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L. O. Rea, J. Dico, G. Marc, G. Nicola, B. François et al., PhD 5 , Marc POCARD, MD, PhD 1,2 Affiliations : 1 Service de Chirurgie Digestive et Cancérologique, Hôpital Lariboisière, Carcinose Angiogenèse et Recherche Translationnelle (CART), vol.5

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L. O. Rea, . Dico, H. Md-service-de-chirurgie-digestive-et-cancérologique, and . Lariboisière, AP-HP

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F. T. Paris,

L. O. Rea, . Dico, T. Julien, J. Marc, G. Marc et al., Data and statistical analysis and interpretation: Rea LO DICO, Marc POCARD Drafting and editing of manuscript: All authors Critical manuscript review and approval of final version: All authors in Japan in terms of epidemiology and clinical response to the surgery, rea.lo-dico@aphp.fr Conflicts of interest: None to declare Sources of support: No funding -No financial relationships

, We planned a novel therapeutic strategy for Western Country combining administration of IP docetaxel with IV FOLFOX-4 (5-fluorouracil and oxaliplatin) in patients with non-resectable PC from gastric cancer in order to facilitate the setup of a phase I trial. The main endpoint of our pilot study was evaluated the feasibility and safety of this neoadjuvant bidirectional treatement, More, the oral S-1 is considered as inefficient on European Caucasian patient and is not delivered in Europe

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