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Contribution à la biomécanique de la régénération osseuse : modélisation, simulation et applications

Abstract : This work deals with modelization of bane remodeling. We present first a madel thal accounts for the cellular res panse to a mechanical stimulus in a general case at a continuous scale. This madel is applied to 2D and 3D geometries at macroscopic scale to mimic real cases, as weil as 2D trabecular-type geometries at mesoscopic scale. However, the complexity of bane remodeling does not allow a unique approach. Th us, the thesis work is focused on the particular case of orthodontie bane re mode ling. A new specifie madel is developed accounting for the influence of the periodontal ligament on orthodontie bane remodeling by integrating the oxygen concentration effect controling the evolutions of cellular densities. The cellular experimental data in vitro are extracted from the literature, and serve as input data of the developed madel in arder to ablain the evolution of bane density around the root of a 3D cylindrical tooth.
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https://tel.archives-ouvertes.fr/tel-02317749
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Submitted on : Wednesday, October 16, 2019 - 12:11:07 PM
Last modification on : Thursday, March 5, 2020 - 3:32:59 PM
Long-term archiving on: : Friday, January 17, 2020 - 3:23:10 PM

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  • HAL Id : tel-02317749, version 1

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Camille Spingarn. Contribution à la biomécanique de la régénération osseuse : modélisation, simulation et applications. Biomécanique [physics.med-ph]. Université de Strasbourg, 2019. Français. ⟨NNT : 2019STRAD010⟩. ⟨tel-02317749⟩

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