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Caractérisation structurale et activités biologiques des polysaccharides d'Astragalus gombo bunge

Abstract : Astragalus gombo Bunge (Fabaceae) is a terrestrial plant occuring in the East Septentrional Sahara (Ouargla, Algeria). It is commonly used as fodder or in traditional medicine by local populations. Despite numerous publications focusing on polysaccharidic contents of Astragalus species and the designation of their putative or proved biological activities, no study has examined those of A. gombo. The objective of this thesis was firstly to investigate several organs of this plant for their polysaccharide contents. In a second step, the biological and rheological properties of these biopolymers have been studied to identify ways of adding value. Results led to the identification of pectic compounds and hemicelluloses in the rods of Astragalus gombo whereas a galactomannan was detected in its seeds. This galactomannan was a high molecular weight macromolecule composed of a β-(1→4)-D-mannan skeleton ramified by residues of D-galactopyranoses. The M/G ratio was of 1.7. The characterization of its rheological behavior was typic of that of a rheofluidifiant fluid with viscoelastic properties. The study of its biological properties showed its potential as prebiotic and antioxidant agent.
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Toufik Chouana. Caractérisation structurale et activités biologiques des polysaccharides d'Astragalus gombo bunge. Biologie végétale. Université Clermont Auvergne, 2017. Français. ⟨NNT : 2017CLFAC112⟩. ⟨tel-02414068⟩

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