,
Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5, 2016. ,
, Antimicrob Agents Chemother, vol.60, pp.5085-5092
,
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats, vol.1
, Antimicrob Agents Chemother
, , 2014.
, Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 2. Colistin, Antimicrob Agents Chemother, vol.58, pp.3950-3956
, , 2018.
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 6
, Antimicrob Agents Chemother, vol.62
, , 2015.
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats, p.3
, Antimicrob Agents Chemother, vol.59, pp.6646-6653
, , 2016.
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats, vol.4
, Antimicrob Agents Chemother, vol.60, pp.3196-3204
Pglycoprotein-mediated transport of moxifloxacin in a Calu-3 lung epithelial cell model, Antimicrobial agents and chemotherapy, vol.53, pp.1457-1462, 2009. ,
Development of a new pre-and post-processing tool (SADAPT-TRAN) for nonlinear mixed-effects modeling in S-ADAPT, Aaps J, vol.13, pp.201-212, 2011. ,
,
Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5, 2016. ,
, Antimicrob Agents Chemother, vol.60, pp.5085-5092
Aerosolised antibiotics: a critical appraisal of their use, Expert opinion on drug delivery, vol.3, pp.71-86, 2006. ,
,
, Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 1
, Antimicrobial agents and chemotherapy, vol.58, pp.3942-3949
Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs, Journal of pharmaceutical sciences, vol.99, pp.2240-2255, 2010. ,
TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens, Journal of antimicrobial chemotherapy, vol.63, pp.716-720, 2009. ,
Clinical pharmacokinetics and pharmacodynamics of oxazolidinones, Clinical pharmacokinetics, vol.57, pp.559-575, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01800323
, , 2012.
, Pulmonary disposition of tedizolid following administration of once-daily oral 200-milligram tedizolid phosphate in healthy adult volunteers, Antimicrobial agents and chemotherapy, vol.56, pp.2627-2634
,
Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro, Pharmaceutical research, vol.34, pp.2477-2487, 2017. ,
, , 2009.
, Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs, Pharmaceutical research, vol.26, pp.1816-1831
Modulation of P-glycoprotein but not MRP1-or BCRP-mediated drug resistance by LY335979, International journal of cancer, vol.103, pp.121-125, 2003. ,
Pglycoprotein-mediated transport of moxifloxacin in a Calu-3 lung epithelial cell model, Antimicrobial agents and chemotherapy, vol.53, pp.1457-1462, 2009. ,
Morphometric comparisons of rat alveolar macrophages, pulmonary interstitial macrophages, and blood monocytes, Experimental lung research, vol.18, pp.479-496, 1992. ,
Cell size of alveolar macrophages: an interspecies comparison, Environmental health perspectives, vol.105, p.1261, 1997. ,
Response of pulmonary cellular defenses to the inhalation of high concentrations of diesel exhaust, Journal of Toxicology and Environmental Health, Part A Current Issues, vol.13, pp.919-944, 1984. ,
Interpretation of antibiotic concentration ratios measured in epithelial lining fluid, Antimicrobial agents and chemotherapy, vol.52, pp.24-36, 2008. ,
,
Aerosol therapy with colistin methanesulfonate: a biopharmaceutical issue illustrated in rats, Antimicrobial agents and chemotherapy, vol.54, pp.3702-3707, 2010. ,
Linezolid: the first oxazolidinone antimicrobial, Annals of internal medicine, vol.138, p.135, 2003. ,
, , 2018.
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats. 6. Aminoglycosides. Antimicrobial agents and chemotherapy
, , 2019.
, Pulmonary Pharmacokinetics of Oseltamivir Carboxylate in Rats after Nebulization or Intravenous Administration of Its Prodrug, Oseltamivir Phosphate, Antimicrobial agents and chemotherapy, vol.63, pp.74-93
,
The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier, Molecular pharmaceutics, vol.11, pp.995-1006, 2014. ,
, Characterization of the Calu, vol.3, 2000.
, cell line as a tool to screen pulmonary drug delivery, International Journal of Pharmaceutics, vol.208, pp.1-11
Relative contributions of active mediated transport and passive diffusion of fluoroquinolones with various lipophilicities in a Calu-3 lung epithelial cell model, Antimicrobial agents and chemotherapy, vol.54, pp.543-545, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02466429
In Vitro Mechanistic Study of the Distribution of Lascufloxacin into Epithelial Lining Fluid, Antimicrobial agents and chemotherapy, vol.63, pp.2208-2226, 2019. ,
Interpretation of epithelial lining fluid concentrations of antibiotics against methicillin resistant Staphylococcus aureus, Infection & chemotherapy, vol.46, pp.219-225, 2014. ,
Respiratory physiology: the essentials, 2012. ,
The Respiratory System, 2011. ,
In vitro cell culture models for the assessment of pulmonary drug disposition, Expert opinion on drug metabolism & toxicology, vol.4, pp.333-345, 2008. ,
Regulation of mucociliary clearance in health and disease, European Respiratory Journal, vol.13, pp.1177-1188, 1999. ,
Preclinical models for pulmonary drug delivery, Expert opinion on drug delivery, vol.6, pp.1231-1245, 2009. ,
Mechanisms of macromolecule absorption by the lungs, Advanced Drug Delivery Reviews, vol.19, pp.3-36, 1996. ,
Fundamentals of pulmonary drug delivery, Respiratory medicine, vol.97, pp.382-387, 2003. ,
Pulmonary absorption of peptides and proteins, Drug Delivery, vol.2, pp.1-20, 1995. ,
Cell number and distribution in human and rat airways, American journal of respiratory cell and molecular biology, vol.10, pp.613-624, 1994. ,
Allometric relationships of cell numbers and size in the mammalian lung, Am J Respir Cell Mol Biol, vol.6, pp.235-243, 1992. ,
Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution, Journal of Applied Physiology, vol.60, pp.532-538, 1986. ,
Database of bronchoalveolar lavage fluid proteins, Journal of Chromatography B, vol.771, pp.221-236, 2002. ,
Human airway ion transport. Part one, American journal of respiratory and critical care medicine, vol.150, pp.271-281, 1994. ,
, Am Rev Respir Dis, vol.143, pp.1096-1101, 1991.
Altered epithelial lining fluid parameters in old normal individuals, Journal of gerontology, vol.47, pp.171-176, 1992. ,
Analysis of vancomycin entry into pulmonary lining fluid by bronchoalveolar lavage in critically ill patients, Antimicrobial agents and chemotherapy, vol.37, pp.281-286, 1993. ,
Protein binding of antimicrobials: clinical pharmacokinetic and therapeutic implications, Clinical pharmacokinetics, vol.2, pp.252-268, 1977. ,
Correction of protein binding defect in uremic sera by charcoal treatment, Translational Research, vol.87, pp.637-647, 1976. ,
Pulmonary surfactant: functions and molecular composition, Biochimica et Biophysica Acta (BBA) -Molecular Basis of Disease, vol.1408, pp.79-89, 1998. ,
Molecular structures and interactions of pulmonary surfactant components, European journal of biochemistry, vol.244, pp.675-693, 1997. ,
Prodrugs for nasal drug delivery, Advanced drug delivery reviews, vol.29, pp.135-146, 1998. ,
Cell number and cell characteristics of the normal human lung, American Review of Respiratory Disease, vol.126, pp.332-337, 1982. ,
Cell size of alveolar macrophages: an interspecies comparison, Environmental health perspectives, vol.105, p.1261, 1997. ,
The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity, Blood, vol.57, pp.894-899, 1981. ,
Volume and osmotic properties of human neutrophils, Blood, vol.81, pp.2774-2780, 1993. ,
Interpretation of antibiotic concentration ratios measured in epithelial lining fluid, Antimicrobial agents and chemotherapy, vol.52, pp.24-36, 2008. ,
Determination of pulmonary parenchymal tissue volume and pulmonary capillary blood flow in man, Journal of Applied Physiology, vol.14, pp.541-551, 1959. ,
Measurement of cardiac output in man using the technique of catheterization of the right auricle or ventricle, The Journal of clinical investigation, vol.24, pp.106-116, 1945. ,
Simultaneous determinations of the resting arteriovenous oxygen difference by the acetylene and direct Fick methods, The Journal of clinical investigation, vol.29, pp.651-659, 1950. ,
The cardiac output in male subjects as measured by the technique of right atrial catheterization. Normal values with observations on the effect of anxiety and tilting, The Journal of clinical investigation, vol.24, pp.326-331, 1945. ,
Studies of the pulmonary circulation. I. The circulation time from the pulmonary artery to the femoral artery and the quantity of blood in the lungs in normal individuals, The Journal of clinical investigation, vol.28, pp.1134-1137, 1949. ,
Antibiotic pharmacokinetic considerations in pulmonary infections, pp.168-182, 1991. ,
Receptor-mediated endocytosis of macromolecules and strategy to enhance their transport in alveolar epithelial cells, Expert opinion on drug delivery, vol.12, pp.813-825, 2015. ,
,
Goodman and Gilman's manual of pharmacology and therapeutics, 2018. ,
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview, Advanced drug delivery reviews, vol.64, pp.138-153, 2012. ,
N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein, Journal of Biological Chemistry, vol.268, pp.7474-7481, 1993. ,
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants, Biochimica et Biophysica Acta (BBA)-Biomembranes, vol.455, pp.152-162, 1976. ,
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade, Cancer letters, vol.370, pp.153-164, 2016. ,
Is the multidrug transporter a flippase, Trends in biochemical sciences, vol.17, pp.18-21, 1992. ,
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease, Cell, vol.75, pp.451-462, 1993. ,
The human MDR3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice, FEBS letters, vol.354, pp.263-266, 1994. ,
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 Pglycoprotein specifically translocates phosphatidylcholine, Cell, vol.87, pp.507-517, 1996. ,
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues, Proceedings of the National Academy of Sciences, vol.84, pp.7735-7738, 1987. ,
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites, Proceedings of the National Academy of Sciences, vol.86, pp.695-698, 1989. ,
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes, Drug Metabolism and Disposition, vol.28, pp.655-660, 2000. ,
Homozygous disruption of the mdr1a P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs, Acta oto-laryngologica, vol.121, pp.735-742, 2001. ,
Placental Pglycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice, Reproductive toxicology, vol.12, pp.457-463, 1998. ,
Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16, Cancer research, vol.48, pp.1926-1929, 1988. ,
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs, Cell, vol.77, pp.491-502, 1994. ,
P-glycoprotein in the bloodbrain barrier of mice influences the brain penetration and pharmacological activity of many drugs, The Journal of clinical investigation, vol.97, pp.2517-2524, 1996. ,
Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein, Cancer chemotherapy and pharmacology, vol.40, pp.13-19, 1997. ,
In vivo circumvention of P-glycoprotein-mediated multidrug resistance of tumor cells with SDZ PSC 833, Cancer Research, vol.51, pp.4226-4233, 1991. ,
The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A: implications for drug-drug interactions and pharmacological activity of the main metabolite, Drug Metabolism and Disposition, vol.26, pp.802-811, 1998. ,
In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative, Cancer research, vol.53, pp.4595-4602, 1993. ,
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR. Cancer letters, vol.146, pp.117-126, 1999. ,
Reversal of multidrug resistance by the Pglycoprotein modulator, LY335979, from the bench to the clinic, Current medicinal chemistry, vol.8, pp.39-50, 2001. ,
In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576, Cancer research, vol.61, pp.749-758, 2001. ,
Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance, Cancer research, vol.60, pp.2964-2972, 2000. ,
Overexpression of a transporter gene in a multidrugresistant human lung cancer cell line, Science, vol.258, pp.1650-1654, 1992. ,
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates, Journal of Biological Chemistry, vol.269, pp.27807-27810, 1994. ,
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport, Proceedings of the National Academy of Sciences, vol.91, pp.13033-13037, 1994. ,
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells, The Journal of clinical investigation, vol.97, pp.1211-1218, 1996. ,
ATP-dependent 17-Estradiol 17-(-D-Glucuronide) Transport by Multidrug Resistance Protein (MRP) INHIBITION BY CHOLESTATIC STEROIDS, Journal of Biological Chemistry, vol.271, pp.9683-9689, 1996. ,
The pharmacological phenotype of combined multidrug-resistance mdr1a/1b-and mrp1-deficient mice, Cancer research, vol.61, pp.1469-1476, 2001. ,
Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells, Molecular pharmacology, vol.55, pp.929-937, 1999. ,
Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs, Pharmaceutical research, vol.26, pp.1816-1831, 2009. ,
The role of transporters in the pharmacokinetics of orally administered drugs, Pharmaceutical research, vol.26, pp.2039-2054, 2009. ,
Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein, Journal of Biological Chemistry, vol.265, pp.10073-10080, 1990. ,
A multidrug resistance transporter from human MCF-7 breast cancer cells, Proceedings of the National Academy of Sciences, vol.95, pp.15665-15670, 1998. ,
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues, Cancer research, vol.61, pp.3458-3464, 2001. ,
Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line, Cancer research, vol.59, pp.4559-4563, 1999. ,
Co-administration of GF120918 significantly increases the systemic exposure to oral paclitaxel in cancer patients, British journal of cancer, vol.84, p.42, 2001. ,
Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C, Cancer research, vol.58, pp.5850-5858, 1998. ,
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein, Cancer research, vol.60, pp.47-50, 2000. ,
Fumitremorgin C analogs that reverse mitoxantrone resistance in human colon carcinoma cells, Medicinal Chemistry Research, vol.9, p.424, 1999. ,
Inhibition of BCRPmediated drug efflux by fumitremorgin-type indolyl diketopiperazines, Bioorganic & medicinal chemistry letters, vol.11, pp.29-32, 2001. ,
A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability, Pharmaceutical research, vol.12, pp.413-420, 1995. ,
The role of BCS (biopharmaceutics classification system) and BDDCS (biopharmaceutics drug disposition classification system) in drug development, Journal of pharmaceutical sciences, vol.102, pp.34-42, 2013. ,
Predicting drug disposition via application of BCS: transport/absorption/elimination interplay and development of a biopharmaceutics drug disposition classification system, Pharmaceutical research, vol.22, pp.11-23, 2005. ,
BDDCS applied to over 900 drugs, The AAPS journal, vol.13, pp.519-547, 2011. ,
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs, Journal of Pharmacology and Experimental Therapeutics, vol.303, pp.1029-1037, 2002. ,
Biopharmaceutical characterization of nebulized antimicrobial agents in rats, p.1, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-02477510
, Antimicrobial agents and chemotherapy, vol.58, pp.3942-3949
, Biopharmaceutical characterization of nebulized antimicrobial agents in rats, p.3, 2015.
URL : https://hal.archives-ouvertes.fr/hal-02470454
, Antimicrobial agents and chemotherapy, vol.59, pp.6646-6647
Pglycoprotein-mediated transport of moxifloxacin in a Calu-3 lung epithelial cell model, Antimicrobial agents and chemotherapy, vol.53, pp.1457-1462, 2009. ,
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice, Journal of the National Cancer Institute, vol.59, pp.221-226, 1977. ,
Permeability characteristics of calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats, Journal of drug targeting, vol.10, pp.31-40, 2002. ,
Pharmaceutical applications of the Calu-3 lung epithelia cell line, Expert opinion on drug delivery, vol.10, pp.1287-1302, 2013. ,
RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models, Journal of Pharmacy and Pharmacology, vol.61, pp.583-591, 2009. ,
Drug Transporter Protein Quantification of Immortalized Human Lung Cell Lines Derived from Tracheobronchial Epithelial Cells (C alu-3 and BEAS 2-B), Bronchiolar-Alveolar Cells (NCI-H 292 and NCI-H 441), and Alveolar Type II-like Cells (A 549) by Liquid Chromatography-Tandem Mass Spectrometry, Journal of pharmaceutical sciences, vol.104, pp.3029-3038, 2015. ,
Time-and passagedependent characteristics of a Calu-3 respiratory epithelial cell model, Drug development and industrial pharmacy, vol.36, pp.1207-1214, 2010. ,
Active Mediated Transport of Chloramphenicol and Thiamphenicol in a Calu-3 Lung Epithelial Cell Model, Journal of pharmaceutical sciences, vol.107, pp.1178-1184, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02481308
Peripheral airway cell differentiation in human lung cancer cell lines, Cancer research, vol.50, pp.5481-5487, 1990. ,
The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier, Molecular pharmaceutics, vol.11, pp.995-1006, 2014. ,
CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells, American journal of respiratory cell and molecular biology, vol.10, pp.38-47, 1994. ,
Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies, Cell and tissue research, vol.308, pp.391-400, 2002. ,
Effect of cigarette smoke extract on P-glycoprotein function in primary cultured and newly developed alveolar epithelial cells, Drug metabolism and pharmacokinetics, vol.31, pp.417-424, 2016. ,
An optimised human cell culture model for alveolar epithelial transport, PloS one, vol.11, p.165225, 2016. ,
Application of RPMI 2650 nasal cell model to a 3D printed apparatus for the testing of drug deposition and permeation of nasal products, European Journal of Pharmaceutics and Biopharmaceutics, vol.107, pp.223-233, 2016. ,
Transport mechanisms at the pulmonary mucosa: implications for drug delivery, Expert opinion on drug delivery, vol.13, pp.667-690, 2016. ,
Drug absorption from the lung, Biochemical Pharmacology, vol.27, pp.381-385, 1978. ,
Pharmacokinetics of colistin methansulphonate (CMS) and colistin after CMS nebulisation in baboon monkeys, Pharmaceutical research, vol.32, pp.3403-3414, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-02478032
Tissue concentrations: do we ever learn, Journal of Antimicrobial Chemotherapy, vol.61, pp.235-237, 2007. ,
Pharmacokinetic measurement of drugs in lung epithelial lining fluid by microdialysis: aminoglycoside antibiotics in rat bronchi, Journal of pharmacological and toxicological methods, vol.29, pp.93-98, 1993. ,
Application of microdialysis in pharmacokinetic studies, Pharmaceutical research, vol.14, pp.267-288, 1997. ,
Microdialysis study of imipenem distribution in skeletal muscle and lung extracellular fluids of noninfected rats, Antimicrobial agents and chemotherapy, vol.49, pp.2356-2361, 2005. ,
Antimicrobial chemotherapy and lung microdialysis: a review, International journal of antimicrobial agents, vol.36, pp.491-500, 2010. ,
Microdialysis study of imipenem distribution in skeletal muscle and lung extracellular fluids of Acinetobacter baumannii-infected rats, Antimicrobial agents and chemotherapy, vol.50, pp.2265-2267, 2006. ,
Lung microdialysis study of levofloxacin in rats following intravenous infusion at steady state, Antimicrobial agents and chemotherapy, vol.52, pp.3074-3077, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00319455
Penetration of cefaclor into the interstitial space fluid of skeletal muscle and lung tissue in rats, Pharmaceutical research, vol.18, pp.1310-1314, 2001. ,
Evaluation of gatifloxacin penetration into skeletal muscle and lung by microdialysis in rats, International journal of pharmaceutics, vol.358, pp.96-101, 2008. ,
Lung microdialysis-a powerful tool for the determination of exogenous and endogenous compounds in the lower respiratory tract (mini-review), The AAPS journal, vol.7, pp.600-608, 2005. ,
The impact of perioperative atelectasis on antibiotic penetration into lung tissue: an in vivo microdialysis study, Intensive care medicine, vol.34, p.1827, 2008. ,
Closed-chest microdialysis to measure antibiotic penetration into human lung tissue, American journal of respiratory and critical care medicine, vol.165, pp.273-276, 2002. ,
Microdialysis in peripheral tissues, Advanced drug delivery reviews, vol.45, pp.189-216, 2000. ,
Extracellular concentrations of fosfomycin in lung tissue of septic patients, Journal of antimicrobial chemotherapy, vol.65, pp.995-998, 2010. ,
,
Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis, pp.297-304, 2019. ,
Bronchoalveolar Lavage 1, 2, American Review of Respiratory Disease, vol.135, pp.250-263, 1987. ,
Validity of markers of dilution in small volume lung lavage, American journal of respiratory and critical care medicine, vol.160, pp.778-784, 1999. ,
Pharmacokinetics of antibiotics in the lungs, European Respiratory Journal, vol.3, pp.715-722, 1990. ,
Pulmonary disposition of antimicrobial agents: methodological considerations, Antimicrobial agents and chemotherapy, vol.36, p.1171, 1992. ,
Limitations of using urea to quantify epithelial lining fluid recovered by bronchoalveolar lavage, American Review of Respiratory Disease, vol.135, pp.1276-1280, 1987. ,
Interpretation of epithelial lining fluid concentrations of antibiotics against methicillin resistant Staphylococcus aureus, Infection & chemotherapy, vol.46, pp.219-225, 2014. ,
In vivo, in vitro and ex vivo models to assess pulmonary absorption and disposition of inhaled therapeutics for systemic delivery, Advanced drug delivery reviews, vol.58, pp.1030-1060, 2006. ,
The isolated perfused lung for drug absorption studies, Drug Absorption Studies, pp.135-163, 2008. ,
Isolated perfused murine lung: a well characterized preparation for studying lung vascular function, Drug Discovery Today: Disease Models, vol.7, pp.131-135, 2010. ,
Pulmonary and systemic pharmacokinetics of inhaled and intravenous colistin methanesulfonate in cystic fibrosis patients: targeting advantage of inhalational administration, Antimicrobial agents and chemotherapy AAC, pp.1705-1718, 2014. ,
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats. 6. Aminoglycosides. Antimicrobial agents and chemotherapy, 2018.
Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 2. Colistin, Antimicrobial agents and chemotherapy, vol.58, pp.3950-3956, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-02477510
Biopharmaceutical characterization of nebulized antimicrobial agents in rats, vol.4, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02470454
, Aztreonam. Antimicrobial agents and chemotherapy, vol.60, pp.3196-3198
, Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats, p.5, 2016.
, Antimicrobial agents and chemotherapy, vol.60, pp.5085-5087
Clinical pharmacokinetics of the prodrug oseltamivir and its active metabolite Ro 64-0802, Clinical pharmacokinetics, vol.37, pp.471-484, 1999. ,
TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens, Journal of antimicrobial chemotherapy, vol.63, pp.716-720, 2009. ,
Clinical pharmacokinetics and pharmacodynamics of oxazolidinones, Clinical pharmacokinetics, vol.57, pp.559-575, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01800323
Intracellular activity of tedizolid phosphate and ACH-702 versus Mycobacterium tuberculosis infected macrophages, Annals of clinical microbiology and antimicrobials, vol.13, p.13, 2014. ,
Pulmonary disposition of tedizolid following administration of once-daily oral 200-milligram tedizolid phosphate in healthy adult volunteers, Antimicrobial agents and chemotherapy, vol.56, pp.2627-2634, 2012. ,
Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system, Antimicrobial agents and chemotherapy, vol.53, pp.4753-4761, 2009. ,
Aerosol therapy with colistin methanesulfonate: a biopharmaceutical issue illustrated in rats, Antimicrobial agents and chemotherapy, vol.54, pp.3702-3707, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02472561
Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate, Journal of Antimicrobial Chemotherapy, vol.53, pp.837-840, 2004. ,
Pulmonary Pharmacokinetics of Oseltamivir Carboxylate in Rats after Nebulization or Intravenous Administration of Its Prodrug, Oseltamivir Phosphate, Antimicrobial agents and chemotherapy, vol.63, pp.74-93, 2019. ,
URL : https://hal.archives-ouvertes.fr/hal-02477849
Relative contributions of active mediated transport and passive diffusion of fluoroquinolones with various lipophilicities in a Calu-3 lung epithelial cell model, Antimicrobial agents and chemotherapy, vol.54, pp.543-545, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02466429
Endoscopic sensing of alveolar pH, Biomedical optics express, vol.8, pp.243-259, 2017. ,
Physiology of the alveolar surface network, Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, vol.135, pp.39-104, 2003. ,
Mechanisms of acid and base secretion by the airway epithelium, The Journal of membrane biology, vol.211, pp.139-150, 2006. ,
Intrapulmonary pharmacokinetics of lascufloxacin in healthy adult volunteers, Antimicrobial agents and chemotherapy, vol.62, pp.2169-2186, 2018. ,
In Vitro Mechanistic Study of the Distribution of Lascufloxacin into Epithelial Lining Fluid, Antimicrobial agents and chemotherapy, vol.63, pp.2208-2226, 2019. ,
In vitro biopharmaceutical evaluation of ciprofloxacin/metal cation complexes for pulmonary administration, European Journal of Pharmaceutical Sciences, vol.97, pp.92-98, 2017. ,
URL : https://hal.archives-ouvertes.fr/inserm-01416565
Amorphous calcium carbonate based-microparticles for peptide pulmonary delivery, ACS applied materials & interfaces, vol.8, pp.1164-1175, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02484982
, , 2015.
, Ciprofloxacin-loaded inorganic-organic composite microparticles to treat bacterial lung infection, Molecular pharmaceutics, vol.13, pp.100-112
New aerosol formulation to control ciprofloxacin pulmonary concentration, Journal of Controlled Release, vol.271, pp.118-126, 2018. ,
URL : https://hal.archives-ouvertes.fr/inserm-02379277