to different spatial memory tests, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.2711-2718, 2000. ,
Anatomical substrates for direct interactions between hippocampus, medial prefrontal cortex, and the thalamic nucleus reuniens, Brain Struct. Funct, vol.219, pp.911-929, 2014. ,
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation, J. Neurosci. Off. J. Soc. Neurosci, vol.27, pp.6128-6140, 2007. ,
Analysis of projections from the medial prefrontal cortex to the thalamus in the rat, with emphasis on nucleus reuniens, J. Comp. Neurol, vol.442, pp.163-187, 2002. ,
Differential projections of the infralimbic and prelimbic cortex in the rat, Synap. N. Y. N, vol.51, pp.32-58, 2004. ,
Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat, Neuroscience, vol.142, pp.1-20, 2006. ,
Efferent projections of reuniens and rhomboid nuclei of the thalamus in the rat, J. Comp. Neurol, vol.499, pp.768-796, 2006. ,
Nucleus reuniens of the midline thalamus: link between the medial prefrontal cortex and the hippocampus, Brain Res. Bull, vol.71, pp.601-609, 2007. ,
Pattern of distribution of serotonergic fibers to the thalamus of the rat, Brain Struct. Funct, vol.215, pp.1-28, 2010. ,
Chemogenetic Interrogation of a Brain-wide Fear Memory Network in Mice, Neuron, vol.94, pp.363-374, 2017. ,
Remote episodic memory deficits in patients with unilateral temporal lobe epilepsy and excisions, J. Neurosci. Off. J. Soc. Neurosci, vol.20, pp.5853-5857, 2000. ,
Chronic impairment of ERK signaling in glutamatergic neurons of the forebrain does not affect spatial memory retention and LTP in the same manner as acute blockade of the ERK pathway, Hippocampus, vol.27, pp.1239-1249, 2017. ,
Building memories: remembering and forgetting of verbal experiences as predicted by brain activity, Science, vol.281, pp.1188-1191, 1998. ,
Control of Ras cycling by Ca2+, FEBS Lett, vol.546, pp.6-10, 2003. ,
Learning induces long-term potentiation in the hippocampus, Science, vol.313, pp.1093-1097, 2006. ,
Retrograde amnesia in rats with lesions to the hippocampus on a test of spatial memory, Neuropsychologia, vol.43, pp.1580-1590, 2005. ,
Calretinin distribution in the thalamus of the rat: immunohistochemical and in situ hybridization histochemical analyses, Neuroscience, vol.50, pp.181-196, 1992. ,
Differential expression of immediate early genes in the hippocampus and spinal cord, Neuron, vol.4, pp.603-614, 1990. ,
Heterogeneity in the Dorsal Subiculum of the Rat. Distinct Neuronal Zones Project to Different Cortical and Subcortical Targets, Eur. J. Neurosci, vol.2, pp.718-725, 1990. ,
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression, Nat. Neurosci, vol.8, pp.1069-1077, 2005. ,
, , 1991.
, Constitutive expression of zif268 in neocortex is regulated by synaptic activity, Proc. Natl. Acad. Sci. U. S. A, vol.88, pp.5106-5110
Projection from the nucleus reuniens thalami to the hippocampal region: light and electron microscopic tracing study in the rat with the anterograde tracer Phaseolus vulgaris-leucoagglutinin, J. Comp. Neurol, vol.296, pp.179-203, 1990. ,
Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival, Folia Morphol, vol.52, pp.173-181, 1993. ,
Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology, Nat. Neurosci, vol.4, pp.151-158, 2001. ,
Phosphoinositide 3-kinase signalling--which way to target?, Trends Pharmacol. Sci, vol.24, pp.366-376, 2003. ,
Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism, J. Neurosci. Off. J. Soc. Neurosci, vol.16, pp.5425-5436, 1996. ,
A neural circuit for memory specificity and generalization, Science, vol.339, pp.1290-1295, 2013. ,
,
Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis, J. Neurosci. Off. J. Soc. Neurosci, vol.22, pp.1532-1540, 2002. ,
Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory, Cell, vol.107, pp.617-629, 2001. ,
Dissociation of function within the hippocampus: effects of dorsal, ventral and complete excitotoxic hippocampal lesions on spatial navigation, Neuroscience, vol.127, pp.289-300, 2004. ,
Induction and requirement of gene expression in the anterior cingulate cortex and medial prefrontal cortex for the consolidation of inhibitory avoidance memory, Mol. Brain, vol.4, p.4, 2011. ,
Transcriptional profiling reveals strict boundaries between hippocampal subregions, J. Comp. Neurol, vol.441, pp.187-196, 2001. ,
Repression of contexual fear memory induced by isoflurane is accompanied by reduction in histone acetylation and rescued by sodium butyrate, Br. J. Anaesth, vol.113, pp.634-643, 2014. ,
Ras and Rap control AMPA receptor trafficking during synaptic plasticity, Cell, vol.110, pp.443-455, 2002. ,
The primate hippocampal formation: evidence for a time-limited role in memory storage, Science, vol.250, pp.288-290, 1990. ,
, , 2013.
, The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export, Nucleic Acids Res, vol.41, pp.554-564