. .. Animals,

. Surgery and .. .. Virus-injection,

. .. Behavior, 63 6.4 2-photon laser-scanning microscope (2PLSM)-based calcium imaging

. .. In-vivo-optogenetics,

. , Chronic imaging of FrA pyramidal neurons during auditory cue discrimination

. , 76 7.2.2 Decorrelation of cue-specific activity patterns predicts cue discrimination, FrA computes both fear and safety sensory cues during learning

. , FrA is required during learning for safety detection

. .. , 80 7.3.1 Subthreshold activation of FrA pyramidal neurons, Auditory stimulation generates frequency-specific plateau potentials

. .. , 88 7.4.3 Activation of BLA inputs during auditory stimulation potentiate FrA neurons, Co-activation of convergent inputs reinforces FrA L2/3 pyramidal neurons, p.88

. , 90 7.5.2 Photo-inhibition of BLA-to-FrA neurons decreases cue discrimination, BLA-to_PFC long-range axons are required for discriminative learning

.. .. ,

. .. Conclusions,

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, Spectral properties of auditory stimulation. b, Example raster plots (top) and peristimulus time histograms (bottom, bin size: 1 s) showing the heterogeneity of neuronal activity among successive auditory stimuli. Each square represents a detected calcium transient. Red and blue bars represent CS-and CS+ epochs

, CS-specific (red), and non-specific (grey, responding to both CS+ and CS-)Effect of fear conditioning (FC) on cumulative PSPs change. Same representation as in e (left) and f (right). (CS-naive, Neurons were categorized as non responding (black), CS+ specific (blue)

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