, J. Am. Soc. Nephrol, p.4
, « Transplantation rénale : élargissement des critères de sélection des donneurs
,
« Outcomes of kidney transplants from non-heart-beating deceased donors as reported to the Japan Organ Transplant Network from, Clin. Transpl, pp.91-102, 1995. ,
« A good alternative to reduce the kidney shortage: kidneys from nonheartbeating donors, Transplantation, vol.65, issue.11, pp.1465-1470, 1998. ,
« The origin of the mammalian kidney: implications for recreating the kidney in vitro, vol.142, pp.1937-1947, 2015. ,
, « Renal physiology, 2011.
,
,
Human nephron number: implications for health and disease, Pediatr. Nephrol, vol.26, issue.9, pp.1529-1533, 2011. ,
Number and Function Are Influenced by Spontaneous and Induced Low Birth Weight in Rats, J. Am. Soc. Nephrol, vol.16, issue.10, pp.2913-2919, 2005. ,
« Nephron number and blood pressure in rat offspring with maternal high-protein diet, Pediatr. Nephrol, vol.17, pp.1000-1004, 2002. ,
, Effect of normal development on compensatory renal growth11Dedicated to our teacher in pediatrics, Prof. Rolf Zetterström,on his 60th anniversary, vol.18, pp.29-35, 1980.
, Research into the structure of the kidney glomerulus -making it count », Micron, vol.43, pp.1001-1009, 2012.
, Physiology of the Renal Interstitium, vol.10, pp.1831-1840, 2015.
« Phagocytosis of microparticles by alveolar macrophages during acute lung injury requires MerTK », Am. J. Physiol.-Lung Cell. Mol. Physiol, vol.314, issue.1, pp.69-82, 2018. ,
, Blood Pressure Changes Produced by Kidney Cross-Transplantation between Spontaneously Hypertensive Rats and Normotensive Rats, vol.47, pp.435-448, 1974.
« Kidneys from normotensive donors lower blood pressure in young transplanted spontaneously hypertensive rats », Am. J. Physiol, vol.273, issue.2, pp.175-180, 1997. ,
Physiologie humaine -Tout le cours en fiches, Dunod, 2016. ,
, The role of the kidney in regulating arterial blood pressure, vol.8, pp.602-609, 2012.
vasopressine et pression artérielle: importance de la concentration de l'urine et du rythme nycthéméral d'excrétion d'eau et de sodium, p.219 ,
ischémie reperfusion -Acteur essentiel du devenir du greffon rénal », médecine/sciences, vol.29, pp.183-188, 2013. ,
, Biomarqueurs dans l'insuffisance rénale aiguë
, Comparison of biomarkers in rat renal ischemiareperfusion injury, vol.8, pp.7577-7584, 2015.
Urdiales, « Monocyte chemoattractant protein-1: a key mediator in inflammatory processes », Int. J. Biochem. Cell Biol, vol.41, issue.5, pp.998-1001, 2009. ,
MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy, Am. J. Physiol. Renal Physiol, vol.294, issue.4, pp.697-701, 2008. ,
« Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury, J. Am. Soc. Nephrol. JASN, vol.14, issue.10, pp.2534-2543, 2003. ,
« Sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury, Ann. Intern. Med, vol.148, issue.11, pp.810-819, 2008. ,
« Ischémie reperfusion en transplantation rénale », EM-Consulte ,
,
« Oxidative stress as a common pathway to chronic tubulointerstitial injury in kidney allografts, Am. J. Physiol. Renal Physiol, vol.293, issue.2, pp.445-455, 2007. ,
« The relationship between inflammation and the anticoagulant pathway: the emerging role of endothelial nitric oxide synthase (eNOS) », Curr. Pharm. Des, vol.10, issue.8, pp.923-927, 2004. ,
« P53 Mediates the Apoptotic Response to GTP Depletion after Renal ,
Protective Role of a p53 Inhibitor, J. Am. Soc. Nephrol, vol.14, issue.1, pp.128-138, 2003. ,
A Review of Programmed Cell Death, Toxicol. Pathol, vol.35, issue.4, pp.495-516, 2007. ,
« Dissecting the "end game": clinical relevance, molecular mechanisms and laboratory assessment of apoptosis, Clin Invest Med, vol.27, issue.6, p.22, 2004. ,
, Apoptosis and acute kidney injury, vol.80, pp.29-40, 2011.
« Guanosine supplementation reduces apoptosis and protects renal function in the setting of ischemic injury, J. Clin. Invest, vol.108, issue.9, pp.1291-1298, 2001. ,
« Adenovirus-mediated bcl-2 gene transfer inhibits renal ischemia/reperfusion induced tubular oxidative stress and apoptosis », Am. J. Transplant. Off. J. Am. Soc. Transplant. Am. Soc. Transpl. Surg, vol.5, issue.6, pp.1194-1203, 2005. ,
« Podocyte-derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36, J. Extracell. Vesicles, vol.7, issue.1, 2018. ,
, Apoptosis and necrosis during ischaemia in renal tubular cells (LLC-PK1 and MDCK)
, Ren. Assoc, vol.13, issue.5, pp.1158-1167, 1998.
, Regulated necrosis in kidney ischemia-reperfusion injury, vol.96, pp.291-301, 2019.
« Ischemia and reperfusion-from mechanism to translation, Nat. Med, vol.17, issue.11, 2011. ,
« Ischemic acute renal failure: an inflammatory disease?, Kidney Int, vol.66, issue.2, pp.480-485, 2004. ,
, The immune system and kidney disease: basic concepts and clinical implications, vol.13, pp.738-753, 2013.
« Inflammatory cytokines in acute renal failure, Kidney Int, vol.66, pp.56-61, 2004. ,
« Maladaptive Role of IL-6 in Ischemic Acute Renal Failure, J. Am. Soc. Nephrol, vol.16, issue.11, pp.3315-3325, 2005. ,
« Plasma cytokine levels predict mortality in patients with acute renal failure, Kidney Int, vol.65, issue.4, pp.1357-1365, 2004. ,
« Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4, Kidney Int, vol.80, issue.5, pp.504-515, 2011. ,
« Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney, J. Clin. Invest, vol.115, issue.10, pp.2894-2903, 2005. ,
, Blood, Blood Components, Plasma, and Plasma Products, vol.37, pp.403-418, 2015.
« A Flow Cytometric Method for Determination of the Blood Neutrophil Fraction in Rats, J. Am. Assoc. Lab. Anim. Sci. JAALAS, vol.48, issue.2, pp.152-156, 2009. ,
« Partners in crime: neutrophils and monocytes/macrophages in inflammation and disease, Cell Tissue Res, vol.371, issue.3, p.551, 2018. ,
« Neutrophils in acute kidney injury: not neutral any more, Kidney Int, vol.75, issue.7, pp.674-676, 2009. ,
, Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury, vol.75, pp.689-698, 2009.
« Neutrophil extracellular traps: Is immunity the second function of chromatin?, J. Cell Biol, vol.198, issue.5, pp.773-783, 2012. ,
, La pêche miraculeuse des filets du neutrophile », médecine/sciences, vol.30, pp.544-549, 2014.
« Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI, J. Am. Soc. Nephrol. JASN, vol.28, issue.6, pp.1753-1768, 2017. ,
,
, « Neutrophil peptidyl arginine deiminase-4 has a pivotal role in ischemia/reperfusion-induced acute kidney injury, Kidney Int, vol.93, issue.2, pp.365-374, 2018.
« Peptidyl arginine deiminase-4 activation exacerbates kidney ischemiareperfusion injury », Am. J. Physiol. Renal Physiol, vol.307, issue.9, pp.1052-1062, 2014. ,
« Peptidyl arginine deiminase-4-deficient mice are protected against kidney and liver injury after renal ischemia and reperfusion », Am. J. Physiol. Renal Physiol, vol.311, issue.2, pp.437-449, 2016. ,
, Neutrophil extracellular traps in ischemic AKI: new way to kill, vol.93, pp.303-305, 2018.
, Macrophages in Renal Injury and Repair, vol.79, p.2017
« The Origins and Functions of Tissue-Resident Macrophages in Kidney Development, Front. Physiol, vol.8, 2017. ,
« Macrophage-mediated injury and repair after ischemic kidney injury, Pediatr. Nephrol. Berl. Ger, vol.30, issue.2, pp.199-209, 2015. ,
« The chemokine receptors CCR2 and CX3CR1 mediate ,
, monocyte/macrophage trafficking in kidney ischemia-reperfusion injury, vol.74, pp.1526-1537, 2008.
« CCR2 signaling contributes to ischemia-reperfusion injury in kidney, J. Am. Soc. Nephrol. JASN, vol.14, issue.10, pp.2503-2515, 2003. ,
, The regulation of inflammation by interferons and their STATs, vol.2, p.23820, 2013.
, Physiol. Rev, vol.87, issue.1, pp.315-424, 2007.
« Macrophage activation by endogenous danger signals, J. Pathol, vol.214, issue.2, pp.161-178, 2008. ,
« Transcriptional regulation of macrophage polarization: enabling diversity with identity, Nat. Rev. Immunol, vol.11, issue.11, pp.750-761, 2011. ,
« Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF », J. Clin. Invest, vol.101, issue.4, pp.890-898, 1998. ,
« Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages, J. Immunol. Baltim. Md, vol.185, issue.4, pp.2044-2050, 1950. ,
« Distinct macrophage phenotypes contribute to kidney injury and repair, J. Am. Soc. Nephrol. JASN, vol.22, issue.2, pp.317-326, 2011. ,
« Ischemia reperfusion induces IFN regulatory factor 4 in renal dendritic cells, which suppresses postischemic inflammation and prevents acute renal failure, J. Immunol. Baltim. Md, vol.185, issue.3, pp.1976-1983, 1950. ,
« p53 is renoprotective after ischemic kidney injury by reducing inflammation, J. Am. Soc. Nephrol. JASN, vol.24, issue.1, pp.113-124, 2013. ,
« The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2, Immunobiology, vol.223, issue.1, pp.101-111, 2018. ,
« Alternative activation of macrophages: an immunologic functional perspective », Annu. Rev. Immunol, vol.27, pp.451-483, 2009. ,
, Clin. Sci, vol.124, issue.7, pp.423-441, 2013.
« The many faces of endothelial microparticles, Arterioscler. Thromb. Vasc. Biol, vol.31, issue.1, pp.27-33, 2011. ,
« Red blood cell microparticles: clinical relevance », Transfus. Med. Hemotherapy Off. Organ Dtsch. Ges. Transfusionsmedizin Immunhamatologie, vol.39, issue.5, pp.342-347, 2012. ,
,
Shedding of procoagulant microparticles from unstimulated platelets by integrinmediated destabilization of actin cytoskeleton, FEBS Lett, vol.580, pp.5313-5320, 2006. ,
« Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts, Arterioscler. Thromb. Vasc. Biol, vol.31, issue.8, pp.1898-1907, 2011. ,
, Microparticles in kidney diseases: focus on kidney transplantation, vol.3, 2017.
« The majority of circulating plateletderived microparticles fail to bind annexin V, lack phospholipid-dependent procoagulant activity and demonstrate greater expression of glycoprotein Ib, Thromb. Haemost, vol.103, issue.5, pp.1044-1052, 2010. ,
« Circulating microparticles: square the circle, BMC Cell Biol, vol.14, p.23, 2013. ,
« Development and assessment of enzyme immunoassay for plateletderived microparticles, Thromb. Haemost, vol.85, issue.2, pp.326-330, 2001. ,
Exposure of platelet membrane phosphatidylserine regulates blood coagulation, Prog. Lipid Res, vol.42, issue.5, pp.423-438, 2003. ,
, Microparticles in hemostasis and thrombosis, vol.108, pp.1284-1297, 2011.
, Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes, vol.102, pp.2678-2683, 2003.
« PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of Fc?RI, Blood, vol.119, pp.5285-5293, 2012. ,
« Platelet microparticle membranes have 50-to 100-fold higher specific procoagulant activity than activated platelets, Thromb. Haemost, vol.97, issue.3, pp.425-434, 2007. ,
« Endothelium-derived microparticles impair endothelial function in vitro, Am. J. Physiol. Heart Circ. Physiol, vol.286, issue.5, pp.1910-1915, 2004. ,
« Circulating Microparticles Carry a Functional Endothelial Nitric Oxide Synthase That Is Decreased in Patients With Endothelial Dysfunction, J. Am. Heart Assoc ,
, Cardiovasc. Cerebrovasc. Dis, vol.2, issue.1, 2013.
« Endothelial microparticles prevent lipid-induced endothelial damage via Akt/eNOS signaling and reduced oxidative stress » ,
, Exp. Biol, vol.31, pp.4636-4648, 2017.
« Sonic hedgehog carried by microparticles corrects endothelial injury through nitric oxide release », FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol, vol.21, issue.11, pp.2735-2741, 2007. ,
,
Microparticles from apoptotic monocytes enhance nitrosative stress in human endothelial cells, Fundam. Clin. Pharmacol, vol.25, issue.6, pp.653-660, 2011. ,
Leukocyte Microparticles Stimulate Endothelial Cell Cytokine Release and Tissue Factor Induction in a JNK1 Signaling Pathway, J. Biol. Chem, vol.274, pp.23111-23118, 1999. ,
« Stimulated T cells generate microparticles, which mimic cellular contact activation of human monocytes: differential regulation of pro-and anti-inflammatory cytokine production by high-density lipoproteins, J. Leukoc. Biol, vol.83, issue.4, pp.921-927, 2008. ,
« Monocyte/Macrophage-Derived Microparticles Up-Regulate Inflammatory Mediator Synthesis by Human Airway Epithelial Cells, J. Immunol, vol.177, issue.3, pp.1975-1980, 2006. ,
, Monocyte-and Endothelial-Derived Microparticles Induce an Inflammatory Phenotype in Human Podocytes, vol.119, pp.58-66, 2011.
« Monocytic microparticles activate endothelial cells in an IL-1?-dependent manner, Blood, vol.118, issue.8, pp.2366-2374, 2011. ,
« Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1?, Proc. Natl. Acad. Sci, vol.108, pp.20684-20689, 2011. ,
, The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of
, J. Biol. Chem, vol.291, pp.10586-10601, 2016.
« Endothelial microparticles (EMP) bind and activate monocytes: elevated EMP-monocyte conjugates in multiple sclerosis, Front. Biosci. J. Virtual Libr, vol.9, pp.3137-3144, 2004. ,
« Modulation of monocyteendothelial cell interactions by platelet microparticles. », J. Clin. Invest, vol.102, issue.1, pp.136-144, 1998. ,
« Endothelial microparticles induce inflammation in acute lung injury, J. Surg. Res, vol.166, issue.1, pp.32-39, 2011. ,
« Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury, Shock Augusta Ga, vol.26, issue.5, pp.464-471, 2006. ,
,
Circulating microparticles from septic shock patients exert differential tissue expression of enzymes related to inflammation and oxidative stress, Crit. Care Med, vol.39, issue.7, pp.1739-1748, 2011. ,
, Platelet microparticles induce angiogenesis in vitro, vol.124, pp.376-384, 2004.
« Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularization », Cardiovasc. Res, vol.67, issue.1, pp.30-38, 2005. ,
« Cellderived microparticles contain caspase 3 in vitro and in vivo, J. Thromb. Haemost, vol.3, issue.5, pp.888-896, 2005. ,
« Microparticles of Human Atherosclerotic Plaques Enhance the Shedding of the Tumor Necrosis Factor-? Converting Enzyme/ADAM17 Substrates, Tumor Necrosis Factor and Tumor Necrosis Factor Receptor-1 », Am. J. Pathol, vol.171, issue.5, pp.1713-1723, 2007. ,
« Characterization of microparticles after hepatic ischemiareperfusion injury, PloS One, vol.9, issue.5, p.97945, 2014. ,
« Elevation of circulating endothelial microparticles in patients with chronic renal failure, J. Thromb. Haemost. JTH, vol.4, pp.566-573, 2006. ,
, Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy, vol.29, pp.2671-2695, 2018.
« The release of microparticles by apoptotic cells and their effects on macrophages, Apoptosis, vol.10, issue.4, pp.731-741, 2005. ,
« Internalization of microparticles by endothelial cells promotes platelet/endothelial cell interaction under flow, J. Thromb. Haemost, vol.8, pp.2810-2819, 2010. ,
« Lactadherin and clearance of platelet-derived microvesicles, Blood, vol.113, issue.6, pp.1332-1339, 2009. ,
« A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S, Biochemistry, vol.16, issue.4, pp.698-706, 1977. ,
« Vitamin K-Dependent Protein S: Beyond the Protein C Pathway, Semin. Thromb. Hemost, 2017. ,
« High affinity interaction between C4b-binding protein and vitamin K-dependent protein S in the presence of calcium. Suggestion of a third component in blood regulating the interaction », J. Biol. Chem, vol.265, pp.16082-16087, 1990. ,
« Protein S: A multifunctional anticoagulant vitamin K-dependent protein at the crossroads of coagulation, inflammation, angiogenesis, and cancer, Crit. Rev. Oncol. Hematol, vol.88, issue.3, pp.637-654, 2013. ,
« Warfarin and the vitamin K-dependent gamma-carboxylation system », Trends Mol. Med, vol.10, issue.7, pp.299-302, 2004. ,
« Vitamin K-dependent biosynthesis of gammacarboxyglutamic acid, Blood, vol.93, issue.6, pp.1798-1808, 1999. ,
« Fonctions nouvelles de Gas-6 et de la protéine S -Facteurs vitamine K-dépendants et ligands des récepteurs tyrosine kinase de la famille TAM », médecine/sciences, vol.23, pp.826-833, 2007. ,
, C4b-binding protein: a forgotten factor in thrombosis and hemostasis, vol.37, pp.355-361, 2011.
« Visualization of human C4b-binding protein and its complexes with vitamin K-dependent protein S and complement protein C4b, Proc. Natl. Acad. Sci. U. S. A, vol.80, issue.11, pp.3461-3465, 1983. ,
« Reevaluation of total, free, and bound protein S and C4b-binding protein levels in plasma anticoagulated with citrate or hirudin, Blood, vol.79, pp.3203-3211 ,
« The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. », Mol. Cell. Biol, vol.13, issue.8, pp.4976-4985, 1993. ,
, Analysis of Gas6 in human platelets and plasma, vol.25, pp.1280-1286, 2005.
, Protein C anticoagulant and cytoprotective pathways, vol.95, pp.333-345, 2012.
, Lancet Lond. Engl, vol.355, pp.1627-1632, 2000.
« Plasma protein S residues 37-50 mediate its binding to factor Va and inhibition of blood coagulation, Thromb. Haemost, vol.110, issue.2, pp.275-282, 2013. ,
« Calcium binding of bovine protein S. Effect of thrombin cleavage and removal of the gamma-carboxyglutamic acid-containing region, J. Biol. Chem, vol.261, issue.11, pp.5116-5120, 1986. ,
« Deletion or replacement of the second EGF-like domain of protein S results in loss of APC cofactor activity, Blood, vol.101, issue.4, pp.1416-1418, 2003. ,
García de Frutos, « The SHBG-like region of protein S is crucial for factor V-dependent APC-cofactor function, FEBS Lett, vol.433, issue.2, pp.28-32, 1998. ,
« Plasma protein S contains zinc essential for efficient activated protein C-independent anticoagulant activity and binding to factor ,
but not for efficient binding to tissue factor pathway inhibitor ,
, Exp. Biol, vol.23, issue.7, pp.2244-2253, 2009.
« Inhibition of intrinsic Xase by protein S: a novel regulatory role of protein S independent of activated protein C », Arterioscler. Thromb ,
, Vasc. Biol, vol.32, issue.10, pp.2387-2393, 2012.
, , 2019.
« Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis, J. Clin. Invest, vol.119, issue.10, pp.2942-2953, 2009. ,
« Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation, Blood, vol.126, pp.2247-2253, 2015. ,
Etude des mécanismes extracellulaires régulant la fonction du récepteur MerTK au cours de la phagocytose rétinienne, p.184 ,
, Biologic Functions, Signaling, and Potential Therapeutic Targeting in Human Cancer, vol.100, pp.35-83, 2008.
Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells, J. Immunol. Baltim. Md, vol.180, issue.4, pp.2522-2530, 1950. ,
« Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase, J. Biol. Chem, vol.271, pp.18355-18362, 1996. ,
, Biology of the TAM Receptors, vol.5, pp.9076-009076, 2013.
, TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis, vol.123, pp.2460-2469, 2014.
« Macrophage regulation by Tyro 3 family receptors, Curr. Opin ,
, Immunol, vol.15, issue.1, pp.31-36, 2003.
« Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family, Science, vol.293, pp.306-311, 2001. ,
« Tyro-3 family receptors are essential regulators of mammalian spermatogenesis, Nature, vol.398, pp.723-728, 1999. ,
« Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy, J. Clin. Invest, vol.115, issue.2, pp.237-246, 2005. ,
« Regulation of activated protein C by a new protein. A possible function for bovine protein S », J. Biol. Chem, vol.255, pp.5521-5524, 1980. ,
« Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C », J. Biol. Chem, vol.268, issue.4, pp.2872-2877, 1993. ,
, GAS6/TAM Pathway Signaling in Hemostasis and Thrombosis, vol.5, p.137, 2018.
, The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells* », vol.46, pp.845-852, 1972.
« Phagocytosis of apoptotic cells in homeostasis, Nat. Immunol, vol.16, issue.9, pp.907-917, 2015. ,
« Mesenchymal cells engulf and clear apoptotic footplate cells in macrophageless PU.1 null mouse embryos, Dev. Camb. Engl, vol.127, pp.5245-5252, 2000. ,
« Rod outer segment disk shedding in rat retina: relationship to cyclic lighting, Science, vol.194, pp.1071-1074, 1976. ,
« Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo, Nature, vol.467, pp.333-337, 2010. ,
, Clearance of apoptotic cells: getting rid of the corpses », vol.14, pp.277-287, 2004.
, , pp.18-2019
Signal: Phosphatidylserine Exposure ,
« An RCS-like retinal dystrophy phenotype in mer knockout mice, Invest. Ophthalmol. Vis. Sci, vol.44, issue.2, pp.826-838, 2003. ,
, TAM receptors are pleiotropic inhibitors of the innate immune response, vol.131, pp.1124-1136, 2007.
,
, Apoptotic Cells by Mouse Resident Peritoneal Macrophages, Mol. Cell. Biol, vol.34, issue.8, pp.1512-1520, 2014.
« Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells, J. Immunol. Baltim. Md, vol.178, issue.9, pp.5635-5642, 1950. ,
« Opposing Roles of Tyrosine Kinase Receptors Mer and Axl Determine Clinical Outcomes in Experimental Immune-Mediated Nephritis, J. Immunol ,
, , vol.197, p.2016, 1950.
« Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells, Cell Death Dis, vol.6, issue.2, pp.1646-1646, 2015. ,
« Phagocytosis: receptors, signal integration, and the cytoskeleton », Immunol. Rev, vol.262, issue.1, pp.193-215, 2014. ,
« The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function, Curr. Opin. Cell Biol, vol.20, issue.4, pp.415-426, 2008. ,
, Phagocytosis: A Fundamental Process in Immunity, vol.2017, 2017.
« Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase, J. Exp. Med, vol.196, issue.1, pp.135-140, 2002. ,
« A Protective Role of Mer Receptor Tyrosine Kinase in Nephrotoxic Serum-induced Nephritis, Clin. Immunol. Orlando Fla, vol.136, issue.2, pp.236-244, 2010. ,
« A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock, J. Immunol. Baltim. Md, vol.162, issue.6, pp.3498-3503, 1950. ,
« Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells, Blood, vol.109, issue.2, pp.653-660, 2007. ,
, Mer receptor tyrosine kinase negatively regulates lipoteichoic acid-induced inflammatory response via PI3K/Akt and SOCS3 », vol.76, pp.98-107, 2016.
« Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-?B activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury, J. Leukoc. Biol, vol.91, issue.6, pp.921-932, 2012. ,
« SOCS proteins, cytokine signalling and immune regulation », Nat. Rev. Immunol, vol.7, issue.6, pp.454-465, 2007. ,
« Mechanism of Mer receptor tyrosine kinase inhibition of glomerular endothelial cell inflammation, J. Leukoc. Biol, vol.103, issue.4, pp.709-717, 2018. ,
« Essential role of Gas6 for glomerular injury in nephrotoxic nephritis, J. Clin. Invest, vol.110, issue.2, pp.239-246, 2002. ,
« Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes, Blood, vol.111, issue.8, pp.4096-4105, 2008. ,
« Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma, J. Immunol. Baltim. Md, vol.192, issue.8, pp.3569-3581, 1950. ,
« M2 macrophages phagocytose rituximab-opsonized leukemic targets more efficiently than m1 cells in vitro, J. Immunol. Baltim. Md, vol.182, issue.7, pp.4415-4422, 1950. ,
« Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment, Mol. Cancer, vol.18, issue.1 ,
« Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy », Am. J. Pathol, vol.187, issue.9, pp.1971-1983, 2017. ,
, « Gas6/TAM Receptors in Systemic Lupus Erythematosus », Disease Markers, 2019.
,
,
, Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase C?, and p38 Mitogen-activated Protein Kinase (MAPK), J. Biol. Chem, vol.286, pp.33335-33344, 2011.
« Influence of eye pigmentation and light deprivation on inherited retinal dystrophy in the rat, Exp. Eye Res, vol.21, issue.2, pp.167-192, 1975. ,
« Homozygous deletion in the coding sequence of the c-mer gene in RCS rats unravels general mechanisms of physiological cell adhesion and apoptosis, Neurobiol. Dis, vol.7, pp.586-599, 2000. ,
« Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat, Hum. Mol. Genet, vol.9, issue.4, pp.645-651, 2000. ,
, A Comprehensive Review of Mutations in the MERTK Proto
, Adv. Exp. Med. Biol, vol.854, pp.259-265, 2016.
« Defective phagocytosis of isolated rod outer segments by RCS rat retinal pigment epithelium in culture, Science, vol.197, pp.1001-1003, 1977. ,
« Pigment epithelium-photoreceptor interactions in the normal and dystrophic rat retina, Exp. Eye Res, vol.21, issue.2, pp.153-166, 1975. ,
« Histological Evaluation of Proximal Tubule Cell Injury in Isolated Perfused Pig Kidneys Exposed to Cold Ischemia, J. Surg. Res, vol.82, issue.2, pp.228-233, 1999. ,
« Mertk Triggers Uptake of Photoreceptor Outer Segments during Phagocytosis by Cultured Retinal Pigment Epithelial Cells, J. Biol. Chem, vol.277, pp.17016-17022, 2002. ,
, Effect of ischemia preconditioning on renal ischemia/reperfusion injury in rats, vol.38, pp.842-854
« Severe bilateral ischemic-reperfusion renal injury: hyperacute and acute changes in apparent diffusion coefficient, T1, and T2 mapping with immunohistochemical correlations, Sci. Rep, vol.7, issue.1, pp.1-10, 2017. ,
« Ischemia/reperfusioninduced renal failure in rats as a model for evaluating cell therapies, Ren. Fail, vol.34, issue.10, pp.1324-1332, 2012. ,
, Effect of dexmedetomidine on ischemia-reperfusion injury in rat kidney: a histopathologic study, vol.31, pp.70-74, 2009.
« Renal Cortical Lactate Dehydrogenase: A Useful, Accurate, Quantitative Marker of Tubular Injury and Acute Renal Failure, PloS One, vol.8, issue.6, p.66776, 2013. ,
, Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury, vol.62, pp.237-244, 2002.
Cell biology and molecular mechanisms of injury in ischemic acute renal failure, Curr. Opin. Nephrol. Hypertens, vol.9, issue.4, pp.427-434, 2000. ,
« The administration of erythropoietin attenuates kidney injury induced by ischemia/reperfusion with increased activation of Wnt/?-catenin signaling, J. Formos. Med. Assoc, vol.114, issue.5, pp.430-437, 2015. ,
« The Dual Role of Inducible Nitric Oxide Synthase in Myocardial Ischemia/Reperfusion Injury: Friend or Foe?, Oxidative Medicine and Cellular Longevity, 2018. ,
,
« Distant effects of unilateral renal ischemia/reperfusion on contralateral kidney but not lung in rats: the roles of ROS and iNOS », Can, J. Physiol. Pharmacol, vol.94, issue.5, pp.477-487, 2016. ,
« Neutrophil activation in response to monomeric myeloperoxidase, Biochem. Cell Biol. Biochim. Biol. Cell, vol.96, issue.5, pp.592-601, 2018. ,
dendritic cells, and kidney ischemia-reperfusion injury, Semin. Nephrol, vol.30, issue.3, pp.268-277, 2010. ,
« Interplay between ROS and Antioxidants during Ischemia-Reperfusion Injuries in Cardiac and Skeletal Muscle », Int. J. Mol. Sci, vol.19, issue.2, 2018. ,
, Mediators of Inflammation in Acute Kidney Injury, 2009.
« TNF-alpha-dependent bilateral renal injury is induced by unilateral renal ischemia-reperfusion », Am. J. Physiol. Heart Circ. Physiol, vol.282, issue.2, pp.540-546, 2002. ,
« Detrimental hemodynamic and inflammatory effects of microparticles originating from septic rats, Crit. Care Med, vol.37, issue.6, pp.2045-2050, 2009. ,
« Platelet-derived microparticles promote endothelial cell proliferation in hypertension via miR-142-3p », FASEB J, vol.32, issue.7, pp.3912-3923, 2018. ,
« Increased Microparticle Production and Impaired Microvascular Endothelial Function in Aldosterone-Salt-Treated Rats: Protective Effects of Polyphenols, PLOS ONE, vol.7, issue.7, p.39235, 2012. ,
« Microparticles mediate hepatic ischemia-reperfusion injury and are the targets of Diannexin (ASP8597), PloS One, vol.9, issue.9, p.104376, 2014. ,
« Impact of pre-analytical parameters on the measurement of circulating microparticles: towards standardization of protocol, J. Thromb. Haemost. JTH, vol.10, issue.3, pp.437-446, 2012. ,
« Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis, J. Immunol. Baltim. Md, vol.201, issue.9, pp.2602-2611, 1950. ,