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Encapsulation et élicitation de microalgues pour la cosmétique

Abstract : This work focuses on encapsulation of microalgae to produce molecules of interest for cosmetics. Using liquid-core and semi-permeable hydrogel shell capsules, we are able to protect the cells from external constraints while feeding them through them semi-permeable membrane. Additionally, the capsules enable us to manipulate the cells in an easier way. These advantages combined, we grow microalgae at much higher concentrations than what we are able to do in bulk (10^10 vs 10^7 /mL); change the medium smoothly and elicitate these cells to induce the production of molecules of interest. Encapsulation is shown to carry no negative impact on the cells. Finally, we leverage on the capsules to demonstrate a proof of concept for combinatorial screening based on adsorption of colloids on our capsules. That enable us to screen for sequences of culture conditions, which is otherwise quite difficult to perform because of the large numbers involved.
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Contributor : Édouard Duliège <>
Submitted on : Thursday, March 19, 2020 - 6:05:47 PM
Last modification on : Saturday, September 26, 2020 - 11:44:07 PM
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  • HAL Id : tel-02512611, version 1



M Duliège. Encapsulation et élicitation de microalgues pour la cosmétique. Matière Molle [cond-mat.soft]. UPMC - Université Paris 6 Pierre et Marie Curie, 2017. Français. ⟨tel-02512611⟩



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