J. Acquavella, G. Olsen, P. Cole, B. Ireland, J. Kaneene et al., Cancer among farmers: a meta-analysis, Annals of epidemiology, vol.8, issue.1, pp.64-74, 1998.

T. Akerstedt, J. Narusyte, P. Svedberg, G. Kecklund, and K. Alexanderson, Night work and prostate cancer in men: a Swedish prospective cohort study, BMJ Open, vol.7, issue.6, p.15751, 2017.

M. Alvarez-cubero, C. Entrala, F. Fernandez-rosado, L. Martinez-gonzalez, J. Alvarez et al., Predictive value in the analysis of RNASEL genotypes in relation to prostate cancer, Prostate cancer and prostatic diseases, vol.15, issue.2, p.144, 2012.

M. J. Alvarez-cubero, L. J. Martinez-gonzalez, M. Saiz, P. Carmona-saez, J. C. Alvarez et al., Prognostic role of genetic biomarkers in clinical progression of prostate cancer, Experimental & molecular medicine, vol.47, issue.8, p.176, 2015.

C. I. Amos, J. Dennis, Z. Wang, J. Byun, F. R. Schumacher et al.,

A. Haiman, C. Kamal, D. Luccarini, D. Tessier, F. Vincent et al.,

P. Kuchenbaecker, J. Soucy, J. M. Manz, K. Cunningham, Z. Butterbach et al.,

S. Fitzgerald, M. Lindstrom, J. D. Adams, C. M. Mckay, S. Phelan et al.,

M. Brennan, T. A. Riggan, H. O'mara, Y. Shen, D. J. Shi et al.,

A. Nielsen, S. Berchuck, S. L. Laboissiere, T. Schmit, C. K. Shelford et al.,

S. K. Field, K. Park, M. Offit, R. Thomassen, L. Schmutzler et al.,

U. Amin-al-olama, R. A. Peters, M. F. Eeles, E. Seldin, D. Gillanders et al., The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers, Cancer Epidemiol Biomarkers Prev, vol.26, issue.1, pp.126-135, 2017.

G. L. Andriole, E. D. Crawford, R. L. Grubb, I. , S. S. Buys et al., , 2012.

. Prostate, C. Lung, and O. , Cancer Screening Trial: mortality results after 13 years of follow-up, Journal of the National Cancer Institute, vol.104, issue.2, pp.125-132

V. N. Anisimov, Light pollution, reproductive function and cancer risk, Neuro Endocrinol Lett, vol.27, issue.1-2, pp.35-52, 2006.

S. N. Archer, D. L. Robilliard, D. J. Skene, M. Smits, A. Williams et al., A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference, Sleep, vol.26, issue.4, pp.413-415, 2003.

S. N. Archer, C. Schmidt, G. Vandewalle, and D. J. Dijk, Phenotyping of PER3 variants reveals widespread effects on circadian preference, sleep regulation, and health, Sleep Med Rev, vol.40, pp.109-126, 2018.

J. Arendt, Shift work: coping with the biological clock, Occupational medicine, vol.60, issue.1, pp.10-20, 2010.

K. J. Aronson, J. Siemiatycki, R. Dewar, and M. Gerin, Occupational risk factors for prostate cancer: results from a case-control study in Montreal, Am J Epidemiol, vol.143, issue.4, pp.363-373, 1996.

I. E. Ashkenazi, A. E. Reinberg, and Y. Motohashi, Interindividual differences in the flexibility of human temporal organization: pertinence to jet lag and shiftwork, Chronobiology international, vol.14, issue.2, pp.99-113, 1997.

V. Bagnardi, M. Rota, E. Botteri, I. Tramacere, F. Islami et al., Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis, British journal of cancer, vol.112, issue.3, p.580, 2015.

P. R. Band, N. D. Le, R. Fang, M. Deschamps, A. J. Coldman et al., , 1996.

, Cohort study of Air Canada pilots: mortality, cancer incidence, and leukemia risk, American Journal of Epidemiology, vol.143, issue.2, pp.137-143

P. R. Band, J. J. Spinelli, V. Ng, J. Moody, and R. P. Gallagher, Mortality and cancer incidence in a cohort of commercial airline pilots, Aviation, space, and environmental medicine, vol.61, issue.4, pp.299-302, 1990.

T. Behrens, K. S.-rabstein, R. Wichert, L. Erbel, M. Eisele et al., Shift work and the incidence of prostate cancer: a 10-year follow-up of a German population-based cohort study, Scandinavian journal of work, vol.43, issue.6, pp.560-568, 2017.

T. Behrens, K. S.-rabstein, R. Wichert, L. Erbel, M. Eisele et al.,

H. , Shift work and the incidence of prostate cancer: a 10-year follow-up of a German population-based cohort study, Scand J Work Environ Health, 2017.

S. Benafif, Z. Kote-jarai, and R. A. Eeles, A Review of Prostate Cancer Genome-Wide Association Studies (GWAS), Cancer Epidemiol Biomarkers Prev, vol.27, issue.8, pp.845-857, 2018.

Y. Benjamini and Y. Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the royal statistical society. Series B (Methodological, pp.289-300, 1995.

I. Benke, M. Leitzmann, G. Behrens, and D. Schmid, Physical activity in relation to risk of prostate cancer: a systematic review and meta-analysis, Annals of Oncology, vol.29, issue.5, pp.1154-1179, 2018.

C. Benna, C. Helfrich-forster, S. Rajendran, H. Monticelli, P. Pilati et al., Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis, Oncotarget, vol.8, issue.14, pp.23978-23995, 2017.

A. Bergstrom, P. Pisani, V. Tenet, A. Wolk, and H. O. Adami, Overweight as an avoidable cause of cancer in Europe, Int J Cancer, vol.91, issue.3, pp.421-430, 2001.

J. Beuten, J. A. Gelfond, J. L. Franke, S. Shook, T. L. Johnson-pais et al., Single and multivariate associations of MSR1, ELAC2, and RNASEL with prostate cancer in an ethnic diverse cohort of men, Cancer Epidemiol Biomarkers Prev, vol.19, issue.2, pp.588-599, 2010.

F. Binder-foucard, A. Belot, P. Delafosse, L. Remontet, A. Woronoff et al., , 2013.

, Estimation nationale de l'incidence et de la mortalité par cancer en France entre, 1980.

A. Blair, S. H. Zahm, N. E. Pearce, E. F. Heineman, and J. F. Fraumeni, Clues to cancer etiology from studies of farmers, Scandinavian journal of work, pp.209-215, 1992.

P. Bosset, A. De-la-taille, and M. Roupret, Enseignement d'Urologie Polycopié. Collège Français des Urologues, pp.86-104, 2014.

D. G. Bostwick, H. B. Burke, D. Djakiew, S. Euling, S. M. Ho et al., Human prostate cancer risk factors, Cancer: Interdisciplinary International Journal of the American Cancer Society, vol.101, issue.S10, pp.2371-2490, 2004.

O. W. Brawley, Prostate cancer epidemiology in the United States, World journal of urology, vol.30, issue.2, pp.195-200, 2012.

C. Broc, M. Evangelou, P. Guenel, T. Truong, and B. Liquet, Investigating Gene-and Pathway-environment Interaction analysis approaches, Journal de la Société Française de Statistique, vol.159, issue.2, pp.56-83, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02136012

S. A. Brown and A. Azzi, Peripheral circadian oscillators in mammals, Circadian clocks, pp.45-66, 2013.

A. Buja, J. H. Lange, E. Perissinotto, G. Rausa, F. Grigoletto et al., Cancer incidence among male military and civil pilots and flight attendants: an analysis on published data, Toxicology and Industrial Health, vol.21, issue.9, pp.273-282, 2005.

Q. Cao, S. Gery, A. Dashti, D. Yin, Y. Zhou et al., A role for the clock gene per1 in prostate cancer, Cancer Res, vol.69, pp.7619-7625, 2009.

B. S. Carter, T. H. Beaty, G. D. Steinberg, B. Childs, and P. C. Walsh, Mendelian inheritance of familial prostate cancer, Proceedings of the National Academy of Sciences, vol.89, issue.8, pp.3367-3371, 1992.

N. Cermakian and D. Boivin, The regulation of central and peripheral circadian clocks in humans, Obesity Reviews, vol.10, issue.s2, pp.25-36, 2009.

J. M. Chan and E. L. Giovannucci, Dairy products, calcium, and vitamin D and risk of prostate cancer, Epidemiologic reviews, vol.23, issue.1, pp.87-92, 2001.

S. T. Chen, K. B. Choo, M. F. Hou, K. T. Yeh, S. J. Kuo et al., Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers, Carcinogenesis, vol.26, issue.7, pp.1241-1246, 2005.

X. Chen, Y. Wang, W. Zang, Y. Du, M. Li et al., miR-194 targets RBX1 gene to modulate proliferation and migration of gastric cancer cells, Tumour Biol, vol.36, issue.4, pp.2393-2401, 2015.

L. Chu, Y. Zhu, K. Yu, T. Zheng, H. Yu et al., Variants in circadian genes and prostate cancer risk: a population-based study in China, Prostate cancer and prostatic diseases, vol.11, issue.4, pp.342-348, 2008.

L. W. Chu, C. Till, B. Yang, C. M. Tangen, P. J. Goodman et al.,

I. Ambrosone, R. Thompson, A. W. Leach, and . Hsing, Circadian genes and risk of prostate cancer in the prostate cancer prevention trial, Mol Carcinog, vol.57, issue.3, pp.462-466, 2018.

L. W. Chu, Y. Zhu, K. Yu, T. Zheng, H. Yu et al.,

M. C. Danforth, F. Z. Shen, Y. T. Stanczyk, A. W. Gao, and . Hsing, Variants in circadian genes and prostate cancer risk: a population-based study in China, Prostate Cancer Prostatic Dis, vol.11, issue.4, pp.342-348, 2008.

B. Claustrat, Mélatonine et troubles du rythme veille-sommeil, Médecine du Sommeil, vol.6, issue.1, pp.12-24, 2009.

M. Cohen, M. Lippman, and B. Chabner, Pineal gland and breast cancer, The Lancet, vol.312, issue.8104, pp.1381-1382, 1978.

P. Cole, D. Trichopoulos, H. Pastides, T. Starr, and J. S. Mandel, Dioxin and cancer: a critical review, Regulatory Toxicology and Pharmacology, vol.38, issue.3, pp.378-388, 2003.

M. Conlon, N. Lightfoot, and N. Kreiger, Rotating shift work and risk of prostate cancer, Epidemiology, vol.18, issue.1, pp.182-183, 2007.

K. A. Cooney, Inherited Predisposition to Prostate Cancer: From Gene Discovery to Clinical Impact, Trans Am Clin Climatol Assoc, vol.128, pp.14-23, 2017.

E. Cordina-duverger, F. Menegaux, A. Popa, S. Rabstein, V. Harth et al.,

D. C. Fritschi, J. S. Glass, T. C. Heyworth, G. Erren, K. Castano-vinyals et al.,

M. Espinosa, A. Kogevinas, J. J. Grundy, K. J. Spinelli, P. Aronson et al., Night shift work and breast cancer: a pooled analysis of population-based case-control studies with complete work history, Eur J Epidemiol, 2018.

S. Cos, D. Mediavilla, C. Martinez-campa, A. Gonzalez, C. Alonso-gonzalez et al., Exposure to light-at-night increases the growth of DMBA-induced mammary adenocarcinomas in rats, Cancer Lett, vol.235, issue.2, pp.266-271, 2006.

G. Costa, E. Haus, and R. Stevens, Shift work and cancer-considerations on rationale, mechanisms, and epidemiology, Scandinavian journal of work, pp.163-179, 2010.

D. Crawley, F. Chamberlain, H. Garmo, S. Rudman, B. Zethelius et al., A systematic review of the literature exploring the interplay between prostate cancer and type two diabetes mellitus, Ecancermedicalscience, vol.12, p.802, 2018.

L. Cuninkova and S. A. Brown, Peripheral circadian oscillators: interesting mechanisms and powerful tools, Annals of the New York Academy of Sciences, vol.1129, issue.1, pp.358-370, 2008.

O. Cussenot, A. Valeri, P. Berthon, G. Fournier, and P. Mangin, Hereditary prostate cancer and other genetic predispositions to prostate cancer, Urologia internationalis, vol.60, pp.30-34, 1998.

H. Dai, L. Zhang, M. Cao, F. Song, H. Zheng et al., The role of polymorphisms in circadian pathway genes in breast tumorigenesis, Breast Cancer Res Treat, vol.127, issue.2, pp.531-540, 2011.

H. Dai, L. Zhang, M. Cao, F. Song, H. Zheng et al., The role of polymorphisms in circadian pathway genes in breast tumorigenesis, Breast cancer research and treatment, vol.127, issue.2, pp.531-540, 2011.

R. D. Daniels, T. L. Kubale, J. H. Yiin, M. M. Dahm, T. R. Hales et al.,

K. M. Beaumont, L. E. Waters, and . Pinkerton, Mortality and cancer incidence in a pooled cohort of US firefighters from, pp.1950-2009, 2013.

, Occup Environ Med, pp.2013-101662

, Dares Analyses. Les risques professionnels en 2010 : de fortes différences d'exposition selon les secteurs, DARES, 2013.

, Dares Analyses -Publication de la Direction de l'Animation de la Recherche, des Etudes et des Statistiques, vol.62, pp.1-8, 2014.

A. M. De-marzo, V. L. Marchi, J. I. Epstein, and W. G. Nelson, Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis, The American journal of pathology, vol.155, issue.6, pp.1985-1992, 1999.

A. M. De-marzo, Y. Nakai, and W. G. Nelson, Inflammation, atrophy, and prostate carcinogenesis, Urologic Oncology: Seminars and Original Investigations, 2007.

C. De-nunzio, S. Albisinni, S. J. Freedland, L. Miano, L. Cindolo et al., Abdominal obesity as risk factor for prostate cancer diagnosis and high grade disease: a prospective multicenter Italian cohort study, Urologic Oncology: Seminars and Original Investigations, 2013.

A. M. Demarzo, W. G. Nelson, W. B. Isaacs, and J. I. Epstein, Pathological and molecular aspects of prostate cancer, The Lancet, vol.361, issue.9361, pp.955-964, 2003.

E. Diamanti-kandarakis, J. Bourguignon, L. C. Giudice, R. Hauser, G. S. Prins et al., Endocrine-disrupting chemicals: an Endocrine Society scientific statement, Endocrine reviews, vol.30, issue.4, pp.293-342, 2009.

B. A. Dickerman, S. C. Markt, M. Koskenvuo, C. Hublin, E. Pukkala et al., Sleep disruption, chronotype, shift work, and prostate cancer risk and mortality: a 30-year prospective cohort study of Finnish twins, Cancer Causes Control, vol.27, issue.11, pp.1361-1370, 2016.

B. A. Dickerman, S. C. Markt, M. Koskenvuo, E. Pukkala, L. A. Mucci et al., Alcohol intake, drinking patterns, and prostate cancer risk and mortality: a 30-year prospective cohort study of Finnish twins, Cancer Causes Control, vol.27, issue.9, pp.1049-1058, 2016.

A. Discacciati, N. Orsini, and A. Wolk, Body mass index and incidence of localized and advanced prostate cancer-a dose-response meta-analysis of prospective studies, Annals of oncology, vol.23, issue.7, pp.1665-1671, 2012.

J. Du and R. Xu, RORalpha, a potential tumor suppressor and therapeutic target of breast cancer, Int J Mol Sci, vol.13, issue.12, pp.15755-15766, 2012.

N. Eaton, G. Reeves, P. Appleby, and T. Key, Endogenous sex hormones and prostate cancer: a quantitative review of prospective studies, British journal of cancer, vol.80, issue.7, p.930, 1999.

L. Egevad, T. Granfors, L. Karlberg, A. Bergh, and P. Stattin, Prognostic value of the Gleason score in prostate cancer, BJU international, vol.89, issue.6, pp.538-542, 2002.

L. Ercolani, A. Ferrari, C. Mei, C. Parodi, M. Wade et al., Circadian clock: Time for novel anticancer strategies?, Pharmacol Res, vol.100, pp.288-295, 2015.

T. C. Erren, Shift work, cancer and "white-box" epidemiology: Association and causation, Epidemiol Perspect Innov, vol.7, p.11, 2010.

T. C. Erren, Shift work and cancer research: can chronotype predict susceptibility in night-shift and rotating-shift workers?, Occup Environ Med, vol.70, issue.4, pp.283-284, 2013.

T. C. Erren and P. Morfeld, Shift work and cancer research: a thought experiment into a potential chronobiological fallacy of past and perspectives for future epidemiological studies, Neuro Endocrinol Lett, vol.34, issue.4, pp.282-286, 2013.

T. C. Erren, H. G. Pape, R. J. Reiter, and C. Piekarski, Chronodisruption and cancer, Naturwissenschaften, vol.95, issue.5, pp.367-382, 2008.

T. C. Erren and R. J. Reiter, Defining chronodisruption, J Pineal Res, vol.46, issue.3, pp.245-247, 2009.

T. C. Erren and R. J. Reiter, Revisiting chronodisruption: when the physiological nexus between internal and external times splits in humans, Naturwissenschaften, vol.100, issue.4, pp.291-298, 2013.

M. Evangelou, A. Rendon, W. H. Ouwehand, L. Wernisch, and F. Dudbridge, Comparison of methods for competitive tests of pathway analysis, PLoS One, vol.7, issue.7, p.41018, 2012.

, First Findings: Sixth European Working Conditions Survey: Résumé, Publications Office, 2015.

A. Ferrante, D. Gellerman, A. Ay, K. P. Woods, A. M. Filipowicz et al., Diurnal Preference Predicts Phase Differences in Expression of Human Peripheral Circadian Clock Genes, J Circadian Rhythms, vol.13, p.4, 2015.

E. Filipski, F. Delaunay, V. M. King, M. Wu, B. Claustrat et al., Effects of chronic jet lag on tumor progression in mice, Cancer research, vol.64, issue.21, pp.7879-7885, 2004.

E. Filipski, P. F. Innominato, M. Wu, X. Li, S. Iacobelli et al., Effects of light and food schedules on liver and tumor molecular clocks in mice, Journal of the National Cancer Institute, vol.97, issue.7, pp.507-517, 2005.

E. Filipski and F. Lévi, Circadian disruption in experimental cancer processes, Integrative Cancer Therapies, vol.8, issue.4, pp.298-302, 2009.

S. Fonnes, A. M. Donatsky, and I. Gogenur, Expression of core clock genes in colorectal tumour cells compared with normal mucosa: a systematic review of clinical trials, Colorectal Dis, vol.17, issue.4, pp.290-297, 2015.

R. G. Foster and L. Kreitzman, The rhythms of life: what your body clock means to you!, Exp Physiol, vol.99, issue.4, pp.599-606, 2014.

L. Fritschi, D. Glass, J. Heyworth, K. Aronson, J. Girschik et al., Hypotheses for mechanisms linking shiftwork and cancer, Medical hypotheses, vol.77, issue.3, pp.430-436, 2011.

L. Fritschi, D. C. Glass, J. S. Heyworth, K. Aronson, J. Girschik et al., Hypotheses for mechanisms linking shiftwork and cancer, Med Hypotheses, vol.77, issue.3, pp.430-436, 2011.

A. Fu, D. Leaderer, T. Zheng, A. E. Hoffman, R. G. Stevens et al., Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk, Mol Carcinog, vol.51, issue.12, pp.923-929, 2012.

L. Fu and C. C. Lee, The circadian clock: pacemaker and tumour suppressor, Nat Rev Cancer, vol.3, issue.5, pp.350-361, 2003.

L. Fu and C. C. Lee, The circadian clock: pacemaker and tumour suppressor, Nature Reviews Cancer, vol.3, issue.5, pp.350-361, 2003.

L. Fu, H. Pelicano, J. Liu, P. Huang, and C. Lee, The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo, Cell, vol.111, issue.1, pp.41-50, 2002.

C. Gadbois and Y. Queinnec, Travail de nuit, rythmes circadiens et régulation des activités, Le travail humain, vol.47, issue.3, pp.195-225, 1984.

Y. Gan, L. Li, L. Zhang, S. Yan, C. Gao et al., Association between shift work and risk of prostate cancer: a systematic review and metaanalysis of observational studies, Carcinogenesis, vol.39, issue.2, pp.87-97, 2018.

S. M. Gapstur, W. R. Diver, V. L. Stevens, B. D. Carter, L. R. Teras et al., Work schedule, sleep duration, insomnia, and risk of fatal prostate cancer, Am J Prev Med, vol.46, issue.3, 2014.

A. H. Garde, J. Hansen, H. A. Kolstad, A. D. Larsen, and Å. M. Hansen, How do different definitions of night shift affect the exposure assessment of night work?, Chronobiology international, vol.33, issue.6, pp.595-598, 2016.

M. A. Gauger and A. Sancar, Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer, Cancer research, vol.65, issue.15, pp.6828-6834, 2005.

S. Gery and H. Koeffler, The role of circadian regulation in cancer. Cold Spring Harbor symposia on quantitative biology, 2007.

S. Gery, N. Komatsu, L. Baldjyan, A. Yu, D. Koo et al., The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells, Molecular cell, vol.22, issue.3, pp.375-382, 2006.

S. Gery, N. Komatsu, L. Baldjyan, A. Yu, D. Koo et al., The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells, 2006.

, Mol Cell, vol.22, issue.3, pp.375-382

S. Gery, R. Virk, K. Chumakov, A. Yu, and H. Koeffler, The clock gene Per2 links the circadian system to the estrogen receptor, Oncogene, vol.26, issue.57, p.7916, 2007.

E. Giovannucci, Nutritional factors in human cancers, Advances in Nutrition and Cancer, vol.2, pp.29-42, 1999.

R. Golden and R. Kimbrough, Weight of evidence evaluation of potential human cancer risks from exposure to polychlorinated biphenyls: an update based on studies published since 2003, Critical reviews in toxicology, vol.39, issue.4, pp.299-331, 2009.

D. E. Goldgar, D. F. Easton, L. A. Cannon-albright, and M. H. Skolnick, Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands, J Natl Cancer Inst, vol.86, issue.21, pp.1600-1608, 1994.

K. Griffett and T. P. Burris, The mammalian clock and chronopharmacology, Bioorganic & medicinal chemistry letters, vol.23, issue.7, pp.1929-1934, 2013.

C. Gronfier, Physiology of the endogenous circadian clock: From clock genes to clinical applications, Médecine du Sommeil, vol.6, issue.1, pp.3-11, 2009.

P. Grosclaude, A. Belot, L. Marliac, L. Remontet, N. Leone et al., Prostate cancer incidence and mortality trends in France from, Prog Urol, vol.25, issue.9, pp.536-542, 1980.
URL : https://hal.archives-ouvertes.fr/hal-02044767

P. Grosclaude, A. Belot, L. D. Marliac, L. Remontet, N. Leone et al., , 2015.

, Le cancer de la prostate, évolution de l'incidence et de la mortalité en France entre, Progrès en urologie, vol.25, issue.9, pp.536-542, 1980.

J. V. Gross and L. Fritschi, Complementing the Social Jet Lag by considering pristine internal time, Chronobiol Int, vol.34, issue.9, pp.1177-1179, 2017.

J. V. Gross, L. Fritschi, and T. C. Erren, Hypothesis: A perfect day conveys internal time, Med Hypotheses, vol.101, pp.85-89, 2017.

A. Grundy, J. M. Schuetz, A. S. Lai, R. Janoo-gilani, S. Leach et al., Shift work, circadian gene variants and risk of breast cancer, Cancer epidemiology, vol.37, issue.5, pp.606-612, 2013.

D. Gu, S. Li, S. Ben, M. Du, H. Chu et al., Circadian clock pathway genes associated with colorectal cancer risk and prognosis, Arch Toxicol, vol.92, issue.8, pp.2681-2689, 2018.

F. Gu, H. Zhang, P. L. Hyland, S. Berndt, S. M. Gapstur et al.,

S. Amos, H. Bezieau, H. Bickeboller, P. Brenner, J. Brennan et al.,

S. B. Doherty, T. A. Gruber, R. B. Harrison, M. Hayes, R. S. Hoffmeister et al.,

. Caporaso, Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia, Int J Cancer, vol.141, issue.9, pp.1794-1802, 2017.

B. Gurel, M. S. Lucia, I. M. Thompson, P. J. Goodman, C. M. Tangen et al., Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial, Cancer Epidemiology and Prevention Biomarkers, 2014.

F. Halberg, Circadian (about Twenty-four-hour) Rhythms in Experimental Medicine, 1963.

N. Hammar, A. Linnersjö, L. Alfredsson, B. Dammström, M. Johansson et al., Cancer incidence in airline and military pilots in Sweden 1961-1996, Aviation, space, and environmental medicine, vol.73, issue.1, pp.2-7, 2002.

G. P. Hammer, A. Auvinen, B. L. De-stavola, B. Grajewski, M. Gundestrup et al.,

S. Hammar, A. Lagorio, L. Linnersjö, and . Pinkerton, Mortality from cancer and other causes in commercial airline crews: a joint analysis of cohorts from 10 countries, Occupational and environmental medicine, pp.2013-101395, 2014.

G. P. Hammer, A. Auvinen, B. L. De-stavola, B. Grajewski, M. Gundestrup et al.,

S. Hammar, A. Lagorio, L. Linnersjo, E. Pinkerton, V. Pukkala et al.,

H. Storm, T. E. Strand, A. Tzonou, H. Zeeb, and M. Blettner, Mortality from cancer and other causes in commercial airline crews: a joint analysis of cohorts from 10 countries, Occup Environ Med, vol.71, issue.5, pp.313-322, 2014.

G. P. Hammer, K. Emrich, M. Nasterlack, M. Blettner, and M. Yong, Shift Work and Prostate Cancer Incidence in Industrial Workers: A Historical Cohort Study in a German Chemical Company, Dtsch Arztebl Int, vol.112, pp.463-470, 2015.

J. Hansen and C. F. Lassen, Nested case-control study of night shift work and breast cancer risk among women in the Danish military, Occup Environ Med, vol.69, issue.8, pp.551-556, 2012.

L. Hardell, S. O. Andersson, M. Carlberg, L. Bohr, B. Van-bavel et al.,

. Ginman, Adipose tissue concentrations of persistent organic pollutants and the risk of prostate cancer, J Occup Environ Med, vol.48, issue.7, pp.700-707, 2006.

J. L. Harding, J. E. Shaw, K. J. Anstey, R. Adams, B. Balkau et al.,

W. A. Davis, A. Davis, L. Dobson, G. Flicker, J. Giles et al.,

A. Woodward, D. J. Peeters, and . Magliano, Comparison of anthropometric measures as predictors of cancer incidence: A pooled collaborative analysis of 11 Australian cohorts, 2015.

, Int J Cancer, vol.137, issue.7, pp.1699-1708

M. Harma, A. Koskinen, A. Ropponen, S. Puttonen, K. Karhula et al., Validity of self-reported exposure to shift work, Occup Environ Med, vol.74, issue.3, pp.228-230, 2017.

K. Hasakova, M. Vician, R. Reis, M. Zeman, and I. Herichova, Expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates with location of tumor differently, Neoplasma, 2018.

E. L. Haus and M. H. Smolensky, Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation, Sleep medicine reviews, vol.17, issue.4, pp.273-284, 2013.

R. B. Hayes, R. G. Ziegler, G. Gridley, C. Swanson, R. S. Greenberg et al., Dietary factors and risks for prostate cancer among blacks and whites in the United States, Cancer Epidemiology and Prevention Biomarkers, vol.8, issue.1, pp.25-34, 1999.

C. He, S. T. Anand, M. H. Ebell, J. E. Vena, and S. W. Robb, Circadian disrupting exposures and breast cancer risk: a meta-analysis, International archives of occupational and environmental health, vol.88, issue.5, pp.533-547, 2015.

J. Hess-wilson and K. Knudsen, Endocrine disrupting compounds and prostate cancer, Cancer letters, vol.241, issue.1, pp.1-12, 2006.

A. Hida, S. Kitamura, Y. Katayose, M. Kato, H. Ono et al.,

Y. Inoue, M. Kamei, K. Okawa, K. Takahashi, and . Mishima, Screening of clock gene polymorphisms demonstrates association of a PER3 polymorphism with morningnesseveningness preference and circadian rhythm sleep disorder, 2014.

A. E. Hoffman, C. H. Yi, T. Zheng, R. G. Stevens, D. Leaderer et al., CLOCK in breast tumorigenesis: genetic, epigenetic, and transcriptional profiling analyses, Cancer Res, vol.70, issue.4, pp.1459-1468, 2010.

A. E. Hoffman, T. Zheng, Y. Ba, and Y. Zhu, The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response, Mol Cancer Res, vol.6, issue.9, pp.1461-1468, 2008.

A. E. Hoffman, T. Zheng, Y. Ba, and Y. Zhu, The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response, Molecular Cancer Research, vol.6, issue.9, pp.1461-1468, 2008.

A. E. Hoffman, T. Zheng, R. G. Stevens, Y. Ba, Y. Zhang et al.,

. Zhu, Clock-cancer connection in non-Hodgkin's lymphoma: a genetic association study and pathway analysis of the circadian gene cryptochrome 2, Cancer Res, vol.69, issue.8, pp.3605-3613, 2009.

A. E. Hoffman, T. Zheng, C. H. Yi, R. G. Stevens, Y. Ba et al., The core circadian gene Cryptochrome 2 influences breast cancer risk, possibly by mediating hormone signaling, Cancer Prev Res (Phila), vol.3, issue.4, pp.539-548, 2010.

E. Hormones and P. C. Group, Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies, JNCI: Journal of the National Cancer Institute, vol.100, issue.3, pp.170-183, 2008.

J. A. Horne and O. Ostberg, A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms, Int J Chronobiol, vol.4, issue.2, pp.97-110, 1976.

A. W. Hsing, Hormones and prostate cancer: where do we go from here?, 1996.

A. W. Hsing and A. P. Chokkalingam, Prostate cancer epidemiology, Front Biosci, vol.11, issue.5, pp.1388-1413, 2006.

A. W. Hsing, L. W. Chu, and F. Z. Stanczyk, Androgen and prostate cancer: is the hypothesis dead?, Cancer Epidemiology and Prevention Biomarkers, vol.17, issue.10, pp.2525-2530, 2008.

A. W. Hsing and S. S. Devesa, Trends and patterns of prostate cancer: what do they suggest, Epidemiol. Rev, vol.23, issue.3, p.13, 2001.

A. W. Hsing and S. S. Devesa, Trends and patterns of prostate cancer: what do they suggest?, Epidemiologic reviews, vol.23, issue.1, pp.3-13, 2001.

A. W. Hsing, L. C. Sakoda, and S. C. Chua, Obesity, metabolic syndrome, and prostate cancer, The American journal of clinical nutrition, vol.86, issue.3, pp.843-857, 2007.

C. M. Hsu, S. F. Lin, C. T. Lu, P. M. Lin, and M. Y. Yang, Altered expression of circadian clock genes in head and neck squamous cell carcinoma, Tumour Biol, vol.33, issue.1, pp.149-155, 2012.

Y. Hu, A. Shmygelska, D. Tran, N. Eriksson, J. Y. Tung et al., GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person, Nat Commun, vol.7, p.10448, 2016.

H. Hua, Y. Wang, C. Wan, Y. Liu, B. Zhu et al., Circadian gene mPer2 overexpression induces cancer cell apoptosis, Cancer science, vol.97, issue.7, pp.589-596, 2006.

S. Ijaz, J. Verbeek, A. Seidler, M. L. Lindbohm, A. Ojajarvi et al., Night-shift work and breast cancer--a systematic review and meta-analysis, Scand J Work Environ Health, vol.39, issue.5, pp.431-447, 2013.

, Les cancers en France, Collection Les Données, 2017.

, Le travail de nuit et le travail posté : Quels effets ? Quelle prévention ?, INRS, 2018.

G. Jenster, The role of the androgen receptor in the development and progression of prostate cancer, Semin Oncol, vol.26, issue.4, pp.407-421, 1999.

L. Jia, M. S. Soengas, and Y. Sun, ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence, Cancer Res, vol.69, issue.12, pp.4974-4982, 2009.

L. Jia and Y. Sun, SCF E3 ubiquitin ligases as anticancer targets, Curr Cancer Drug Targets, vol.11, issue.3, pp.347-356, 2011.

Y. Jia, Y. Lu, K. Wu, Q. Lin, W. Shen et al., Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies, Cancer Epidemiol, vol.37, issue.3, pp.197-206, 2013.

W. Jiang, S. Zhao, X. Jiang, E. Zhang, G. Hu et al.,

L. Wang, R. Yang, and . Wan, The circadian clock gene Bmal1 acts as a potential antioncogene in pancreatic cancer by activating the p53 tumor suppressor pathway, Cancer Lett, vol.371, issue.2, pp.314-325, 2016.

H. S. Jim, H. Y. Lin, J. P. Tyrer, K. Lawrenson, J. Dennis et al.,

M. W. Bean, M. Beckmann, L. Bisogna, N. Bjorge, L. A. Bogdanova et al.,

M. Cunningham, C. Cybulski, A. Dansonka-mieszkowska, A. Bois, E. Despierre et al.,

A. Doherty, T. Dork, M. Durst, D. F. Easton, D. M. Eccles et al.,

B. L. Fasching, Y. T. Fridley, A. Gao, G. G. Gentry-maharaj, R. Giles et al.,

J. Goodman, P. Gronwald, H. N. Harter, A. Hasmad, F. Hein et al.,

C. K. Hillemanns, E. Hogdall, S. Hogdall, E. S. Hosono, A. Iversen et al.,

B. Y. Ji, M. Karlan, L. A. Kellar, C. Kiemeney, S. K. Krakstad et al.,

D. Vierkant, S. Lambrechts, N. D. Lambrechts, A. W. Le, S. Lee et al.,

A. Levine, D. Liang, B. K. Lim, J. Lissowska, K. Lu et al.,

V. Matsuo, J. R. Mcguire, I. Mclaughlin, U. Mcneish, R. L. Menon et al.,

K. B. Thomsen, R. B. Moysich, H. Ness, U. Nevanlinna, K. Eilber et al.,

E. Poole, H. A. Schernhammer, B. Risch, M. A. Rosen, J. H. Rossing et al.,

B. Runnebaum, I. K. Rzepecka, H. B. Salvesen, I. Schwaab, X. O. Shu et al.,

H. Siddiqui, M. C. Song, B. Southey, L. Spiewankiewicz, S. H. Sucheston-campbell et al.,

P. J. Terry, I. L. Thompson, S. S. Tangen, A. M. Tworoger, I. Van-altena et al.,

T. A. Pharoah, C. M. Sellers, and . Phelan, Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC), J Genet Genome Res, vol.2, issue.2, 2015.

L. Johns and R. Houlston, A systematic review and meta-analysis of familial prostate cancer risk, BJU international, vol.91, issue.9, pp.789-794, 2003.

M. Kakizaki, K. Inoue, S. Kuriyama, T. Sone, K. Matsuda-ohmori et al.,

. Tsuji, Sleep duration and the risk of prostate cancer: the Ohsaki Cohort Study, Br J Cancer, vol.99, issue.1, pp.176-178, 2008.

B. B. Kamdar, A. I. Tergas, F. J. Mateen, N. H. Bhayani, and J. Oh, Night-shift work and risk of breast cancer: a systematic review and meta-analysis, Breast cancer research and treatment, vol.138, issue.1, pp.291-301, 2013.

T. Kantermann, H. Sung, and H. J. Burgess, Comparing the Morningness-Eveningness Questionnaire and Munich ChronoType Questionnaire to the Dim Light Melatonin Onset, J Biol Rhythms, vol.30, issue.5, pp.449-453, 2015.

T. Karantanos, G. Theodoropoulos, D. Pektasides, and M. Gazouli, Clock genes: their role in colorectal cancer, World Journal of Gastroenterology: WJG, vol.20, issue.8, 1986.

D. Katzenberg, T. Young, L. Finn, L. Lin, D. P. King et al., A CLOCK polymorphism associated with human diurnal preference, Sleep, vol.21, issue.6, pp.569-576, 1998.

F. C. Kelleher, A. Rao, and A. Maguire, Circadian molecular clocks and cancer, Cancer Lett, vol.342, issue.1, pp.9-18, 2014.

J. E. Keller-byrne, S. A. Khuder, and E. A. Schaub, Meta-analyses of prostate cancer and farming, American journal of industrial medicine, vol.31, issue.5, pp.580-586, 1997.

N. M. Kettner, C. A. Katchy, and L. Fu, Circadian gene variants in cancer, Annals of medicine, vol.46, issue.4, pp.208-220, 2014.

K. L. Knutson and M. Schantz, Associations between chronotype, morbidity and mortality in the UK Biobank cohort, Chronobiology international, pp.1-9, 2018.

C. H. Ko and J. S. Takahashi, Molecular components of the mammalian circadian clock, Human molecular genetics, vol.15, issue.suppl_2, pp.271-277, 2006.

M. Kogevinas, A. Espinosa, A. Castelló, I. Gómez-acebo, M. Guevara et al.,

R. Alguacil, V. Peiro, and . Moreno, Effect of mistimed eating patterns on breast and prostate cancer risk (MCC-Spain Study), International journal of cancer, 2018.

K. Kogi, Improving shift workers' health and tolerance to shiftwork: recent advances, Applied Ergonomics, vol.27, issue.1, pp.5-8, 1996.

L. Kolonel, M. Hinds, and J. Hankin, Cancer patterns among migrant and native-born Japanese in Hawaii in relation to smoking, drinking, and dietary habits, Genetics and environmental factors in experimental and human cancer, pp.327-340, 1980.

L. N. Kolonel, Fat, meat, and prostate cancer, Epidemiologic reviews, vol.23, issue.1, pp.72-81, 2001.

L. N. Kolonel, J. Hankin, J. Lee, S. Chu, A. Nomura et al., Nutrient intakes in relation to cancer incidence in Hawaii, British journal of cancer, vol.44, issue.3, p.332, 1981.

L. N. Kolonel, J. H. Hankin, and A. M. Nomura, Multiethnic studies of diet, nutrition and cancer in Hawaii, Diet, pp.29-40, 1986.

L. N. Kolonel, A. M. Nomura, and R. V. Cooney, Dietary fat and prostate cancer: current status, Journal of the National Cancer Institute, vol.91, issue.5, pp.414-428, 1999.

R. V. Kondratov, V. Y. Gorbacheva, and M. P. Antoch, The role of mammalian circadian proteins in normal physiology and genotoxic stress responses, Curr Top Dev Biol, vol.78, pp.173-216, 2007.

S. Krstev, D. Baris, P. A. Stewart, R. B. Hayes, A. Blair et al., Risk for prostate cancer by occupation and industry: A 24-state death certificate study, American journal of industrial medicine, vol.34, issue.5, pp.413-420, 1998.

W. Krugluger, A. Brandstaetter, E. Kallay, J. Schueller, E. Krexner et al.,

S. Cross, Regulation of genes of the circadian clock in human colon cancer: reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors, Cancer Res, vol.67, issue.16, pp.7917-7922, 2007.

T. Kubo, I. Oyama, T. Nakamura, M. Kunimoto, K. Kadowaki et al., Industry-based retrospective cohort study of the risk of prostate cancer among rotating-shift workers, Int J Urol, vol.18, issue.3, pp.206-211, 2011.

T. Kubo, K. Ozasa, K. Mikami, K. Wakai, Y. Fujino et al.,

M. Suzuki, M. Mori, F. Washio, Y. Sakauchi, T. Ito et al., , 2006.

, Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study, Am J Epidemiol, vol.164, issue.6, pp.549-555

T. A. Lahti, T. Partonen, P. Kyyrönen, T. Kauppinen, and E. Pukkala, Night-time work predisposes to non-Hodgkin lymphoma, International Journal of Cancer, vol.123, issue.9, pp.2148-2151, 2008.

E. W. Lamont, F. O. James, D. B. Boivin, and N. Cermakian, From circadian clock gene expression to pathologies, Sleep Med, vol.8, issue.6, pp.547-556, 2007.

C. C. Lee, Tumor suppression by the mammalian Period genes, Cancer Causes & Control, vol.17, issue.4, pp.525-530, 2006.

I. Lee, H. D. Sesso, J. Chen, and R. S. Paffenbarger, Does physical activity play a role in the prevention of prostate cancer?, Epidemiologic reviews, vol.23, issue.1, p.132, 2001.

S. Lee, L. A. Donehower, A. J. Herron, D. D. Moore, and L. Fu, Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice, PLoS One, vol.5, issue.6, p.10995, 2010.

Y. S. Lee, C. C. Hsu, S. F. Weng, H. J. Lin, J. J. Wang et al., Cancer Incidence in Physicians: A Taiwan National Population-based Cohort Study, Medicine (Baltimore), vol.94, issue.47, p.2079, 2015.

M. F. Leitzmann, M. J. Stampfer, J. Ma, J. M. Chan, G. A. Colditz et al.,

. Giovannucci, Aspirin use in relation to risk of prostate cancer, Cancer Epidemiology and Prevention Biomarkers, vol.11, issue.10, pp.1108-1111, 2002.

Z. Lengyel, C. Lovig, S. Kommedal, R. Keszthelyi, G. Szekeres et al.,

. Nagy, Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors, Tumour Biol, vol.34, issue.2, pp.811-819, 2013.

J. Li, K. Humphreys, T. Heikkinen, K. Aittomäki, C. Blomqvist et al.,

M. J. Ahmed, J. W. Hooning, and . Martens, A combined analysis of genome-wide association studies in breast cancer, Breast cancer research and treatment, vol.126, issue.3, pp.717-727, 2011.

J. Li, K. Humphreys, T. Heikkinen, K. Aittomaki, C. Blomqvist et al.,

M. J. Ahmed, J. W. Hooning, A. M. Martens, L. Van-den-ouweland, A. Alfredsson et al., A combined analysis of genome-wide association studies in breast cancer, Breast Cancer Res Treat, vol.126, issue.3, pp.717-727, 2011.

P. Lichtenstein, N. V. Holm, P. K. Verkasalo, A. Iliadou, J. Kaprio et al., Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, New England journal of medicine, vol.343, issue.2, pp.78-85, 2000.

J. A. Lie, H. Kjuus, S. Zienolddiny, A. Haugen, R. G. Stevens et al., Night work and breast cancer risk among Norwegian nurses: assessment by different exposure metrics, Am J Epidemiol, vol.173, issue.11, pp.1272-1279, 2011.

D. W. Lin, L. M. Fitzgerald, R. Fu, E. M. Kwon, S. L. Zheng et al.,

J. Isaacs, E. A. Xu, Z. Ostrander, H. Feng, J. L. Gronberg et al., Genetic variants in the LEPR, CRY1, RNASEL, IL4, and ARVCF genes are prognostic markers of prostate cancerspecific mortality, Cancer Epidemiol Biomarkers Prev, vol.20, issue.9, pp.1928-1936, 2011.

R. J. Macinnis and D. R. English, Body size and composition and prostate cancer risk: systematic review and meta-regression analysis, Cancer causes & control, vol.17, issue.8, pp.989-1003, 2006.

R. Mahajan, A. Blair, C. F. Lynch, P. Schroeder, J. A. Hoppin et al., Fonofos exposure and cancer incidence in the agricultural health study, Environmental health perspectives, vol.114, issue.12, p.1838, 2006.

R. Mahajan, M. R. Bonner, J. A. Hoppin, and M. C. Alavanja, Phorate exposure and incidence of cancer in the agricultural health study, Environmental Health Perspectives, vol.114, issue.8, p.1205, 2006.

J. Mancio, C. Leal, M. Ferreira, P. Norton, and N. Lunet, Does the association of prostate cancer with night-shift work differ according to rotating vs. fixed schedule? A systematic review and meta-analysis, Prostate cancer and prostatic diseases, 2018.

L. Mao, R. T. Dauchy, D. E. Blask, L. M. Slakey, S. Xiang et al.,

J. P. Brainard, T. Hanifin, T. T. Frasch, S. M. Duplessis, and . Hill, Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3beta, Mol Endocrinol, vol.26, issue.11, pp.1808-1820, 2012.

S. C. Markt, E. E. Flynn-evans, U. A. Valdimarsdottir, L. G. Sigurdardottir, R. M. Tamimi et al.,

S. Batista, S. W. Haneuse, M. Lockley, K. M. Stampfer, C. A. Wilson et al.,

A. Mucci, Sleep Duration and Disruption and Prostate Cancer Risk: a 23-Year Prospective Study, Cancer Epidemiology Biomarkers & Prevention, vol.25, issue.2, pp.302-308, 2015.

S. C. Markt, A. Grotta, O. Nyren, H. O. Adami, L. A. Mucci et al., Insufficient Sleep and Risk of Prostate Cancer in a Large Swedish Cohort, Sleep, vol.38, issue.9, pp.1405-1410, 2015.

S. C. Markt, U. A. Valdimarsdottir, I. M. Shui, L. G. Sigurdardottir, J. R. Rider et al.,

S. Batista, E. Haneuse, S. W. Flynn-evans, C. A. Lockley, M. J. Czeisler et al.,

A. V. Harris, V. Smith, S. Gudnason, P. Lindstrom, L. A. Kraft et al., Circadian clock genes and risk of fatal prostate cancer, Cancer Causes Control, vol.26, issue.1, pp.25-33, 2015.

J. R. Marshall, Diet and prostate cancer prevention, World journal of urology, vol.30, issue.2, pp.157-165, 2012.

T. Matsuo, S. Yamaguchi, S. Mitsui, A. Emi, F. Shimoda et al., Control mechanism of the circadian clock for timing of cell division in vivo, Science, vol.302, issue.5643, pp.255-259, 2003.

G. Mazzoccoli, A. Panza, M. R. Valvano, O. Palumbo, M. Carella et al., Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients, Chronobiol Int, vol.28, issue.10, pp.841-851, 2011.

S. P. Megdal, C. H. Kroenke, F. Laden, E. Pukkala, and E. S. Schernhammer, Night work and breast cancer risk: a systematic review and meta-analysis, European Journal of Cancer, vol.41, issue.13, pp.2023-2032, 2005.

J. Mendoza, Circadian clocks: setting time by food, J Neuroendocrinol, vol.19, issue.2, pp.127-137, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00192485

F. Menegaux, T. Truong, A. Anger, E. Cordina-duverger, F. Lamkarkach et al., Night work and breast cancer: A population-based casecontrol study in France (the CECILE study), International Journal of Cancer, vol.132, issue.4, pp.924-931, 2013.

T. Merbitz-zahradnik and E. Wolf, How is the inner circadian clock controlled by interactive clock proteins?: Structural analysis of clock proteins elucidates their physiological role, FEBS Lett, vol.589, issue.14, pp.1516-1529, 2015.

I. Merikanto, T. Lahti, H. Puolijoki, M. Vanhala, M. Peltonen et al., Associations of chronotype and sleep with cardiovascular diseases and type 2 diabetes, Chronobiology international, vol.30, issue.4, pp.470-477, 2013.

K. Mishima, T. Tozawa, K. Satoh, H. Saitoh, and Y. Mishima, The 3111T/C polymorphism of hClock is associated with evening preference and delayed sleep timing in a Japanese population sample, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, vol.133, issue.1, pp.101-104, 2005.

S. Mocellin, S. Tropea, C. Benna, and C. R. Rossi, Circadian pathway genetic variation and cancer risk: evidence from genome-wide association studies, BMC medicine, vol.16, issue.1, p.20, 2018.

T. Momma, H. Okayama, M. Saitou, H. Sugeno, N. Yoshimoto et al.,

. Takenoshita, Expression of circadian clock genes in human colorectal adenoma and carcinoma, Oncol Lett, vol.14, issue.5, pp.5319-5325, 2017.

G. M. Monsees, P. Kraft, S. E. Hankinson, D. J. Hunter, and E. S. Schernhammer, , 2012.

, Circadian genes and breast cancer susceptibility in rotating shift workers, Int J Cancer, vol.131, issue.11, pp.2547-2552

N. K. Mukhopadhyay, A. S. Ferdinand, L. Mukhopadhyay, B. Cinar, M. Lutchman et al., Unraveling androgen receptor interactomes by an arraybased method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor, Exp Cell Res, vol.312, pp.3782-3795, 2006.

L. Multigner, L. Brureau, and P. Blanchet, Le cancer de la prostate aux Antilles françaises : état des lieux, Bull Epidemiol Hebd, 2016.

L. Nadon, J. Siemiatycki, R. Dewar, D. Krewski, and M. Gerin, Cancer risk due to occupational exposure to polycyclic aromatic hydrocarbons, Am J Ind Med, vol.28, issue.3, pp.303-324, 1995.

J. Nelson and R. E. Harris, Inverse association of prostate cancer and non-steroidal antiinflammatory drugs (NSAIDs): results of a case-control study, Oncology reports, vol.7, issue.1, pp.169-239, 2000.

A. E. Norrish, L. R. Ferguson, M. G. Knize, J. S. Felton, S. J. Sharpe et al., , 1999.

, Heterocyclic amine content of cooked meat and risk of prostate cancer, Journal of the National Cancer Institute, vol.91, issue.23, pp.2038-2044

A. E. Norrish, R. T. Jackson, and C. U. Mcrae, Non-steroidal anti-inflammatory drugs and prostate cancer progression, International journal of cancer, vol.77, issue.4, pp.511-515, 1998.

N. N. Nupponen, M. J. Wallén, D. Ponciano, C. M. Robbins, T. L. Tammela et al., Mutational analysis of susceptibility genes RNASEL/HPC1, ELAC2/HPC2, and MSR1 in sporadic prostate cancer, Genes, Chromosomes and Cancer, vol.39, issue.2, pp.119-125, 2004.

E. A. Ostrander and J. L. Stanford, Genetics of prostate cancer: too many loci, too few genes, The American Journal of Human Genetics, vol.67, issue.6, pp.1367-1375, 2000.

K. Papantoniou, G. Castano-vinyals, A. Espinosa, N. Aragones, B. Perez-gomez et al., Night shift work, chronotype and prostate cancer risk in the MCC-Spain case-control study, Int J Cancer, vol.137, issue.5, pp.1147-1157, 2015.

K. Papantoniou, G. Castaño-vinyals, A. Espinosa, N. Aragonés, B. Pérez-gómez et al., Night shift work, chronotype and prostate cancer risk in the MCC-Spain case-control study, International Journal of Cancer, 2015.

M. E. Parent, M. El-zein, M. C. Rousseau, J. Pintos, and J. Siemiatycki, Night work and the risk of cancer among men, Am J Epidemiol, vol.176, issue.9, pp.751-759, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-01007614

P. Pavageau, Au-delà des horaires, le poids du travail sur la santé des travailleurs postés: étude ergonomique auprès des personnels de surveillance des établissements pénitentiaires, 2005.

D. S. Pereira, S. Tufik, F. M. Louzada, A. A. Benedito-silva, A. R. Lopez et al.,

V. Korczak, M. D'almeida, and . Pedrazzoli, Association of the length polymorphism in the human Per3 gene with the delayed sleep-phase syndrome: does latitude have an influence upon it?, Sleep, vol.28, issue.1, pp.29-32, 2005.

A. Perez-cornago, P. N. Appleby, T. Pischon, K. K. Tsilidis, A. Tjønneland et al., Tall height and obesity are associated with an increased risk of aggressive prostate cancer: results from the EPIC cohort study, BMC medicine, vol.15, issue.1, p.115, 2017.

M. Peyromaure, P. Beuzeboc, L. Salomon, P. Richaud, P. Coloby et al., Le dépistage du cancer de la prostate en 2009: mise au point du comité de cancérologie de l'Association française d'urologie, Progrès en urologie, vol.20, issue.1, pp.17-23, 2010.

K. J. Pienta and P. S. Esper, Risk factors for prostate cancer, Annals of internal medicine, vol.118, issue.10, pp.793-803, 1993.

P. G. Pilie, V. N. Giri, and K. A. Cooney, HOXB13 and other high penetrant genes for prostate cancer, Asian J Androl, vol.18, issue.4, pp.530-532, 2016.

E. A. Platz, S. Rohrmann, J. D. Pearson, M. M. Corrada, D. J. Watson et al.,

E. J. Landis, H. B. Metter, and . Carter, Nonsteroidal anti-inflammatory drugs and risk of prostate cancer in the Baltimore Longitudinal Study of Aging, Cancer Epidemiology and Prevention Biomarkers, vol.14, issue.2, pp.390-396, 2005.

E. M. Poole, E. S. Schernhammer, and S. S. Tworoger, Rotating night shift work and risk of ovarian cancer, Cancer Epidemiology Biomarkers & Prevention, vol.20, issue.5, pp.934-938, 2011.

G. S. Prins, Endocrine disruptors and prostate cancer risk, Endocrine-Related Cancer, vol.15, issue.3, pp.649-656, 2008.

S. Prunier-poulmaire, C. Gadbois, and S. Volkoff, Combined effects of shift systems and work requirements on customs officers, Scandinavian journal of work, pp.134-140, 1998.

E. Pukkala, R. Aspholm, A. Auvinen, H. Eliasch, M. Gundestrup et al., Incidence of cancer among Nordic airline pilots over five decades: occupational cohort study, Bmj, vol.325, issue.7364, p.567, 2002.

E. Pukkala, R. Aspholm, A. Auvinen, H. Eliasch, M. Gundestrup et al., Cancer incidence among 10,211 airline pilots: a Nordic study, Aviat Space Environ Med, vol.74, issue.7, pp.699-706, 2003.

E. Pukkala, M. Helminen, T. Haldorsen, N. Hammar, K. Kojo et al., Cancer incidence among Nordic airline cabin crew, Int J Cancer, vol.131, issue.12, pp.2886-2897, 2012.

E. Pukkala, J. I. Martinsen, E. Lynge, H. K. Gunnarsdottir, P. Sparen et al., Occupation and cancer -follow-up of 15 million people in five Nordic countries, Acta Oncol, vol.48, issue.5, pp.646-790, 2009.

E. Pukkala, J. I. Martinsen, E. Weiderpass, K. Kjaerheim, E. Lynge et al., Cancer incidence among firefighters: 45 years of follow-up in five Nordic countries, Occup Environ Med, vol.71, issue.6, pp.398-404, 2014.

S. Purcell, B. Neale, K. Todd-brown, L. Thomas, M. A. Ferreira et al., PLINK: a tool set for whole-genome association and population-based linkage analyses, Am J Hum Genet, vol.81, issue.3, pp.559-575, 2007.

S. Rabstein, V. Harth, C. Justenhoven, B. Pesch, S. Plottner et al., Polymorphisms in circadian genes, night work and breast cancer: results from the GENICA study, Chronobiol Int, vol.31, issue.10, pp.1115-1122, 2014.

S. Rabstein, V. Harth, C. Justenhoven, B. Pesch, S. Plöttner et al., , 2014.

, Polymorphisms in circadian genes, night work and breast cancer: Results from the GENICA study, Chronobiology International, vol.31, issue.10, pp.1115-1122

V. Rafnsson, J. Hrafnkelsson, and H. Tulinius, Incidence of cancer among commercial airline pilots, Occupational and environmental medicine, vol.57, issue.3, pp.175-179, 2000.

H. P. Rahman, J. Hofland, and P. A. Foster, In touch with your feminine side: how oestrogen metabolism impacts prostate cancer, Endocr Relat Cancer, vol.23, issue.6, pp.249-266, 2016.

S. Rana and S. Mahmood, Circadian rhythm and its role in malignancy, J Circadian Rhythms, vol.8, p.3, 2010.

D. Rao, H. Yu, Y. Bai, X. Zheng, and L. Xie, Does night-shift work increase the risk of prostate cancer? a systematic review and meta-analysis, Onco Targets Ther, vol.8, pp.2817-2826, 2015.

A. B. Reddy and J. S. O'neill, Healthy clocks, healthy body, healthy mind, Trends in cell biology, vol.20, issue.1, pp.36-44, 2010.

A. Reinberg, A. Bicakova-rocher, J. Nouguier, A. Gorceix, M. Mechkouri et al.,

. Ashkenazi, Circadian rhythm period in reaction time to light signals: difference between right-and left-hand side, Cognitive brain research, vol.6, issue.2, pp.135-140, 1997.

A. Reinberg, M. Riedel, E. Brousse, N. L. Floc'h, R. Clarisse et al.,

M. Smolensky, S. Marlot, and . Berrez, Circadian Time Organization of Professional Firemen: Desynchronization-Tau Differing from 24.0 Hours-Documented by Longitudinal Self-assessment of 16 Variables, Chronobiology international, vol.30, issue.8, pp.1050-1065, 2013.

A. Reinberg, M. H. Smolensky, M. Riedel, Y. Touitou, N. L. Floc'h et al., Chronobiologic perspectives of black time-Accident risk is greatest at night: An opinion paper, Chronobiology international, vol.32, issue.7, pp.1005-1018, 2015.

A. Reinberg and Y. Touitou, Synchronization and dyschronism of human circadian rhythms, Pathologie-biologie, vol.44, issue.6, pp.487-495, 1996.

D. Relles, J. Sendecki, G. Chipitsyna, T. Hyslop, C. J. Yeo et al., Circadian gene expression and clinicopathologic correlates in pancreatic cancer, J Gastrointest Surg, vol.17, issue.3, pp.443-450, 2013.

H. Rennert, C. M. Zeigler-johnson, K. Addya, M. J. Finley, A. H. Walker et al.,

A. Leonard, S. B. Wein, T. R. Malkowicz, and . Rebbeck, Association of susceptibility alleles in ELAC2/HPC2, RNASEL/HPC1, and MSR1 with prostate cancer severity in European American and African American men, Cancer Epidemiology and Prevention Biomarkers, vol.14, issue.4, pp.949-957, 2005.

S. M. Reppert and D. R. Weaver, Coordination of circadian timing in mammals, Nature, vol.418, issue.6901, pp.935-941, 2002.

J. M. Ritchie, S. L. Vial, L. J. Fuortes, H. Guo, V. E. Reedy et al., , 2003.

, Organochlorines and risk of prostate cancer, Journal of occupational and environmental medicine, vol.45, issue.7, pp.692-702

J. M. Ritchie, S. L. Vial, L. J. Fuortes, L. W. Robertson, H. Guo et al., Comparison of proposed frameworks for grouping polychlorinated biphenyl congener data applied to a case-control pilot study of prostate cancer, Environmental research, vol.98, issue.1, pp.104-113, 2005.

A. W. Roddam, N. E. Allen, P. Appleby, T. J. Key, L. Ferrucci et al., Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies, Annals of internal medicine, vol.149, issue.7, pp.461-471, 2008.

C. Rodriguez, M. L. Mccullough, A. M. Mondul, E. J. Jacobs, D. Fakhrabadi-shokoohi et al.,

M. J. Giovannucci, E. E. Thun, and . Calle, Calcium, dairy products, and risk of prostate cancer in a prospective cohort of United States men, Cancer Epidemiology and Prevention Biomarkers, vol.12, issue.7, pp.597-603, 2003.

O. D. Roe, E. Anderssen, E. Helge, C. H. Pettersen, K. S. Olsen et al., Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype, PLoS One, vol.4, issue.8, p.6554, 2009.

T. Roenneberg, T. Kuehnle, M. Juda, T. Kantermann, K. Allebrandt et al., Epidemiology of the human circadian clock, Sleep Med Rev, vol.11, issue.6, pp.429-438, 2007.

T. Roenneberg, A. Wirz-justice, and M. Merrow, Life between clocks: daily temporal patterns of human chronotypes, J Biol Rhythms, vol.18, issue.1, pp.80-90, 2003.

M. D. Román, C. Niclis, L. R. Aballay, and M. Josefina, Do Exposure to Arsenic, Occupation and Diet Have Synergistic Effects on Prostate Cancer Risk?, Asian Pacific journal of cancer prevention: APJCP, vol.19, issue.6, pp.1495-1501, 2018.

R. K. Ross, H. Shimizu, A. Paganini-hill, G. Honda, and B. E. Henderson, Case-control studies of prostate cancer in blacks and whites in southern California, Journal of the National Cancer Institute, vol.78, issue.5, pp.869-874, 1987.

J. Rutenfrantz and P. Knauth, Night and Shiftwork: Longterm Effects and Their Prevention, 1986.

S. Saha and P. Sassone-corsi, Circadian clock and breast cancer: a molecular link, Cell Cycle, vol.6, issue.11, pp.1329-1331, 2007.

I. B. Saksvik, B. Bjorvatn, H. Hetland, G. M. Sandal, and S. Pallesen, Individual differences in tolerance to shift work--a systematic review, Sleep Med Rev, vol.15, issue.4, pp.221-235, 2011.

C. A. Salinas, E. M. Kwon, L. M. Fitzgerald, Z. Feng, P. S. Nelson et al.,

L. Stanford, Use of aspirin and other nonsteroidal antiinflammatory medications in relation to prostate cancer risk, Am J Epidemiol, vol.172, issue.5, pp.578-590, 2010.

A. A. Sandberg, Endocrine control and physiology of the prostate, The prostate, vol.1, issue.2, pp.169-184, 1980.

E. S. Schernhammer, D. Feskanich, G. Liang, and J. Han, Rotating night-shift work and lung cancer risk among female nurses in the United States, American journal of epidemiology, vol.178, issue.9, pp.1434-1441, 2013.

E. S. Schernhammer, F. Laden, F. E. Speizer, W. C. Willett, D. J. Hunter et al., Night-shift work and risk of colorectal cancer in the nurses' health study, Journal of the National Cancer Institute, vol.95, issue.11, pp.825-828, 2003.

A. Scherpereel and S. Dehette, Nouvelle classification internationale TNM (7e édition) du cancer pulmonaire: explications et implications pratiques, Revue des Maladies Respiratoires, vol.25, pp.66-68, 2008.

F. H. Schröder, J. Hugosson, M. J. Roobol, T. L. Tammela, M. Zappa et al., Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up, The Lancet, vol.384, issue.9959, pp.2027-2035, 2014.

J. Schwartzbaum, A. Ahlbom, and M. Feychting, Cohort study of cancer risk among male and female shift workers, Scand J Work Environ Health, vol.33, issue.5, pp.336-343, 2007.

A. Seidler, H. Heiskel, R. Bickeboller, and G. Elsner, Association between diesel exposure at work and prostate cancer, Scand J Work Environ Health, vol.24, issue.6, pp.486-494, 1998.

S. Sharma-wagner, A. P. Chokkalingam, H. S. Malker, B. Stone, J. K. Mclaughlin et al., Occupation and prostate cancer risk in Sweden, Journal of occupational and environmental medicine, vol.42, issue.5, pp.517-525, 2000.

Y. Shub, I. E. Ashkenazi, and A. Reinberg, Differences between left-and right-hand reaction time rhythms: indications of shifts in strategies of human brain activity1, Cognitive brain research, vol.6, issue.2, pp.141-146, 1997.

B. Srour, S. Plancoulaine, V. A. Andreeva, P. Fassier, C. Julia et al., Circadian nutritional behaviours and cancer risk: New insights from the NutriNet-sante prospective cohort study: Disclaimers, Int J Cancer, 2018.

G. D. Steinberg, B. S. Carter, T. H. Beaty, B. Childs, and P. C. Walsh, Family history and the risk of prostate cancer, The prostate, vol.17, issue.4, pp.337-347, 1990.

R. G. Stevens, Electric power use and breast cancer: a hyptothesis, Am. J. Epidemiol, issue.4, p.125, 1987.

R. G. Stevens, D. E. Blask, G. C. Brainard, J. Hansen, S. W. Lockley et al.,

. Reinlib, Meeting report: the role of environmental lighting and circadian disruption in cancer and other diseases, pp.1357-1362, 2007.

R. G. Stevens, J. Hansen, G. Costa, E. Haus, T. Kauppinen et al.,

M. H. Davis, L. Frings-dresen, M. Fritschi, K. Kogevinas, J. A. Kogi et al., Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report, Occup Environ Med, vol.68, issue.2, pp.154-162, 2011.

K. Straif, R. Baan, Y. Grosse, B. Secretan, F. E. Ghissassi et al., Carcinogenicity of shift-work, painting, and fire-fighting, The lancet oncology, vol.8, issue.12, pp.1065-1066, 2007.

M. Stratmann and U. Schibler, Properties, entrainment, and physiological functions of mammalian peripheral oscillators, Journal of biological rhythms, vol.21, issue.6, pp.494-506, 2006.

J. Taillard, P. Philip, J. Chastang, and B. Bioulac, Validation of Horne and Ostberg morningness-eveningness questionnaire in a middle-aged population of French workers, Journal of biological rhythms, vol.19, issue.1, pp.76-86, 2004.

S. H. Tan, G. Petrovics, and S. Srivastava, Prostate Cancer Genomics: Recent Advances and the Prevailing Underrepresentation from Racial and Ethnic Minorities, Int J Mol Sci, vol.19, issue.4, 2018.

P. D. Terry, T. E. Rohan, and A. Wolk, Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence, The American journal of clinical nutrition, vol.77, issue.3, pp.532-543, 2003.

M. J. Thun, M. M. Namboodiri, E. E. Calle, W. D. Flanders, and C. W. Heath, Aspirin use and risk of fatal cancer, Cancer research, vol.53, issue.6, pp.1322-1327, 1993.

C. Today, Prostate cancer : estimated incidence, mortality and prevalence worldwide, 2018.

Y. Touitou, O. Coste, G. Dispersyn, and L. Pain, Disruption of the circadian system by environmental factors: effects of hypoxia, magnetic fields and general anesthetics agents, Advanced drug delivery reviews, vol.62, issue.9, pp.928-945, 2010.

R. C. Travis, A. Balkwill, G. K. Fensom, P. N. Appleby, G. K. Reeves et al.,

R. Gathani, J. Peto, and . Green, Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies, Journal of the National Cancer Institute, vol.108, issue.12, p.169, 2016.

T. Truong, B. Liquet, F. Menegaux, S. Plancoulaine, P. Laurent-puig et al., Breast cancer risk, nightwork, and circadian clock gene polymorphisms, Endocrine-related cancer, vol.21, issue.4, pp.629-638, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01097160

T. Truong, B. Liquet, F. Menegaux, S. Plancoulaine, P. Laurent-puig et al., Breast cancer risk, nightwork, and circadian clock gene polymorphisms, Endocr Relat Cancer, vol.21, issue.4, pp.629-638, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01097160

L. A. Tse, P. M. Lee, W. M. Ho, A. T. Lam, M. K. Lee et al., Bisphenol A and other environmental risk factors for prostate cancer in Hong Kong, Environ Int, vol.107, pp.1-7, 2017.

H. Tsuda, A. Naito, C. K. Kim, K. Fukamachi, H. Nomoto et al., , 2003.

, Carcinogenesis and its modification by environmental endocrine disruptors: in vivo experimental and epidemiological findings, Japanese journal of clinical oncology, vol.33, issue.6, pp.259-270

K. Ünsal-kaçmaz, T. E. Mullen, W. K. Kaufmann, and A. Sancar, Coupling of human circadian and cell cycles by the timeless protein, Molecular and cellular biology, vol.25, issue.8, pp.3109-3116, 2005.

F. Valenzuela, J. Vera, C. Venegas, S. Munoz, S. Oyarce et al., , 2016.

S. Van-den-heiligenberg, P. Depres-brummer, H. Barbason, B. Claustrat, M. Reynes et al., The tumor promoting effect of constant light exposure on diethylnitrosamineinduced hepatocarcinogenesis in rats, International journal of endocrinology, vol.64, issue.26, pp.2523-2534, 1999.

G. Van-maele-fabry, V. Libotte, J. Willems, and D. Lison, Review and meta-analysis of risk estimates for prostate cancer in pesticide manufacturing workers, Cancer Causes & Control, vol.17, issue.4, pp.353-373, 2006.

G. Van-maele-fabry and J. Willems, Occupation related pesticide exposure and cancer of the prostate: a meta-analysis, Occupational and environmental medicine, vol.60, issue.9, pp.634-642, 2003.

G. Van-maele-fabry and J. Willems, Prostate cancer among pesticide applicators: a meta-analysis, International archives of occupational and environmental health, vol.77, issue.8, pp.559-570, 2004.

A. Villers, X. Rebillard, M. Soulie, J. Davin, P. Coloby et al., Progres en urologie: journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, vol.13, pp.209-214, 2003.

A. N. Viswanathan, S. E. Hankinson, and E. S. Schernhammer, Night shift work and the risk of endometrial cancer, Cancer Research, vol.67, issue.21, pp.10618-10622, 2007.

B. Wang, Z. M. Dai, Y. Zhao, X. J. Wang, H. F. Kang et al.,

. Dai, Current evidence on the relationship between two common polymorphisms in NPAS2 gene and cancer risk, Int J Clin Exp Med, vol.8, issue.5, pp.7176-7183, 2015.

F. Wang, Z. Hu, R. Yang, J. Tang, Y. Liu et al., A variant affecting miRNAs binding in the circadian gene Neuronal PAS domain protein 2 (NPAS2) is not associated with breast cancer risk, Breast cancer research and treatment, vol.127, issue.3, pp.769-775, 2011.

F. Wang, K. Yeung, W. Chan, C. Kwok, S. Leung et al., , 2013.

, A meta-analysis on dose-response relationship between night shift work and the risk of breast cancer, Annals of oncology, vol.24, issue.11, pp.2724-2732

D. K. Welsh, D. E. Logothetis, M. Meister, and S. M. Reppert, Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms, Neuron, vol.14, issue.4, pp.697-706, 1995.

A. S. Whittemore, A. H. Wu, L. N. Kolonel, E. M. John, R. P. Gallagher et al., Family history and prostate cancer risk in black, white, and Asian men in the United States and Canada, American journal of epidemiology, vol.141, issue.8, pp.732-740, 1995.

M. D. Wirth, J. B. Burch, J. R. Hébert, P. Kowtal, A. Mehrotra-kapoor et al., Case-Control Study of Breast Cancer in India: Role of PERIOD 3 Clock Gene Length Polymorphism and Chronotype, Cancer investigation, vol.32, issue.7, pp.321-329, 2014.

A. Wirtz and F. Nachreiner, The effects of extended working hours on health and social well-being-a comparative analysis of four independent samples, Chronobiology International, vol.27, issue.5, pp.1124-1134, 2010.

C. M. Woolf, An investigation of the familial aspects of carcinoma of the prostate, Cancer, vol.13, issue.4, pp.739-744, 1960.

R. Xiang, Y. Cui, Y. Wang, T. Xie, X. Yang et al., Circadian clock gene Per2 downregulation in nonsmall cell lung cancer is associated with tumour progression and metastasis, Oncol Rep, vol.40, issue.5, pp.3040-3048, 2018.

S. Xiang, S. B. Coffelt, L. Mao, L. Yuan, Q. Cheng et al., Period-2: a tumor suppressor gene in breast cancer, Journal of Circadian Rhythms, vol.6, issue.1, p.4, 2008.

X. Xue, F. Liu, Y. Han, P. Li, B. Yuan et al., Silencing NPAS2 promotes cell growth and invasion in DLD-1 cells and correlated with poor prognosis of colorectal cancer, Biochem Biophys Res Commun, vol.450, issue.2, pp.1058-1062, 2014.

C. Yi, L. Mu, I. A. De-la-longrais, O. Sochirca, R. Arisio et al.,

. Katsaro, The circadian gene NPAS2 is a novel prognostic biomarker for breast cancer, Breast Cancer Res Treat, vol.120, issue.3, pp.663-669, 2010.

K. Yu, Q. Li, A. W. Bergen, R. M. Pfeiffer, P. S. Rosenberg et al.,

. Chatterjee, Pathway analysis by adaptive combination of P-values, Genet Epidemiol, vol.33, issue.8, pp.700-709, 2009.

J. Zhao, T. Stockwell, A. Roemer, and T. Chikritzhs, Is alcohol consumption a risk factor for prostate cancer? A systematic review and meta-analysis, BMC cancer, vol.16, issue.1, p.845, 2016.

Y. Zhu, H. N. Brown, Y. Zhang, R. G. Stevens, and T. Zheng, Period3 structural variation: a circadian biomarker associated with breast cancer in young women, Cancer Epidemiology Biomarkers & Prevention, vol.14, issue.1, pp.268-270, 2005.

Y. Zhu, D. Leaderer, C. Guss, H. N. Brown, Y. Zhang et al., Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma, Int J Cancer, vol.120, issue.2, pp.432-435, 2007.

Y. Zhu, R. G. Stevens, A. E. Hoffman, L. M. Fitzgerald, E. M. Kwon et al., Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study, Cancer Res, vol.69, issue.24, pp.9315-9322, 2009.

Y. Zhu, R. G. Stevens, D. Leaderer, A. Hoffman, T. Holford et al., Non-synonymous polymorphisms in the circadian gene NPAS2 and breast cancer risk, Breast Cancer Res Treat, vol.107, issue.3, pp.421-425, 2008.

Y. Zhu, R. G. Stevens, D. Leaderer, A. Hoffman, T. Holford et al., Non-synonymous polymorphisms in the circadian gene NPAS2 and breast cancer risk, Breast cancer research and treatment, vol.107, issue.3, pp.421-425, 2008.

Y. Zhu and T. Zheng, Clock-cancer connection in non-Hodgkin's lymphoma, Med Hypotheses, vol.70, issue.4, pp.788-792, 2008.

S. Zienolddiny, A. Haugen, J. A. Lie, H. Kjuus, K. H. Anmarkrud et al., Analysis of polymorphisms in the circadian-related genes and breast cancer risk in Norwegian nurses working night shifts, Breast Cancer Res, vol.15, issue.4, p.53, 2013.

U. P. Zmrzljak and D. Rozman, Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters, Chemical research in toxicology, vol.25, issue.4, pp.811-824, 2012.

J. A. Horne and O. Ostberg, A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms, Int J Chronobiol, vol.4, pp.97-110, 1976.

J. Taillard, P. Philip, J. F. Chastang, and B. Bioulac, Validation of Horne and Ostberg morningness-eveningness questionnaire in a middle-aged population of french workers, J Biol Rhythms, vol.19, pp.76-86, 2004.

A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward et al., Global cancer statistics. CA: A Cancer Journal for Clinicians, vol.61, issue.2, pp.69-90, 2011.

A. Belot, P. Grosclaude, N. Bossard, E. Jougla, E. Benhamou et al., Cancer incidence and mortality in France over the period 1980-2005. Revue d'Épidémiologie et de Santé Publique, vol.56, pp.159-75, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00538673

A. W. Hsing and S. S. Devesa, Trends and patterns of prostate cancer: what do they suggest, Epidemiol Rev, vol.23, issue.3, p.13, 2001.

A. W. Hsing, L. C. Sakoda, and S. C. Chua, Obesity, metabolic syndrome, and prostate cancer. The American journal of clinical nutrition, vol.86, pp.843-57, 2007.

J. Lee, K. Demissie, S. Lu, and G. G. Rhoads, Cancer incidence among Korean-American immigrants in the United States and native Koreans in South Korea, Cancer Control, vol.14, issue.1, p.78, 2007.

C. Savvidis and M. Koutsilieris, Molecular Medicine, vol.18, issue.9, p.1, 2012.

C. Gronfier, Physiology of the endogenous circadian clock: From clock genes to clinical applications, Médecine du Sommeil, vol.6, issue.1, pp.3-11, 2009.

T. Roenneberg, Epidemiology of the human circadian clock, Sleep Medicine Reviews, vol.11, issue.6, pp.429-467, 2007.

N. Cermakian and D. Boivin, The regulation of central and peripheral circadian clocks in humans, Obesity Reviews, vol.10, issue.s2, pp.25-36, 2009.

L. Fu and C. C. Lee, The circadian clock: pacemaker and tumour suppressor, Nature Reviews Cancer, vol.3, issue.5, pp.350-61, 2003.

Q. Cao, S. Gery, A. Dashti, D. Yin, Y. Zhou et al., A role for the clock gene per1 in prostate cancer, Cancer Res, vol.69, pp.7619-7644, 2009.

Z. Kiss and P. M. Ghosh, WOMEN IN CANCER THEMATIC REVIEW: Circadian rhythmicity and the influence of 'clock'genes on prostate cancer, Endocrine-related cancer, vol.23, issue.11, pp.123-157, 2016.

Y. Zhu, R. G. Stevens, A. E. Hoffman, L. M. Fitzgerald, E. M. Kwon et al., Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study, Cancer Res, vol.69, issue.24, pp.9315-9337, 2009.

K. Straif, R. Baan, Y. Grosse, B. Secretan, E. Ghissassi et al., Carcinogenicity of shift-work, painting, and fire-fighting. The lancet oncology, vol.8, pp.1065-1071, 2007.

G. Costa, E. Haus, and R. Stevens, Shift work and cancer-considerations on rationale, mechanisms, and epidemiology. Scandinavian journal of work, environment & health, pp.163-79, 2010.

L. Fritschi, D. Glass, J. Heyworth, K. Aronson, J. Girschik et al., Hypotheses for mechanisms linking shiftwork and cancer. Medical hypotheses, vol.77, pp.430-436, 2011.

E. L. Haus and M. H. Smolensky, Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation, Sleep medicine reviews, vol.17, issue.4, pp.273-84, 2013.

E. Cordina-duverger, Y. Koudou, T. Truong, P. Arveux, P. Kerbrat et al., Night work and breast cancer risk defined by human epidermal growth factor receptor-2 (HER2) and hormone receptor status: A population-based case-control study in France, Chronobiology international, vol.2016, pp.1-5

F. Menegaux, T. Truong, A. Anger, E. Cordina-duverger, F. Lamkarkach et al., Night work and breast cancer: A population-based case-control study in France (the CECILE study), International Journal of Cancer, vol.132, issue.4, pp.924-955, 2013.

T. Truong, B. Liquet, F. Menegaux, S. Plancoulaine, P. Laurent-puig et al., Breast cancer risk, nightwork, and circadian clock gene polymorphisms, Endocrine-related cancer, vol.21, issue.4, pp.629-667, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01097160

S. Ijaz, J. Verbeek, A. Seidler, M. Lindbohm, A. Ojajarvi et al., Night-shift work and breast cancer-a systematic review and meta-analysis, Scand J Work Environ Health, vol.39, issue.5, pp.431-478, 2013.

Y. Jia, Y. Lu, K. Wu, Q. Lin, W. Shen et al., Does night work increase the risk of breast cancer? A systematic review and meta-analysis of epidemiological studies, Cancer epidemiology, vol.37, issue.3, pp.197-206, 2013.

B. B. Kamdar, A. I. Tergas, F. J. Mateen, N. H. Bhayani, and J. Oh, Night-shift work and risk of breast cancer: a systematic review and meta-analysis, Breast cancer research and treatment, vol.138, issue.1, pp.291-301, 2013.

F. Wang, K. Yeung, W. Chan, C. Kwok, S. Leung et al., A meta-analysis on doseresponse relationship between night shift work and the risk of breast cancer, Annals of oncology, vol.24, issue.11, pp.2724-2756, 2013.

R. C. Travis, A. Balkwill, G. K. Fensom, P. N. Appleby, G. K. Reeves et al., Night Shift Work and Breast Cancer Incidence: Three Prospective Studies and Meta-analysis of Published Studies, Journal of the National Cancer Institute, vol.108, issue.12, p.169, 2016.

L. G. Sigurdardottir, U. A. Valdimarsdottir, K. Fall, J. R. Rider, S. W. Lockley et al., Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies. Cancer epidemiology, biomarkers & prevention : a publication of the, American Society of Preventive Oncology, vol.21, issue.7, pp.1002-1013, 2012.

L. G. Sigurdardottir, U. A. Valdimarsdottir, K. Fall, J. R. Rider, S. W. Lockley et al., Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies, Cancer Epidemiology Biomarkers & Prevention, vol.21, issue.7, pp.1002-1013, 2012.

M. Conlon, N. Lightfoot, and N. Kreiger, Rotating shift work and risk of prostate cancer, Epidemiology, vol.18, issue.1, pp.182-185, 2007.

T. Kubo, I. Oyama, T. Nakamura, M. Kunimoto, K. Kadowaki et al., Industrybased retrospective cohort study of the risk of prostate cancer among rotating-shift workers

, Int J Urol, vol.18, issue.3, pp.206-217, 2011.

T. Kubo, K. Ozasa, K. Mikami, K. Wakai, Y. Fujino et al., Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study, American Journal of Epidemiology, vol.164, issue.6, pp.549-55, 2006.

J. Schwartzbaum, A. Ahlbom, and M. Feychting, Cohort study of cancer risk among male and female shift workers. Scand J Work Environ Health, vol.33, pp.336-379, 2007.

M. E. Parent, M. El-zein, M. C. Rousseau, J. Pintos, and J. Siemiatycki, Night work and the risk of cancer among men, Am J Epidemiol, vol.176, issue.9, pp.751-760, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-01007614

K. Papantoniou, G. Castano-vinyals, A. Espinosa, N. Aragones, B. Perez-gomez et al., Night shift work, chronotype and prostate cancer risk in the MCC-Spain case-control study, Int J Cancer, vol.137, issue.5, pp.1147-57, 2015.

S. M. Gapstur, W. R. Diver, V. L. Stevens, B. D. Carter, L. R. Teras et al., Work schedule, sleep duration, insomnia, and risk of fatal prostate cancer, Am J Prev Med, vol.46, issue.3, pp.26-33, 2014.

M. Yong, M. Blettner, K. Emrich, M. Nasterlack, C. Oberlinner et al., A retrospective cohort study of shift work and risk of incident cancer among German male chemical workers, Scand J Work Environ Health, vol.40, issue.5, pp.502-512, 2014.

B. A. Dickerman, S. C. Markt, M. Koskenvuo, C. Hublin, E. Pukkala et al., Sleep disruption, chronotype, shift work, and prostate cancer risk and mortality: a 30-year prospective cohort study of Finnish twins, Cancer causes & control : CCC, vol.27, issue.11, pp.1361-70, 2016.

D. Rao, H. Yu, Y. Bai, X. Zheng, and L. Xie, Does night-shift work increase the risk of prostate cancer? a systematic review and meta-analysis, Onco Targets Ther, vol.8, pp.2817-2843, 2015.

M. Kakizaki, K. Inoue, S. Kuriyama, T. Sone, K. Matsuda-ohmori et al., Sleep duration and the risk of prostate cancer: the Ohsaki Cohort Study, Br J Cancer, vol.99, issue.1, pp.176-184, 2008.

M. J. Thorpy, Classification of sleep disorders, Neurotherapeutics, vol.9, issue.4, pp.687-701, 2012.

L. G. Sigurdardottir, U. A. Valdimarsdottir, L. A. Mucci, K. Fall, J. R. Rider et al., Sleep disruption among older men and risk of prostate cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, American Society of Preventive Oncology, vol.22, issue.5, pp.872-881, 2013.

S. C. Markt, E. E. Flynn-evans, U. A. Valdimarsdottir, L. G. Sigurdardottir, R. M. Tamimi et al., Sleep Duration and Disruption and Prostate Cancer Risk: a 23-Year Prospective Study, Cancer Epidemiology Biomarkers & Prevention, vol.25, issue.2, pp.302-310, 2015.

S. C. Markt, A. Grotta, O. Nyren, H. Adami, L. A. Mucci et al., Insufficient sleep and risk of prostate cancer in a large Swedish cohort, Sleep, vol.38, issue.9, p.1405, 2015.

L. W. Chu, Y. Zhu, K. Yu, T. Zheng, H. Yu et al., Variants in circadian genes and prostate cancer risk: a population-based study in China, Prostate Cancer Prostatic Dis, vol.11, issue.4, pp.342-350, 2008.

S. C. Markt, U. A. Valdimarsdottir, I. M. Shui, L. G. Sigurdardottir, J. R. Rider et al., Circadian clock genes and risk of fatal prostate cancer, Cancer causes & control : CCC, vol.26, issue.1, pp.25-33, 2015.

S. H. Downs and N. Black, The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions, J Epidemiol Community Health, vol.52, issue.6, pp.377-84, 1998.

B. Peplonska, W. Burdelak, A. Bukowska, J. Krysicka, and K. Konieczko, Night shift work characteristics and occupational co-exposures in industrial plants in Lodz, Poland. International journal of occupational medicine and environmental health, vol.26, pp.522-556, 2013.

L. G. Sigurdardottir, S. C. Markt, J. R. Rider, S. Haneuse, K. Fall et al., Urinary melatonin levels, sleep disruption, and risk of prostate cancer in elderly men, European urology, vol.67, issue.2, pp.191-195, 2015.

A. H. Wu, R. Wang, W. P. Koh, F. Z. Stanczyk, H. P. Lee et al., Sleep duration, melatonin and breast cancer among Chinese women in Singapore, Carcinogenesis, vol.29, issue.6, pp.1244-1252, 2008.

E. S. Schernhammer and K. Schulmeister, Melatonin and cancer risk: does light at night compromise physiologic cancer protection by lowering serum melatonin levels?, Br J Cancer, vol.90, issue.5, pp.941-944, 2004.

I. Kloog, A. Haim, R. G. Stevens, and B. A. Portnov, Global co-distribution of light at night (LAN) and cancers of prostate, colon, and lung in men, Chronobiol Int, vol.26, issue.1, pp.108-133, 2009.

S. E. Bauer, S. E. Wagner, J. Burch, R. Bayakly, and J. E. Vena, A case-referent study: light at night and breast cancer risk in Georgia, International journal of health geographics, vol.12, p.23, 2013.

S. Hurley, D. Goldberg, D. Nelson, A. Hertz, P. L. Horn-ross et al., Light at night and breast cancer risk among California teachers, Epidemiology, vol.25, issue.5, pp.697-706, 2014.

I. Kloog, R. G. Stevens, A. Haim, and B. A. Portnov, Nighttime light level co-distributes with breast cancer incidence worldwide, Cancer causes & control : CCC, vol.21, issue.12, pp.2059-68, 2010.

Q. Li, T. Zheng, T. R. Holford, P. Boyle, Y. Zhang et al., Light at night and breast cancer risk: results from a population-based case-control study in Connecticut, USA. Cancer causes & control : CCC, vol.21, issue.12, pp.2281-2286, 2010.
URL : https://hal.archives-ouvertes.fr/hal-01260413

B. A. Portnov, R. G. Stevens, H. Samociuk, D. Wakefield, and D. I. Gregorio, Light at night and breast cancer incidence in Connecticut: An ecological study of age group effects. The Science of the total environment, vol.572, pp.1020-1024, 2016.

N. Rybnikova, A. Haim, and B. A. Portnov, Artificial Light at Night (ALAN) and breast cancer incidence worldwide: A revisit of earlier findings with analysis of current trends, Chronobiol Int, vol.32, issue.6, pp.757-73, 2015.

R. G. Stevens, Light-at-night, circadian disruption and breast cancer: assessment of existing evidence, Int J Epidemiol, vol.38, issue.4, pp.963-70, 2009.

L. W. Chu, Y. Zhu, K. Yu, T. Zheng, A. P. Chokkalingam et al., Correlation between circadian gene variants and serum levels of sex steroids and insulin-like growth factor-I. Cancer epidemiology, biomarkers & prevention : a publication of the, American Society of Preventive Oncology, vol.17, issue.11, pp.3268-73, 2008.

S. Rabstein, V. Harth, C. Justenhoven, B. Pesch, S. Plottner et al., Polymorphisms in circadian genes, night work and breast cancer: results from the GENICA study, Chronobiol Int, vol.31, issue.10, pp.1115-1137, 2014.

R. G. Stevens, J. Hansen, G. Costa, E. Haus, T. Kauppinen et al., Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report, Occup Environ Med, vol.68, issue.2, pp.154-62, 2011.

T. Narusyte, P. Svedberg, G. Kecklund, and K. Alexanderson, Adjusted for age, family history of Prostate Cancer, race, education level / 2 95% CI: 95% confidence interval REFERENCES Akerstedt, BMJ Open, vol.7, p.15751, 2017.

T. Behrens, S. Rabstein, K. Wichert, R. Erbel, L. Eisele et al., Shift work and the incidence of prostate cancer: a 10-year follow-up of a German population-based cohort study, Scandinavian journal of work, vol.43, pp.560-68, 2017.

M. Conlon, N. Lightfoot, and N. Kreiger, Rotating shift work and risk of prostate cancer, Epidemiology, vol.18, pp.182-185, 2007.

E. Cordina-duverger, F. Menegaux, A. Popa, S. Rabstein, V. Harth et al.,

D. C. Fritschi, J. S. Glass, T. C. Heyworth, G. Erren, K. Castano-vinyals et al., Night shift work and breast cancer: a pooled analysis of population-based casecontrol studies with complete work history, Eur J Epidemiol, 2018.

G. Costa, E. Haus, and R. Stevens, Shift work and cancerconsiderations on rationale, mechanisms, and epidemiology, Scandinavian journal of work, pp.163-79, 2010.

. Dares, Le travail de nuit en 2012.', Dares Analyses -Publication de la Direction de l'Animation de la Recherche, des Etudes et des Statistiques, vol.62, pp.1-8, 2014.

B. A. Dickerman, S. C. Markt, M. Koskenvuo, C. Hublin, E. Pukkala et al.,

. Kaprio, Sleep disruption, chronotype, shift work, and prostate cancer risk and mortality: a 30-year prospective cohort study of Finnish twins, Cancer Causes Control, vol.27, pp.1361-70, 2016.

T. C. Erren and P. Morfeld, Shift work and cancer research: a thought experiment into a potential chronobiological fallacy of past and perspectives for future epidemiological studies, Neuro Endocrinol Lett, vol.34, pp.282-288, 2013.

L. Fritschi, . Glass, . Heyworth, J. Aronson, . Girschik et al., Hypotheses for mechanisms linking shiftwork and cancer, Medical hypotheses, vol.77, pp.430-466, 2011.

S. M. Gapstur, W. R. Diver, V. L. Stevens, B. D. Carter, L. R. Teras et al., Work schedule, sleep duration, insomnia, and risk of fatal prostate cancer, Am J Prev Med, vol.46, pp.26-33, 2014.

. Globocan, Prostate cancer : estimated incidence, mortality and prevalence worldwide in, 2012.

C. Gronfier, B. Barthe, D. Bérard, L. Beugnet, F. Chappert et al., Évaluation des risques sanitaires liés au travail de nuit, p.408, 2016.

P. Grosclaude, A. Belot, L. Marliac, L. Remontet, N. Leone et al., Prostate cancer incidence and mortality trends in France from, Prog Urol, vol.25, pp.536-578, 1980.
URL : https://hal.archives-ouvertes.fr/hal-02044767

A. Grundy, J. M. Schuetz, A. S. Lai, R. Spinelli, and K. J. ,

. Aronson, Shift work, circadian gene variants and risk of breast cancer, Cancer epidemiology, vol.37, pp.606-618, 2013.

M. Harma, A. Koskinen, A. Ropponen, S. Puttonen, K. Karhula et al., Validity of self-reported exposure to shift work, Occup Environ Med, vol.74, pp.228-258, 2017.

E. L. Haus and M. H. Smolensky, Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation, Sleep medicine reviews, vol.17, pp.273-84, 2013.

J. A. Horne and O. Ostberg, A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms, Int J Chronobiol, vol.4, pp.97-110, 1976.

A. W. Hsing and S. S. Devesa, Trends and patterns of prostate cancer: what do they suggest, Epidemiol. Rev, vol.23, p.13, 2001.

A. W. Hsing, C. Lori, . Sakoda, C. Streamson, and . Chua, Obesity, metabolic syndrome, and prostate cancer, The American journal of clinical nutrition, vol.86, pp.843-57, 2007.

Y. Hu, A. Shmygelska, D. Tran, N. Eriksson, J. Y. Tung et al., GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person, Nat Commun, vol.7, p.10448, 2016.

T. Kubo, I. Oyama, T. Nakamura, M. Kunimoto, K. Kadowaki et al., Industry-based retrospective cohort study of the risk of prostate cancer among rotating-shift workers, Int J Urol, vol.18, pp.206-217, 2011.

T. Kubo, K. Ozasa, K. Mikami, K. Wakai, Y. Fujino et al.,

K. Hayashi, M. Suzuki, M. Mori, F. Washio, Y. Sakauchi et al.,

. Tamakoshi, Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study, Am J Epidemiol, vol.164, pp.549-55, 2006.

J. Lee, K. Demissie, G. Lu, and . Rhoads, Cancer incidence among Korean-American immigrants in the United States and native Koreans in South Korea, Cancer Control, vol.14, p.78, 2007.

J. A. Lie, H. Kjuus, S. Zienolddiny, A. Haugen, R. G. Stevens et al., Night work and breast cancer risk among Norwegian nurses: assessment by different exposure metrics, Am J Epidemiol, vol.173, pp.1272-1281, 2011.

L. Mao, R. T. Dauchy, D. E. Blask, L. M. Slakey, S. Xiang et al., Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3beta, Mol Endocrinol, vol.26, pp.1808-1828, 2012.

F. Menegaux, A. Anger, H. Randrianasolo, C. Mulot, P. Laurent-puig et al., Epidemiological study of prostate cancer (EPICAP): a population-based case-control study in France, BMC Cancer, vol.14, p.106, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-00952941

K. Papantoniou, G. Castano-vinyals, A. Espinosa, N. Aragones, B. Perez-gomez et al.,

M. Pollan and . Kogevinas, Night shift work, chronotype and prostate cancer risk in the MCC-Spain case-control study, Int J Cancer, vol.137, pp.1147-57, 2015.

. Parent-thirion, E. F. Agnès, J. Macias, G. Hurley, and . Vermeylen, Fourth European Working Conditions Survey, 139. European Foundation for the Improvement of Living and Working Conditions, 2007.

M. E. Parent, M. El-zein, M. C. Rousseau, J. Pintos, and J. Siemiatycki, Night work and the risk of cancer among men, Am J Epidemiol, vol.176, pp.751-760, 2012.
URL : https://hal.archives-ouvertes.fr/pasteur-01007614

D. Rao, H. Yu, Y. Bai, X. Zheng, and L. Xie, Does night-shift work increase the risk of prostate cancer? a systematic review and meta-analysis, Onco Targets Ther, vol.8, pp.2817-2843, 2015.

I. B. Saksvik, B. Bjorvatn, H. Hetland, G. M. Sandal, and S. Pallesen, Individual differences in tolerance to shift work--a systematic review, Sleep Med Rev, vol.15, pp.221-256, 2011.

J. Schwartzbaum, A. Ahlbom, and M. Feychting, Cohort study of cancer risk among male and female shift workers, Scand J Work Environ Health, vol.33, pp.336-379, 2007.

L. G. Sigurdardottir, U. A. Valdimarsdottir, K. Fall, J. R. Rider, S. W. Lockley et al., Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies, Cancer Epidemiol Biomarkers Prev, vol.21, pp.1002-1013, 2012.

R. G. Stevens, J. Hansen, G. Costa, E. Haus, T. Kauppinen et al.,

T. Vermeulen, V. Zheng, K. Cogliano, and . Straif, Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report, Occup Environ Med, vol.68, pp.154-62, 2011.

K. Straif, R. Baan, Y. Grosse, B. Secretan, F. E. Ghissassi et al., Lamia Benbrahim-Tallaa, Vincent Cogliano, and WHO International Agency for Research on Cancer Monograph Working Group, The lancet oncology, vol.8, pp.1065-66, 2007.

J. Taillard, P. Philip, J. Chastang, and B. Bioulac, Validation of Horne and Ostberg morningness-eveningness questionnaire in a middleaged population of French workers, Journal of biological rhythms, vol.19, pp.76-86, 2004.

R. Travail, . Française-ministère, and . Du, Le travail de nuit, 2015.

T. Truong, B. Liquet, F. Menegaux, S. Plancoulaine, P. Laurent-puig et al., Breast cancer risk, nightwork, and circadian clock gene polymorphisms, Endocr Relat Cancer, vol.21, pp.629-667, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01097160

. Wendeu-foyet, G. Méyomo, and F. Menegaux, Circadian Disruption and Prostate Cancer Risk: An Updated Review of Epidemiological Evidences, Cancer Epidemiology and Prevention Biomarkers, 2016.

M. Yong, M. Blettner, K. Emrich, M. Nasterlack, C. Oberlinner et al., A retrospective cohort study of shift work and risk of incident cancer among German male chemical workers, Scand J Work Environ Health, vol.40, pp.502-512, 2014.

C. Bernard, O. Boyer, M. Campo, S. Margaroli, L. N. 'diaye et al., We also would like to thank Christian Prad and Nadine Soller for help with patient medical data collection within the Hérault Cancer Registry (Registre des tumeurs de l'Hérault, Finally, we are grateful to the EPICAP study Group: Urologists: Drs Didier Ayuso

M. Locci, Etienne Cuénant

F. ). Sète, N. Drianno, B. Marc, and P. Soares, Clinique

, Samer Abdel Hamid

T. Murez, G. Poinas, L. Cabaniols, M. Robert, and R. Thuret,

R. Granier, . Borges-reis, and . Badsi,

F. Simony, P. Bibeau, and . Baldet,

H. Universitaire and . Lapeyronie,

, and Labosud laboratories: Drs François et Pascal Dumas

, Fondation ARC and Ligue nationale contre le cancer. The EPICAP study was funded: by Ligue nationale contre le cancer Ligue contre le cancer du Val de Marne, Fondation de France, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES). The first author, Méyomo G. Wendeu-Foyet, is funded by a 3-years doctoral allowance of the Doctoral School of Public Health (EDSP), FUNDING The EPICAP-chrono project was funded: by Institut National du Cancer

, Circadian genes and risk of prostate cancer: findings from the EPICAP study

, Géraldine Cancel-Tassin, vol.4

*. Co,

, Hérault Cancer Registry, EA 2415, ICM

, Clinique Beau Soleil

H. Cerepp and . Tenon,

S. Université, A. Oncotype-uro, and H. Tenon,

L. Imagenome,

U. Paris-descartes and I. Epigenetec, These results are mainly driven by two genes from the core-genes pathway, which were significantly associated to prostate cancer risk: NPAS2 (FDR P=0.06) and, p.1

C. Bernard, O. Boyer, M. Campo, S. Margaroli, and L. N. Diaye, Sabine Perrier-Bonnet)

, We also would like to thank Christian Prad and Nadine Soller for help with patient medical data collection within the Hérault Cancer Registry (Registre des tumeurs de l'Hérault, and Cécile Gaffory and Valérie Ondet for technical assistance (CeRePP)

, Finally, we are grateful to the EPICAP study Group: Urologists: Drs Didier Ayuso

M. Locci, Etienne Cuénant

F. ). Sète, N. Drianno, B. Marc, and P. Soares, Clinique

, Samer Abdel Hamid

T. Murez, G. Poinas, L. Cabaniols, M. Robert, and R. Thuret,

R. Granier, . Borges-reis, and . Badsi,

F. Simony, P. Bibeau, and . Baldet,

H. Universitaire and . Lapeyronie,

, and Labosud laboratories: Drs François et Pascal Dumas

L. Fu and C. C. Lee, The circadian clock: pacemaker and tumour suppressor, Nature reviews Cancer, vol.3, issue.5, pp.350-61, 2003.

C. Gronfier, Physiology of the endogenous circadian clock: From clock genes to clinical applications, Médecine du Sommeil, vol.6, issue.1, pp.3-11, 2009.

Y. Zhu, R. G. Stevens, and A. E. Hoffman, Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study, Cancer Res, vol.69, issue.24, pp.9315-9337, 2009.

T. Roenneberg, T. Kuehnle, and M. Juda, Epidemiology of the human circadian clock, Sleep Med Rev, vol.11, issue.6, pp.429-467, 2007.

R. G. Foster and L. Kreitzman, The rhythms of life: what your body clock means to you! Experimental physiology, vol.99, pp.599-606, 2014.

E. W. Lamont, F. O. James, and D. B. Boivin, From circadian clock gene expression to pathologies, Sleep Med, vol.8, issue.6, pp.547-56, 2007.

T. Merbitz-zahradnik and E. Wolf, How is the inner circadian clock controlled by interactive clock proteins?: Structural analysis of clock proteins elucidates their physiological role

, FEBS Lett, vol.589, issue.14, pp.1516-1545, 2015.

H. Ukai and H. R. Ueda, Systems biology of mammalian circadian clocks, Annu Rev Physiol, vol.72, pp.579-603, 2010.

J. S. Takahashi, Transcriptional architecture of the mammalian circadian clock, Nat Rev Genet, vol.18, issue.3, pp.164-79, 2017.

C. H. Ko and J. S. Takahashi, Molecular components of the mammalian circadian clock, Human molecular genetics, vol.15, issue.suppl_2, pp.271-77, 2006.

J. P. Pett, A. Korencic, and F. Wesener, Feedback Loops of the Mammalian Circadian Clock Constitute Repressilator, PLoS computational biology, vol.12, issue.12, p.1005266, 2016.

L. Ercolani, A. Ferrari, D. Mei, and C. , Circadian clock: Time for novel anticancer strategies, Pharmacol Res, vol.100, pp.288-95, 2015.

F. C. Kelleher, A. Rao, and A. Maguire, Circadian molecular clocks and cancer, Cancer letters, vol.342, issue.1, pp.9-18, 2014.

R. V. Kondratov, V. Y. Gorbacheva, and M. P. Antoch, The role of mammalian circadian proteins in normal physiology and genotoxic stress responses, Current topics in developmental biology, vol.78, pp.173-216, 2007.

G. M. Monsees, P. Kraft, and S. E. Hankinson, Circadian genes and breast cancer susceptibility in rotating shift workers, Int J Cancer, vol.131, issue.11, pp.2547-52, 2012.

L. Fu and C. C. Lee, The circadian clock: pacemaker and tumour suppressor, Nature Reviews Cancer, vol.3, issue.5, pp.350-61, 2003.

K. Straif, R. Baan, and Y. Grosse, Carcinogenicity of shift-work, painting, and fire-fighting, The lancet oncology, vol.8, issue.12, pp.1065-66, 2007.

L. Fritschi, D. C. Glass, and J. S. Heyworth, Hypotheses for mechanisms linking shiftwork and cancer, Med Hypotheses, vol.77, issue.3, pp.430-436, 2011.

C. Benna, C. Helfrich-forster, and S. Rajendran, Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis, Oncotarget, vol.8, issue.14, pp.23978-95, 2017.

S. Mocellin, S. Tropea, and C. Benna, Circadian pathway genetic variation and cancer risk: evidence from genome-wide association studies, BMC medicine, vol.16, issue.1, p.20, 2018.

A. Grundy, J. M. Schuetz, and A. S. Lai, Shift work, circadian gene variants and risk of breast cancer, Cancer epidemiology, vol.37, issue.5, pp.606-618, 2013.

S. Rabstein, V. Harth, and C. Justenhoven, Polymorphisms in circadian genes, night work and breast cancer: results from the GENICA study, Chronobiol Int, vol.31, issue.10, pp.1115-1137, 2014.

T. Truong, B. Liquet, and F. Menegaux, Breast cancer risk, nightwork, and circadian clock gene polymorphisms, Endocr Relat Cancer, vol.21, issue.4, pp.629-667, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01097160

S. Zienolddiny, A. Haugen, and J. A. Lie, Analysis of polymorphisms in the circadian-related genes and breast cancer risk in Norwegian nurses working night shifts, Breast cancer research : BCR, vol.15, issue.4, p.53, 2013.

L. Chu, Y. Zhu, and K. Yu, Variants in circadian genes and prostate cancer risk: a population-based study in China, Prostate cancer and prostatic diseases, vol.11, issue.4, pp.342-390, 2007.

L. W. Chu, C. Till, and B. Yang, Circadian genes and risk of prostate cancer in the prostate cancer prevention trial, Molecular carcinogenesis, vol.57, issue.3, pp.462-66, 2018.

F. Gu, H. Zhang, and P. L. Hyland, Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia, Int J Cancer, vol.141, issue.9, pp.1794-802, 2017.

S. C. Markt, U. A. Valdimarsdottir, and I. M. Shui, Circadian clock genes and risk of fatal prostate cancer, Cancer causes & control : CCC, vol.26, issue.1, pp.25-33, 2015.

F. Menegaux, A. Anger, and H. Randrianasolo, Epidemiological study of prostate cancer (EPICAP): a population-based case-control study in France, BMC Cancer, vol.14, p.106, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-00952941

C. I. Amos, J. Dennis, and Z. Wang, The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, American Society of Preventive Oncology, vol.26, issue.1, pp.126-161, 2017.

Y. Li, J. Byun, and G. Cai, FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data, BMC bioinformatics, vol.17, p.122, 2016.

R. J. Hung, C. M. Ulrich, and E. L. Goode, Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer, J Natl Cancer Inst, vol.107, issue.11, 2015.

K. Yu, Q. Li, and A. W. Bergen, Pathway analysis by adaptive combination of P-values, Genetic epidemiology, vol.33, issue.8, pp.700-709, 2009.

Y. Benjamini and Y. Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the royal statistical society Series B (Methodological), vol.1995, pp.289-300

S. Rana and S. Mahmood, Circadian rhythm and its role in malignancy, Journal of circadian rhythms, vol.8, p.3, 2010.

A. E. Hoffman, T. Zheng, and Y. Ba, The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response, Molecular cancer research : MCR, vol.6, issue.9, pp.1461-1469, 2008.

X. Xue, F. Liu, and Y. Han, Silencing NPAS2 promotes cell growth and invasion in DLD-1 cells and correlated with poor prognosis of colorectal cancer, Biochemical and biophysical research communications, vol.450, issue.2, pp.1058-62, 2014.

N. K. Mukhopadhyay, A. S. Ferdinand, and L. Mukhopadhyay, Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor, Experimental cell research, vol.312, issue.19, pp.3782-95, 2006.

G. Jenster, The role of the androgen receptor in the development and progression of prostate cancer, Semin Oncol, vol.26, issue.4, pp.407-428, 1999.

S. T. Chen, K. B. Choo, and M. F. Hou, Deregulated expression of the PER1, PER2 and PER3 genes in breast cancers, Carcinogenesis, vol.26, issue.7, pp.1241-1247, 2005.

S. Fonnes, A. M. Donatsky, and I. Gogenur, Expression of core clock genes in colorectal tumour cells compared with normal mucosa: a systematic review of clinical trials, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, vol.17, issue.4, pp.290-297, 2015.

W. Krugluger, A. Brandstaetter, and E. Kallay, Regulation of genes of the circadian clock in human colon cancer: reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors, Cancer Res, vol.67, issue.16, pp.7917-7939, 2007.

Q. Cao, S. Gery, and A. Dashti, A role for the clock gene per1 in prostate cancer, Cancer Res, vol.69, pp.7619-7644, 2009.

S. Gery, N. Komatsu, and L. Baldjyan, The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells, Molecular cell, vol.22, issue.3, pp.375-82, 2006.

J. Du and R. Xu, RORalpha, a potential tumor suppressor and therapeutic target of breast cancer

, Int J Mol Sci, vol.13, issue.12, pp.15755-66, 2012.

J. Li, K. Humphreys, and T. Heikkinen, A combined analysis of genome-wide association studies in breast cancer, Breast Cancer Res Treat, vol.126, issue.3, pp.717-744, 2011.

J. A. Lie, H. Kjuus, and S. Zienolddiny, Night work and breast cancer risk among Norwegian nurses: assessment by different exposure metrics, Am J Epidemiol, vol.173, issue.11, pp.1272-1281, 2011.

C. Yi, L. Mu, and I. A. De-la-longrais, The circadian gene NPAS2 is a novel prognostic biomarker for breast cancer, Breast Cancer Res Treat, vol.120, issue.3, pp.663-672, 2010.

Y. Zhu, D. Leaderer, and C. Guss, Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma, Int J Cancer, vol.120, issue.2, pp.432-437, 2007.

Y. Zhu, R. G. Stevens, and D. Leaderer, Non-synonymous polymorphisms in the circadian gene NPAS2 and breast cancer risk, Breast Cancer Res Treat, vol.107, issue.3, pp.421-426, 2008.