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Lutte contre l'iatrogénie liée aux prescriptions d'hypnosédatifs chez le sujet âgé hospitalisé

Abstract : Few data exist regarding SHs initiation among hospitalized older patients, associated risk factors and efficiency of interventions promoting their good use. The objectives were (1) to determine the proportion of SH initiation in acute hospitalization units, the proportion of SH renewal at discharge and to study associated risk factors (SÉDATIF) and (2) to identify and assess regulatory and educational interventions designed to improve the appropriate use of SHs (HYPNOREV). In the retrospective multicenter study SÉDATIF, SH initiation occurred in 21.5% of patients 20 days after admission. SH renewal at discharge occurred in 38.7% of patients who had initiated it during their stay and were discharged home and in 56.0% of patients discharged to rehabilitation facilities. No risk factor could be highlighted. SH initiation after the first 6 days was associated with a lower risk of renewal in patients discharged to rehabilitation facilities (OR = 0.19, p = 0.02). Regarding the systematic review of the literature HYPNOREV (1980-2015): 31 studies assessing educational or regulatory interventions were included. Multi-faceted educational interventions reporting the involvement of healthcare professionals and patients and the spread of information through mass media were successful. Further better designed studies are needed to study this type of interventions in the hospital setting.
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Submitted on : Thursday, June 11, 2020 - 6:53:06 PM
Last modification on : Friday, August 21, 2020 - 6:54:29 AM


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  • HAL Id : tel-02865538, version 1


Elsa Bourcier. Lutte contre l'iatrogénie liée aux prescriptions d'hypnosédatifs chez le sujet âgé hospitalisé. Santé publique et épidémiologie. Sorbonne Université, 2018. Français. ⟨NNT : 2018SORUS383⟩. ⟨tel-02865538⟩



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