The significance of biological heterogeneity, Cancer and Metastasis Review, vol.9, pp.1-20, 1990. ,
The roots of cancer: stem cells and the basis for tumor heterogeneity, BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, vol.35, pp.253-260, 2013. ,
Defining heterogeneity within bacterial populations via single cell approaches, BioEssays, vol.38, pp.782-790, 2016. ,
Darwinism : an exposition of the theory of natural selection, with some of its applications, p.1889 ,
A New Model for SOS-induced Mutagenesis: How RecA Protein Activates DNA Polymerase V, Critical reviews in biochemistry and molecular biology, vol.45, pp.171-184, 2010. ,
Vibrio cholerae Triggers SOS and Mutagenesis in Response to a Wide Range of Antibiotics: a Route towards Multiresistance, Antimicrobial Agents and Chemotherapy, vol.55, pp.2438-2441, 2011. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01423615
Phase variation: how to create and coordinate population diversity, Current Opinion in Microbiology. Cell regulation, vol.14, pp.205-211, 2011. ,
The genetics of Neisseria species, Annual Review of Genetics, vol.48, pp.405-431, 2014. ,
A functional perspective on phenotypic heterogeneity in microorganisms, Nature Reviews Microbiology, vol.13, pp.497-508, 2015. ,
A Simple Screen to Identify Promoters Conferring High Levels of Phenotypic Noise, PLOS Genetics 4, vol.12, pp.1-6, 2008. ,
Bacterial Persistence as a Phenotypic Switch, Science 305, vol.5690, pp.1622-1625, 2004. ,
Treatment of Staphylococcal Infections with Penicillin by Intermittent Sterilisation, The Lancet, vol.244, pp.497-500, 1944. ,
Bacterial biofilms: from the Natural environment to infectious diseases, Nature Reviews Microbiology, vol.2, issue.2, pp.95-108, 2004. ,
Biofilm susceptibility to antimicrobials, Advances in Dental Research, vol.11, pp.160-167, 1997. ,
Adaptive immune responses in Staphylococcus aureus biofilm-associated chronic rhinosinusitis, Allergy, vol.66, pp.1449-1456, 2011. ,
Molecular architecture and assembly principles of Vibrio cholerae biofilms, Science, vol.337, pp.236-239, 2012. ,
Does replication-induced transcription regulate synthesis of the myriad low copy number proteins of Escherichia coli?, In: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, vol.17, pp.987-997, 1995. ,
Exact stochastic simulation of coupled chemical reactions, The Journal of Physical Chemistry, vol.81, pp.2340-2361, 1977. ,
Stochastic Gene Expression in a Single Cell, Science 297, vol.5584, pp.1183-1186, 2002. ,
Stochastic Switching of Cell Fate in Microbes, Annual Review of Microbiology, vol.69, pp.381-403, 2015. ,
A stochastic singlemolecule event triggers phenotype switching of a bacterial cell, Science, vol.322, pp.442-446, 2008. ,
A Genetic Switch: Gene Control and Phage Lambda, 1986. ,
Bimodal gene expression in noncooperative regulatory systems, Proceedings of the National Academy of Sciences, vol.107, pp.22096-22101, 2010. ,
How to make a biological switch, Journal of Theoretical Biology, vol.203, pp.117-133, 2000. ,
Construction of a genetic toggle switch in Escherichia coli, Nature 403, vol.6767, pp.339-342, 2000. ,
A bistable switch and anatomical site control Vibrio cholerae virulence gene expression in the intestine, PLoS pathogens, vol.6, pp.1-23, 2010. ,
Bacterial Toxin-Antitoxin Systems: More Than Selfish Entities?, In: PLoS Genetics, vol.5, pp.1-6, 2009. ,
Specialized Persister Cells and the Mechanism of Multidrug Tolerance in Escherichia coli, Journal of Bacteriology, vol.186, pp.8172-8180, 2004. ,
A General Model for Toxin-Antitoxin Module Dynamics Can Explain Persister Cell Formation in E. coli, PLoS Computational Biology 9, vol.8, pp.1-17, 2013. ,
Toxinantitoxin modules as bacterial metabolic stress managers, Trends in Biochemical Sciences, vol.30, pp.672-679, 2005. ,
Stability and instability in the lysogenic state of phage lambda, Journal of Bacteriology, vol.192, pp.6064-6076, 2010. ,
Biased partitioning of the multidrug efflux pump AcrAB-TolC underlies longlived phenotypic heterogeneity, Science, vol.356, pp.311-315, 2017. ,
Foodborne illness acquired in the United States-major pathogens, Emerging Infectious Diseases, vol.17, pp.7-15, 2011. ,
Stabilization of cooperative virulence by the expression of an avirulent phenotype, Nature, vol.494, pp.353-356, 2013. ,
Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation, PLOS Biology, vol.12, pp.1-8, 2014. ,
Phenotypic Diversity, Population Growth, and Information in Fluctuating Environments, Science, vol.309, pp.2075-2078, 2005. ,
Explaining microbial genomic diversity in light of evolutionary ecology, Nature Reviews. Microbiology, vol.12, pp.263-273, 2014. ,
Mutations of bacteria from virus sensitivity to virus resistance, Genetics 28, vol.491, pp.491-511, 1943. ,
Resistance to Chemotherapy: Patient Variability and Cellular Heterogeneity". In: Cancer Research 74, vol.17, pp.4663-4670, 2014. ,
Microfluidics: Fluid physics at the nanoliter scale, Reviews of Modern Physics, vol.77, pp.977-1026, 2005. ,
The origins and the future of microfluidics, Nature, vol.442, pp.368-373, 2006. ,
Microfluidics and single-cell microscopy to study stochastic processes in bacteria, Current Opinion in Microbiology, vol.43, pp.186-192, 2018. ,
Monitoring dynamics of single-cell gene expression over multiple cell cycles, Molecular Systems Biology, vol.1, pp.1-6, 2005. ,
Robust Growth of Escherichia coli, Current Biology, vol.20, pp.1099-1103, 2010. ,
Cell-Size Control and Homeostasis in Bacteria, Current Biology, vol.25, pp.385-391, 2015. ,
Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging, Proceedings of the National Academy of Sciences, vol.114, pp.9170-9175, 2017. ,
Synchronous long-term oscillations in a synthetic gene circuit, Nature, vol.538, pp.514-517, 2016. ,
MicrofluidicsAssisted Cell Screening (MACS): an automated platform for singlecell microscopy of suspension cultures, Nature Protocols, vol.13, pp.170-194, 2018. ,
Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells, Nature Communications, vol.7, p.11641, 2016. ,
Microfluidic approach for encapsulation via double emulsions, Current Opinion in Pharmacology, vol.18, pp.35-41, 2014. ,
Droplet-based microfluidic platforms for the encapsulation and screening of Mammalian cells and multicellular organisms, Chemistry & Biology, vol.15, pp.427-437, 2008. ,
URL : https://hal.archives-ouvertes.fr/hal-02148746
Stabilisers for water-in-fluorinated-oil dispersions: Key properties for microfluidic applications, Current Opinion in Colloid & Interface Science, vol.20, pp.183-191, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01213318
A simple method for isolating individual microbes, Journal of Bacteriology, vol.68, pp.258-259, 1954. ,
Recherches sur un baccilus megatherium lysogene, Annales de l'institut Pasteur, vol.78, p.739, 1950. ,
Droplet microfluidics for microbiology: techniques, applications and challenges, Lab on a Chip, vol.16, pp.2168-2187, 2016. ,
Droplet microfluidic technology for single-cell high-throughput screening, Proceedings of the National Academy of Sciences, vol.106, pp.14195-14200, 2009. ,
Parallelized ultra-high throughput microfluidic emulsifier for multiplex kinetic assays, Biomicrofluidics, vol.9, pp.1-11, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01179083
Optofluidic ultrahigh-throughput detection of fluorescent drops, Lab Chip, vol.15, pp.1417-1423, 2015. ,
Active droplet sorting in microfluidics: a review, Lab on a Chip, vol.17, pp.751-771, 2017. ,
Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution, PLOS ONE, vol.11, p.152395, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01400779
A Millifluidic Study of Cell-to-Cell Heterogeneity in GrowthRate and Cell-Division Capability in Populations of Isogenic Cells of Chlamydomonas reinhardtii, PLOS ONE, vol.10, pp.1-28, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01230006
Encapsulating bacteria in agarose microparticles using microfluidics for high-throughput cell analysis and isolation, ACS chemical biology, vol.6, pp.260-266, 2011. ,
Microfluidic screening of antibiotic susceptibility at a single-cell level shows the inoculum effect of cefotaxime on E. coli, Lab on a Chip, vol.18, pp.3668-3677, 2018. ,
Bacterial growth and adaptation in microdroplet chemostats, Angewandte Chemie, vol.52, pp.1-10, 2013. ,
Segmented flow generation by chip reactors for highly parallelized cell cultivation, Biosensors & Bioelectronics, vol.19, pp.1421-1428, 2004. ,
Growing Unculturable Bacteria, Journal of Bacteriology, vol.194, pp.4151-4160, 2012. ,
Development of a realtime PCR-based method for rapid differential identification of Mycobacterium species, Letters in Applied Microbiology, vol.46, pp.101-106, 2008. ,
Enhanced sequencing coverage with digital droplet multiple displacement amplification, Nucleic Acids Research, vol.44, pp.1-9, 2016. ,
Bacterial Growth: Constant Obsession with dN/dt, Journal of Bacteriology, vol.181, pp.7405-7408, 1999. ,
The Growth of Bacterial Cultures, Annual Review of Microbiology, vol.3, pp.371-394, 1949. ,
Dependency on Medium and Temperature of Cell Size and Chemical Composition during Balanced Growth of Salmonella typhimurium, Journal of General Microbiology, vol.19, pp.592-606, 1958. ,
Interdependence of Cell Growth and Gene Expression: Origins and Consequences, Science, vol.330, pp.1099-1102, 2010. ,
Bacterial growth laws and their applications, Current Opinion in Biotechnology, vol.22, pp.559-565, 2011. ,
Growthdependent bacterial susceptibility to ribosome-targeting antibiotics, Molecular Systems Biology, vol.11, issue.3, pp.796-796, 2015. ,
Stochasticity of metabolism and growth at the singlecell level, Nature, vol.514, pp.376-379, 2014. ,
On Age-Dependent Binary Branching Processes, The Annals of Mathematics, vol.55, pp.280-295, 1952. ,
Growth Rate and Generation Time of Bacteria, with Special Reference to Continuous Culture, Journal of General Microbiology, vol.15, pp.492-511, 1956. ,
Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells, Journal of The Royal Society Interface, vol.10, pp.1-11, 2013. ,
Modeling Bacterial Population Growth from Stochastic Single-Cell Dynamics, Applied and Environmental Microbiology, vol.80, pp.5241-5253, 2014. ,
Stochasticity in Colonial Growth Dynamics of Individual Bacterial Cells, Applied and Environmental Microbiology, vol.79, pp.2294-2301, 2013. ,
Kinetics of Single Cells: Observation and Modeling of a Stochastic Process, In: Applied and Environmental Microbiology, vol.72, issue.3, pp.2163-2169, 2006. ,
The Effects of Stochasticity at the Single-Cell Level and Cell Size Control on the Population Growth, Cell Systems, vol.5, pp.358-367, 2017. ,
Universality in stochastic exponential growth, Physical Review Letters, vol.113, pp.1-5, 2014. ,
Scaling laws governing stochastic growth and division of single bacterial cells, Proceedings of the National Academy of Sciences, vol.111, pp.15912-15917, 2014. ,
Phenomenology of stochastic exponential growth, Physical Review E, vol.95, pp.1-12, 2017. ,
Bridging the Timescales of Single-Cell and Population Dynamics, Physical Review X, vol.8, pp.1-14, 2018. ,
Noise-driven growth rate gain in clonal cellular populations, Proceedings of the National Academy of Sciences, vol.113, pp.3251-3256, 2016. ,
Estimating the Generation-Time Distribution of an Age-Dependent Branching Process, Biometrics, vol.30, pp.125-135, 1974. ,
Estimation Theory for ContinuousTime Branching Processes, Sankhy?: The Indian Journal of Statistics, Series A, vol.39, pp.101-123, 1961. ,
Nonparametric estimation of the division rate of an age dependent branching process, Stochastic Processes and their Applications, vol.126, pp.1433-1471, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01102813
Inference for an age-dependent, multitype branching-process model of mast cells, In: Journal of Mathematical Biology, vol.25, pp.203-226, 1987. ,
Pseudo-likelihood estimation for discretely observed multitype Bellman-Harris branching processes, Journal of Statistical Planning and Inference, vol.137, pp.1375-1388, 2007. ,
Inverse problems in systems biology, Inverse Problems, vol.25, pp.1-52, 2009. ,
Inferring fitness landscapes and selection on phenotypic states from single-cell genealogical data, PLOS Genetics, vol.13, pp.1-25, 2017. ,
Parameter inference for stochastic single-cell dynamics from lineage tree data, BMC Systems Biology, vol.11, issue.1, 2017. ,
What Population Reveals about Individual Cell Identity: Single-Cell Parameter Estimation of Models of Gene Expression in Yeast, PLOS Computational Biology, vol.12, pp.1-18, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01248298
Universal microfluidic platform for bioassays in anchored droplets, Lab on a Chip, vol.16, pp.4200-4211, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-02104854
Breaking Anchored Droplets in a Microfluidic Hele-Shaw Cell, Physical Review Applied, vol.3, pp.1-5, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01178874
Rails and anchors: guiding and trapping droplet microreactors in two dimensions, Lab Chip, vol.11, pp.813-821, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00804598
Trapping Microfluidic Drops in Wells of Surface Energy, Physical Review Letters, vol.107, pp.1-4, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00998003
The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation, Lab on a Chip, vol.15, pp.3439-3459, 2015. ,
An approximation theorem for the Poisson binomial distribution, In: Pacific Journal of Mathematics, vol.10, pp.1181-1197, 1960. ,
, Probabilités, analyse des données et statistique. Paris: Editions Technip, 2008.
Development of a facile droplet-based single-cell isolation platform for cultivation and genomic analysis in microorganisms, Scientific Reports, vol.7, pp.1-11, 2017. ,
Microbial phenotypic heterogeneity and antibiotic tolerance, Current Opinion in Microbiology, vol.10, pp.30-38, 2007. ,
Escherichia coli can survive stress by noisy growth modulation, Nature Communications, vol.9, pp.1-11, 2018. ,
Stress and Host Immunity Amplify Mycobacterium tuberculosis Phenotypic Heterogeneity and Induce Nongrowing Metabolically Active Forms, Cell Host & Microbe, vol.17, pp.32-46, 2015. ,
The Promise and Challenge of Digital Biology, Journal of Bioengineering & Biomedical Science, vol.3, issue.3, pp.1-3, 2013. ,
High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number, Analytical Chemistry, vol.83, pp.8604-8610, 2011. ,
Droplet-based Microfluidic Platform for Quantitative Microbiolgy, 2016. ,
Universal Protein Fluctuations in Populations of Microorganisms, Physical Review Letters, vol.108, pp.1-17, 2012. ,
Chapter 3 -Bacterial Growth, Environmental Microbiology, pp.37-54, 2009. ,
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics, Lab on a Chip, vol.8, pp.1265-1272, 2008. ,
Millifluidic droplet analyser for microbiology, Lab on a Chip, vol.11, pp.4057-4062, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00647595
, Escherichia coli Physiology in Luria-Bertani Broth". In: Journal of Bacteriology, vol.189, pp.8746-8749, 2007.
Oxygen availability and the growth of Escherichia coli W3110: A problem exacerbated by scale-up, Bioprocess Engineering, vol.23, pp.487-494, 2000. ,
Oxygen diffusion in poly(dimethyl siloxane) using fluorescence quenching. I. Measurement technique and analysis, In: Journal of Polymer Science: Part A: Polymer Chemistry, vol.24, pp.621-636, 1986. ,
Solute-solvent interactions in perfluorocarbon solutions of oxygen. An NMR study, Journal of the American Chemical Society, vol.103, pp.3733-3738, 1981. ,
Enhanced and homogeneous oxygen availability during incubation of microfluidic droplets, RSC Advances, vol.5, pp.101871-101878, 2015. ,
Estimating Bacterial Growth Parameters by Means of Detection Times, Applied and Environmental Microbiology, vol.65, pp.732-736, 1999. ,
A Comparison of Methods to Measure Fitness in Escherichia coli, PLOS ONE, vol.10, pp.1-11, 2015. ,
Single-Cell Physiology, Annual Review of Biophysics, vol.44, pp.123-142, 2015. ,
, The Surface Evolver". In: Experimental Mathematics, vol.1, issue.2, pp.141-165, 1992.
Gas sorption, diffusion, and permeation in poly(dimethylsiloxane), Journal of Polymer Science Part B: Polymer Physics, vol.38, pp.415-434, 2000. ,
Plaque Formation and Isolation of Pure Lines with Poliomyelitis Viruses, Journal of Experimental Medicine, vol.99, pp.167-182, 1954. ,
Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes, Molecular Systems Biology, vol.14, pp.1-14, 2018. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01967521
Trainable Weka Segmentation: a machine learning tool for microscopy pixel classification, Bioinformatics, vol.33, pp.2424-2426, 2017. ,
Fiji: an open-source platform for biological-image analysis, Nature Methods, vol.9, issue.7, pp.676-682, 2012. ,
Coupling the initiation of chromosome replication to cell size in Escherichia coli, Current Opinion in Microbiology, vol.6, pp.146-150, 2003. ,
Division in Escherichia coli is triggered by a sizesensing rather than a timing mechanism, BMC Biology, vol.12, p.17, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-00981312
Microbial cell individuality and the underlying sources of heterogeneity, Nature Reviews Microbiology, vol.4, issue.8, pp.577-587, 2006. ,
Cell Size Regulation in Bacteria, Physical Review Letters, vol.112, pp.1-5, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01532530
The Kolmogorov-Smirnov Test for Goodness of Fit, Journal of the American Statistical Association, vol.46, pp.68-78, 1951. ,
Distribution of turbidity detection times produced by single cell-generated bacterial populations, Journal of Microbiological Methods, vol.55, pp.821-827, 2003. ,
A Parallel Study on Bacterial Growth and Inactivation, Journal of Theoretical Biology, vol.210, pp.327-336, 2001. ,
TLM-Tracker: software for cell segmentation, tracking and lineage analysis in time-lapse microscopy movies, Bioinformatics, vol.28, pp.2276-2277, 2012. ,
Modelling the variability of lag times and the first generation times of single cells of, International Journal of Food Microbiology, vol.100, pp.13-19, 2005. ,
Bacillus subtilis: from soil bacterium to super-secreting cell factory, In: Microbial Cell Factories, vol.12, p.3, 2013. ,
Improved bacterial baby machine: application to Escherichia coli K-12, In: Journal of Bacteriology, vol.174, pp.3445-3449, 1992. ,
R.A. Fisher and the making of maximum likelihood 1912-1922, In: Statistical Science, vol.12, pp.162-176, 1997. ,
On Quasi-Likelihood Methods and Estimation for Bunching Processes and Heteroscedastic Regression Models, In: Australian Journal of Statistics, vol.34, pp.199-206, 1992. ,
Approximations to the Maximum Likelihood Estimate in Some Pure Birth Processes, Biometrika, vol.78, pp.295-299, 1991. ,
Modeles aleatoires en ecologie et evolution, Collection: Mathematiques et Applications, 2016. ,
Convergence of the Age Distribution in the one-dimensional supercritical age-dependent branching process, The Annals of Probability, vol.4, pp.38-50, 1976. ,
The last generation of bacterial growth in limiting nutrient, BMC Systems Biology, vol.7, pp.1-9, 2013. ,
Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets, Lab on a Chip, vol.13, pp.3707-3713, 2013. ,
Ready for a world without antibiotics? The Pensières Antibiotic Resistance Call to Action, Antimicrobial Resistance and Infection Control, vol.1, issue.11, pp.1-13, 2012. ,
Multidrug-resistant Tuberculosis, Medical Clinics of North America, vol.97, pp.553-579, 2013. ,
Antimicrobial Drug Resistance in Escherichia coli from Humans and Food Animals, Emerging Infectious Diseases, vol.18, pp.741-749, 1950. ,
Where are all the new antibiotics? The new antibiotic paradox, Canadian Journal of Infectious Diseases and Medical Microbiology, vol.16, pp.159-160, 2005. ,
Antibiotics and antibiotic resistance: A bitter fight against evolution, International Journal of Medical Microbiology, vol.303, pp.293-297, 2013. ,
Rapid identification and antimicrobial susceptibility testing reduce antibiotic use and accelerate pathogen-directed antibiotic use, In: Journal of Antimicrobial Chemotherapy, vol.61, pp.428-435, 2007. ,
Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices, Clinical Infectious Diseases, vol.49, pp.1749-1755, 2009. ,
Rapid Diagnosis of Bacterial Meningitis by Real-Time PCR and Fluorescence In Situ Hybridization, Journal of Clinical Microbiology, vol.43, pp.3390-3397, 2005. ,
Urinary Tract Infections: Disease Panorama and Challenges, The Journal of Infectious Diseases, vol.183, pp.1-4, 2001. ,
Digital antimicrobial susceptibility testing using the MilliDrop technology, European Journal of Clinical Microbiology & Infectious Diseases, vol.35, pp.415-422, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01400797
Antibiograms in five pipetting steps: precise dilution assays in sub-microliter volumes with a conventional pipette, Lab on a Chip, vol.16, pp.893-901, 2016. ,
Dynamic Persistence of Antibiotic-Stressed Mycobacteria, Science, vol.339, pp.91-95, 2013. ,
Persister cells, dormancy and infectious disease, Nature Reviews Microbiology, vol.5, pp.48-56, 2007. ,
Microbial Persistence and the Road to Drug Resistance, Cell Host & Microbe, vol.13, pp.632-642, 2013. ,
SOS Response Induces Persistence to Fluoroquinolones in Escherichia coli, PLoS Genetics 5, vol.12, pp.1-9, 2009. ,
Determination of minimum inhibitory concentrations, Journal of Antimicrobial Chemotherapy, vol.48, pp.5-16, 2001. ,
Natural antibiotic susceptibility of Escherichia coli, Shigella, E. vulneris, and E. hermannii strains, Diagnostic Microbiology and Infectious Disease, vol.33, pp.187-199, 1999. ,
Minimal inhibitory concentration of microorganisms causing surgical site infection in referral hospitals in North of Iran, In: Caspian Journal of Intern Medicine, vol.6, pp.34-39, 2011. ,
Evaluation of E-Test for Determination of Antimicrobial MICs for Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients, In: Journal of Clinical Microbiology, vol.33, pp.3191-3193, 1995. ,
, Model List of Essential Medicines, 2017.
The inoculum effect and band-pass bacterial response to periodic antibiotic treatment, Molecular Systems Biology, vol.8, pp.1-11, 2012. ,
The Innate Growth Bistability and Fitness Landscapes of Antibiotic-Resistant Bacteria, Science, vol.342, pp.1068-1078, 2013. ,
Issues in Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents: Kill Curves versus MIC, Antimicrobial Agents and Chemotherapy, vol.48, pp.369-377, 2004. ,
Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae, BMC Microbiology, vol.16, pp.1-11, 2016. ,
Population Dynamics of Antibiotic Treatment: a Mathematical Model and Hypotheses for Time-Kill and Continuous-Culture Experiments, Antimicrobial Agents and Chemotherapy, vol.54, pp.3414-3426, 2010. ,
Time-kill kinetics of antibiotics active against rapidly growing mycobacteria, In: Journal of Antimicrobial Chemotherapy, vol.70, pp.811-817, 2015. ,
Selection of Resistant Bacteria at Very Low Antibiotic Concentrations, PLoS Pathogens, vol.7, pp.1-9, 2011. ,
The Rate of Killing of Escherichia coli by P-Lactam Antibiotics Is Strictly Proportional to the Rate of Bacterial Growth, Journal of General Microbiology, vol.132, pp.1297-1304, 1986. ,
Suppressive drug combinations and their potential to combat antibiotic resistance, The Journal of Antibiotics, vol.70, pp.1033-1042, 2017. ,
Multidrug evolutionary strategies to reverse antibiotic resistance, Science, vol.351, pp.1-10, 2016. ,
Emergence of robust growth laws from optimal regulation of ribosome synthesis, In: Molecular Systems Biology, vol.10, pp.747-747, 2014. ,
Bacterial Temporal Dynamics Enable Optimal Design of Antibiotic Treatment, PLOS Computational Biology, vol.11, pp.1-22, 2015. ,
Predicting the dynamics of bacterial growth inhibition by ribosometargeting antibiotics, Physical Biology, vol.14, pp.1-17, 2017. ,
Building a morbidostat: an automated continuousculture device for studying bacterial drug resistance under dynamically sustained drug inhibition, Nature Protocols, vol.8, issue.3, pp.555-567, 2013. ,
Flow distribution in parallel microfluidic networks and its effect on concentration gradient, Biomicrofluidics 9, vol.5, pp.1-13, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01246210
SOS Repair Hypothesis: Phenomenology of an Inducible DNA Repair Which is Accompanied by Mutagenesis". In: Molecular Mechanisms for Repair of DNA, Basic Life Sciences, pp.355-367, 1975. ,
SOS, the formidable strategy of bacteria against aggressions, FEMS Microbiology Reviews, vol.38, pp.1126-1145, 2014. ,
URL : https://hal.archives-ouvertes.fr/pasteur-01423593
Reconstitution of an SOS Response Pathway: Derepression of Transcription in Response to DNA Breaks, Cell 95, vol.7, pp.975-979, 1998. ,
After 30 Years of Study, the Bacterial SOS Response Still Surprises Us, PLOS Biology, vol.3, pp.1-3, 2005. ,
Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli, In: Genetics, vol.158, pp.41-64, 2001. ,
RecFOR proteins are essential for Pol V-mediated translesion synthesis and mutagenesis, The EMBO Journal, vol.25, pp.5754-5763, 2006. ,
Induction of the SOS response and mutations by reactive oxygen-generating compounds in various Escherichia coli mutants defective in the mutM, mutY or soxRS loci, Mutagenesis 9, vol.3, pp.245-251, 1994. ,
An SOS Response Induced by High Pressure in Escherichia coli, Journal of Bacteriology, vol.186, pp.6133-6141, 2004. ,
SOS response and its regulation on the fluoroquinolone resistance, Annals of Translational Medicine, vol.3, pp.1-17, 2015. ,
SOS Reponse induction by Beta-Lactams and Bacterial Defense Against Antibiotic Lethality, Science 305, vol.5690, pp.1629-1631, 2004. ,
Modulation of Salmonella gene expression by subinhibitory concentrations of quinolones, The Journal of Antibiotics, vol.64, pp.73-78, 2011. ,
Regulation of cell division in Escherichia coli: SOS induction and cellular location of the sulA protein, a key to lon-associated filamentation and death, In: Journal of Bacteriology, vol.158, pp.551-561, 1984. ,
The dinB Gene Encodes a Novel E. coli DNA Polymerase, Molecular Cell, vol.4, pp.281-286, 1999. ,
Defining the Pseudomonas aeruginosa SOS Response and Its Role in the Global Response to the Antibiotic Ciprofloxacin, Journal of Bacteriology, vol.188, pp.7101-7110, 2006. ,
The SOS response promotes qnrB quinolone-resistance determinant expression, EMBO Reports, vol.10, pp.929-933, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00533078
SOS involvement in stress-inducible biofilm formation, In: Biofouling, vol.26, pp.603-611, 2010. ,
Understanding biofilm resistance to antibacterial agents, Nature Reviews. Drug Discovery, vol.2, issue.2, pp.114-122, 2003. ,
SOS response promotes horizontal dissemination of antibiotic resistance genes, Nature, vol.427, pp.72-74, 2004. ,
RecA Inhibitors Potentiate Antibiotic Activity and Block Evolution of Antibiotic Resistance, Cell Chemical Biology, vol.23, pp.381-391, 2016. ,
Precise Temporal Modulation in the Response of the SOS DNA Repair Network in Individual Bacteria, PLoS Biology, vol.3, pp.1-8, 2005. ,
Stochastic Analysis of the SOS Response in Escherichia coli, PLoS ONE, vol.4, pp.1-7, 2009. ,
Subinhibitory concentrations of ciprofloxacin induce SOS response and mutations of antibiotic resistance in bacteria, Annals of Microbiology, vol.60, pp.511-517, 2010. ,
Culture Medium for Enterobacteria, Journal of Bacteriology, vol.119, pp.736-747, 1974. ,
One-Step Cloning and Chromosomal Integration of DNA, ACS Synthetic Biology, vol.2, issue.9, pp.537-541, 2013. ,
Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ, Proceedings of the National Academy of Sciences, vol.100, pp.7889-7894, 2003. ,
Measurement of SOS expression in individual Escherichia coli K-12 cells using fluorescence microscopy, Molecular Microbiology, vol.53, pp.1343-1357, 2004. ,
, DNA Repair and Mutagenesis, 1995.
The RpoS-mediated general stress response in Escherichia coli, Annual Review of Microbiology, vol.65, pp.189-213, 2011. ,
TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats, Cell Reports, vol.22, pp.2146-2159, 2018. ,
URL : https://hal.archives-ouvertes.fr/hal-01727334
Tracking the Evolution of Transiently Transfected Individual Cells in a Microfluidic Platform, Scientific Reports, vol.8, pp.1-9, 2018. ,
Mapping Structure and Biological Functions within Mesenchymal Bodies using Microfluidics, p.bioRxiv, 2019. ,
Physics of Cancer: The Impact of Heterogeneity, Annual Review of Condensed Matter Physics, vol.3, issue.1, pp.363-382, 2012. ,
Acceleration of Emergence of Bacterial Antibiotic Resistance in Connected Microenvironments, Science, vol.333, pp.1764-1767, 2011. ,
, MARKETS AND MARKETS. Microfluidics Market worth 27.91 Billion USD by 2023, 2018.
Open-source, community-driven microfluidics with Metafluidics, Nature Biotechnology, vol.35, pp.523-529, 2017. ,
Antibiotics in agriculture: When is it time to close the barn door?, In: Proceedings of the National Academy of Sciences, vol.99, issue.9, pp.5752-5754, 2002. ,
Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria, Proceedings of the National Academy of Sciences, vol.99, pp.6434-6439, 2002. ,
Global Change and the Challenges of Sustainably Feeding a Growing Planet, 2016. ,
The Impacts of Dietary Change on Greenhouse Gas Emissions, Land Use, Water Use, and Health: A Systematic Review, PLOS ONE, vol.11, pp.1-16, 2016. ,