Action antioxydante et antimicrobienne de composés phénoliques dans des milieux modèles et des émulsions riches en lipides insaturés

Abstract : Phenolic compounds appear to be good candidates for ensuring the quality and safety of several perishable products like ready-to-eat food. Widely found in plants and byproducts from agro-industries, they offer a potential solution to limit the oxidation of omega-3 polyunsaturated fatty acids (e.g. DHA and EPA) and the growth of foodborne pathogens such as Listeria monocytogenes.The aim of this PhD is to evaluate dual antioxidant and antimicrobial activity in complex food media and to better understand the associated mechanisms of action.First experiments carried out with a series of phenolic compounds in simple model media confirmed this dual efficiency.Interesting structure/activity relationships were highlighted and some mechanisms of action were decrypted, involving parameters like number and chemical environment of phenolic groups, logP, dissociated/undissociated forms of phenolic acids. The performances of three selected phenolic compounds, i.e. eugenol, ferulic acid and α-tocopherol (added alone or as a mixture), were evaluated in more realistic complex food media: o/w emulsions composed of fish oil, aqueous phase and whey proteins or Tween 80 as emulsifiers. Ferulic acid shows no antioxidant activity but can inhibit the development of L. monocytogenes. In contrast, eugenol and α-tocopherol are good antioxidants but not antimicrobials in emulsions formulated with whey proteins. Mechanisms of action are proposed to explain these behaviors.
Complete list of metadatas

Cited literature [353 references]  Display  Hide  Download

https://tel.archives-ouvertes.fr/tel-02139084
Contributor : Abes Star <>
Submitted on : Friday, May 24, 2019 - 1:45:07 PM
Last modification on : Saturday, May 25, 2019 - 1:35:27 AM

File

70942_PERNIN_2018_archivage.pd...
Version validated by the jury (STAR)

Identifiers

  • HAL Id : tel-02139084, version 1

Collections

Citation

Aurélia Pernin. Action antioxydante et antimicrobienne de composés phénoliques dans des milieux modèles et des émulsions riches en lipides insaturés. Génie des procédés. Université Paris-Saclay, 2018. Français. ⟨NNT : 2018SACLA033⟩. ⟨tel-02139084⟩

Share

Metrics

Record views

159

Files downloads

94