Skip to Main content Skip to Navigation
Theses

Etude des facteurs de risque cliniques de maladie veineuse thromboembolique chez les femmes : implication sur la réduction des risques liées à la stratégie diagnostique de l'embolie pulmonaire chez les femmes enceintes

Abstract : Introduction : The diagnostic strategy for PE during pregnancy is uncertain due to the lack of high quality studies and the risk of radiation exposure with computed tomography pulmonary angiography (CTPA) and ventilationperfusion (V-Q) lung scan. The challenge is to validate diagnostic strategies, and to identify predictive factors to reduce the number of additional imaging tests with radiation exposure.First, we aim to identify pitfalls during the diagnostic strategy of PE (the D-dimer assay threshold, clinical probability scores, imaging) during pregnancy. Second, our objective was to compare the diagnostic efficiency of CTPA and (V-Q) lung scan during pregnancy.Third, our objective was to validate a diagnostic strategy wich reduces the number of imaging tests (adjustment of the D-dimer level on the clinical probability). Finally, the last objective was to set up a research program focused on the weight of the family history of MVTE, that may also reduce the need of additional tests. Conclusion : We identified an ongoing validation protocol with a new diagnostic algorithm in pregnant patients withPE suspicion ; Furthermore, identifying a D-dimer level adjustement as well as a family history of VTE can lead tomore effective diagnostic stragegies with less radiation exposure for pregnant women with suspected PE.
Document type :
Theses
Complete list of metadatas

Cited literature [24 references]  Display  Hide  Download

https://tel.archives-ouvertes.fr/tel-01880772
Contributor : Abes Star :  Contact
Submitted on : Tuesday, September 25, 2018 - 10:58:07 AM
Last modification on : Tuesday, October 20, 2020 - 10:56:10 AM
Long-term archiving on: : Wednesday, December 26, 2018 - 2:12:49 PM

File

These-2018-BS-Epidemiologie_an...
Version validated by the jury (STAR)

Identifiers

  • HAL Id : tel-01880772, version 1

Collections

Citation

Cécile Tromeur. Etude des facteurs de risque cliniques de maladie veineuse thromboembolique chez les femmes : implication sur la réduction des risques liées à la stratégie diagnostique de l'embolie pulmonaire chez les femmes enceintes. Médecine humaine et pathologie. Université de Bretagne occidentale - Brest, 2018. Français. ⟨NNT : 2018BRES0021⟩. ⟨tel-01880772⟩

Share

Metrics

Record views

730

Files downloads

681