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Theses

Les parcours de soins des insuffisants cardiaques : de leur mesure à leur utilisation

Abstract : Heart failure is a frequent and serious chronic pathology, whose evolution is peppered with decompensations that usually require hospitalization. Despite clear scientific recommendations (treatment of etiology and co-morbidities, early symptomatic treatment of decompensations, specific treatment for cases with decreased ejection fraction), the organization of the health system does not promote optimal delivery of recommended care. The literature reports that the delivery of care, as well as the content of delivered care, vary widely from one environment to another, with an impact on the risk of rehospitalization. Therefore, improving the quality of care needs to describe the delivery modalities and the content of care, that is to say, the care pathway. The methods of describing these pathways are rare and non-consensual. The aim of this thesis is to propose methods for describing care pathways, with the aim of offering support for clinical and public health decision-making. Two studies are carried out on two very different bases: an ambulatory and hospital medico-administrative database on a regional scale, and a monocentric clinical hospital database. These two studies highlight, using a hierarchical ascending classification on principal components, easily interpretable groups of patients. In particular, they each show two groups whose clinical characteristics are similar, but whose management is very different; a low level of care is associated with an poor prognosis. The methodology used in these studies is discussed in light of the literature, and the opportunities offered by the findings in terms of research, clinical practice, and public health are explored.
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Claire Duflos. Les parcours de soins des insuffisants cardiaques : de leur mesure à leur utilisation. Médecine humaine et pathologie. Université Montpellier, 2018. Français. ⟨NNT : 2018MONTT065⟩. ⟨tel-02010578⟩

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