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Towards a combined statistical shape and musculoskeletal modeling framework for pediatric shoulder joint

Abstract : Obstetrician Brachial Plexus Palsy (OBPP) is a common birth injury in children leading to shoulder joint deformity and abnormal function. While the management of OBPP disorder focuses on restoring the shoulder joint function, the underlying pathomechanics is not clearly understood yet. Computational models are effective to provide such insights, however, there is no pediatric shoulder joint model to understand the OBPP disorder. Thus, the global aim of this research work was to build a computational framework combining the advances in statistical shape modeling (SSM) and multi-body musculoskeletal modeling (MSKM) domains. Due to a lack of sufficient data in the pediatric cohort, I first developed the framework for adult shoulder joint. For this, I illustrated the accuracy of SSM in predicting 1) missing part of the scapula, and 2) muscle insertion regions on scapula and humerus bones.This method was then integrated with adult shoulder MSKMs to show the differences between generic and subject specific constructs. For the second aim of this thesis, I developed a pediatric MSKM of the shoulder joint complex using OpenSim software. Pediatric MSKM represented scapulothoracic, sternoclavicular, acromioclavicular, and glenohumeral joints with 13 degrees of freedom, and actuated by 52 musculotendon actuators representing 14 shoulder muscles. Using inverse kinematics and inverse dynamics approaches, the model was used to determine the differences in joint kinematics, and joint dynamics between healthy and unhealthy side of a single OBPP subject. Future work is focused on completing the framework on pediatric population and understanding the pathomechanics of OBPP.
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Submitted on : Monday, December 16, 2019 - 4:09:08 PM
Last modification on : Friday, September 25, 2020 - 3:35:54 AM


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  • HAL Id : tel-02414431, version 1


Asma Salhi. Towards a combined statistical shape and musculoskeletal modeling framework for pediatric shoulder joint. Medical Imaging. Ecole nationale supérieure Mines-Télécom Atlantique, 2019. English. ⟨NNT : 2019IMTA0137⟩. ⟨tel-02414431⟩



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