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, BC risk was regressed on methylation levels of all the CpG sites included in the DMRs for model 1 and on PC scores keeping 80% of information for model 2. Adjustment covariates were alcohol intake, BMI and physical activity

, 2 Number of sites located in DMRs significant for palmitoleic acid

, 3 Number of CpG sites significantly associate with BC risk

, Number of principal components (PC) needed to keep 80% of information in PCA

, 5 Principal components significantly associate with BC risk using model 2

P. Pcdhga11, P. , and P. , PCDHGA cluster of genes including : PCDHGA4