Programmed cell death in animal development and disease, Cell, vol.147, issue.4, pp.742-758, 2011. ,
Entosis allows timely elimination of the luminal epithelial barrier for embryo implantation, Cell reports, vol.11, issue.3, pp.358-365, 2015. ,
Cell death in health and disease, Journal of cellular and molecular medicine, vol.11, issue.6, pp.1214-1224, 2007. ,
Your neighbours matter -non-autonomous control of apoptosis in development and disease. Cell death and differentiation, vol.23, pp.1110-1118, 2016. ,
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death, Cell death and differentiation, vol.16, issue.1, pp.3-11, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00407686
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion, Cell, vol.131, issue.5, pp.966-979, 2007. ,
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death, Cell research, vol.19, issue.12, pp.1350-1362, 2009. ,
Competition between human cells by entosis, Cell research, vol.24, issue.11, pp.1299-1310, 2014. ,
Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer, EMBO molecular medicine, vol.2012, issue.9, pp.964-979 ,
URL : https://hal.archives-ouvertes.fr/hal-01016917
Induction of entosis by epithelial cadherin expression, Cell research, vol.24, issue.11, pp.1288-1298, 2014. ,
Eaten alive! Cell death by primary phagocytosis: 'phagoptosis', Trends in biochemical sciences, vol.2012, issue.8, pp.325-332 ,
Microglial phagocytosis of live neurons, Nature reviews Neuroscience, vol.15, issue.4, pp.209-216, 2014. ,
Phagoptosis -Cell Death By Phagocytosis -Plays Central Roles in Physiology, Host Defense and Pathology. Current molecular medicine, vol.15, pp.842-851, 2015. ,
Suicidal emperipolesis: a process leading to cell-in-cell structures, T cell clearance and immune homeostasis. Current molecular medicine, vol.15, pp.819-827, 2015. ,
Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation, Transfusion, vol.47, issue.9, pp.1725-1732, 2007. ,
p21 in cancer: intricate networks and multiple activities, Nat Rev Cancer, vol.9, pp.400-414, 2009. ,
Role of H2O2 in RET/PTC1 chromosomal rearrangement produced by ionizing radiation in human thyroid cells, Cancer Res, vol.70, pp.4123-4132, 2010. ,
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders, Nature, vol.479, pp.232-236, 2011. ,
Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs), Proc Natl Acad Sci U S A, vol.113, pp.6447-6456, 2016. ,
Reversal of human cellular senescence: roles of the p53 and p16 pathways, EMBO J, vol.22, pp.4212-4222, 2003. ,
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression, Cell, vol.145, pp.571-583, 2011. ,
Cellular senescence: when bad things happen to good cells, Nat Rev Mol Cell Biol, vol.8, pp.729-740, 2007. ,
Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer, EMBO Mol Med, vol.4, pp.964-979, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01016917
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis, Cell Cycle, vol.11, pp.3599-3610, 2012. ,
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice, Nat Med, vol.22, pp.78-83, 2016. ,
ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors, Science, vol.314, pp.1792-1795, 2006. ,
Cellular senescence in aging and age-related disease: from mechanisms to therapy, Nat Med, vol.21, pp.1424-1435, 2015. ,
,
, TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells, Proc Natl Acad Sci U S A, vol.108, pp.8668-8673
Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype, J Biol Chem, vol.286, pp.36396-36403, 2011. ,
p53-independent epigenetic repression of the p21(WAF1) gene in Tcell acute lymphoblastic leukemia, J Biol Chem, vol.286, pp.37639-37650, 2011. ,
Mitosis can drive cell cannibalism through entosis, 2017. ,
, , 2011.
, Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes, Nat Cell Biol, vol.13, pp.1335-1343
p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence, Nat Cell Biol, vol.11, pp.1135-1142, 2009. ,
Negative regulation of Vps34 by Cdk mediated phosphorylation, Mol Cell, vol.38, pp.500-511, 2010. ,
Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices, J Cell Biol, vol.178, pp.23-30, 2007. ,
Cannibalism by sporulating bacteria, Science, vol.301, pp.510-513, 2003. ,
p53 regulation of metabolic pathways, Cold Spring Harb Perspect Biol, vol.2, 1040. ,
Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: genetic requirements, Proc Natl Acad Sci U S A, vol.102, pp.8710-8715, 2005. ,
Entosis Is Induced by Glucose Starvation, Cell Rep, vol.20, pp.201-210, 2017. ,
The Limited in Vitro Lifetime of Human Diploid Cell Strains, Exp Cell Res, vol.37, pp.614-636, 1965. ,
Inhibition of tumor angiogenesis by p53: a new role for the guardian of the genome, J Mol Med (Berl), vol.85, pp.1175-1186, 2007. ,
Metabolic sensing by p53: keeping the balance between life and death, Proc Natl Acad Sci U S A, vol.107, pp.13193-13194, 2010. ,
Breakdown of self/nonself recognition in cannibalistic strains of the predatory slime mold, Dictyostelium caveatum, J Cell Biol, vol.102, pp.298-305, 1986. ,
Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells, Cell Death Dis, vol.4, p.856, 2013. ,
Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease, Nat Cell Biol, vol.13, pp.568-579, 2011. ,
, , 1991.
, Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6, Nature, vol.352, pp.345-347
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53, Science, vol.349, 2015. ,
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion, Cell, vol.131, issue.5, pp.966-979, 2007. ,
Characterization of the cell population mediating cytotoxicity and emperipolesis in human malignant melanomas, Trans Assoc Am Physicians, vol.94, pp.366-371, 1981. ,
Biological interaction between lymphocytes and other cells, Br J Haematol, vol.1956, issue.3, pp.283-294 ,
Suicidal emperipolesis: a process leading to cell-in-cell structures, T cell clearance and immune homeostasis, Curr Mol Med, vol.15, issue.9, pp.819-827, 2015. ,
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death, Cell Res, vol.19, issue.12, pp.1350-1362, 2009. ,
Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells, Cell Death Dis, vol.4, 2013. ,
Eaten alive! Cell death by primary phagocytosis: 'phagoptosis', Trends Biochem Sci, vol.2012, issue.8, pp.325-332 ,
Microglial phagocytosis of live neurons, Nat Rev Neurosci, vol.15, issue.4, pp.209-216, 2014. ,
Phagoptosis -Cell Death By Phagocytosis -Plays Central Roles in Physiology, Host Defense and Pathology, Curr Mol Med, vol.15, issue.9, pp.842-851, 2015. ,
Entescence is a novel senescence program initited by cellular cannibalism that prevents genomic instability and tumor progression, Cancer Cell, 2018. ,
Anticancer chemoterapy and radiotherapy trigger both non-cell-autnomous and cell-autonomous death, Cell Death Differ, 2018. ,
The human homologue of Dictyostelium discoideum phg1A is expressed by human metastatic melanoma cells, EMBO Rep, vol.10, issue.12, pp.1348-1354, 2009. ,
Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells, Cancer Res, vol.66, issue.7, pp.3629-3638, 2006. ,
Cannibalism: a way to feed on metastatic tumors, Cancer Lett, vol.258, issue.2, pp.155-164, 2007. ,
Cell-in-Cell Death Is Not Restricted by Caspase-3 Deficiency in MCF-7 Cells, J Breast Cancer, vol.19, issue.3, pp.231-241, 2016. ,
Entosis: The emerging face of non-cell-autonomous type IV programmed death, Biomed J, vol.40, issue.3, pp.133-140, 2017. ,
Reduced expression of CD47 during murine red blood cell (RBC) senescence and its role in RBC clearance from the circulation, Transfusion, vol.47, issue.9, pp.1725-1732, 2007. ,
bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages, J Exp Med, vol.179, issue.3, pp.1047-1052, 1994. ,
Entosis allows timely elimination of the luminal epithelial barrier for embryo implantation, Cell Rep, vol.11, issue.3, pp.358-365, 2015. ,
The cell biology of cell-in-cell structures, Nat Rev Mol Cell Biol, vol.9, issue.10, pp.796-809, 2008. ,
Competition between human cells by entosis, Cell Res, vol.24, issue.11, pp.1299-1310, 2014. ,
Entosis, a key player in cancer cell competition, Cell Res, vol.24, issue.11, pp.1280-1281, 2014. ,
,
, Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer, EMBO Mol Med, vol.2012, issue.9, pp.964-979
, Nat Cell Biol
p38MAPK is a novel DNA damage responseindependent regulator of the senescence-associated secretory phenotype, EMBO J, vol.30, issue.8, pp.1536-1548, 2011. ,
p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage, Genes Dev, vol.9, issue.8, pp.935-944, 1995. ,
CDK inhibitors: cell cycle regulators and beyond, Dev Cell, vol.14, issue.2, pp.159-169, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-00319908
p38 Mitogen-activated protein kinase-and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint, Mol Cell Biol, vol.29, issue.16, pp.4341-4351, 2009. ,
,
, Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination, Mol Cell, vol.5, issue.2, pp.403-410, 2000.
The p38 signal transduction pathway: activation and function, Cell Signal, vol.12, issue.1, pp.1-13, 2000. ,
NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy, Cell Death Differ, vol.24, issue.9, pp.1632-1644, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02356551
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection, J Exp Med, vol.208, issue.9, pp.1823-1834, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-02356570
Classification of cell death: recommendations of the nomenclature committee on cell Death, Cell Death Differ, vol.16, pp.3-11, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00407686
Caspase inhibition in apoptotic T cells triggers necrotic cell death depending on the cell type and the proapoptotic stimulus, J Cell Biochem, vol.97, pp.1350-61, 2006. ,
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor, J Exp Med, vol.187, pp.1477-85, 1998. ,
Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways, J Exp Med, vol.188, pp.919-949, 1998. ,
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF, Cytokine, vol.7, pp.463-70, 1995. ,
Apoptosis in the pathogenesis and treatment of disease, Science, vol.267, pp.1456-62, 1995. ,
Cell death in us and others, Science, vol.281, p.1283, 1998. ,
Fatal liaisons of p53 with Bax and Bak, Nat Cell Biol, vol.6, pp.386-394, 2004. ,
NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope, J Exp Med, vol.199, pp.629-669, 2004. ,
p53-and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa, Science, vol.302, pp.1036-1044, 2003. ,
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death, Science, vol.292, pp.727-757, 2001. ,
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells, Nature, vol.335, pp.440-442, 1988. ,
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice, Science, vol.267, pp.1506-1516, 1995. ,
, biomedical journal, vol.40, pp.133-140, 2017.
Mechanisms of apoptosis induction by the HIV-1 envelope, Cell Death Differ, vol.12, pp.916-939, 2005. ,
Regulation of mammalian autophagy in physiology and pathophysiology, Physiol Rev, vol.90, pp.1383-435, 2010. ,
Autophagy in immunity against mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy, Curr Top Microbiol Immunol, vol.335, pp.169-88, 2009. ,
Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth, J Biol Chem, vol.284, pp.1694-701, 2009. ,
Autophagy targeting of Listeria monocytogenes and the bacterial countermeasure, Autophagy, vol.7, pp.310-314, 2011. ,
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle, Cell Host Microbe, vol.11, pp.33-45, 2012. ,
Autophagy: renovation of cells and tissues, Cell, vol.147, pp.728-769, 2011. ,
Autophagosome formation: core machinery and adaptations, Nat Cell Biol, vol.9, pp.1102-1111, 2007. ,
Growing roles for the mTOR pathway, Curr Opin Cell Biol, vol.17, pp.596-603, 2005. ,
The role of Atg proteins in autophagosome formation, Annu Rev Cell Dev Biol, vol.27, pp.107-139, 2011. ,
Autophagy in cell death: an innocent convict?, J Clin Invest, vol.115, pp.2679-88, 2005. ,
Autosis and autophagic cell death: the dark side of autophagy, Cell Death Differ, vol.22, pp.367-76, 2015. ,
Autosis is a Naþ,Kþ-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia, Proc Natl Acad Sci, vol.110, pp.20364-71, 2013. ,
Cell death, N Engl J Med, vol.361, pp.1570-83, 2009. ,
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury, Nat Chemical Biol, vol.1, pp.112-121, 2005. ,
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation, Cell, vol.137, pp.1112-1135, 2009. ,
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha, Cell, vol.137, pp.1100-1111, 2009. ,
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis, Science, vol.325, pp.332-338, 2009. ,
Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity, Cell Rep, vol.15, pp.274-87, 2016. ,
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death, Cell Death Differ, vol.19, pp.107-127, 2012. ,
Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis, Nat Cell Biol, vol.5, pp.733-773, 2003. ,
The cornified envelope: a model of cell death in the skin, Nat Rev Mol Cell Biol, vol.6, pp.328-368, 2005. ,
A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion, Cell, vol.131, pp.966-79, 2007. ,
Regulation of cell death: the calcium-apoptosis link, Nat Rev Mol Cell Biol, vol.4, pp.552-65, 2003. ,
Death through a tragedy: mitotic catastrophe, Cell death and Differ, vol.15, pp.1153-62, 2008. ,
Unconventional roles of the NADPH oxidase: signaling, ion homeostasis, and cell death, Sci STKE, p.11, 2007. ,
An alternative, nonapoptotic form of programmed cell death, Proc Natl Acad Sci, vol.97, pp.14376-81, 2000. ,
Parthanatos, a messenger of death, Front Biosci, vol.14, pp.1116-1144, 2009. ,
Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC, Cell Host Microbe, vol.2, pp.147-59, 2007. ,
Salmonella induces macrophage death by caspase-1-dependent necrosis, Mol Microbiol, vol.38, pp.31-40, 2000. ,
Axonal self-destruction and neurodegeneration, Science, vol.296, pp.868-71, 2002. ,
The cell biology of cell-in-cell structures, Nat Rev Mol Cell Biol, vol.9, pp.796-809, 2008. ,
Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury, Am J Respir Crit Care Med, vol.184, pp.547-60, 2011. ,
Induction of entosis by epithelial cadherin expression, Cell Res, vol.24, pp.1288-98, 2014. ,
Mechanisms and consequences of entosis, Cell Mol Life Sci, vol.73, pp.2379-86, 2016. ,
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death, Cell Res, vol.19, pp.1350-62, 2009. ,
Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer, EMBO Mol Med, vol.4, pp.964-79, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01016917
PIKfyve regulates vacuole maturation and nutrient recovery following engulfment, Dev Cell, vol.38, pp.536-583, 2016. ,
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes, Nat Cell Biol, vol.13, pp.1335-1378, 2011. ,
Tumor cell-tumor cell emperipolesis, Exp Cell Res, vol.48, pp.229-260, 1967. ,
Biological interaction between lymphocytes and other cells, Br J Haematol, vol.2, pp.283-94, 1956. ,
Emperipolesis of hematopoietic cells in myelocytic leukemia. Electron microscopic and phase biomedical journal 40 (2017) 133e140 contrast microscopic studies, Cell Pathol Incl Mol Pathol, vol.35, pp.283-90, 1981. ,
The human homologue of Dictyostelium discoideum phg1A is expressed by human metastatic melanoma cells, EMBO Rep, vol.10, pp.1348-54, 2009. ,
Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells, Cancer Res, vol.66, pp.3629-3667, 2006. ,
Cell cannibalism in ductal carcinoma of breast, Cytopathology, vol.17, pp.304-309, 2006. ,
Cell cannibalism: diagnostic marker of malignancy, Diagn Cytopathol, vol.28, pp.86-93, 2003. ,
Clinical significance of "cannibalism" in urinary cytology of bladder cancer, Acta Cytol, vol.42, pp.1365-1374, 1998. ,
Cytologic findings of medulloblastoma in crush smears, Acta Cytol, vol.45, pp.542-548, 2001. ,
A non-genetic route to aneuploidy in human cancers, Nat Cell Biol, vol.13, pp.324-354, 2011. ,
Mechanisms of ploidy increase in human cancers: a new role for cell cannibalism, Cancer Res, vol.72, pp.1596-601, 2012. ,
Entosis allows timely elimination of the luminal epithelial barrier for embryo implantation, Cell Rep, vol.11, pp.358-65, 2015. ,
Fine-needle aspiration biopsy of pleomorphic (giant cell) carcinoma of the pancreas. Cytologic, immunocytochemical, and ultrastructural findings, Am J Clin Pathology, vol.89, pp.714-734, 1988. ,
PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments, Cancer Biol Ther, vol.9, pp.764-77, 2010. ,
Cell-in-cell structures are involved in the competition between cells in human tumors, Mol Cell Oncol, vol.2, p.1002707, 2015. ,
Suicidal emperipolesis: a process leading to cell-in-cell structures, T cell clearance and immune homeostasis, Curr Mol Med, vol.15, pp.819-846, 2015. ,
Morphological evidence of neutrophil-tumor cell phagocytosis (cannibalism) in human gastric adenocarcinomas, Ultrastruct Pathol, vol.26, pp.315-336, 2002. ,
Cannibalism: a way to feed on metastatic tumors, Cancer Lett, vol.258, pp.155-64, 2007. ,
Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells, Cell Death Dis, vol.4, p.856, 2013. ,
Cell-in-cell structures formed between human cancer cell lines and the cytotoxic regulatory T-cell line HOZOT, J Mol Cell Biol, vol.2, pp.139-51, 2010. ,
Eaten alive! Cell death by primary phagocytosis: 'phagoptosis', Trends Biochem Sci, vol.37, pp.325-357, 2012. ,
Microglial phagocytosis of live neurons, Nat Rev Neurosci, vol.15, pp.209-225, 2014. ,
Phagoptosis e cell Death by phagocytosis e plays central roles in physiology, host defense and pathology, Curr Mol Med, vol.15, pp.133-140, 2015. ,
Cells Expressing the C/EBPbeta Isoform, LIP, Engulf Their Neighbors, Plos ONE, vol.7, issue.7, 2012. ,
A complex secretory program orchestrated by the inflammasome controls paracrine senescence, Nature Cell Biology, vol.15, issue.8, pp.978-990, 2013. ,
Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence, Cell, vol.133, issue.6, pp.1006-1018, 2008. ,
,
Essential Role of p38? MAP Kinase in Placental but Not Embryonic Cardiovascular Development, Molecular Cell, vol.6, issue.1, pp.14-20, 2000. ,
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci, The Journal Of Cell Biology, vol.215, issue.3, pp.325-334, 2016. ,
Involvement of the cyclindependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts, Proceedings Of The National Academy Of Sciences, vol.93, issue.24, pp.13742-13747, 1996. ,
Playing games with epigenetics, Nature Reviews Cancer, vol.9, issue.7, pp.456-456, 2009. ,
,
I?B? is is a regulator of the senescence-associated secretory phenotype in DNA damage-and oncogene-induced senescence, Journal Of Cell Science, vol.126, issue.16, pp.3738-3745, 2013. ,
Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2, Biogerontology, vol.17, issue.2, pp.305-315, 2015. ,
p53-Independent Regulation of p21Waf1/Cip1 Expression and Senescence by Chk2, Molecular Cancer Research, vol.3, issue.11, pp.627-634, 2005. ,
,
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2, Science, issue.5428, pp.736-739, 1999. ,
,
Cell cannibalism as an indicator of anaplasia and tumor aggressiveness in carcinoma breast, Journal Of Advance Researches In Biological Sciences, vol.5, issue.3, pp.286-289, 2012. ,
The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages, Crit Rev Oncol Hematol, vol.66, issue.1, pp.1-9, 2008. ,
Acceleratori per la salute. Asimmetrie, Rivista Trimestrale Dell'Istitut O Nazionale Di Fisica Nucleare, vol.6, p.21, 2008. ,
Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity, Cytoskeleton, vol.67, issue.9, pp.545-554, 2010. ,
A module of negative feedback regulators defines growth factor signaling, Nature Genetics, vol.39, issue.4, pp.503-512, 2007. ,
,
, p38 Mitogen-Activated Protein Kinase Activity Commits Embryonic Stem Cells to Either Neurogenesis or, 2006.
, Cardiomyogenesis. Stem Cells, vol.24, issue.5, pp.1399-1406
, , 2014.
, Elucidating Sources and Roles of Granzymes A and B during Bacterial Infection and Sepsis, Cell Reports, vol.8, issue.2, pp.420-429
Role of BNIP3 in proliferation and hypoxia-induced autophagy: implications for personalized cancer therapies, Annals Of The New York Academy Of Sciences, vol.1210, issue.1, pp.8-16, 2010. ,
,
Targeted deletion of autophagy-related 5(atg5) impairs adipogenesis in a cellular model and in mice, Autophagy, vol.5, issue.8, pp.1118-1130, 2009. ,
Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome, Pharmaceuticals, vol.3, issue.12, pp.1842-1872, 2010. ,
,
The selectivity of protein kinase inhibitors: a further update, Biochemical Journal, vol.408, issue.3, pp.297-315, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00478827
,
,
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders, Nature, vol.479, issue.2, pp.232-238, 2011. ,
The tumor microenvironment at a glance, Journal Of Cell Science, vol.125, issue.23, pp.5591-5596, 2012. ,
Cell Cannibalism: A cytological study in effusion samples, Journal Of Cytology, vol.28, issue.2, 2011. ,
Hypoxia-inducible factor-1 and oncogenic signaling, Bioessays, vol.26, issue.3, pp.262-269, 2004. ,
Regulation of GLUT1, 1999. ,
, Gene Transcription by the Serine/Threonine Kinase Akt1, Journal Of Biological Chemistry, vol.274, issue.29, pp.20281-20286
Cancer cells enter dormancy after cannibalizing mesenchymal stem/stromal cells (MSCs), Proceedings Of The National Academy Of Sciences, vol.113, pp.6447-6456, 2016. ,
Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse, Journal Of Clinical Oncology, vol.24, issue.34, pp.5373-5380, 2006. ,
The birds' eye cell: Cannibalism or abnormal division of tumor cells, Acta Cytol, issue.92, p.25, 1981. ,
The current state of eukaryotic DNA base damage and repair, Nucleic Acids Research, 1136. ,
Cell senescence is an antiviral defense mechanism, Scientific Reports, vol.6, issue.1, 2016. ,
,
Exposure of N-acetylglucosamine decreases early in dexamethasoneinduced apoptosis in thymocytes, demonstrated by flow cytometry using wheat germ agglutinin and pokeweed mitogen, Immunology And Cell Biology, vol.77, issue.3, pp.224-235, 1999. ,
The p38? Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the ?-G Helix and MAPK Insert, Journal Of Biological Chemistry, vol.289, issue.34, pp.23546-23556, 2014. ,
Chaperone-Mediated Autophagy, Proceedings Of The American Thoracic Society, vol.7, issue.1, pp.29-39, 2010. ,
Hepatocyte entry leads to degradation of autoreactive CD8 T cells, Proceedings Of The National Academy Of Sciences, vol.108, issue.40, pp.16735-16740, 2011. ,
Angiogenesis: Tumorigenesis and the angiogenic switch, Nature Reviews Cancer, vol.3, issue.6, pp.401-410, 2003. ,
Regulated necrosis: the expanding network of non-apoptotic cell death pathways, Nature Reviews Molecular Cell Biology, vol.15, issue.2, pp.135-147, 2014. ,
Pyroptosis: host cell death and inflammation, Nature Reviews Microbiology, vol.7, issue.2, pp.99-109, 2009. ,
MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8, Aging, vol.1, issue.4, pp.402-411, 2009. ,
Stromal fibroblasts in cancer initiation and progression, Nature, vol.432, issue.7015, pp.332-337, 2004. ,
Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis, JNCI: Journal Of The National Cancer Institute, issue.8, p.109, 2017. ,
The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies, The Journal Of Pathology, vol.196, issue.3, pp.254-265, 2002. ,
,
Structure and function of telomeres, Nature, vol.350, issue.6319, pp.569-573, 1991. ,
,
Telomeres and human disease: ageing, cancer and beyond, Nature Reviews Genetics, vol.6, issue.8, pp.611-622, 2005. ,
, , 2011.
, Cleavage of Annexin A1 by ADAM10 during Secondary Necrosis Generates a Monocytic "Find-Me, Signal. The Journal Of Immunology, vol.188, issue.1, pp.135-145
Cell Surface Externalization of Annexin A1 as a Failsafe Mechanism Preventing Inflammatory Responses during Secondary Necrosis, The Journal Of Immunology, vol.183, issue.12, pp.8138-8147, 2009. ,
,
Mechanism of Telomerase Induction during T Cell Activation, Experimental Cell Research, vol.228, issue.1, pp.58-64, 1996. ,
Role of the SCFSkp2Ubiquitin Ligase in the Degradation of p21Cip1in S Phase, Journal Of Biological Chemistry, vol.278, issue.28, pp.25752-25757, 2003. ,
Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence-derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell-mediated Lysis, The Journal Of Experimental Medicine, vol.187, issue.5, pp.813-818, 1998. ,
Serpins prevent granzymeinduced death in a species-specific manner, Immunology And Cell Biology, vol.84, issue.1, pp.79-86, 2006. ,
,
Orphan granzymes find a home, Immunological Reviews, vol.235, issue.1, pp.117-127, 2010. ,
Combating subclonal evolution of resistant cancer phenotypes, Nature Communications, vol.8, issue.1, 2017. ,
,
Mechanism of p38 MAP kinase activation in vivo, Genes & Development, vol.17, issue.16, pp.1969-1978, 2003. ,
,
The permeability transition pore complex in cancer cell death, Oncogene, vol.25, issue.34, pp.4744-4756, 2006. ,
An osmosensing signal transduction pathway in yeast, Science, vol.259, issue.5102, pp.1760-1763, 1993. ,
The principles of cancer staging, 2016. ,
, , vol.10
Eaten alive! Cell death by primary phagocytosis: 'phagoptosis', Trends In Biochemical Sciences, vol.37, issue.8, pp.325-332, 2012. ,
Phagoptosis -cell death by phagocytosis -plays central roles in physiology, host defense and pathology, Current Molecular Medicine, vol.15, issue.999, pp.1-1, 2015. ,
,
CTLA-4 and PD-1 Pathways, American Journal Of Clinical Oncology, vol.39, issue.1, pp.98-106, 2016. ,
Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis, Cell Death & Differentiation, vol.8, issue.5, pp.443-450, 2001. ,
,
The cGAS-cGAMPS-STING pathway of cytosolic DNA sensing and signaling, Molecular Cell, vol.54, issue.2, pp.289-96, 2014. ,
Cellular senescence: when bad things happen to good cells, Nature Reviews Molecular Cell Biology, vol.8, issue.9, pp.729-740, 2007. ,
The cornified envelope: a model of cell death in the skin, 2005. ,
VEGF as a Key Mediator of Angiogenesis in Cancer, Oncology, vol.69, issue.3, pp.4-10, 2005. ,
,
Cell death by mitotic catastrophe: a molecular definition, Oncogene, vol.23, issue.16, pp.2825-2837, 2004. ,
,
Increased and pathologic emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1low mice, Blood, vol.104, issue.12, pp.3573-3580, 2004. ,
A Perspective on Cancer Cell Metastasis, Science, vol.331, issue.6024, pp.1559-1564, 2011. ,
Radiation-induced autophagy: mechanisms and consequences, Free Radical Research, vol.50, issue.3, pp.273-290, 2016. ,
,
Interdigital cell death can occur through a necrotic and caspase-independent pathway, Current Biology, vol.9, issue.17, pp.967-968, 1999. ,
, , pp.80425-80429
The E2F transcription factor is a cellular target for the RB protein, Cell, vol.65, issue.6, pp.1053-1061, 1991. ,
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis, Nature, vol.436, issue.7051, pp.725-730, 2005. ,
,
The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation, The Journal Of Cell Biology, vol.206, issue.2, pp.173-182, 2014. ,
, Transforming Growth Factor-Signaling, 2008.
, Deficient Fibroblasts Enhance Hepatocyte Growth Factor Signaling in Mammary Carcinoma Cells to Promote Scattering and Invasion, Molecular Cancer Research, vol.6, issue.10, pp.1521-1533
,
Metallothioneins in human tumors and potential roles in carcinogenesis. Mutation Research/Fundamental And Molecular Mechanisms Of Mutagenesis, vol.533, pp.201-209, 2003. ,
Selective Phagocytosis of Nucleated Erythrocytes by Cytotoxic Amebae in Cell Culture, Science, vol.130, issue.3391, pp.1763-1764, 1959. ,
Do stress-related psychosocial factors contribute to cancer incidence and survival?, Nature Clinical Practice Oncology, vol.5, issue.8, pp.466-475, 2008. ,
,
Perspectives on the therapeutic modulation of an alternative cell death, programmed necrosis (Review), International Journal Of Molecular Medicine, vol.33, issue.6, pp.1401-1406, 2014. ,
,
Death by a Thousand Cuts: Granzyme Pathways of Programmed Cell Death, Annual Review Of Immunology, vol.26, issue.1, pp.389-420, 2008. ,
,
p38 Mitogen-Activated Protein Kinase Pathways in Asthma and COPD, Chest, vol.139, issue.6, pp.1470-1479, 2011. ,
The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look, The Open Rheumatology Journal, vol.6, issue.1, pp.209-219, 2012. ,
Modes of cancer cell invasion and the role of the microenvironment, Current Opinion In Cell Biology, vol.36, pp.13-22, 2015. ,
NUPR1 Interacts with p53, Transcriptionally Regulates p21 and Rescues Breast Epithelial Cells from Doxorubicin-Induced Genotoxic Stress, Current Cancer Drug Targets, vol.8, issue.5, pp.421-430, 2008. ,
,
Nineteenth century research on naturally occurring cell death and related phenomena, Anatomy And Embryology, vol.193, issue.2, 1996. ,
Wallerian Degeneration, WldS, and Nmnat, Annual Review Of Neuroscience, vol.33, issue.1, pp.245-267, 2010. ,
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I, Nature Cell Biology, vol.3, issue.4, pp.339-345, 2001. ,
,
Tumour biology: Senescence in premalignant tumours, Nature, vol.436, issue.7051, pp.642-642, 2005. ,
Senescence in tumours: evidence from mice and humans, Nature Reviews Cancer, vol.10, issue.1, pp.51-57, 2010. ,
Cellular Senescence in Cancer and Aging, Cell, vol.130, issue.2, pp.223-233, 2007. ,
Telomerase in the human organism, Oncogene, vol.21, issue.4, pp.564-579, 2002. ,
,
A novel cell typespecific role of p38? in the control of autophagy and cell death in colorectal cancer cells, Cell Death And Differentiation, vol.14, issue.4, pp.693-702, 2006. ,
Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis, Cell, vol.124, issue.2, pp.263-266, 2006. ,
H. pylori infection and gastric cancer: State of the art, International Journal Of Oncology, vol.42, issue.1, pp.5-18, 2012. ,
,
, , 2008.
, Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor, PLoS Biol, vol.6, issue.12, p.301
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression, Annual Review Of Pathology: Mechanisms Of Disease, vol.5, issue.1, pp.99-118, 2010. ,
,
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype, Journal Of Biological Chemistry, vol.286, issue.42, pp.36396-36403, 2011. ,
,
Stem cells and the repair of radiation-induced salivary gland damage, Oral Diseases, vol.17, issue.2, pp.143-153, 2010. ,
p38MAPK: stress responses from molecular mechanisms to therapeutics, Trends In Molecular Medicine, vol.15, issue.8, pp.369-379, 2009. ,
,
Many roads lead to oncogene-induced senescence, 2008. ,
, Oncogene, vol.27, issue.20, pp.2801-2809
A Drosophila p38 orthologue is required for environmental stress responses, EMBO Reports, vol.5, issue.11, pp.1058-1063, 2004. ,
,
Caspase-activation pathways in apoptosis and immunity, 2003. ,
, Immunological Reviews, vol.193, issue.1, pp.10-21
Mechanisms and functions of p38 MAPK signaling, Biochemical Journal, vol.429, issue.3, pp.403-417, 2010. ,
Chaperone-mediated autophagy: roles in disease and aging, Cell Research, vol.24, issue.1, pp.92-104, 2013. ,
Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis, Apoptosis In Cancer Pathogenesis And Anti-Cancer Therapy, vol.930, pp.89-112, 2016. ,
Combined inhibition of TGF? and PDGF signaling attenuates radiation-induced pulmonary fibrosis, Oncoimmunology, vol.5, issue.5, 2015. ,
Downregulation of Cytokine-induced Interleukin-8 Requires Inhibition of p38 Mitogen-activated Protein Kinase (MAPK) via MAPK Phosphatase 1-dependent and -independent Mechanisms, Journal Of Biological Chemistry, vol.286, issue.18, pp.15998-16007, 2011. ,
Cancer: an old disease, a new disease or something in between?, Nature Reviews Cancer, vol.10, issue.10, pp.728-733, 2010. ,
Parthanatos, a messenger of death, Frontiers In Bioscience, issue.14, p.1116, 2009. ,
Analysis of the genome to personalize therapy for melanoma, Oncogene, vol.29, issue.41, pp.5545-5555, 2010. ,
Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells, Biochemical Journal, vol.413, issue.1, pp.185-191, 2008. ,
,
, , 2006.
, Phosphorylation by p38MAPK : identification of target sites and biological consequences, J Biol Chem, vol.28, issue.30, pp.21353-61
The role of radiation therapy in bone metastases management, Oncotarget, vol.8, issue.15, 2017. ,
Erratum: Addendum: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury, Nature Chemical Biology, vol.9, issue.3, pp.192-192, 2013. ,
Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase, Cell Death & Differentiation, vol.20, issue.2, pp.366-366, 2012. ,
Pro-Oncogenic Role of Alternative p38 Mitogen-Activated Protein Kinases p38? and p38?, linking Inflammation and Cancer in Colitis-Associated Colon Cancer, Cancer Research, vol.74, issue.21, pp.6150-6160, 2014. ,
,
The role of radiotherapy in cancer treatment, Cancer, vol.104, issue.6, pp.1129-1137, 2005. ,
Rapamycin decelerates cellular senescence, Cell Cycle, vol.8, issue.12, pp.1888-1895, 2009. ,
,
Caspase-14 reveals its secrets, The Journal Of Cell Biology, vol.180, issue.3, pp.451-458, 2008. ,
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in, 2014. ,
, Immunogenic Tumors. Immunity, issue.5, pp.843-852
Cip/Kip proteins: more than just CDKs inhibitors, Genes & Development, vol.18, issue.8, pp.851-855, 2004. ,
Hypoxia, HIF1 and glucose metabolism in the solid tumour, Nature Reviews Cancer, vol.8, issue.9, pp.705-713, 2008. ,
Autophagy, Immunity, and Microbial Adaptations, Cell Host & Microbe, vol.5, issue.6, pp.527-549, 2009. ,
, , 2009.
, Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody, Clinical Cancer Research, vol.15, issue.17, pp.5379-88
Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer, Nature Cell Biology, vol.13, issue.3, pp.292-302, 2011. ,
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death, Cell, vol.149, issue.5, pp.1060-1072, 2012. ,
,
p38? MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis, Cancer Cell, vol.11, issue.2, pp.191-205, 2007. ,
,
Targeting Mitosis in Cancer: Emerging Strategies, Molecular Cell, vol.60, issue.4, pp.524-536, 2015. ,
,
,
Cytoplasmic chromatin triggers inflammation in senescence and cancer, Nature, vol.550, issue.7676, pp.402-406, 2017. ,
Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade, Cancer Research, vol.74, issue.19, pp.5458-5468, 2014. ,
Stem Cells, Their Niches and the Systemic Environment: An Aging Network, Genetics, vol.180, issue.4, pp.1787-1797, 2008. ,
Staurosporine Induces Necroptotic Cell Death under Caspase-Compromised Conditions in U937 Cells, Plos ONE, vol.7, issue.7, 2012. ,
The Three Es of Cancer Immunoediting, Annual Review Of Immunology, vol.22, issue.1, pp.329-360, 2004. ,
Mitosis can drive cell cannibalism through entosis, 2017. ,
Secondary Malignancy Risk Following Proton Radiation Therapy, Frontiers In Oncology, 2015. ,
Identification of Novel Mammalian Caspases Reveals an Important Role of Gene Loss in Shaping the Human Caspase Repertoire, Molecular Biology And Evolution, vol.25, issue.5, pp.831-841, 2008. ,
Apoptosis: A Review of Programmed Cell Death, Toxicologic Pathology, vol.35, issue.4, pp.495-516, 2007. ,
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms, The EMBO Journal, vol.19, issue.6, pp.1301-1311, 2000. ,
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-?B-Dependent Manner, Cancer Cell, vol.17, issue.2, pp.135-147, 2010. ,
Radiation-induced cell death mechanisms, Tumor Biology, vol.31, issue.4, pp.363-372, 2010. ,
A Matter of Life and Cell Death, Science, vol.281, issue.5381, pp.1317-1322, 1998. ,
,
A DNA damage checkpoint response in telomere-initiated senescence, Nature, vol.426, issue.6963, pp.194-198, 2003. ,
,
A brief history of cancer: Age-old milestones underlying our current knowledge database, International Journal Of Cancer, vol.136, issue.9, pp.2022-2036, 2014. ,
Cannibalism: A way to feed on metastatic tumors, Cancer Letters, vol.258, issue.2, pp.155-164, 2007. ,
,
, , 2012.
, Aging, vol.4, issue.5, pp.330-349
Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38 at Thr50 promotes microtubule assembly, Journal Of Cell Science, vol.118, issue.2, pp.397-408, 2005. ,
The machinery of macroautophagy, Cell Research, vol.24, issue.1, pp.24-41, 2013. ,
The coordiante regulation of the p53 and mTor pathways in cells, Proc Natl Acad Sci, vol.102, issue.23, pp.8204-8213, 2005. ,
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012, International Journal Of Cancer, vol.136, issue.5, pp.359-386, 2014. ,
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response, Biochimica Et Biophysica Acta (BBA) -Bioenergetics, vol.1757, issue.9, pp.1371-1387, 2006. ,
,
Transglutaminase 2 in the balance of cell death and survival, FEBS Letters, vol.579, issue.15, pp.3297-3302, 2005. ,
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells, Infection And Immunity, vol.73, issue.4, pp.1907-1916, 2005. ,
Daphnetin induced differentiation of human renal carcinoma cells and its mediation by p38 mitogen-activated protein kinase, Biochemical Pharmacology, vol.67, issue.9, pp.1779-1788, 2004. ,
,
Census and evaluation of p53 target genes, Oncogene, vol.36, pp.3943-3956, 2017. ,
,
The two faces of IL-6 in the tumor microenvironment, 2014. ,
, Seminars In Immunology, vol.26, issue.1, pp.38-47
Autophagy proteins in macroendocytic engulfment, Trends In Cell Biology, vol.22, issue.7, pp.374-380, 2012. ,
Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes, Nature Cell Biology, vol.13, issue.11, pp.1335-1343, 2011. ,
Killers creating new life: caspases drive apoptosis-induced proliferation in tissue repair and disease, Cell Death And Differentiation, vol.24, issue.8, pp.1390-1400, 2017. ,
,
Signaling Functions of Reactive Oxygen Species, Biochemistry, vol.49, issue.5, pp.835-842, 2010. ,
Systemic effects of local radiotherapy, The Lancet Oncology, vol.10, issue.7, pp.718-726, 2009. ,
Radiation Therapy to Convert the Tumor Into an In Situ Vaccine, International Journal Of Radiation Oncology*Biology*Physics, vol.84, issue.4, pp.879-880, 2012. ,
,
Soft Tissue Tumors in Palaeopathology: A Review, Pathobiology, vol.79, issue.5, pp.257-267, 2012. ,
Soft Tissue Tumors in Palaeopathology: A Review, Pathobiology, vol.79, issue.5, pp.257-267, 2012. ,
Revisiting the hallmarks of cancer, Am J Cancer Res, vol.1, issue.7, pp.1016-1036, 2017. ,
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans, Mech Ageing Dev, vol.128, issue.1, pp.92-105, 2007. ,
Vessel cooption mediates resistance to anti-angiogenic therapy in liver metastases, Nature Medicine, vol.22, issue.11, pp.1294-1302, 2016. ,
p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype, The EMBO Journal, vol.30, issue.8, pp.1536-1548, 2011. ,
,
MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation, Journal Of Neuroscience, vol.32, issue.8, pp.2657-2666, 2012. ,
,
The immune contexture in human tumours: impact on clinical outcome, Nature Reviews Cancer, vol.12, issue.4, pp.298-306, 2012. ,
Tube Travel: The Role of Proteases in Individual and Collective Cancer Cell Invasion, Cancer Research, vol.68, issue.18, pp.7247-7249, 2008. ,
, Cancer Invasion and the Microenvironment: Plasticity and Reciprocity, 2011.
, Cell, vol.147, issue.5, pp.992-1009
The Beclin 1-VPS34 complex -at the crossroads of autophagy and beyond, Trends In Cell Biology, vol.20, issue.6, pp.355-362, 2010. ,
Coordinated regulation of myeloid cells by tumours, Nature Reviews Immunology, vol.12, issue.4, pp.253-268, 2012. ,
Cooperation between C1q and DNase I in the clearance of necrotic cell-derived chromatin, Arthritis & Rheumatism, vol.50, issue.2, pp.640-649, 2004. ,
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death, Cell Death & Differentiation, vol.19, issue.1, pp.107-120, 2011. ,
Immunogenic cell death in radiation therapy, 2013. ,
, e26536, vol.2
, , 2015.
, Autophagy in malignant transformation and cancer progression, The EMBO Journal, vol.34, issue.7, pp.856-880
,
The modulation of host cell apoptosis by intracellular bacterial pathogens, Trends In Microbiology, vol.8, issue.7, pp.306-313, 2000. ,
Stages of cell cannibalism-entosis-in normal human keratinocyte culture, Biochemistry (Moscow), vol.80, issue.11, pp.1469-1477, 2015. ,
,
Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte, Cell, vol.123, issue.2, pp.321-334, 2005. ,
, Heat Shock Proteins, vol.27, pp.2592-2601, 2006.
URL : https://hal.archives-ouvertes.fr/inserm-02534045
,
Generation of MHC class I diversity in primary tumors and selection of the malignant phenotype, International Journal Of Cancer, vol.138, issue.2, pp.271-280, 2014. ,
,
Early Detection of Potential Cannibalistic Cells Before Any Morphological Evidence of Cannibalism Using CD68 and Lysozyme in Oral Squamous Cell Carcinoma, International Journal Of Radiation Oncology Biology Physics, vol.94, issue.4, 2016. ,
MAPKK-Independent Activation of p38alpha mediated by TAB1-Dependent Autophosphorylation of p38alpha, Science, vol.295, issue.5558, pp.1291-1294, 2002. ,
MAPK signaling pathways in the regulation of hematopoiesis, Journal Of Leukocyte Biology, vol.86, issue.2, pp.237-250, 2009. ,
Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215, Cancer Research, vol.68, issue.24, pp.10105-10112, 2008. ,
, , 2012.
, Physiological Interaction of Heart and Lung in Thoracic Irradiation, International Journal Of Radiation Oncology Biology Physics, vol.84, issue.5, pp.639-646
Induction of pRb Degradation by the Human Papillomavirus Type 16 E7 Protein Is Essential To Efficiently Overcome p16INK4a-Imposed G1 Cell Cycle Arrest, Journal Of Virology, vol.75, issue.10, pp.4705-4712, 2001. ,
,
, Anoikis. Cell Death And Differentiation, vol.12, pp.1473-1477, 2005.
,
Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins, Trends In Endocrinology & Metabolism, vol.26, issue.4, pp.165-175, 2015. ,
,
p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage, Journal Of Cellular Physiology, vol.221, issue.3, pp.594-602, 2009. ,
Autophagy: cellular and molecular mechanisms, The Journal Of Pathology, vol.221, issue.1, pp.3-12, 2010. ,
, Fact Sheets by Population, Globocan.iarc.fr. Retrieved, 2012.
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence, Nat Cell Biol, vol.19, issue.9, pp.1061-1070, 2017. ,
The Effect of Gamma Radiation on Cellsin VivoPart II, The British Journal Of Radiology, vol.12, issue.140, pp.486-498, 1939. ,
Barcellos-Hofff ,
Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death, Oncoimmunology, vol.3, 2014. ,
Cell death by necrosis: towards a molecular definition, Trends In Biochemical Sciences, vol.32, issue.1, pp.37-43, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00165336
Gene therapy for carcinoma of the breast: Pro-apoptotic gene therapy, Breast Cancer Research, vol.2, issue.1, 1999. ,
Cannibalism by Sporulating Bacteria, Science, vol.301, issue.5632, pp.510-513, 2003. ,
The Hallmarks of Cancer and the Radiation Oncologist: Updating the 5Rs of Radiobiology, Clinical Oncology, vol.25, issue.10, pp.569-577, 2013. ,
Phagocytosis: An Immunobiologic Process, Immunity, vol.44, issue.3, pp.463-475, 2016. ,
,
Oncogene-induced senescence: the bright and dark side of the response, Current Opinion In Cell Biology, vol.22, issue.6, pp.816-827, 2010. ,
Autophagy as a cell death and tumor suppressor mechanism, Oncogene, vol.23, issue.16, pp.2891-2906, 2004. ,
Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung, Cancer Cell, vol.20, issue.3, pp.300-314, 2011. ,
,
The Pathophysiology of Mitochondrial Cell Death, Science, issue.5684, pp.626-629, 2004. ,
, Immunity, Inflammation, and Cancer. Cell, vol.140, issue.6, pp.883-899, 2010.
Priority in the Therapeutic Use of X-rays, Radiology, vol.21, issue.2, pp.156-162, 1933. ,
,
Autophagy and apoptosis : What is the connection ?, Trends in Cell Biology, vol.21, issue.7, pp.387-392, 2011. ,
Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27, J Cell Sci, vol.110, pp.357-68, 1997. ,
The Role of Telomeres in, Stem Cells and Cancer. Cell, vol.152, issue.3, pp.390-393, 2013. ,
Herpes Simplex Virus Suppresses Necroptosis in Human Cells, Cell Host & Microbe, vol.17, issue.2, pp.243-251, 2015. ,
,
Cell cannibalism: Diagnostic marker of malignancy, Diagnostic Cytopathology, vol.28, issue.2, pp.86-87, 2003. ,
Emperipolesis, entosis and cell cannibalism: Demystifying the cloud, Journal Of Oral And Maxillofacial Pathology, vol.21, issue.1, p.92, 2017. ,
p38? Mediates Cell Survival in Response to Oxidative Stress via Induction of Antioxidant Genes, Journal Of Biological Chemistry, vol.287, issue.4, pp.2632-2642, 2011. ,
, Crystal Structure of the P38?-MAPKAP Kinase, 2007.
, Journal Of Biological Chemistry, vol.282, issue.13, pp.9733-9739
,
The morphology of apoptosis, Cell And Tissue Research, vol.301, issue.1, pp.5-17, 2000. ,
,
Entosis Is Induced by Glucose Starvation, Oncotarget, vol.8, issue.35, pp.57934-57935, 2017. ,
,
Targeting CDK4/6 in patients with cancer, Cancer Treatment Reviews, vol.45, pp.129-138, 2016. ,
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells, Science, vol.265, issue.5173, pp.808-811, 1994. ,
A Conserved p38 Mitogen-Activated Protein Kinase Pathway Regulates Drosophila Immunity Gene Expression, Molecular And Cellular Biology, vol.18, issue.6, pp.3527-3539, 1998. ,
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment, Cancer Cell, vol.21, issue.3, pp.309-322, 2012. ,
Hallmarks of Cancer: The Next Generation, Cell, vol.144, issue.5, pp.646-674, 2011. ,
,
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease, Trends In Molecular Medicine, vol.15, issue.3, pp.112-119, 2009. ,
,
The role of p38 MAPK in TGF-beta-1-induced signal transduction in human neutrophils, Biochem Biophys Res Commun, vol.246, issue.1, pp.55-63, 1998. ,
,
Type I and Type II pathways of Fas-mediated Apoptosis are differentially controlled by XIA, Journal of Molecular Cell Biology, vol.2, issue.2, pp.63-64, 2010. ,
, , 2006.
, Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice, Nature, issue.7095, pp.885-889
Stress-activated Protein Kinase-3 Interacts with the PDZ Domain of ?1-Syntrophin, Journal Of Biological Chemistry, vol.274, issue.18, pp.12626-12631, 1999. ,
Cell Cannibalism and Nucleus-Fragmented Cells in Voided Urine, Acta Cytologica, vol.51, issue.4, pp.547-551, 2007. ,
,
A time to kill: viral manipulation of the cell death program, Journal Of General Virology, vol.83, issue.7, pp.1547-1564, 2002. ,
The serial cultivation of human diploid cell strains, Experimental Cell Research, vol.25, issue.3, pp.90192-90198, 1961. ,
MAPK11 in breast cancer cells enhances osteoclastogenesis and bone resorption, Biochimie, vol.106, pp.24-32, 2014. ,
,
Senescence in Health and Disease, Cell, vol.169, issue.6, pp.1000-1011, 2017. ,
Mechanism of radiation-induced bystander effects: a unifying model, Journal Of Pharmacy And Pharmacology, vol.60, issue.8, pp.943-950, 2008. ,
Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a, Molecular Cell, vol.14, issue.4, pp.501-513, 2004. ,
Distinct DNA methylomes of newborns and centenarians, Proceedings Of The National Academy Of Sciences, vol.109, issue.26, pp.10522-10527, 2012. ,
,
The p38, 2006. ,
Colonization in Human Ovarian Carcinoma, Cancer Research, vol.66, issue.4, pp.2264-2270 ,
, , 2012.
, Granzyme B in injury, inflammation and repair, Trends Mol Med, vol.12, pp.732-741
Tumor Recovery by Angiogenic Switch from Sprouting to Intussusceptive Angiogenesis after Treatment with PTK787/ZK222584 or Ionizing Radiation, The American Journal Of Pathology, vol.173, issue.4, pp.1173-1185, 2008. ,
,
Transmitting senescence to the cell neighbourhood, Nature Cell Biology, vol.15, issue.8, pp.887-889, 2013. ,
NOTCH1 mediates a switch between two distinct secretomes during senescence, Nature Cell Biology, vol.18, issue.9, pp.979-992, 2016. ,
,
, Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-?, and Bcl-2, 2007.
, Molecular Cell, vol.25, issue.2, pp.193-205
Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy, Nature Medicine, vol.17, issue.7, pp.860-866, 2011. ,
,
Biological Interaction Between Lymphocytes and, Other Cells. British Journal Of Haematology, vol.2, issue.3, pp.283-294, 1956. ,
Maturation of autophagosomes and endosomes : a key role for Rab7, Biochim Biophys Acta, vol.1833, issue.3, pp.503-513, 2013. ,
Lack of p53 function promotes radiation-induced mitotic catastrophe in mouse embryonic fibroblast cells, Cancer Cell International, vol.6, issue.1, p.11, 2006. ,
The Stress Kinase p38? as a Target for Cancer Therapy, Cancer Res, 2015. ,
, , pp.3997-4002
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies, Leukemia, vol.23, issue.6, pp.1139-1151, 2009. ,
Lysosomemediated processing of chromatin in senescence, The Journal Of Cell Biology, vol.202, issue.1, pp.129-143, 2013. ,
,
Programmed Cell Death in Animal Development, Cell, vol.88, issue.3, pp.347-354, 1997. ,
An overview on "cellular cannibalism" with special reference to oral squamous cell carcinoma, Experimental Oncology, vol.37, issue.4, pp.242-245, 2015. ,
Manipulation of apoptosis in the host-parasite interaction, Trends In Parasitology, vol.20, issue.6, pp.280-287, 2004. ,
Founder BRCA1/2 mutations in the Europe: implications for hereditary breast-ovarian cancer prevention and control, EPMA Journal, vol.1, issue.3, pp.397-412, 2010. ,
, , 2011.
, Emperipolesis and cell death in NOD2-related Blau Syndrome and Crohn's disease, Pediatric Rheumatology, vol.9, p.293
Cardiac Metastasis in Lymphoma and Leukemia, Diseases Of The Chest, vol.52, issue.4, pp.481-484, 1967. ,
, p38 MAPK, Microglial Signaling, and Neuropathic Pain, vol.3, pp.1744-8069, 2007.
Characterization of the Structure and Function of a New Mitogen-activated Protein Kinase (p38?), Journal Of Biological Chemistry, vol.271, issue.30, pp.17920-17926, 1996. ,
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis, Advances In Cancer Research, pp.19-65, 2009. ,
Autophagy and human diseases, Cell Research, vol.24, issue.1, pp.69-79, 2013. ,
,
LC3-and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells, Methods, vol.75, pp.13-18, 2015. ,
, Nature, issue.6832, pp.1111-1116, 2001.
Evaluation of cannibalistic cells: a novel entity in prediction of aggressive nature of oral squamous cell carcinoma, Acta Odontologica Scandinavica, vol.72, issue.6, pp.418-423, 2014. ,
Microenvironmental regulation of metastasis, Nature Reviews Cancer, vol.9, issue.4, pp.239-252, 2008. ,
mTOR regulation of autophagy, FEBS Letters, vol.584, issue.7, pp.1287-1295, 2010. ,
Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance, Immunity, vol.38, issue.2, pp.209-223, 2013. ,
,
Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL, Journal Of Biological Chemistry, vol.288, issue.43, pp.31268-31279, 2013. ,
,
Cellular cannibalism: A promising feature to determine cancer prognosis, Journal Of Oral Research And Review, vol.8, issue.1, p.45, 2016. ,
BCL-2 family proteins: changing partners in the dance towards death, Cell Death And Differentiation, vol.25, issue.1, pp.65-80, 2017. ,
Role of Rho/ROCK and p38 MAP Kinase Pathways in Transforming Growth Factor-?-mediated Smad-dependent Growth Inhibition of Human Breast Carcinoma Cellsin Vivo, Journal Of Biological Chemistry, vol.280, issue.2, pp.1024-1036, 2004. ,
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4, Science, vol.349, issue.6255, pp.5612-5612, 2015. ,
The Beclin 1 network regulates autophagy and apoptosis, Cell Death & Differentiation, vol.18, issue.4, pp.571-580, 2011. ,
Autophagy at the crossroads of catabolism and anabolism, Nature Reviews Molecular Cell Biology, vol.16, issue.8, pp.461-472, 2015. ,
Radiation-induced effects and the immune system in cancer, Frontiers In Oncology, vol.2, 2012. ,
Chaperone-mediated autophagy: a unique way to enter the lysosome world, Trends In Cell Biology, vol.22, issue.8, pp.407-417, 2012. ,
Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling Pathways, Molecular And Cellular Biology, vol.25, issue.7, pp.2733-2743, 2005. ,
,
The Essential Role of Evasion from Cell Death in Cancer, Advances In Cancer Research, pp.39-96, 2011. ,
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics, British Journal Of Cancer, vol.26, issue.4, pp.239-257, 1972. ,
,
Autophagy-Dependent Secretion: Contribution to Tumor Progression, Frontiers In Oncology, vol.6, 2016. ,
Protein phosphatases and the regulation of mitogen-activated protein kinase signalling, 2000. ,
, Current Opinion In Cell Biology, vol.12, issue.2, pp.75-82
Pathological roles of MAPK signaling pathways in human diseases, Biochimica Et Biophysica Acta (BBA) -Molecular Basis Of Disease, vol.1802, issue.4, pp.396-405, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-00566733
,
p38 MAPK Autophosphorylation Drives Macrophage IL-12 Production during Intracellular Infection, The Journal Of Immunology, vol.174, issue.7, pp.4178-4184, 2005. ,
Cancer immunoediting from immune surveillance to immune escape, Immunology, vol.121, issue.1, pp.1-14, 2007. ,
Role of VHL Gene Mutation in Human Cancer, Journal Of Clinical Oncology, vol.22, issue.24, pp.4991-5004, 2004. ,
The Regulation of INK4/ARF in Cancer and Aging, Cell, vol.127, issue.2, pp.265-275, 2006. ,
Senescent tumor cells lead the collective invasion in thyroid cancer, Nature Communications, vol.8, 2017. ,
Mechanical stress meets autophagy: potential implications for physiology and pathology, 2012. ,
, Trends In Molecular Medicine, vol.18, issue.10, pp.583-588
?-Synuclein activates stress signaling protein kinases in THP-1 cells and microglia, Neurobiology Of Aging, vol.29, issue.5, pp.739-752, 2008. ,
Atg" is an abbreviation for "autophagy-related, Autophagy, vol.8, issue.9, pp.1281-1282, 2012. ,
Endogenous DNA Damage and Repair Enzymes, Proteomics & Bioinformatics, vol.14, issue.3, pp.122-125, 2016. ,
Alcohol consumption and cigarette smoking in combination: A predictor of contralateral breast cancer risk in the WECARE study, International Journal Of Cancer, vol.141, issue.5, pp.916-924, 2017. ,
Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling, Cell Death & Differentiation, vol.21, issue.1, pp.92-99, 2013. ,
A Time to Kill: Targeting Apoptosis in Cancer, International Journal Of Molecular Sciences, vol.16, issue.2, pp.2942-2955, 2015. ,
Clinical Significance of "Cannibalism" in Urinary Cytology of Bladder Cancer, Acta Cytologica, vol.42, issue.6, pp.1365-1369, 1998. ,
Radiation and ceramide-induced apoptosis, Oncogene, vol.22, pp.5897-5906, 2003. ,
Loss of autophagy in the central nervous system causes neurodegeneration in mice, Nature, issue.7095, pp.880-884, 2006. ,
,
Regulation of MAP kinases by MAP kinase phosphatases, Biochimica Et Biophysica Acta (BBA) -Molecular Cell Research, vol.1773, issue.8, pp.1227-1237, 2007. ,
,
Physiological roles of mitogenactivated-protein-kinase-activated p38-regulated/activated protein kinase, World Journal Of Biological Chemistry, vol.2, issue.5, p.73, 2011. ,
Role of p38 MAP Kinase Signal Transduction in Solid Tumors, Genes & Cancer, vol.4, issue.9, pp.342-359, 2013. ,
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation, Cell Death Differ, vol.14, issue.2, pp.230-239, 2007. ,
A non-genetic route to aneuploidy in human cancers, Nature Cell Biology, vol.13, issue.3, pp.324-330, 2011. ,
Mechanisms and consequences of entosis, Cellular And Molecular Life Sciences, vol.73, pp.2379-2386, 2016. ,
Involvement of p38-ßTrCP-Tristetraprolin-TNF? axis in radiation pneumonitis, Oncotarget, vol.8, issue.29, 2017. ,
,
Lysosomes and autophagy in cell death control, Nature Reviews Cancer, vol.5, issue.11, pp.886-897, 2005. ,
,
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death, Cell Death And Differentiation, vol.16, issue.1, pp.3-11, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00407686
, , 2005.
, Classification of cell death: recommendations of the Nomenclature Committee on Cell Death, Cell Death And Differentiation, vol.12, pp.1463-1467
Mitochondrial Membrane Permeabilization in Cell Death, Physiological Reviews, vol.87, issue.1, pp.99-163, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-00172652
Autophagic cell death : the story of a misnomer, Nat Rev Mol Cell Biol, issue.12, pp.1004-1010, 2008. ,
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging, Proceedings Of The National Academy Of Sciences, vol.98, issue.21, pp.12072-12077, 2001. ,
, , 2006.
, Macrophages use different internalization mechanisms to clear apoptotic and necrotic cells, Cell Death And Differentiation, vol.13, issue.12, pp.2011-2022
Many faces of DAMPs in cancer therapy, Cell Death & Disease, vol.4, issue.5, pp.631-631, 2013. ,
Body Mass Index and Adenocarcinomas of the Esophagus or Gastric Cardia: A Systematic Review and Meta-analysis, Cancer Epidemiology Biomarkers & Prevention, vol.15, issue.5, pp.872-878, 2006. ,
,
, , 2008.
, Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network, Cell, vol.133, issue.6, pp.1019-1031
Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta, Biochemical Journal, vol.379, issue.1, pp.133-139, 2004. ,
,
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase, Biochem Biophys Res Commun, vol.263, pp.825-831, 1999. ,
Caspase function in programmed cell death, Cell Death And Differentiation, vol.14, issue.1, pp.32-43, 2006. ,
The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment, Trends In Immunology, vol.37, issue.3, pp.208-220, 2016. ,
,
, , 2012.
, Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis, Blood, vol.120, issue.19, pp.4058-4067
Silent Cleanup of Very Early Apoptotic Cells by Macrophages, The Journal Of Immunology, vol.171, issue.9, pp.4672-4679, 2003. ,
p38? and p38? Mediate Oncogenic rasinduced Senescence through Differential Mechanisms, Journal Of Biological Chemistry, vol.284, issue.17, pp.11237-11246, 2009. ,
Molecular exploitation of apoptosis pathways in prostate cancer, 2011. ,
, , 2008.
, GATA-4 Regulates Bcl-2 Expression in Ovarian Granulosa Cell Tumors, Endocrinology, vol.149, issue.11, pp.5635-5642
MTOR regulates the protumorigenic senescence-associated secretory phenotype by promoting IL1A translation, Nature Cell Biology, vol.17, issue.8, pp.1049-1061, 2015. ,
How cell death shapes cancer, Cell Death And Disease, vol.6, issue.3, 2015. ,
, , 2014.
, MR guidance in radiotherapy, Physics In Medicine And Biology, vol.59, issue.21, pp.349-369
,
Silencing the Metallothionein-2A Gene Induces Entosis in Adherent MCF-7 Breast Cancer Cells. The Anatomical Record, Advances In Integrative Anatomy And Evolutionary Biology, vol.293, issue.10, pp.1685-1691, 2010. ,
Alice in caspase land. A phylogenetic analysis of caspases from worm to man, Cell Death And Differentiation, vol.9, issue.4, pp.358-361, 2002. ,
,
) p53, guardian of the genome, Nature, vol.358, pp.15-16, 1992. ,
Dying cell clearance and its impact on the outcome of tumor radiotherapy, Frontiers In Oncology, vol.2, 2012. ,
Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth, Journal Of Cellular And Molecular Medicine, vol.6, issue.1, pp.1-12, 2002. ,
Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research, Carcinogenesis, vol.16, issue.1, pp.39-52, 1995. ,
,
Commitment Point during G0->G1 That Controls Entry into the Cell Cycle, Molecular And Cellular Biology, vol.23, issue.7, pp.2351-2361, 2003. ,
,
Context-dependent effects of cellular senescence in cancer development, British Journal of Cancer, vol.114, pp.1180-1184, 2016. ,
Senescence-associated ?galactosidase is lysosomal ?-galactosidase, Aging Cell, vol.5, issue.2, pp.187-195, 2006. ,
Human retinoblastoma susceptibility gene: cloning, identification, and sequence, Science, vol.235, issue.4794, pp.1394-1399, 1987. ,
,
Emperipolesis of Hematopoietic Cells within Megakaryocytes in Bone Marrow of the Rat, Veterinary Pathology, vol.26, issue.6, pp.473-478, 1989. ,
Constitutive activity and differential localization of p38? and p38ß MAPKs in adult mouse brain, Journal Of Neuroscience Research, vol.60, issue.5, pp.623-631, 2000. ,
,
Unveiling the roles of autophagy in innate and adaptive immunity, Nature Reviews Immunology, vol.7, issue.10, pp.767-777, 2007. ,
Autophagy in the Pathogenesis of Disease, Cell, vol.132, issue.1, pp.27-42, 2008. ,
,
The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer, The Journal Of Experimental Medicine, 2018. ,
,
Identification of Pancreatic Cancer Stem Cells, Cancer Research, vol.67, issue.3, pp.1030-1037, 2007. ,
Endonuclease G is an apoptotic DNase when released from mitochondria, Nature, issue.6842, pp.95-99, 2001. ,
Caspase-9: structure, mechanisms and clinical application, Oncotarget, vol.8, issue.14, 2017. ,
Microautophagy: lesser-known self-eating, Cellular And Molecular Life Sciences, vol.69, issue.7, pp.1125-1136, 2011. ,
Entosis Allows Timely Elimination of the Luminal Epithelial Barrier for Embryo Implantation, Cell Reports, vol.11, issue.3, pp.358-365, 2015. ,
A Review of Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer, International Journal Of Biological Sciences, vol.12, issue.8, pp.1022-1031, 2016. ,
Radiation-induced tumor dormancy reflects an equilibrium between the proliferation and T lymphocyte-mediated death of malignant cells, 2013. ,
, e25668, vol.2
Induction of autophagy and inhibition of tumorigenesis by beclin 1, Nature, vol.402, issue.6762, pp.672-676, 1999. ,
,
, , 2014.
, Serum-dependent processing of late apoptotic cells for enhanced efferocytosis, Cell Death & Disease, vol.5, issue.5, pp.1264-1264
The Warburg Effect: How Does it Benefit Cancer Cells?, Trends In Biochemical Sciences, vol.41, issue.3, pp.211-218, 2016. ,
Granzyme A activates another way to die, Immunological Reviews, vol.235, issue.1, pp.93-104, 2010. ,
,
Role of the p16 tumor suppressor gene in cancer, Journal Of Clinical Oncology, vol.16, issue.3, pp.1197-1206, 1998. ,
Macrophages Regulate the Angiogenic Switch in a Mouse Model of Breast Cancer, Cancer Research, vol.66, issue.23, pp.11238-11246, 2006. ,
,
Cancer risks associated with external radiation from diagnostic imaging procedures, CA: A Cancer Journal For Clinicians, vol.62, issue.2, pp.75-100, 2012. ,
, Necroptosis. New England Journal Of Medicine, vol.370, issue.5, pp.455-465, 2014.
,
Reactive oxygen species in cancer, Free Radical Research, vol.44, issue.5, pp.479-496, 2010. ,
The p38 MAPK stress pathway as a tumor suppressor or more?, Frontiers In Bioscience, issue.13, p.3581, 2008. ,
Emperipolesis in a case of B-cell lymphoma: a rare phenomenon outside of Rosai-Dorfman disease, Annals Of Diagnostic Pathology, vol.7, issue.5, pp.310-313, 2003. ,
Cancer Cell Cannibalism: A Primeval Option to Survive, Current Molecular Medicine, vol.15, issue.9, pp.836-841, 2015. ,
Necroptotic signaling in adaptive and innate immunity, Seminars In Cell & Developmental Biology, vol.35, pp.33-39, 2014. ,
, Potent Phagocytic Activity Discriminates Metastatic and Primary Human Malignant Melanomas: A Key Role of, 2003.
, Laboratory Investigation, vol.83, issue.11, pp.1555-1567
Cannibalism of Live Lymphocytes by Human Metastatic but Not Primary Melanoma Cells, Cancer Research, vol.66, issue.7, pp.3629-3638, 2006. ,
The CASBAH: a searchable database of caspase substrates, Cell Death And Differentiation, vol.14, issue.4, pp.641-650, 2007. ,
Mitochondria-dependent andindependent Regulation of Granzyme B-induced Apoptosis, The Journal Of Experimental Medicine, vol.189, issue.1, pp.131-144, 1999. ,
Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype, Experimental Gerontology, vol.82, pp.39-49, 2016. ,
,
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases, Immunological Reviews, vol.277, issue.1, pp.61-75, 2017. ,
,
MAPKAP Kinase-2 Is a Cell Cycle Checkpoint Kinase that Regulates the G2/M Transition and S Phase Progression in Response to UV Irradiation, Molecular Cell, vol.17, issue.1, pp.37-48, 2005. ,
Whole chromosome instability resulting from the synergistic effects of pRB and p53 inactivation, Oncogene, vol.33, issue.19, pp.2487-2494, 2013. ,
The Protein Kinase Complement of the Human Genome, Science, vol.298, issue.5600, pp.1912-1934, 2002. ,
Evolution of protein kinase signaling from yeast to man, Trends In Biochemical Sciences, vol.27, issue.10, pp.2179-2184, 2002. ,
Combination of Ionising Irradiation and Hyperthermia Activates Programmed Apoptotic and Necrotic Cell Death Pathways in Human Colorectal Carcinoma Cells, Strahlentherapie Und Onkologie, vol.186, issue.11, pp.587-599, 2010. ,
,
, , 2009.
, Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms. Mini-Reviews In Medicinal Chemistry, vol.9, issue.9, pp.1084-1101
,
Mechanisms of apoptotic phosphatidylserine exposure, Cell Research, vol.23, issue.11, pp.1247-1248, 2013. ,
, , 1995.
, Non-erythroid Spectrin) during Apoptosis. Journal Of Biological Chemistry, vol.270, issue.12, pp.6425-6428
Surfaceexposed calreticulin in the interaction between dying cells and phagocytes, Annals Of The New York Academy Of Sciences, vol.1209, issue.1, pp.77-82, 2010. ,
Entosis: The emerging face of non-cell-autonomous type IV programmed death, Biomedical Journal, vol.40, issue.3, pp.133-140, 2017. ,
,
Granzyme A Cleaves a Mitochondrial Complex I Protein to Initiate Caspase-Independent Cell Death, Cell, vol.133, issue.4, pp.681-692, 2008. ,
,
TGF? in Cancer, Cell, vol.134, issue.2, pp.215-230, 2008. ,
Targeting the Mitotic Catastrophe Signaling Pathway in Cancer, Mediators Of Inflammation, pp.1-13, 2015. ,
Cell biology: Microtubule catastrophe, Nature, issue.5991, pp.196-197, 1984. ,
,
Second Neoplasms in Survivors of Childhood Cancer: Findings From the Childhood Cancer Survivor Study Cohort, Journal Of Clinical Oncology, vol.27, issue.14, pp.2356-2362, 2009. ,
, AMP-Activated Protein Kinase and Autophagy. Autophagy, vol.3, issue.3, pp.238-240, 2007.
, , 2006.
, AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis, Journal Of Biological Chemistry, vol.281, issue.46, pp.34870-34879
p73, the "Assistant" Guardian of the Genome?, Annals Of The New York Academy Of Sciences, vol.1010, issue.1, pp.9-15, 2003. ,
Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy, Oncotarget, issue.35, p.7, 2016. ,
,
SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases, FEBS Letters, vol.383, issue.3, pp.273-276, 1996. ,
, NETosis. Autoimmune Diseases, pp.1-7, 2013.
,
Human Viral Oncogenesis: A Cancer Hallmarks Analysis, 2014. ,
, Cell Host & Microbe, vol.15, issue.3, pp.266-282
Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis, Oncotarget, vol.8, issue.37, 2017. ,
Salmonella and Caspase-1: A complex Interplay of Detection and Evasion, 2011. ,
, Frontiers In Microbiology, vol.2
Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum, Autophagy, vol.7, issue.7, pp.673-682, 2011. ,
Mitosis: a history of division, Nature Cell Biology, vol.3, issue.1, pp.17-21, 2001. ,
,
Autophagy in mammalian development and differentiation, Nature Cell Biology, vol.12, issue.9, pp.823-830, 2010. ,
NK and NKT cell functions in immunosenescence, Aging Cell, vol.3, issue.4, pp.177-184, 2004. ,
Synergy of Radiotherapy and a Cancer Vaccine for the Treatment of HPV-Associated Head and Neck Cancer, 2015. ,
, Molecular Cancer Therapeutics, vol.14, issue.6, pp.1336-1345
Impact of stress on cancer metastasis, Future Oncology, vol.6, issue.12, pp.1863-1881, 2010. ,
Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death, Cell Death And Disease, vol.6, issue.2, 2015. ,
Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells, Molecular Cancer Therapeutics, vol.4, issue.10, pp.1495-1504, 2005. ,
,
Induction of autophagy by amino-acid deprivation in perfused rat liver, Nature, vol.270, issue.5633, pp.174-176, 1977. ,
Autophagy in cancer metastasis, Oncogene, vol.36, issue.12, pp.1619-1630, 2016. ,
Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis, Proceedings Of The National Academy Of Sciences, vol.97, issue.19, pp.10454-10459, 2000. ,
Cellular senescence: from physiology to pathology, Nature Reviews Molecular Cell Biology, vol.15, issue.7, pp.482-496, 2014. ,
Programmed Cell Senescence during Mammalian Embryonic Development, Cell, vol.155, issue.5, pp.1104-1118, 2013. ,
The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy, Hypoxia, 83, 2015. ,
Phagocytosis and Killing of Bacteria by Professional Phagocytes and Dendritic Cells, Clinical And Vaccine Immunology, vol.9, issue.6, pp.1165-1168, 2002. ,
Highly penetrant hereditary cancer syndromes, Oncogene, vol.23, issue.38, pp.6445-6470, 2004. ,
Necroptosis and Cancer, Trends In Cancer, vol.3, issue.4, pp.294-301, 2017. ,
,
, Nature Genetics, vol.25, issue.2, pp.177-181, 2000.
Cellular senescence and chromatin organisation, British Journal Of Cancer, vol.96, issue.5, pp.686-691, 2007. ,
p38 MAPK signaling during murine preimplantation development, Developmental Biology, vol.268, issue.1, pp.76-88, 2004. ,
,
Bone cancer rates in dinosaurs compared with modern vertebrates, Transactions Of The Kansas Academy Of Science, issue.3, pp.155-158, 2007. ,
,
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance, Nature, vol.455, issue.7211, pp.396-400, 2008. ,
,
PRAK, a novel protein kinase regulated by the p38 MAP kinase, The EMBO Journal, vol.17, issue.12, pp.3372-3384, 1998. ,
In-cell infection: a novel pathway for Epstein-Barr virus infection mediated by cell-in-cell structures, Cell Research, vol.25, issue.7, pp.785-800, 2015. ,
,
, , 2011.
, Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth, Nature Medicine, vol.17, issue.11, pp.1498-1503
Angiogenesis in cancer, Vascular Health And Risk Management, vol.2, issue.3, pp.213-219, 2006. ,
Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study, Journal Of Neuropathology & Experimental Neurology, vol.64, issue.2, pp.113-122, 2005. ,
Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis, Proceedings Of The National Academy Of Sciences, vol.103, issue.33, pp.12493-12498, 2006. ,
p38?MAPK: Emerging Roles of a Neglected Isoform, International Journal Of Cell Biology, pp.1-12, 2014. ,
Caspase 8 inhibits programmed necrosis by processing CYLD, Nature Cell Biology, vol.13, issue.12, pp.1437-1442, 2011. ,
,
Crosstalk in NF-?B signaling pathways, Nat. Immunol, vol.12, pp.695-708, 2011. ,
, , 2014.
, Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
, Cell Death & Differentiation, vol.21, issue.6, pp.998-1012
Cannibalism' (cell phagocytosis) does not differentiate reactive renal tubular cells from urothelial carcinoma cells, 2009. ,
, Cytopathology, vol.20, issue.4, pp.224-230
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence, Nature, vol.409, issue.6823, pp.1067-1070, 2001. ,
,
Caspase-mediated crosstalk between autophagy and apoptosis: Mutual adjustment or matter of dominance, Journal Of Cancer Research And Therapeutics, vol.11, issue.3, 2015. ,
Investigation of Pericytes, Hypoxia, and Vascularity in Bladder Tumors: Association With Clinical Outcomes, Oncology Research Featuring Preclinical And Clinical Cancer Therapeutics, vol.17, issue.3, pp.93-101, 2008. ,
,
The p38 signal transduction pathway activation and function, Cellular Signalling, vol.12, issue.1, pp.71-77, 2000. ,
Anti-C1q antibodies in systemic lupus erythematosus, Lupus, vol.24, issue.1, pp.42-49, 2014. ,
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion, Cell, vol.121, issue.3, pp.335-348, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-02683498
,
Cell surface-bound IL-1 is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network, Proceedings Of The National Academy Of Sciences, vol.106, issue.40, pp.17031-17036, 2009. ,
Regulation of cell death: the calcium-apoptosis link, Nature Reviews Molecular Cell Biology, vol.4, issue.7, pp.552-565, 2003. ,
The CED-3/ICE-like Protease Mch2 Is Activated during Apoptosis and Cleaves the Death Substrate Lamin A, Journal Of Biological Chemistry, vol.271, issue.28, pp.16443-16446, 1996. ,
Prognostic significance of glutamine synthetase expression in unifocal advanced hepatocellular carcinoma, Journal Of Hepatology, vol.33, issue.2, pp.80365-80372, 2000. ,
Apoptosis and keratin intermediate filaments, Cell Death & Differentiation, vol.9, issue.5, pp.486-492, 2002. ,
Structure of the human ATG12-ATG5 conjugate required for LC3 lipidation in autophagy, Nat Struct Mol Biol, vol.20, issue.1, pp.59-66, 2013. ,
Senescent cell death brings hopes to life, Cell Cycle, vol.16, issue.1, pp.9-10, 2016. ,
,
The cell biology of cell-in-cell structures, Nature Reviews Molecular Cell Biology, vol.9, issue.10, pp.796-809, 2008. ,
, , 2007.
, Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion, Cell, vol.131, issue.5, pp.966-979
,
Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses, Aging, vol.8, issue.7, pp.1316-1329, 2016. ,
Hypoxia-induced autophagy in tumor cells: a key target for improving cancer immunotherapy, Cancer Cell & Microenvironment, 2014. ,
,
Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis, The Journal Of Cell Biology, vol.167, issue.3, pp.457-468, 2004. ,
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site, Nature Structural Biology, vol.9, issue.4, pp.268-272, 2002. ,
,
PD-1 Restrains Radiotherapy-Induced Abscopal Effect, Cancer Immunology Research, vol.3, issue.6, pp.610-619, 2015. ,
,
Myeloid-Derived Suppressor Cells, Advances In Cancer Research, pp.95-139, 2015. ,
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation, Journal Of Cell Science, vol.118, issue.3, pp.485-496, 2005. ,
,
Necroptosis and its role in inflammation, Nature, vol.517, issue.7534, pp.311-320, 2015. ,
The threedimensional structure of MAP kinase p38?: different features of the ATP-binding site in p38? compared with p38?, Acta Crystallographica Section D Biological Crystallography, vol.65, issue.8, pp.777-785, 2009. ,
,
The Cell-Cycle State of Stem Cells Determines Cell Fate Propensity, Cell, vol.155, issue.1, pp.135-147, 2013. ,
The Emerging Hallmarks of Cancer Metabolism, Cell Metabolism, vol.23, issue.1, pp.27-47, 2016. ,
Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression, Cancer Research, vol.72, issue.9, pp.2251-2261, 2012. ,
Cell death in development: shaping the embryo, 2006. ,
, Histochemistry And Cell Biology, vol.126, issue.2, pp.149-158
Activation-induced apoptosis of autoreactive and alloreactive T lymphocytes in the target organ as a major mechanism of tolerance, Immunology And Cell Biology, vol.77, issue.3, pp.216-223, 1999. ,
,
Stress-induced endocytosis and degradation of epidermal growth factor receptor are two independent processes, Cancer Cell International, issue.1, p.16, 2016. ,
Bacillus Calmette-Guérin (BCG) Infection Following Intravesical BCG Administration as Adjunctive Therapy For Bladder Cancer, Medicine, vol.93, issue.17, pp.236-254, 2014. ,
,
Adoptive T Cell Immunotherapy For Cancer, 2015. ,
, Rambam Maimonides Medical Journal, vol.6, issue.1
Autophagy: molecular machinery, regulation, and implications for renal pathophysiology, American Journal Of Physiology-Renal Physiology, vol.297, issue.2, pp.244-256, 2009. ,
Cancer as a chronic disease, Collegian, vol.17, issue.2, pp.47-50, 2010. ,
,
JIP4 is a PLK1 binding protein that regulates p38MAPK activity in G2 phase, Cellular Signalling, vol.27, issue.11, pp.2296-2303, 2015. ,
,
Naissance d'un fléau, 1992. ,
Xerostomia induced by radiotherapy: an overview of the physiopathology, clinical evidence, and management of the oral damage, Therapeutics And Clinical Risk Management, pp.171-188, 2015. ,
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer, Nature, vol.396, issue.6712, pp.699-703, 1998. ,
,
The p38 mitogen-activated protein kinase pathway and its role in interferon signaling, 2003. ,
, Pharmacology & Therapeutics, vol.98, issue.2, pp.129-142
The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation, Biochimica Et Biophysica Acta (BBA) -Molecular Cell Research, vol.1813, issue.9, pp.1619-1633, 2011. ,
Global burden of cancers attributable to infections in 2012: a synthetic analysis, The Lancet Global Health, vol.4, issue.9, pp.609-616, 2016. ,
, , pp.30143-30150
Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver, Proceedings Of The National Academy Of Sciences, vol.81, issue.14, pp.4270-4274, 1984. ,
,
Reactive oxygen species (ROS) and cancer: Role of antioxidative nutraceuticals, Cancer Letters, vol.387, pp.95-105, 2017. ,
Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells, Genes Dev, vol.14, issue.5, pp.574-584, 2000. ,
Senescence regulation by the p53 family, Methods Mol Biol, vol.965, pp.37-61, 2013. ,
Macrophage Diversity Enhances Tumor Progression and Metastasis, Cell, vol.141, issue.1, pp.39-51, 2010. ,
Prophylactic cranial irradiation in 399 patients with limited-stage small cell lung cancer, Oncology Letters, vol.11, issue.4, pp.2654-2660, 2016. ,
,
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene, Journal Of Clinical Investigation, vol.112, issue.12, pp.1809-1820, 2003. ,
Whole body radiotherapy: A TBI-guideline, Journal Of Medical Physics, vol.31, issue.1, 2006. ,
Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis, International Journal Of Hematology, vol.95, issue.1, pp.17-25, 2012. ,
,
Professional and non-professional phagocytes: an introduction, Trends In Cell Biology, vol.5, issue.3, pp.85-87, 1995. ,
Elevated levels of Rad51 recombination protein in tumor cells, Cancer Res, vol.1, issue.62, pp.219-225, 2002. ,
Emperipolesis -A Review, Journal of clinical and diagnostic research, 2014. ,
Cellular senescence and tumor suppressor gene p16, International Journal Of Cancer, vol.130, issue.8, pp.1715-1725, 2011. ,
Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways, J Biol Chem, vol.272, issue.5, pp.2753-61, 1997. ,
Mechanisms of apoptosis avoidance in cancer, Current Opinion In Oncology, vol.11, issue.1, p.68, 1999. ,
, , 2010.
, Differential activation of p38MAPK isoforms by MKK6 and MKK3, Cellular Signalling, vol.22, issue.4, pp.660-667
,
Crossing the endothelial barrier during metastasis, Nature Reviews Cancer, vol.13, issue.12, pp.858-870, 2013. ,
Intussusceptive microvascular growth in tumors, Cancer Letters, vol.316, issue.2, pp.126-131, 2012. ,
Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts, Oncogene, vol.16, issue.9, pp.1113-1123, 1998. ,
,
Four faces of cellular senescence, The Journal Of Cell Biology, vol.192, issue.4, pp.547-556, 2011. ,
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion, Nature Cell Biology, vol.11, issue.8, pp.973-979, 2009. ,
p38 MAPK Signaling in Osteoblast Differentiation, Frontiers In Cell And Developmental Biology, 2016. ,
Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation, 2012. ,
, EMBO J, vol.14, issue.22, pp.4304-4321
The role of autophagy in tumour development and cancer therapy, Expert Reviews In Molecular Medicine, vol.11, 2009. ,
The INK4 family of cell cycle inhibitors in cancer, Oncogene, vol.18, issue.38, pp.5311-5317, 1999. ,
,
,
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis, 2016. ,
, Nat Commun. Jun, vol.8, p.11762
cdc25+ functions as an inducer in the mitotic control of fission yeast, Cell, vol.45, issue.1, pp.90546-90551, 1986. ,
p38? regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP, The EMBO Journal, vol.24, issue.6, pp.1134-1145, 2005. ,
Megakaryocytic emperipolesis: A histological finding in myelodysplastic syndrome, Indian Journal Of Pathology And Microbiology, vol.52, issue.4, 2009. ,
The immune response to secondary necrotic cells, Apoptosis, vol.22, issue.10, pp.1189-1204, 2017. ,
Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1, FEBS Letters, vol.474, issue.2-3, pp.141-145, 2000. ,
,
Emerging role of NF-?B signaling in the induction of senescence-associated secretory phenotype (SASP), Cellular Signalling, vol.24, issue.4, pp.835-845, 2012. ,
,
Vascular Endothelial Growth Factors VEGF-B and VEGF-C Are Expressed in Human Tumors, The American Journal Of Pathology, vol.153, issue.1, pp.65550-65552, 1998. ,
Regulation of p73 by c-ABl through the p38 MAP kinase pathway, Oncogene, vol.21, pp.974-979, 2002. ,
Morphologic and biochemical hallmarks of apoptosis, Cardiovascular Research, vol.45, issue.3, pp.528-537, 2000. ,
Complex cannibalism: An unusual finding in oral squamous cell carcinoma, Oral Oncology, vol.48, issue.2, pp.4-6, 2012. ,
Cellular cannibalism in giant cells of central giant cell granuloma of jaw bones and giant cell tumors of long bones, Journal Of Investigative And Clinical Dentistry, vol.8, issue.2, 2016. ,
Neutrophil-tumor cell cannibalism in oral squamous cell carcinoma, Journal Of Oral Pathology & Medicine, vol.43, issue.6, pp.454-458, 2014. ,
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells, Stem Cell Research, vol.12, issue.1, pp.119-131, 2014. ,
Corpse clearance defines the meaning of cell death, Nature, issue.6805, pp.784-788, 2000. ,
Cell-in-cell structures are more potent predictors of outcome than senescence or apoptosis in head and neck squamous cell carcinomas, Radiation Oncology, issue.1, p.12, 2017. ,
The Biology of p38 Kinase : A central role in inflammation, Current Topics in Medicinal Chemistry, vol.5, issue.10, pp.921-928, 2005. ,
Ras and autophagy in cancer development and therapy, Oncotarget, vol.5, issue.3, 2014. ,
Sexual dysfunction and infertility as late effects of cancer treatment, European Journal Of Cancer Supplements, vol.12, issue.1, pp.41-53, 2014. ,
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization, Nature Reviews Molecular Cell Biology, vol.9, pp.655-662, 2008. ,
The morphology of various types of cell death in prenatal tissues, Teratology, issue.3, pp.253-66, 1973. ,
Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner, The Journal Of Experimental Medicine, vol.201, issue.3, pp.465-471, 2005. ,
Caspasemediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure, Science, vol.344, issue.6188, pp.1164-1168, 2014. ,
Old, new and emerging functions of caspases, Cell Death & Differentiation, vol.22, issue.4, pp.526-539, 2014. ,
Mechanisms of Action of Bcl-2 Family Proteins, Cold Spring Harbor Perspectives In Biology, vol.5, issue.4, pp.8714-008714, 2013. ,
,
Cell cannibalism and cancer, Diagnostic Cytopathology, 2010. ,
, Epigenetics in cancer, vol.31, issue.1, pp.27-36, 2009.
,
Role of Telomeres and Telomerase in Aging and Cancer, Cancer Discovery, vol.6, issue.6, pp.584-593, 2016. ,
,
Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen, Experimental Cell Research, vol.184, issue.1, pp.109-118, 1989. ,
, , pp.90369-90377
Cancer and Telomeres -An ALTernative to Telomerase, Science, vol.336, issue.6087, pp.1388-1390, 2012. ,
The RB and p53 pathways in cancer, Cancer Cell, vol.2, issue.2, pp.103-112, 2002. ,
, , pp.102-104
Oxytosis: A Novel Form of Programmed Cell Death, Current Topics In Medicinal Chemistry, vol.1, issue.6, pp.497-506, 2001. ,
,
Epigenetic Regulation of Cellular Senescence and Aging, Frontiers In Genetics, vol.8, 2017. ,
Suicidal emperipolesis: a process leading to cell-in-cell structures, T cell clearance and immune homeostasis, Current Molecular Medicine, vol.15, issue.9, pp.819-827, 2015. ,
Secondary necrosis: The natural outcome of the complete apoptotic program, FEBS Letters, vol.584, issue.22, pp.4491-4499, 2010. ,
Measurement of Phagocytosis and of the Phagosomal Environment in Polymorphonuclear Phagocytes by Flow Cytometry, Current Protocols In Cytometry, 2010. ,
,
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis, Nature Medicine, vol.7, issue.2, pp.192-198, 2001. ,
,
Prognostic Implications of Cell Cycle, Apoptosis, and Angiogenesis Biomarkers in Non-Small Cell Lung Cancer: A Review, Clinical Cancer Research, vol.11, issue.11, pp.3974-3986, 2005. ,
,
Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis, Plos ONE, vol.5, issue.6, 2010. ,
Inherited Pancreatic Cancer Syndromes, The Cancer Journal, vol.18, issue.6, pp.485-491, 2012. ,
Mitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways?, Journal Of Signal Transduction, pp.1-6, 2011. ,
Competing views on cancer, Journal Of Biosciences, vol.39, issue.2, pp.281-302, 2014. ,
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death, Cellular And Molecular Life Sciences, vol.71, issue.2, pp.331-348, 2013. ,
Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression, Plos ONE, vol.4, issue.4, 2009. ,
Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix, Cell Death & Differentiation, vol.11, issue.10, pp.1066-1075, 2004. ,
Extracellular pH changes activate the p38-MAPK signalling pathway in the amphibian heart, Journal Of Experimental Biology, vol.209, issue.7, pp.1344-1354, 2006. ,
,
Identification of the Cytolinker Plectin as a Major Early In Vivo Substrate for Caspase 8 during CD95-and Tumor Necrosis Factor Receptor-Mediated Apoptosis, Molecular And Cellular Biology, vol.20, issue.15, pp.5665-5679, 2000. ,
,
Ueber Carcinom-Einschlüsse, Archiv Für Pathologische Anatomie Und Physiologie Und Für Klinische Medicin, vol.126, issue.3, pp.533-541, 1891. ,
Cleavage and Shedding of E-cadherin after Induction of Apoptosis, Journal Of Biological Chemistry, vol.276, issue.7, pp.4972-4980, 2000. ,
, , 2014.
, Cooperation of Factor VII-Activating Protease and Serum DNase I in the Release of Nucleosomes From Necrotic Cells, Arthritis & Rheumatology, vol.66, issue.3, pp.686-693
Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention, Journal Of Clinical Investigation, vol.103, issue.9, pp.1237-1241, 1999. ,
Cancer prevention as part of precision medicine: 'plenty to be done, Carcinogenesis, vol.37, issue.1, pp.2-9, 2015. ,
,
A Plug Release Mechanism for, 2014. ,
, Membrane Permeation by MLKL. Structure, vol.22, issue.10, pp.1489-1500
Cancer therapy in the necroptosis era, Cell Death & Differentiation, vol.23, issue.5, pp.748-756, 2016. ,
p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents, Cancer Letters, vol.344, issue.2, pp.174-179, 2014. ,
PRAK is essential for ras-induced senescence and tumor suppression, Cell, vol.128, pp.295-308, 2007. ,
The Mitochondrial Basis of Aging, Molecular Cell, issue.5, pp.654-666, 2016. ,
,
Induction of entosis by epithelial cadherin expression, Cell Research, vol.24, issue.11, pp.1288-1298, 2014. ,
Cyclic CMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway, Science, vol.339, issue.6121, pp.786-91, 2013. ,
Competition between human cells by entosis, Cell Research, vol.24, issue.11, pp.1299-1310, 2014. ,
, Dose-painting » : mythe ou réalité, 2010.
, , vol.14, pp.554-562
Complement Is a Central Mediator of Radiotherapy-Induced Tumor-Specific Immunity and Clinical Response, Immunity, vol.42, issue.4, pp.767-777, 2015. ,
Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance, Trends In Pharmacological Sciences, vol.37, issue.7, pp.606-617, 2016. ,
Caspase-12 and ER-Stress-Mediated Apoptosis, Annals Of The New York Academy Of Sciences, vol.1010, issue.1, pp.186-194, 2003. ,
Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: The pivotal role of mitochondria, International Journal Of Radiation Biology, vol.91, issue.1, pp.1-12, 2014. ,
,
Tumorigenesis: it takes a village, Nature Reviews Cancer, vol.15, issue.8, pp.473-483, 2015. ,
, , 2005.
, Increased Intratumor V 24-Positive Natural Killer T Cells: A Prognostic Factor for Primary Colorectal Carcinomas, Clinical Cancer Research, vol.11, issue.20, pp.7322-7327
Senescent stroma promotes prostate cancer progression: the role of miR-210, Mol Oncol, vol.8, issue.8, pp.1729-1775, 2014. ,
Glutamine metabolism regulates autophagy-dependent mTORC1, 2017. ,
, reactivation during amino acid starvation, Nature Communications, vol.8, issue.1
Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis, EMBO Reports, vol.3, issue.8, pp.785-791, 2002. ,
, LC3 and Autophagy. Autophagosome And Phagosome, pp.77-88, 2008.
,
Diverse Mechanisms of Myocardial p38 Mitogen-Activated Protein Kinase Activation: Evidence for MKK-Independent Activation by a TAB1-Associated Mechanism Contributing to Injury During Myocardial Ischemia, Circulation Research, vol.93, issue.3, pp.254-261, 2003. ,
,
Regulation of autophagy by cytoplasmic p53, Nat Cell Biol, vol.10, issue.6, pp.676-87, 2008. ,
Senescent cells spread the word: non-cell autonomous propagation of cellular senescence, The EMBO Journal, vol.32, issue.14, pp.1975-1976, 2013. ,
, , 2016.
, BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance, Cancer Discovery, vol.6, issue.6, pp.612-629
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities, J Clin Invest, vol.123, issue.3, pp.966-72, 2013. ,
Mechanisms Involved in Radiation Enhancement of Intratumoral Dendritic Cell Therapy, Journal Of Immunotherapy, vol.31, issue.4, pp.345-358, 2008. ,
, , 2011.
Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs, Molecular Cell, vol.43, issue.3, pp.432-448 ,
Cyclin-Dependent Kinase 1-Mediated Bcl-xL, 2009. ,
, Phosphorylation Acts as a Functional Link Coupling Mitotic Arrest and Apoptosis, Molecular And Cellular Biology, vol.30, issue.3, pp.640-656
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases, Proceedings Of The National Academy Of Sciences, vol.110, issue.33, pp.3109-3118, 2013. ,
Past, present and future of radiotherapy for the benefit of patients, Nature Reviews Clinical Oncology, vol.10, issue.1, pp.52-60, 2012. ,
,
Nature, Nurture, and Cancer Risks: Genetic and Nutritional Contributions to Cancer, Annual Review Of Nutrition, vol.37, issue.1, pp.293-320, 2017. ,
,
MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation -relevance in a mouse model of Parkinson's disease, Journal Of Neurochemistry, vol.105, issue.5, pp.2039-2052, 2008. ,
,
Biologically adapted radiation therapy, Zeitschrift Für Medizinische Physik, 2017. ,
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6, EMBO J, vol.15, issue.24, pp.7026-7035, 1996. ,
p38 (MAPK) stress signalling in replicative senescence in fibroblasts from progeroid and genomic instability syndromes, Biogerontology, vol.14, issue.1, pp.47-62, 2013. ,
, , 2012.
, Inhibition of Apoptosis Signal-Regulating Kinase 1 Reduces Myocardial Ischemia-Reperfusion Injury in the
, Journal Of The American Heart Association, vol.1, issue.5, pp.0-0
Only three driver gene mutations are required for the development of lung and colorectal cancers, Proceedings Of The National Academy Of Sciences, vol.112, issue.1, pp.118-123, 2014. ,
Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis, Experimental Cell Research, vol.313, issue.16, pp.3635-3644, 2007. ,
,
Global cancer statistics, Cancer Journal For Clinicians, vol.65, issue.2, pp.87-108, 2012. ,
Cellular and molecular mechanisms of stressinduced premature senescence (SIPS) of human diploid fibroblasts and melanocytes, Experimental Gerontology, vol.35, issue.8, pp.180-187, 2000. ,
Functional significance of the perforin/granzyme cell death pathway, Nature Reviews Immunology, vol.2, issue.10, pp.735-747, 2002. ,
The Emerging Role of B Cells in Tumor Immunity, Cancer Research, vol.76, issue.19, pp.5597-5601, 2016. ,
Autophagy Is Essential for Preimplantation Development of Mouse Embryos, Science, vol.321, issue.5885, pp.117-120, 2008. ,
,
La nouvelle médecine du cancer, 2013. ,
Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock, Nature Cell Biology, vol.5, issue.12, pp.1104-1110, 2003. ,
Trial Watch: Immunotherapy plus radiation therapy for oncological indications, Oncoimmunology, vol.5, issue.9, 2016. ,
Cancer incidence and risk factors after solid organ transplantation, International Journal Of Cancer, vol.125, issue.8, pp.1747-1754, 2009. ,
Death through a tragedy: mitotic catastrophe, Cell Death & Differentiation, vol.15, issue.7, pp.1153-1162, 2008. ,
Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis, Cell, vol.156, issue.5, pp.1002-1016, 2014. ,
,
The cell-cell adhesion molecule E-cadherin, Cellular And Molecular Life Sciences, vol.65, issue.23, pp.3756-3788, 2008. ,
, , 2009.
necrosis and secondary necrosis converge on similar cellular disintegration features, Cell Death & Differentiation, vol.17, issue.6, pp.922-930 ,
Molecular mechanisms of necroptosis: an ordered cellular explosion, Nature Reviews Molecular Cell Biology, vol.11, issue.10, pp.700-714, 2010. ,
,
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation, Science, vol.324, issue.5930, pp.1029-1033, 2009. ,
,
Molecular Mechanisms and Pathophysiology of Necrotic Cell Death, Current Molecular Medicine, vol.8, issue.3, pp.207-220, 2008. ,
,
Myc Antagonizes Ras-mediated Growth, 2004. ,
, Journal Of Biological Chemistry, vol.280, issue.2, pp.1112-1122
Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-00474829
, Blood, vol.115, issue.2, pp.353-362
Integrins and cancer, Current Opinion In Cell Biology, vol.8, issue.5, pp.724-730, 1996. ,
, , pp.80115-80118
Mitotic catastrophe: a mechanism for avoiding genomic instability, Nature Reviews Molecular Cell Biology, vol.12, issue.6, pp.385-392, 2011. ,
,
Perforin-mediated target-cell death and immune homeostasis, Nature Reviews Immunology, vol.6, issue.12, pp.940-952, 2006. ,
Perforin and granzymes: function, dysfunction and human pathology, Nature Reviews Immunology, vol.15, issue.6, pp.388-400, 2015. ,
Biological effects and equivalent doses in radiotherapy: A software solution, Reports Of Practical Oncology & Radiotherapy, vol.19, issue.1, pp.47-55, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-00853583
,
Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death, Nature Reviews Molecular Cell Biology, vol.12, pp.439-452, 2011. ,
P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment, 2017. ,
, Oncogene, vol.36, issue.47, pp.6649-6657
Role for IGFBP7 in Senescence Induction by BRAF, Cell, vol.141, issue.5, pp.746-747, 2010. ,
protein expression correlates with radiation-induced apoptosis in the lack of p53 response to radiation therapy for cervical cancer, Int J Radiat Oncol Biol Phys, vol.70, issue.4, pp.1189-94, 2008. ,
Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: entosis without matrix detachment, Mol Biol Cell, vol.23, issue.11, pp.2076-2091, 2012. ,
DNA damage response and cellular senescence in tissues of aging mice, Aging Cell, vol.8, issue.3, pp.311-323, 2009. ,
,
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3, Molecular Cell, vol.54, issue.1, pp.133-146, 2014. ,
Simultaneous Degradation of ?II-and ?II-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells, Journal Of Biological Chemistry, vol.273, issue.35, pp.22490-22497, 1998. ,
Hepatitis C virus and autophagy, Biological Chemistry, issue.11, p.396, 2015. ,
,
Tumor dormancy: potential therapeutic target in tumor recurrence and metastasis prevention, Experimental Hematology & Oncology, vol.2, issue.1, p.29, 2013. ,
The Role of p38 MAPK in the Development of Diabetic Cardiomyopathy, International Journal Of Molecular Sciences, vol.17, issue.12, p.1037, 2016. ,
Cell-in-cell death is not restricted by caspase-3 deficiency in MCF-7 cells, J Breast Cancer, vol.19, issue.3, pp.231-241, 2009. ,
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death, Cell Research, vol.19, issue.12, pp.1350-1362, 2009. ,
,
Rapid reuptake of granzyme B leads to emperitosis: an apoptotic cell-in-cell death of immune killer cells inside tumor cells, Cell Death & Disease, vol.4, issue.10, pp.856-856, 2013. ,
cGAS is essential for the antitumor effect of immune checkpoint blockade, Proceedings Of The National Academy Of Sciences, vol.114, issue.7, pp.1637-1642, 2017. ,
The metabolism of tumors in the body, The Journal Of General Physiology, vol.8, issue.6, pp.519-530, 1927. ,
Molecular mechanisms of ionizing radiation-induced apoptosis, Immunology and Cell Biology, vol.77, pp.263-271, 1999. ,
JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy, Molecular Cell, vol.30, issue.6, pp.678-688, 2008. ,
,
Necroptosis in development, inflammation and disease, Nature Reviews Molecular Cell Biology, vol.18, issue.2, pp.127-136, 2016. ,
Retinoblastoma protein switches the E2F site from positive to negative element, Nature, vol.358, issue.6383, pp.259-261, 1992. ,
Androgen receptor enhances entosis, a nonapoptotic cell death, through modulation of Rho/ROCK pathway in prostate cancer cells, Prostate, vol.73, issue.12, pp.1306-1321, 2013. ,
, , 2011.
,
The Double-Edged Sword of Autophagy Modulation in Cancer, Clinical Cancer Research, vol.15, issue.17, pp.5308-5316, 2009. ,
Emerging Opportunities and Challenges in Cancer Immunotherapy, Clinical Cancer Research, vol.22, issue.8, pp.1845-1855, 2016. ,
,
Cytokine Stimulation Promotes Glucose Uptake via, 2007. ,
, Phosphatidylinositol-3 Kinase/Akt Regulation of Glut1 Activity and Trafficking, vol.18, pp.1437-1446
, , 2016.
, Dysfunction Induces Senescence with a Distinct Secretory Phenotype, Cell Metabolism, vol.23, issue.2, pp.303-314
,
, , 2007.
, Microbial Pathogen-Induced Necrotic Cell Death Mediated by the Inflammasome Components CIAS1/Cryopyrin/NLRP3 and ASC, vol.2, pp.147-159
,
Crystal Structure of p38 Mitogen-activated Protein Kinase, Journal Of Biological Chemistry, vol.271, issue.44, pp.27696-27700, 1996. ,
,
The physics of cancer: the role of physical interactions and mechanical forces in metastasis, Nature Reviews Cancer, vol.11, issue.7, pp.512-522, 2011. ,
,
Introduction to neoplasia, McMaster Pathophysiology Review. Pathophys.org. Retrieved, 2018. ,
Apoptosis in cancer: from pathogenesis to treatment, Journal Of Experimental & Clinical Cancer Research, vol.30, issue.1, 2011. ,
Nuclear Localization of p38 MAPK in Response to DNA Damage, International Journal Of Biological Sciences, pp.428-437, 2009. ,
,
Structural Comparison of p38 Inhibitor-Protein Complexes: A Review of Recent p38 Inhibitors Having Unique Binding Interactions, Current Topics In Medicinal Chemistry, vol.5, issue.10, pp.1005-1016, 2005. ,
NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy, Cell Death And Differentiation, vol.24, issue.9, pp.1632-1644, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-02356551
Caspases: A Molecular Switch Node in the Crosstalk between Autophagy and Apoptosis, International Journal Of Biological Sciences, vol.10, issue.9, pp.1072-1083, 2014. ,
p38 Mitogen-Activated Protein Kinase Controls a Switch Between Cardiomyocyte and Neuronal Commitment of Murine Embryonic Stem Cells by Activating Myocyte Enhancer Factor 2C-Dependent Bone Morphogenetic Protein 2, 2010. ,
, Transcription. Stem Cells And Development, vol.19, issue.11, pp.1723-1734
Early references to the mutational origin of cancer, International Journal of Epidemiology, vol.36, issue.1, pp.246-247, 2006. ,
Emperipolesis, entosis and beyond: Dance with fate, Cell Research, vol.18, issue.7, pp.705-707, 2008. ,
Aurora A orchestrates entosis by regulating a dynamic MCAK-TIP150 interaction, Journal Of Molecular Cell Biology, vol.6, issue.3, pp.240-254, 2014. ,
,
TRAF molecules in cell signaling and in human diseases, Journal Of Molecular Signaling, vol.8, 2013. ,
Ferroptosis: process and function, Cell Death & Differentiation, vol.23, issue.3, pp.369-379, 2016. ,
, The Transcriptional Repressor HBP1 Is a Target of the p38 Mitogen-Activated Protein Kinase Pathway in Cell Cycle Regulation, 2003.
, Molecular And Cellular Biology, vol.23, issue.23, pp.8890-8901
Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress, Cellular And Molecular Life Sciences, vol.71, issue.20, pp.3951-3967, 2014. ,
Prophylactic Cranial Irradiation in Small-Cell Lung Cancer, The Oncologist, vol.5, issue.4, pp.293-298, 2000. ,
cGAS is essential for cellular senescence, Proceedings Of The National Academy Of Sciences, vol.114, issue.23, pp.4612-4620, 2017. ,
,
Tumor vasculogenic mimicry predicts poor prognosis in cancer patients: a meta-analysis, Angiogenesis, vol.19, issue.2, pp.191-200, 2016. ,
,
Bcl-2 family proteins and cancer, Oncogene, vol.27, issue.50, pp.6398-6406, 2008. ,
,
p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling, 2017. ,
, The EMBO Journal, vol.36, issue.15, pp.2280-2295
Cancer Genetics and Epigenetics: Two Sides of the Same Coin, Cancer Cell, vol.22, pp.9-20, 2012. ,
The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity, European Journal Of Immunology, vol.40, issue.11, pp.2969-2975, 2010. ,
SASP reflects senescence, EMBO Reports, vol.10, issue.3, pp.228-230, 2009. ,
,
Termination of autophagy and reformation of lysosomes regulated by mTOR, Nature, vol.465, issue.7300, pp.942-946, 2010. ,
,
Fish consumption and risk of gastrointestinal cancers: A meta-analysis of cohort studies, World Journal Of Gastroenterology, vol.20, issue.41, p.15398, 2014. ,
,
Nutrient Sensing, Metabolism, and Cell Growth Control, Molecular Cell, vol.49, issue.3, pp.379-387, 2013. ,
Alternative cell death mechanisms in development and beyond, Genes & Development, vol.24, issue.23, pp.2592-2602, 2010. ,
Roles of Caspases in Necrotic Cell Death, Cell, vol.167, issue.7, pp.1693-1704, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01911306
Activation and signaling of the p38 MAP kinase pathway, Cell Research, vol.15, issue.1, pp.11-18, 2005. ,
Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1, Journal Of Biological Chemistry, vol.270, issue.41, pp.23934-23936, 1995. ,
Yin-yang effect of tumor infiltrating B cells in breast cancer: From mechanism to immunotherapy, Cancer Letters, vol.393, pp.1-7, 2017. ,
,
, p16INK4a Modulates p53 in Primary Human Mammary Epithelial Cells, vol.66, pp.10325-10331, 2006.
Role of necroptosis in the pathogenesis of solid organ injury, Cell Death & Disease, vol.6, issue.11, pp.1975-1975, 2015. ,
,
MNK1 expression increases during cellular senescence and modulates the subcellular localization of hnRNP A1, Experimental Cell Research, vol.318, issue.5, pp.500-508, 2012. ,
An experimental study of mummification pertinent to the antiquity of cancer, Cancer, vol.40, issue.3, pp.1358-1362, 1977. ,
Cancer and Aging -The Inflammatory Connection, Aging And Diseases, vol.8, issue.5, pp.611-627, 2017. ,
IL-17 Stimulates Differentiation of Human Anti-Inflammatory Macrophages and Phagocytosis of Apoptotic Neutrophils in Response to IL-10 and Glucocorticoids, The Journal Of Immunology, vol.190, issue.10, pp.5237-5246, 2013. ,