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, A549 cells silenced for ARIH1 were treated for 16 hr with the indicated amounts of CCCP or cisplatin (25 mM), and apoptosis was assessed using propidium iodide staining and flow cytometry measuring sub-G1 DNA fragmentation
were treated for 48 hr with cisplatin (25 mM) or etoposide (25 mM) or irradiated with UV (40 J/m 2 ). Plasma membrane permeabilization (i.e., cell death) was assessed using DAPI staining and analyzed by flow cytometry ,
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, France 5 Immunogenomics and Inflammation Research Unit EA 4130, pp.1052-5286
, Laboratoire d'Excellence TOUCAN; Programme Hospitalo-Universitaire en Cancérologie CAPTOR
,
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69007 Lyon, France *equal contribution 10 Corresponding authors: Els Verhoeyen (els.verhoeyen@unice.fr/els.verhoeyen@ens-lyon.fr) and Jean-Ehrland Ricci (ricci@unice.fr) 11 Lead contact: Els Verhoeyen ,
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