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La mémoire chez l’adolescent avec autisme : électrophysiologie, cognition et prise en charge

Abstract : Autism spectrum disorders (ASD) are neurodevelopmental disorders, characterized by difficulties in social communication with restricted and repetitive behaviors. ASD are associated with structural, functional and connectivity brain abnormalities that contribute to atypical cognitive functioning in this population. This work includes three projects aimed at characterizing the neurocognitive profile of ASD adolescents and young adults and proposing new rehabilitation programs. The first shows abnormal resting-state brain connectivity using electroencephalography that can account for the multimodal integration difficulties that directly impact introspection processes. The second project deepens the study of introspection processes in the context of autobiographical memory (ABM). The data collected confirm the ABM difficulties in ASD adolescents, with an atypical sensory profile, but also the existence of a positive effect of prompting and visual cues during recall. Beyond, our work highlights the importance of ABM rehabilitation, used as a key vector in social interactions. Then, the third project concerns the creation of an ABM rehabilitation program based on an individual and collective approach. Preliminary results show a beneficial effect on the social identity of adolescents with autism. ABM is, therefore, very relevant to study in autism, integrating a unique and ecological multimodal dimension, and an interesting tool of rehabilitation.
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Prany Wantzen. La mémoire chez l’adolescent avec autisme : électrophysiologie, cognition et prise en charge. Neurosciences. Université Paris sciences et lettres, 2019. Français. ⟨NNT : 2019PSLEP071⟩. ⟨tel-02873861⟩

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