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Un outil diagnostique consensuel de la dépression pour servir de nombreux pays : un défi !

Abstract : Depression is a common reason for consultation in general practice. Its variability makes its diagnosis difficult. An effective, reliable and ergonomic diagnostic tool would be an aid to research in general practice. The aim of this study was to find a consensual tool between general practitioners (GPs) and psychiatrists in several European countries.Methods: A systematic literature review was undertaken to find validated tools in general practice against the psychiatrist. A consensus according to a RAM (RAND/UCLA Appropriateness Method) has selected one. It has been translated according to a procedure guaranteeing the stability and the ecology in general practice. A validation protocol has been produced to ensure the retention of psychometric qualities. The French external validation study was carried out.Results: Seven tools were extracted: CESD-R, GDS 5-15-30 items, PSC-51, HADS, HSCL-25.Psychometric effectiveness data (Se, Sp, VPP, VPN) were collected. The HSCL-25 has been selected for its high combined qualities of effectiveness, reliability and ergonomics. It has been translated into 9 languages relating to 3 linguistic groups: Greek, Romance and Slavic languages. The French Validation Study has proven that the French form of HSCL-25 (F-HSCL-25) has high diagnostic performance (Se 59.4%, Sp 91.4%, VPP 69.8%, and VPN 86.9%) adapted to research in general practice.Implication: HSCL-25 is a valid and effective tool for diagnosing depression in primary care. They could increase the diagnostic performance of GPs and foster collaborative research.
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Patrice Nabbe. Un outil diagnostique consensuel de la dépression pour servir de nombreux pays : un défi !. Human health and pathology. Université de Bretagne occidentale - Brest; Universiteit Antwerpen, 2018. English. ⟨NNT : 2018BRES0035⟩. ⟨tel-02076863⟩

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