Treg) est analysée sur des critères phénotypiques (CD39, CD73, PD-1, Tim-3) et fonctionnels (IFN-?, Chacune de populations sélectionnées ,
, Chacune de populations sélectionnées (LB, NK, T??) est analysée sur des critères phénotypiques (CD39, CD73, PD-1) et fonctionnels (IFN-?, CD107a)
, Chacune de populations sélectionnées (DC, monocytes, MDSCs) est analysée sur des critères phénotypiques (CD39, CD73) et fonctionnels
, Stratégie d'analyse des populations immunitaires Humaines
, MDSCs) est analysée sur des critères phénotypiques (CD39, CD73, PD-1, Tim-3) et fonctionnels (IL-2, IFN-?, CD107a)
, Publications Internationales à comité de lecture
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21 Promotes the Development of a CD73-Positive V?9V?2 T Cell Regulatory Population ,
, Oncoimmunology, vol.7, issue.1, p.1379642, 2017.
, Microcavity Formation and Lesion Volume After Severe Spinal Cord Injury ». Noristani, Harun Najib, Laetitia They, et Florence Evelyne Perrin, « C57BL/6 and Swiss Webster Mice Display Differences in Mobility, Gliosis, vol.12, 2018.
, Strenghtening the immunomodulatory effects of anti-tumor monoclonal antibody using an anti-immune checkpoint inhibitor in melanoma. 2018: Potentiation of immunomodulatory effects of an anti-tumor monoclonal antibody. Présentation aux Journées des Etudiants en Thèse de l'IRCM (JET) 2016: The immunomodulatory effects of an anti-tumor monoclonal antibody in melanoma. 2018: Potentiation of immunomodulatory effects of an anti-tumor monoclonal antibody, Présentation aux retraites du Labex MAbImprove : 2016: Strenghtening the immunomodulatory effects of anti-tumor monoclonal antibody: Study of potentiating effects of combined therapies and analysis of the mechanisms involved, 2017.
, Présentation à la Journée de l'Ecole Doctorale CBS2 (CBS2 Day) 2018: Potentation of immunomodulatory effects of an anti-tumor monoclonal antibody
, 2016: Characterization of long-term protective immunity after anti-tumor-based immunotherapy in melanoma
, Présentation à la 12 ème Journée Cancéropôle Grand Sud-Ouest (GSO) 2016: PD-1 blockade potentiates immunomodulatory functions of a tumor antigen targeting monoclonal antibody, Prix du meilleur poster, Fondation SILAB Jean-Paufique
, Participation à l'organisation des journées scientifiques de l'ED CBS2 des éditions 2016, 2017.
, Bénévole et participante (table ronde) au 17 ème colloque de Femmes & Sciences édition, 2017.
« LongLasting Antitumor Protection by Anti-CD20 Antibody through Cellular Immune Response, Blood, vol.116, issue.6, p.92634, 2010. ,
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« The Bcl-2 Apoptotic Switch in Cancer Development and Therapy, Oncogene, vol.26, issue.9, p.132437, 2007. ,
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« Tumor Antigen-Specific CD8 T Cells Infiltrating the Tumor Express High Levels of PD-1 and Are Functionally Impaired, Blood, vol.114, issue.8, p.153744, 2009. ,
« TGF-Beta Signaling in Cancer, Trends in Cell Biology, vol.11, issue.11, pp.44-51, 2001. ,
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, , vol.30
« High Expression of Ecto-Nucleotidases CD39 and CD73 in Human Endometrial Tumors ». Research article. Mediators of Inflammation, 2014. ,
« IPH-2101, a Fully Human Anti-NK-Cell Inhibitory Receptor MAb for the Potential Treatment of Hematological Cancers, Current Opinion in Molecular Therapeutics, vol.12, issue.6, p.72433, 2010. ,
, et John Stagg. 2013. « Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 MAbs
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« Phase II study of vemurafenib followed by ipilimumab in patients with previously untreated BRAF-mutated metastatic melanoma », Journal for ImmunoTherapy of Cancer, vol.4, issue.1, p.44, 2016. ,
« Maturation and Activation of Dendritic Cells Induced by Lymphocyte Activation Gene-3 (CD223), The Journal of Immunology, vol.168, issue.8, p.387480, 2002. ,
, LAG3 (CD223) as a Cancer Immunotherapy Target, vol.276, pp.80-96, 2017.
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« LBA18Efficacy of BMS-986016, a Monoclonal Antibody That Targets Lymphocyte Activation Gene-3 (LAG-3), in Combination with Nivolumab in Pts with Melanoma Who Progressed during Prior Anti-PD-1/PD-L1 Therapy, All-Comer and Biomarker-Enriched Populations, vol.28, 2017. ,
,
, « High-Dose Recombinant Interleukin 2 Therapy for Patients with Metastatic Melanoma: Analysis of 270 Patients Treated between 1985 and, vol.17, p.210516, 1993.
, « IMMUNOTHERAPY AND EXPERIMENTAL APPROACHES FOR METASTATIC MELANOMA ». Hematology/Oncology Clinics of North America, vol.12, issue.4, p.902, 1998.
« Tumor-Infiltrating Immune Cells as Potential Biomarkers Predicting Response to Treatment and Survival in Patients with Metastatic Melanoma Receiving Ipilimumab Therapy, Cancer Immunology, Immunotherapy, vol.67, issue.1, p.14151, 2018. ,
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« A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells, Cancer Research, vol.74, issue.3, p.66574, 2014. ,
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, Blockade of A 2A Receptors Potently Suppresses the Metastasis of CD73 + Tumors, vol.110, p.1471116, 2013.
, IPH2101, a Novel Anti-Inhibitory KIR Antibody, and Lenalidomide Combine to Enhance the Natural Killer Cell versus Multiple Myeloma Effect, vol.118, p.638791, 2011.
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, « Rationnel biologique de l'immunothérapie des cancers, vol.35, p.20622
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« Blocking Tumor Necrosis Factor ? Enhances CD8 T-Cell-Dependent Immunity in Experimental Melanoma, 2015. ,
« Re: Bacillus Calmette-Guérin Strain Differences Have an Impact on Clinical Outcome in Bladder Cancer Immunotherapy, European Urology, vol.67, issue.2, p.351, 2015. ,
« Verminderung der experimentellen Hepatitis durch den GProtein-gekoppelten Adenosin-A2-Rezeptor, Zeitschrift für Gastroenterologie, vol.40, issue.07, p.543, 2002. ,
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« LBA49Updated Results from KEYNOTE-021 Cohort G: A Randomized, Phase 2 Study of Pemetrexed and Carboplatin (PC) with or without Pembrolizumab (Pembro) as First-Line Therapy for Advanced Nonsquamous NSCLC, Annals of Oncology, vol.28, 2017. ,
, T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway, vol.6, pp.235-60, 2014.
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, Gene Codes for an Antigen Recognized by Autologous Cytolytic T Lymphocytes on HLA-A2 Melanomas, vol.178, p.489
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Pharmacokinetic and Biological Correlative Study of IMP321, a Novel MHC Class II Agonist, in Patients with Advanced Renal Cell Carcinoma, Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, vol.15, p.622531 ,
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, Adjuvant interferon alpha 2b in high risk melanoma-the Scottish study, British Journal of Cancer, vol.84, issue.9, p.114649
« Targeting HLA Class I Expression to Increase Tumor Immunogenicity, Tissue Antigens, vol.79, issue.3, p.14754, 2012. ,
« From the Bench to the Bedside: Ways to Improve Rituximab Efficacy, Blood, vol.104, issue.9, p.263542, 2004. ,
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, Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation, vol.364, p.250716, 2011.
, Anti-PD-1/PD-L1 Therapy of Human Cancer: Past, Present, and Future, vol.125, p.338491, 2015.
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, Combining radiotherapy and ipilimumab induces clinically relevant radiation-induced abscopal effects in metastatic melanoma patients: A systematic review, Clinical and Translational Radiation Oncology, vol.9, p.511
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, On the Receiving End-Patient Perception of the Side-Effects of Cancer Chemotherapy, European Journal of Cancer & Clinical Oncology, vol.19, issue.2, p.2038
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« Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect When Combined with AntiCTLA-4 Antibody, Clinical Cancer Research, vol.15, issue.17, p.537988, 2009. ,
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« PD-1/PD-L1 Pathway: An Adaptive Immune Resistance Mechanism to Immunogenic Chemotherapy in Colorectal Cancer, OncoImmunology, vol.7, issue.6, p.1433981, 2018. ,
« Blockade of Tumor-Expressed PD-1 Promotes Lung Cancer Growth, Oncoimmunology, vol.7, issue.4, 2018. ,
« Encorafenib plus Binimetinib versus Vemurafenib or Encorafenib in Patients with BRAF-Mutant Melanoma (COLUMBUS): A Multicentre, OpenLabel, Randomised Phase 3 Trial, The Lancet Oncology, vol.19, issue.5, pp.30142-30148, 2018. ,
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, Purinergic Signaling during Inflammation, vol.367, p.232233, 2012.
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, « Nanosecond Pulsed Electric Fields Modulate the Expression of Fas/CD95 Death Receptor Pathway Regulators in U937 and Jurkat Cells, vol.19, p.175568
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