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Analyse médico-économique de différentes stratégies de prévention dans les maladies neurodégénératives : application à la maladie d’Alzheimer et à la maladie de Parkinson

Abstract : In the current context of the growth of healthcare expenditures, health economics can help decision making in the process of resources allocation in the field of health. Neurodegenerative diseases (ND) are huge and costly diseases for which no cure is available to date. Prevention can be an axis of care of theses pathologies. It could help delay the disease progression or complications linked to these ones or to its treatments. In the frame of NDs, health economics can help to make choices in order to provide quality of healthcare to patients in the context of constraint resources. This thesis aimed to describe and analyze methodological characteristics of studies which assessed NDs costs, paying particular intention to informal costs. Our works revealed significant variations of methodological characteristics of a study to another. An additional effort must be performed by the scientific community in the field of methodological validation. This thesis also aimed to assess medical and economic consequences of prevention strategies in Alzheimer disease (AD) and Parkinson disease (PD). The observed results concerned the implementation of a directed prevention program in AD (I.e. multidomain intervention) and of a targeted prevention program in PD (i.e. therapeutic education). They confirmed the need to implement studies on prevention program on substantial time horizons
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Submitted on : Thursday, May 28, 2020 - 1:01:08 PM
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  • HAL Id : tel-02639863, version 1

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Nadège Costa. Analyse médico-économique de différentes stratégies de prévention dans les maladies neurodégénératives : application à la maladie d’Alzheimer et à la maladie de Parkinson. Santé. Université Claude Bernard - Lyon I, 2013. Français. ⟨NNT : 2013LYO10308⟩. ⟨tel-02639863⟩

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