, Gastroenterology, vol.145, pp.1215-1229, 2013.
Non-coding RNAs in human disease, Nat Rev Genet, vol.12, pp.861-874, 2011. ,
MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3, Hepatol Baltim Md, vol.49, p.1595, 2009. ,
Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines, Gastroenterology, vol.130, pp.2113-2129, 2006. ,
Circulating Plasma Levels of ,
, MicroRNA-21 and MicroRNA-221 Are Potential Diagnostic Markers for Primary Intrahepatic Cholangiocarcinoma, PLoS ONE, vol.11, 2016.
Long non-coding RNA in liver diseases, Hepatology, 2014. ,
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma, Cancer Lett, vol.344, pp.20-27, 2014. ,
Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets, J Hepatol, vol.67, pp.603-618, 2017. ,
The functional roles of exosomal long non-coding RNAs in cancer. Cell Mol Life Sci. Epub ahead of print 25, 2019. ,
A ceRNA hypothesis: the Rosetta stone of a hidden RNA language?, Cell, vol.146, pp.353-358, 2011. ,
Circular RNAs in cancer: opportunities and challenges in the field, Oncogene, vol.37, pp.555-565, 2018. ,
BAP1 dependent expression of long noncoding RNA NEAT-1 contributes to sensitivity to gemcitabine in cholangiocarcinoma, Mol Cancer, vol.16, p.22, 2017. ,
Long Noncoding RNA NEAT1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells. Epub ahead of print, 2018. ,
An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles, Mol Cell, vol.33, pp.717-726, 2009. ,
Epigenetic silencing of tumor suppressor gene CDKN1A by oncogenic long non-coding RNA SNHG1 in cholangiocarcinoma, Cell Death Dis ,
, Epub, 2018.
SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2/LSD1/DNMT1 and sponging miR-101-3p in cholangiocarcinoma, J Exp Clin Cancer Res CR, vol.37, 2018. ,
Long non-coding RNA HOTAIR promotes tumorigenesis and forecasts a poor prognosis in cholangiocarcinoma. Sci Rep; 8. Epub ahead of print 15, 2018. ,
Overexpression of long non-coding RNA CRNDE facilitates epithelial-mesenchymal transition and correlates with poor prognosis in intrahepatic cholangiocarcinoma, Oncol Lett, vol.15, pp.4105-4112, 2018. ,
Upregulated long noncoding RNA PANDAR predicts an unfavorable prognosis and promotes tumorigenesis in cholangiocarcinoma, OncoTargets Ther, vol.10, pp.2873-2883, 2017. ,
The prognostic potential and carcinogenesis of long noncoding RNA TUG1 in human cholangiocarcinoma, Oncotarget, vol.8, pp.65823-65835, 2017. ,
LncRNA-CCAT1 Promotes Migration, Invasion, and EMT in Intrahepatic Cholangiocarcinoma Through Suppressing miR-152, Dig Dis Sci, vol.62, pp.3050-3058, 2017. ,
Long non-coding RNA CCAT2 promotes cholangiocarcinoma cells migration and invasion by induction of epithelial-to-mesenchymal transition, Biomed Pharmacother, vol.99, pp.121-127, 2018. ,
Long non-coding RNA UCA1 indicates an unfavorable prognosis and promotes tumorigenesis via regulating AKT/GSK-3 signaling pathway in cholangiocarcinoma, Oncotarget, vol.8, pp.96203-96214, 2017. ,
LncRNA TUG1 sponges miR-145 to promote cancer progression and regulate glutamine metabolism via Sirt3/GDH axis, Oncotarget, vol.8, pp.113650-113661, 2017. ,
Long Non-Coding RNA MALAT1 Interacts With miR-204 to ,
, Modulate Human Hilar Cholangiocarcinoma Proliferation, Migration, and Invasion by Targeting CXCR4, J Cell Biochem
LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner, J Hematol OncolJ Hematol Oncol, vol.9, p.117, 2016. ,
Overexpression of long noncoding RNA H19 indicates a poor prognosis for cholangiocarcinoma and promotes cell migration and invasion by affecting epithelial-mesenchymal transition, Biomed Pharmacother, vol.92, pp.17-23, 2017. ,
A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma, Hepatol Commun, vol.2, pp.254-269, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01744444
Long noncoding RNA PCAT1 regulates extrahepatic cholangiocarcinoma progression via the Wnt/ -catenin-signaling pathway, Biomed Pharmacother, vol.94, pp.55-62, 2017. ,
Enhanced expression of lncRNA TP73-AS1 predicts adverse phenotypes for cholangiocarcinoma and exerts oncogenic properties in vitro and in vivo, Biomed Pharmacother, vol.106, pp.260-266, 2018. ,
Long non-coding RNA MALAT1 promotes cholangiocarcinoma cell proliferation and invasion by activating PI3K/Akt pathway, Neoplasma, vol.64, pp.725-731, 2017. ,
IRF4-induced upregulation of lncRNA SOX2-OT promotes cell proliferation and metastasis in cholangiocarcinoma by regulating SOX2 and PI3K/AKT signaling, Eur Rev Med Pharmacol Sci, vol.22, pp.8169-8178, 2018. ,
Overexpressed long noncoding RNA Sox2ot predicts poor prognosis for cholangiocarcinoma and promotes cell proliferation and invasion, Gene, vol.645, pp.131-136, 2018. ,
Long Noncoding RNA AFAP1-AS1 Promoted Tumor Growth and Invasion in Cholangiocarcinoma, Cell Physiol Biochem, vol.42, pp.222-230, 2017. ,
LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells, Oncotarget, vol.8, pp.58394-58404, 2017. ,
Long non-coding RNA EPIC1 promotes cholangiocarcinoma cell growth, Biochem Biophys Res Commun. Epub, 2018. ,
Long noncoding RNA LINC01296 promotes tumor growth and progression by sponging miR-5095 in human cholangiocarcinoma, Int J Oncol, vol.52, pp.1777-1786, 2018. ,
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer, Nat Genet, vol.48, pp.500-509, 2016. ,
lncRNASNP: a database of SNPs in lncRNAs and their potential functions in human and mouse, Nucleic Acids Res, vol.43, pp.181-186, 2015. ,
A Genetic Variant in Long Non-Coding RNA HULC Contributes to Risk of HBV-Related Hepatocellular Carcinoma in a Chinese Population, PLoS ONE, vol.7, p.35145, 2012. ,
Identification of microRNAs as biomarkers for cholangiocarcinoma detection: A diagnostic meta-analysis, Clin Res Hepatol Gastroenterol, vol.41, pp.156-162, 2017. ,
Serum miR-26a as a diagnostic and prognostic biomarker in cholangiocarcinoma, Oncotarget, vol.6, pp.18631-18640, 2015. ,
miRNA and lncRNA as biomarkers in cholangiocarcinoma(CCA), Oncotarget, vol.8, pp.100819-100830, 2017. ,
Upregulation of gastric adenocarcinoma predictive long intergenic non-coding RNA promotes progression and predicts poor prognosis in perihilar cholangiocarcinoma, Oncol Lett, vol.16, pp.3964-3972, 2018. ,
LncRNA CCAT1 as the unfavorable prognostic biomarker for cholangiocarcinoma, Eur Rev Med Pharmacol Sci, vol.21, pp.1242-1247, 2017. ,
Upregulated long noncoding RNA PANDAR predicts an unfavorable prognosis and promotes tumorigenesis in cholangiocarcinoma. OncoTargets and Therapy. Epub ahead of print 6, 2017. ,
Co-expression of the carbamoyl-phosphate synthase 1 gene and its long non-coding RNA correlates with poor prognosis of patients with intrahepatic cholangiocarcinoma, Mol Med Rep, vol.12, pp.7915-7926, 2015. ,
Long noncoding RNAs as novel serum biomarkers for the diagnosis of hepatocellular carcinoma: a systematic review and meta-analysis, Clin Transl Oncol, vol.19, pp.961-968, 2017. ,
The Plasma LncRNA Acting as Fingerprint in Hilar Cholangiocarcinoma, Cell Physiol Biochem, vol.49, pp.1694-1702, 2018. ,
An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells, Oncotarget, vol.7, pp.73257-73269, 2016. ,
PredcircRNA: computational classification of circular RNA from other long non-coding RNA using hybrid features, Mol Biosyst, vol.11, pp.2219-2226, 2015. ,
Regulation of circRNA biogenesis, RNA Biol, vol.12, pp.381-388, 2015. ,
A novel prognostic biomarker for cholangiocarcinoma: circRNA Cdr1as, Eur Rev Med Pharmacol Sci, vol.22, pp.365-371, 2018. ,
Downregulated circular RNA hsa_circ_0001649 regulates proliferation, migration and invasion in cholangiocarcinoma cells, Biochem Biophys Res Commun, vol.496, pp.455-461, 2018. ,
Network analyses-based identification of circular ribonucleic acid-related pathways in intrahepatic cholangiocarcinoma: Tumor Biol. Epub ahead of print 31, vol.87, 2018. ,
, ème congrès annuel de l'International Liver Cancer Association (ILCA) en
Is systematic nasogastric decompression after pancreaticoduodenectomy really necessary?, Langenbecks Arch Surg, vol.403, issue.5, pp.573-580, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01833941
,
, Pancreatico-jejunostomy decreases post-operative pancreatic fistula incidence and severity after central pancreatectomy, ANZ J Surg, vol.88, issue.1-2, pp.77-81, 2018.
Venous stent in liver transplant candidates: dodging the top tip traps, Liver Transplantation, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01558817
,
Preoperative bevacizumab and surgery for colorectal liver metastases: a propensity score analysis, Langenbecks Arch Surg, vol.402, pp.57-67, 2017. ,
,
Frey procedure combined with biliary diversion in chronic pancreatitis, Surgery, vol.160, pp.1264-70, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01414694
,
, Hepatic artery reinforcement after post pancreatectomy haemorrhage caused by pancreatitis, Gland Surg, vol.5, pp.427-457, 2016.
A weird polyp, 8 years after the Whipple procedure, Surgery, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01560559
Impact of stroma LOXL2 overexpression on the prognosis of intrahepatic cholangiocarcinoma, J Surg Res, vol.203, pp.441-50, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-01341595
An unusual case of adrenocortical carcinoma with liver metastasis that occurred at 23 years after surgery, Hepatobiliary Surg Nutr, vol.5, pp.265-273, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01334069
,
, An Unusual Intussusception. J Pediatr, vol.175, p.240, 2016.
,
, J Surg Oncol, vol.113, pp.575-80, 2016.
,
Extended liver resections for intrahepatic cholangiocarcinoma: friend or foe?, Surgery, vol.157, pp.656-65, 2015. ,
Predictors of long-term survival following resection for ampullary carcinoma: a large retrospective French multicentric study, Pancreas, vol.43, pp.692-699, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01971505
,
, Hepatobiliary Pancreat Dis Int, 2014.
Pathology and Genetics of Tumours of the Digestive System, Report-Series/Who-Iarc-Classification-Of-Tumours/Pathology-And-Genetics-Of-Tumours-Of-The-Digestive, 2000. ,
Clinical diagnosis and staging of cholangiocarcinoma, Nat Rev Gastroenterol Hepatol, vol.8, pp.512-522, 2011. ,
, The Epidemiology of Cholangiocarcinoma. Semin Liver Dis, vol.24, pp.115-125, 2004.
Epidemiology and risk factors, Transl Gastrointest Cancer, vol.1, pp.21-32, 2011. ,
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA), Nat Rev Gastroenterol Hepatol, vol.13, pp.261-280, 2016. ,
Multicentre study of the impact of morbidity on long-term survival following hepatectomy for intrahepatic cholangiocarcinoma, BJS, vol.103, pp.1887-1894, 2016. ,
Classification, Diagnosis, and Management of Cholangiocarcinoma, Clin Gastroenterol Hepatol, vol.11, pp.13-21, 2013. ,
Are common factors involved in the pathogenesis of primary liver cancers? A meta-analysis of risk factors for intrahepatic cholangiocarcinoma, J Hepatol, vol.57, pp.69-76, 2012. ,
Rising incidence of intrahepatic cholangiocarcinoma in the United States: a true increase?, J Hepatol, vol.40, pp.472-477, 2004. ,
Rising trends in cholangiocarcinoma: Is the ICD classification system misleading us, J Hepatol, vol.56, pp.848-854, 2012. ,
Metabolic syndrome increases the risk of primary liver cancer in the United States: a population-based case-control study, Hepatol Baltim Md, vol.54, pp.463-471, 2011. ,
Intrahepatic cholangiocarcinoma: macroscopic type and stage classification, J Hepatobiliary Pancreat Surg, vol.10, pp.288-291, 2003. ,
Treatment and prognosis for patients with intrahepatic cholangiocarcinoma: Systematic review and meta-analysis, JAMA Surg, vol.149, pp.565-574, 2014. ,
The expression of cytokeratins 7, 19, and 20 in primary and metastatic carcinomas of the liver, Mod Pathol Off J U S Can Acad Pathol Inc, vol.9, pp.901-909, 1996. ,
Cytokeratin 7 and 20 Expression in Cholangiocarcinomas Varies Along the Biliary Tract But Still Differs From That in Colorectal Carcinoma Metastasis, Am J Surg Pathol, vol.24, pp.870-876, 2000. ,
Desmoplastic Stroma and Cholangiocarcinoma: Clinical Implications and Therapeutic Targeting, Hepatol Baltim Md, vol.59, pp.2397-2402, 2014. ,
The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma, Nat Rev Gastroenterol Hepatol, vol.9, pp.44-54, 2012. ,
Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma, Hepatol Baltim Md, vol.58, 1992. ,
URL : https://hal.archives-ouvertes.fr/hal-01068717
Transforming Growth Factor--Induced Cell Plasticity in Liver Fibrosis and Hepatocarcinogenesis. Front Oncol; 8. Epub ahead of print 10, 2018. ,
Profiles of Cancer Stem Cell Subpopulations in Cholangiocarcinomas, Am J Pathol, vol.185, pp.1724-1739, 2015. ,
Cholangiocarcinomas can originate from hepatocytes in mice, J Clin Invest, vol.122, pp.2911-2915, 2012. ,
Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes, J Clin Invest, vol.122, pp.3914-3918, 2012. ,
Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma, Am Assoc Cancer Res, vol.22, pp.291-300, 2016. ,
Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors, Gastroenterology, vol.142, pp.1021-1031, 2012. ,
Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma, Hepatology, vol.59, pp.1427-1434, 2014. ,
Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies, Oncogene, vol.32, pp.4861-4870, 2013. ,
Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes, Gastroenterology, vol.144, pp.829-840, 2013. ,
The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis, Am J Gastroenterol, vol.95, pp.204-207, 2000. ,
Influence of Hepatic Resection Margin on Recurrence and Survival in Intrahepatic Cholangiocarcinoma, Ann Surg Oncol, vol.15, pp.2787-2794, 2008. ,
Serum Cytokeratin 19 Fragment (CYFRA21-1) as a Prognostic Factor in Intrahepatic Cholangiocarcinoma, Ann Surg Oncol, vol.15, pp.583-589, 2008. ,
Elevated levels of circulating osteopontin are associated with a poor survival after resection of cholangiocarcinoma, J Hepatol, vol.67, pp.749-757, 2017. ,
Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma, J Surg Res ,
URL : https://hal.archives-ouvertes.fr/hal-01069630
Impact of stroma LOXL2 overexpression on the prognosis of intrahepatic cholangiocarcinoma, J Surg Res, vol.203, pp.441-450, 2016. ,
URL : https://hal.archives-ouvertes.fr/inserm-01341595
Serum extracellular vesicles contain protein biomarkers for primary sclerosing cholangitis and cholangiocarcinoma, Hepatology, vol.66, pp.1125-1143, 2017. ,
Intrahepatic peripheral cholangiocarcinoma: CT evaluation, Abdom Imaging, vol.25, pp.490-496, 2000. ,
Treatment of recurrent intrahepatic cholangiocarcinoma, Br J Surg, vol.99, pp.1711-1717, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-00865290
Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma, J Hepatol, vol.60, pp.1268-1289, 2014. ,
Current status of liver transplantation for cholangiocarcinoma, Liver Transpl, vol.24, pp.294-303, 2018. ,
Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer, N Engl J Med, vol.362, pp.1273-1281, 2010. ,
Adjuvant Therapy for Resected Biliary Tract Cancer: ASCO Clinical Practice Guideline, J Clin Oncol, 2019. ,
Gemcitabine and Oxaliplatin Chemotherapy or Surveillance in Resected Biliary Tract Cancer (PRODIGE 12-ACCORD 18-UNICANCER GI): A Randomized Phase III Study, J Clin Oncol, vol.37, pp.658-667, 2019. ,
Glass Microspheres 90Y Selective Internal Radiation Therapy and Chemotherapy as First-Line Treatment of Intrahepatic Cholangiocarcinoma, Clin Nucl Med, vol.40, pp.851-855, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01187323
Systemic and Adjuvant Therapies for Intrahepatic Cholangiocarcinoma, Cancer Control J Moffitt Cancer Cent, vol.24, 2017. ,
Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances. Hepatology; 0 ,
Combined Nivolumab and Ipilimumab or Monotherapy in Previously Untreated Melanoma, N Engl J Med, vol.373, pp.23-34, 2015. ,
TGF signalling in context, Nat Rev Mol Cell Biol, vol.13, pp.616-630, 2012. ,
The logic of TGF signaling, FEBS Lett, vol.580, pp.2811-2820, 2006. ,
Targeting the TGF signalling pathway in disease, Nat Rev Drug Discov, vol.11, pp.790-811, 2012. ,
TGF-: Duality of Function Between Tumor Prevention and Carcinogenesis, JNCI J Natl Cancer Inst, vol.106, 2014. ,
SMAD7: a timer of tumor progression targeting TGF-signaling, Tumor Biol, pp.1-7, 2014. ,
, Massagué J. TGF in Cancer. Cell, vol.134, pp.215-230, 2008.
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front, Histochem Cell Biol, vol.130, pp.481-494, 2008. ,
Epithelial-mesenchymal transition in cholangiocarcinoma: From clinical evidence to regulatory networks, J Hepatol, vol.66, pp.424-441, 2017. ,
URL : https://hal.archives-ouvertes.fr/hal-01377000
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer, Nat Rev Mol Cell Biol, vol.20, p.69, 2019. ,
Epigenetic Regulation of Cancer Stem Cell Marker CD133 by Transforming Growth Factor, Hepatol Baltim Md, vol.51, pp.1635-1644, 2010. ,
CD133+ Liver Cancer Stem Cells from Methionine Adenosyl Transferase 1A-Deficient Mice Demonstrate Resistance to Transforming Growth Factor (TGF)--Induced Apoptosis, Hepatol Baltim Md, vol.49, pp.1277-1286, 2009. ,
TGF-1 expression and angiogenesis in colorectal cancer tissue, World J Gastroenterol, vol.8, pp.496-498, 2002. ,
Controlling the Angiogenic Switch: A Balance between Two Distinct TGF-b Receptor Signaling Pathways, Trends Cardiovasc Med, vol.13, pp.301-307, 2003. ,
TGF primes breast tumors for lung metastasis seeding through angiopoietin-like 4, Cell, vol.133, pp.66-77, 2008. ,
Overactivation of the TGF-pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells, Hepatology, vol.58, pp.2032-2044, 2013. ,
Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-1/Snail Activation Aggravates Invasive Growth of Cholangiocarcinoma, Am J Pathol, vol.177, pp.141-152, 2010. ,
Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma, Hepatology, vol.56, pp.1792-1803, 2012. ,
Transforming Growth Factors ? and Are Essential for Modeling Cholangiocarcinoma Desmoplasia and Progression in a Three-Dimensional Organotypic Culture Model, Am J Pathol, vol.187, pp.1068-1092, 2017. ,
Effect of transforming growth factor-1 on human intrahepatic cholangiocarcinoma cell growth, World J Gastroenterol WJG, vol.12, pp.6316-6324, 2006. ,
Expression of transforming growth factor 1 promotes cholangiocarcinoma development and progression, Cancer Lett, vol.380, pp.153-162, 2016. ,
Intrahepatic cholangiocarcinoma escapes from growth inhibitory effect of transforming growth factor-1 by overexpression of cyclin D1, Lab Invest, vol.85, pp.572-581, 2005. ,
Transforming Growth Factor 1 Stimulates Vascular Endothelial Growth Factor Gene Transcription in Human Cholangiocellular Carcinoma Cells, Cancer Res, vol.63, pp.1083-1092, 2003. ,
TGF-1 expression is associated with invasion and metastasis of intrahepatic cholangiocarcinoma, Biol Res, vol.48, 2015. ,
Mutational landscape of intrahepatic cholangiocarcinoma, Nat Commun, vol.5, p.5696, 2014. ,
Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations, Oncotarget, vol.7, pp.23825-23836, 2016. ,
Epithelial Transforming Growth Factor-Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma, Gastroenterology ,
The Landscape of Long Noncoding RNAs in the Human Transcriptome, Nat Genet, vol.47, pp.199-208, 2015. ,
Circular RNAs are a large class of animal RNAs with regulatory potency, Nature, vol.495, pp.333-338, 2013. ,
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression, Genome Res, vol.22, pp.1775-1789, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-01205054
Non-coding RNAs in hepatocellular carcinoma: molecular functions and pathological implications, Nat Rev Gastroenterol Hepatol, vol.15, pp.137-151, 2018. ,
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma, Cancer Lett, vol.344, pp.20-27, 2014. ,
Long noncoding RNAs: Cellular address codes in development and disease, Cell, vol.152, pp.1298-1307, 2013. ,
Long noncoding RNA programs active chromatin domain to coordinate homeotic gene activation, Nature, vol.472, pp.120-124, 2011. ,
Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes, Science, vol.329, pp.689-693, 2010. ,
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters, Nat Genet, vol.43, pp.621-629, 2011. ,
The long reach of noncoding RNAs, Nat Genet, vol.43, pp.616-617, 2011. ,
The H19 non-coding RNA is essential for human tumor growth, PloS One, vol.2, p.845, 2007. ,
The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r, Nat Cell Biol, vol.14, pp.659-665, 2012. ,
PTENp1, a natural sponge of miR-21, mediates PTEN expression to inhibit the proliferation of oral squamous cell carcinoma, Mol Carcinog, vol.56, pp.1322-1334, 2017. ,
, NcRNAs and Cholangiocarcinoma. J Cancer, vol.9, pp.100-107, 2018.
Coding-noncoding gene expression in intrahepatic cholangiocarcinoma, Transl Res, vol.168, pp.107-121, 2016. ,
Comprehensive analysis of long noncoding RNA-associated competing endogenous RNA network in cholangiocarcinoma, Biochem Biophys Res Commun, vol.506, pp.1004-1012, 2018. ,
Comprehensive analysis of aberrantly expressed profiles of lncRNAs, miRNAs and mRNAs with associated ceRNA network in cholangiocarcinoma, Cancer Biomark, vol.23, pp.549-559, 2018. ,
Genome-wide analysis of long noncoding RNA and mRNA co-expression profile in intrahepatic cholangiocarcinoma tissue by RNA sequencing, Oncotarget, vol.8, pp.26591-26599, 2017. ,
Epigenetic silencing of tumor suppressor gene CDKN1A by oncogenic long non-coding RNA SNHG1 in cholangiocarcinoma, Cell Death Dis, vol.9, 2018. ,
Long Noncoding RNA NEAT1 Promotes Growth and Metastasis of Cholangiocarcinoma Cells, Oncol Res, vol.26, pp.879-888, 2018. ,
Long non-coding RNA EPIC1 promotes cholangiocarcinoma cell growth, Biochem Biophys Res Commun. Epub, 2018. ,
Long non-coding RNA MALAT1 promotes cholangiocarcinoma cell proliferation and invasion by activating PI3K/Akt pathway, Neoplasma, vol.64, pp.725-731, 2017. ,
Overexpression of long non-coding RNA CRNDE facilitates epithelial-mesenchymal transition and correlates with poor prognosis in intrahepatic cholangiocarcinoma, Oncol Lett, vol.15, pp.4105-4112, 2018. ,
LncRNA TUG1 sponges miR-145 to promote cancer progression and regulate glutamine metabolism via Sirt3/GDH axis, Oncotarget, vol.8, pp.113650-113661, 2017. ,
The prognostic potential and carcinogenesis of long noncoding RNA TUG1 in human cholangiocarcinoma, Oncotarget, vol.8, pp.65823-65835, 2017. ,
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition, Genes Dev, vol.22, pp.756-769, 2008. ,
A Long Noncoding RNA Activated by TGF-Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma, Cancer Cell, vol.25, pp.666-681, 2014. ,
Long noncoding RNA activated by TGF-in human cancers: A meta-analysis, Clin Chim Acta, vol.468, pp.10-16, 2017. ,
A Transforming Growth Factor-and H19 ,
, Signaling Axis in Tumor-Initiating Hepatocytes That Regulates Hepatic Carcinogenesis. Hepatology; 0. Epub ahead of print 16, 2018.
Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer, FEBS Open Bio, vol.4, pp.458-467, 2014. ,
MEG3 long noncoding RNA regulates the TGFpathway genes through formation of RNA-DNA triplex structures, Nat, 2015. ,
Inhibitory effects of long noncoding RNA MEG3 on hepatic stellate cells activation and liver fibrogenesis, Biochim Biophys Acta, vol.1842, pp.2204-2215, 2014. ,
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer, Oncogene, vol.30, pp.4750-4756, 2011. ,
A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma, Cell Death Dis, vol.5, p.1549, 2014. ,
Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers, Br J Cancer, vol.110, pp.164-171, 2014. ,
Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2, Hepatology, vol.60, pp.1278-1290, 2014. ,
Long non-coding RNA ANRIL promotes the invasion and metastasis of thyroid cancer cells through TGF-/Smad signaling pathway, Oncotarget, vol.7, pp.57903-57918, 2016. ,
ANRIL inhibits p15INK4b through the TGF 1 signaling pathway in human esophageal squamous cell carcinoma, Cell Immunol, vol.289, pp.91-96, 2014. ,
ANRIL: Molecular Mechanisms and Implications in Human Health, Int J Mol Sci, vol.14, pp.1278-1292, 2013. ,
Knockdown of LncRNA ANRIL suppresses cell proliferation, metastasis, and invasion via regulating miR-122-5p expression in hepatocellular carcinoma, J Cancer Res Clin Oncol, vol.144, pp.205-214, 2018. ,
The human keratins: biology and pathology, Histochem Cell Biol, vol.129, pp.705-733, 2008. ,
Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients, PLoS ONE, vol.12, 2017. ,
Keratin 17 is overexpressed and predicts poor survival in estrogen receptor-negative/human epidermal growth factor receptor-2-negative breast cancer, Hum Pathol, vol.62, pp.23-32, 2017. ,
Keratin 17 Expression Correlates with Tumor Progression and Poor Prognosis in Gastric Adenocarcinoma, Ann Surg Oncol, vol.19, pp.3506-3514, 2012. ,
Immunohistochemical staining in the diagnosis of pancreatobiliary and ampulla of Vater adenocarcinoma: application of CDX2, CK17, MUC1, and MUC2, Am J Surg Pathol, vol.29, pp.359-367, 2005. ,
The long noncoding RNA LINC00312 induces lung adenocarcinoma migration and vasculogenic mimicry through directly binding YBX1. Mol Cancer; 17. Epub ahead of print 23, 2018. ,
Overexpression of long intergenic noncoding RNA LINC00312 inhibits the invasion and migration of thyroid cancer cells by downregulating microRNA-197-3p, Biosci Rep, vol.37, 2017. ,
LINC00312 inhibits the migration and invasion of bladder cancer cells by targeting miR-197-3p, Tumor Biol, vol.37, pp.14553-14563, 2016. ,
Differentially expressed protein-coding genes and long noncoding RNA in early-stage lung cancer, Tumor Biol, vol.36, pp.9969-9978, 2015. ,
Long noncoding RNA LINC00313 modulates papillary thyroid cancer tumorigenesis via sponging miR-4429, Neoplasma, vol.65, pp.933-942, 2018. ,
The CASC15 long intergenic non-coding RNA locus is involved in melanoma progression and phenotype-switching, J Invest Dermatol, vol.135, pp.2464-2474, 2015. ,
Long non-coding RNA CASC15 promotes melanoma progression by epigenetically regulating PDCD4. Cell Biosci; 8. Epub ahead of print 13, 2018. ,
CASC15-S is a tumor suppressor lncRNA at the 6p22 neuroblastoma susceptibility locus, Cancer Res, vol.75, pp.3155-3166, 2015. ,
Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis, Cancer Cell, vol.33, pp.417-434, 2018. ,
CASC15 gene polymorphisms reduce neuroblastoma risk in Chinese children, Oncotarget, vol.8, pp.91343-91349, 2017. ,
An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles, Mol Cell, vol.33, pp.717-726, 2009. ,
Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli, Mol Cell, vol.53, pp.393-406, 2014. ,
The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites, Mol Cell, vol.55, pp.791-802, 2014. ,
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer, Nat Genet, vol.48, pp.500-509, 2016. ,
SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2/LSD1/DNMT1 and sponging miR-101-3p in cholangiocarcinoma, J Exp Clin Cancer Res CR, vol.37, 2018. ,
Long non-coding RNA CASC15 regulates gastric cancer cell proliferation, migration and epithelial mesenchymal transition by targeting CDKN1A and ZEB1, Mol Oncol, vol.12, pp.799-813, 2018. ,
Long non-coding RNA CASC15 is upregulated in hepatocellular carcinoma and facilitates hepatocarcinogenesis, Int J Oncol, vol.51, pp.1722-1730, 2017. ,
LncRNA CASC15 promotes colon cancer cell proliferation and metastasis by regulating the miR-4310/LGR5/Wnt/ -catenin signaling pathway, Mol Med Rep, vol.18, pp.2269-2276, 2018. ,
miRNA and lncRNA as biomarkers in cholangiocarcinoma(CCA), Oncotarget, vol.8, pp.100819-100830, 2017. ,
Human bile contains MicroRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis, Hepatology, vol.60, pp.896-907, 2014. ,
The Plasma LncRNA Acting as Fingerprint in Hilar Cholangiocarcinoma, Cell Physiol Biochem, vol.49, pp.1694-1702, 2018. ,
The diagnostic/prognostic potential and molecular functions of long non-coding RNAs in the exosomes derived from the bile of human cholangiocarcinoma, Oncotarget, vol.8, pp.69995-70005, 2017. ,
Circular RNAs: A novel type of biomarker and genetic tools in cancer. Oncotarget; 8. Epub ahead of print 8, 2017. ,
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk, PLoS Genet, vol.6, issue.2, 2010. ,
Downregulated circular RNA hsa_circ_0001649 regulates proliferation, migration and invasion in cholangiocarcinoma cells, Biochem Biophys Res Commun, vol.496, pp.455-461, 2018. ,
A novel prognostic biomarker for cholangiocarcinoma: circRNA Cdr1as, Eur Rev Med Pharmacol Sci, vol.22, pp.365-371, 2018. ,
Cell-Type Specific Features of Circular RNA Expression, PLoS Genet, vol.9, p.1003777, 2013. ,
Long-noncoding RNAs in basal cell carcinoma, Tumor Biol, vol.37, pp.10595-10608, 2016. ,
TGF-signaling pathway as a pharmacological target in liver diseases, Pharmacol Res, vol.85, pp.15-22, 2014. ,
Effects of TGF-signalling inhibition with galunisertib (LY2157299) in hepatocellular carcinoma models and in ex vivo whole tumor tissue samples from patients, Oncotarget, vol.6, pp.21614-21627, 2015. ,
TGF-signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures, PLoS ONE, vol.12, 2017. ,
Role of crosstalk between interleukin-6 and transforming growth factor-1 in epithelial-mesenchymal transition and chemoresistance in biliary tract cancer, Eur J Cancer, vol.49, pp.1725-1740, 2013. ,
Transforming growth factor-1-induced epithelialmesenchymal transition generates ALDH-positive cells with stem cell properties in cholangiocarcinoma, Cancer Lett, vol.354, pp.320-328, 2014. ,
Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model, Hepatology, vol.65, pp.501-514, 2017. ,
LncRNA CACS15 contributes to oxaliplatin resistance in colorectal cancer by positively regulating ABCC1 through sponging miR-145, Arch Biochem Biophys, vol.663, pp.183-191, 2019. ,
An artificial lncRNA targeting multiple miRNAs overcomes sorafenib resistance in hepatocellular carcinoma cells, Oncotarget, vol.7, pp.73257-73269, 2016. ,