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É. Répartition and D. , 25 I.3. Morphologies et anatomies des lichens. 28 I.5. Les différents types de reproduction chez les lichens, Le genre Nephroma, p.32

I. Chapitre and .. Métabolites-lichéniques, 37 II.1. Voies de biosynthèse, 38 II.2. Composés isolés de Nephroma laevigatum, p.42

I. Chapitre and .. Résultats-et-discussion, 43 III.1. Récolte et identification de Nephroma laevigatum 43 III.2. Extractions successives, p.68

I. Chapitre and .. Les-champignons-endolichéniques, 73 I.1. Origine et évolution. 73 I.2. Classification et diversité, p.77

I. Chapitre and D. Résultats, 85 II.1. Isolement et identification des champignons endolichéniques 85 II.2. Description morphologique 90 II.3. Tests préliminaires de production de métabolites 98 II.6. Évaluation des activités biologiques des extraits fongiques 1 ; Gir_20), 114 II.9. Étude phytochimique de la souche Cor_08 : Nemania serpens, p.135

I. Chapitre and .. Récolte-et-identification-de-nephroma-laevigatum, 143 I.1. Observation à la loupe binoculaire et microscope optique, p.143

I. Chapitre and .. Méthodes-analytiques, 150 IV.1. Réactifs et solvants 150 IV.2. Chromatographie sur couche mince analytique (CCM), 150 IV.4. Chromatographie liquide haute performance couplée à la spectrométrie de masse (CLHP-MS) ? Analyses basses résolutions 151 IV.5. Chromatographie liquide haute performance couplée à la spectrométrie de masse (CLHP-MS) ? Analyses hautes résolutions 151 IV.6. Spectroscopie de Résonance Magnétique Nucléaire (RMN) ................................................. 152 IV.7. Spectre de masse haute résolution (SMHR), p.153

V. Chapitre and .. Méthodes-de-séparation, 154 V.1. Chromatographie sur couche mince préparative (CCM prép) 154 V.2. Chromatographie liquide moyenne pression (CLMP), p.154

V. Chapitre and .. Techniques-de-fractionnements, 157 VII.1. Purifications des fractions lichéniques, 157 VII.2. Purifications des fractions issues de 158 VII.3. Purifications des fractions issues de Cor_08, p.159

V. Chapitre and .. Évaluation-des-activités-biologiques, 160 VIII.1. Activités antiprolifératives 160 VIII.2. Activité anti-biofilm fongique, 165 VIII.4. Évaluation de la production d'Espèces Réactives de l'Oxygène (EROs) par Résonance Paramagnétique Électronique, p.169