, , p.372
, Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study, Rheumatol 373 Int, vol.37, pp.487-493, 2017.
Rheumatoid arthritis 375 and excess mortality: down but not out. A primary care cohort study using data from Clinical 376 ,
, Practice Research Datalink. Rheumatology, vol.57, pp.977-981, 2018.
Risk of incident 378 cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies ,
, Ann Rheum Dis, vol.71, pp.1524-1529, 2012.
,
, Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A 382 Population Record-Linkage Cohort Study in England, PloS One, vol.11, p.151245, 2016.
,
, Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a 385 population-based cohort study, Arthritis Rheum, vol.52, pp.402-411, 2005.
Cardiac endothelium-387 myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection 388 fraction, Eur Heart J, vol.36, pp.2050-2060, 2015. ,
Microvascular endothelial 390 dysfunction in rheumatoid arthritis, Nat Rev Rheumatol, vol.14, pp.404-420, 2018. ,
Mechanisms of endothelial 392 dysfunction in rheumatoid arthritis: lessons from animal studies, Arthritis Res Ther, vol.16, p.202, 2014. ,
,
Histoire de la polyarthrite rhumatoïde, Rhumatol Prat, pp.18-20 ,
, Polyarthrite rhumatoïde -Définition, Symptômes, Causes. Santepratique.fr
Epidémiologie et physiopathologie de la polyarthrite rhumatoïde, Actual Pharm, 2013. ,
Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Arthritis Rheum, vol.62, issue.6, pp.1576-1582, 2010. ,
Polyarthrite Rhumatoïde -Recommandations Professionnelles, 2007. ,
Impact of rheumatoid arthritis on career progression, productivity, and employability: The PRET Study, Joint Bone Spine, vol.82, issue.5, pp.306-311, 2015. ,
The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis, Arthritis Rheum, vol.54, issue.4, pp.1117-1121, 2006. ,
When and where does rheumatoid arthritis begin?, Joint Bone Spine, vol.79, issue.6, pp.550-554, 2012. ,
The Pathogenesis of Rheumatoid Arthritis, N Engl J Med, vol.365, issue.23, pp.2205-2219, 2011. ,
The impact of pregnancy on rheumatoid arthritis outcome: the role of maternofetal HLA class II disparity, Jt Bone Spine Rev Rhum, vol.77, issue.1, pp.36-40, 2010. ,
Smoking is a major preventable risk factor for Rheumatoid arthritis Estimations of risks after various exposures to cigarette smoke, Ann Rheum Dis, vol.70, issue.3, pp.508-511, 2011. ,
Tobacco Smoke Augments Porphyromonas gingivalis -Streptococcus gordonii Biofilm Formation, PLoS ONE, vol.6, issue.11, 2011. ,
, Ite : Pol a th ite rhumatoïde, Collège Français des Enseignants en Rhumatologie (COFER), 2011.
, , 2016.
le de l a gi ase da s la pol a th ite hu atoïde. Etude i i o hez le at, 2009. ,
D sfo tio e doth liale et pol a th ite hu atoïde : i ti ue d olutio , mécanismes et traitements. Etude chez le rat, 2015. ,
Pla e de l ta e ept da s la p ise e ha ge de la pol a th ite hu atoïde, 2014. ,
Rheumatoid arthritis, Nat Rev Dis Primer, vol.4, p.18001, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01558198
When does rheumatoid disease start?, Arthritis Rheum, vol.28, issue.5, pp.485-489, 1985. ,
Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis, Arthritis Rheum, vol.48, issue.10, pp.2741-2749, 2003. ,
Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative, Ann Rheum Dis, vol.69, issue.9, pp.1580-1588, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-01557559
Update of French society for rheumatology recommendations for managing rheumatoid arthritis. Jt Bone Spine Rev Rhum, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-02264783
EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis, Ann Rheum Dis, vol.69, issue.2, pp.325-331, 2010. ,
Progression in early rheumatoid arthritis, Best Pract Res Clin Rheumatol, vol.23, issue.1, pp.59-69, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-01558208
Que nous ont apporté les premières an es d tudes d u e oho te de polyarthrites rhumatoïdes débutantes : la cohorte ESPOIR ?, Rev Rhum, vol.81, issue.6, pp.455-459, 2014. ,
Pla e de l hog aphie da s la pol a th ite hu atoïde e issio ,
, Rev Rhum Monogr, vol.82, issue.4, pp.225-232, 2015.
MR imaging of the hands in rheumatoid arthritis, J Radiol, vol.91, issue.1, pp.111-119, 2010. ,
Lésions Des Poignets et Des Mains, 2015. ,
, , 2011.
Pol a th ite hu atoïde, P' ; attei te de l a a t-pied, 2011. ,
Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis, Arthritis Rheum, vol.38, issue.1, pp.44-48, 1995. ,
Les it es d aluatio de la polyarthrite rhumatoïde, Rev Marocaine Rhumatol, issue.19, pp.19-23, 2012. ,
A simplified disease activity index for rheumatoid arthritis for use in clinical practice, Rheumatol Oxf Engl, vol.42, issue.2, pp.244-257, 2003. ,
Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score, Arthritis Res Ther, vol.7, issue.4, pp.796-806, 2005. ,
The Stanford Health Assessment Questionnaire: Dimensions and Practical Applications, Health Qual Life Outcomes, vol.1, p.20, 2003. ,
Anti-arthritic agents: Progress and potential, Bioorg Med Chem, vol.23, issue.13, pp.3059-3080, 2015. ,
Rheumatoid Arthritis: A Brief Overview of the Treatment, Med Princ Pract Int J Kuwait Univ Health Sci Cent, 2018. ,
Diagnosis and Management of Rheumatoid Arthritis: A Review, JAMA, vol.320, issue.13, pp.1360-1372, 2018. ,
2016 update of the EULAR recommendations for the management of early arthritis, Ann Rheum Dis, vol.76, issue.6, pp.948-959, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01794370
Comparison of the long-term outcome for patients with rheumatoid arthritis with persistent moderate disease activity or disease remission during the first year after diagnosis: data from the ESPOIR cohort, Ann Rheum Dis, vol.74, issue.4, pp.724-729, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01044967
Cardiovascular co-morbidity in patients with rheumatoid arthritis: a narrative review of risk factors, cardiovascular risk assessment and treatment, BMC Rheumatol, vol.2, issue.1, p.10, 2018. ,
The occurrence of subclinical and clinical atherosclerosis in rheumatoid arthritis, results from the 3-year, multicenter, prospective, observational, GIRRCS study, Annals of Rheumatic Diseases, vol.78, pp.117-118 ,
Aiming for SDAI remission versus low disease activity at 1 year after inclusion in ESPOIR cohort is associated with better 3-year structural outcomes, Ann Rheum Dis, vol.74, issue.9, pp.1676-1683, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01032092
Non-drug treatment (excluding surgery) in rheumatoid arthritis: clinical practice guidelines, Jt Bone Spine Rev Rhum, vol.76, issue.6, pp.691-698, 2009. ,
The Role of Statins in Disease Modification and Cardiovascular Risk in Rheumatoid Arthritis, Front Med, vol.5, 2018. ,
Effect of atorvastatin on inflammation and modification of vascular risk factors in rheumatoid arthritis, J Rheumatol, vol.38, issue.2, pp.229-235, 2011. ,
Effects of rosuvastatin on subclinical atherosclerosis and arterial stiffness in rheumatoid arthritis: a randomized controlled pilot trial, Scand J Rheumatol, vol.40, issue.6, pp.411-421, 2011. ,
Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis, Circulation, vol.117, issue.17, pp.2262-2269, 2008. ,
Evaluation of the effect of losartan and methotrexate combined therapy in adjuvant-induced arthritis in rats, Eur J Pharmacol, vol.698, issue.1-3, pp.421-428, 2013. ,
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers, Arthritis Rheum, vol.62, issue.5, pp.1319-1328, 2010. ,
Physical activity and rheumatoid arthritis, a systematic review, Ann Rheum Dis, vol.74, issue.Suppl2, p.416, 2015. ,
, Dysfonction endothéliale et risque a dio as ulai e. L e e i e p ot ge la fo tio e doth liale et prévient la maladie cardiovasculaire, vol.24, pp.63-73, 2009.
Vascular function and inflammation in rheumatoid arthritis: the role of physical activity, Open Cardiovasc Med J, vol.4, pp.89-96, 2010. ,
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update, Ann Rheum Dis, vol.76, issue.6, pp.960-977, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01778213
American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis, Arthritis Rheumatol Hoboken NJ, vol.68, issue.1, pp.1-26, 2015. ,
Length of Life and Cause of Death in Rheumatoid Arthritis, N Engl J Med, vol.249, issue.14, pp.553-556, 1953. ,
Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies, Arthritis Rheum, vol.59, issue.12, pp.1690-1697, 2008. ,
Mortality in rheumatoid arthritis over the last fifty years: Systematic review and meta-analysis, Joint Bone Spine, vol.80, issue.1, pp.29-33, 2013. ,
EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update, Ann Rheum Dis, pp.2016-209775, 2016. ,
Cardiovascular and Metabolic Comorbidities in Rheumatoid Arthritis, Curr Rheumatol Rep, vol.20, issue.12, p.81, 2018. ,
The risk of myocardial infarction in rheumatoid arthritis and diabetes mellitus: a Danish nationwide cohort study, Ann Rheum Dis, vol.70, issue.6, pp.929-934, 2011. ,
Rheumatoid arthritis versus diabetes as a risk factor for cardiovascular disease: a cross-sectional study, the CARRE Investigation, Ann Rheum Dis, vol.68, issue.9, pp.1395-1400, 2009. ,
Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study, Arthritis Rheum, vol.61, issue.11, pp.1571-1579, 2009. ,
Is Rheumatoid Arthritis a Cardiovascular Risk Equivalent to Diabetes? Arthritis Care Res, 2018. ,
Cardiovascular Event Risk in Rheumatoid Arthritis is Higher than in Type 2 Diabetes: a 15 Year Longitudinal Study, J Rheumatol, 2019. ,
The influence of age at symptom onset and length of followup on mortality in patients with recent-onset inflammatory polyarthritis, Arthritis Rheum, vol.58, issue.4, pp.985-989, 2008. ,
How early is the atherosclerotic risk in rheumatoid arthritis?, Autoimmun Rev, vol.9, issue.10, pp.701-707, 2010. ,
How early in the course of rheumatoid arthritis does the excess cardiovascular risk appear?, Ann Rheum Dis, vol.71, issue.10, pp.1606-1615, 2012. ,
Excess mortality emerges after 10 years in an inception cohort of early rheumatoid arthritis, Arthritis Care Res, vol.62, issue.3, pp.362-370, 2010. ,
The effect of disease duration and disease activity on the risk of cardiovascular disease in rheumatoid arthritis patients, Ann Rheum Dis, vol.74, issue.6, pp.998-1003, 2014. ,
The role of rheumatoid arthritis (RA) flare and cumulative burden of RA severity in the risk of cardiovascular disease, Ann Rheum Dis, vol.75, issue.3, pp.560-565, 2016. ,
Cause-Specific Mortality in Male US Veterans With Rheumatoid Arthritis, Arthritis Care Res, vol.68, issue.1, pp.36-45, 2016. ,
Improvement in 5-year mortality in incident rheumatoid arthritis compared with the general population-closing the mortality gap, Ann Rheum Dis, vol.76, issue.6, pp.1057-1063, 2017. ,
Disease Activity in Rheumatoid Arthritis and the Risk of Cardiovascular Events, Arthritis Rheumatol, vol.67, issue.6, pp.1449-1455, 2015. ,
Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies, Ann Rheum Dis, vol.71, issue.9, pp.1524-1529, 2012. ,
The effect of rheumatoid arthritis on the risk of cerebrovascular disease and coronary artery disease in young adults, J Chin Med Assoc JCMA, vol.81, issue.9, pp.772-780, 2018. ,
High risk of clinical cardiovascular events in rheumatoid arthritis: Levels of associations of myocardial infarction and stroke through a systematic review and meta-analysis, Arch Cardiovasc Dis, vol.103, issue.4, pp.253-261, 2010. ,
Coronary microvascular dysfunction in chronic inflammatory rheumatoid diseases, Eur Heart J, vol.37, issue.23, pp.1799-1806, 2016. ,
Update on Cardiovascular Disease Risk in Patients with Rheumatic Diseases, Rheum Dis Clin North Am, vol.44, issue.3, pp.475-487, 2018. ,
Rheumatoid arthritis and risk of cardiovascular disease, Cardiovasc J Afr, vol.29, issue.5, pp.317-321, 2018. ,
Heart Involvement in Inflammatory Rheumatic Diseases: A Systematic Literature Review, Med Kaunas Lith, vol.55, issue.6, 2019. ,
No increased occurrence of ischemic heart disease prior to the onset of rheumatoid arthritis: results from two Swedish populationbased rheumatoid arthritis cohorts, Arthritis Rheum, vol.60, issue.10, pp.2861-2869, 2009. ,
Rapid increase in myocardial infarction risk following diagnosis of rheumatoid arthritis amongst patients diagnosed between 1995 and 2006, J Intern Med, vol.268, issue.6, pp.578-585, 2010. ,
Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England, PloS One, vol.11, issue.3, p.151245, 2016. ,
Risk Factors for the Rapid Increase in Risk of Acute Coronary Events in Patients With New-Onset Rheumatoid Arthritis: A Nested Case-Control Study, Arthritis Rheumatol, vol.67, issue.11, pp.2845-2854, 2015. ,
Features of cardiac remodeling in Patients with Acute Coronary Syndrome Complicated with Rheumatoid Arthritis, Sci Rep, vol.7, 2017. ,
The risk of congestive heart failure in rheumatoid arthritis: a population-based study over 46 years, Arthritis Rheum, vol.52, issue.2, pp.412-420, 2005. ,
Development of heart failure in patients with rheumatoid arthritis: A Danish population-based study, Eur J Clin Invest, vol.48, issue.5, p.12915, 2018. ,
Central role of RIPK1-VDAC1 pathway on cardiac impairment in a non-human primate model of rheumatoid arthritis, J Mol Cell Cardiol, vol.125, pp.50-60, 2018. ,
The presentation and outcome of heart failure in patients with rheumatoid arthritis differs from that in the general population, Arthritis Rheum, vol.58, issue.9, pp.2603-2611, 2008. ,
Diastolic dysfunction in rheumatoid arthritis: a meta-analysis and systematic review, Arthritis Care Res, vol.65, issue.4, pp.534-543, 2013. ,
Brief report: rheumatoid arthritis is associated with left ventricular concentric remodeling: results of a population-based cross-sectional study, Arthritis Rheum, vol.65, issue.7, pp.1713-1718, 2013. ,
Disease activity and left ventricular structure in patients with rheumatoid arthritis, Rheumatology, vol.54, issue.3, pp.511-519, 2015. ,
Disease activity is associated with reduced left ventricular systolic myocardial function in patients with rheumatoid arthritis, Ann Rheum Dis, vol.76, issue.2, pp.371-376, 2017. ,
Myocardial Inflammation, Measured Using 18-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG PET-CT) is Associated with Disease Activity in Rheumatoid Arthritis. Arthritis Rheumatol Hoboken NJ, 2018. ,
Magnetic Resonance Imaging-Detected Myocardial Inflammation and Fibrosis in Rheumatoid Arthritis: Associations With Disease Characteristics and N-Terminal Pro-Brain Natriuretic Peptide Levels, Arthritis Care Res, vol.69, issue.9, pp.1304-1311, 2017. ,
t?p iak B. Ca dio as ula s ste ha ges i rheumatoid arthritis patients with continued low disease activity, Rheumatol Int, vol.38, issue.7, pp.1207-1215, 2018. ,
Diastoli d sfu tio i heu atoid arthritis patients with low disease activity, Clin Rheumatol, 2018. ,
Sudden cardiac death in patients with rheumatoid arthritis, World J Cardiol, vol.9, issue.7, pp.562-573, 2017. ,
Cardiovascular autonomic regulation, inflammation and pain in rheumatoid arthritis, Auton Neurosci, vol.208, pp.137-145, 2017. ,
,
, Ann Cardiol Angiol, vol.61, issue.2, pp.111-117, 2012.
Risk of subsequent ischemic and hemorrhagic stroke in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden, BMC Neurol, vol.12, p.41, 2012. ,
Cerebrovascular Disease in Rheumatic Diseases: A Systematic Review and Meta-Analysis, Stroke, vol.47, issue.4, pp.943-950, 2016. ,
Rheumatoid arthritis significantly increased recurrence risk after ischemic stroke/transient ischemic attack, J Neurol, vol.265, issue.8, pp.1810-1818, 2018. ,
Etiology of acute ischaemic cerebrovascular disease associated with rheumatoid arthritis: changes with progression of anti-inflammatory therapy, Eur J Neurol, vol.12, pp.1462-1469, 2018. ,
Association Between Ischemic Stroke and Tumor Necrosis Factor Inhibitor Therapy in Patients With Rheumatoid Arthritis, Arthritis Rheumatol Hoboken NJ, vol.68, issue.6, pp.1337-1345, 2016. ,
Vascular Cognitive Impairment, Circ Res, vol.120, issue.3, pp.573-591, 2017. ,
Brain-derived neurotrophic factor in adjuvantinduced arthritis in rats. Relationship with inflammation and endothelial dysfunction, Prog Neuropsychopharmacol Biol Psychiatry, vol.82, pp.249-254, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01706776
The Cerebral Brain-Derived Neurotrophic Factor Pathway, Either Neuronal or Endothelial, Is Impaired in Rats with Adjuvant-Induced Arthritis. Connection with Endothelial Dysfunction, Front Physiol, vol.8, p.1125, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01681219
Cognitive Impairment in Rheumatoid Arthritis: A Systematic Review, Arthritis Care Res, vol.70, issue.1, pp.39-52, 2018. ,
Are behaviour and motor performances of rheumatoid arthritis patients influenced by subclinical cognitive impairments? A clinical and neuroimaging study, Clin Exp Rheumatol, vol.20, issue.4, pp.491-497, 2002. ,
Cognitive impairment in rheumatoid arthritis, Methods Find Exp Clin Pharmacol, vol.26, issue.5, pp.339-343, 2004. ,
Cognitive Impairment in Persons With Rheumatoid Arthritis, Arthritis Care Res, vol.64, issue.8, pp.1144-1150, 2012. ,
Rheumatic diseases and autoimmune vascular dementia, Autoimmun Rev, vol.16, issue.12, pp.1265-1269, 2017. ,
Cognitive function of patients with rheumatoid arthritis is associated with disease activity but not carotid atherosclerotic changes, Clin Exp Rheumatol, vol.36, issue.5, pp.856-861, 2018. ,
Depression in patients with rheumatoid arthritis: description, causes and mechanisms, Int J Clin Rheumatol, vol.6, issue.6, pp.617-623, 2011. ,
The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis, Rheumatol Oxf Engl, vol.52, issue.12, pp.2136-2148, 2013. ,
Does depression increase the risk of stroke in patients with rheumatoid arthritis? A population-based cohort study, BMJ Open, vol.7, issue.4, p.14233, 2017. ,
Bipolar disorder associated with rheumatoid arthritis: A case-control study, J Affect Disord, vol.189, pp.287-289, 2016. ,
Vascular disease in rheumatoid arthritis: from subclinical lesions to cardiovascular risk, Eur J Intern Med, vol.20, issue.4, pp.348-354, 2009. ,
Awareness and perceived risk of cardiovascular disease among individuals living with rheumatoid arthritis is low: results of a systematic literature review, Arthritis Res Ther, vol.21, issue.1, p.33, 2019. ,
Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications, BMJ, vol.361, p.1036, 2018. ,
, European Society of Cardiology. SCORE Risk, 2016.
Usefulness of risk scores to estimate the risk of cardiovascular disease in patients with rheumatoid arthritis, Am J Cardiol, vol.110, issue.3, pp.420-424, 2012. ,
Performance of four current risk algorithms in predicting cardiovascular events in patients with early rheumatoid arthritis, Ann Rheum Dis, vol.74, issue.4, pp.668-674, 2015. ,
Prediction of cardiovascular risk in rheumatoid arthritis: performance of original and adapted SCORE algorithms, Ann Rheum Dis, vol.75, issue.4, pp.674-680, 2016. ,
Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis, Cardiol Res Pract, p.7689208, 2019. ,
Derivation and Internal Validation of an Expanded Cardiovascular Risk Prediction Score for Rheumatoid Arthritis: A Consortium of Rheumatology Researchers of North America Registry Study, Arthritis Rheumatol, vol.67, issue.8, pp.1995-2003, 2015. ,
Challenges of developing a cardiovascular risk calculator for patients with rheumatoid arthritis, PLOS ONE, vol.12, issue.3, p.174656, 2017. ,
The best cardiovascular risk calculator to predict carotid plaques in rheumatoid arthritis patients, Clin Rheumatol, vol.37, issue.9, pp.2373-2380, 2018. ,
Rheumatoid arthritis-specific cardiovascular risk scores are not superior to general risk scores: a validation analysis of patients from seven countries, Rheumatology, vol.56, issue.7, pp.1102-1110, 2017. ,
High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors, Arthritis Rheum, vol.44, issue.12, pp.2737-2745, 2001. ,
Cardiovascular risk in rheumatoid arthritis, Joint Bone Spine, vol.81, issue.4, pp.298-302, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01117207
Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis, Rheumatol Oxf Engl, vol.46, issue.9, pp.1477-1482, 2007. ,
Hypertension in rheumatoid arthritis, Rheumatol Oxf Engl, vol.47, issue.9, pp.1286-1298, 2008. ,
Link between traditional cardiovascular risk factors and inflammation in patients with early arthritis: results from a French multicenter cohort, Arthritis Care Res, vol.64, issue.6, pp.872-880, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01557749
A te ial h pe te sio assessed out-ofoffi e i a o te po a oho t of heu atoid a th itis patie ts f ee of a dio as ula disease is characterized by high prevalence, low awareness, poor control and increased vascular damage, Arthritis Res Ther, vol.15, issue.5, p.142, 2013. ,
The impact of traditional cardiovascular risk factors on cardiovascular outcomes in patients with rheumatoid arthritis: a systematic review and meta-analysis, PloS One, vol.10, issue.2, p.117952, 2015. ,
Increased Cardiovascular Events and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients: 1 Year Prospective Single Centre Study, PLOS ONE, vol.12, issue.1, p.170108, 2017. ,
Rheumatoid arthritis, cardiovascular disease and physical exercise: a systematic review, Rheumatol Oxf Engl, vol.47, issue.3, pp.239-248, 2008. ,
Arterial stiffness and arterial wave reflections are associated with systolic and diastolic function in patients with normal ejection fraction, Am J Hypertens, vol.21, issue.11, pp.1194-1202, 2008. ,
Systolic and diastolic function as related to arterial stiffness, Artery Res, vol.4, issue.4, pp.122-127, 2010. ,
Lipids in RA: What do they mean?, Curr Rheumatol Rep, vol.20, issue.2, p.8, 2018. ,
Lipid paradox in rheumatoid arthritis: the impact of serum lipid measures and systemic inflammation on the risk of cardiovascular disease, Ann Rheum Dis, vol.70, issue.3, pp.482-487, 2011. ,
Association of hyperlipidaemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration, Ann Rheum Dis, vol.75, issue.2, pp.341-347, 2016. ,
Systemic Inflammatory Response and Atherosclerosis: The Paradigm of Chronic Inflammatory Rheumatic Diseases, Int J Mol Sci, vol.19, issue.7, p.1890, 2018. ,
Athérome et polyarthrite rhumatoïde, Rev Médecine Interne, vol.27, pp.125-136, 2006. ,
Impact of Obesity and Adiposity on Inflammatory Markers in Patients With Rheumatoid Arthritis, Arthritis Care Res, vol.69, issue.12, pp.1789-1798, 2017. ,
Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats, Hypertension, vol.49, issue.4, pp.893-901, 2007. ,
Glucose tolerance, insulin sensitivity and ?cell function in patients with rheumatoid arthritis treated with or without low-to-medium dose glucocorticoids, Ann Rheum Dis, vol.70, issue.11, pp.1887-1894, 2011. ,
Rheumatoid Arthritis: A Disease Associated with Accelerated Atherogenesis, Semin Arthritis Rheum, vol.35, issue.1, pp.8-17, 2005. ,
Subclinical atherosclerosis in patients with rheumatoid arthritis. A meta-analysis of literature studies, Thromb Haemost, vol.113, issue.5, pp.916-930, 2015. ,
u li i al athe os le osis, carotid intima-media thickness and the cardiovascular risk, Romanian J Intern Med Rev Roum Med Interne, vol.41, issue.4, pp.357-363, 2003. ,
Sitzer Matthias. Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness, Circulation, vol.115, issue.4, pp.459-467, 2007. ,
Rheumatic disease and carotid intima-media thickness: a systematic review and meta-analysis ,
, Arterioscler Thromb Vasc Biol, vol.30, issue.5, pp.1014-1026, 2010.
Treat-to-target therapy does not prevent excessive progression of carotid intima media thickness during the first year of therapy in early rheumatoid arthritis, Arch Med Sci Atheroscler Dis, vol.1, issue.1, pp.36-43, 2016. ,
Ge de Diffe e es i Ca dio as ula Risk Profile in Rheumatoid Arthritis Patients with Low Disease Activity, BioMed Res Int, 2019. ,
Accelerated atherosclerosis in autoimmune rheumatic diseases, Circulation, vol.112, issue.21, pp.3337-3347, 2005. ,
168. del 'i I, F ee a GL, Haas 'W, O Lea DH, Es ala te A. 'elati e o t i utio of cardiovascular risk factors and rheumatoid arthritis clinical manifestations to atherosclerosis, Arthritis Rheum, vol.63, issue.5, pp.3413-3423, 2005. ,
Common atherosclerosis genetic risk factors and subclinical atherosclerosis in rheumatoid arthritis: the relevance of disease duration, Rheumatol Int, 2018. ,
Carotid Plaque Characteristics and Disease Activity in Rheumatoid Arthritis, J Rheumatol, vol.40, issue.4, pp.359-368, 2013. ,
Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factors, Arthritis Rheum, vol.52, issue.10, pp.3045-3053, 2005. ,
Arterial function in cardio-metabolic diseases: from the microcirculation to the large conduits, Prog Cardiovasc Dis, vol.57, issue.5, pp.489-496, 2015. ,
Relationship between arterial stiffness and cognitive function in elderly subjects with complaints of memory loss, Stroke, vol.36, issue.10, pp.2193-2197, 2005. ,
Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study, J Am Heart Assoc, vol.5, issue.5, 2016. ,
Pulse wave velocity and augmentation index are not independently associated with carotid atherosclerosis in patients with rheumatoid arthritis, Clin Rheumatol, vol.36, issue.11, pp.2601-2606, 2017. ,
Forearm haemodynamics, arterial stiffness and microcirculatory reactivity in rheumatoid arthritis, J Hypertens, vol.25, issue.6, pp.1273-1278, 2007. ,
Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapy, Circulation, vol.114, issue.11, pp.1185-1192, 2006. ,
Increased augmentation index in rheumatoid arthritis and its relationship to coronary artery atherosclerosis, J Rheumatol, vol.34, issue.12, pp.2388-2394, 2007. ,
C-reactive protein, fibrinogen, and cardiovascular disease prediction, N Engl J Med, vol.367, issue.14, pp.1310-1320, 2012. ,
HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritis, Arthritis Rheum, vol.57, issue.1, pp.125-132, 2007. ,
The association between inflammatory markers, serum lipids and the risk of cardiovascular events in patients with rheumatoid arthritis, Ann Rheum Dis, vol.73, issue.7, pp.1301-1308, 2014. ,
Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes, Trends Endocrinol Metab TEM, vol.11, issue.6, pp.212-217, 2000. ,
The pathogenesis of atherosclerosis in autoimmune rheumatic diseases: roles of inflammation and dyslipidemia, J Autoimmun, vol.28, issue.2-3, pp.69-75, 2007. ,
ste i i fla atio a d a dio as ula isk factors predict rapid progression of atherosclerosis in rheumatoid arthritis, Ann Rheum Dis, vol.74, issue.6, pp.1118-1123, 2015. ,
Interleukin-6 and insulin sensitivity: friend or foe?, Diabetologia, vol.47, issue.7, pp.1135-1142, 2004. ,
Ischemic heart disease and rheumatoid arthritis: Do inflammatory cytokines have a role?, Cytokine, vol.96, pp.228-233, 2017. ,
Impaired coronary microvascular function and increased intima-media thickness in rheumatoid arthritis, Atherosclerosis, vol.198, issue.2, pp.332-337, 2008. ,
Chronic Inflammatory Disease Is an Independent Risk Factor for Coronary Flow Velocity Reserve Impairment Unrelated to the Processes of Coronary Artery Calcium Deposition, J Am Soc Echocardiogr, vol.29, issue.2, pp.173-180, 2016. ,
Etanercept normalises left ventricular mass in patients with rheumatoid arthritis, Ann Rheum Dis, vol.72, issue.6, pp.881-887, 2013. ,
Increased Benefit of Interleukin 1 Inhibition on Vascular Function, Myocardial Deformation, and Twisting in Patients with Coronary Artery Disease and Coexisting Rheumatoid Arthritis, Circ Cardiovasc Imaging, vol.7, issue.4, pp.619-628, 2014. ,
Risk of Myocardial Infarction and Stroke after Acute Infection or Vaccination, N Engl J Med, vol.351, issue.25, pp.2611-2618, 2004. ,
Systematic Review and Meta-Analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke: an Update, Transl Stroke Res, vol.7, issue.5, pp.395-406, 2016. ,
, Stroke. Stroke, vol.47, issue.8, pp.2160-2167, 2016.
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction, vol.55, pp.500-507, 1979. ,
Interleukin-17 in post-stroke neurodegeneration, Neurosci Biobehav Rev, vol.37, issue.3, pp.436-447, 2013. ,
Rheumatoid arthritis and depression: an inflammatory perspective, Lancet Psychiatry, vol.6, issue.2, pp.30255-30259, 2019. ,
The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis, Ann Rheum Dis, vol.74, issue.3, pp.480-489, 2015. ,
Methotrexate might reduce ischemic stroke in patients with rheumatoid arthritis: a population-based retrospective cohort study, Int J Rheum Dis, vol.21, issue.8, pp.1591-1599, 2018. ,
The Impact of Targeted Rheumatoid Arthritis Pharmacologic Treatment on Mental Health: A Systematic Review and Network Meta-Analysis, Arthritis Rheumatol, vol.70, issue.9, pp.1377-1391, 2018. ,
Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway, Br J Pharmacol, vol.165, issue.2, pp.506-519, 2012. ,
Impact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis, Ann Rheum Dis, vol.77, issue.1, pp.48-54, 2018. ,
Atherosclerosis in rheumatoid arthritis: is it all about inflammation?, Nat Rev Rheumatol, vol.11, issue.7, pp.390-400, 2015. ,
Targeting Inflammation to Prevent Cardiovascular Disease in Chronic Rheumatic Diseases: Myth or Reality? Front Cardiovasc Med, vol.5, 2018. ,
Newly identified antiatherosclerotic activity of methotrexate and adalimumab: complementary effects on lipoprotein function and macrophage cholesterol metabolism, Arthritis Rheumatol Hoboken NJ, vol.67, issue.5, pp.1155-1164, 2015. ,
High-density lipoprotein cholesterol efflux capacity is inversely associated with cardiovascular risk: a systematic review and meta-analysis, Lipids Health Dis, vol.16, issue.1, p.212, 2017. ,
Adenosine abolishes MTX-induced suppression of osteoclastogenesis and inflammatory bone destruction in adjuvant-induced arthritis, Lab Investig J Tech Methods Pathol, vol.91, issue.5, pp.719-731, 2011. ,
Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation, Ann Rheum Dis, 2015. ,
B?l? es u "M. Ca dio as ula effe ts of methotrexate in immune-mediated inflammatory diseases, Exp Ther Med, vol.17, issue.2, pp.1024-1029, 2019. ,
Cardiovascular effects of hydroxychloroquine: a systematic review and meta-analysis, Ann Rheum Dis, vol.77, issue.10, p.65, 2018. ,
The effect of TNF-a antagonists on aortic stiffness and wave reflections: a meta-analysis, Clin Rheumatol, vol.37, issue.2, pp.515-526, 2018. ,
Anti-TNF modulation reduces myocardial inflammation and improves cardiovascular function in systemic rheumatic diseases, Int J Cardiol, vol.270, pp.253-259, 2018. ,
Effect of TNF inhibitors on lipid profile in rheumatoid arthritis: a systematic review with meta-analysis, Ann Rheum Dis, vol.71, issue.6, pp.862-868, 2012. ,
Improved insulin sensitivity by anti-TNFalpha antibody treatment in patients with rheumatic diseases, Ann Rheum Dis, vol.66, issue.4, pp.558-559, 2007. ,
Anti-tumor necrosis factor-alpha antibody limits heart failure in a transgenic model, Circulation, vol.104, issue.10, pp.1094-1097, 2001. ,
Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL), Circulation, vol.109, issue.13, pp.1594-1602, 2004. ,
Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial, Circulation, vol.107, issue.25, pp.3133-3140, 2003. ,
Tumour Necrosis Factor-? Inhibition Improves Stroke Outcome in a Mouse Model of Rheumatoid Arthritis, Sci Rep, vol.9, 2019. ,
Tumor Necrosis Factor Inhibitor Therapy and the Risk for Depression Among Working-Age Adults with Rheumatoid Arthritis, Am Health Drug Benefits, vol.12, issue.1, pp.30-38, 2019. ,
Lipid profile changes in patients with chronic inflammatory arthritis treated with biologic agents and tofacitinib in randomized clinical trials: a systematic review and meta-analysis, Arthritis Rheumatol Hoboken NJ, vol.67, issue.1, pp.117-127, 2015. ,
Comparison of lipid and lipid-associated cardiovascular risk marker changes after treatment with tocilizumab or adalimumab in patients with rheumatoid arthritis, Ann Rheum Dis, vol.75, issue.10, pp.1806-1812, 2016. ,
Cardiovascular Safety of Tocilizumab Versus Tumor Necrosis Factor Inhibitors in Patients With Rheumatoid Arthritis: A Multi-Database Cohort Study, Arthritis Rheumatol, vol.69, issue.6, pp.1154-1164, 2017. ,
Tocilizumab improves the proatherothrombotic profile of rheumatoid arthritis patients modulating endothelial dysfunction, NETosis, and inflammation, Transl Res, vol.183, pp.87-103, 2017. ,
Tocilizumab modulates serum levels of adiponectin and chemerin in patients with rheumatoid arthritis: potential cardiovascular protective role of IL-6 inhibition, Clin Exp Rheumatol, 2018. ,
Tocilizumab Monotherapy Reduces Arterial Stiffness as Effectively as Etanercept or Adalimumab Monotherapy in Rheumatoid Arthritis: An Open-label Randomized Controlled Trial, J Rheumatol, vol.38, issue.10, pp.2169-2171, 2011. ,
Effects of 6 months of abatacept treatment on aortic stiffness in patients with rheumatoid arthritis, Biol Targets Ther, vol.7, pp.259-264, 2013. ,
The Effects of Rituximab on Lipids, Arterial Stiffness and Carotid Intima-Media Thickness in Rheumatoid Arthritis, J Korean Med Sci, vol.31, issue.2, pp.202-207, 2016. ,
Effects of rituximab treatment on endothelial dysfunction, carotid atherosclerosis, and lipid profile in rheumatoid arthritis, Clin Rheumatol, vol.28, issue.6, pp.705-710, 2009. ,
No significant change in arterial stiffness in RA after 6 months and 1 year of rituximab treatment, Rheumatol Oxf Engl, vol.51, issue.6, pp.1107-1111, 2012. ,
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis, N Engl J Med, vol.367, issue.6, pp.508-519, 2012. ,
Tofacitinib improves atherosclerosis despite upregulating serum cholesterol in patients with active rheumatoid arthritis: a cohort study, Rheumatol Int, vol.37, issue.12, pp.2079-2085, 2017. ,
Baricitinib induces LDL-C and HDL-C increases in rheumatoid arthritis: a meta-analysis of randomized controlled trials, Lipids Health Dis, vol.18, issue.1, p.54, 2019. ,
Impact of Janus kinase inhibitors on risk of cardiovascular events in patients with rheumatoid arthritis: systematic review and metaanalysis of randomised controlled trials, Ann Rheum Dis, 2019. ,
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis, N Engl J Med, vol.375, issue.26, pp.2519-2529, 2016. ,
Non-steroidal anti-inflammatory drugs and risk of cardiovascular disease in patients with rheumatoid arthritis: a nationwide cohort study, Ann Rheum Dis, vol.73, issue.8, pp.1515-1521, 2014. ,
Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients With Rheumatoid Arthritis, Am J Cardiol, vol.121, issue.10, pp.1271-1277, 2018. ,
, New safety advice for diclofenac -CMDh endorses PRAC recommendation, 2018.
, PRAC recommends updating advice on use of high-dose ibuprofen | European Medicines Agency
Glucocorticoid dose thresholds associated with all-cause and cardiovascular mortality in rheumatoid arthritis, Arthritis Rheumatol Hoboken NJ, vol.66, issue.2, pp.264-272, 2014. ,
Comparative effects of biologics on cardiovascular risk among older patients with rheumatoid arthritis, Ann Rheum Dis, vol.75, issue.10, pp.1813-1818, 2016. ,
Glucocorticoids and cardiovascular events in rheumatoid arthritis: a population-based cohort study, Arthritis Rheum, vol.56, issue.3, pp.820-830, 2007. ,
The biological role of inflammation in atherosclerosis, Can J Cardiol, vol.28, issue.6, pp.631-641, 2012. ,
Cardiovascular Outcomes Associated with Lowering Lowdensity Lipoprotein Cholesterol in Rheumatoid Arthritis and Matched Nonrheumatoid Arthritis, J Rheumatol, vol.43, issue.11, pp.1989-1996, 2016. ,
Trial of atorvastatin for the primary prevention of cardiovascular events in patients with rheumatoid arthritis (TRACE RA): A multicenter, randomized, placebo controlled trial. Arthritis Rheumatol Hoboken NJ, 2019. ,
Impact of statin discontinuation on mortality in patients with rheumatoid arthritis: A population-based study, Arthritis Care Res, vol.64, issue.6, pp.809-816, 2012. ,
Effects of high-dose atorvastatin on antiinflammatory properties of high density lipoprotein in patients with rheumatoid arthritis: a pilot study, J Rheumatol, vol.34, issue.7, pp.1459-1464, 2007. ,
Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study, Diabetes Care, vol.32, issue.6, pp.1087-1091, 2009. ,
Rosuvastatin-Induced Carotid Plaque Regression in Patients With Inflammatory Joint Diseases: The Rosuvastatin in Rheumatoid Arthritis, Ankylosing Spondylitis and Other Inflammatory Joint Diseases Study, Arthritis Rheumatol, vol.67, issue.7, pp.1718-1728, 2015. ,
Sustained Improvement of Arterial Stiffness and Blood Pressure after Long-Term Rosuvastatin Treatment in Patients with Inflammatory Joint Diseases: Results from the RORA-AS Study, PLOS ONE, vol.11, issue.4, p.153440, 2016. ,
Fluvastatin reverses endothelial dysfunction and increased vascular oxidative stress in rat adjuvant-induced arthritis, Arthritis Rheum, vol.56, issue.6, pp.1827-1835, 2007. ,
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein, N Engl J Med, vol.359, issue.21, pp.2195-2207, 2008. ,
Changes in lipoproteins associated with methotrexate or combination therapy in early rheumatoid arthritis: results from the treatment of early rheumatoid arthritis trial, Arthritis Rheum, vol.65, issue.6, pp.1430-1438, 2013. ,
Are Lipid Ratios Less Susceptible to Change With Systemic Inflammation Than Individual Lipid Components in Patients With Rheumatoid Arthritis?, Angiology, vol.62, issue.2, pp.167-175, 2011. ,
The interplay between inflammation, lipids and cardiovascular risk in rheumatoid arthritis: why ratios may be better, Int J Clin Pract, vol.64, issue.10, pp.1440-1443, 2010. ,
Association of Light-Intensity Physical Activity With Lower Cardiovascular Disease Risk Burden in Rheumatoid Arthritis, Arthritis Care Res, vol.68, issue.4, pp.424-431, 2016. ,
Individualised exercise improves endothelial function in patients with rheumatoid arthritis, Ann Rheum Dis, vol.73, issue.4, pp.748-751, 2014. ,
Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis, Ann Rheum Dis, vol.72, issue.11, pp.1819-1825, 2013. ,
Prognostic Value of Flow-Mediated Vasodilation in Brachial Artery and Fingertip Artery for Cardiovascular Events: A Systematic Review and Meta-Analysis, J Am Heart Assoc, vol.4, issue.11, 2015. ,
Endothelial Dysfunction as a Target for Prevention of Cardiovascular Disease, Diabetes Care, vol.32, issue.2, pp.314-321, 2009. ,
Endothelial dysfunction in joint disease, Joint Bone Spine, vol.81, issue.5, pp.386-391, 2014. ,
Anatomie et Physiologie Humaines. 4e édition. ERPI -Le Renouveau Pédagogique Editions, 2013. ,
Diversity in unity: The biochemical composition of the endothelial cell surface varies between the vascular beds, Microsc Res Tech, vol.57, issue.5, pp.381-389, 2002. ,
Microvascular dysfunction: a potential pathophysiological role in the metabolic syndrome. Hypertens Dallas Tex, vol.50, pp.204-211, 1979. ,
Physiology of the endothelium, Br J Anaesth, vol.93, issue.1, pp.105-113, 2004. ,
Mechanisms of endothelial dysfunction in rheumatoid arthritis: lessons from animal studies, Arthritis Res Ther, vol.16, issue.1, p.202, 2014. ,
Endothelial dysfunction and vascular disease -a 30th anniversary update, Acta Physiol Oxf Engl, vol.219, issue.1, pp.22-96, 2017. ,
Bios th se du o o de d azote NON : a is e, régulation et contrôle, Médecin/Sciences, vol.14, issue.11, pp.1185-1195, 1998. ,
Regulation of the monomer-dimer equilibrium in inducible nitric-oxide synthase by nitric oxide, J Biol Chem, vol.281, issue.12, pp.8197-8204, 2006. ,
Molecular mechanisms of endothelial NO synthase uncoupling, Curr Pharm Des, vol.20, issue.22, pp.3548-3553, 2014. ,
Prostacyclin among prostanoids, Pharmacol Rep PR, vol.60, issue.1, pp.3-11, 2008. ,
Prostacyclin in vascular diseases. -Recent insights and future perspectives, Circ J Off J Jpn Circ Soc, vol.74, issue.5, pp.836-843, 2010. ,
Endothelium-derived hyperpolarising factors and associated pathways: a synopsis, Pflüg Arch Eur J Physiol, vol.459, issue.6, pp.863-879, 2010. ,
Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms, Circ Res, vol.100, issue.2, pp.158-173, 2007. ,
Phenotypic heterogeneity of the endothelium: II. Representative vascular beds, Circ Res, vol.100, issue.2, pp.174-190, 2007. ,
Endothelium-derived hyperpolarizing factor in vascular physiology and cardiovascular disease, Atherosclerosis, vol.202, issue.2, pp.330-344, 2009. ,
Partie I -Physiologie cardio-i ulatoi e ; Chapit e -Physiologie de la circulation coronaire, Physiologie Humaine Appliquée. 2ème. Arnette, vol.2017, pp.83-88 ,
Nitric oxide exerts feedback inhibition on EDHFinduced coronary arteriolar dilation in vivo, Am J Physiol Heart Circ Physiol, vol.279, issue.2, pp.459-465, 2000. ,
In vivo location and mechanism of EDHF-mediated vasodilation in canine coronary microcirculation, Am J Physiol, vol.277, issue.3, pp.1252-1259, 1999. ,
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade, J Clin Invest, vol.95, issue.1, pp.285-295, 1995. ,
La physiologie de la circulation cérébrale, Bull Académie Vét Fr, vol.157, issue.3, pp.19-30, 2004. ,
Morgan & Claypool Life Sciences, 2009. ,
, Physiologie Humaine Appliquée. 2ème. Arnette, vol.2017, pp.627-643
Circle Of Willis: Anatomy, Diag a A d Fu tio s, ie e ABC. Sci ABC, 2017. ,
Morphology of cerebral arteries, Pharmacol Ther, vol.66, issue.1, pp.149-173, 1995. ,
Nitric oxide and the cerebral circulation, Stroke, vol.25, issue.3, pp.692-703, 1994. ,
Regulation of Cerebral Blood Flow, International Journal of Vascular Medicine ,
Physiological roles and properties of potassium channels in arterial smooth muscle, Am J Physiol, vol.268, issue.4, pp.799-822, 1995. ,
Direct modulation of Ca2+-activated K+ current by H-89 in rabbit coronary arterial smooth muscle cells, Vascul Pharmacol, vol.46, issue.2, pp.105-113, 2007. ,
Effects of increased intracranial pressure on cerebral blood volume, blood flow, and oxygen utilization in monkeys, J Neurosurg, vol.43, issue.4, pp.385-398, 1975. ,
Impaired Responsiveness to NO in Newly Diagnosed Patients With Rheumatoid Arthritis, Arterioscler Thromb Vasc Biol, vol.22, issue.10, pp.1637-1641, 2002. ,
Correlation between endothelial function and carotid atherosclerosis in rheumatoid arthritis patients with long-standing disease, Arthritis Res Ther, vol.13, issue.3, p.101, 2011. ,
Endothelial dysfunction in rat adjuvantinduced arthritis: up-regulation of the vascular arginase pathway, Arthritis Rheum, vol.63, issue.8, pp.2309-2317, 2011. ,
Endothelial dysfunction in rheumatic autoimmune diseases, Atherosclerosis, vol.224, issue.2, pp.309-317, 2012. ,
Vascular function and morphology in rheumatoid arthritis: a systematic review, Semin Arthritis Rheum, vol.50, issue.11, pp.669-675, 2011. ,
Vascular function and handgrip strength in rheumatoid arthritis patients, ScientificWorldJournal, p.580863, 2012. ,
Subendocardial viability ratio in patients with rheumatoid arthritis: comparison with healthy controls and identification of prognostic factors, Clin Rheumatol, vol.36, issue.6, pp.1229-1236, 2017. ,
Assessment of intracranial vessels in association with carotid atherosclerosis and brain vascular lesions in rheumatoid arthritis, Arthritis Res Ther, vol.19, issue.1, p.213, 2017. ,
The role of endothelial function and its assessment in rheumatoid arthritis, Nat Rev Rheumatol, vol.6, issue.5, pp.253-261, 2010. ,
The assessment of endothelial function: from research into clinical practice, Circulation, vol.126, issue.6, pp.753-767, 2012. ,
Isolated Vessels, Practical Methods in Cardiovascular Research, pp.198-211, 2005. ,
Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis, Circulation, vol.106, issue.17, pp.2184-2187, 2002. ,
Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity, Ann Rheum Dis, vol.63, issue.1, pp.31-35, 2004. ,
Evaluation of Endothelial Function by Flow-Mediated Dilation: a Comprehensive Review in Rheumatic Disease, Arch Immunol Ther Exp (Warsz), vol.65, issue.6, pp.463-475, 2017. ,
Clinical assessment of endothelial function in patients with rheumatoid arthritis: A meta-analysis of literature studies, Eur J Intern Med, vol.26, issue.10, pp.835-842, 2015. ,
Decreased flow-mediated dilatation in patients with rheumatoid arthritis: a meta-analysis, Postgrad Med J, vol.93, pp.260-265, 1099. ,
Endothelial function in rheumatoid arthritis, QJM Mon J Assoc Physicians, vol.111, issue.4, pp.243-247, 2018. ,
TNF-alpha blockade induces a reversible but transient effect on endothelial dysfunction in patients with long-standing severe rheumatoid arthritis, Clin Rheumatol, vol.27, issue.7, pp.833-839, 2008. ,
The influence of mean blood pressure on arterial stiffening and endothelial dysfunction in women with rheumatoid arthritis and systemic lupus erythematosus, Med Kaunas Lith, vol.46, issue.8, pp.522-530, 2010. ,
Impaired brachial artery flow-mediated dilation and increased carotid intima-media thickness in rheumatoid arthritis patients, Chin Med J (Engl), vol.125, issue.5, pp.832-837, 2012. ,
Inflammation and Microvascular and Macrovascular Endothelial Dysfunction in Rheumatoid Arthritis: Effect of Treatment, J Rheumatol, vol.37, issue.4, pp.711-716, 2010. ,
An observational study of endothelial function in early arthritis, Eur J Clin Invest, vol.42, issue.5, pp.510-516, 2012. ,
Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis, Arthritis Res Ther, vol.11, issue.2, p.51, 2009. ,
Paradoxical association of C-reactive protein with endothelial function in rheumatoid arthritis, PloS One, vol.5, issue.4, p.10242, 2010. ,
Effect of anti TNFalpha therapy on arterial diameter and wall shear stress and HDL cholesterol, Atherosclerosis, vol.177, issue.1, pp.113-118, 2004. ,
Endothelial dysfunction and atherosclerosis in rheumatoid arthritis: a multiparametric analysis using imaging techniques and laboratory markers of inflammation and autoimmunity, J Rheumatol, vol.35, issue.3, pp.398-406, 2008. ,
A pilot study of endothelial dysfunction and aortic stiffness after interleukin-6 receptor inhibition in rheumatoid arthritis, Atherosclerosis, vol.219, issue.2, pp.734-736, 2011. ,
Predictors of endothelial dysfunction in patients with rheumatoid arthritis, Angiology, vol.65, issue.9, pp.778-782, 2014. ,
Atherosclerosis in early rheumatoid arthritis: very early endothelial activation and rapid progression of intima media thickness, Arthritis Res Ther, vol.12, issue.4, p.158, 2010. ,
Decrease of asymmetric dimethyl arginine after anti-TNF therapy in patients with rheumatoid arthritis, Drug Dev Res, vol.75, issue.1, pp.67-69, 2014. ,
Atherosclerosis in rheumatoid arthritis versus diabetes: a comparative study, Arterioscler Thromb Vasc Biol, vol.29, issue.10, pp.1702-1708, 2009. ,
Epicardial adipose tissue thickness, flow-mediated dilatation of the brachial artery, and carotid intima-media thickness: Associations in rheumatoid arthritis patients, Herz, vol.40, issue.3, pp.217-224, 2015. ,
Screening for atherosclerosis in patients with rheumatoid arthritis: comparison of two in vivo tests of vascular function, Arthritis Rheum, vol.48, issue.1, pp.72-80, 2003. ,
Predictors of endothelial dysfunction and atherosclerosis in rheumatoid arthritis in Indian population, Indian Heart J, vol.69, issue.2, pp.200-206, 2017. ,
Carotid artery intima-media thickness and brachial artery flow-mediated vasodilatation in patients with rheumatoid arthritis, VASA Z Gefasskrankheiten, vol.41, issue.5, pp.343-351, 2012. ,
Surface expression of fractalkine receptor (CX3CR1) on CD4+/CD28 T cells in RA patients and correlation with atherosclerotic damage, Ann N Y Acad Sci, vol.1107, pp.32-41, 2007. ,
The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study, Arthritis Res Ther, vol.14, issue.3, p.117, 2012. ,
Clinical remission following treatment with tumour necrosis factor-alpha antagonists is not accompanied by changes in asymmetric dimethylarginine in patients with rheumatoid arthritis, Clin Biochem, vol.45, pp.1399-1403, 2012. ,
Inflammation, endothelial function and atherosclerosis in rheumatoid arthritis, Arthritis Res Ther, vol.14, issue.4, p.122, 2012. ,
Inflammation and atherosclerosis, Circulation, vol.105, issue.9, pp.1135-1143, 2002. ,
Classical cardiovascular disease risk factors associate with vascular function and morphology in rheumatoid arthritis: a six-year prospective study, Arthritis Res Ther, vol.15, issue.6, p.203, 2013. ,
Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation, Arthritis Rheum, vol.48, issue.1, pp.81-89, 2003. ,
Rheumatoid arthritis is sufficient to cause atheromatosis but not arterial stiffness or hypertrophy in the absence of classical cardiovascular risk factors, Clin Rheumatol, vol.34, issue.5, pp.853-859, 2015. ,
HLA-DRB1 status affects endothelial function in treated patients with rheumatoid arthritis, Am J Med, vol.114, issue.8, pp.647-652, 2003. ,
TNFA ? (rs1800629) polymorphism is associated with a higher risk of cardiovascular disease in patients with rheumatoid arthritis, Atherosclerosis, vol.216, issue.1, pp.125-130, 2011. ,
Interleukin-6 gene -174 promoter polymorphism is associated with endothelial dysfunction but not with disease susceptibility in patients with rheumatoid arthritis, Clin Exp Rheumatol, vol.27, issue.6, pp.964-970, 2009. ,
A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis, Arthritis Res Ther, vol.12, issue.2, p.71, 2010. ,
C allele of -786 T>C polymorphism in the promoter region of endothelial nitric oxide synthase is responsible for endothelial dysfunction in the patients with rheumatoid arthritis, J Cell Biochem, 2019. ,
Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis, Arthritis Res Ther, vol.7, issue.3, pp.634-643, 2005. ,
predictors of impaired endothelial function in rheumatoid arthritis patients, Scand J Rheumatol, vol.40, issue.6, pp.422-427, 2011. ,
Crosslinking of IgGs bound on circulating neutrophils leads to an activation of endothelial cells: possible role of rheumatoid factors in rheumatoid arthritis-associated vascular dysfunction, J Inflamm Lond Engl, vol.10, p.27, 2013. ,
Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis, Clin Chim Acta Int J Clin Chem, vol.455, pp.161-171, 2016. ,
Endothelial Dysfunction and Inflammation: Immunity in Rheumatoid Arthritis, Mediators Inflamm, p.6813016, 2016. ,
COX-1 and COX-2 tissue expression: implications and predictions, J Rheumatol Suppl, vol.49, pp.15-19, 1997. ,
Powerful inflammatory properties of large vein endothelium in vivo, Arterioscler Thromb Vasc Biol, vol.25, issue.4, pp.723-728, 2005. ,
Interleukin (IL)-33: new therapeutic target for atopic diseases, J Pharmacol Sci, vol.126, issue.2, pp.85-91, 2014. ,
New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis, Int J Mol Sci, vol.18, issue.10, 2017. ,
Effects of long-term disease-modifying antirheumatic drugs on endothelial function in patients with early rheumatoid arthritis, Cardiovasc Ther, vol.28, issue.5, pp.53-64, 2010. ,
Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis, Mediators of Inflammation ,
Ye ise Ç. 'elatio ship et ee as et i dimethylarginine and endothelial dysfunction in patients with rheumatoid arthritis, Eur J Rheumatol, vol.3, issue.3, pp.106-108, 2016. ,
Lack of association between asymmetric dimethylarginine and in vivo microvascular and macrovascular endothelial function in patients with rheumatoid arthritis, Clin Exp Rheumatol, vol.30, issue.3, pp.388-396, 2012. ,
In vivo microvascular and macrovascular endothelial function is not associated with circulating dimethylarginines in patients with rheumatoid arthritis: a prospective analysis of the DRACCO cohort, Scand J Clin Lab Invest, vol.76, issue.4, pp.331-337, 2016. ,
Association of Pentraxin 3 with Autoimmune Diseases: A Systematic Review and Meta-Analysis, Arch Med Res, vol.47, issue.3, pp.223-231, 2016. ,
Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis, PloS One, vol.12, issue.2, p.169830, 2017. ,
Mu a iu M. Vita i D "tatus, Disease A ti it , a d Endothelial Dysfunction in Early Rheumatoid Arthritis Patients, Dis Markers, p.5241012, 2017. ,
Assessment of subclinical atherosclerosis in psoriatic arthritis patients without clinically overt cardiovascular disease or traditional 199 ,
, atherosclerosis risk factors, vol.46, pp.358-365, 2018.
Free radicals and endothelial dysfunction: potential positive effects of TNF-? inhibitors, Redox Rep Commun Free Radic Res, vol.18, issue.3, pp.95-99, 2013. ,
The Effect of Treatments for Rheumatoid Arthritis on Endothelial Dysfunction Evaluated by Flow-Mediated Vasodilation in Patients with Rheumatoid Arthritis, Curr Vasc Pharmacol, vol.15, issue.1, pp.10-18, 2017. ,
Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: a systematic review and meta-analysis, Sci Rep, vol.7, issue.1, p.5346, 2017. ,
The effects of TNF-alpha inhibitor therapy on arterial stiffness and endothelial dysfunction in rheumatoid arthritis: a meta-analysis, Semin Arthritis Rheum, vol.43, issue.3, pp.1-2, 2013. ,
Sustained improvement of vascular endothelial function during anti-TNFalpha treatment in rheumatoid arthritis patients, Scand J Rheumatol, vol.38, issue.1, pp.6-10, 2009. ,
The Effect of Tumor Necrosis Factor-? Antagonists on Arterial Stiffness in Rheumatoid Arthritis: A Literature Review, Semin Arthritis Rheum, vol.42, issue.1, pp.1-8, 2012. ,
Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis, J Am Heart Assoc, vol.3, issue.5, p.1267, 2014. ,
Short-term improvement of endothelial function in rituximab-treated rheumatoid arthritis patients refractory to tumor necrosis factor alpha blocker therapy, Arthritis Rheum, vol.59, issue.12, pp.1821-1824, 2008. ,
Factors correlated with improvement of endothelial dysfunction during rituximab therapy in patients with rheumatoid arthritis, Biol Targets Ther, vol.7, pp.69-75, 2013. ,
Inhibition of interleukin-1 by anakinra improves vascular and left ventricular function in patients with rheumatoid arthritis, Circulation, vol.117, issue.20, pp.2662-2669, 2008. ,
Factors correlated with the improvement of endothelial dysfunction during Abatacept therapy in patients with rheumatoid arthritis, J Inflamm Res, vol.11, pp.247-252, 2018. ,
The impact of abatacept treatment on the vasculature in patients with rheumatoid arthritis, Clin Exp Rheumatol, vol.33, issue.4, p.589, 2015. ,
Glucocorticoids and endothelial function in inflammatory diseases: focus on rheumatoid arthritis, Arthritis Res Ther, vol.18, 2016. ,
Effects of selective and non-selective cyclo-oxygenase inhibition on endothelial function in patients with rheumatoid arthritis, Scand J Rheumatol, vol.36, issue.4, pp.265-269, 2007. ,
Ezetimibe and Simvastatin Reduce Inflammation, Disease Activity, and Aortic Stiffness and Improve Endothelial Function in Rheumatoid Arthritis, J Am Coll Cardiol, vol.50, issue.9, pp.852-858, 2007. ,
Effects of Angiotensin-converting enzyme inhibition and statin treatment on inflammatory markers and endothelial functions in patients with longterm rheumatoid arthritis, J Rheumatol, vol.32, issue.11, pp.2095-2101, 2005. ,
Vardenafil and cilostazol can improve vascular reactivity in rats with diabetes mellitus and rheumatoid arthritis co-morbidity, Life Sci, 2019. ,
Botta o A. A i al odels of heu atoid pai : experimental systems and insights, Arthritis Res Ther, vol.19, 2017. ,
Experimental animal models for rheumatoid arthritis, Immunopharmacol Immunotoxicol, vol.40, issue.3, pp.193-200, 2018. ,
Utility of animal models for identification of potential therapeutics for rheumatoid arthritis, Ann Rheum Dis, vol.67, issue.11, pp.1505-1515, 2008. ,
Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating Efficacy, Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating Efficacy, BioMed Res Int BioMed Res Int, p.569068, 2010. ,
Development of arthritis, periarthritis and periostitis in rats given adjuvants, Proc Soc Exp Biol Med Soc Exp Biol Med N Y N, vol.91, issue.1, pp.95-101, 1956. ,
Standardization of an experimental model suitable for studies on the effect of exercise on arthritis, Einstein São Paulo Braz, vol.11, issue.1, pp.76-82, 2013. ,
Collagen-induced arthritis and related animal models: how much of their pathogenesis is auto-immune, how much is auto-inflammatory?, Cytokine Growth Factor Rev, vol.22, issue.5-6, pp.339-344, 2011. ,
Collagen-induced arthritis as an animal model for rheumatoid arthritis: focus on interferon-?, J Interferon Cytokine Res Off J Int Soc Interferon Cytokine Res, vol.31, issue.12, pp.917-926, 2011. ,
Treatment with the arginase inhibitor Nw-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis, Arthritis Res Ther, vol.14, issue.3, p.130, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00727649
Endothelial Dysfunction in Rheumatoid Arthritis: Mechanistic Insights and Correlation with Circulating Markers of Systemic Inflammation, PloS One, vol.11, issue.1, p.146744, 2016. ,
2K1C-activated Angiotensin II (Ang II) exacerbates vascular damage in a rat model of arthritis through the ATR/ERK1/2 signaling pathway, Inflamm Res Off J Eur Histamine Res Soc Al, vol.66, issue.10, pp.881-890, 2017. ,
Collagen-induced arthritis increases inducible nitric oxide synthase not only in aorta but also in the cardiac and renal microcirculation of mice, Clin Exp Immunol, vol.183, issue.3, pp.341-349, 2016. ,
Microvascular Abnormalities in Adjuvant-Induced Arthritis: Relationship to Macrovascular Endothelial Function and Markers of Endothelial Activation, Arthritis Rheumatol, vol.67, issue.5, pp.1203-1213, 2015. ,
Endothelium-derived contraction in a model of rheumatoid arthritis is mediated via angiotensin II type 1 receptors, Vascul Pharmacol, vol.100, pp.51-57, 2018. ,
Etanercept improves endothelial function via pleiotropic effects in rat adjuvant-induced arthritis. Rheumatol Oxf Engl, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01376195
Glucocorticoids improve endothelial function in rheumatoid arthritis: a study in rats with adjuvant-induced arthritis, Clin Exp Immunol, vol.188, issue.2, pp.208-218, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01563702
Diclofenac but not celecoxib improves endothelial function in rheumatoid arthritis: A study in adjuvant-induced arthritis, Atherosclerosis, vol.266, pp.136-144, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01652245
Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis, Life Sci, vol.92, issue.23, pp.1131-1137, 2013. ,
Testing endothelial function and its clinical relevance, J Atheroscler Thromb, vol.20, issue.1, pp.1-8, 2013. ,
Endothelial dysfunction in conduit arteries and in microcirculation. Novel therapeutic approaches, Pharmacol Ther, vol.144, issue.3, pp.253-267, 2014. ,
Current concepts in assessment of microvascular endothelial function using laser Doppler imaging and iontophoresis, Trends Cardiovasc Med, vol.18, issue.4, pp.109-116, 2008. ,
Assessment of endothelial function by non-invasive peripheral arterial tonometry predicts late cardiovascular adverse events, Eur Heart J, vol.31, issue.9, pp.1142-1148, 2010. ,
Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia, J Am Coll Cardiol, vol.44, issue.11, pp.2137-2141, 2004. ,
Explorer la réserve coronaire par échocardiographie-Doppler transthoracique, Réal Cardiol, issue.292, pp.9-14, 2013. ,
Reduced Subendocardial Viability Ratio Is Associated With Unfavorable Cardiovascular Risk Profile in Women With Short Duration of Type 2 Diabetes, Am J Hypertens, vol.29, issue.10, pp.1165-1172, 2016. ,
Usefulness of Transcranial Doppler Ultrasound in Evaluating Cervical-Cranial Collateral Circulations, Interv Neurol, vol.2, issue.1, pp.8-18, 2013. ,
Application of Transcranial Color Doppler Ultrasonography for Assessing Middle Cerebral Arteries in Rheumatoid Arthritis, Ultrasound Q, vol.33, issue.4, pp.281-283, 2017. ,
Techniques to study the pharmacodynamics of isolated large and small blood vessels, J Pharmacol Toxicol Methods, vol.44, issue.2, pp.395-407, 2000. ,
Stimulation of ?2Adrenoceptors Dilates the Rat Middle Cerebral Artery, Anesthesiol J Am Soc Anesthesiol, vol.85, issue.1, pp.82-90, 1996. ,
In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound, Am J Physiol Heart Circ Physiol, vol.294, issue.2, pp.1086-1093, 2008. ,
Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo, Microvasc Res, vol.85, pp.86-92, 2013. ,
Microvascular endothelial dysfunction in rheumatoid arthritis, Nat Rev Rheumatol, vol.14, issue.7, pp.404-420, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01875778
Coronary flow reserve in systemic rheumatic diseases: a systematic review and meta-analysis, Rheumatol Int, vol.38, issue.7, pp.1179-1190, 2018. ,
The effect of non-TNF-targeted biologics on vascular dysfunction in rheumatoid arthritis: A systematic literature review, Autoimmun Rev, 2019. ,
Endothelial dysfunction in young patients with long-term rheumatoid arthritis and low disease activity, Atherosclerosis, vol.170, issue.1, pp.177-180, 2003. ,
Effects of disease modifying anti-rheumatic drugs on subclinical atherosclerosis and endothelial dysfunction which has been detected in early rheumatoid arthritis: 1-year follow-up study, Semin Arthritis Rheum, vol.43, issue.1, pp.48-54, 2013. ,
Pioglitazone ameliorates methotrexate-induced renal endothelial dysfunction via amending detrimental changes in some antioxidant parameters, systemic cytokines and Fas production, Vascul Pharmacol, vol.74, pp.139-150, 2015. ,
Curcumin and folic acid abrogated methotrexate induced vascular endothelial dysfunction, Can J Physiol Pharmacol, vol.94, issue.1, pp.89-96, 2016. ,
Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo, Am J Physiol Heart Circ Physiol, vol.301, issue.3, pp.721-729, 2011. ,
Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation, Circulation, vol.113, issue.24, pp.2818-2825, 2006. ,
Endothelial dysfunction and stroke, J Cardiovasc Pharmacol, vol.38, issue.2, pp.75-78, 2001. ,
Cerebral Vascular Disease and Neurovascular Injury in Ischemic Stroke, Circ Res, vol.120, issue.3, pp.449-471, 2017. ,
Arginase Inhibitors: A Rational Approach Over One Century, Med Res Rev, vol.37, issue.3, pp.475-513, 2017. ,
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis, Arthritis Res Ther, vol.20, issue.1, p.123, 2018. ,
Non-invasive assessment of coronary flow reserve and ADMA levels: a case-control study of early rheumatoid arthritis patients, Rheumatol Oxf Engl, vol.48, issue.7, pp.834-839, 2009. ,
Chronic inflammation and coronary microvascular dysfunction in patients without risk factors for coronary artery disease, Eur Heart J, vol.30, issue.15, pp.1837-1843, 2009. ,
Endothelial dysfunction in an ovine model of collagen-induced arthritis, J Vasc Res, vol.51, issue.2, pp.90-101, 2014. ,
Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis, Arthritis Res Ther, vol.14, issue.5, p.223, 2012. ,
Oxidative state and oxidative metabolism of the heart from rats with adjuvant-induced arthritis, Exp Mol Pathol, vol.100, issue.3, pp.393-401, 2016. ,
Effect of omega-3 on cardiac muscle structure in a model of rheumatoid arthritis in rat. A light and electron microscopic study, Eur J Pharm Med Res, vol.4, issue.8, pp.9-19, 2017. ,
Biological markers of oxidative stress: Applications to cardiovascular research and practice, Redox Biol, vol.1, issue.1, pp.483-491, 2013. ,
Myeloperoxidase: a new biomarker of inflammation in ischemic heart disease and acute coronary syndromes, Mediators Inflamm, p.135625, 2008. ,
Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis, Arthritis Res Ther, vol.7, issue.5, pp.195-207, 2005. ,
A signature of aberrant immune responsiveness identifies myocardial dysfunction in rheumatoid arthritis, Arthritis Rheum, vol.63, issue.6, pp.1497-1506, 2011. ,
The Development of Myocardial Fibrosis in Transgenic Mice with Targeted Overexpression of Tumor Necrosis Factor Requires Mast Cell-Fibroblast Interactions, Circulation, vol.124, pp.2106-2116, 2011. ,
oxidative stress and impaired contractility in a rheumatoid arthritis mouse model, Heart, vol.104, issue.24, pp.2026-2034, 2018. ,
Role of AT2 receptors in the cardioprotective effect of AT1 antagonists in mice. Hypertens Dallas Tex, vol.40, pp.244-250, 1979. ,
In vitro inhibition of HUVECs by low dose methotrexate -insights into oral adverse events, Head Face Med, vol.10, p.19, 2014. ,
Methotrexate Causes Apoptosis in Postmitotic Endothelial Cells, Biol Res Nurs, vol.2, issue.1, pp.5-14, 2000. ,
Methotrexate suppresses nitric oxide production ex vivo in macrophages from rats with adjuvant-induced arthritis, Res Exp Med Z Für Gesamte Exp Med Einschl Exp Chir, vol.197, issue.2, pp.81-90, 1997. ,
Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression, J Biol Chem, vol.284, issue.2, pp.1136-1144, 2009. ,
Direct activation of AMPactivated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells, J Biol Chem, vol.278, issue.34, pp.31629-31639, 2003. ,
Quantitative gait analysis as a method to assess mechanical hyperalgesia modulated by disease-modifying antirheumatoid drugs in the adjuvant-induced arthritic rat, Arthritis Res Ther, vol.9, issue.5, p.91, 2007. ,
A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis, Arthritis Res Ther, vol.11, issue.6, p.185, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00663553
MTX affects inflammation and tissue destruction differently in the rat AA model, J Rheumatol, vol.28, issue.7, pp.1476-1481, 2001. ,
Combination benefit of a pyrimidylpiperazine derivative (Y-40138) and methotrexate in arthritic rats, Eur J Pharmacol, vol.497, issue.3, pp.351-359, 2004. ,
-hydroxynon-3-yl) Adenine Therapy for Rat Adjuvant Arthritis and the Effect of Methotrexate on In Vivo Purine Metabolism, Eur J Pharm Sci Off J Eur Fed Pharm Sci, vol.31, issue.9, p.206, 2007. ,
Myelosuppressive and hepatotoxic potential of leflunomide and methotrexate combination in a rat model of rheumatoid arthritis, Pharmacol Rep PR, vol.67, issue.1, pp.102-114, 2015. ,
Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat, PLOS ONE, vol.11, issue.5, p.155936, 2016. ,
Pristane-Induced Arthritis in Dark Agouti rat is a relevant model for mimicking vascular dysfunction and lipid paradox in rheumatoid arthritis, Jt Bone Spine Rev Rhum, vol.86, issue.4, pp.483-490, 2019. ,
Independent relationship of osteoprotegerin concentrations with endothelial activation and carotid atherosclerosis in patients with severe rheumatoid arthritis, J Rheumatol, vol.41, issue.3, pp.429-436, 2014. ,
Bone erosion is associated with reduction of circulating endothelial progenitor cells and endothelial dysfunction in rheumatoid arthritis, Arthritis Rheumatol Hoboken NJ, vol.66, issue.6, pp.1450-1460, 2014. ,
BMP signalling in skeletal development, disease and repair, Nat Rev Endocrinol, vol.12, issue.4, pp.203-221, 2016. ,
Peripheral blood expression profiles of bone morphogenetic proteins, tumor necrosis factor-superfamily molecules, and transcription factor Runx2 could be used as markers of the form of arthritis, disease activity, and therapeutic responsiveness, J Rheumatol, vol.37, issue.2, pp.246-256, 2010. ,
Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 ,
, Arthritis Rheum, vol.58, issue.12, pp.3675-3683, 2008.
Methotrexate in atherogenesis and cholesterol metabolism, Cholesterol, p.503028, 2011. ,
A2A Adenosine Receptors Are Differentially Modulated by Pharmacological Treatments in Rheumatoid Arthritis Patients and Their Stimulation Ameliorates Adjuvant-Induced Arthritis in Rats, PLoS ONE, vol.8, issue.1, 2013. ,
Chronic arthritis and cardiovascular disease: altered blood parameters give rise to a prothrombotic propensity, Semin Arthritis Rheum, vol.44, issue.3, pp.345-352, 2014. ,
Homocysteine-Induced Endothelial Dysfunction, Ann Nutr Metab, vol.67, issue.1, pp.1-12, 2015. ,
Creatine supplementation decreased homocysteine plasma levels in rats but not humans: A critical review with meta-analysis, J Nutr Intermed Metab, vol.3, pp.50-57, 2016. ,
Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis, Clin Chim Acta Int J Clin Chem, vol.338, issue.1-2, pp.157-164, 2003. ,
Hyperhomocysteinemia and immune activation, Clin Chem Lab Med, vol.41, issue.11, pp.1438-1443, 2003. ,
Low level of physical activity in women with rheumatoid arthritis is associated with cardiovascular risk factors but not with body fat mass--a cross sectional study, BMC Musculoskelet Disord, vol.12, p.13, 2011. ,
The beneficial effects of Tai Chi exercise on endothelial function and arterial stiffness in elderly women with rheumatoid arthritis, Arthritis Res Ther, vol.17, issue.1, p.380, 2015. ,
Recent advances in arginine metabolism: roles and regulation of the arginases, Br J Pharmacol, vol.157, issue.6, 2009. ,
Effectiveness of arginase inhibitors against experimentally induced stroke, Naunyn Schmiedebergs Arch Pharmacol, vol.391, issue.6, pp.603-612, 2018. ,
Ca A gi ase I hi ito s Be the A s e to The apeutic Challenges i Alzhei e s Disease?, Neurother J Am Soc Exp Neurother, vol.15, issue.4, pp.1032-1035, 2018. ,
Endogenous Nitric Oxide Synthesis Inhibitor Asymmetric Dimethyl l-Arginine Accelerates Endothelial Cell Senescence, Arterioscler Thromb Vasc Biol, vol.24, issue.10, pp.1816-1822, 2004. ,
Long term exposure to L-arginine accelerates endothelial cell senescence through arginase-II and S6K1 signaling, Aging, vol.6, issue.5, pp.369-379, 2014. ,
L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial, JAMA, vol.295, issue.1, pp.58-64, 2006. ,
The role of arginase in aging: A systematic review, Exp Gerontol, vol.116, pp.54-73, 2019. ,
Pharmacokinetics of intravenous and oral L-arginine in normal volunteers, Br J Clin Pharmacol, vol.47, issue.3, pp.261-266, 1999. ,
Anhedonia and motivational deficits in rats: impact of chronic social stress, Behav Brain Res, vol.162, issue.1, pp.127-134, 2005. ,
Feasibility of focal cerebral ischemia and reperfusion surgery combined with chronic unpredictable mild stress to simulate the post-stroke depressive state in rats, Behav Brain Funct BBF, vol.11, p.39, 2015. ,
Efavirenz exposure, alone and in combination with known drugs of abuse, engenders addictive-like bio-behavioural changes in rats, Sci Rep, vol.8, issue.1, p.12837, 2018. ,
Comparative Risk of Cardiovascular Events with Biologic and Synthetic Disease-Modifying Anti-Rheumatic Drugs in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis, Arthritis Care Res, 2019. ,
Potential benefits of biologics on stroke and mortality in patients with rheumatoid arthritis: A nationwide population-based cohort study in Taiwan, Int J Rheum Dis, 2019. ,
Leukoencephalopathy induced by low-dose methotrexate in a patient with rheumatoid arthritis, Intern Med Tokyo Jpn, vol.50, pp.2219-2222, 2011. ,
Leukoencephalopathy due to oral methotrexate, Cerebellum Lond Engl, vol.13, issue.1, pp.178-183, 2014. ,
Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritis, J Cell Mol Med, vol.17, issue.12, pp.1577-1587, 2013. ,
Serum and synovial fluid concentrations of endothelin-1 in patients with rheumatoid arthritis, J Med, vol.30, issue.1-2, pp.51-60, 1999. ,
Elevated plasma endothelin-1 levels and vascular dysregulation in patients with rheumatoid arthritis, Med Sci Monit Int Med J Exp Clin Res, vol.8, issue.9, pp.616-619, 2002. ,
Angiotensin II in inflammation, immunity and rheumatoid arthritis, Clin Exp Immunol, vol.179, issue.2, pp.137-145, 2015. ,
Endothelin-1 levels and cardiovascular events, Trends Cardiovasc Med, 2019. ,
Endothelins modulate inflammatory reaction in zymosan-induced arthritis: participation of LTB4, TNF-alpha, and CXCL-1, J Leukoc Biol, vol.84, issue.3, pp.652-660, 2008. ,
an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-? in the induction of endothelin system genes, Inflamm Res Off J Eur Histamine Res Soc Al, vol.61, issue.4, pp.337-348, 2012. ,
The renin-angiotensin system in the synovium promotes periarticular osteopenia in a rat model of collagen-induced arthritis, Int Immunopharmacol, vol.65, pp.550-558, 2018. ,
Improvement of vascular endothelial function using the oral endothelin receptor antagonist bosentan in patients with systemic sclerosis, Arthritis Rheum, vol.56, issue.6, pp.1985-1993, 2007. ,
Infliximab treatment increases left ventricular ejection fraction in patients with rheumatoid arthritis: assessment of heart function by echocardiography, endothelin 1, interleukin 6, and NT-pro brain natriuretic peptide, J Rheumatol, vol.39, issue.4, pp.701-706, 2012. ,
Differential effects of inhibition of interleukin 1 and 6 on myocardial, coronary and vascular function, Clin Res Cardiol Off J Ger Card Soc, 2019. ,
Rappo t d' valuatio tech ologi ue : Evaluatio de l'i age ie cardiaque non invasive dans le diagnostic des coronaropathies chroniques stables, p.127, 2016. ,
Cardiac endotheliummyocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction, Eur Heart J, vol.36, issue.31, pp.2050-2060, 2015. ,
Cardiac phenotype in mouse models of systemic autoimmunity, Dis Model Mech, vol.12, issue.3, 2019. ,
The extent of ischemia-reperfusion injury in adjuvant arthritis rats, Recent Researches in Environment and Biomedicine, vol.2012, p.6, 2019. ,
zukie icz D. Ischaemic heart preconditioning in rats with adjuvant-induced arthritis, Kardiol Pol, vol.71, issue.8, pp.839-844, 2013. ,
Left Ventricular Regional Dysfunction Using Cardiac Magnetic Resonance Imaging in Rheumatoid Arthritis Patients Without Cardiac Symptoms: Comparison Between Methotrexate and Biologics Treatment Groups, J Rheumatol, vol.41, issue.7, pp.1560-1562, 2014. ,
Low-Dose Methotrexate for the Prevention of Atherosclerotic Events, N Engl J Med, vol.380, issue.8, pp.752-762, 2019. ,
The effect of biological DMARDs on the risk of congestive heart failure in rheumatoid arthritis: a systematic review, Expert Opin Biol Ther, vol.18, issue.5, pp.585-594, 2018. ,
Left ventricular function in rheumatoid arthritis during anti-TNF-? treatment: a speckle tracking prospective echocardiographic study. Monaldi Arch Chest Dis Arch Monaldi Mal Torace, vol.84, p.716, 2016. ,
Relationship between exposure to tumour necrosis factor inhibitor therapy and incidence and severity of myocardial infarction in patients with rheumatoid arthritis, Ann Rheum Dis, vol.76, issue.4, pp.654-660, 2017. ,
Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction, Circulation, vol.117, issue.20, pp.2670-2683, 2008. ,
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study), Am J Cardiol, vol.105, issue.10, pp.1371-1377, 2010. ,
Lowering interleukin-1 activity with anakinra improves myocardial deformation in rheumatoid arthritis, Heart Br Card Soc, vol.95, issue.18, pp.1502-1507, 2009. ,
Increased Inflammatory Activity in Patients 3 Months after Myocardial Infarction with Nonobstructive Coronary Arteries, Clin Chem, 2019. ,
Association of tocilizumab treatment with changes in measures of regional left ventricular function in rheumatoid arthritis, as assessed by cardiac magnetic resonance imaging, Int J Rheum Dis, vol.19, issue.11, pp.1169-1174, 2016. ,