, Notre étude est la première étude évaluant l'intérêt d'une acquisition dynamique et du paramètre Ki pour le diagnostic différentiel HDU et TNE
Nous nous sommes donc intéressés à l'utilité d'une telle acquisition pour différencier l'HDU physiologique des TNE en imagerie 68 Ga-DOTATOC-TEP/TDM, qui est un piège diagnostique classique, Nos résultats montrent d'excellentes performances diagnostiques des paramètres statiques et dynamiques mais surtout des rapports TLR et TSR, 2013. ,
, 7% des patients présentaient une HDU pancréatique. Ces données sont légèrement inférieures aux chiffres de la littérature : 34,8% dans l'étude de Graybriel et al. en 68 Ga-DOTATATE-TEP/TDM, 3% dans l'étude de Krauz et al. en 68 Ga-DOTANOC-TEP/TDM [Krauz et al. 2012] et 70% dans l'étude de Jacobsson et al. en 68 Ga-DOTATOC-TEP/TDM, vol.25
, En approche SUV, nos résultats montrent que les paramètres statiques ont de bonnes
Nos résultats sont globalement concordants avec les données de la littérature ,
, les valeurs de SUVmax moyen dans les HDU et les TNE en
Aucun cut-off n'était proposé, SUVmax à 10.5±7.2 versus SUVmax médian à 13.62 dans les HDU et SUVmax à 63.2±52.0 versus SUVmax median à 53.99 dans les pTNE respectivement) ,
,
Avec le même traceur, il n'était en revanche pas retrouvé de cut-off avec des sensibilité et spécificité correctes par Krauz et al ,
, Prévalence et taux de malignité des ITf fixant au 18 FDG
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