Skip to Main content Skip to Navigation
Theses

Surveillance des infections nosocomiales en réanimation : intérêt d'une approche multimodale clinico-biologique et étude d'impact

Abstract : Monitoring the infection acquired in intensive care units (ICU-AI) is a strategic tool for the control of hospital-associated infections. We enhanced the national surveillance database REA-RAISIN with the local diagnosis-related group database. This allows us to have data on the whole hospitalization and assess additional risk factors. The assessment of the impact of these ICU-AI on mortality and length of stay needs appropriate and multiple statistical analysis to take in account various potential bias, including time-dependent bias and competitive risk. This impact is a function of the kind of IAR. Mortality is most affected by bacteremia, more lightly by pneumonia and stay equivalent for patients with or without urinary tract infections. On the other hand, excess of length of stay was the most important for patients with pneumonia and urinary tract infections but moderate for those with bacteremia.Finally, studying the carriage of methicillin-resistant S. aureus appeared insufficient to detect outbreaks and does not measure the risk associated with SASM carriage.
Document type :
Theses
Complete list of metadatas

Cited literature [136 references]  Display  Hide  Download

https://tel.archives-ouvertes.fr/tel-01702284
Contributor : Abes Star :  Contact
Submitted on : Tuesday, February 6, 2018 - 3:48:34 PM
Last modification on : Wednesday, October 14, 2020 - 4:24:23 AM
Long-term archiving on: : Tuesday, May 8, 2018 - 6:32:26 AM

File

LAVIGNE_Thierry_2016_ED414.pdf
Version validated by the jury (STAR)

Identifiers

  • HAL Id : tel-01702284, version 1

Collections

Citation

Thierry Lavigne. Surveillance des infections nosocomiales en réanimation : intérêt d'une approche multimodale clinico-biologique et étude d'impact. Médecine humaine et pathologie. Université de Strasbourg, 2016. Français. ⟨NNT : 2016STRAJ123⟩. ⟨tel-01702284⟩

Share

Metrics

Record views

384

Files downloads

2136