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Cognition sociale et neuroimagerie dans le vieillissement normal et les dégénérescences lobaires frontotemporales

Abstract : Social cognition refers to the set of processes that allow us to interact and to adjust our behaviours in the social world. It has been suggested that behavioural modifications observed in normal and pathological aging can be due to changes in social cognition abilities, in particular in Theory of mind (ToM). The study of social cognition within the framework of frontotemporal lobar degenerations (DLFT), pathologies associated with important behavioural disturbances, takes its full meaning. However, relationships between ToM and other cognitive functions are still poorly understood, both on cognitive and cerebral levels. The main aim of these thesis was to contribute to broader understanding of joint working of those processes with the support of brain imaging. By adopting an ecological approach, our results have underlined links between the processes that contribute to ToM deficits and the neural basis on which they rely. They further highlighted subtle and early ToM dysfunctioning in subjects carrying a genetic mutation responsible of the development of a particular FTLD disease, in a presymptomatic stage.
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Submitted on : Thursday, March 26, 2020 - 10:39:11 AM
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Remi Laillier. Cognition sociale et neuroimagerie dans le vieillissement normal et les dégénérescences lobaires frontotemporales. Psychologie. Normandie Université, 2019. Français. ⟨NNT : 2019NORMC047⟩. ⟨tel-02519574⟩

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