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?. Taxes and C. Frais,

, Le promoteur souscrit un contrat d'assurance garantissant sa responsabilité civile et celle de tout intervenant à l'étude

, XIV-Publication et valorisation

, Les communications et rapports scientifiques correspondant à cette étude seront réalisés sous la responsabilité de l'investigateur principal de l'étude avec l'accord des investigateurs responsables

, Les coauteurs du rapport et des publications seront les investigateurs et les cliniciens impliqués, au prorata de leur contribution à l'étude, ainsi que les chercheurs associés

, Les règles de publications suivront les recommandations internationales, vol.336, pp.309-315, 1997.

, les essais ne peuvent faire l'objet d'aucun commentaire écrit ou oral sans l'accord conjoint de l'investigateur et du promoteur. Toute publication doit mentionner que le CHRU de Lille est promoteur (No d'identification " AA-NN " à demander à la Délégation à la Recherche). En tout état de cause, Conformément à l'article R 5121-13 du Code de la Santé Publique

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, Bibliographie (ci-dessous)

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, Formulaire de recueil de consentement (ci-joint)

, Formulaire d'inclusion (ci-joint)

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F. Protocol,

F. , Advance SL PET/CT device (GE Medical Systems) with a 5 mm full-width at half-maximum and a 30 cm transaxial field of view. Patients were scanned under resting conditions, after fasting. The blood glucose level was checked before intravenous injection of 18 F-FDG

, Thirty minutes later, a low-dose CT scan of the brain was acquired for attenuation correction of the PET data, and 15-minute emission images were subsequently acquired in 3D mode. Images were reconstructed iteratively using an orderedsubset expectation-maximization algorithm

, This included the preprocessing steps of non-uniform signal correction, signal and spatial normalizations, skull stripping, and brain tissue segmentation. Triangulated surface models of the inner and outer cortical surfaces were obtained for each subject and registered to the Freesurfer fsaverage surface using a spherical, Volumetric T1 images were processed using the software package Freesurfer (v5.1