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D. Le-mécanisme, import mitochondrial de tRK1 semble reposer sur la colaboration entre plusieurs protéines cytosoliques. Tout d'abord tRK1 est amino-acylé par la lysyl-ARNt synthétase cytosolique (KRS) (Tarassov et al, 1995b), puis reconnue spécifiquement par un complexe protéique contenant une des deux isoformes de l

. Eno2p, Eno2p transporte tRK1 vers la surface mitochondriale où il est pris en charge par le précurseur de la lysyl-ARNt synthétase mitochondriale (preMSK1p) (Tarassov et al, 1995b), qui est produite principalement à proximité des mitochondries (Entelis et al, 2006), Il a été suggéré qu'Eno2p discrimine entre les molecules à importer en induisant la formation d'une structure alternative dénommée forme F (Kolesnikova et al, 2006.

, Liste de publications et communications

M. Baleva, A. Gowher, P. Kamenski, I. Tarassov, N. Entelis et al., , 2015.

, Moonlighting Human Protein Is Involved in Mitochondrial Import of tRNA, Int J Mol Sci, vol.16, pp.9354-9367

M. Baleva, M. Meyer, N. Entelis, I. Tarassov, P. Kamenski et al., Factors beyond enolas 2 and mitochondrial lysyl-tRNA synthetase precursor are required fir tRNA import in yeast mitochondria
DOI : 10.1134/s0006297917110104

M. Baleva, M. Meyer, A. Gowher, N. Entelis, and B. Masquida, «A non-canonical tRNA complex involved in tRNA mitochondrial import» 6th world congress on targeting mitochondria, 2015.

M. Baleva, A. Smirnov, N. Entelis, and I. Tarassov, Masquida, B. «Factors beyond enolas and mitochondrial lysyl-tRNA synthetase precursor are required fir tRNA import tRNA in yeast mitochondria, RNA, 2016.