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, Bien sur il fallait déterminer les autres paramètres du laser (irradiance, temps de tir) permettant d'obtenir une élévation de température bien ciblée. L'objectif était d'obtenir une élévation de la température cutanée jusqu'à 53°C. Ainsi, nous avons calculé qu'en théorie, avec une irradiance de 5,1W/cm 2 , un tir de 10 secondes

, Cependant il persistait tout de même des variations inter-individuelles et intra-individuelles probablement liées à l'hydratation cutanée, l'épaisseur du derme

, Peu d'études ont été publiées concernant le laser-diode 1210 nm. Mais, nos résultats sont en accord avec ceux de Wanner (28) qui utilisait des fluences de 70 à 90 J/cm 2 pour obtenir une élévation de

, Plusieurs études ont montré que l'effet thermique des lasers pouvaient modifier la cicatrisation cutanée en induisant une réaction inflammatoire contrôlée (11, 29, 30)

L. Hsp, Elle est présente dans les fibroblastes. La fonction principale des HSP 70 est de prévenir l'agrégation des protéines, qui pourrait nuire à l'activité cellulaire

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, L'observation portant sur le critère de jugement principal, taux de brulure, sera purement descriptif