J. Ripoll, L. Urban, M. Staudt, F. Lopez­lauri, L. Bidel et al., Day-length affects the dynamics of leaf expansion and cellular development in Arabidopsis thaliana partially through loral transition timing, Annals of Botany, vol.99, pp.703-711, 2007.

S. J. Cookson, M. Van-lijsebettens, and C. Granier, Correlations between leaf growth variables suggest intrinsic and early controls of leaf size in Arabidopsis thaliana, Plant, Cell and Environment, vol.28, pp.1355-1366, 2005.

A. Coupel-ledru, É. Lebon, and C. A. , Genetic variation in a grapevine progeny (Vitis vinifera L. cvs Grenache × Syrah) reveals inconsistencies between maintenance of daytime leaf water potential and response of transpiration rate under drought, Journal of Experimental Botany, vol.65, pp.6205-6218, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01054469

A. Dambreville, M. Griolet, and G. Rolland, Phenotyping oilseed rape growth-related traits and their responses to water deicit: the disturbing pot size effect, Functional Plant Biology, vol.44, pp.35-45, 2017.

D. Veylder, L. Larkin, J. C. Schnittger, and A. , Molecular control and function of endoreplication in development and physiology, Trends in Plant Sciences, vol.16, pp.624-634, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00638845

P. M. Donnelly, D. Bonetta, H. Tsukaya, R. E. Dengler, and N. G. Dengler, Cell cycling and cell enlargement in developing leaves of Arabidopsis, Developmental Biology, vol.215, pp.407-419, 1999.

B. A. Edgar, N. Zielke, and C. Gutierrez, Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth, Nature Reviews. Molecular Cell Biology, vol.15, pp.197-210, 2014.

A. Ferjani, G. Horiguchi, S. Yano, and H. Tsukaya, Analysis of leaf development in fugu mutants of Arabidopsis reveals three compensation modes that modulate cell expansion in determinate organs, Plant Physiology, vol.144, pp.988-999, 2007.

A. J. Fleming, Cell cycle control during leaf development, Cell cycle control and plant development, vol.32, pp.203-226, 2007.

P. J. Flood, W. Kruijer, and S. K. Schnabel, Phenomics for photosynthesis, growth and relectance in Arabidopsis thaliana reveals circadian and long-term luctuations in heritability, Plant Methods, vol.12, p.14, 2016.

A. Gázquez and G. Beemster, What determines organ size differences between species? A meta-analysis of the cellular basis, New Phytologist, vol.215, pp.299-308, 2017.

N. Gonzalez, H. Vanhaeren, and D. Inzé, Leaf size control: complex coordination of cell division and expansion, Trends in Plant Sciences, vol.17, pp.332-340, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01606375

C. Granier and F. Tardieu, Spatial and temporal analyses of expansion and cell cyle in sunlower leaves. A common pattern of development for all zones of a leaf and different leaves of a plant, Plant Physiology, vol.116, pp.991-1001, 1998.

C. Granier, O. Turc, and F. Tardieu, Co-ordination of cell division and tissue expansion in sunlower, tobacco and pea leaves. Dependence or independence of both processes, Journal of Plant Growth Regulation, vol.19, pp.45-54, 2000.

C. Granier, L. Aguirrezabal, and K. Chenu, PHENOPSIS, an automated platform for reproducible phenotyping of plant responses to soil water deicit in Arabidopsis thaliana permitted the identiication of an accession with low sensitivity to soil water deicit, New Phytologist, vol.169, pp.623-635, 2006.

D. Hareven, T. Gutinger, A. Parnis, Y. Eshed, and E. Lifschitz, The making of a compound leaf: genetic manipulation of leaf architecture in tomato, Cell, vol.84, pp.735-744, 1996.

A. Hemerly, E. Jda, and C. Bergounioux, Dominant negative mutants of the Cdc2 kinase uncouple cell division from iterative plant development, EMBO Journal, vol.14, pp.3925-3936, 1995.

T. Hisanaga, K. Kawade, and H. Tsukaya, Compensation: a key to clarifying the organ-level regulation of lateral organ size in plants, Journal of Experimental Botany, vol.66, pp.1055-1063, 2015.

G. Horiguchi, A. Ferjani, U. Fujikura, and H. Tsukaya, Coordination of cell proliferation and cell expansion in the control of leaf size in Arabidopsis thaliana, Journal of Plant Research, vol.119, pp.37-42, 2006.

C. Hunter, H. Sun, and R. S. Poethig, The Arabidopsis heterochronic gene ZIPPY is an ARGONAUTE family member, Current Biology, vol.13, pp.1734-1739, 2003.

P. John and R. Qi, Cell division and endoreduplication: doubtful engines of vegetative growth, Trends in Plant Sciences, vol.13, pp.121-127, 2008.

D. R. Kaplan, Comparative developmental evaluation of the morphology of unifacial leaves in the monocotyledons, Planzengeschichte und Planzengeographie, vol.95, pp.1-105, 1975.

D. R. Kaplan and W. Hagemann, The relationship of cell and organism in vascular plants: are cells the building-blocks of plant form, Bioscience, vol.4, pp.693-703, 1991.

Y. Katagiri, J. Hasegawa, U. Fujikura, R. Hoshino, S. Matsunaga et al., The coordination of ploidy and cell size differs between cell layers in leaves, Development, vol.143, pp.1120-1125, 2016.

H. C. Lee, D. W. Chiou, W. H. Chen, A. H. Markhart, Y. H. Chen et al., Dynamics of cell growth and endoreduplication during orchid lower development, Plant Science, vol.166, pp.659-667, 2004.

M. Lièvre, C. Granier, and Y. Guédon, Identifying developmental phases in Arabidopsis thaliana rosette using integrative segmentation models, New Phytologist, vol.210, pp.1466-1478, 2016.

C. Massonnet, S. Tisné, and A. Radziejwoski, New insights into the control of endoreduplication: endoreduplication is driven by organ growth in Arabidopsis leaves, Plant Physiology, vol.157, pp.2044-2055, 2011.

E. Mathieu-rivet, F. Gevaudant, and A. Sicard, Functional analysis of the anaphase promoting complex activator CCS52A highlights the crucial role of endo-reduplication for fruit growth in tomato, The Plant Journal, vol.62, pp.727-741, 2010.
URL : https://hal.archives-ouvertes.fr/hal-01848369

J. E. Melaragno, B. Mehrotra, and A. W. Coleman, Relationship between endopolyploidy and cell size in epidermal tissue of Arabidopsis, The Plant Cell, vol.5, pp.1661-1680, 1993.

K. A. Nagel, A. Putz, and F. Gilmer, GROWSCREEN-Rhizo is a novel phenotyping robot enabling simultaneous measurements of root and shoot growth for plants grown in soil-illed rhizotrons, Functional Plant Biology, vol.39, pp.891-904, 2012.

H. Nelissen, N. Gonzalez, and D. Inzé, Leaf growth in dicots and monocots: so different yet so alike, Current Opinion in Plant Biology, vol.33, pp.72-76, 2016.
DOI : 10.1016/j.pbi.2016.06.009
URL : https://hal.archives-ouvertes.fr/hal-01602883

M. Pavicic, K. Mouhu, F. Wang, M. Bilicka, E. Chovancek et al., Genomic and phenomic screens for lower related RING type ubiquitin E3 ligases in Arabidopsis, Frontiers in Plant Science, vol.8, p.416, 2017.
DOI : 10.3389/fpls.2017.00416
URL : https://www.frontiersin.org/articles/10.3389/fpls.2017.00416/pdf

K. A. Pyke, J. L. Marisson, and R. M. Leech, Temporal and spatial development of the cells of the expanding irst leaf of Arabidopsis thaliana (L.) Heynh, Journal of Experimental Botany, vol.42, pp.1407-1416, 1991.

R. Development-core and . Team, R: a language and environment for statistical computing, R Foundation for Statistical Computing, 2014.

R. E. Rodriguez, J. M. Debernardi, and J. F. Palatnik, Morphogenesis of simple leaves: regulation of leaf size and shape, Wiley Interdisciplinary Reviews: Developmental Biology, vol.3, pp.41-57, 2014.

A. Roeder, V. Chickarmane, A. Cunha, B. Obara, B. S. Manjunath et al., Variability in the control of cell division underlies sepal epidermal patterning in Arabidopsis thaliana, PLoS Biology, vol.8, p.1000367, 2010.

B. Rymen, F. Fiorani, F. Kartal, K. Vandepoele, D. Inzé et al., Cold nights impair leaf growth and cell cycle progression in maize through transcriptional changes of cell cycle genes, Plant Physiology, vol.143, pp.1429-1438, 2007.

R. Sablowski, Coordination of plant cell growth and division: collective control or mutual agreement?, Current Opinion in Plant Biology, vol.34, pp.54-60, 2016.

W. Sadok, P. H. Naudin, B. Boussuge, B. Muller, C. Welcker et al., Leaf growth rate per unit thermal time follows QTL-dependent daily patterns in hundreds of maize lines under naturally luctuating conditions, Plant, Cell and Environment, vol.30, pp.135-146, 2007.

R. Sattler and R. Rutishauser, Partial homology of pinnate leaves and shoots: orientation of lealet inception, Planzengeschichte und Planzengeographie, vol.114, pp.61-79, 1992.

D. R. Scholes and K. N. Paige, Plasticity in ploidy: a generalized response to stress, Trends in Plant Science, vol.20, pp.165-175, 2015.

A. Skirycz, K. Vandenbroucke, and P. Clauw, Survival and growth of Arabidopsis plants given limited water are not equal, Nature Biotechnology, vol.29, pp.212-214, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01607043

K. Sugimoto-shirasu and K. Roberts, Big it up': endoreduplication and cell-size control in plants, Current Opinion in Plant Biology, vol.6, pp.544-553, 2003.

F. Tardieu, M. Reymond, H. Hamard, C. Granier, and B. Muller, Spatial distributions of expansion rate, cell division rate and cell size in maize leaves: a synthesis of the effects of soil water status, evaporative demand and temperature, Journal of Experimental Botany, vol.51, pp.1505-1514, 2000.

M. W. Ter-steege, F. M. Den-ouden, H. Lambers, P. Stam, and A. Peeters, Genetic and physiological architecture of early vigor in Aegilops tauschii, the D-genome donor of hexaploid wheat. A quantitative trait loci analysis, Plant Physiology, vol.139, pp.1078-1094, 2005.

S. Tisné, M. Reymond, D. Vile, J. Fabre, M. Dauzat et al., Combined genetic and modeling approaches reveal that epidermal cell area and number in leaves are controlled by leaf and plant developmental processes in Arabidopsis, Plant Physiology, vol.148, pp.1117-1127, 2008.

S. Tisné, F. Barbier, and C. Granier, The ERECTA gene controls spatial and temporal patterns of epidermal cell number and size in successive developing leaves of Arabidopsis thaliana, Annals of Botany, vol.108, pp.159-168, 2011.

T. Tojo, K. Tsuda, T. Yoshizumi, A. Ikeda, J. Yamaguchi et al., Arabidopsis MBF1s control leaf cell cycle and its expansion, Plant and Cell Physiology, vol.50, pp.254-264, 2008.

H. Tsukaya, The leaf index: heteroblasty, natural variation, and the genetic control of polar processes of leaf expansion, Plant and Cell Physiology, vol.43, pp.372-378, 2002.

H. Tsukaya, Does ploidy level directly control cell size? Counterevidence from Arabidopsis genetics, PLoS One, vol.8, p.83729, 2013.

H. Tsukaya, Comparative leaf development in angiosperms, Current Opinion in Plant Biology, vol.17, pp.103-109, 2014.

T. Usami, G. Horiguchi, S. Yano, and H. Tsukaya, The more and smaller cells mutants of Arabidopsis thaliana identify novel roles for SQUAMOSA PROMOTER BINDING PROTEIN-LIKE genes in the control of heteroblasty, Development, vol.136, pp.955-964, 2009.

H. Vanhaeren, D. Inzé, and N. Gonzalez, Plant growth beyond limits, Trends in Plant Science, vol.21, p.102, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01608650

N. Wuyts, C. Massonnet, M. Dauzat, and C. Granier, Structural assessment of the impact of environmental constraints on Arabidopsis leaf growth: a 3D approach, Plant, Cell and Environment, vol.35, pp.1631-1646, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01268201

G. Zotz, K. Wilhelm, and A. Becker, Heteroblasty -a review, The Botanical Review, vol.77, pp.109-151, 2011.

. Inra-lepse, 2 place Viala ,34060 Montpellier cedex, France myriam.dauzat@supagro.inra.fr

S. Optimalog and . De-la-fontaine-de-mié, 37540 Saint Cyr sur Loire, France 3 adresse actuelle : CEFE, 1919, Route de Mende, Germany imagerie PAM (Imaging PAM chlorophyll fluorometer, vol.34090

, Merci à Yves Primault (www.bionef.fr) pour la société Walz pour l'application Fluorescence développée en lien avec Optimalog, ainsi que la société AM Froid pour la partie Climatisation

. Merci-À-florent, . Anthony, . Gaëlle, . Crispulo, and F. Nicolas, Nathalie qui ont très largement contribué aux améliorations décrites dans cet article

, Les évolutions de PHENOPSIS décrites dans cet article ont été réalisées grâce au soutien du projet FP7-EPPN (European Plant Phenotyping Network

. Durant, Justine Bresson était soutenue par le ministère Français de l'Enseignement Supérieur et de la Recherche, François Vasseur était soutenu par un contrat CIFRE (cofinancé par l'ANRT, ministère Français de la Recherche et la société BAYER Crop Science

, PHENOPSIS fait partie de 'Montpellier Plant Phenotyping Platforms' (M3P

J. Bresson, The PGPR strain Phyllobacterium brassicacearum STM196 induces a reproductive delay and physiological changes that result in improved drought tolerance in Arabidopsis, New Phytol, vol.200, pp.558-569, 2013.

J. Bresson, F. Vasseur, M. Dauzat, G. Koch, C. Granier et al., Quantifying spatial heterogeneity of wholeplant chlorophyll fluorescence during growth and in response to water stress, p.23, 2015.

A. Dambreville, M. Giolet, G. Rolland, M. Dauzat, A. Bédiée et al., Phenotyping oilseed rape growth-related traits and their responses to water defici t: the disturbing pot size effect, Funct Plant Biol, 2016.

E. Ashby, Studies in the morphogenesis of leaves. 2. The area, cell size and cell number of leaves of Ipomoea in relation to their position on the shoot, New Phytol, vol.47, issue.2, pp.177-195, 1948.

N. Baldazzi, N. Bertin, and M. Ge?nardge?nard, A model of fruit growth integrating cell division and expansion processes, Acta Hortic, vol.957, pp.191-196, 2012.

V. Boudolf, K. Vlieghe, G. T. Beemster, Z. Magyar, J. A. Torres-acosta et al., The plant-specific cyclin-dependent kinase CDKB1;1 and transcription factor E2Fa-DPa control the balance of mitotically dividing and endoreduplicating cells in Arabidopsis, Plant Cell, vol.16, issue.10, pp.2683-2692, 2004.

M. Bourdon, O. Coriton, J. Pirrello, C. Cheniclet, S. C. Brown et al., In planta quantification of endoreduplication using fluorescent in situ hybridization (FISH), Plant J, vol.66, issue.6, pp.1089-1099, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00855934

C. Cheniclet, W. Y. Rong, M. Causse, N. Frangne, L. Bolling et al., Cell expansion and endoreduplication show a large genetic variability in pericarp and contribute strongly to tomato fruit growth, Plant Physiol, vol.139, 1984.

S. J. Cookson, A. Radziejwoski, and C. Granier, Cell and leaf size plasticity in Arabidopsis: what is the role of endoreduplication?, Plant Cell Environ, vol.29, issue.7, pp.1273-1283, 2006.

S. J. Cookson, K. Chenu, and C. Granier, Day length affects the dynamics of leaf expansion and cellular development in Arabidopsis thaliana partially through floral transition timing, Ann. Bot, vol.99, issue.4, pp.703-711, 2007.

D. Veylder, L. Larkin, J. C. Schnittger, and A. , Molecular control and function of endoreplication in development and physiology, Trends Plant Sci, vol.16, issue.11, pp.624-634, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00638845

W. Dewitte, S. Scofield, A. A. Alcasabas, S. C. Maughan, M. Menges et al., Arabidopsis CYCD3 D-type cyclins link cell proliferation and endocycles and are rate-limiting for cytokinin responses, Proc. Natl. Acad. Sci. U.S.A, vol.104, issue.36, pp.14537-14542, 2007.

P. M. Donnelly, D. Bonetta, H. Tsukaya, R. E. Dengler, and N. G. Dengler, Cell cycling and cell enlargement in developing leaves of Arabidopsis, Dev. Biol, vol.215, issue.2, pp.407-419, 1999.

J. Fanwoua, . De, P. H. Visser, E. Heuvelink, X. Yin et al., A dynamic model of tomato fruit growth integrating cell division, cell growth and endoreduplication. Func. Plant Biol, vol.40, pp.1098-1114, 2013.

G. Gillaspy, H. Ben-david, and W. Gruissem, Fruits: a developmental perspective, Plant Cell, vol.5, issue.10, pp.1439-1451, 1993.

C. Granier and F. Tardieu, Spatial and temporal analyses of expansion and cell cycle in sunflower leaves. A common pattern of development for all zones of a leaf and different leaves of a plant, Plant Physiol, vol.116, issue.3, pp.991-1001, 1998.

P. C. John and R. Qi, Cell division and endoreduplication: doubtful engines of vegetative growth, Trends Plant Sci, vol.13, issue.3, pp.121-127, 2008.

J. E. Melaragno, B. Mehrotra, C. , and A. W. , Relationship between endopolyploidy and cell size in epidermal tissue of Arabidopsis, Plant Cell, vol.5, issue.11, pp.1661-1668, 1993.

M. Nafati, C. Cheniclet, M. Hernould, P. T. Do, A. R. Fernie et al., The specific overexpression of a cyclin-dependent kinase inhibitor in tomato fruit mesocarp cells uncouples endoreduplication and cell growth, Plant J, vol.65, issue.4, pp.543-556, 2011.

A. H. Roeder, V. Chickarmane, A. Cunha, B. Obara, B. S. Manjunath et al., Variability in the control of cell division underlies sepal epidermal patterning in Arabidopsis thaliana, PLoS Biol, vol.8, issue.5, 2010.

D. R. Scholes, P. , and K. N. , Plasticity in ploidy: a generalized response to stress, Trends Plant Sci, vol.20, pp.165-175, 2015.

K. Sugimoto-shirasu and K. Roberts, Big it up": endoreduplication and cell-size control in plants, Cur. Op. Plant Biol, vol.6, pp.544-553, 2003.

T. Tisne?, S. Barbier, F. Granier, and C. , The ERECTA gene controls spatial and temporal patterns of epidermal cell number and size in successive developing leaves of Arabidopsis thaliana, Ann. Bot, vol.108, issue.1, pp.159-168, 2011.
URL : https://hal.archives-ouvertes.fr/hal-00999882

T. Tojo, K. Tsuda, T. Yoshizumi, A. Ikeda, J. Yamaguchi et al., Arabidopsis MBF1s control leaf cell cycle and its expansion, Plant Cell Physiol, vol.50, issue.2, pp.254-264, 2009.

K. Vlieghe, V. Boudolf, G. T. Beemster, S. Maes, Z. Magyar et al., The DP-E2F-like gene DEL1 controls the endocycle in Arabidopsis thaliana, Curr. Biol, vol.15, issue.1, pp.59-63, 2005.