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C. , S. , and S. A. Hospital, The data were extracted from the PsyDEV study (Familial and genetic study of developmental features in psychiatric disorder, promoted by Inserm), a data collection concerning developmental features in psychiatric disorders or from AUSZ (AutismSchizophrenia Continuum: research of clinical, biological and neuroimaging phenotypic markers, promoted by Sainte-Anne Hospital). For the current study, we selected participants aged between 16-30 years old with available DDSQ and/or Autism Diagnosis Interview (ADI-R) (Lord et al., 1994). Mean age and sex ratio were comparable in both samples. In the ASD subgroup, ADI-R was available for all subjects; 44 self-administrated DDSQ version (DDSQs) and 36 parents version (DDSQp) were available (for 31 subjects, both versions were completed), MATERIAL AND METHODS 2.1. PARTICIPANTS AND EVALUATION The total sample consisted in 128 subjects including 62 patients with SCZ (DSM-IV criteria) and 66 with ASD (HFA or Asperger syndrome)

, All subjects were examined with the Diagnostic Interview for Genetic Studies (DIGS 3.0, Nurnberger, 1994.

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, Caractère stéréotypé ou répétitif des mouvements, de l'utilisation des objets ou du langage (par ex. stéréotypés motrices simples, activités d'alignement des jouets ou des rotation des objets, écholalie

C. Intolérance-au, adhésion inflexible à des routines ou à des modes comportements verbaux ou non verbaux ritualisés (par ex. détresse extrême provoquée par des changements mineurs, difficultés à gérer des transitions, modes de pensée rigide, ritualisation des formules de salutation

, Intérêts extrêmement restreints et fixes, anormaux soit dans leur intensité

, Hyper ou hyporéactivité aux stimulations sensorielles ou intérêt inhabituel pour les aspects sensoriels de l'environnement (par ex. indifférence apparente à la douleur ou à la température, réactions négatives à des sons ou à des textures spécifiques, action de flairer ou de toucher excessivement les objets

C. , Les symptômes doivent être présent dès les étapes précoces du développement D. Les symptômes occasionnent un retentissement cliniquement significatif en termes de fonctionnement actuel social

E. , Ces troubles ne sont pas mieux expliqués par un handicap intellectuel ou un retard global du développement

C. P. Renseignements-:-en and . ????????????????????????,

, Age à l'entrée en collège ou équivalent : ?????????????????

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, Détermination d'un quotient intellectuel ? si oui à quel âge et résultat: ??????????????????????????

, Votre mère a t'elle eu des complications pendant sa grossesse ? (NB: Hypertension, diabète, infection, traumatisme, préciser si possible une éventuelle prise de médicaments ou de tabac/alcool/ou autres toxiques) ???????????????????????

. .. ??????????????????????????,

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. .. ??????????????????????????, Avez-vous eu des problèmes médicaux ou traumatiques durant vos premières années (précisez l'âge)

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;. ?. Poids-de-naissance,

:. ?. ?-taille-de-naissance,

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. Y-a-t-il-déjà-eu-une and . .. ???????????????????????,

?. .. , Vous a-t-on déjà fait un caryotype ? si oui, pourquoi, résultat ?

, Fille : Age puberté : Garçon : 2014 Continuum autisme-schizophrénie : données neuro-cognitives 7ème Journée Internationale des Pathologies Emergentes de l'Adolescent et du Jeune Adulte (JIPEJAAD), vol.18

G. Martinez, C. Mam-lam-fook, C. Alexandre, N. Bendjemaa, R. Gaillard et al., Autism -schizophrenia continuum hypothesis in the light of social cognition, Schizophrenia International Research Society 5th Biennal Conference, 2016.

G. Martinez, C. Mam-lam-fook, P. Garel, A. I. Krebs, and M. O. , Social cognition anomalies in autism and schizophrenia : a direct comparison using the French version of MASC test, Schizophrenia International Research Society 4th Biennal Conference, 2014.

C. Mam-lam-fook, G. Martinez, C. Alexandre, Z. Prost, R. Gaillard et al., Evaluation de la mémoire autobiographique et du soi dans la schizophrénie et les troubles envahissants du développement : étude pilote Congrès de l'Encéphale, 2104.

G. Martinez, O. Gay, Y. Morvan, I. Amado, N. Bendjemaa et al., Continuum autism-schizophrénie ?, Repérage des symptômes autistiques dans la trajectoire précoce des patients souffrant de schizophrénie Congrès de l'Encéphale, 2013.

, Direction de thèses et mémoires

, Direction de thèse de médecine Evaluation du risque de transition psychotique chez les jeunes adultes avec trouble du spectre de l'autisme. Benhammadi M

, Direction de thèse de médecine Théorie de l'esprit dans la schizophrénie et les troubles du spectre de l'autisme : similitudes et différences. Mosconi E

, Direction de mémoire scientifique de DES Théorie de l'esprit dans la schizophrénie et les troubles du spectre de l'autisme : comparaison a l'âge adulte, 2016.

M. Gilles, , 2017.

, Laboratoire Physiopathologie des Maladies Psychiatriques : développement et vulnérabilité