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Myocardial infarction and sudden death : a population-based approach

Abstract : It becomes clear that efforts should focus on early SCA management. The second part therefore aimed on identifying, among STEMI patients, those at risk of pre-hospital SCA, to plan early SCA management before it occurs. In the e-MUST registry for STEMI in the Greater Paris Area, we identified 5 simple predictors of pre-hospital SCA (young age, absence of obesity, absence of diabetes mellitus, shortness of breath, and short delay between pain onset and call to emergency medical services) that we used to build an SCA prediction score that we validated internally and externally. The first minutes after SCA are the main determinants of its prognosis and should ideally be planned before its occurrence. Anticipation of SCA in STEMI, the main cause of SCA, is feasible, allowing to tailor STEMI management accordingly. Even though the generalizability of this strategy to other causes of SCA remains to be demonstrated, a promising path for decreasing SCA burden can be foreseen.
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Submitted on : Thursday, March 8, 2018 - 10:25:07 AM
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  • HAL Id : tel-01726269, version 1


Nicole Karam. Myocardial infarction and sudden death : a population-based approach. Santé publique et épidémiologie. Université Pierre et Marie Curie - Paris VI, 2017. English. ⟨NNT : 2017PA066331⟩. ⟨tel-01726269⟩



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