G. F. Abd-ellatef, O. M. Ahmed, E. S. Abdel-reheim, and A. Z. Abdel-hamid, Ulva lactuca polysaccharides prevent Wistar rat breast carcinogenesis through the augmentation of apoptosis, enhancement of antioxidant defense system, and suppression of inflammation, Breast Cancer, vol.9, pp.67-83, 2017.

T. J. Ahern, S. Katoh, and E. Sada, Arachidonic acid production by the red alga Porphyridium cruentum, Biotechnol. Bioeng, vol.25, pp.1050-1070, 1983.

K. Aizawa and S. Miyachi, Carbonic anhydrase and CO2 concentrating mechanisms in microalgae and cyanobacteria, FEMS Microbiol. Lett, vol.39, pp.215-233, 1986.

S. Akimoto, M. Yokono, F. Hamada, A. Teshigahara, S. Aikawa et al., Adaptation of light-harvesting systems of Arthrospira platensis to light conditions, probed by time-resolved fluorescence spectroscopy, Biochim. Biophys. Acta. Bioenerg, vol.1817, pp.1483-1489, 2012.

R. Amorim, J. Rodrigues, M. Holanda, A. Quinderé, R. Paula et al., Antimicrobial effect of a crude sulfated polysaccharide from the red seaweed Gracilaria ornate, Braz. Arch. Biol. Technol, vol.55, pp.171-181, 2012.

G. Amoroso, D. Sultemeyer, C. Thyssen, and H. P. Fock, Uptake of HCO3 ? and CO2 in cells and chloroplasts from the microalgae Chlamydomonas reinhardtii and Dunaliella tertiolecta, Plant Physiol, vol.116, pp.193-201, 1998.

S. Arad, M. Huliheil, and J. Tal, Antiviral agents, WO1997000689A1, 1995.

S. Arad, Y. Lerental, and O. Dubinsky, Effect of Nitrate and Sulfate Starvation on Polysaccharide Formation in Rhodella reticulate, Bioresour. Technol, vol.42, pp.141-148, 1992.

S. Arad, L. Rapoport, A. Moshkovich, D. Van-moppes, M. Karpasas et al., Superior biolubricant from a species of red microalga, Langmuir, vol.22, pp.7313-7317, 2006.

S. Arad and Y. Weinstein, Novel lubricants from red microalgae: interplay between genes and products, Biomed, vol.1, pp.32-37, 2003.

S. M. Arad, O. D. Friedman, and A. Rotem, Effect of Nitrogen on Polysaccharide Production in a Porphyridium sp, Appl. Environ. Microbiol, vol.54, pp.2411-2414, 1988.

S. M. Arad and O. Levy-ontman, Red microalgal cell-wall polysaccharides: biotechnological aspects, Curr. Opin. Biotech, vol.21, pp.358-364, 2010.

S. M. Arad and A. Yaron, Natural pigments from red microalgae for use in foods and cosmetics, Trends Food Sci. Tech, vol.3, pp.92-97, 1992.

C. Ariyachet, N. V. Solis, Y. Liu, N. V. Prasadarao, S. G. Filler et al., SR-Like RNAbinding proteinSlr1 affects Candida albicans filamentation and virulence, Infect. Immun, vol.81, pp.267-1276, 2013.

S. Azaman, N. Nagao, F. Yusoff, S. Tan, and S. Yeap, A comparison of the morphological and biochemical characteristics of Chlorella sorokiniana and Chlorella zofingiensis cultured under photoautotrophic and mixotrophic conditions, Peer J, vol.5, 2017.

G. Barbier, C. Oesterhelt, M. D. Larson, R. G. Halgren, C. Wilkerson et al., Comparative genomics of two closely related unicellular thermoacidophilic red algae, Galdieria sulphuraria and Cyanidioschyzon merolae, reveals the molecular basis of the metabolic flexibility of Galdieria sulphuraria and significant differences in carbohydrate metabolism of both algae, Plant Physiol, vol.137, pp.460-474, 2005.

K. C. Bayona, S. M. Gallón, A. L. Estrada, J. C. Rios, L. A. Garces et al., Activity of Sulfated Polysaccharides from Microalga Porphyridiumcruentum over

, Degenerative Mechanisms of the Skin, Int. J. Sci. Adv. Technol, vol.2, pp.85-92, 2012.

E. W. Becker, Micro-algae as a source of protein, Biotechnol. Adv, vol.25, pp.207-210, 2007.

E. W. Becker, Microalgae: biotechnology and microbiology, 1994.

J. Benavides and M. Rito-palomares, Simplified two-stage method to B-phycoerythrin recovery from Porphyridium cruentum, J. Chrom. B, vol.844, pp.39-44, 2006.

R. Bermejo, F. G. Acién, M. J. Ibáñez, J. M. Fernández, E. Molina et al., Preparative purification of B-phycoerythrin from the microalga Porphyridium cruentum by expanded-bed adsorption chromatography, J. Chromatogr. B: Anal. Technol. Biomed. Life Sci, vol.790, pp.317-325, 2003.

R. Bermejo, J. M. Alvarez-pez, A. Fernandez, and E. M. Grima, Recovery of pure B-phycoerythrin from the microalga Porphyridium cruentum, J. Biotechnol, vol.93, pp.73-85, 2002.

R. Bermejo, E. Ruiz, and F. G. Acien, Recovery of B-phycoerythrin using expanded bed adsorption chromatography: Scale-up of the process, Enzyme Microb. Technol, vol.40, pp.927-933, 2007.

R. Bermejo, E. M. Talavera, and J. M. Alvarez-pez, Chromatographic purification and characterization of B-phycoerythrin from Porphyridium cruentum. Semi preparative HPLC separation and characterization of its subunits, J. Chromatogr, vol.917, pp.135-145, 2001.

R. Bermejo, D. J. Tobaruela, E. M. Talavera, A. Orte, and J. M. Alvarez-pez, Fluorescent behavior of B-phycoerythrin in microemulsions of aerosol OT/water/isooctane, J. Colloid. Interface Sci, vol.263, pp.616-640, 2003.

D. Bhattacharya, D. C. Price, C. X. Chan, H. Qiu, N. Rose et al.,

B. Henrissat, P. M. Coutinho, A. Krishnan, S. Zauner, S. Morath et al.,

M. M. Perrineau and H. S. Yoon, Genome of the red alga Porphyridium purpureum, Nat. Commun, vol.4, p.1941, 2013.

E. G. Bligh and W. J. Dyer, A rapid method of total lipid extraction and purification, Can. J. biochem. physiol, vol.37, pp.911-917, 1959.

R. C. Bollman and G. G. Robinson, The kinetics of organic acid uptake by three Chlorophyta in axenic culture, J. Phycol, vol.13, pp.1-5, 1977.

E. Borghi, G. Morace, F. Borgo, R. Rajendran, L. Sherry et al., New strategic insights into managing fungal biofilms, Front. Microbial, vol.6, p.1077, 2015.

M. A. Borowitzka, Microalgae as sources of essential fatty acids, Aust. J. Biotechnol, vol.1, pp.58-62, 1988.

N. Boyle and J. Morgan, Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii, BMC Syst. Biol, vol.3, p.4, 2009.

N. R. Boyle, N. Sengupta, and J. A. Morgan, Metabolic flux analysis of heterotrophic growth in Chlamydomonas reinhardtii, Plos one, vol.12, pp.1-23, 2017.

M. Brody and R. Emerson, The effect of wavelength and intensity of light on the proportion of pigments in Porphyridium cruentum, Am. J. Bot, vol.46, pp.433-440, 1959.

C. ,

J. P. Cadoret and O. Bernard, La production de biocarburant lipidique avec des microalgues : promesses et défis, La Société de Biologie, vol.202, pp.201-211, 2008.

P. Capek, M. Matulováa, and B. Combourieu, The extracellular proteoglycan produced by Rhodella grisea, Int. J. Biol. Macromol, vol.43, pp.390-393, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00325920

. A. Cawsep, The determination of nitrate in soil solutions by ultraviolet spectrometry, Analyst, vol.62, pp.311-315, 1967.

R. M. Chaloub, N. M. Motta, S. P. De-araujo, P. F. De-aguiar, and A. F. Da-silva, Combined effects of irradiance, temperature and nitrate concentration on phycoerythrin content in the microalga Rhodomonas sp. (Cryptophyceae), Algal Res, vol.8, pp.89-94, 2015.

B. Cheirsilp, Y. Mandik, and P. Prasertsan, Evaluation of optimal conditions for cultivation of marine Chlorella sp. as potential sources of lipids, exopolymeric substances and pigments, Aquacult. Int, vol.24, pp.313-326, 2016.

B. Cheirsilp and S. Torpee, Enhanced growth and lipid production of microalgae under mixotrophic culture condition: Effect of light intensity, glucose concentration and fed-batch cultivation, Bioresour. Technol, vol.110, pp.510-516, 2012.

C. Chen, H. Chang, and J. Chang, Producing carbohydrate-rich microalgal biomass grown under mixotrophic conditions as feedstock for biohydrogen production, Int. J. Hydrogen Energ, vol.41, pp.4413-4420, 2016.

C. Chen, S. Ho, C. Liu, and J. Chang, Enhancing lutein production with Chlorella sorokiniana

, Mb-1 by optimizing acetate and nitrate concentrations under mixotrophic growth, J. Taiwan Inst. Chem. Eng, vol.79, pp.88-96, 2017.

D. Chen, X. Z. Wu, and Z. Y. Wen, Sulfated polysaccharides and immune response: Promoter or inhibitor? Panminerva Med, 2008.

F. Chen, Y. Zhang, and S. Guo, Growth and phycocyanin formation of Spirulina platensis in photoheterotrophic culture, Biotechnol. Lett, vol.18, pp.603-608, 1996.

F. Chen and Y. Zhang, High cell density mixotrophic culture of Spirulina platensis on glucose for phycocyanin production using a fed-batch system, Enzyme Microb. Technol, vol.20, pp.221-224, 1997.

S. Chinnasamy, B. Ramakrishnan, A. Bhatnagar, and K. C. Das, Biomass Production Potential of a Wastewater Alga Chlorella vulgaris ARC 1 under Elevated Levels of CO2 and Temperature, Int. J. Mol. Sci, vol.10, pp.518-532, 2009.

Y. Chisti, Biodiesel from microalgae, Biotechnol. Adv, vol.25, pp.294-306, 2007.

Y. Chisti, Large-Scale Production of Algal Biomass: Raceway Ponds, Algae Biotechnol, pp.21-40, 2016.

Y. Chisti, Raceways-based production of algal crude oil, Microalgal biotechnology: Potential and production-de Gruyter, pp.113-146, 2012.

M. Chmit, H. Kanaan, J. Habib, M. Abbass, A. Mcheik et al., Antibacterial and antibiofilm activities of polysaccharides, essential oil, and fatty oil extracted from Laurus nobilis growing in Lebanon Asian Pacific, Asian Pac J. Trop. Med, vol.7, pp.546-552, 2014.

K. Chokshi, I. Pancha, K. Trivedi, B. George, R. Maurya et al., Biofuel potential of the newly isolated microalgae Acutodesmus dimorphus under temperature induced oxidative stress conditions, Bioresour. Technol, vol.180, pp.162-171, 2015.

R. E. Cian, S. R. Drago, F. S. De-medina, and O. Martinez-augustin, Proteins and Carbohydrates from Red Seaweeds: Evidence for Beneficial Effects on Gut Function and Microbiota, Mar. Drugs, vol.13, pp.5358-5383, 2015.

L. Cobrado, A. Silva-dias, M. M. Azevedo, C. Pina-vaz, and A. G. Rodrigues, In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections, J. Antimicrob. Chemother, vol.68, pp.126-130, 2013.

E. Cohen and S. M. Arad, A closed system for outdoor cultivation of Porphyridium, vol.18, pp.59-67, 1989.

Z. Cohen, H. A. Norman, and Y. M. Heimer, Microalgae as a source of omega-3 fatty acids, World Rev. Nutr, vol.77, pp.1-31, 1995.

E. Costa, S. Silva, F. Tavaria, and M. Pintado, Antimicrobial and Antibiofilm Activity of Chitosan on the Oral Pathogen Candida albicans, Pathogens, vol.3, pp.908-919, 2014.

D. Silva, A. F. Lourenço, S. O. Chaloub, and R. M. , Effects of nitrogen starvation on the photosynthetic physiology of a tropical marine microalga Rhodomonas sp

, Aquat. Bot, vol.91, pp.291-297, 2009.

K. Dandamudi, T. Muppaneni, N. Sudasinghe, T. Schaub, F. Holguin et al., Co-liquefaction of mixed culture microalgal strains under sub-critical water conditions, Bioresour. Technol, vol.236, pp.129-137, 2017.

P. Das, W. Lei, S. Aziz, and J. Obbard, Enhanced algae growth in both phototrophic and mixotrophic culture under blue light, Bioresour. Technol, vol.102, pp.3883-3887, 2011.

J. De, M. F. Raposo, A. M. De-morais, and R. M. De-morais, Influence of sulphate on the composition and antibacterial and antiviral properties of the exopolysaccharide from Porphyridium cruentum, Life Scc, vol.101, pp.56-63, 2014.

J. De, M. F. Raposo, A. M. De-morais, and R. M. De-morais, Marine polysaccharides from algae with potential biomedical applications, Mar. drugs, vol.13, pp.2967-3028, 2015.

J. De, M. F. Raposo, R. M. De-morais, and A. M. De-morais, Bioactivity and applications of sulphated polysaccharides from marine microalgae, Mar. Drugs, vol.11, pp.233-252, 2013.

L. E. De-bashan, A. Trejo, V. A. Huss, J. P. Hernandez, and Y. Bashan, Chlorella sorokiniana UTEX 2805, a heat and intense, sunlight-tolerant microalga with potential for removing ammonium from wastewater, Bioresour. Technol, vol.99, pp.4980-4989, 2008.

C. Delattre, G. Pierre, C. Laroche, and P. Michaud, Production, extraction and characterization of microalgal and cyanobacterial exopolysaccharides, Biotechnol. Adv, vol.34, pp.1159-1179, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01658391

H. F. Dillon, A. Somanchi, and K. Rao, Methods and compositions for cholesterol reduction in mammals, 2006.

H. F. Dillon, A. Zaman, A. G. Day, and A. Coragliotti, Microalgae-derived compositions for improving the health and appearance of skin, US20150140051A1, 2014.

P. S. Dixon and . Morphology, Biology of the Rhodophyta, p.45, 1973.

. S. Dodgsonk and R. G. Price, A note on the determination of the ester sulphate content of sulphated polysaccharides, Biochem. J, vol.84, pp.106-110, 1962.

. Duboism, K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith, Colorimetric method for determination of sugars and Related Substances, Anal. Chem, vol.28, pp.350-356, 1956.

A. Ducret, W. Sidler, G. Frank, and H. Zuber, The complete amino acid sequence of Rphycocyanin-I ? and ? subunits from the red alga Porphyridium cruentum, Eur. J. Biochem, vol.221, pp.563-580, 1994.

C. Dupré, J. C. Guary, and D. Grizeau, Effect of photon fluence rate, nitrogen limitation and nitrogen recovery on the level of phycoerythrin in the unicellular alga Rhodosorus marinus (Rhodophyceae), Physiol. Plant, vol.92, pp.521-527, 1994.

I. Dvir, R. Chayoth, U. Sod-moriah, S. Shany, A. Nyska et al., Soluble polysaccharide and biomass of red microalgaPorphyridiumsp. alter intestinal morphology and reduce serum cholesterol in rats, Br. J. Nutr, vol.84, pp.469-476, 2000.

L. V. Evans, Electron microscopical observations on a new red algal unicell, Rhodella maculata gen. nov., sp. nov, Br. Phycol. J, vol.5, pp.1-13, 1970.

L. V. Evans and E. Maureen, Studies on the synthesis and composition of extracellular mucilage in the unicellular red alga Rhodella, J. Cell Sci, vol.16, pp.1-21, 1974.

J. Fabregas, D. Garc?a, M. Fernandez-alonso, A. I. Rocha, P. Gomez-puertas et al.,

A. Otero and J. Coll, In vitro inhibition of the replication of haemorrhagic septicaemia virus (VHSV) and African swine fever virus (ASFV) by extracts from marine microalgae, Antivir. Res, vol.44, pp.67-73, 1999.

J. Fabregas, D. García, T. Lamela, and A. Otero, Mixotrophic production of phycoerythrin and exopolysaccharide by the microalga P.cruentum, Crypto. Algol, vol.20, pp.89-94, 1999.

B. Farges, C. Laroche, J. F. Cornet, and C. G. Dussap, Spectral kinetic modeling and long-term behaviour assessment of Arthrospira platensis growth in photobioreactor under red (620nm) light illumination, Biotechnol. Prog, vol.25, pp.151-162, 2009.

M. Fisher, I. Gokhman, . Picku, and A. Zamir, A Salt-resistant Plasma Membrane Carbonic Anhydrase Is Induced by Salt in Dunaliella salina, J. Biol. Chem, vol.271, pp.17718-17723, 1996.

M. M. Fuentes, G. G. Fernandez, J. A. Pérez, and J. L. Guerrero, Biomass nutrient profiles of the microalga Porphyridium cruentum, Food Chem, vol.70, pp.345-353, 2000.

M. M. Fuentes, J. L. S?nchez, J. M. Sevilla, F. G. Fern?ndez, J. A. Pérez et al., Outdoor continuous culture of Porphyridium cruentumin a tubular photobioreactor: quantitative analysis of the daily cyclic variation of culture parameters, J. Biotechnol, vol.70, pp.271-288, 1999.

G. ,

C. Gaignard, N. Gargouch, P. Dubessay, C. Delattre, G. Pierre et al.,

S. Abdelkafi and P. Michaud, New Horizons in Culture and Valorization of Red Microalgae, Biotechnol. Adv, vol.37, pp.193-222, 2019.

C. Gaignard, V. Macao, C. Gardarin, L. Picton, C. Rihouey et al., The red microalga Flintiella sanguinaria as a new exopolysaccharide producer, J. Appl. Phycol, pp.1-12, 2018.
URL : https://hal.archives-ouvertes.fr/hal-01866674

A. Galvan and E. Fernández, Eukaryotic nitrate and nitrite transporters, Cell. Mol. Life Sci, vol.58, pp.225-233, 2001.

E. Gantt and S. F. Conti, The ultrastructure of Porphyridium cruentum, J. Cell Biol, vol.26, pp.365-381, 1965.

E. Gardeva, R. Toshkova, K. Minkova, and L. Gigova, Cancer Protective Action

. Polysaccharide, Derived from Red Microalga Porphyridium Cruentum A Biological Background, Biotechnol. Biotech. Eq, pp.783-787, 2009.

Z. Gardian, L. Bumber, A. Schrofel, M. Herbstova, J. Nebesarova et al., Organisation of photosystem I and photosystem II in red alga Cyanidium caldarium: Encounter of cyanobacterial and higher plant concept, Biochim. Biophys. Acta. Bioenerg, vol.1767, pp.725-731, 2007.

C. Gee and K. Niyogi, The carbonic anhydrase CAH1 is an essential component of the carbonconcentrating mechanism in Nannochloropsis oceanica, Proc. Natl. Acad. Sci. USA, vol.114, pp.4537-4542, 2017.

B. George, I. Pancha, C. Desai, K. Chokshi, C. Paliwal et al., Effects of different media composition, light intensity and photoperiod on morphology and physiology of freshwater microalgae Ankistrodesmus falcatus-a potential strain for biofuel production, Bioresour. Technol, vol.171, pp.367-374, 2014.

S. Geresh, S. Arad, and A. Shefer, Chemically crosslinked polysaccharide of the red microalga Rhodella reticulata-an ion exchanger for toxic metal ions, J. Carbohydr. Chem, vol.16, pp.703-708, 1997.

S. Geresh and S. Arad, The extracellular polysaccharides of the red microalgae: Chemistry and rheology, Bioresour. Technol, vol.38, pp.195-201, 1991.

S. Geresh, S. M. Arad, O. Levy-ontman, and W. Zhang, Isolation and characterization of polyand oligosaccharides from the red microalga Porphyridium sp, Carbohydr. Res, vol.344, pp.343-349, 2009.

S. Geresh, O. Dubinsky, S. M. Arad, and D. Christiaen, Structure of a 3-O-(?-Dglucopyranosyluronic acid)-L-galactopyranose, an aldobiouronic acid isolated from the polysaccharides of various unicellular red algae, Carbohydr. Res, vol.208, pp.301-305, 1990.

S. Geresh, N. Lupescu, and S. M. Arad, Fractionation and partial characterization of the sulphated polysaccharide of Porphyridium, Phytochemistry, vol.31, pp.4181-4186, 1992.

S. Geresh, A. Mamontov, and J. Weinstein, Sulfation of extracellular polysaccharides of red microalgae: preparation, characterization and properties, J. Biochem. Bioph. Meth, vol.50, pp.179-187, 2002.

J. T. Gerlach, H. M. Diepolder, R. Zachoval, N. H. Gruener, M. C. Jung et al., Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance, Gastroenterology, vol.125, pp.80-88, 2003.

A. Ginzberg, M. Cohen, U. A. Sod-moriah, S. Shany, A. Rosenshtrauch et al., Chickens fed with biomass of the red microalga Porphyridium sp. have reduced blood cholesterol level and modified fatty acid composition in egg yolk, J. Appl. Phycol, vol.12, pp.325-330, 2000.

A. N. Glazer, Light harvesting by phycobilisomes, Annu. Rev. Biophys. Biophys. Chem, vol.14, p.47, 1985.

A. N. Glazer, Phycobiliproteins -a family of valuable, widely used fluorophores, J. Appl. Phycol, vol.6, pp.105-112, 1994.

A. N. Glazer and L. Stryer, Phycofluor probes, Trends Biochem. Sci, vol.9, pp.423-427, 1984.

V. Gloaguen, G. Ruiz, H. Morvan, A. Mouradi-givernaud, E. Maes et al., The extracellular polysaccharide of Porphyridium sp.: An NMR study of lithium-resistant oligosaccharidic fragments, Carbohydr. Res, vol.339, pp.97-103, 2004.

C. J. Gobler, D. L. Berry, S. T. Dyhrman, S. W. Wilhelm, A. Salamov et al.,

A. Terry, J. Pangilinan, E. A. Lindquist, S. Lucas, I. T. Paulsen et al.,

S. C. Talmage, E. A. Walker, F. Koch, A. M. Burson, M. A. Marcoval et al.,

K. J. Coyne, G. M. Berg, E. M. Bertrand, M. A. Saito, V. N. Gladyshev et al., Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics, Proc. Natl. Acad. Sci. U.S.A, vol.108, pp.4352-4357, 2011.

I. Godos, J. L. Mendoza, F. G. Acién, E. Molina, C. J. Banks et al., Evaluation of carbon dioxide mass transfer in raceway reactors for microalgae culture using flue gases, Bioresour. Technol, vol.153, pp.307-314, 2014.

E. Gómez-ordóñez and P. Rupérez, FTIR-ATR spectroscopy as a tool for polysaccharide identification in edible brown and red seaweeds, Food Hydrocoll, vol.25, pp.1514-1520, 2011.

W. Gross and C. Schnarrenberger, Heterotrophic growth of two strains of the acido-thermophilic red alga Galdieria sulphuraria, Plant Cell. Physiol, vol.36, pp.633-638, 1995.

A. C. Guedes, H. M. Amaro, and F. X. Malcata, Microalgae as sources of carotenoids, Mar. Drugs, vol.9, pp.625-644, 2011.

M. Guiry, How many species of algae are there?, J. Phycol, vol.48, pp.1057-1063, 2012.

M. A. Guzmán-murillo and F. Ascencio, Anti-adhesive activity of sulphated exopolysaccharides of microalgae on attachment of the red sore disease-associated bacteria and Helicobacter pylori to tissue culture cells, Lett. Appl. Microbiol, vol.30, pp.473-478, 2000.

R. Harun, M. Singh, G. M. Forde, and M. K. Danquah, Bioprocess engineering of microalgae to produce a variety of consumer products, Renewable Sustainable Energy Rev, vol.14, pp.1037-1047, 2010.

M. Hasui, M. Matsuda, K. Okutani, and S. Shigeta, In vitro antiviral activities of sulfated polysaccharides from a marine microalga (Cochlodinium polykrikoides) against human immunodeficiency virus and other enveloped viruses, Int. J. Biol. Macromol, vol.17, pp.293-297, 1995.

B. Hazra, S. Biswas, and N. Mandal, Antioxidant and free radical scavenging activity of Spondias pinnata, BMC Complement Altern. Med, vol.8, p.63, 2008.

F. He, Y. Yang, G. Yang, and L. Yu, Studies on antibacterial activity and antibacterial mechanism of a novel polysaccharide from Streptomyces virginia H03, vol.21, pp.1257-1262, 2010.

A. S. Hemlata and T. Fatma, Extraction, purification and characterization of phycoerythrin from Michrochaete and its biological activities, Biocatal. Agric. Biotechnol, vol.13, pp.84-89, 2018.

C. Hirabaru, A. Izumo, S. Fujiwara, Y. Tadokoro, T. Shimonaga et al., The primitive rhodophyte Cyanidioschyzon merolae contains a semiamylopectin-type, but not an amylose-type, alphaglucan, Plant Cell Physiol, vol.51, pp.682-693, 2010.

S. Hirabayashi, A. Prillutsky, and H. Sadamatsu, Method of culturing algae capable of producing phototrophic pigments, highly unsaturated fatty acids, or polysaccharides at high concentration, vol.6579714, 1999.

S. H. Ho, C. Y. Chen, and J. S. Chang, Effect of light intensity and nitrogen starvation on CO2 fixation and lipid/carbohydrate production of an indigenous microalga Scenedesmus obliquus CNW-N, Bioresour. Technol, vol.113, pp.244-252, 2013.

S. J. Hong and C. G. Lee, Evaluation of central metabolism based on a genomic database of Synechocystis PCC6803, Biotechnol. Bioprocess Eng, vol.12, pp.165-173, 2007.

Q. Hu, Environmental effects on cell composition, Biotechnology and Applied Phycology, pp.83-93, 2005.

C. Huang, M. Miao, S. Janaswamy, B. R. Hamaker, X. Li et al., Polysaccharide Modification through Green Technology: Role of Endodextranase in Improving the Physicochemical Properties of (1?3)(1?6)-?-D-Glucan, J. Agric. Food Chem, vol.63, pp.6450-6456, 2015.

L. Huang, M. Shen, X. Zhang, L. Jiang, Q. Song et al., Effect of high-pressure microfluidization treatment on the physicochemical properties and antioxidant activities of polysaccharide from Mesona chinensis Benth, Carbohydr. Polym, vol.200, pp.191-199, 2018.

M. Huleihel, V. Ishanu, J. Tal, and S. M. Arad, Antiviral effect of red microalgal polysaccharides on Herpes simplex and Varicella zoster viruses, J. Appl. Phycol, vol.13, pp.127-134, 2001.

F. Hussain, S. Z. Shah, W. Zhou, M. ;. Iqbal, and M. J. Merrett, Dissolved inorganic carbon utilization and the development of extracellular carbonic anhydrase by the marine diatom Phaeodactylum tricornutum, Références bibliographiques I Iglesias-rodriguez, vol.170, pp.163-168, 1997.

J. G. Ivanova, L. V. Kabaivanova, P. D. Petro, and S. N. Yankova, Optimization strategies for improved growth, polysaccharide production and storage of the red microalga Rhodella reticulate, Bulg. Chem. Commun, vol.47, pp.167-174, 2015.

, J

W. Jahn, J. Steinbiss, and K. Zetsche, Light intensity adaptation of the phycobiliprotein content of the red alga Porphyridium, Planta, vol.161, pp.536-539, 1984.

S. W. Jeffrey, S. W. Wright, and M. Zapata, Microalgal classes and their signature pigments, Phytoplankton pigments Characterization, Chemotaxonomy and Applications in Oceanography, 2011.

G. Jiao, G. Yu, J. Zhang, and H. S. Ewart, Chemical structures and bioactivities of sulphated polysaccharides from marine algae, Mar. Drugs, vol.9, pp.196-223, 2011.

S. Jubeau, L. Marchal, J. Pruvost, P. Jaouen, J. Legrand et al., High pressure disruption: a two-step treatment for selective extraction of intracellular components from the microalga Porphyridium cruentum, J. Appl. Phycol, vol.25, pp.983-989, 2013.

A. Juneja, R. M. Ceballos, and G. S. Murthy, Effects of Environmental Factors and Nutrient Availability on the Biochemical Composition of Algae for, Biofuels Production: A Review. Energies, vol.6, pp.4607-4638, 2013.

M. Ka?uráková, P. Capek, V. Sasinkova, N. Wellner, and A. Ebringerova, FT-IR study of plant cell wall model compounds: Pecticpolysaccharides and hemicelluloses, Carbohydr. Polym, vol.43, p.195, 2000.

I. Karkouch, O. Tabbene, D. Gharbi, M. A. Ben-mlouka, S. Elkahoui et al.,

C. P. Jouenne, T. Limam, and F. , Antioxidant, antityrosinase and antibiofilm activities of synthesized peptides derived from Vicia faba protein hydrolysate: A powerful agents in cosmetic application, Ind. Crops Prod, vol.109, pp.310-319, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02326081

S. Kathiresan, R. Sarada, S. Bhattacharya, and G. A. Ravishankar, Culture media optimization for growth and phycoerythrin production from Porphyridium purpureum, Biotechnol. Bioeng, vol.96, pp.456-463, 2007.

M. D. Kavitha, S. Kathiresan, S. Bhattacharya, and R. Sarada, Culture media optimization of Porphyridium purpureum: production potential of biomass, total lipids, Arachidonic and eicosapentaenoic acid, J. Food Sci. Technol, vol.53, pp.2270-2278, 2016.

O. Kesraoui, M. N. Marzouki, T. Maugard, and F. Limam, In vitro evaluation of antioxidant activities of free and bound phenolic compounds from Posidonia oceanica

, Afr. J. Biotechnol, vol.10, pp.3176-3185, 2011.

H. M. Kim, C. H. Oh, and H. J. Bae, Comparison of red microalgae (Porphyridium cruentum) culture conditions for bioethanol production, Bioresour. Technol, vol.233, pp.44-50, 2017.

M. Kim, J. H. Yim, S. Y. Kim, H. S. Kim, W. G. Lee et al., In vitro inhibition of influenza A virus infection by marine microalga-derived sulfated polysaccharide p-KG03, Antivir. Res, vol.93, pp.253-259, 2012.

R. Kivelä, L. Pitkänen, P. Laine, V. Aseyev, and T. Sontag-strohm, Influence of homogenisation on the solution properties of oat ?-glucan, Food Hydrocolloid, vol.24, 2010.

D. Kova?, O. Babi?, I. Milovanovi?, A. Mi?an, and J. Simeunovi?, The production of biomass and phycobiliprotein pigments in filamentous cyanobacteria: the impact of light and carbon sources, Appl. Biochem. Micro, vol.53, pp.539-545, 2017.

G. T. Kraft and W. J. Woelkerling, Rhodophyta-systematics and biology, pp.41-85, 1990.

P. M. Kris-etherton, J. A. Grieger, and T. D. Etherton, Dietary reference intakes for DHA and EPA

, Prostaglandins, Leukot. Essent. Fatty Acids, vol.81, pp.99-104, 2009.

M. Kröger and F. Müller-langer, Impact of heterotrophic and mixotrophic growth of microalgae on the production of future biofuels, Biofuels, vol.2, pp.145-151, 2011.

H. Kylin, Übereine marine Porphyridium-Art, Kungl. FysiografiskaSällskapetsi Lund Förhandlingar, vol.7, pp.119-123, 1937.

U. K. Laemmli, Cleavage of structural proteins during assembly of the head of bacteriophage T4, Nature, vol.5, pp.227-680, 1970.

P. P. Lamers, M. Janssen, R. C. De-vos, R. J. Bino, and R. H. Wijffels, Carotenoid and fatty acid metabolism in nitrogen-starved Dunaliella salina, a unicellular green microalga, J. Biotechnol, vol.162, pp.21-27, 2012.

A. W. Larkum, Photosynthesis and Light Harvesting in Algae, pp.67-87, 2016.

M. Latasa and E. Berdalet, Effect of nitrogen or phosphorus starvation on pigment composition of cultured Heterocapsa sp, J. Plankton Res, vol.16, pp.83-94, 1994.

D. Lavanchy, Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures, J. Viral Hepat, vol.11, pp.97-107, 2004.

E. Lee, M. Jalalizadeh, and Q. Zhang, Growth kinetic models for microalgae cultivation: A review, Algal Res, vol.12, pp.497-512, 2015.

Y. Lee, Microalgal mass culture systems and methods: Their limitation and potential, J. Appl. Phycol, vol.13, pp.307-315, 2001.

A. L. Lehninger, D. L. Nelson, and M. M. Cox, Lehninger Principles of biochemistry, 2005.

L. Levy and E. Gant, Development of photosynthetic activity in Porphyridium purpureum (Rhodophyta) following nitrogen starvation, J. Phycol, vol.26, pp.62-68, 1990.

L. A. Leyva, Y. Bashan, A. Mendoza, and L. E. De-bashan, Accumulation of fatty acids in Chlorella vulgaris under heterotrophic conditions in relation to activity of acetyl-CoA carboxylase, temperature, and co-immobilization with Azospirillum brasilense, Naturwissenschaften, vol.101, pp.819-830, 2014.

H. Li, Z. Li, S. Xiong, H. Zhang, N. Li et al., Pilot-scale isolation of bioactive extracellular polymeric substances from cell-free media of mass microalgal cultures using tangential-flow ultrafiltration, Process Biochem, vol.46, pp.1104-1109, 2011.

Q. Y. Li, X. S. Gao, Y. Sun, Q. Q. Zhang, R. T. Song et al., Isolation and characterization of a sodium-dependent phosphate transporter gene in Dunaliella viridis, Biochem. Biophys. Res. Commun, vol.340, pp.95-104, 2006.

S. H. Li, B. B. Xia, C. Zhang, J. Cao, and L. H. Bai, Cloning and characterization of a phosphate transporter gene in Dunaliella salina, J. Basic Microbiol, vol.52, pp.429-436, 2012.

X. Li, H. Xu, and Q. Wu, Large-scale biodiesel production from microalga Chlorella protothecoides through heterotrophic cultivation in bioreactors, Biotechnol. Bioeng, vol.98, pp.764-771, 2007.

Y. Liang, Producing liquid transportation fuels from heterotrophic microalgae, Appl. Energy, vol.104, pp.860-868, 2013.

Y. Liang, N. Sarkany, and Y. Cui, Biomass and lipid productivities of Chlorella vulgaris under autotrophic, heterotrophic and mixotrophic growth conditions, Biotechnol. Lett, vol.31, pp.1043-1049, 2009.

H. Lichtenthaler, Chlorophylls and carotenoids: Pigments of photosynthetic biomembranes, Methods Enzymol, vol.148, pp.350-382, 1987.

Q. Lin, N. Gu, and J. Lin, Effect of ferric ion on nitrogen consumption, biomass and oil accumulation of a Scenedesmus rubescens-like microalga, Bioresour. Technol, vol.112, pp.242-247, 2012.

S. Liqin, C. Wang, and S. Lei, Effects of Light Regime on Extracellular Polysaccharide Production by Porphyridium Cruentum Cultured in Flat Plate Photobioreactors

, Bioinf. Biomed. Eng. 2nd, pp.1488-1491, 2008.

H. Liu and H. P. Fang, Extraction of extracellular polymeric substances (EPS) of sludges, J. Biotechnol, vol.95, pp.249-256, 2002.

L. Liu, Y. Zhao, X. Jiang, X. Wang, and W. Liang, Lipid accumulation of Chlorella pyrenoidosa under mixotrophic cultivation using acetate and ammonium, Bioresour. Technol, vol.262, pp.342-346, 2018.

C. A. Llewellyn, E. S. Egeland, and G. Johnsen, Phytoplankton Pigments: Characterization, Chemotaxonomy and Applications in Oceanography, 2011.

C. G. López, M. García, F. Fernández, C. Bustos, Y. Chisti et al., Protein measurements of microalgal and cyanobacterial biomass, Bioresour. Technol, vol.101, pp.7587-7591, 2010.

S. O. Lourenço, E. Barbarino, J. Mancini-filho, K. P. Schinke, and E. Aidar, Effects of different nitrogen sources on the growth and biochemical profile of 10 marine microalgae in batch culture: an evaluation for aquaculture, Phycologia, vol.41, pp.158-168, 2002.

J. Lowrey, M. Brooks, and P. Mcginn, Heterotrophic and mixotrophic cultivation of microalgae for biodiesel production in agricultural wastewaters and associated challenges-a critical review, J. Appl. Phycol, vol.27, pp.1485-1498, 2015.

O. H. Lowry, N. J. Rosenbrough, A. L. Farr, and R. J. Randall, Protein measurement with the folin phenol reagent, J. Biol. Chem, vol.193, p.265, 1951.

G. A. Lutzu, L. Zhang, Z. Zhang, and T. Liu, Feasibility of attached cultivation for polysaccharides production by Porphyridium cruentum, Bioprocess. Biosyst. Eng, vol.40, 2017.

E. Manirafasha, T. Ndikubwimana, X. Zeng, Y. Lu, and K. Jing, Phycobiliprotein: Potential microalgae derived pharmaceutical and biological reagent, Biochem. Eng. J, vol.109, pp.282-296, 2016.

G. D. Manrique and F. M. Lajolo, FT-IR spectroscopy as a tool for measuring degree of methyl esterification in pectins isolated from ripening papaya fruit, Postharvest Biol. Tech, vol.25, 2002.

A. Marcati, A. V. Ursu, C. Laroche, N. Soanen, L. Marchal et al., Extraction and fractionation of polysaccharides and B-phycoerythrin from the microalga Porphyridium cruentum by membrane technology, Algal Res, vol.5, pp.258-263, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01658671

Y. Maréchal, Interaction configurations of H2O molecules in a protein (Stratum Corneum) by infrared spectrometry, J. Mol. Struct, vol.416, pp.133-143, 1997.

J. Marquardt, Effects of carotenoid-depletion on the photosynthetic apparatus of a Galdieria sulphuraria (Rhodophyta) strain that retains its photosynthetic apparatus in the dark, J. Plant Physiol, vol.152, pp.372-380, 1998.

J. Marquardt and A. M. Rehm, Porphyridium purpureum (Rhodophyta) from red and green light: characterization of photosystem I and determination of in situ fluorescence spectra of the photosystems, J. Photochem. Photobiol. Biology, vol.30, pp.49-56, 1995.

F. J. Marquez, K. Sasaki, T. Kakizono, N. Nishio, and S. Nagai, Growth characteristics of Spirulina platensis in mixotrophic and heterotrophic conditions, J. Ferm. Bioeng, vol.76, pp.408-410, 1993.

L. R. Martinez, M. R. Mihu, M. Tar, R. J. Cordero, G. Han et al.,

J. D. Nosanchuk, Demonstration of antibiofilm and antifungal efficacy of chitosan against candidal biofilms, using an in vivo central venous catheter model, J. Infect. Dis, vol.201, pp.1436-1440, 2010.

M. J. Martinez, D. Olmo, L. M. Benito, and P. B. , Antiviral activities of polysaccharides from natural sources, Stud. Nat. Prod. Chem, vol.30, pp.393-418, 2005.

J. Masojídek, G. Torzillo, and M. Koblí?ek, Handbook of Microalgal Culture: Applied Phycology and Biotechnology, 2013.

S. M. Matsui, N. Muizzudin, S. M. Arad, and K. Marenus, Sulfated polysaccharides from red microalgae anti-inflammatory properties in vitro and in vivo, Appl. Biochem. Biotechnol, vol.104, pp.13-22, 2003.

D. A. Mccracken and J. R. Cain, Amylose in floridean starch, New Phytol, vol.88, pp.67-71, 1981.

J. Mcneill, F. R. Barrie, W. R. Buck, V. Demoulin, W. Greuter et al., International Code of Nomenclature for algae, fungi, and plants (Melbourne Code) adopted by the Eighteenth International Botanical Congress Melbourne, 2011.

S. G. Mihova, D. I. Georgiev, and K. M. Minkov, Phycobiliproteins in Rhodella reticulate and photoregulatory effects on their content, J. Biotechnol, vol.48, pp.251-257, 1996.

S. G. Mihova, K. M. Minkova, G. D. Petkov, and D. I. Georgiev, Thermal and photoregulation of the lipid and fatty acid content in the cells of Porphyridium sordidum, Comptes rendus de l'académie bulgare des sciences: sciences mathématiques et naturelles, vol.50, pp.111-114, 1997.

S. R. Miller and R. W. Castenholtz, Ecological Physiology of Synechococcussp. Strain SH-94-5, a Naturally Occurring Cyanobacterium Deficient in Nitrate Assimilation, Appl. Environ. Microbiol, vol.67, pp.3002-3009, 2001.

M. A. Monsoor, U. Kalapathy, and A. Proctor, Determination of polygalacturonic acid content in pectin extracts by diffuse reflectance Fourier transform infrared spectroscopy, Food Chem, vol.74, pp.233-238, 2001.

. Montreuilj, G. Spik, A. Chosson, E. Segard, and N. Scheppler, Methods of study of the structure of glycoproteins, J. Pharm. Belg, vol.18, pp.529-546, 1963.

D. Morales-s?nchez, R. Tinoco, J. Kyndt, and A. Martinez, Heterotrophic growth of Neochloris oleoabundans using glucose as a carbon source, Biotechnol. Biofuels, vol.6, pp.1-12, 2013.

T. Moriyama, N. Mori, and N. Sato, Activation of oxidative carbon metabolism by utritional enrichment by photosynthesis and exogenous organic compounds in the red alga Cyanidioschyzon merolae: evidence for heterotrophic growth, vol.4, p.559, 2015.

J. V. Moroney, A. Ruby, and R. A. Ynalvez, Proposed Carbon Dioxide Concentrating Mechanism in Chlamydomonas reinhardtii, Eukaryot. Cell, vol.6, pp.1251-1259, 2007.

J. F. Morot-gaudry, Assimilation de l'azote chez les plantes: aspects physiologique, biochimique et moléculaire, INRA, pp.1-422, 1997.

M. Munier, S. Jubeau, A. Wijaya, M. Morançais, J. Dumay et al., Physicochemical factors affecting the stability of two pigments: R-phycoerythrin of
URL : https://hal.archives-ouvertes.fr/hal-01935733

, Grateloupia turuturu and B-phycoerythrin of Porphyridium cruentum, Food Chem, vol.150, pp.400-407, 2014.

M. Munier, M. Morançais, J. Dumay, P. Jaouen, and J. Fleurence, One-step purification of Rphycoerythrin from the red edible seaweed Grateloupia turuturu, J. Chromatogr. B Analyt

, Technol. Biomed. Life Sci, vol.15, pp.23-29, 2015.

T. Murugan and . Radhamadhavan, Screening for Antifungal and Antiviral activity of Cphycocyanin from Spirulina platensis, J. Pharm. Res, vol.4, pp.4161-4163, 2011.

T. Murugan, Screening for Antifungal and Antiviral activity of C-phycocyanin from Spirulina platensis, 2011.

J. Naval, B. Antia, R. Berland, D. J. Bonin, and S. Y. Maestrini, Effects of urea concentration in supporting growth of certain marine microplanktonic algae, Phycologia, vol.16, pp.105-111, 1977.

A. H. Neilson and R. A. Lewin, The uptake and utilization of organic carbon by algae: an essay in comparative biochemistry, Phycologia, vol.13, pp.227-264, 1974.

N. A. Nimer, M. J. Merrett, and C. Brownlee, Inorganic carbon transport in relation to culture age and inorganic carbon concentration in a high-calcifying strain of emiliania huxleyi (prymnesiophyceae), J. Phycol, vol.32, pp.813-818, 1996.

G. Nosálová, P. Capek, T. Matáková, S. Nosá?, D. Fle?ková et al., Antitussive activity of an extracellular Rhodella Grisea proteoglycan on the mechanically induced cough reflex, Carbohydr. Polym, vol.87, pp.752-756, 2012.

J. Nzayisenga, K. Eriksson, and A. Sellstedt, Mixotrophic and heterotrophic production of lipids and carbohydrates by a locally isolated microalga using wastewater as a growth medium

, Bioresour. Technol, vol.257, pp.260-265, 2018.

C. Oesterhelt, C. Schnarrenberger, and W. Gross, Characterization of a sugar/polyol-uptake system in the red alga Galdieria sulphuraria, Eur. J. Phycol, vol.34, pp.271-277, 1999.

S. H. Oh, J. G. Han, Y. Kim, J. H. Ha, S. S. Kim et al.,

W. B. Yoon, S. Y. Lee, D. H. Kang, and H. Y. Lee, Lipid production in Porphyridium cruentum grown under different culture conditions, J. Biosci. Bioeng, vol.108, pp.429-434, 2009.

E. Ono and J. L. Cuello, Selection of optimal microalgae species for CO2 sequestration, Proceedings of SecondAnnual Conference on Carbon Sequestration, 2003.

H. T. Osborn and C. C. Akoh, Structured lipids novel fats with medical, nutraceutical, and food applications, Compr. Rev. Food Sci. F, vol.3, pp.110-120, 2002.

Q. Pan, M. Chen, J. Li, Y. Wu, C. Zhen et al., Antitumor function and mechanism of phycoerythrin from Porphyra haitanensis, Biol. Res, vol.46, pp.87-95, 2013.

R. Pangestuti and S. Kim, Biological activities and health benefit effects of natural pigments derived from marine algae, J. Funct. Foods, vol.3, pp.255-266, 2011.

K. Park, C. Whitney, J. Mcnichol, K. Dickinson, S. Macquarrie et al.,

K. E. Wilson, S. J. O'leary, and P. J. Mcginn, Mixotrophic and photoautotrophic cultivation of 14 microalgae isolates from Saskatchewan, Canada: potential applications for wastewater remediation for biofuel production, J. Appl. Phycol, vol.24, pp.339-348, 2012.

A. K. Patel, C. Laroche, A. Marcati, A. V. Ursu, S. Jubeau et al.,

P. Michaud, Separation and fractionation of exopolysaccharides from Porphyridium cruentum, Bioresour. Technol, vol.145, pp.345-350, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01658773

S. N. Patel, R. R. Sonani, K. Jakharia, B. Bhastana, H. M. Patel et al.,

D. Madamwar, Antioxidant activity and associated structural attributes of Halomicronema phycoerythrin, Int. J. Biol. Macromol, vol.111, pp.359-369, 2018.

Y. Pengzhan, L. Ning, L. Xiguang, Z. Gefei, Z. Quanbin et al., Antihyperlipidemic effects of different molecular weight sulfated polysaccharides from Ulva pertusa (Chlorophyta), Pharmacol. Res, vol.48, pp.543-549, 2003.

R. Pérez, Ces algues qui nous entourent, p.272, 1997.

O. Perez-garcia and Y. Bashan, Microalgal Heterotrophic and Mixotrophic Culturing for Biorefining: From Metabolic Routes to Techno-economics, Algal Biorefineries, 2015.

O. Perez-garcia, F. Escalante, L. De-bashan, and Y. Bashan, Heterotrophic cultures of microalgae: Metabolism and potential products, Water Res, vol.45, pp.11-36, 2011.

. Peterab, . Delattrec, . Pierreg, . Wadouachia, . Elboutachfaitir et al., Characterization of arabinogalactan-rich mucilage from Cereus triangularis cladodes, Carbohydr. Polym, vol.127, pp.372-380, 2015.

G. Pierre, V. Sopena, C. Juin, A. Mastouri, M. Graber et al., Antibacterial activity of a sulfated galactan extracted from the marine alga Chaetomorpha aerea against Staphylococcus aureus, Biotechnol. Bioproc. E, vol.16, pp.937-945, 2011.

O. Pignolet, S. Jubeau, C. Vaca-garcia, and P. Michaud, Highly valuable microalgae: biochemical and topological aspects, J. Ind. Microbiol. Biotechnol, vol.40, pp.781-796, 2013.
URL : https://hal.archives-ouvertes.fr/hal-02067092

T. L. Pownall, C. C. Udenigwe, and R. E. Aluko, Effects of cationic property on the in vitro antioxidant activities of pea protein hydrolysate fractions, Food Res. Int, vol.44, pp.1069-1074, 2011.

L. M. Prescott, J. P. Harley, and D. A. Klein, Microbiologie (2è édition française), pp.1-1137, 2003.

A. Rahaoui, Écophysiologie de Rhodella violacea (Rhodophyta) : production et propriétés structurales des exopolysaccharides et de l'amidon floridéen, pp.1-130, 1999.

C. A. Raines, Increasing Photosynthetic Carbon Assimilation in C3 Plants to Improve Crop Yield: Current and Future Strategies, Plant Physiol, vol.155, pp.36-42, 2011.

S. M. Raines, H. S. Rane, S. M. Bernardo, J. L. Binder, S. A. Lee et al., Deletion of vacuolar proton translocating ATPase voa isoforms clarifies the role of vacuolar pH as a determinant of virulence-associated traits in Candida albicans, J. Biol. Chem, vol.288, pp.6190-6201, 2013.

G. Ramage, K. Vandewalle, J. L. Lopez-ribot, and B. L. Wickes, The filamentation pathway controlled by theEfg1 regulator protein is required for normal biofilm formation and development in Candida albicans, FEMS Microbiol. Lett, vol.214, pp.95-100, 2002.

R. Ramaraj, D. D. Tsai, and P. H. Chen, Chlorophyll is not Accurate Measurement for Algal Biomass, Chiang Mai J. Sci, vol.40, pp.547-555, 2013.

J. Ramus, The capture and transduction of light energy, Blackwell Scientific Publications, pp.458-492, 1981.

J. Ramus, The production of extracellular polysaccharide by unicellular red alga Porphyridium aerugineum, J. Phycol, vol.8, pp.97-111, 1972.

M. Ras, J. P. Steyer, and O. Bernard, Temperature effect on microalgae: a crucial factor for outdoor production, Rev. Environ. Sci. Biotechnol, vol.12, pp.153-164, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00852286

C. Ratledge, K. Kanagachandran, A. J. Anderson, D. J. Grantham, and J. C. Stephenson, Production of docosahexaenoic acid by Crypthecodinium cohnii grown in a pH-auxostat culture with acetic acid as principal carbon source, Lipids, vol.36, pp.1241-1246, 2001.

J. A. Raven, M. Giordano, and . Combined-nitrogen, The Physiology of Microalgae, Developments in Applied Phycology, 2016.

B. A. Read, J. Kegel, M. J. Klute, A. Kuo, S. C. Lefebvre et al.,

A. Monier, A. Salamov, J. Young, M. Aguilar, J. M. Claverie et al.,

E. K. Herman, Y. C. Lin, J. Napier, H. Ogata, A. F. Sarno et al., Pan genome of the phytoplankton Emiliania underpins its global distribution, Int. J. Pharma. Biosci, vol.2, pp.446-454, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01074841

C. Rigano, Studies on nitrate reductase from Cyanidium caldarium, Arch. Mikrobiol, vol.76, pp.265-276, 1971.

C. Rigano and U. Violante, Effect of heat treatment on the activity in vitro of nitrate reductase from Cyanidium caldarium, Biochim. Biophys. Acta, vol.256, pp.524-532, 1972.

M. Rigobello-masini, E. Aidar, and J. Masini, Extra and intracelular activities of carbonic anhydrase of the marine microalga Tetraselmis gracilis (Chlorophyta), Braz. J. Microbiol, vol.34, pp.267-272, 2003.

M. Ritz, J. C. Thomas, A. Spilar, and A. L. Etienne, Kinetics of photoacclimatation in response to a shift to high light irradiance of the red algae Rhodella violacea adapted to low irradiance, Plant Physiol, vol.123, pp.1415-1425, 2000.

S. Robu, A. C. Aprotosoaie, A. Miron, O. Cioanc?, U. St?nescu et al., In vitro antioxidant activity of ethanolic extracts from some lavandula species cultivated in Romania, Farmacia, p.60, 2012.

C. Romay, R. Gonzalez, N. Ledon, D. Remirez, and V. Rimbau, phycocyanin: a biliprotein with antioxidant, anti-inflammatory and neuroprotective effects, Curr. Protein Pept. Sci, vol.4, pp.207-216, 2003.

J. Ropellato, M. M. Carvalho, L. G. Ferreira, M. D. Noseda, C. R. Zuconelli et al.,

D. R. Ducatti, J. C. Kenski, P. L. Nasato, S. M. Winnischofer, and M. E. Duarte, Sulfated heterorhamnans from the green seaweed Gayralia oxysperma: partial depolymerization, chemical structure and antitumor activity, Carbohydr. Polym, vol.117, pp.476-485, 2015.

C. Rotatore, B. Colman, and M. Kuzma, The active uptake of carbon dioxide by the marine diatoms Phaeodactylum ticornutum and Cyclotella sp, Plant Cell. Environ, vol.18, pp.913-918, 1995.

M. Roussel, A. Villay, F. Delbac, P. Michaud, C. Laroche et al., Antimicrosporidian activity of sulphated polysaccharides from algae and their potential to control honeybee nosemosis, Carbohydr. Polym, vol.133, pp.213-220, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01247322

S. Roy, C. Llewellyn, E. Skartstad, and G. Johnsen, Phytoplankton pigments characterization, chemotaxonomy and applications in oceanography, 2011.

I. Sadovskaya, A. Souissi, S. Souissi, T. Grard, P. Lencel et al., Chemical structure and biological activity of a highly branched (1 ? 3,1 ? 6)-?-d-glucan from Isochrysis galbana, Carbohydr. Polym, vol.111, pp.139-148, 2014.

T. Sakurai, M. Aoki, X. Ju, T. Ueda, Y. Nakamura et al.,

A. Minoda, Profiling of lipid and glycogen accumulations under different growth conditions in the sulfothermophilic red alga Galdieria sulphuraria, Bioresour. Technol, vol.200, pp.861-866, 2016.

F. Salah, Y. Elghoul, . Mahdhia, H. Majdoub, N. Jarroux et al., Effect of the deacetylation degree on the antibacterial and antibiofilm activity of acemannan from Aloe vera, Ind. Crop. Prod, vol.103, pp.13-18, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02110164

M. C. Santiago-santos, T. Ponce-noyola, R. Olvera-ram??ez, J. Ortega-lópez, and R. O. Cañizares-villanueva, Extraction and purification of phycocyanin from Calothrix sp, Process Biochem, vol.39, pp.2047-2052, 2004.

B. H. Sarmadi and A. Ismail, Antioxidative peptides from food proteins: a review, Peptides, vol.31, pp.1949-1956, 2012.

N. Sato, T. Moriyama, N. Mori, and M. Toyoshima, Lipid metabolism and potentials of biofuel and high added-value oil production in red algae, World J. Microbiol. Biotechnol, vol.33, 2017.

S. Schilling and C. Oesterhelt, Structurally reduced monosaccharide transporters in an evolutionarily conserved red alga, Biochem. J, vol.406, pp.325-331, 2007.

R. A. Schmidt, M. G. Wiebe, and N. T. Eriksen, Heterotrophic high cell density fed-batch cultures of the phycocyanin producing red alga Galdieria sulphuraria, Biotechnol. Bioeng, vol.90, 2005.

J. Scott, E. C. Yang, J. A. West, A. Yokoyama, H. J. Kim et al., On the genus Rhodella, the emended orders Dixoniellales and Rhodellales with a new order Glaucosphaerales (Rhodellophyceae, Rhodophyta), Algae, vol.26, pp.277-288, 2011.

J. L. Scott, A. Yokoyama, C. Billard, J. Fresnel, Y. Hara et al., Neorhodella cyanea, a new Genus in the Rhodellophyceae (Rhodophyta), Phycologia, vol.47, pp.560-572, 2008.

B. Serive, E. Nicolau, J. B. Bérard, R. Kaas, V. Pasquet et al., Community analysis of pigment patterns from 37 microalgae strains reveals new carotenoids and porphyrins characteristic of distinct strains and taxonomic groups, Plos One, p.12, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01656311

F. Shahidi and Y. Zhong, Measurement of antioxidant activity, J. Funct. Foods, vol.18, pp.757-781, 2015.

S. Shen, S. Jia, Y. Wu, R. Yan, Y. Lin et al., Effect of culture conditions on the physicochemical properties and antioxidant activities of polysaccharides from Nostoc flagelliforme, Carbohydr. Polym, vol.198, pp.426-433, 2018.

T. Shimonaga, S. Fujiwara, M. Kaneko, A. Izumo, S. Nihei et al., Variation in Storage a-Polyglucans of Red Algae: Amylose and Semi-Amylopectin Types in Porphyridium and Glycogen Type in Cyanidium, Mar. Biotechnol, vol.9, pp.192-202, 2007.

T. Shimonaga, M. Konishi, Y. Oyama, S. Fujiwara, A. Satoh et al., Variation in Storage ?-Glucans of the Porphyridiales (Rhodophyta), vol.49, pp.103-116, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00198812

B. Sialve and J. P. Steyer, Les microalgues, promesses et défis, Innov. Agron, vol.26, pp.25-39, 2013.

P. C. Silva and R. L. Moe, Taxonomic classification of algae, Seaweed ecology and phycology, pp.301-308, 1997.

A. Silva-dias, A. Palmeira-de-oliveira, I. M. Miranda, J. Branco, L. Cobrado et al.,

M. Soares, J. A. Queiroz, C. Pina-vaz, and A. G. Rodrigues, Anti-biofilm activity of low-molecular Références bibliographiques weight chitosan hydrogel against Candida species, Med. Microbiol. Immunol, vol.203, pp.25-33, 2014.

S. Singh, S. M. Arad, and A. Richmond, Extracellular polysaccharide production in outdoor mass cultures of Porphyridium sp. in flat plate glass reactors, J. Appl. Phycol, vol.12, pp.269-275, 2000.

J. K. Sloth, M. G. Wiebe, and N. T. Eriksen, Accumulation of phycocyanin in heterotrophic and mixotrophic cultures of the acidophilic red alga Galdieria sulphuraria, Enzyme Microb

, Technol, vol.38, pp.168-175, 2006.

N. Soanen, E. D. Silva, C. Gardarin, P. Michaud, and C. Laroche, Improvement of exopolysaccharide production by Porphyridium marinum, Bioresour. Technol, vol.213, pp.231-238, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01658288

R. R. Sonani, N. K. Singh, J. Kumar, D. Thakar, and D. Madamwar, Concurrent purification and antioxidant activity of phycobiliproteins from Lyngbya sp. A09DM: An antioxidant and antiaging potential of phycoerythrin in Caenorhabditis elegans, Process Biochem, vol.49, pp.1757-1766, 2014.

M. Song and H. Pei, The growth and lipid accumulation of Scenedesmus quadricauda during batch mixotrophic/heterotrophic cultivation using xylose as a carbon source, Bioresour. Technol, vol.263, pp.525-531, 2018.

B. Soni, B. Kalavadia, U. Trivedi, and D. Madamwar, Extraction, purification and characterization of phycocyanin from Oscillatoria quadripunctulata-Isolated from the rocky shores of Bet-Dwarka, Process Biochem, vol.41, pp.2017-2023, 2006.

B. Soni, U. Trivedi, and D. Madamwar, A novel method of single step hydrophobic interaction chromatography for the purification of phycocyanin from Phormidium fragile and its characterization for antioxidant property, Bioresour. Technol, vol.99, pp.188-194, 2008.

R. Stein, W. Gross, and C. Schnarrenberger, Characterization of a xylitol dehydrogenase and a Darabitol dehydrogenase from the thermo-and acidophilic red alga Galdieria sulphuraria, Planta, vol.202, pp.487-493, 1997.

D. B. Stengel, S. Connan, and Z. A. Popper, Algal chemodiversity and bioactivity: sources of natural variability and implications for commercial application, Biotechnol. Adv, vol.29, 2011.

L. Sun, C. Wang, Q. Shi, and C. Ma, Preparation of different molecular weight polysaccharides from Porphyridium cruentum and their antioxidant activities, Int. J. Biol. Macromol, vol.45, pp.42-47, 2009.

L. Sun, L. Wang, and Y. Zhou, Immunomodulation and an titumor activities of different molecular-weight polysaccharides from Porphyridium cruentum, Carbohydr. Polym, vol.87, pp.1206-1210, 2012.

L. Sun, S. Wang, L. Chen, and X. Gong, Promising fluorescent probes from phycobiliproteins

, IEEE J. Sel. Top. Quantum Electron, vol.9, pp.177-188, 2003.

R. Sun and J. Tomkinson, Characterization of hemicelluloses obtained by classical and ultrasonically assisted extractions from wheat straw, Carbohydr. Polym, vol.50, pp.263-271, 2002.

P. Syrett and H. Wong, The fermentation of glucose by Chlorella vulgaris, Biochem. J, vol.89, 1963.

A. Tabernero, E. M. Martín-del-valle, and M. A. Galán, Evaluating the industrial potential of biodiesel from a microalgae heterotrophic culture: scale-up and economics, Biochem. Eng. J, vol.63, pp.104-115, 2012.

Z. Tang, Z. Jilu, B. Ju, W. Li, S. Wen et al., One-step chromatographic procedure for purification of B-phycoerythrin from Porphyridium cruentum, Protein Expr. Purif, vol.123, pp.70-74, 2016.

T. Tannin-spitz, M. Bergman, D. Van-moppes, S. Grossman, and S. M. Arad, Antioxidant activity of the polysaccharide of the red microalga Porphyridium sp, J. Appl. Phycol, vol.17, pp.215-222, 2005.

W. G. Telford, M. W. Moss, J. P. Morseman, and F. Allnutt, Cyanobacterial stabilized phycobilisomes as fluorochromes for extracellular antigen detection by flow cytometry, J. Immunol. Methods, vol.254, pp.13-30, 2001.

A. Villay, F. L. De-filippis, L. Picton, D. L. Cerf, . Vialc et al., Comparison of polysaccharide degradations by dynamic high-pressure homogenization. Food Hydrocoll, vol.27, pp.278-286, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01866761

A. Villay, C. Laroche, D. Roriz, H. El-alaoui, F. Delbacb et al., Optimisation of culture parameters for exopolysaccharides production by the microalga Rhodella violacea, Bioresour. Technol, vol.146, pp.732-735, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01071051

A. Vonshak, Z. Cohen, and A. Richmond, The feasibility of mass cultivation of Porphyridium, Biomass, vol.8, pp.13-25, 1985.

A. Vonshak and G. Torzillo, Handbook of Microalgal Culture: Biotechnology and Applied Phycology, Environmental Stress Physiology, 2004.

J. Wang, H. Yang, and F. Wang, Mixotrophic Cultivation of Microalgae for Biodiesel Production: Status and Prospects, Appl. Biochem. Biotechnol, vol.172, pp.3307-3329, 2014.

J. Wang, Q. Zhang, Z. Zhang, and Z. Li, Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica, Int. J. Biol. Macromol, vol.42, pp.127-132, 2008.

L. Wei, Y. Xin, D. Wang, X. Jing, Q. Zhou et al., Nannochloropsis plastid and mitochondrial phylogenomes reveal organelle diversification mechanism and intragenus phylotyping strategy in microalgae, Genomics, vol.14, p.53, 2013.

M. L. Wells, P. Potin, J. S. Craigie, J. A. Raven, S. S. Merchant et al.,

M. E. Camire and S. H. Braxley, Algae as nutritional and functional food sources: revisiting our understanding, J. Appl. Phycol, vol.29, pp.949-982, 2017.

J. Wiethaus, A. W. Busch, T. Dammeyer, and T. Frankenberg-dinkel, Phycobiliproteins in Prochlorococcus marinus: Biosynthesis of pigments and their assembly into proteins, Eur. J. Cell. Biol, vol.89, pp.1005-1010, 2010.

F. Wollman and J. Girard-bascou, Une algue pour l'étude de la génétique des organites:Chlamydomonas reinhardti, Med. Sci, vol.10, pp.1-14, 1994.

F. Xie, W. Zhang, X. Lan, S. Gong, J. Wu et al., Effects of high hydrostatic pressure and high pressure homogenization processing on characteristics of potato peel waste pectin, Carbohydr. Polym, vol.196, pp.474-482, 2018.

H. Xu, X. Miao, and Q. Wu, High quality biodiesel production from a microalga Chlorella protothecoides by heterotrophic growth in fermenters, J. Biotechnol, vol.126, pp.499-507, 2006.

A. Yamaoka, Y. Ozawa, Y. Ueno, T. Endo, Y. Morimoto et al., Cyanidioschyzon merolae ferredoxin: a high resolution crystal structure analysis and its thermal stability, FEBS Lett, vol.585, pp.1299-1302, 2011.

S. Yamashita, Y. Sugita-konishi, and M. Shimizu, In vitro Bacteriostatic Effects of Dietary Polysaccharides, Food Sci. Technol. Res, vol.7, pp.262-264, 2001.

C. Yang, Q. Hua, and K. Shimizu, Carbon metabolism during growth under photoautotrophic, mixotrophic and autotrophic/dark-heterotrophic conditions, Biochem. Eng. J, vol.6, pp.87-102, 2000.

E. C. Yang, J. Scott, J. A. West, E. Orlova, D. Gauthier et al., New taxa of the Porphyridiophyceae (Rhodophyta): Timspurckia oligopyrenoides gen. et sp. nov. and Erythrolobus madagascarensis sp, pp.604-616, 2010.

Y. Yang and K. Gao, Effects of CO2 concentrations on the freshwater microalgae, Chlamydomonas reinhardtii, Chlorella pyrenoidosa and Scenedesmus obliquus (Chlorophyta), J. Appl. Phycol, vol.15, pp.379-389, 2003.

S. Yarnpakdee, S. Benjakul, H. G. Kristinsson, and H. Kishimura, Antioxidant and sensory properties of protein hydrolysate derived from Nile tilapia (Oreochromis niloticus) by oneand two-step hydrolysis, J. Food Sci. Technol, vol.52, pp.3336-3349, 2015.

A. Yaron, E. Cohen, and S. M. Arad, Stabilization of aloe vera gel by interaction with sulfated polysaccharides from red microalgae and with xanthan gum, J. Agric. Food Chem, vol.40, pp.1316-1320, 1992.

Y. Ye, Y. Huang, A. Xia, Q. Fu, Q. Liao et al., Optimizing culture conditions for heterotrophic-assisted photoautotrophic biofilm growth of Chlorella vulgaris to simultaneously improve microalgae biomass and lipid productivity, Bioresour. Technol, vol.270, pp.80-87, 2018.

Y. Ye, L. Clech, P. Chen, V. Fane, and A. G. , Evolution of fouling during cross flow filtration of model EPS solutions, J. Membr. Sci, vol.264, pp.190-199, 2005.

J. Yim, E. Son, S. Pyo, and H. Lee, Novel sulfated polysaccharide derived from red-tide microalga Gyrodinium impudicum strain KG03 with immunostimulating activity in vivo, Mar. Biotechnol, vol.7, pp.331-338, 2005.

K. Ying, D. J. Gilmour, and W. B. Zimmerman, Effects of CO2 and pH on Growth of the Microalga Dunaliella salina, J. Microb. Biochem. Technol, vol.6, pp.167-173, 2014.

H. S. Yoon, K. M. Müller, R. G. Sheath, F. D. Ott, and D. Bhattacharya, Defining the major lineages of red algae (Rhodophyta), J. Phycol, vol.42, pp.482-492, 2006.

T. You and S. M. Barnett, Effect of light quality on production of extracellular polysaccharides and growth rate of Porphyridium cruentum, Biochem. Eng. J, vol.19, pp.251-258, 2004.

S. Yu, A. Blennow, M. Bojko, F. Madsen, C. E. Olsen et al., Physico-chemical characterization of floridean starch of red algae, Starch, vol.54, pp.66-74, 2002.

L. Zhang, X. Ye, S. Xue, X. Zhang, D. Liu et al., Effect of high-intensity ultrasound on the physicochemical properties and nanostructure of citrus pectin, J. Sci. Food Agr, vol.93, pp.2028-2036, 2013.

K. H. Zhao, R. J. Porra, H. Scheer, ;. Phycobiliproteins, S. Roy et al.,

G. Johnsen, Phytoplankton pigments Characterization, Chemotaxonomy and Applications in Oceanography, 2011.

G. Zhou, Y. Sun, H. Xin, Y. Zhang, Z. Li et al., In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus, Pharmacol. Res, 2004.

G. F. Zhou, W. X. Sheng, W. D. Yao, and C. H. Wang, Effect of low molecular ?-carrageenan from

, Chondrus ocellatus on antitumor H-22 activity of 5-Fu, Pharmacol. Res, vol.53, pp.129-124, 2006.

X. L. Zhu, A. F. Chen, and Z. B. Lin, Ganoderma lucidum polysaccharides enhance the function of immunological effector cells in immunosuppressed mice, J. Ethnopharmacol, vol.111, pp.219-226, 2007.

B. H. Zimm, The Scattering of Light and the Radial Distribution Function of High Polymer Solutions, J. Chem. Phys, vol.16, 1948.