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Étude des mécanismes de contrôle cognitif sous-tendant les détériorations et fluctuations d'attention soutenue chez les patients souffrant de schizophrénie et les sujets sains

Abstract : The purpose of this project was to gain more knowledge about cognitive control mechanisms underlying deteriorations and fluctuation of sustained attention in schizophrenia and healthy participants. To that end, we combined the use of behavioral, electrophysiological (event-related potentials and functional connectivity) and subjective measures. Our results revealed spared sustained attention in schizophrenia and a distinct patterns of sustained attention changes in schizophrenia. Deteriorations are underlined by a decrease of reactive mode of cognitive control in patients and by a decrease of proactive mode in controls. Our results also highlighted slightly distinct patterns of precursors of lapses in sustained attention in schizophrenia according to the attentional state. Sustained attention changes are associated with resource depletion in patients, whereas in healthy participants, according to attentional state, they could also be caused by disengagement of cognitive control.
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https://tel.archives-ouvertes.fr/tel-01763163
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Submitted on : Tuesday, April 10, 2018 - 6:22:06 PM
Last modification on : Tuesday, October 20, 2020 - 10:23:01 AM

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HOONAKKER_Marc_2017_ED414.pdf
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  • HAL Id : tel-01763163, version 1

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Marc Hoonakker. Étude des mécanismes de contrôle cognitif sous-tendant les détériorations et fluctuations d'attention soutenue chez les patients souffrant de schizophrénie et les sujets sains. Neurosciences [q-bio.NC]. Université de Strasbourg, 2017. Français. ⟨NNT : 2017STRAJ089⟩. ⟨tel-01763163⟩

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