IntelliGO: a new vector-based semantic similarity measure including annotation origin, BMC Bioinformatics, vol.11, issue.1, p.588, 2010. ,
DOI : 10.1186/1471-2105-11-588
URL : https://hal.archives-ouvertes.fr/inria-00543910
Ontology-guided data preparation for discovering genotype-phenotype relationships, BMC Bioinformatics, vol.9, issue.Suppl 4, p.3, 2008. ,
DOI : 10.1186/1471-2105-9-S4-S3
URL : https://hal.archives-ouvertes.fr/inria-00338669
Feature selection for unsupervised learning, J. Mach. Learn. Res, vol.5, pp.845-889, 2004. ,
An introduction to variable and feature selection, J. Mach. Learn. Res, vol.3, pp.1157-1182, 2003. ,
Data Mining, 2001. ,
DOI : 10.1007/978-1-4899-7993-3_104-2
Irrelevant Features and the Subset Selection Problem, International Conference on Machine Learning, pp.121-129, 1994. ,
DOI : 10.1016/B978-1-55860-335-6.50023-4
Two fca-based methods for mining gene expression data, ICFCA, pp.251-266, 2009. ,
An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies, "Protein Engineering, Design and Selection", vol.9, issue.11, pp.91063-1065, 1996. ,
DOI : 10.1093/protein/9.11.1063
Feature selection in unsupervised learning via evolutionary search, Proceedings of the sixth ACM SIGKDD international conference on Knowledge discovery and data mining , KDD '00, pp.365-369, 2000. ,
DOI : 10.1145/347090.347169
Wrappers for feature subset selection, Artificial Intelligence, vol.97, issue.1-2, pp.273-324, 1997. ,
DOI : 10.1016/S0004-3702(97)00043-X
Toward optimal feature selection, Proceedings of the Thirteenth International Conference on Machine Learning (ICML), pp.284-292, 1996. ,
A side effect resource to capture phenotypic effects of drugs, Molecular Systems Biology, vol.6, 2010. ,
DOI : 10.1093/nar/gkm958
Text Classification Aided by Clustering: a Literature Review, Tools in Artificial Intelligence, 2008. ,
DOI : 10.5772/6083
Subgroup discovery with CN2-SD, J. Mach. Learn. Res, vol.5, pp.153-188, 2004. ,
Analysis and prototyping of biological systems: the abstract biological process model, International Journal of Information and Technology, vol.3, issue.4, pp.216-224, 2005. ,
Many-valued concept lattices for conceptual clustering and information retrieval, ECAI, pp.127-131, 2008. ,
URL : https://hal.archives-ouvertes.fr/inria-00338671
Epidemiology of angina pectoris: Role of natural language processing of the medical record, American Heart Journal, vol.153, issue.4, pp.666-673, 2007. ,
DOI : 10.1016/j.ahj.2006.12.022
Document clustering using word clusters via the information bottleneck method, Proceedings of the 23rd annual international ACM SIGIR conference on Research and development in information retrieval , SIGIR '00, pp.208-215, 2000. ,
DOI : 10.1145/345508.345578
Hierarchical Grouping to Optimize an Objective Function, Journal of the American Statistical Association, vol.58, issue.301, pp.236-244, 1963. ,
DOI : 10.1007/BF02289263
Data mining, ACM SIGMOD Record, vol.31, issue.1, p.3, 2011. ,
DOI : 10.1145/507338.507355
Echocardiographic Evidence for Valvular Toxicity of Benfluorex: A Double-Blind Randomised Trial in Patients with Type 2 Diabetes Mellitus, PLoS ONE, vol.113, issue.6, p.38273 ,
DOI : 10.1371/journal.pone.0038273.s002
A side effect resource to capture phenotypic effects of drugs, Molecular Systems Biology, vol.6, 2010. ,
DOI : 10.1093/nar/gkm958
Drug Target Identification Using Side-Effect Similarity, Science, vol.321, issue.5886, pp.263-266, 2008. ,
DOI : 10.1126/science.1158140
Drug target prediction using adverse event report systems: a pharmacogenomic approach, Bioinformatics, vol.28, issue.18, pp.28-611 ,
DOI : 10.1093/bioinformatics/bts413
Systematic Drug Repositioning Based on Clinical Side-Effects, PLoS ONE, vol.295, issue.12, p.28025, 2011. ,
DOI : 10.1371/journal.pone.0028025.s008
Mapping Adverse Drug Reactions in Chemical Space, Journal of Medicinal Chemistry, vol.52, issue.9, pp.523103-3107, 2009. ,
DOI : 10.1021/jm801546k
Building the process-drug???side effect network to discover the relationship between biological Processes and side effects, BMC Bioinformatics, vol.12, issue.Suppl 2, pp.12-14, 2011. ,
DOI : 10.1155/2009/405016
Drug Side-Effect Prediction Based on the Integration of Chemical and Biological Spaces, Journal of Chemical Information and Modeling, vol.52, issue.12, pp.3284-3292 ,
DOI : 10.1021/ci2005548
IntelliGO: a new vector-based semantic similarity measure including annotation origin, BMC Bioinformatics, vol.11, issue.1, p.588, 2010. ,
DOI : 10.1186/1471-2105-11-588
URL : https://hal.archives-ouvertes.fr/inria-00543910
a comprehensive resource for 'omics' research on drugs, Database issue), pp.39-1035, 2011. ,
Open Babel: An open chemical toolbox, Journal of Cheminformatics, vol.3, issue.1, p.33, 2011. ,
DOI : 10.1093/nar/gkp324
Fast computation, rotation, and comparison of low resolution spherical harmonic molecular surfaces, 4<383::AID-JCC1>3.0.CO;2-M], pp.383-3951096, 1999. ,
URL : https://hal.archives-ouvertes.fr/inria-00434275
SHEF: a vHTS geometrical filter using coefficients of spherical harmonic molecular surfaces, Journal of Molecular Modeling, vol.14, issue.2, pp.393-401, 2008. ,
DOI : 10.1007/s00894-008-0286-z
URL : https://hal.archives-ouvertes.fr/inria-00339120
Hierarchical Grouping to Optimize an Objective Function, Journal of the American Statistical Association, vol.58, issue.301, pp.236-244, 1963. ,
DOI : 10.1007/BF02289263
An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies, "Protein Engineering, Design and Selection", vol.9, issue.11, pp.1063-1065, 1996. ,
DOI : 10.1093/protein/9.11.1063
The Protein Data Bank, Nucleic Acids Research, vol.28, issue.1, pp.235-242, 2000. ,
DOI : 10.1093/nar/28.1.235
The IntAct molecular interaction database in 2012, Nucleic Acids Research, vol.40, issue.D1, pp.40-841 ,
DOI : 10.1093/nar/gkr1088
KEGG for integration and interpretation of large-scale molecular data sets, Nucleic Acids Research, vol.40, issue.D1, pp.40-109 ,
DOI : 10.1093/nar/gkr988
PID: the Pathway Interaction Database, Nucleic Acids Research, vol.37, issue.Database, pp.674-679, 2009. ,
DOI : 10.1093/nar/gkn653
QuickGO: a web-based tool for Gene Ontology searching, Bioinformatics, vol.25, issue.22, pp.253045-3046, 2009. ,
DOI : 10.1093/bioinformatics/btp536
InterPro in 2011: new developments in the family and domain prediction database, Nucleic Acids Res, vol.2012, pp.40-306 ,
URL : https://hal.archives-ouvertes.fr/hal-00697960
Use of domain knowledge for dimension reduction -application to mining of drug side effects, Proceedings of the International Conference on Knowledge Discovery and Information Retrieval. SciTePress Digital Library, pp.271-276 ,
URL : https://hal.archives-ouvertes.fr/hal-00642520
Symbolic data mining methods with the Coron platform, 2006. ,
URL : https://hal.archives-ouvertes.fr/tel-00336374
The WEKA data mining software, ACM SIGKDD Explorations Newsletter, vol.11, issue.1, pp.10-18, 2009. ,
DOI : 10.1145/1656274.1656278
Biochemical Knowledge Discovery Using Inductive Logic Programming, Discovey Science, Volume 1532 of Lecture Notes in Computer Science. Edited by Arikawa S, Motoda H, pp.326-341, 1998. ,
DOI : 10.1007/3-540-49292-5_29
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.23.2063
Biological applications of multi-relational data mining, ACM SIGKDD Explorations Newsletter, vol.5, issue.1, pp.69-79, 2003. ,
DOI : 10.1145/959242.959250
Automated identification of protein-ligand interaction features using Inductive Logic Programming: a hexose binding case study, BMC Bioinformatics, vol.13, issue.1, p.162, 2012. ,
DOI : 10.1093/protein/13.2.89
Formal concept analysis for the interpretation of relational learning applied on 3D protein-binding sites SciTePress Digital Library, Proceedings of the International Conference on Knowledge Discovery and Information Retrieval, pp.111-120 ,
A smooth introduction to symbolic methods for knowledge discovery In Handbook of Categorization in Cognitive Science, pp.913-933, 2005. ,
Gene prioritization through genomic data fusion, Nature Biotechnology, vol.352, issue.5, pp.537-544, 2006. ,
DOI : 10.1038/nbt1203
Visualization of protein interaction networks: problems and solutions, BMC Bioinformatics, vol.14, issue.Suppl 1, p.1, 2013. ,
DOI : 10.1093/bioinformatics/bti551
Spasma-in-flexion syndrome, callosal agenesis, chorioretinal abnormalities, Arch. Fr. Pediatr, vol.26, issue.10, pp.1103-1120, 1969. ,
A new syndrome : Spasms in flexion, callosal agenesis, ocular abnormalities, Electroencephalogr. Clin. Neurophysiol, vol.19, pp.609-610, 1965. ,
The Cell as a Collection of Protein Machines: Preparing the Next Generation of Molecular Biologists, Cell, vol.92, issue.3, pp.291-294, 1998. ,
DOI : 10.1016/S0092-8674(00)80922-8
Protein Repeats: Structures, Functions, and Evolution, Journal of Structural Biology, vol.134, issue.2-3, pp.117-131, 2001. ,
DOI : 10.1006/jsbi.2001.4392
Illuminating drug discovery with biological pathways, FEBS Letters, vol.100, issue.8, pp.1872-1877, 2005. ,
DOI : 10.1016/j.febslet.2005.02.023
An Algorithmic Framework for Predicting Side Effects of Drugs, Journal of Computational Biology, vol.18, issue.3, pp.207-218, 2011. ,
DOI : 10.1089/cmb.2010.0255
A New Methodology to Associate SNPs with Human Diseases According to Their Pathway Related Context, PLoS ONE, vol.43, issue.10, p.26277, 2011. ,
DOI : 10.1371/journal.pone.0026277.s004
DISCOVERING REGULATED NETWORKS DURING HIV-1 LATENCY AND REACTIVATION, Biocomputing 2006, pp.354-366, 2006. ,
DOI : 10.1142/9789812701626_0033
Network medicine: a network-based approach to human disease, Nature Reviews Genetics, vol.4, issue.1, pp.56-68, 2011. ,
DOI : 10.1038/nrg2918
Multifunctional proteins revealed by overlapping clustering in protein interaction network, Bioinformatics, vol.28, issue.1, pp.84-90, 2012. ,
DOI : 10.1093/bioinformatics/btr621
URL : https://hal.archives-ouvertes.fr/hal-00877694
Integrated Bio-Entity Network: A System for Biological Knowledge Discovery, PLoS ONE, vol.1, issue.6, p.21474, 2011. ,
DOI : 10.1371/journal.pone.0021474.s001
IntelliGO: a new vector-based semantic similarity measure including annotation origin, BMC Bioinformatics, vol.11, issue.1, p.588, 2010. ,
DOI : 10.1186/1471-2105-11-588
URL : https://hal.archives-ouvertes.fr/inria-00543910
The Protein Data Bank, Nucleic Acids Research, vol.28, issue.1, pp.235-242, 2000. ,
DOI : 10.1093/nar/28.1.235
Substructure-based support vector machine classifiers for prediction of adverse effects in diverse classes of drugs, Journal of Chemical Information and Modeling, issue.6, pp.46-2478, 2006. ,
Linked Data - The Story So Far, International Journal on Semantic Web and Information Systems, vol.5, issue.3, pp.1-22, 2009. ,
DOI : 10.4018/jswis.2009081901
Polypharmacology in a Single Drug: Multitarget Drugs, Current Medicinal Chemistry, vol.20, issue.13, 2013. ,
DOI : 10.2174/0929867311320130004
Graphml progress report, Graph Drawing pp, pp.501-512, 2001. ,
Predicting Adverse Drug Events Using Pharmacological Network Models, Science Translational Medicine, vol.3, issue.114, pp.114-127, 2011. ,
DOI : 10.1126/scitranslmed.3002774
Drug Target Identification Using Side-Effect Similarity, Science, vol.321, issue.5886, pp.321-263, 2008. ,
DOI : 10.1126/science.1158140
AmiGO: online access to ontology and annotation data, Bioinformatics, vol.25, issue.2, pp.288-289, 2009. ,
DOI : 10.1093/bioinformatics/btn615
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to agerelated macular degeneration, Proc. Natl. Acad. Sci. U.S.A, pp.7401-7406, 2010. ,
DOI : 10.1073/pnas.0912702107
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867722
Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference, PLoS Computational Biology, vol.110, issue.5, p.1002503, 2012. ,
DOI : 10.1371/journal.pcbi.1002503.s013
A Validated Regulatory Network for Th17 Cell Specification, Cell, vol.151, issue.2, pp.289-303, 2012. ,
DOI : 10.1016/j.cell.2012.09.016
Protein domain analysis in the era of complete genomes, FEBS Letters, vol.11, issue.1, pp.129-134, 2002. ,
DOI : 10.1016/S0014-5793(01)03289-6
EVA: Exome Variation Analyzer, an efficient and versatile tool for filtering strategies in medical genomics, BMC Bioinformatics, vol.13, issue.Suppl 14, p.9, 2012. ,
DOI : 10.1186/1471-2105-13-S14-S9
URL : https://hal.archives-ouvertes.fr/inserm-00730215
FINDING GENOME-TRANSCRIPTOME-PHENOME ASSOCIATION WITH STRUCTURED ASSOCIATION MAPPING AND VISUALIZATION IN GENAMAP, Biocomputing 2012, pp.327-338, 2012. ,
DOI : 10.1142/9789814366496_0032
The BioPAX community standard for pathway data sharing, Nature Biotechnology, vol.35, issue.9, pp.935-942, 2010. ,
DOI : 10.1038/nbt.1666
Echocardiographic Evidence for Valvular Toxicity of Benfluorex: A Double-Blind Randomised Trial in Patients with Type 2 Diabetes Mellitus, PLoS ONE, vol.113, issue.6, p.38273, 2012. ,
DOI : 10.1371/journal.pone.0038273.s002
Clinical, cytogenetic, and pedigree findings in 18 cases of Aicardi syndrome, American Journal of Medical Genetics, vol.191, issue.4, pp.461-467, 1989. ,
DOI : 10.1002/ajmg.1320320405
A new sequence motif linking lissencephaly, Treacher Collins and oral-facial-digital type 1 syndromes, microtubule dynamics and cell migration, Human Molecular Genetics, vol.10, issue.24, pp.2813-2820, 2001. ,
DOI : 10.1093/hmg/10.24.2813
Systems biology markup language: Level 2 and beyond, Biochemical Society Transactions, vol.31, issue.6, pp.31-1472, 2003. ,
DOI : 10.1042/bst0311472
Benfluorex and Unexplained Valvular Heart Disease: A Case-Control Study, PLoS ONE, vol.5, issue.4, p.10128, 2010. ,
DOI : 10.1371/journal.pone.0010128.t002
URL : https://hal.archives-ouvertes.fr/hal-00678696
A similarity-based method for genome-wide prediction of disease-relevant human genes, Bioinformatics, vol.18, issue.Suppl 2, pp.110-115, 2002. ,
DOI : 10.1093/bioinformatics/18.suppl_2.S110
Exploiting hierarchical domain structure to compute similarity, ACM Transactions on Information Systems, vol.21, issue.1, pp.64-93, 2003. ,
DOI : 10.1145/635484.635487
Exploring the human diseasome: the human disease network, Briefings in Functional Genomics, vol.11, issue.6, pp.533-542, 2012. ,
DOI : 10.1093/bfgp/els032
Mining multi-item drug adverse effect associations in spontaneous reporting systems, BMC Bioinformatics, vol.11, issue.Suppl 9, p.7, 2010. ,
DOI : 10.1186/1471-2105-11-S9-S7
The druggable genome, Nature Reviews Drug Discovery, vol.180, issue.9, pp.727-730, 2002. ,
DOI : 10.1126/science.287.5461.2204
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nature Protocols, vol.99, issue.1, pp.44-57, 2009. ,
DOI : 10.1038/nprot.2008.211
Predicting adverse side effects of drugs, BMC Genomics, vol.12, issue.Suppl 5, p.11, 2011. ,
DOI : 10.1186/1471-2164-12-S5-S11
Discovering regulatory and signalling circuits in molecular interaction networks, Bioinformatics, vol.18, issue.Suppl 1, pp.233-240, 2002. ,
DOI : 10.1093/bioinformatics/18.suppl_1.S233
A comprehensive two-hybrid analysis to explore the yeast protein interactome, Proceedings of the National Academy of Sciences, vol.98, issue.8, pp.98-4569, 2001. ,
DOI : 10.1073/pnas.061034498
Lethality and centrality in protein networks, Nature, issue.6833, pp.411-452, 2001. ,
Modulation of Neuritogenesis by a Protein Implicated in X-Linked Mental Retardation, Journal of Neuroscience, vol.29, issue.40, pp.29-12419, 2009. ,
DOI : 10.1523/JNEUROSCI.5954-08.2009
Reactome: a knowledgebase of biological pathways, Nucleic Acids Research, vol.33, issue.Database issue, pp.33-428, 2005. ,
DOI : 10.1093/nar/gki072
Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci, Science, vol.264, issue.5165, pp.264-1604, 1994. ,
DOI : 10.1126/science.8202715
Benchmarking of HPCC: A novel 3D molecular representation combining shape and pharmacophoric descriptors for efficient molecular similarity assessments, Journal of Molecular Graphics and Modelling, vol.41, pp.20-30, 2013. ,
DOI : 10.1016/j.jmgm.2013.01.003
URL : https://hal.archives-ouvertes.fr/hal-01101863
The IntAct molecular interaction database in 2012, Nucleic Acids Research, vol.40, issue.D1, pp.40-841, 2012. ,
DOI : 10.1093/nar/gkr1088
From local patterns to global models : the lego approach to data mining, 2008. ,
DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs, Nucleic Acids Research, vol.39, issue.Database, pp.39-1035, 2011. ,
DOI : 10.1093/nar/gkq1126
Graph-based analysis and visualization of experimental results with ONDEX, Bioinformatics, vol.22, issue.11, pp.22-1383, 2006. ,
DOI : 10.1093/bioinformatics/btl081
A side effect resource to capture phenotypic effects of drugs, Molecular Systems Biology, vol.6, p.343, 2010. ,
DOI : 10.1093/nar/gkm958
The Human Proteins MBD5 and MBD6 Associate with Heterochromatin but They Do Not Bind Methylated DNA, PLoS ONE, vol.25, issue.8, p.11982, 2010. ,
DOI : 10.1371/journal.pone.0011982.t003
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease, Science, vol.313, issue.5795, pp.313-1929, 2006. ,
DOI : 10.1126/science.1132939
Building the process-drug???side effect network to discover the relationship between biological Processes and side effects, BMC Bioinformatics, vol.12, issue.Suppl 2, p.2, 2011. ,
DOI : 10.1155/2009/405016
BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models, BMC Systems Biology, vol.4, issue.1, p.92, 2010. ,
DOI : 10.1186/1752-0509-4-92
Prediction of potential drug targets based on simple sequence properties, BMC Bioinformatics, vol.8, issue.1, p.353, 2007. ,
DOI : 10.1186/1471-2105-8-353
Data mining methodologies for pharmacovigilance, ACM SIGKDD Explorations Newsletter, vol.14, issue.1, pp.35-42, 2012. ,
DOI : 10.1145/2408736.2408742
Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs, Journal of the American Medical Informatics Association, vol.19, issue.e1, pp.19-28, 2012. ,
DOI : 10.1136/amiajnl-2011-000699
Network analysis of FDA approved drugs and their targets, Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine, vol.313, issue.1, pp.27-32, 2007. ,
DOI : 10.1002/msj.20002
BiNGO: a Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks, Bioinformatics, vol.21, issue.16, pp.3448-3449, 2005. ,
DOI : 10.1093/bioinformatics/bti551
BisoGenet: a new tool for gene network building, visualization and analysis, BMC Bioinformatics, vol.11, issue.1, p.91, 2010. ,
DOI : 10.1186/1471-2105-11-91
Do Structurally Similar Molecules Have Similar Biological Activity?, Journal of Medicinal Chemistry, vol.45, issue.19, pp.45-4350, 2002. ,
DOI : 10.1021/jm020155c
The Dimerization Mechanism of LIS1 and its Implication for Proteins Containing the LisH Motif, Journal of Molecular Biology, vol.357, issue.2, pp.621-631, 2006. ,
DOI : 10.1016/j.jmb.2006.01.002
The MedDRA paradox, AMIA Annu Symp Proc pp, pp.470-474, 2008. ,
Aicardi syndrome in two sisters, The Journal of Pediatrics, vol.115, issue.2, pp.282-283, 1989. ,
DOI : 10.1016/S0022-3476(89)80085-X
Biochemical Knowledge Discovery Using Inductive Logic Programming, Discovery Science pp, pp.326-341, 1998. ,
DOI : 10.1007/3-540-49292-5_29
SCOP: A structural classification of proteins database for the investigation of sequences and structures, Journal of Molecular Biology, vol.247, issue.4, pp.536-540, 1995. ,
DOI : 10.1016/S0022-2836(05)80134-2
Modim : modeldriven data integration for mining, Journées Ouvertes de Biologie, 2011. ,
Genome-wide association study of advanced agerelated macular degeneration identifies a role of the hepatic lipase gene (LIPC), Proc. Natl. Acad. Sci. U.S.A, pp.7395-7400, 2010. ,
Computation with the KEGG pathway database, Biosystems, vol.47, issue.1-2, pp.119-128, 1998. ,
DOI : 10.1016/S0303-2647(98)00017-3
CATH ??? a hierarchic classification of protein domain structures, Structure, vol.5, issue.8, pp.5-1093, 1997. ,
DOI : 10.1016/S0969-2126(97)00260-8
Use of contiguity on the chromosome to predict functional coupling, In Silico Biol. (Gedrukt), vol.1, issue.2, pp.93-108, 1999. ,
Biological applications of multi-relational data mining, SIGKDD Explorations pp, pp.69-79, 2003. ,
DOI : 10.1145/959242.959250
Understanding gene essentiality by finely characterizing hubs in the yeast protein interaction network, Biochemical and Biophysical Research Communications, vol.401, issue.1, pp.112-116, 2010. ,
DOI : 10.1016/j.bbrc.2010.09.021
Predicting drug side-effect profiles: a chemical fragment-based approach, BMC Bioinformatics, vol.12, issue.1, p.169, 2011. ,
DOI : 10.1093/biostatistics/kxp008
URL : https://hal.archives-ouvertes.fr/inserm-00663945
A survey of visualization tools for biological network analysis, BioData Mining, vol.21, issue.24, p.12, 2008. ,
DOI : 10.1093/bioinformatics/bti718
Computational approaches to disease-gene prediction: rationale, classification and successes, FEBS Journal, vol.34, issue.5, pp.678-696, 2012. ,
DOI : 10.1111/j.1742-4658.2012.08471.x
The Tandem Affinity Purification (TAP) Method: A General Procedure of Protein Complex Purification, Methods, vol.24, issue.3, pp.24-218, 2001. ,
DOI : 10.1006/meth.2001.1183
Unveiling the role of network and systems biology in drug discovery, Trends in Pharmacological Sciences, vol.31, issue.3, pp.31-115, 2010. ,
DOI : 10.1016/j.tips.2009.11.006
Inter- ProScan : protein domains identifier, Nucleic Acids Res, pp.33-116, 2005. ,
DOI : 10.1093/nar/gki442
URL : http://doi.org/10.1093/nar/gki442
Matching Star Schemas, pp.428-438, 2011. ,
DOI : 10.1007/s10619-007-7022-z
Correction: Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study, PLoS ONE, vol.8, issue.7, p.66978, 2013. ,
DOI : 10.1371/annotation/d8311dd7-2499-4ef1-b731-b4830b1612df
De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome, Pilz,D.T. et Dobyns,W.B. (2012) De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome, pp.440-444 ,
DOI : 10.1101/gr.6861907
Genetics of Early Onset Cognitive Impairment, Annual Review of Genomics and Human Genetics, vol.11, issue.1, pp.161-187, 2010. ,
DOI : 10.1146/annurev-genom-082509-141640
Towards a proteome-scale map of the human protein???protein interaction network, Nature, vol.23, issue.7062, pp.437-1173, 2005. ,
DOI : 10.1126/science.1090100
Quantitative analysis on the characteristics of targets with FDA approved drugs, International Journal of Biological Sciences, vol.4, issue.1, pp.15-22, 2008. ,
DOI : 10.7150/ijbs.4.15
Automated identification of protein-ligand interaction features using Inductive Logic Programming: a hexose binding case study, BMC Bioinformatics, vol.13, issue.1, p.162, 2012. ,
DOI : 10.1093/protein/13.2.89
PID: the Pathway Interaction Database, Nucleic Acids Research, vol.37, issue.Database, pp.37-674, 2009. ,
DOI : 10.1093/nar/gkn653
Digenic inheritance in medical genetics, Journal of Medical Genetics, vol.132, issue.Suppl 1, 2013. ,
DOI : 10.1136/jmedgenet-2013-101713
Gaining Insight into Off-Target Mediated Effects of Drug Candidates with a Comprehensive Systems Chemical Biology Analysis, Journal of Chemical Information and Modeling, vol.49, issue.2, pp.308-317, 2009. ,
DOI : 10.1021/ci800344p
Mapping Adverse Drug Reactions in Chemical Space, Journal of Medicinal Chemistry, vol.52, issue.9, pp.52-3103, 2009. ,
DOI : 10.1021/jm801546k
Arena3D: visualizing time-driven phenotypic differences in biological systems, BMC Bioinformatics, vol.13, issue.1, p.45, 2012. ,
DOI : 10.1093/nar/gkp972
Cytoscape 2.8: new features for data integration and network visualization, Bioinformatics, vol.27, issue.3, pp.27-431, 2011. ,
DOI : 10.1093/bioinformatics/btq675
A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules, Science, vol.302, issue.5643, pp.302-249, 2003. ,
DOI : 10.1126/science.1087447
Facial and physical features of Aicardi syndrome: Infants to teenagers, American Journal of Medical Genetics Part A, vol.121, issue.3, pp.138-254, 2005. ,
DOI : 10.1002/ajmg.a.30963
Drug target prediction using adverse event report systems: a pharmacogenomic approach, Bioinformatics, vol.28, issue.18, pp.28-611, 2012. ,
DOI : 10.1093/bioinformatics/bts413
Data-Driven Prediction of Drug Effects and Interactions, Science Translational Medicine, vol.4, issue.125, pp.125-156, 2012. ,
DOI : 10.1126/scitranslmed.3003377
The oxl format for the exchange of integrated datasets, J. Integrative Bioinformatics, 2007. ,
Network visualization and analysis of gene expression data using BioLayout Express3D, Nature Protocols, vol.4, issue.10, pp.1535-1550, 2009. ,
DOI : 10.1002/spe.4380211102
ENDEAVOUR update: a web resource for gene prioritization in multiple species, Nucleic Acids Research, vol.36, issue.Web Server, pp.36-377, 2008. ,
DOI : 10.1093/nar/gkn325
Genetic and Epigenetic Networks in Intellectual Disabilities, Annual Review of Genetics, vol.45, issue.1, pp.81-104, 2011. ,
DOI : 10.1146/annurev-genet-110410-132512
An empirical framework for binary interactome mapping, Nature Methods, vol.6, issue.1, pp.83-90, 2009. ,
DOI : 10.1038/nprot.2006.14
A de novo paradigm for mental retardation, Nature Genetics, vol.38, issue.12, pp.42-1109, 2010. ,
DOI : 10.2307/2283970
Drug-Target Networks, Molecular Informatics, vol.76, issue.1-2, pp.10-14, 2010. ,
DOI : 10.1002/minf.200900069
SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations, Nucleic Acids Research, vol.41, issue.D1, pp.41-834, 2013. ,
DOI : 10.1093/nar/gks1040
Prioritization of Retinal Disease Genes: An Integrative Approach, Human Mutation, vol.88, issue.6, 2013. ,
DOI : 10.1002/humu.22317
Protein Interaction Mapping in C. elegans Using Proteins Involved in Vulval Development, Science, vol.287, issue.5450, pp.287-116, 2000. ,
DOI : 10.1126/science.287.5450.116
Regulation of Set9-Mediated H4K20 Methylation by a PWWP Domain Protein, Molecular Cell, vol.33, issue.4, pp.428-437, 2009. ,
DOI : 10.1016/j.molcel.2009.02.002
Network-based drug repositioning, Molecular BioSystems, vol.3, issue.6, 2013. ,
DOI : 10.1136/amiajnl-2012-001168
Drug Side-Effect Prediction Based on the Integration of Chemical and Biological Spaces, Journal of Chemical Information and Modeling, vol.52, issue.12, pp.3284-3292, 2012. ,
DOI : 10.1021/ci2005548
Genes linked by fusion events are generally of the same functional category: A systematic analysis of 30 microbial genomes, Proceedings of the National Academy of Sciences, vol.98, issue.14, pp.98-7940, 2001. ,
DOI : 10.1073/pnas.141236298
Quantitative systems-level determinants of human genes targeted by successful drugs, Genome Research, vol.18, issue.2, pp.206-213, 2008. ,
DOI : 10.1101/gr.6888208
Drug-target network, Nat. Biotechnol, issue.10, pp.25-1119, 2007. ,
Genedisease relationship discovery based on model-driven data integration and database view definition, Bioinformatics, issue.2, pp.25-230, 2009. ,
URL : https://hal.archives-ouvertes.fr/inria-00359111
Recherche de gènes candidats responsables du Syndrome d'Aicardi : Complémentarité des approches expérimentales et bioinformatiques, 2007. ,
ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells, Proceedings of the National Academy of Sciences, vol.107, issue.43, pp.18517-18522, 2010. ,
DOI : 10.1073/pnas.1000975107