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CSF inflammation was significantly more frequent in LE/-and LE/+ patients (14/17, 82.4% ,
, All but 1 of the sera tested for CASPR2-Ab (n=52: 16 LE, vol.9, p.11
, Among all tested CSF, 31/48 (64.6%) samples were positive for CASPR2-Ab. CSF detection rates of CASPR2-Ab did not differ between LE/-and LE/+ groups (16/18 vs. 11/11, p=0.5)
detection of CASPR2-Ab in CSF was significantly more frequent in LE patients than in those from both the PNH ,
, /12, p=3.4x10 -8 ) groups. In addition, CASPR2-Ab were more commonly found in the CSF of PNH
, Serum LGI1-Ab were only detected in PNH/+ patients (10/15, 66.7%, p=2x10 -6 ) and only in those with malignant thymoma (10/13 vs. 0/37, p=2.7x10 -8 ), PNH/-patients who had overlapping PNH and limbic features
, belonging to a patient of the PNH/+ group. Serum was still available for the establishment of CASPR2-Ab end-point dilution for 43 patients, 02%) was positive at very low titers (end-point dilution, 1:20), vol.9
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