K. Al-gubory and C. Garrel, Antioxidative signalling pathways regulate the level of reactive oxygen species at the endometrial???extraembryonic membranes interface during early pregnancy, The International Journal of Biochemistry & Cell Biology, vol.44, issue.9, pp.1511-1518, 2012.
DOI : 10.1016/j.biocel.2012.06.017
URL : https://hal.archives-ouvertes.fr/hal-01000907

K. Al-gubory, P. Bolifraud, and C. Garrel, Regulation of Key Antioxidant Enzymatic Systems in the Sheep Endometrium by Ovarian Steroids, Endocrinology, vol.149, issue.9, pp.4428-4434, 2008.
DOI : 10.1210/en.2008-0187

K. Al-gubory, P. Fowler, and C. Garrel, The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes, The International Journal of Biochemistry & Cell Biology, vol.42, issue.10, pp.1634-1650, 2010.
DOI : 10.1016/j.biocel.2010.06.001

K. Al-gubory, C. Garrel, N. Sugino, and P. Fowler, The conceptus induces a switch in protein expression and activities of superoxide dismutase 1 and 2 in the sheep endometrium during early pregnancy, Small Ruminant Research, vol.141, pp.77-83, 2016.
DOI : 10.1016/j.smallrumres.2016.07.006

M. Alexeyev, I. Shokolenko, G. Wilson, and S. Ledoux, The Maintenance of Mitochondrial DNA Integrity--Critical Analysis and Update, Cold Spring Harbor Perspectives in Biology, vol.5, issue.5, 2013.
DOI : 10.1101/cshperspect.a012641
URL : http://cshperspectives.cshlp.org/content/5/5/a012641.full.pdf

J. Arosh, J. Parent, P. Chapdelaine, J. Sirois, and M. Fortier, Expression of Cyclooxygenases 1 and 2 and Prostaglandin E Synthase in Bovine Endometrial Tissue During the Estrous Cycle1, Biology of Reproduction, vol.62, issue.(suppl 1), pp.161-169, 2002.
DOI : 10.1172/JCI13271

S. Asdell, . The, . Sex, . Intersexual, . And et al., THE GENETIC SEX OF INTERSEXUAL GOATS AND A PROBABLE LINKAGE WITH THE GENE FOR HORNLESSNESS, Science, vol.99, issue.2563, p.124, 1944.
DOI : 10.1126/science.99.2563.124

F. Bartol, A. Wiley, D. Coleman, D. Wolfe, and M. Riddell, Ovine Uterine Morphogenesis: Effects of Age and Progestin Administration and Withdrawal on Neonatal Endometrial Development and DNA Synthesis, Journal of Animal Science, vol.66, issue.11, pp.3000-3009, 1988.
DOI : 10.2527/jas1988.66113000x

F. Batista, D. Vaiman, J. Dausset, M. Fellous, and R. Veitia, Potential targets of FOXL2, a transcription factor involved in craniofacial and follicular development, identified by transcriptomics, Proceedings of the National Academy of Sciences of the United States of America, pp.3330-3335, 2007.
DOI : 10.1038/nature01036

S. Bauersachs and E. Wolf, Transcriptome analyses of bovine, porcine and equine endometrium during the pre-implantation phase, Animal Reproduction Science, vol.134, issue.1-2, pp.84-94, 2012.
DOI : 10.1016/j.anireprosci.2012.08.015

S. Bauersachs and E. Wolf, Immune aspects of embryo-maternal cross-talk in the bovine uterus, Journal of Reproductive Immunology, vol.97, issue.1, pp.20-26, 2013.
DOI : 10.1016/j.jri.2012.11.002

S. Bauersachs, S. Ulbrich, K. Gross, S. Schmidt, H. Meyer et al., Gene expression profiling of bovine endometrium during the oestrous cycle: detection of molecular pathways involved in functional changes, Journal of Molecular Endocrinology, vol.34, issue.3, pp.889-908, 2005.
DOI : 10.1677/jme.1.01799

S. Bauersachs, S. Ulbirch, K. Gross, S. Schmidt, H. Meyer et al., Embryo-induced transcriptome changes in bovine endometrium reveal species-specific and common molecular markers of uterine receptivity, Reproduction, vol.5, issue.2, pp.319-331, 2006.
DOI : 10.1186/1471-2105-5-16

S. Bauersachs, C. Simintiras, R. Sturmey, S. Krebs, J. Bick et al., Effect of metabolic status on conceptus???maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome???, Biology of Reproduction, vol.92, issue.Suppl 1, 2017.
DOI : 10.1530/REP-13-0010

F. Bazer, G. Wu, T. Spencer, G. Johnson, R. Burghardt et al., Novel pathways for implantation and establishment and maintenance of pregnancy in mammals, Molecular Human Reproduction, vol.287, issue.1-2, pp.135-152, 2009.
DOI : 10.1016/j.mce.2008.02.012

F. Bazer, G. Wu, T. Spencer, G. Johnson, R. Burghardt et al., Novel pathways for implantation and establishment and maintenance of pregnancy in mammals, Molecular Human Reproduction, vol.287, issue.1-2, pp.135-152, 2010.
DOI : 10.1016/j.mce.2008.02.012

F. Bazer, G. Wu, G. Johnson, J. Kim, and G. Song, Uterine Histotroph and Conceptus Development: Select Nutrients and Secreted Phosphoprotein 1 Affect Mechanistic Target of Rapamycin Cell Signaling in Ewes1, Biology of Reproduction, vol.59, issue.(suppl A), pp.1094-1107, 2011.
DOI : 10.1095/biolreprod59.4.784

F. Bazer, J. Kim, H. Ka, G. Johnson, G. Wu et al., Select Nutrients in the Uterine Lumen of Sheep and Pigs Affect Conceptus Development, Journal of Reproduction and Development, vol.58, issue.2, pp.180-188, 2012.
DOI : 10.1262/jrd.2011-019

B. Bellessort, A. Bachelot, É. Heude, G. Alfama, A. Fontaine et al., Role of Foxl2 in uterine maturation and function, Human Molecular Genetics, vol.20, issue.(Suppl A), pp.24-178, 2014.
DOI : 10.1093/hmg/ddr166
URL : https://hal.archives-ouvertes.fr/hal-02135831

B. Bellessort, L. Cardinal, M. Bachelot, A. Narboux-nême, N. Garagnani et al., control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis, Human Molecular Genetics, vol.25, issue.1, pp.97-108, 2016.
DOI : 10.1093/database/bau012
URL : https://hal.archives-ouvertes.fr/hal-02135783

B. Benayoun, S. Caburet, A. Dipietromaria, M. Bailly-bechet, F. Batista et al., The identification and characterization of a FOXL2 response element provides insights into the pathogenesis of mutant alleles, Human Molecular Genetics, vol.18, issue.20, pp.3118-3127, 2008.
DOI : 10.1093/nar/18.21.6197
URL : https://hal.archives-ouvertes.fr/hal-00428218

B. Benayoun, F. Batista, J. Auer, A. Dipietromaria, L. Hôte et al., Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations, Human Molecular Genetics, vol.26, issue.4, pp.632-644, 2009.
DOI : 10.1128/MCB.00289-06

B. Benayoun, A. Georges, L. Hôtel, D. Andersson, N. Dipietromaria et al., Transcription factor FOXL2 protects granulosa cells from stress and delays cell cycle: role of its regulation by the SIRT1 deacetylase, Human Molecular Genetics, vol.94, issue.9, pp.1673-1686, 2011.
DOI : 10.1016/j.fertnstert.2009.09.050
URL : https://hal.archives-ouvertes.fr/hal-00566930

G. Bernardo and R. Keri, FOXA1: a transcription factor with parallel functions in development and cancer, Bioscience Reports, vol.12, issue.2, pp.113-130, 2012.
DOI : 10.1186/gb-2009-10-11-r129
URL : http://www.bioscirep.org/content/ppbioscirep/32/2/113.full.pdf

D. Beysen, J. Raes, B. Leroy, A. Lucassen, J. Yates et al., Deletions Involving Long-Range Conserved Nongenic Sequences Upstream and Downstream of FOXL2 as a Novel Disease-Causing Mechanism in Blepharophimosis Syndrome, The American Journal of Human Genetics, vol.77, issue.2, pp.205-218, 2005.
DOI : 10.1086/432083

D. Beysen, D. Paepe, A. , D. Baere, and E. , mutations and genomic rearrangements in BPES, Human Mutation, vol.35, issue.Spec No 2, pp.158-169, 2009.
DOI : 10.1016/j.mrfmmm.2004.02.014
URL : http://onlinelibrary.wiley.com/doi/10.1002/humu.20807/pdf

A. Blount, K. Schmidt, N. Justice, W. Vale, W. Fischer et al., FoxL2 and Smad3 Coordinately Regulate Follistatin Gene Transcription, Journal of Biological Chemistry, vol.11, issue.12, pp.7631-7645, 2009.
DOI : 10.1002/humu.20819
URL : http://www.jbc.org/content/284/12/7631.full.pdf

D. Boichard, Impact économique d'une mauvaise fertilité chez la vache laitière, INRA Productions Animales, vol.1, pp.245-252, 1988.

B. Borghese, F. Mondon, J. Noël, I. Fayt, T. Mignot et al., Eutopic Endometrium Provides New Insights into Endometriosis Oncogenic Potential, Molecular Endocrinology, vol.22, issue.11, pp.2557-2562, 2008.
DOI : 10.1210/me.2008-0322
URL : https://academic.oup.com/mend/article-pdf/22/11/2557/8938069/mend2557.pdf

K. Bouhali, A. Dipietromaria, A. Fontaine, S. Caburet, O. Barbieri et al., Allelic reduction of Dlx5 and Dlx6 results in early follicular depletion: a new mouse model of primary ovarian insufficiency, Human Molecular Genetics, vol.6, issue.2, pp.2642-2650, 2011.
DOI : 10.1093/molehr/6.2.146
URL : https://hal.archives-ouvertes.fr/hal-00627689

J. Bouilly, R. Veitia, and N. Binart, NOBOX is a key FOXL2 partner involved in ovarian folliculogenesis, Journal of Molecular Cell Biology, vol.13, issue.2, pp.175-177, 2014.
DOI : 10.1093/hmg/ddh124
URL : https://hal.archives-ouvertes.fr/hal-01132566

L. Boulanger, M. Pannetier, L. Gall, A. Allais-bonnet, M. Elzaiat et al., FOXL2 Is a Female Sex-Determining Gene in the Goat, Current Biology, vol.24, issue.4, pp.404-408, 2014.
DOI : 10.1016/j.cub.2013.12.039
URL : https://doi.org/10.1016/j.cub.2013.12.039

M. Brayman, J. Julian, B. Mulac-jericevic, O. Conneely, D. Edwards et al., Progesterone Receptor Isoforms A and B Differentially Regulate MUC1 Expression in Uterine Epithelial Cells, Molecular Endocrinology, vol.20, issue.10, pp.2278-2291, 2006.
DOI : 10.1210/me.2005-0343
URL : https://academic.oup.com/mend/article-pdf/20/10/2278/10718533/mend2278.pdf

, Cycle oestral et détéction des chaleurs, Bruyas Dépêche Vétérinaire sup, vol.19, pp.9-14, 1991.

W. Butler, Review: Effect of Protein Nutrition on Ovarian and Uterine Physiology in Dairy Cattle, Journal of Dairy Science, vol.81, issue.9, pp.2533-2539, 1998.
DOI : 10.3168/jds.S0022-0302(98)70146-8

W. Butler, Energy balance relationships with follicular development, ovulation and fertility in postpartum dairy cows, Livestock Production Science, vol.83, issue.2-3, pp.211-218, 2003.
DOI : 10.1016/S0301-6226(03)00112-X

W. Butler, Energy balance relationships with follicular development, ovulation and fertility in postpartum dairy cows, Livestock Production Science, vol.83, issue.2-3, pp.211-218, 2003.
DOI : 10.1016/S0301-6226(03)00112-X

O. Buzzio, Z. Lu, C. Miller, T. Unterman, and J. Kim, FOXO1A Differentially Regulates Genes of Decidualization, Endocrinology, vol.147, issue.8, pp.3870-3876, 2006.
DOI : 10.1210/en.2006-0167

A. Carter, Evolution of Placental Function in Mammals: The Molecular Basis of Gas and Nutrient Transfer, Hormone Secretion, and Immune Responses, Physiological Reviews, vol.83, issue.4, pp.1543-1576, 2012.
DOI : 10.1016/j.cellbi.2005.10.015

A. Carvalho, P. Reinaud, N. Forde, G. Healey, C. Eozenou et al., Free French abstract, REPRODUCTION, vol.7, issue.6, pp.545-557, 2014.
DOI : 10.1038/nri2093

, Suppression of Ovarian Follicle Activation in Mice by the Transcription Factor Foxo3a, Castrillon DH Science, vol.301, pp.215-218, 2003.

R. Cerri, H. Rutigliano, R. Chebel, and J. Santos, Period of dominance of the ovulatory follicle influences embryo quality in lactating dairy cows, REPRODUCTION, vol.65, issue.4, pp.813-823, 2009.
DOI : 10.2527/2002.8041053x

R. Cerri, I. Thompson, I. Kim, A. Ealy, P. Hansen et al., Effects of lactation and pregnancy on gene expression of endometrium of Holstein cows at day 17 of the estrous cycle or pregnancy, Journal of Dairy Science, vol.95, issue.10, pp.5657-5675, 2012.
DOI : 10.3168/jds.2011-5114

B. Chance and H. Sies, Hydroperoxide metabolism in mammalian organs., Physiological Reviews, vol.59, issue.3, pp.527-605, 1979.
DOI : 10.1152/physrev.1979.59.3.527

S. Chanock, J. Benna, R. Smith, and B. Babior, The respiratory burst oxidase, The Journal of Biological Chemistry, vol.269, pp.24519-24522, 1994.

G. Charpigny, P. Reinaud, J. Tamby, C. Creminon, J. Martal et al., Endocrinology, vol.138, issue.5, pp.2163-2171, 1997.
DOI : 10.1210/endo.138.5.5148

G. Charpigny, P. Reinaud, C. Créminon, and J. Tamby, Correlation of increased concentration of ovine endometrial cyclooxygenase 2 with the increase in PGE2 and PGD2 in the late luteal phase, Reproduction, vol.117, issue.2, pp.315-324, 1999.
DOI : 10.1530/jrf.0.1170315

J. Cocquet, E. Pailhoux, and F. Jaubert, Evolution and expression of FOXL2, Journal of Medical Genetics, vol.39, issue.12, pp.916-921, 2002.
DOI : 10.1136/jmg.39.12.916

J. Cocquet, D. Baere, E. Gareil, M. Pannetier, M. Xia et al., Structure, evolution and expression of the FOXL2 transcription unit, Cytogenetic and Genome Research, vol.101, issue.3-4, pp.206-211, 2003.
DOI : 10.1159/000074338

Y. Cozler, . Le, V. Lollivier, P. Lacasse, C. Disenhaus et al., Rearing strategy and optimizing first-calving targets in dairy heifers: a review, animal, vol.83, issue.09, pp.1393-1404, 2008.
DOI : 10.1079/PNS19940013
URL : https://hal.archives-ouvertes.fr/hal-00729819

L. Cozler and Y. , Reproduction chez la génisse laitière, 2013.

L. Crisponi, M. Deiana, A. Loi, F. Chiappe, M. Uda et al., The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome, Nature Genetics, vol.22, issue.2, pp.159-166, 2001.
DOI : 10.1093/nar/22.22.4673

A. Darwash, G. Lamming, and J. Woolliams, Abstract, Animal Science, vol.72, issue.02, pp.333-347, 1999.
DOI : 10.1017/S1357729800016234

D. Demetrio, R. Santos, C. Demetrio, and J. Vasconcelos, Factors Affecting Conception Rates Following Artificial Insemination or Embryo Transfer in Lactating Holstein Cows, Journal of Dairy Science, vol.90, issue.11, pp.5073-5082, 2007.
DOI : 10.3168/jds.2007-0223

K. Demmers, K. Derecka, and A. Flint, Trophoblast interferon and pregnancy, Reproduction, vol.121, issue.1, pp.41-49, 2001.
DOI : 10.1530/rep.0.1210041

M. Diskin and D. Morris, Embryonic and Early Foetal Losses in Cattle and Other Ruminants, Reproduction in Domestic Animals, vol.84, issue.Suppl., pp.260-267, 2008.
DOI : 10.1007/978-94-009-5038-2

M. Diskin and J. Sreenan, Expression and detection of oestrus in cattle, Reproduction Nutrition Development, vol.40, issue.5, pp.481-491, 2000.
DOI : 10.1051/rnd:2000112
URL : https://hal.archives-ouvertes.fr/hal-00900404

B. Downey, Regulation of the estrous cycle in domestic animals--a review, Canadian Veterinary Journal, vol.21, pp.301-306, 1980.

P. V. Drion, F. Ectors, C. Hanzen, P. Lonergan, and J. Beckers, , 1996.

. Et-lutéale, Ovulation, corps jaune et lutéolyse, Le Point Vétérinaire, vol.28, issue.2, pp.893-900

A. Ealy and Q. Yang, REVIEW ARTICLE: Control of Interferon-Tau Expression During Early Pregnancy in Ruminants, American Journal of Reproductive Immunology, vol.67, issue.Suppl. 2, pp.95-106, 2009.
DOI : 10.1136/ard.61.suppl_2.ii40

B. Ellsworth, A. Burns, K. Escudero, D. Duval, S. Nelson et al., The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein, Molecular and Cellular Endocrinology, vol.206, issue.1-2, pp.93-111, 2003.
DOI : 10.1016/S0303-7207(03)00235-1

B. Ellsworth, N. Egashira, J. Haller, D. Butts, J. Cocquet et al., FOXL2 in the Pituitary: Molecular, Genetic, and Developmental Analysis, Molecular Endocrinology, vol.20, issue.11, pp.2796-2805, 2006.
DOI : 10.1210/me.2005-0303

M. Elzaiat, L. Jouneau, D. Thépot, C. Klopp, A. Allais-bonnet et al., High-Throughput Sequencing Analyses of XX Genital Ridges Lacking FOXL2 Reveal DMRT1 Up-Regulation Before SOX9 Expression During the Sex-Reversal Process in Goats1, Biology of Reproduction, vol.284, issue.6, pp.1-14, 2014.
DOI : 10.1074/jbc.M109.032086

C. Eozenou, A. V. Carvalho, N. Forde, C. Giraud-delville, L. Gall et al., FOXL2 Is Regulated During the Bovine Estrous Cycle and Its Expression in the Endometrium Is Independent of Conceptus-Derived Interferon Tau1, Biology of Reproduction, vol.42, issue.(2), pp.32-32, 2012.
DOI : 10.1152/physiolgenomics.00107.2010

A. Evans and S. Walsh, The physiology of multifactorial problems limiting the establishment of pregnancy in dairy cattle, Reproduction, Fertility and Development, vol.24, issue.1, pp.233-237, 2012.
DOI : 10.1071/RD11912

C. Farin, K. Imakawa, R. Hansen-1, J. Mcdonnell, C. Murphy et al., Expression of Trophoblastic Interferon Genes in Sheep and Cattle1, Biology of Reproduction, vol.43, issue.2, pp.210-218, 1990.
DOI : 10.1095/biolreprod43.2.210

J. Filant, H. Zhou, and T. Spencer, Progesterone Inhibits Uterine Gland Development in the Neonatal Mouse Uterus1, Biology of Reproduction, vol.20, issue.(Pt 1), pp.1-9, 2012.
DOI : 10.1016/j.gde.2010.06.005

J. Flechon, M. Guillomot, M. Charlier, B. Flechon, and J. Martal, Experimental studies on the elongation of the ewe blastocyst, Reproduction Nutrition D??veloppement, vol.26, issue.4, pp.1017-1024, 1986.
DOI : 10.1051/rnd:19860609
URL : https://hal.archives-ouvertes.fr/hal-00898508

N. Forde, F. Carter, T. Fair, M. Crowe, A. Evans et al., Progesterone-Regulated Changes in Endometrial Gene Expression Contribute to Advanced Conceptus Development in Cattle1, Biology of Reproduction, vol.116, issue.(pt 1), pp.784-794, 2009.
DOI : 10.1055/s-2008-1076714

N. Forde, F. Carter, T. Spencer, F. Bazer, O. Sandra et al., Conceptus-Induced Changes in the Endometrial Transcriptome: How Soon Does the Cow Know She Is Pregnant?1, Biology of Reproduction, vol.84, issue.(suppl 2), pp.144-156, 2011.
DOI : 10.1095/biolreprod.110.085910

N. Forde, O. Gorman, A. Whelan, H. Duffy, P. et al., Lactation-induced changes in metabolic status and follicular-fluid metabolomic profile in postpartum dairy cows, Reproduction, Fertility and Development, vol.28, issue.12, pp.1882-1892, 2015.
DOI : 10.1071/RD14348

J. Friedman and K. Kaestner, The Foxa family of transcription factors in development and metabolism, Cellular and Molecular Life Sciences, vol.63, issue.19-20, pp.2317-2328, 2006.
DOI : 10.1007/s00018-006-6095-6

J. Fujii, Y. Iuchi, and F. Okada, Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system, Reproductive Biology and Endocrinology, vol.3, issue.1, p.43, 2005.
DOI : 10.1186/1477-7827-3-43

E. Gailly-fabre, V. Kerlan, C. , and S. , Pregnancy-associated hormones and fetal-maternal relations]. Annales D'endocrinologie 76, pp.39-50, 2015.

P. Garnsworthy, A. Lock, G. Mann, K. Sinclair, and R. Webb, Nutrition, Metabolism, and Fertility in Dairy Cows: 2. Dietary Fatty Acids and Ovarian Function, Journal of Dairy Science, vol.91, issue.10, pp.3824-3833, 2008.
DOI : 10.3168/jds.2008-1032

A. Georges, B. Benayoun, M. Marongiu, A. Dipietromaria, L. Hôte et al., SUMOylation of the Forkhead Transcription Factor FOXL2 Promotes Its Stabilization/Activation through Transient Recruitment to PML Bodies, PLoS ONE, vol.174, issue.9, 2011.
DOI : 10.1371/journal.pone.0025463.s011
URL : https://hal.archives-ouvertes.fr/hal-00639470

A. Georges, A. Auguste, L. Bessière, A. Vanet, A. Todeschini et al., FOXL2: a central transcription factor of the ovary, Journal of Molecular Endocrinology, vol.25, issue.21, 2013.
DOI : 10.1101/gad.176826.111
URL : https://hal.archives-ouvertes.fr/hal-00880196

A. Georges, A. Auguste, L. Bessière, A. Vanet, A. Todeschini et al., FOXL2: a central transcription factor of the ovary, Journal of Molecular Endocrinology, vol.25, issue.21, pp.1-37, 2013.
DOI : 10.1101/gad.176826.111
URL : https://hal.archives-ouvertes.fr/hal-00880196

M. Geraldo, G. Valente, A. Braz, and C. Martins, The discovery of Foxl2 paralogs in chondrichthyan, coelacanth and tetrapod genomes reveals an ancient duplication in vertebrates, Heredity, vol.35, issue.1, pp.57-65, 2013.
DOI : 10.1016/0092-8674(89)90133-5

Y. Ghochani, J. Saini, P. Mellon, and V. Thackray, FOXL2 Is Involved in the Synergy between Activin and Progestins on the Follicle-Stimulating Hormone ??-Subunit Promoter, Endocrinology, vol.153, issue.4, pp.2023-2033, 2012.
DOI : 10.1210/en.2011-1763
URL : https://academic.oup.com/endo/article-pdf/153/4/2023/8982623/endo2023.pdf

C. Gilbert, K. Jenkins, and D. Wathes, Pulsatile release of oxytocin into the circulation of the ewe during oestrus, mating and the early luteal phase, Reproduction, vol.91, issue.1, pp.337-346, 1991.
DOI : 10.1530/jrf.0.0910337

P. Goddard, W. Allen, and E. Gerring, Genital tract pressures in mares. I. Normal pressures and the effect of physiological events, Theriogenology, vol.23, issue.5, pp.815-827, 1985.
DOI : 10.1016/0093-691X(85)90157-8

O. Gonzalez-recio, E. Ugarte, and A. Bach, Trans-Generational Effect of Maternal Lactation during Pregnancy: A Holstein Cow Model, PLoS ONE, vol.7, issue.1, p.51816, 2012.
DOI : 10.1371/journal.pone.0051816.s001

L. Governini, P. Carrarelli, A. Rocha, V. Leo, . De et al., in Human Endometrium, Reproductive Sciences, vol.21, issue.10, pp.1249-1255, 2014.
DOI : 10.1210/en.2007-0665

C. Gray, R. Burghardt, G. Johnson, F. Bazer, and T. Spencer, Evidence that absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation, Reproduction, vol.124, issue.2, pp.289-300, 2002.
DOI : 10.1530/rep.0.1240289
URL : http://www.reproduction-online.org/content/124/2/289.full.pdf

C. Gray, C. Abbey, P. Beremand, Y. Choi, J. Farmer et al., Identification of Endometrial Genes Regulated by Early Pregnancy, Progesterone, and Interferon Tau in the Ovine Uterus1, Biology of Reproduction, vol.345, issue.2, pp.383-394, 2006.
DOI : 10.1056/NEJMra000763
URL : https://academic.oup.com/biolreprod/article-pdf/74/2/383/10566027/biolreprod0383.pdf

M. Guillomot, Cellular interactions during implantation in domestic ruminants, Journal of Reproduction and Fertility. Supplement, vol.49, pp.39-51, 1995.

, L'implantation Du Blastocyste -La Reproduction Chez Les Mammifères et L'homme, Guillomot M, 2001.

M. Guillomot, J. Fléchon, and S. Wintenberger-torres, Conceptus attachment in the Ewe: an ultrastructural study, Placenta, vol.2, issue.2, pp.169-181, 1981.
DOI : 10.1016/S0143-4004(81)80021-5

S. Gupta, A. Agarwal, J. Banerjee, and J. Alvarez, The Role of Oxidative Stress in Spontaneous Abortion and Recurrent Pregnancy Loss: A Systematic Review, Obstetrical & Gynecological Survey, vol.62, issue.5, pp.335-347, 2007.
DOI : 10.1097/01.ogx.0000261644.89300.df

S. Gupta, N. Aziz, L. Sekhon, R. Agarwal, G. Mansour et al., Lipid Peroxidation and Antioxidant Status in Preeclampsia, Obstetrical & Gynecological Survey, vol.64, issue.11, pp.750-759, 2009.
DOI : 10.1097/OGX.0b013e3181bea0ac

S. Hannenhalli and K. Kaestner, The evolution of Fox genes and their role in development and disease, Nature Reviews Genetics, vol.18, issue.4, pp.233-240, 2009.
DOI : 10.1016/j.hep.2003.09.034

A. Hertig, J. Rock, and E. Adams, A description of 34 human ova within the first 17 days of development, American Journal of Anatomy, vol.34, issue.3, pp.435-493, 1956.
DOI : 10.1016/0002-9378(48)90152-5

Y. Ho, M. Gargano, J. Cao, R. Bronson, I. Heimler et al., Reduced Fertility in Female Mice Lacking Copper-Zinc Superoxide Dismutase, Journal of Biological Chemistry, vol.256, issue.13, pp.7765-7769, 1998.
DOI : 10.1073/pnas.86.8.2761
URL : http://www.jbc.org/content/273/13/7765.full.pdf

M. Hobé, G. Lemercier, and J. Séité, Impact économique de la reproduction, Journées Nationales GTV pp, pp.97-102, 2008.

J. Horcajadas, A. Pellicer, and C. Simón, Wide genomic analysis of human endometrial receptivity: new times, new opportunities, Human Reproduction Update, vol.13, issue.1, pp.77-86, 2007.
DOI : 10.1097/00001703-200106000-00011

T. Hosaka, W. Biggs, D. Tieu, A. Boyer, N. Varki et al., , p.182, 2004.

, Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification, Proceedings of the National Academy of Sciences of the United States of America, vol.101, pp.2975-2980

I. Hue, S. Degrelle, and N. Turenne, Conceptus elongation in cattle: Genes, models and questions, Animal Reproduction Science, vol.134, issue.1-2, pp.19-28, 2012.
DOI : 10.1016/j.anireprosci.2012.08.007
URL : https://hal.archives-ouvertes.fr/hal-01001311

N. Igosheva, A. Abramov, L. Poston, J. Eckert, T. Fleming et al., Maternal Diet-Induced Obesity Alters Mitochondrial Activity and Redox Status in Mouse Oocytes and Zygotes, PLoS ONE, vol.231, issue.2, p.10074, 2010.
DOI : 10.1371/journal.pone.0010074.t003

Y. Ikeda, W. Shen, H. Ingraham, and K. Parker, Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases, Molecular Endocrinology, vol.8, pp.654-662, 1994.

J. Ireland, M. Mihm, E. Austin, M. Diskin, and J. Roche, Historical Perspective of Turnover of Dominant Follicles During the Bovine Estrous Cycle: Key Concepts, Studies, Advancements, and Terms, Journal of Dairy Science, vol.83, issue.7, pp.1648-1658, 2000.
DOI : 10.3168/jds.S0022-0302(00)75033-8

S. Jamieson and P. Fuller, Molecular Pathogenesis of Granulosa Cell Tumors of the Ovary, Endocrine Reviews, vol.33, issue.1, pp.109-144, 2012.
DOI : 10.1210/er.2011-0014

E. Jarvie, S. Hauguel-de-mouzon, S. Nelson, N. Sattar, P. Catalano et al., Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring: Figure 1, Clinical Science, vol.86, issue.3, pp.123-129, 2010.
DOI : 10.1056/NEJMoa0706786

V. Jegou, B. Lan, M. Guenic, G. Trou, D. Jouanne et al., Evaluation de l ' impact économique de la santé en élevage laitier -Enquêtes dans le réseau breton de fermes de référence ETRE Lait Economic impat of health in dairy cattle - Surveys in dairy herds of Brittany, 2006.

N. Justice, A. Blount, E. Pelosi, D. Schlessinger, W. Vale et al., Mutant Animals, Molecular Endocrinology, vol.25, issue.8, pp.1404-1415, 2011.
DOI : 10.1210/me.2011-0093

K. Kashimada, T. Svingen, C. Feng, E. Pelosi, S. Bagheri-fam et al., by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice, The FASEB Journal, vol.8, issue.10, pp.3561-3569, 2011.
DOI : 10.1016/j.devcel.2010.08.010

M. Katoh, M. Igarashi, H. Fukuda, H. Nakagama, and M. Katoh, Cancer genetics and genomics of human FOX family genes, Cancer Letters, vol.328, issue.2, pp.198-206, 2013.
DOI : 10.1016/j.canlet.2012.09.017

S. Kim, J. Weiss, M. Tong, M. Laronda, E. Lee et al., Foxl2, a Forkhead Transcription Factor, Modulates Nonclassical Activity of the Estrogen Receptor-??, Endocrinology, vol.150, issue.11, pp.5085-5093, 2009.
DOI : 10.1210/en.2009-0313

C. Klein, S. Bauersachs, S. Ulbrich, R. Einspanier, H. Meyer et al., Monozygotic Twin Model Reveals Novel Embryo-Induced Transcriptome Changes of Bovine Endometrium in the Preattachment Period1, Biology of Reproduction, vol.14, issue.2, pp.253-264, 2006.
DOI : 10.1091/mbc.E03-01-0009

K. Kohan, R. Carvajal, F. Gabler, D. Vantman, C. Romero et al., Role of the transcriptional factors FOXO1 and PPARG on gene expression of SLC2A4 in endometrial tissue from women with polycystic ovary syndrome, REPRODUCTION, vol.582, issue.1, pp.123-131, 2010.
DOI : 10.1016/j.febslet.2007.11.081

T. Kotilainen, M. Huhtinen, and T. Katila, Sperm-induced leukocytosis in the equine uterus, Theriogenology, vol.41, issue.3, pp.629-636, 1994.
DOI : 10.1016/0093-691X(94)90173-G

F. Kuo, I. Bentsi-barnes, G. Barlow, J. Bae, and M. Pisarska, Sumoylation of Forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene, Cellular Signalling, vol.21, issue.12, pp.1935-1944, 2009.
DOI : 10.1016/j.cellsig.2009.09.001

, La Détection Des Chaleurs et Le Moment de L'insémination, Lacerte, 2003.

M. Laloraya, G. Kumar, and M. Laloraya, A possible role of superoxide anion radical in the process of blastocyst implantation in Musmusculus, Biochemical and Biophysical Research Communications, vol.161, issue.2, pp.762-770, 1989.
DOI : 10.1016/0006-291X(89)92665-X

P. Langendijk, E. Bouwman, N. Soede, M. Taverne, and B. Kemp, Myometrial activity around estrus in sows: spontaneous activity and effects of estrogens, cloprostenol, seminal plasma and clenbuterol, Theriogenology, vol.57, issue.5, pp.1563-1577, 2002.
DOI : 10.1016/S0093-691X(02)00657-X

P. Le-mezec and A. Launay, Le cheptel laitier français Évolution génétique et phénotypique 1993-2013 -Prévision d 'évolution génétique 2013-2019, Compte Rendu N°, pp.14200017-14200018, 2014.

D. Leung, P. Fuller, and C. S. , Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors, The International Journal of Biochemistry & Cell Biology, vol.72, pp.51-54, 2016.
DOI : 10.1016/j.biocel.2016.01.003

T. Lodé, Oviparity or viviparity? That is the question???, Reproductive Biology, vol.12, issue.3, pp.259-264, 2012.
DOI : 10.1016/j.repbio.2012.09.001

K. Loffler, D. Zarkower, and P. Koopman, Is a Conserved, Early-Acting Gene in Vertebrate Ovarian Development, Endocrinology, vol.144, issue.7, pp.3237-3243, 2003.
DOI : 10.1210/en.2002-0095

J. Lydon, D. Mayo, F. Funk, C. Mani, S. Hughes et al., Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities., Genes & Development, vol.9, issue.18, pp.2266-2278, 1995.
DOI : 10.1101/gad.9.18.2266

Z. Lyimo, M. Nielen, W. Ouweltjes, T. Kruip, and F. Van-eerdenburg, Relationship among estradiol, cortisol and intensity of estrous behavior in dairy cattle, Theriogenology, vol.53, issue.9, pp.1783-1795, 2000.
DOI : 10.1016/S0093-691X(00)00314-9

N. Macklon and J. Brosens, The Human Endometrium as a Sensor of Embryo Quality, Biology of Reproduction, vol.91, pp.1-8, 2014.

G. Mann, J. Payne, and G. Lamming, Hormonal regulation of oxytocin-induced prostaglandin F2?? secretion by the bovine and ovine uterus in vivo, Domestic Animal Endocrinology, vol.21, issue.2, pp.127-141, 2001.
DOI : 10.1016/S0739-7240(01)00105-9

N. Mansouri-attia, O. Sandra, A. J. Degrelle, S. Everts, R. Giraud-delville et al., Endometrium as an early sensor of in vitro embryo manipulation technologies, Proceedings of the National Academy of Sciences of the United States of America, pp.5687-5692, 2009.
DOI : 10.1093/bioinformatics/bti023

N. Mansouri-attia, A. J. Reinaud, P. Giraud-delville, C. Taghouti, G. Galio et al., Gene expression profiles of bovine caruncular and intercaruncular endometrium at implantation, Physiological Genomics, vol.39, issue.1, pp.14-27, 2009.
DOI : 10.1016/j.ygeno.2004.02.006

, La dynamique folliculaire chez les bovins, Mariens, 1993.

J. Martal, N. Chêne, L. Huynh, L. Haridon, R. Reinaud et al., IFN-tau: A novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities, Biochimie, vol.80, issue.8-9, pp.755-777, 1998.
DOI : 10.1016/S0300-9084(99)80029-7

D. Mattiske, T. Kume, and B. Hogan, The mouse forkhead gene Foxc1 is required for primordial germ cell migration and antral follicle development, Developmental Biology, vol.290, issue.2, pp.447-458, 2006.
DOI : 10.1016/j.ydbio.2005.12.007

F. Mesquita, R. Ramos, G. Pugliesi, S. Andrade, V. Van-hoeck et al., The Receptive Endometrial Transcriptomic Signature Indicates an Earlier Shift from Proliferation to Metabolism at Early Diestrus in the Cow, Biology of Reproduction, vol.93, p.52, 2015.

L. Mezec and P. , Fertilité des principales races laitières Bilan 1999-2012, p.42, 2014.

K. Mitko, S. Ulbrich, H. Wenigerkind, F. Sinowatz, H. Blum et al., Dynamic changes in messenger RNA profiles of bovine endometrium during the oestrous cycle, REPRODUCTION, vol.565, issue.1, pp.225-240, 2008.
DOI : 10.1113/jphysiol.2004.082420

G. Morgan, F. Wooding, and J. Godkin, Localization of bovine trophoblast protein-1 in the cow blastocyst during implantation: An immunological cryoultrastructural study, Placenta, vol.14, issue.6, pp.641-649, 1993.
DOI : 10.1016/S0143-4004(05)80381-9

L. Moumné, A. Dipietromaria, F. Batista, A. Kocer, M. Fellous et al., Differential aggregation and functional impairment induced by polyalanine expansions in FOXL2, a transcription factor involved in cranio-facial and ovarian development, Human Molecular Genetics, vol.17, issue.7, pp.1010-1019, 2008.
DOI : 10.1093/hmg/ddm373

L. Moumné, F. Batista, B. Benayoun, J. Nallathambi, M. Fellous et al., The mutations and potential targets of the forkhead transcription factor FOXL2, Molecular and Cellular Endocrinology, vol.282, issue.1-2, pp.2-11, 2008.
DOI : 10.1016/j.mce.2007.11.006

B. Mulac-jericevic, Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform, Science, vol.289, issue.5485, pp.1751-1754, 2000.
DOI : 10.1126/science.289.5485.1751

D. Navot, R. Scott, K. Droesch, L. Veeck, H. Liu et al., The window of embryo transfer and the efficiency of human conception in vitro, Fertility and Sterility, vol.55, issue.1, pp.114-118, 1991.
DOI : 10.1016/S0015-0282(16)54069-2

S. Nef and J. Vassalli, Complementary pathways in mammalian female sex determination, Journal of Biology, vol.8, issue.8, p.74, 2009.
DOI : 10.1186/jbiol173

E. Nikolakopoulos and E. Watson, Does artificial insemination with chilled, extended semen reduce the antigenic challenge to the mare's uterus compared with natural service?, Theriogenology, vol.47, issue.2, pp.583-590, 1997.
DOI : 10.1016/S0093-691X(97)00016-2

H. Norman, J. Wright, S. Hubbard, R. Miller, and J. Hutchison, Reproductive status of Holstein and Jersey cows in the United States, Journal of Dairy Science, vol.92, issue.7, pp.3517-3528, 2009.
DOI : 10.3168/jds.2008-1768

A. Okano and K. Okuda, Oxytocin Receptors in the Porcine Myometrium during the Estrous Cycle and Early Pregnancy, Nihon Chikusan Gakkaiho, vol.67, issue.1, pp.102-103, 1996.
DOI : 10.2508/chikusan.67.102

L. Oliveira, R. Barreto, F. Perecin, N. Mansouri-attia, F. Pereira et al., Modulation of Maternal Immune System During Pregnancy in the Cow, Reproduction in Domestic Animals, vol.89, issue.Suppl 1, pp.384-393, 2012.
DOI : 10.1016/j.fertnstert.2007.03.037

E. Pailhoux, B. Vigier, S. Chaffaux, N. Servel, S. Taourit et al., A 11.7-kb deletion triggers intersexuality and polledness in goats, Nature Genetics, vol.144, issue.4, pp.453-458, 2001.
DOI : 10.1073/pnas.91.8.3368

J. Palacio, A. Iborra, Z. Ulcova-gallova, R. Badia, and P. Martínez, The presence of antibodies to oxidative modified proteins in serum from polycystic ovary syndrome patients, Clinical and Experimental Immunology, vol.44, issue.2, pp.217-222, 2006.
DOI : 10.1016/S1471-7697(03)00061-3

M. Pannetier, S. Fabre, F. Batista, A. Kocer, L. Renault et al., FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development, Journal of Molecular Endocrinology, vol.36, issue.3, pp.399-413, 2006.
DOI : 10.1677/jme.1.01947

M. Park, E. Shin, M. Won, J. Kim, H. Go et al., FOXL2 Interacts with Steroidogenic Factor-1 (SF-1) and Represses SF-1-Induced CYP17 Transcription in Granulosa Cells., Molecular Endocrinology, vol.24, pp.1024-1036, 2010.
DOI : 10.1210/endo-meetings.2010.PART1.P3.P1-106
URL : https://academic.oup.com/mend/article-pdf/24/5/1024/8944062/mend1024.pdf

S. Perreault, R. Wolff, and B. Zirkin, The role of disulfide bond reduction during mammalian sperm nuclear decondensation in vivo, Developmental Biology, vol.101, issue.1, pp.160-167, 1984.
DOI : 10.1016/0012-1606(84)90126-X

G. Petit, Nouvelle observation d'hermaphrodisme complexe des voies génitales chez un bouc, 1894.

M. Pisarska, J. Bae, C. Klein, and A. Hsueh, Forkhead L2 Is Expressed in the Ovary and Represses the Promoter Activity of the Steroidogenic Acute Regulatory Gene, Endocrinology, vol.145, issue.7, pp.3424-3433, 2004.
DOI : 10.1210/en.2003-1141

M. Pisarska, G. Barlow, and F. Kuo, Minireview: Roles of the Forkhead Transcription Factor FOXL2 in Granulosa Cell Biology and Pathology, Endocrinology, vol.152, issue.4, pp.1199-1208, 2011.
DOI : 10.1210/en.2010-1041

S. Ponsuksili, E. Murani, M. Schwerin, K. Schellander, D. Tesfaye et al., Gene Expression and DNA-Methylation of Bovine Pretransfer Endometrium Depending on Its Receptivity after In Vitro-Produced Embryo Transfer, PLoS ONE, vol.7, issue.8, 2012.
DOI : 10.1371/journal.pone.0042402.s008

E. Ribeiro, J. Santos, and W. Thatcher, Role of lipids on elongation of the preimplantation conceptus in ruminants, Reproduction, vol.2008, issue.4, pp.152-115, 2016.
DOI : 10.1530/jrf.0.0490113

J. Robbins and A. Bakardjiev, Pathogens and the placental fortress, Current Opinion in Microbiology, vol.15, issue.1, pp.36-43, 2012.
DOI : 10.1016/j.mib.2011.11.006
URL : http://europepmc.org/articles/pmc3265690?pdf=render

R. Roberts, Interferon-tau, a Type 1 interferon involved in maternal recognition of pregnancy, Cytokine & Growth Factor Reviews, vol.18, issue.5-6, pp.403-408, 2007.
DOI : 10.1016/j.cytogfr.2007.06.010

R. Robledo, L. Rajan, X. Li, and T. Lufkin, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development, Genes & Development, vol.16, issue.9, pp.1089-1101, 2002.
DOI : 10.1101/gad.988402
URL : http://genesdev.cshlp.org/content/16/9/1089.full.pdf

J. Roelofs, F. Lopez-gatius, R. Hunter, F. Van-eerdenburg, and C. Hanzen, When is a cow in estrus? Clinical and practical aspects, Theriogenology, vol.74, issue.3, pp.327-344, 2010.
DOI : 10.1016/j.theriogenology.2010.02.016

L. Rowson and R. Moor, EMBRYO TRANSFER IN THE SHEEP: THE SIGNIFICANCE OF SYNCHRONIZING OESTRUS IN THE DONOR AND RECIPIENT ANIMAL, Reproduction, vol.11, issue.2, pp.207-212, 1966.
DOI : 10.1530/jrf.0.0110207

O. Sandra, N. Mansouri-attia, and R. Lea, Novel aspects of endometrial function: a biological sensor of embryo quality and driver of pregnancy success, Reproduction, Fertility and Development, vol.24, issue.1, pp.68-79, 2011.
DOI : 10.1071/RD11908
URL : https://hal.archives-ouvertes.fr/hal-01000781

O. Sandra, F. Constant, V. Carvalho, A. Eoz, C. Nou et al., Maternal organism and embryo biosensoring: insights from ruminants, Journal of Reproductive Immunology, vol.108, pp.105-113, 2015.
DOI : 10.1016/j.jri.2014.12.005

R. Sartori, R. Sartor-bergfelt, S. Mertens, J. Guenther, J. Parrish et al., Fertilization and Early Embryonic Development in Heifers and Lactating Cows in Summer and Lactating and Dry Cows in Winter, Journal of Dairy Science, vol.85, issue.11, pp.2803-2812, 2002.
DOI : 10.3168/jds.S0022-0302(02)74367-1

. Saumande, No Title, Rec. Med. Vet, pp.205-218, 1991.

D. Schmidt, The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance, Development, vol.131, issue.4, pp.933-942, 2004.
DOI : 10.1242/dev.00969
URL : http://dev.biologists.org/content/develop/131/4/933.full.pdf

R. Schreck and P. Baeuerle, A role for oxygen radicals as second messengers, Trends in Cell Biology, vol.1, issue.2-3, pp.39-42, 1991.
DOI : 10.1016/0962-8924(91)90072-H

H. Seegers, X. Malher, C. Fourichon, N. Bareille, and F. Beaudeau, Effets économiques associés aux variations de performances de reproduction en troupeau laitier, Méthodologie Des Problèmes D'inffécondité Chez La Vache Laitière pp, pp.49-58, 1999.

S. Shah, M. Köbel, J. Senz, R. Morin, B. Clarke et al., in Granulosa-Cell Tumors of the Ovary, New England Journal of Medicine, vol.360, issue.26, pp.2719-2729, 2009.
DOI : 10.1056/NEJMoa0902542

I. Sheldon, G. Lewis, S. Leblanc, and R. Gilbert, Defining postpartum uterine disease in cattle, Theriogenology, vol.65, issue.8, pp.1516-1530, 2006.
DOI : 10.1016/j.theriogenology.2005.08.021

I. Sheldon, J. Cronin, G. Healey, C. Gabler, W. Heuwieser et al., Innate immunity and inflammation of the bovine female reproductive tract in health and disease, REPRODUCTION, vol.74, issue.1, pp.148-189, 2014.
DOI : 10.1016/j.theriogenology.2010.05.028

T. Shimizu, S. Krebs, S. Bauersachs, H. Blum, E. Wolf et al., Actions and interactions of progesterone and estrogen on transcriptome profiles of the bovine endometrium, Physiological Genomics, vol.13, issue.4, pp.290-300, 2010.
DOI : 10.1073/pnas.040574197

T. Shirozu, K. Sasaki, M. Kawahara, Y. Yanagawa, M. Nagano et al., Expression dynamics of bovine <i>MX</i> genes in the endometrium and placenta during early to mid pregnancy, Journal of Reproduction and Development, vol.62, issue.1, pp.29-35, 2016.
DOI : 10.1262/jrd.2015-086

S. Snijders, P. Dillon, O. Callaghan, D. Boland, and M. , Effect of genetic merit, milk yield, body condition and lactation number on in vitro oocyte development in dairy cows, Theriogenology, vol.53, issue.4, pp.981-989, 2000.
DOI : 10.1016/S0093-691X(00)00244-2

T. Spencer, G. Johnson, F. Bazer, and R. Burghardt, Implantation mechanisms: insights from the sheep, Reproduction, vol.60, issue.2, pp.657-668, 2004.
DOI : 10.1007/s000180300022
URL : http://www.reproduction-online.org/content/128/6/657.full.pdf

T. Spencer, G. Johnson, F. Bazer, R. Burghardt, and M. Palmarini, Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses, Reproduction, Fertility and Development, vol.19, issue.1, pp.65-78, 2007.
DOI : 10.1071/RD06102

T. Spencer, K. Dunlap, and J. Filant, Comparative developmental biology of the uterus: Insights into mechanisms and developmental disruption, Molecular and Cellular Endocrinology, vol.354, issue.1-2, pp.34-53, 2012.
DOI : 10.1016/j.mce.2011.09.035

G. Stark, I. Kerr, B. Williams, R. Silverman, and R. Schreiber, HOW CELLS RESPOND TO INTERFERONS, Annual Review of Biochemistry, vol.67, issue.1, pp.227-264, 1998.
DOI : 10.1146/annurev.biochem.67.1.227

C. A. Stewart, S. Fisher, Y. Wang, M. Stewart, S. Hewitt et al., Uterine Gland Formation in Mice Is a Continuous Process, Requiring the Ovary after Puberty, But Not after Parturition. Biology of Reproduction, vol.85, pp.954-964, 2011.
DOI : 10.1095/biolreprod.111.091470
URL : https://academic.oup.com/biolreprod/article-pdf/85/5/954/10577314/biolreprod0954.pdf

K. Storey, Oxidative stress: Animal adaptations in nature, Brazilian Journal of Medical and Biological Research, vol.29, pp.1715-1733, 1996.

S. Suarez, Gamete and Zygote Transport, 2014.

N. Sugino, K. Shimamura, S. Takiguchi, M. Ono, M. Nakata et al., , p.186

H. Tamura and M. Ono, Changes in activity of superoxide dismutase in the human endometrium throughout the menstrual cycle and in early pregnancy, Hum Reprod, vol.11, pp.1073-1078, 1996.

M. Takano, Z. Lu, T. Goto, L. Fusi, J. Higham et al., Transcriptional Cross Talk between the Forkhead Transcription Factor Forkhead Box O1A and the Progesterone Receptor Coordinates Cell Cycle Regulation and Differentiation in Human Endometrial Stromal Cells, Molecular Endocrinology, vol.21, issue.10, pp.2334-2349, 2007.
DOI : 10.1210/me.2007-0058

K. Takasawa, K. Kashimada, E. Pelosi, M. Takagi, T. Morio et al., expression by antagonizing WT1 during ovarian development in mice, The FASEB Journal, vol.10, issue.5, pp.2020-2028, 2014.
DOI : 10.1016/j.gde.2005.08.004

S. Talbi, A. Hamilton, K. Vo, S. Tulac, M. Overgaard et al., Molecular Phenotyping of Human Endometrium Distinguishes Menstrual Cycle Phases and Underlying Biological Processes in Normo-Ovulatory Women, Endocrinology, vol.147, issue.3, pp.1097-1121, 2006.
DOI : 10.1210/en.2005-1076

Y. Tan, F. Li, Y. Piao, X. Sun, and Y. Wang, Global gene profiling analysis of mouse uterus during the oestrous cycle, Reproduction, vol.126, issue.2, pp.171-182, 2003.
DOI : 10.1530/rep.0.1260171

M. Thomas, S. Jain, G. Kumar, and M. Laloraya, A programmed oxyradical burst causes hatching of mouse blastocysts, Journal of Cell Science, vol.110, issue.1, pp.1597-1602, 1997.

L. Thompson, A. , and Y. , Impact of Oxidative Stress in Fetal Programming, Journal of Pregnancy, vol.151, issue.3, 2012.
DOI : 10.1038/cddis.2010.60

I. Thompson, R. Cerri, I. Kim, A. Ealy, P. Hansen et al., Effects of lactation and pregnancy on metabolic and hormonal responses and expression of selected conceptus and endometrial genes of Holstein dairy cattle, Journal of Dairy Science, vol.95, issue.10, pp.5645-5656, 2012.
DOI : 10.3168/jds.2011-5113

T. Tibbetts, O. Conneely, O. Malley, and B. , Progesterone via Its Receptor Antagonizes the Pro-Inflammatory Activity of Estrogen in the Mouse Uterus1, Biology of Reproduction, vol.236, issue.5, pp.1158-1165, 1999.
DOI : 10.1038/newbio236150a0

S. Tran, X. Zhou, C. Lafleur, M. Calderon, B. Ellsworth et al., Knockout Mice, Molecular Endocrinology, vol.27, issue.3, pp.407-421, 2013.
DOI : 10.1210/me.2012-1286

J. Troccon and M. Petit, Croissance des génisses et performances ultérieures, INRA Productions Animales, pp.55-64, 1989.

Z. Tu, H. Ran, S. Zhang, G. Xia, B. Wang et al., Molecular determinants of uterine receptivity, The International Journal of Developmental Biology, vol.58, issue.2-3-4, pp.147-154, 2014.
DOI : 10.1387/ijdb.130345wh

M. Uda, C. Ottolenghi, L. Crisponi, J. Garcia, M. Deiana et al., Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development, Human Molecular Genetics, vol.13, issue.11, pp.1171-1181, 2004.
DOI : 10.1098/rspb.1963.0055

N. Uhlenhaut and M. Treier, Forkhead transcription factors in ovarian function, REPRODUCTION, vol.57, issue.4, pp.1-23, 2011.
DOI : 10.1016/0092-8674(89)90133-5

N. Uhlenhaut, J. S. Anlag, K. Eisenberger, T. Sekido, R. Kress et al., Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation, Cell, vol.139, issue.6, pp.1130-1142, 2009.
DOI : 10.1016/j.cell.2009.11.021

D. Vaiman, O. Koutita, A. Oustry, J. Elsen, E. Manfredi et al., Genetic mapping of the autosomal region involved in XX sex-reversal and horn development in goats, Mammalian Genome, vol.46, issue.2, pp.133-137, 1996.
DOI : 10.1002/ajmg.1320460527

D. Vaiman, L. Schibler, . Oustry-vaiman-a, E. Pailhoux, T. Goldammer et al., High-Resolution Human/Goat Comparative Map of the Goat Polled/Intersex Syndrome (PIS): The Human Homologue Is Contained in a Human YAC from HSA3q23, Genomics, vol.56, issue.1, pp.31-39, 1999.
DOI : 10.1006/geno.1998.5691

J. Vasconcelos, D. Demétrio, R. Santos, J. Chiari, C. Rodrigues et al., Factors potentially affecting fertility of lactating dairy cow recipients, Theriogenology, vol.65, issue.1, pp.192-200, 2006.
DOI : 10.1016/j.theriogenology.2005.09.030

H. Verdin, D. Baere, and E. , <i>FOXL2 </i>Impairment in Human Disease, Hormone Research in Paediatrics, vol.77, issue.1, pp.2-11, 2012.
DOI : 10.1159/000335236

V. Victor, M. Rocha, C. Bañuls, A. Alvarez, C. De-pablo et al., Induction of Oxidative Stress and Human Leukocyte/Endothelial Cell Interactions in Polycystic Ovary Syndrome Patients with Insulin Resistance, The Journal of Clinical Endocrinology & Metabolism, vol.96, issue.10, pp.3115-3122, 2011.
DOI : 10.1210/jc.2011-0651

C. Walker, S. Meier, M. Littlejohn, K. Lehnert, J. Roche et al., Modulation of the maternal immune system by the pre-implantation embryo, BMC Genomics, vol.11, issue.1, pp.1-13, 2010.
DOI : 10.1186/1471-2164-11-474

Y. Wang, J. Goldberg, R. Sharma, A. Agarwal, and T. Falcone, Importance portance of reactive oxygen species in the peritoneal fluid of women with endometriosis or idiopathic infertility, Fertility and Sterility, vol.68, issue.5, pp.826-830, 1997.
DOI : 10.1016/S0015-0282(97)00343-9

J. Wang, P. Ray, M. Sim, X. Zhou, K. Lu et al., FOXC1 regulates the functions of human basal-like breast cancer cells by activating NF-??B signaling, Oncogene, vol.15, issue.45, pp.4798-4802, 2012.
DOI : 10.1158/1078-0432.CCR-09-0317

D. Wathes, Mechanisms Linking Metabolic Status and Disease with Reproductive Outcome in the Dairy Cow, Reproduction in Domestic Animals, vol.29, issue.13 Suppl, pp.304-312, 2012.
DOI : 10.1016/j.domaniend.2005.02.019

D. Wathes, M. Fenwick, Z. Cheng, N. Bourne, S. Llewellyn et al., Influence of negative energy balance on cyclicity and fertility in the high producing dairy cow, Theriogenology, vol.68, 2007.
DOI : 10.1016/j.theriogenology.2007.04.006

D. Wathes, Z. Cheng, W. Chowdhury, M. Fenwick, R. Fitzpatrick et al., Negative energy balance alters global gene expression and immune responses in the uterus of postpartum dairy cows, Physiological Genomics, vol.39, issue.1, pp.1-13, 2009.
DOI : 10.1016/S0093-691X(00)00389-7

E. Watson, E. Nikolakopoulos, C. Gilbert, and J. Goode, Oxytocin in the semen and gonads of the stallion, Theriogenology, vol.51, issue.4, pp.855-865, 1999.
DOI : 10.1016/S0093-691X(99)00032-1

D. Weigel, G. Jürgens, F. Küttner, E. Seifert, and H. Jäckle, The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo, Cell, vol.57, issue.4, pp.645-658, 1989.
DOI : 10.1016/0092-8674(89)90133-5

F. Wooding, The role of the binucleate cell in ruminant placental structure, Journal of Reproduction and Fertility. Supplement, vol.31, pp.31-39, 1982.

D. Xu, B. Wang, Y. Xu, Z. Chen, Q. Cui et al., Intracellular ROS mediates gas plasma-facilitated cellular transfection in 2D and 3D cultures, Scientific Reports, vol.36, issue.1, p.27872, 2016.
DOI : 10.2131/jts.36.775
URL : http://www.nature.com/articles/srep27872.pdf

A. Yano, R. Guyomard, B. Nicol, E. Jouanno, E. Quillet et al., An Immune-Related Gene Evolved into the Master Sex-Determining Gene in Rainbow Trout, Oncorhynchus??mykiss, Current Biology, vol.22, issue.15, pp.1423-1428, 2012.
DOI : 10.1016/j.cub.2012.05.045
URL : https://hal.archives-ouvertes.fr/hal-01000319

Y. Zeron, A. Ocheretny, O. Kedar, A. Borochov, D. Sklan et al., Seasonal changes in bovine fertility: relation to developmental competence of oocytes, membrane properties and fatty acid composition of follicles, Reproduction, vol.121, issue.3, pp.447-454, 2001.
DOI : 10.1530/rep.0.1210447

J. Zlotogora, M. Sagi, and T. Cohen, The Blepharophimosis, Ptosis, and Epicanthus Inversus Syndrome: Delineation of Two Types, Am J Hum Genet, vol.35, pp.1020-1027, 1983.

, ANNEXES -189

, Annexes a-Gènes cibles putatifs de FOXL2 dans l'endomètre bovin. La liste des gènes a été obtenue par comparaison in silico des profils transcriptomiques de l'endomètre bovin (Mansouri-Attia et al, 2007.

C. Thèse and . Eozenou, , p.190

. Protocole, Rétro transcription (RT) et PCR quantitative (qPCR) Les ARN totaux sont extraits par lyse des

. Mansouri-attia, Les échantillons sont purifés sur colonne Qiagen avec une étape de traitement à la DNAse (RNeasy mini kit; Qiagen) La quantité d'ARN ainsi que leur intégrité et pureté ont été analysés par Bioanalyzer Agilent 2100 (plateforme @BRIDGe-ICE, INRA Jouy-en-Josas) Les ARN totaux sont stockés à -80°C avant l'analyse. 500 ng d'ARN totaux purifiés sont rétrotranscrits en ADNc par l'enzyme Maxima (Thermo Fisher Scientific) dans 20 µl. La réaction de RT-qPCR est réalisée avec le Master mix SYBR Green et le système Step One Plus (Applied Biosystem) Les primers (Eurogentec) ont été dessinés avec Primer express (logiciel version 3.0, Applied Biosystem) afin d'amplifier spécifiquement les gènes de ménage, 2009.

. Eozenou, 01M ; pH 6) 5 min à température ambiante puis 10 min à 80°C. L'activité péroxidase endogène des cellules est inactivée par un traitement d'H2O2 à 0,01% (Sigma-Aldrich) Les cellules sont incubées toute la nuit à 4°C en présence de l'anticorps dirigé contre FOXL2 produit chez le lapin (dilution 1:250 Normal Donkey Serum) Après rinçage en tampon phosphate, Les lamelles sont incubées en tampon citrate 2012) en tampon phosphate Embryonic and early foetal losses incattle and other ruminants, pp.260-267, 2008.

O. González-recio, E. Ugarte, and A. Bach, Trans-Generational Effect of Maternal Lactation during Pregnancy: A Holstein Cow Model, PLoS ONE, vol.7, issue.1, p.51816
DOI : 10.1371/journal.pone.0051816.s001

D. Valour, Dairy cattle reproduction is a tightly regulated genetic process: Highlights on genes, pathways, and biological processes, Animal Frontiers, vol.96, issue.1, pp.32-41
DOI : 10.1186/1471-2164-11-474
URL : https://hal.archives-ouvertes.fr/hal-01130525

, Posters

, GDR Repro, vol.2015, p.198

, Journée de l'école doctorale 2015 (1er prix poster, Section Reproduction, p.199

, ICAR, vol.2016, p.200

, SRF, vol.2016, p.201

, Publications supplémentaires Analysis of STAT1 expression and biological activity reveals interferon-tau-dependent STAT1-regulated SOCS genes in the bovine endometrium A